Prostatic Cyst disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PRS014 MIFTS: 24	Prostatic Cyst Categories: Reproductive diseases
Genes Tissues Related diseases Publications Drugs Expand all tables

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Aliases & Classifications for Prostatic Cyst

MalaCards integrated aliases for Prostatic Cyst:

Name: Prostatic Cyst ¹² ¹⁵ ⁷⁴

Cyst of Prostate ¹²

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:11133

ICD9CM ³⁶ 600.3

ICD10 ³⁴ N42.83

UMLS ⁷⁴ C1443972

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Summaries for Prostatic Cyst

MalaCards based summary : Prostatic Cyst, also known as cyst of prostate, is related to male infertility and infertility. An important gene associated with Prostatic Cyst is MID2 (Midline 2). The drugs Dutasteride and Tamsulosin have been mentioned in the context of this disorder. Affiliated tissues include kidney and prostate, and related phenotype is Increased cell death HMECs cells.

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Related Diseases for Prostatic Cyst

Diseases related to Prostatic Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)

#	Related Disease	Score	Top Affiliating Genes
1	male infertility	9.9
2	infertility	9.9
3	kidney disease	9.9
4	autosomal dominant polycystic kidney disease	9.9
5	polycystic kidney disease	9.9
6	prostate cancer	9.7
7	prostatitis	9.7
8	sertoli cell tumor	9.7
9	urethral diverticulum	9.7
10	rapidly involuting congenital hemangioma	9.7
11	rectal disease	9.6	KLK3 MID2
12	urethral stricture	9.6	BCL2L10 KLK3

Graphical network of the top 20 diseases related to Prostatic Cyst:

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Symptoms & Phenotypes for Prostatic Cyst

GenomeRNAi Phenotypes related to Prostatic Cyst according to GeneCards Suite gene sharing:

²⁷

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased cell death HMECs cells	GR00103-A-0	8.62	KLK3 MID2

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Drugs & Therapeutics for Prostatic Cyst

Drugs for Prostatic Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Dutasteride

Approved, Investigational

Phase 3

164656-23-9

6918296 152945

Synonyms:

(1S,3aS,3bS,5aR,9aR,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide

(5.alpha.,17.beta.)-N-{2,5 bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1-ene-17-carboxamide

(5a,17b)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide

(5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide

(5α,17β)-N-(2,5-bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide

164656-23-9

17beta-N-(2,5-Bis(trifluoromethyl))phenyl-carbamoyl-4-aza-5alpha-androst-1-en-3-one

745, GG

a,a,a,Alpha',alpha',alpha'-hexafluoro-3-oxo-4-aza-5a-androst-1-ene-17b-carboxy-2',5'-xylidide

AC1L49EM

AC1OCF98

alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2',5'-xylidide

alpha,alpha,alpha,Alpha',alpha',alpha'-hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2',5'-xylidide

Avodart

Avodart (TN)

Avodart, Dutasteride

Avolve

Bio-0167

C27H30F6N2O2

CHEBI:132773

CHEMBL1200969

CHEMBL283245

CID152945

CID6918296

CID9914880

D03820

DB01126

Duagen

Dutasterida

Dutasteride

Dutasteride (JAN/USAN/INN)

Dutasteride [USAN]

FT-0080365

GG 745

GG-745

GI 198745

GI-198745

GI-198745X

LS-173584

MolPort-003-666-660

MolPort-003-847-041

N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide

NSC740477

S1202_Selleck

UNII-O0J6XJN02I

ZINC03932831

α,α,α,alpha',alpha',alpha'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidide

α,α,α,α',α',α'-hexafluoro-3-oxo-4-aza-5α-androst-1-ene-17β-carboxy-2',5'-xylidide

Tamsulosin

Approved, Investigational

Phase 3

106133-20-4

129211

Synonyms:

(−)-tamsulosin

(R)-(−)-tamsulosin

(R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulphonamide

106133-20-4

5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide

5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide

5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide

5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide

5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide

5-[2-[2-(2-Ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulphonamide

5-{(2R)-2-[(2-{[2-(ethyloxy)phenyl]oxy}ethyl)amino]propyl}-2-(methyloxy)benzenesulfonamide

AC1L2V76

BIDD:GT0261

C07124

C20H28N2O5S

CHEBI:9398

CHEMBL836

CID129211

D08560

DB00706

Flomax

Flomax (TN)

