MCID: PRS014
MIFTS: 24

Prostatic Cyst

Categories: Reproductive diseases

Aliases & Classifications for Prostatic Cyst

MalaCards integrated aliases for Prostatic Cyst:

Name: Prostatic Cyst 12 15 74
Cyst of Prostate 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11133
ICD9CM 36 600.3
ICD10 34 N42.83
UMLS 74 C1443972

Summaries for Prostatic Cyst

MalaCards based summary : Prostatic Cyst, also known as cyst of prostate, is related to male infertility and infertility. An important gene associated with Prostatic Cyst is MID2 (Midline 2). The drugs Dutasteride and Tamsulosin have been mentioned in the context of this disorder. Affiliated tissues include kidney and prostate, and related phenotype is Increased cell death HMECs cells.

Related Diseases for Prostatic Cyst

Diseases related to Prostatic Cyst via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 12)
# Related Disease Score Top Affiliating Genes
1 male infertility 9.9
2 infertility 9.9
3 kidney disease 9.9
4 autosomal dominant polycystic kidney disease 9.9
5 polycystic kidney disease 9.9
6 prostate cancer 9.7
7 prostatitis 9.7
8 sertoli cell tumor 9.7
9 urethral diverticulum 9.7
10 rapidly involuting congenital hemangioma 9.7
11 rectal disease 9.6 KLK3 MID2
12 urethral stricture 9.6 BCL2L10 KLK3

Graphical network of the top 20 diseases related to Prostatic Cyst:



Diseases related to Prostatic Cyst

Symptoms & Phenotypes for Prostatic Cyst

GenomeRNAi Phenotypes related to Prostatic Cyst according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased cell death HMECs cells GR00103-A-0 8.62 KLK3 MID2

Drugs & Therapeutics for Prostatic Cyst

Drugs for Prostatic Cyst (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dutasteride Approved, Investigational Phase 3 164656-23-9 6918296 152945
2
Tamsulosin Approved, Investigational Phase 3 106133-20-4 129211
3 5-alpha Reductase Inhibitors Phase 3
4 Adrenergic alpha-1 Receptor Antagonists Phase 3
5 Adrenergic Agents Phase 3
6 Steroid Synthesis Inhibitors Phase 3
7 Hormones Phase 3
8 Adrenergic alpha-Antagonists Phase 3
9 Hormone Antagonists Phase 3
10 Neurotransmitter Agents Phase 3
11 Adrenergic Antagonists Phase 3
12 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study to Compare the Efficacy and Safety of Combination Treatment With Dutasteride and Tamsulosin With Tamsulosin Monotherapy, in Men With Moderate to Severe Benign Prostatic Hyperplasia Completed NCT02058368 Phase 3 Dutasteride 0.5mg capsules;Dutasteride placebo capsules;Tamsulosin 0.2mg tablets;Disintegrating placebo tamsulosin tablet

Search NIH Clinical Center for Prostatic Cyst

Genetic Tests for Prostatic Cyst

Anatomical Context for Prostatic Cyst

MalaCards organs/tissues related to Prostatic Cyst:

42
Kidney, Prostate

Publications for Prostatic Cyst

Articles related to Prostatic Cyst:

