Prostatitis disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: PRS047 MIFTS: 56	Prostatitis Categories: Reproductive diseases
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Aliases & Classifications for Prostatitis

MalaCards integrated aliases for Prostatitis:

Name: Prostatitis ¹² ⁷⁶ ⁵⁵ ⁴⁴ ¹⁵ ⁷³

Classifications:

MalaCards categories:
Anatomical: Reproductive diseases

See all MalaCards categories (disease lists)

ICD10: ³³

Diseases of the genitourinary system

Diseases of male genital organs

Inflammatory diseases of prostate

Inflammatory disease of prostate, unspecified

External Ids:

Disease Ontology ¹² DOID:14654

ICD10 ³³ N41 N41.9

ICD9CM ³⁵ 601 601.9

MeSH ⁴⁴ D011472

NCIt ⁵⁰ C26866

SNOMED-CT ⁶⁸ 9713002

UMLS ⁷³ C0033581

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Summaries for Prostatitis

MalaCards based summary : Prostatitis is related to prostate cancer and prostate disease, and has symptoms including prostatism An important gene associated with Prostatitis is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are PEDF Induced Signaling and TGF-Beta Pathway. The drugs Saw palmetto and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include prostate, testes and brain, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : ⁷⁶ Prostatitis is inflammation of the prostate gland. Prostatitis is classified into acute, chronic,... more...

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Related Diseases for Prostatitis

Diseases related to Prostatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1163)

#	Related Disease	Score	Top Affiliating Genes
1	prostate cancer	34.5	KLK3 MSMB NKX3-1 PROS1 TGFB1 VDR
2	prostate disease	34.2	KLK3 MSMB NKX3-1
3	prostate sarcoma	34.0	KLK3 NKX3-1
4	nephrogenic adenoma	30.4	KLK3 NKX3-1
5	spinal cord injury	30.3	IL6 TGFB1 TNF
6	osteoarthritis	30.3	IL1B IL6 TGFB1 TNF
7	cystitis	30.2	CXCL8 IL6 TNF
8	alpha-2-macroglobulin deficiency	30.2	KLK3 PROS1
9	breast disease	30.0	KLK3 TGFB1 TNF
10	acute cystitis	30.0	CXCL8 IL6 KLK3
11	anterior uveitis	29.9	IL6 TNF
12	myeloma, multiple	29.9	CXCL8 IL2 IL6 TNF
13	purpura	29.8	IL6 PROS1 TNF
14	osteoporosis	29.7	IL1B IL6 TGFB1 TNF VDR
15	pulmonary tuberculosis	29.7	VDR TNF IL2 IL10
16	bone disease	29.6	IL1B IL6 TNF VDR
17	submandibular gland disease	29.6	KLK3 TGFB1
18	obstructive jaundice	29.6	CXCL8 IL6 TNF
19	microscopic polyangiitis	29.5	IL10 TNF
20	paraneoplastic syndromes	29.5	IL1B IL6
21	schistosomiasis	29.5	IL10 IL2 TNF
22	cardiogenic shock	29.5	IL6 TNF
23	fasciitis	29.5	CXCL8 IL6 TNF
24	arteries, anomalies of	29.4	IL1B IL6 TNF
25	oral tuberculosis	29.4	IL2 TNF
26	acute pyelonephritis	29.3	CXCL8 IL10 IL6
27	end stage renal failure	29.3	IL6 TGFB1 TNF
28	chlamydia	29.3	CXCL8 IL10 IL1B IL6 TNF
29	pulmonary disease, chronic obstructive	29.3	CXCL8 IL6 TGFB1 TNF
30	pouchitis	29.3	CXCL8 IL10
31	paracoccidioidomycosis	29.3	IL10 IL2 IL6 TNF
32	posterior urethral valves	29.3	TNF TGFB1 IL6
33	bacterial sepsis	29.2	CXCL8 IL10 TNF
34	melioidosis	29.2	IL10 IL6 TNF
35	endometriosis	29.2	CXCL8 IL1B IL6
36	localized scleroderma	29.2	IL6 TGFB1 TNF
37	fatty liver disease	29.2	TNF IL6 IL1B CXCL8
38	endocarditis	29.2	TNF IL6 IL10 CXCL8
39	sarcoidosis 1	29.2	IL1B IL2 TNF
40	periodontal disease	29.1	TNF IL6 IL1B CXCL8
41	mycobacterium tuberculosis 1	29.1	IL10 TNF VDR
42	acute pancreatitis	29.1	CXCL8 IL10 IL6
43	tropical spastic paraparesis	29.1	IL10 IL2 IL6
44	necrotizing fasciitis	29.1	IL6 IL2 CXCL8
45	myasthenia gravis	29.0	IL10 IL2 TNF
46	exanthem	29.0	IL2 IL6 TNF
47	pyelonephritis	29.0	CXCL8 IL10 IL1B IL6 TNF
48	chronic fatigue syndrome	29.0	IL10 IL1B IL2 IL6 TGFB1 TNF
49	osteomyelitis	29.0	CXCL8 IL10 IL1B IL6 TNF
50	vaginitis	28.9	IL6 IL1B CXCL8