Flowmax

FT-0082894

Harnal

HMS2090P15

LS-31578

MolPort-003-850-388

NCGC00167442-01

Omnic

Pradif

STK626950

Tamsolusin

Tamsulon

Tamsulon (TN)

tamsulosin

Tamsulosin

TAMSULOSIN

Tamsulosin (INN)

Tamsulosin [INN:BAN]

Tamsulosin hydrochloride

Tamsulosina

Tamsulosina [INN-Spanish]

Tamsulosine

Tamsulosine [INN-French]

Tamsulosinum

Tamsulosinum [INN-Latin]

UNII-G3P28OML5I

YM-617

5-alpha Reductase Inhibitors

Phase 3

Adrenergic alpha-1 Receptor Antagonists

Phase 3

Adrenergic Agents

Phase 3

Steroid Synthesis Inhibitors

Phase 3

Hormones

Phase 3

Adrenergic alpha-Antagonists

Phase 3

Hormone Antagonists

Phase 3

Neurotransmitter Agents

Phase 3

Adrenergic Antagonists

Phase 3

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 3

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Study to Compare the Efficacy and Safety of Combination Treatment With Dutasteride and Tamsulosin With Tamsulosin Monotherapy, in Men With Moderate to Severe Benign Prostatic Hyperplasia	Completed	NCT02058368	Phase 3	Dutasteride 0.5mg capsules;Dutasteride placebo capsules;Tamsulosin 0.2mg tablets;Disintegrating placebo tamsulosin tablet

Search NIH Clinical Center for Prostatic Cyst

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Genetic Tests for Prostatic Cyst

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Anatomical Context for Prostatic Cyst

MalaCards organs/tissues related to Prostatic Cyst:

⁴²

Kidney, Prostate

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Publications for Prostatic Cyst

Articles related to Prostatic Cyst:

(show all 37)

