MCID: PRS006
MIFTS: 24

Prostatic Acinar Adenocarcinoma

Categories: Cancer diseases, Reproductive diseases

Aliases & Classifications for Prostatic Acinar Adenocarcinoma

MalaCards integrated aliases for Prostatic Acinar Adenocarcinoma:

Name: Prostatic Acinar Adenocarcinoma 12 15
Acinar Prostate Adenocarcinoma 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3024
NCIt 50 C5596
UMLS 73 C1332139

Summaries for Prostatic Acinar Adenocarcinoma

MalaCards based summary : Prostatic Acinar Adenocarcinoma, also known as acinar prostate adenocarcinoma, is related to bladder diverticulum and renal adenoma. An important gene associated with Prostatic Acinar Adenocarcinoma is TMPRSS2 (Transmembrane Serine Protease 2), and among its related pathways/superpathways are Endometrial cancer and FOXA1 transcription factor network. Affiliated tissues include prostate, and related phenotype is embryo.

Related Diseases for Prostatic Acinar Adenocarcinoma

Diseases related to Prostatic Acinar Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 53)
# Related Disease Score Top Affiliating Genes
1 bladder diverticulum 10.5 AMACR PAX2
2 renal adenoma 10.5 AMACR PAX2
3 urethra adenocarcinoma 10.5 AMACR KLK3
4 urethra clear cell adenocarcinoma 10.5 AMACR KLK3
5 urethral benign neoplasm 10.5 AMACR KLK3
6 seminal vesicle adenocarcinoma 10.5 KLK3 KRT20
7 ovarian mucinous adenocarcinoma 10.5 AMACR KRT20
8 urethral diverticulum 10.4 AMACR KLK3
9 villous adenoma 10.4 KLK3 KRT20
10 prostatic adenoma 10.4 AR KLK3
11 nodular prostate 10.3 AR KLK3
12 endocervical adenocarcinoma 10.3 KRT20 PAX2
13 prostatic hyperplasia, benign 10.3 AR KLK3
14 morpheaform basal cell carcinoma 10.3 AR KRT20
15 androgenic alopecia 10.2 AR KLK3
16 adenocarcinoma in situ 10.2 KRT20 PAX2
17 meibomian cyst 10.2 AR KRT20
18 withdrawal disorder 10.2 AR KLK3
19 paget disease, extramammary 10.2 AR KRT20
20 prostatitis 10.2
21 adenocarcinoma 10.2
22 prostatic hypertrophy 10.2 AR KLK3
23 infiltrative basal cell carcinoma 10.2 AR KRT20
24 nephrogenic adenoma 10.1 AMACR KLK3 PAX2
25 gynecomastia 10.1 AR KLK3
26 pancreatic mucinous cystadenoma 10.1 KRT20 MUC5B
27 female breast cancer 10.1 AR KLK3
28 male reproductive system disease 10.1 AR KLK3
29 sweat gland cancer 10.0 AR KRT20
30 prostate embryonal rhabdomyosarcoma 10.0 KIT KLK3
31 prostate rhabdomyosarcoma 10.0 KIT KLK3
32 cutaneous ganglioneuroma 9.9 KIT KRT20
33 intratubular embryonal carcinoma 9.9 KIT KRT20
34 cystitis cystica 9.9 AR KLK3 KRT20
35 dermoid cyst 9.8 KIT KRT20
36 breast adenoid cystic carcinoma 9.8 AR KIT
37 papillary hidradenoma 9.8 AR KIT
38 reproductive system disease 9.8 AR KLK3
39 large cell neuroendocrine carcinoma 9.7 KIT KRT20
40 oncocytoma 9.6 AMACR KIT
41 suppression of tumorigenicity 12 9.6 AMACR AR KLK3 TMPRSS2
42 male reproductive organ cancer 9.6 AMACR AR KLK3 TMPRSS2
43 clear cell adenocarcinoma 9.6 AMACR KLK3 KRT20 PAX2
44 kidney benign neoplasm 9.6 AMACR KIT PAX2
45 integumentary system cancer 9.6 KIT KRT20
46 rete testis adenocarcinoma 9.5 KIT KLK3 KRT20
47 cell type cancer 9.5 KIT KLK3 KRT20
48 ovarian brenner tumor 9.5 KIT KRT20 PAX2
49 merkel cell carcinoma 9.4 KIT KRT20
50 renal cell carcinoma, papillary, 1 9.2 AMACR KIT

Graphical network of the top 20 diseases related to Prostatic Acinar Adenocarcinoma:



Diseases related to Prostatic Acinar Adenocarcinoma

Symptoms & Phenotypes for Prostatic Acinar Adenocarcinoma

MGI Mouse Phenotypes related to Prostatic Acinar Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 embryo MP:0005380 9.02 AR KIT PAX2 SOCS3 TMPRSS2

Drugs & Therapeutics for Prostatic Acinar Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Prostatic Acinar Adenocarcinoma

Genetic Tests for Prostatic Acinar Adenocarcinoma

Anatomical Context for Prostatic Acinar Adenocarcinoma

MalaCards organs/tissues related to Prostatic Acinar Adenocarcinoma:

41
Prostate

Publications for Prostatic Acinar Adenocarcinoma

Articles related to Prostatic Acinar Adenocarcinoma:

# Title Authors Year
1
The benign mimickers of prostatic acinar adenocarcinoma. ( 27041929 )
2016
2
The prognostic role of ERG immunopositivity in prostatic acinar adenocarcinoma: a study including 454 cases and review of the literature. ( 24406017 )
2013
3
Micropapillary carcinoma: new variant of prostatic acinar adenocarcinoma. ( 23106591 )
2012

Variations for Prostatic Acinar Adenocarcinoma

Expression for Prostatic Acinar Adenocarcinoma

Search GEO for disease gene expression data for Prostatic Acinar Adenocarcinoma.

Pathways for Prostatic Acinar Adenocarcinoma

GO Terms for Prostatic Acinar Adenocarcinoma

Biological processes related to Prostatic Acinar Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.32 KIT SOCS3
2 positive regulation of cell differentiation GO:0045597 9.26 AR SOCS3
3 stem cell differentiation GO:0048863 9.16 KIT PAX2
4 negative regulation of programmed cell death GO:0043069 8.96 KIT PAX2
5 regulation of systemic arterial blood pressure GO:0003073 8.62 AR KLK3

Sources for Prostatic Acinar Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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