Comorbidity relations with Prostatitis via Phenotypic Disease Network (PDN):

Acute Cystitis	Bladder Neck Obstruction
Chronic Myocardial Ischemia	Epididymo-Orchitis
Ischemic Heart Disease	Prostate Calculus
Prostate Cancer	Prostatic Hypertrophy
Urethral Stricture	Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Prostatitis:

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Symptoms & Phenotypes for Prostatitis

UMLS symptoms related to Prostatitis:

prostatism

GenomeRNAi Phenotypes related to Prostatitis according to GeneCards Suite gene sharing:

²⁶

#	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-1	9.77	ADRA1A CXCL8 IL10 IL1B IL2 TGFB1
2	Synthetic lethal with MLN4924 (a NAE inhibitor)	GR00250-A-2	9.77	ADRA1A CXCL8 IL10 IL1B IL2 TGFB1

MGI Mouse Phenotypes related to Prostatitis:

⁴⁶ (show all 12)

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cardiovascular system	MP:0005385	10.16	ADRA1A IL10 IL1B IL2 IL6 PROS1
2	homeostasis/metabolism	MP:0005376	10.13	ADRA1A IL10 IL1B IL2 IL6 NKX3-1
3	endocrine/exocrine gland	MP:0005379	10.08	IL10 IL2 IL6 MSMB NKX3-1 TGFB1
4	hematopoietic system	MP:0005397	10.06	IL10 IL1B IL2 IL6 PROS1 TGFB1
5	digestive/alimentary	MP:0005381	10.04	IL10 IL2 IL6 NKX3-1 TGFB1 TNF
6	mortality/aging	MP:0010768	10.02	ADRA1A IL10 IL1B IL2 IL6 NKX3-1
7	integument	MP:0010771	9.95	IL10 IL1B IL6 PROS1 TGFB1 TNF
8	liver/biliary system	MP:0005370	9.85	IL10 IL2 IL6 PROS1 TGFB1 TNF
9	muscle	MP:0005369	9.8	ADRA1A IL10 IL6 PROS1 TGFB1 TNF
10	neoplasm	MP:0002006	9.76	IL10 IL1B IL2 IL6 MSMB NKX3-1
11	reproductive system	MP:0005389	9.56	IL10 IL2 IL6 MSMB NKX3-1 TGFB1
12	skeleton	MP:0005390	9.17	IL10 IL1B IL6 NKX3-1 TGFB1 TNF

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Drugs & Therapeutics for Prostatitis

Drugs for Prostatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 155)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Saw palmetto