(show all 37)
# Title Authors Year
1
Prostatic cyst in autosomal dominant polycystic kidney disease: unusual association. ( 30954962 )
2019
2
TRUS-guided needle drainage of a prostatic cyst for treatment of male infertility. ( 30094189 )
2018
3
Prostatic cyst in general practice: A case report and literature review. ( 29489699 )
2018
4
A large, benign prostatic cyst presented with an extremely high serum prostate-specific antigen level. ( 26746834 )
2016
5
Benign or Malignant? Two Case Reports of Gigantic Prostatic Cyst. ( 27500085 )
2016
6
Severe lower urinary tract symptoms due to anteriorly located midline prostatic cyst arising from the bladder neck in a young male: case report. ( 27680216 )
2016
7
Midline Prostatic Cyst Marsupialization Using Holmium Laser. ( 26101688 )
2015
8
A novel surgical management for male infertility secondary to midline prostatic cyst. ( 25888036 )
2015
9
Midline prostatic cyst in a young man with lower urinary tract symptoms. ( 25535235 )
2014
10
Disorders of bladder depletion in a young man because of a prostatic cyst: a case report. ( 22649962 )
2012
11
Prostatic cyst causing severe infravesical obstruction in a young patient. ( 22090057 )
2011
12
Pathology in practice. "Urine" sample collected by cystocentesis probably fluid aspirated from a prostatic cyst. ( 20433393 )
2010
13
An anteriorly positioned midline prostatic cyst resulting in lower urinary tract symptoms. ( 21120223 )
2010
14
Intraabdominal torsion of a neoplastic testicle and prostatic cyst in a cryptorchid dog. ( 17929707 )
2007
15
Prostatic cyst arising around the bladder neck-cause of bladder outlet obstruction: two case reports. ( 17628939 )
2007
16
Prostatic Cyst : Association with Autosomal Dominant Polycystic Kidney Disease. ( 27407908 )
2006
17
Intraurethral prostatic cyst: a rare cause of infravesical obstruction. ( 15160538 )
2003
18
Infravesical obstruction due to benign intraurethral prostatic cyst. ( 12589102 )
2003
19
Transrectal ultrasound-guided puncture, drainage, and minocycline hydrochloride sclerotherapy for the symptomatic prostatic cyst. ( 12490027 )
2002
20
Treatment of large prostatic cyst with retropubic insertion of a fat tissue flap. ( 10893615 )
2000
21
Clinical features and management of anterior intraurethral prostatic cyst. ( 10754151 )
1999
22
Transurethral deroofing of midline prostatic cyst for subfertile men. ( 10469699 )
1999
23
A müllerian prostatic cyst protruding into the base of the urinary bladder. ( 9644795 )
1998
24
Primary male infertility caused by congenital prostatic cyst: sonographic and magnetic resonance imaging findings. ( 9792988 )
1998
25
Transurethral marsupialization of a medial prostatic cyst in patients with prostatitis-like symptoms. ( 8632560 )
1996
26
Prostatic cyst. An unusual but important finding in male urogenital dysfunction. ( 8578282 )
1995
27
Posterior urethral diverticulum presenting as a midline prostatic cyst: sonographic and MRI appearance. ( 7894304 )
1995
28
Congenital prostatic cyst causing ejaculatory duct obstruction: management by transrectal cyst aspiration. ( 8483234 )
1993
29
Intraoperative transrectal ultrasonography in the management of ejaculatory duct obstruction caused by midline prostatic cyst. ( 8478467 )
1993
30
Prostatic cyst: report of 2 cases. ( 2677224 )
1989
31
Prostatic cyst and concurrent Sertoli cell tumor in a dog. ( 3372340 )
1988
32
Ultrasound diagnosis of a prostatic cyst causing acute urinary retention. ( 3302308 )
1987
33
What is your diagnosis? Hypertrophy of the prostate and calcified prostatic cyst. ( 6208179 )
1984
34
Post-gonococcal prostatic cyst: an unusual abdominal mass. ( 7284725 )
1981
35
Prostatic cyst. ( 5462988 )
1970
36
Congenital cyst of prostate communicating with right vas and rudimentary right ureter; case report. ( 20283475 )
1947
37
Case of Cyst of Prostate. ( 19983417 )
1923

Variations for Prostatic Cyst

Expression for Prostatic Cyst

Search GEO for disease gene expression data for Prostatic Cyst.

Pathways for Prostatic Cyst

GO Terms for Prostatic Cyst

Molecular functions related to Prostatic Cyst according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 8.96 BCL2L10 MID2
2 protein heterodimerization activity GO:0046982 8.62 BCL2L10 MID2

Sources for Prostatic Cyst

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
Content
Loading form....