#	Title	Authors	Year
1	Prostatic cyst in autosomal dominant polycystic kidney disease: unusual association. ( 30954962 )	Sood V...Ramachandran R	2019
2	TRUS-guided needle drainage of a prostatic cyst for treatment of male infertility. ( 30094189 )	Graff J...Spear K	2018
3	Prostatic cyst in general practice: A case report and literature review. ( 29489699 )	Qiu Y...Ren J	2018
4	A large, benign prostatic cyst presented with an extremely high serum prostate-specific antigen level. ( 26746834 )	Chen HK...Pemberton R	2016
5	Benign or Malignant? Two Case Reports of Gigantic Prostatic Cyst. ( 27500085 )	Yu J...Wang Y	2016
6	Severe lower urinary tract symptoms due to anteriorly located midline prostatic cyst arising from the bladder neck in a young male: case report. ( 27680216 )	G?ra?a? A...Aydur E	2016
7	Midline Prostatic Cyst Marsupialization Using Holmium Laser. ( 26101688 )	Kilinc M...Kandemir A	2015
8	A novel surgical management for male infertility secondary to midline prostatic cyst. ( 25888036 )	Cheng G...Wang Z	2015
9	Midline prostatic cyst in a young man with lower urinary tract symptoms. ( 25535235 )	Saha B...Mitra N	2014
10	Disorders of bladder depletion in a young man because of a prostatic cyst: a case report. ( 22649962 )	Dell'Atti L	2012
11	Prostatic cyst causing severe infravesical obstruction in a young patient. ( 22090057 )	Dogan B...Balbay MD	2011
12	Pathology in practice. "Urine" sample collected by cystocentesis probably fluid aspirated from a prostatic cyst. ( 20433393 )	Driver TL...Swenson CL	2010
13	An anteriorly positioned midline prostatic cyst resulting in lower urinary tract symptoms. ( 21120223 )	Lee JY...Choi HY	2010
14	Intraabdominal torsion of a neoplastic testicle and prostatic cyst in a cryptorchid dog. ( 17929707 )	Mostachio GQ...Toniollo GH	2007
15	Prostatic cyst arising around the bladder neck-cause of bladder outlet obstruction: two case reports. ( 17628939 )	Tambo M...Higashihara E	2007
16	Prostatic Cyst : Association with Autosomal Dominant Polycystic Kidney Disease. ( 27407908 )	Hooda AK...Narula AS	2006
17	Intraurethral prostatic cyst: a rare cause of infravesical obstruction. ( 15160538 )	Yildirim I...Peker AF	2003
18	Infravesical obstruction due to benign intraurethral prostatic cyst. ( 12589102 )	Chang SG...Lim JW	2003
19	Transrectal ultrasound-guided puncture, drainage, and minocycline hydrochloride sclerotherapy for the symptomatic prostatic cyst. ( 12490027 )	Saito S	2002
20	Treatment of large prostatic cyst with retropubic insertion of a fat tissue flap. ( 10893615 )	Anding R...Allhoff EP	2000
21	Clinical features and management of anterior intraurethral prostatic cyst. ( 10754151 )	Issa MM...Petros JA	1999
22	Transurethral deroofing of midline prostatic cyst for subfertile men. ( 10469699 )	Cornel EB...Meuleman EJ	1999
23	A müllerian prostatic cyst protruding into the base of the urinary bladder. ( 9644795 )	Barzilai M...Ginesin Y	1998
24	Primary male infertility caused by congenital prostatic cyst: sonographic and magnetic resonance imaging findings. ( 9792988 )	Aalame NM...Kubik-Huch RA	1998
25	Transurethral marsupialization of a medial prostatic cyst in patients with prostatitis-like symptoms. ( 8632560 )	Dik P...Boon TA	1996
26	Prostatic cyst. An unusual but important finding in male urogenital dysfunction. ( 8578282 )	Zhu JP...Meyhoff HH	1995
27	Posterior urethral diverticulum presenting as a midline prostatic cyst: sonographic and MRI appearance. ( 7894304 )	Wachsberg RH...Irwin R	1995
28	Congenital prostatic cyst causing ejaculatory duct obstruction: management by transrectal cyst aspiration. ( 8483234 )	Stricker HJ...Faerber GJ	1993
29	Intraoperative transrectal ultrasonography in the management of ejaculatory duct obstruction caused by midline prostatic cyst. ( 8478467 )	Queralt JA...Cronan MS	1993
30	Prostatic cyst: report of 2 cases. ( 2677224 )	Chang SC...Lee F	1989
31	Prostatic cyst and concurrent Sertoli cell tumor in a dog. ( 3372340 )	Spackman CJ...Roth L	1988
32	Ultrasound diagnosis of a prostatic cyst causing acute urinary retention. ( 3302308 )	Hamilton S...Fitzpatrick JM	1987
33	What is your diagnosis? Hypertrophy of the prostate and calcified prostatic cyst. ( 6208179 )	Porter RS...Bahr RJ	1984
34	Post-gonococcal prostatic cyst: an unusual abdominal mass. ( 7284725 )	Bucknall TE...Lord MD	1981
35	Prostatic cyst. ( 5462988 )	Llorico BF	1970
36	Congenital cyst of prostate communicating with right vas and rudimentary right ureter; case report. ( 20283475 )	DEES JE	1947
37	Case of Cyst of Prostate. ( 19983417 )	Thomson-Walker J	1923

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Genes for Prostatic Cyst

Genes related to Prostatic Cyst (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	MID2	Midline 2	Protein Coding	16.17	DISEASES inferred ¹⁵
2	BCL2L10	BCL2 Like 10	Protein Coding	16.05	DISEASES inferred ¹⁵
3	KLK3	Kallikrein Related Peptidase 3	Protein Coding	14.8	DISEASES inferred ¹⁵

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Variations for Prostatic Cyst

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Expression for Prostatic Cyst

Search GEO for disease gene expression data for Prostatic Cyst.

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Pathways for Prostatic Cyst

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GO Terms for Prostatic Cyst

Molecular functions related to Prostatic Cyst according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	protein homodimerization activity	GO:0042803	8.96	BCL2L10 MID2
2	protein heterodimerization activity	GO:0046982	8.62	BCL2L10 MID2

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Sources for Prostatic Cyst

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²⁵ GeneReviews

²⁶ Genetics Home Reference

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²⁸ GEO DataSets

²⁹ GO

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³⁴ ICD10

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⁵⁹ OMIM via Orphanet

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⁶⁹ SNOMED-CT

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⁷¹ SNOMED-CT via Orphanet

⁷² TGDB

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⁷⁵ UMLS via Orphanet

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