Approved, Experimental, Investigational

Phase 4,Phase 3

Acetaminophen

Approved

Phase 4

103-90-2

1983

Cycloserine

Approved

Phase 4,Phase 3

68-41-7

6234 401

Testosterone undecanoate

Approved, Investigational

Phase 4

5949-44-0

Testosterone enanthate

Approved

Phase 4

315-37-7

9416

Testosterone

Approved, Investigational

Phase 4

58-22-0

6013

Methyltestosterone

Approved

Phase 4

58-18-4

6010

Acetylcholine

Approved

Phase 4,Phase 3,Phase 2

51-84-3

187

Ciprofloxacin

Approved, Investigational

Phase 4,Phase 3

85721-33-1

2764

Tadalafil

Approved, Investigational

Phase 4

171596-29-5

110635

Trimethoprim

Approved, Vet_approved

Phase 4

738-70-5

5578

Sulfamethoxazole

Approved

Phase 4

723-46-6

5329

leucovorin

Approved

Phase 4

58-05-9

6006 143

Amoxicillin

Approved, Vet_approved

Phase 4

26787-78-0

33613

Fosfomycin

Approved

Phase 4

23155-02-4

446987

Gabapentin

Approved, Investigational

Phase 4

60142-96-3

3446

gamma-Aminobutyric acid

Approved, Investigational

Phase 4

56-12-2

119

Cilastatin

Approved, Investigational

Phase 4

82009-34-5

6435415 5280454

Cefotaxime

Approved

Phase 4

63527-52-6

456256 5742673

Cefoxitin

Approved

Phase 4

35607-66-0

441199

Imipenem

Approved

Phase 4

74431-23-5, 64221-86-9

104838

Folic Acid

Approved, Nutraceutical, Vet_approved

Phase 4

59-30-3

6037

Citric Acid

Approved, Nutraceutical, Vet_approved

Phase 4

77-92-9

311

Prulifloxacin

Investigational

Phase 4,Phase 2

123447-62-1

Peripheral Nervous System Agents

Phase 4,Phase 3,Phase 2

Cholinergic Agents

Phase 4,Phase 3,Phase 2,Not Applicable

Neurotransmitter Agents

Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1

Central Nervous System Depressants

Phase 4,Phase 3,Phase 2,Phase 1

Psychotropic Drugs

Phase 4,Phase 3

Anticonvulsants

Phase 4,Phase 3

Anti-Anxiety Agents

Phase 4,Phase 3

calcium channel blockers

Phase 4,Phase 3

Calcium, Dietary

Phase 4,Phase 3,Phase 2

Analgesics

Phase 4,Phase 3,Phase 2

Tranquilizing Agents

Phase 4,Phase 3

Antibiotics, Antitubercular

Phase 4,Phase 3,Phase 2

Antitubercular Agents

Phase 4,Phase 3

Anti-Infective Agents

Phase 4,Phase 3,Phase 2,Phase 1

Topoisomerase Inhibitors

Phase 4,Phase 3,Phase 2

Acidophilus

Phase 4

Nucleic Acid Synthesis Inhibitors

Phase 4,Phase 3,Phase 2

Saw palmetto extract

Phase 4,Phase 3

Fluoroquinolones

Phase 4,Phase 3,Phase 2

Anti-Bacterial Agents

Phase 4,Phase 3,Phase 2

Anti-Infective Agents, Urinary

Phase 4,Phase 3,Phase 2

Renal Agents

Phase 4,Phase 3,Phase 2

Antimetabolites

Phase 4,Phase 3

Antineoplastic Agents, Hormonal

Phase 4

Pharmaceutical Solutions

Phase 4,Phase 3

Testosterone 17 beta-cypionate

Phase 4

Interventional clinical trials:

(show top 50) (show all 86)

#	Name	Status	NCT ID	Phase	Drugs
1	Treatment of Chronic Bacterial Prostatitis	Completed	NCT02130713	Phase 4	Third generation fluoroquinolone
2	Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain	Completed	NCT02385266	Phase 4	D-Cycloserine;Placebo (for D-cycloserine)
3	TRT on BPH Hypoganadal MetS Patients. Florence-PROTEST	Completed	NCT02366975	Phase 4	Testosterone gel 2%
4	Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication	Completed	NCT02246361	Phase 4
5	Botox as a Treatment for Interstitial Cystitis in Women	Completed	NCT00194610	Phase 4	Botox
6	Effect of 12 Weeks Treatment With Tadalafil vs Placebo on Lower Urinary Tract Symptoms	Recruiting	NCT02252367	Phase 4	Tadalafil
7	Cotrimoxazole Prophylaxis in Transurethral Resection or Greenlight Laser Vaporisation of the Prostate	Recruiting	NCT03633643	Phase 4	oral applications of TMP/SMX 800/160 mg (Nopil forte® tablets);oral applications of Placebo
8	Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy.	Not yet recruiting	NCT03228108	Phase 4	Ciprofloxacin;Trimethoprim/Sulfamethoxazole;Fosfomycin;Pivmecillinam/augmentin
9	Effectiveness of Sympathetic Plexus Block on Male Pelvic Pain (Prostatitis, Prostatodynia)	Suspended	NCT00194636	Phase 4
10	Trial of Viagra' in Men With Chronic Pelvic Pain Syndrome Type III	Terminated	NCT00194597	Phase 4	Viagra (sildenafil citrate)
11	Botox as a Treatment for Chronic Male Pelvic Pain Syndrome	Terminated	NCT00194623	Phase 4	Botulinum Toxin A (Botox)
12	Efficacy of Gralise® for Chronic Pelvic Pain	Terminated	NCT01678911	Phase 4	Gralise
13	Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli	Terminated	NCT02474706	Phase 4	Cefoxitin;imipenem
14	Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)	Unknown status	NCT00371033	Phase 3	Pregabalin;Placebo
15	Efficacy Study of a Standardized Pollen Extract Preparation (Cernilton) to Treat Inflammatory Chronic Prostatitis-Chronic Pelvic Pain Syndrome (CP-CPPS)	Completed	NCT00919893	Phase 3	Cernilton;Placebo
16	Efficacy Study of Acupuncture to Relieve Symptoms of Chronic Prostatitis	Completed	NCT00260637	Phase 2, Phase 3
17	An Effectiveness and Safety Study for Levofloxacin in Chronic Prostatitis	Completed	NCT00402688	Phase 3	levofloxacin;levofloxacin;levofloxacin
18	A Study to Evaluate the Safety and Effectiveness of Levofloxacin Compared With Ciprofloxacin in Patients With Chronic Bacterial Prostatitis	Completed	NCT00236808	Phase 3	levofloxacin
19	Levofloxacin, Chronic Bacterial Prostatitis	Completed	NCT00277511	Phase 3	Levofloxacin
20	Trial to Compare Alfuzosin Versus Placebo in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome	Completed	NCT00103402	Phase 3	Alfuzosin
21	Levofloxacin For The Management Of Patients With Abnormal Prostate Specific Antigen (PSA)	Completed	NCT00169585	Phase 3	Levofloxacin oral tablets
22	Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO)	Completed	NCT00495651	Phase 3	Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis;Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis
23	Complementary and Alternative Medicine for Urological Symptoms(CAMUS)	Completed	NCT00603304	Phase 3	Saw Palmetto - first 24 weeks;Placebo - first 24 weeks;Saw Palmetto - weeks 24 - 48;Placebo - weeks 24 - 48;Saw Palmetto - weeks 48 - 72;Placebo - weeks 48 - 72
24	"REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk	Completed	NCT00056407	Phase 3	Dutasteride;Placebo
25	Benign Prostatic Hyperplasia Trial With Dutasteride And Tamsulosin Combination Treatment	Completed	NCT00090103	Phase 3	dutasteride 0.5mg once daily for 4 years;tamsulosin 0.4mg once daily for 4 years
26	Effects of Proxelan Somministration in Patients With Chronic Prostatitis	Recruiting	NCT03629769	Phase 3	Proxelan
27	JALYN for Benign Prostatic Hyperplasia (BPH) and Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)	Terminated	NCT01830829	Phase 3	Jalyn;Placebo
28	Botulinum Toxin Type A for the Treatment of Male Chronic Pelvic Pain Syndrome	Terminated	NCT00464373	Phase 3	Botulinum Toxin Type A;Placebo
29	Efficacy and Tolerability of Delamanid, Linezolid, Pyrazinamide and Levofloxacin	Withdrawn	NCT02975570	Phase 3	Delamanid;Linezolid;Levofloxacin;Pyrazinamide;WHO MDR-TB regimen
30	Laparoscopic Prostatectomy for Chronic Prostatitis	Unknown status	NCT00775515	Phase 2
31	Use of Silodosin to Treat Moderate to Severe Abacterial Chronic Prostatitis/Chronic Pelvic Pain Syndrome.	Completed	NCT00740779	Phase 2	Silodosin 8 mg;Placebo;Silodosin 4 mg
32	An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome	Completed	NCT00701311	Phase 2	CC-10004
33	Botox for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)	Completed	NCT00529386	Phase 2	Botox;Lidocaine
34	An Efficacy And Safety Study Of Tanezumab For The Treatment Of Pain Associated With Chronic Abacterial Prostatitis	Completed	NCT00826514	Phase 2	Tanezumab;Placebo
35	An Effectiveness and Safety Study of ELMIRON (Pentosan Polysulfate Sodium) for the Treatment of Chronic Non-Bacterial Inflammation of the Prostate Gland	Completed	NCT00236990	Phase 2	pentosan polysulfate sodium
36	A Clinical Study to Investigate the Efficacy, Safety and Pharmacokinetics of ASP3652 in Patients With Chronic Abacterial Prostatitis / Chronic Pelvic Pain Syndrome (CP/CPPS)	Completed	NCT01391338	Phase 2	ASP3652;Placebo
37	A Pilot Study of Norfloxacin for Hepatopulmonary Syndrome	Completed	NCT00362752	Phase 2	Norfloxacin;Placebo
38	Intravesical Epirubicin Plus BCG to Prevent the Recurrence of Transitional Cell Carcinoma of Bladder	Completed	NCT00343356	Phase 2	Trement
39	Safety/Tolerability Study of Alcohol Injection for Treatment of BPH (Enlarged Prostate)	Completed	NCT00037141	Phase 1, Phase 2	dehydrated alcohol
40	Prulifloxacin in Chronic Bacterial Prostatitis (CBP)	Recruiting	NCT03201796	Phase 2	Prulifloxacin 600 mg;Levofloxacin 500mg
41	Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy	Recruiting	NCT02961114	Phase 1, Phase 2
42	Urethral Sterilization With Chlorhexidine Digluconate to Facilitate Primary Repair & Same-Session Implantation	Recruiting	NCT03614429	Phase 2	Chlorhexidine gel will be prepared according to an international product Instillagel®
43	Open-Label Study of Thalidomide for Chronic Prostatitis/Chronic Pelvic Pain	Terminated	NCT00301405	Phase 2	Thalidomide
44	Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome	Terminated	NCT03500159	Phase 2	AQX-1125 200 mg;Placebo
45	Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis	Unknown status	NCT00913315	Not Applicable	tolterodine;tamsulosin;placebo
46	Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndromes	Unknown status	NCT02588274	Not Applicable
47	Efficacy of Extracorporal Shock Wave Therapy in Patient With Chronic Non-bacterial Prostatitis / Chronic Pelvic Pain Syndrome	Unknown status	NCT01714830	Not Applicable
48	Shocking Therapy for Chronic Pelvic Pain Syndrome	Unknown status	NCT01828996	Not Applicable
49	Effect of Pumpkin Seeds Phonophoresis on Chronic Non-bacterial Prostatitis	Completed	NCT03461263	Not Applicable
50	Non Interventional Study of Levofloxacin in Chronic Prostatitis	Completed	NCT02711943		Levofloxacin 500

Search NIH Clinical Center for Prostatitis

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :

ciprofloxacin

Cochrane evidence based reviews: prostatitis

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Genetic Tests for Prostatitis

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Anatomical Context for Prostatitis

MalaCards organs/tissues related to Prostatitis:

⁴¹

Prostate, Testes, Brain, Spinal Cord, Kidney, Heart, Pituitary

Sources

Publications for Prostatitis

Articles related to Prostatitis:

(show top 50) (show all 1128)

#	Title	Authors	Year
1	Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial. ( 29948596 )	Ying J....Zhang Z.J.	2018
2	Identification and preliminary study of immunogens involved in autoimmune prostatitis in human males. ( 29947032 )	Lu J.C....Yao B.	2018
3	Chronic reactive arthritis associated with prostatitis caused by<i>Neisseria meningitidis</i>. ( 29374652 )	Kawahara K....Morita Y.	2018
4	Management of chronic prostatitis/chronic pelvic pain syndrome. ( 29875042 )	Doiron R.C....Nickel J.C.	2018
5	Involvement of prostatic interstitial cells of Cajal in inflammatory cytokines-elicited catecholamines production: Implications for the pathophysiology of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). ( 29649477 )	Wang J....Wang Q.	2018
6	Injection therapy for chronic prostatitis: A retrospective analysis of 77 cases. ( 29633789 )	Toth A....Zhang J.C.	2018
7	Treatment of refractory category III nonbacterial chronic prostatitis/chronic pelvic pain syndrome with intraprostatic injection of onabotulinumtoxinA: a prospective controlled study. ( 29680006 )	Abdel-Meguid T.A....Abdelsalam A.	2018
8	Computer-Assisted Quantitative Assessment of Prostatic Calcifications in Patients with Chronic Prostatitis. ( 29698941 )	Boltri M....Trinchieri A.	2018
9	Differential research of inflammatory and related mediators in BPH, histological prostatitis and PCa. ( 29441606 )	Huang T.R....Peng B.	2018
10	Letter to the Editor regarding the Article: &quot;Anti-Inflammatory and Antimicrobial Effects of a Novel Herbal Formulation (WSY-1075) in a Chronic Bacterial Prostatitis Rat Model&quot; by Park et al. World J Mens Health 2016;34(3):179-185. ( 29164832 )	Shin Y.S....Park J.K.	2018
11	Acupuncture for chronic prostatitis/chronic pelvic pain syndrome: a randomized, sham acupuncture-controlled trial. ( 29733836 )	Qin Z....Liu Z.	2018
12	Prostatitis, other genitourinary infections and prostate cancer risk: Influence of non-steroidal anti-inflammatory drugs? Results from the EPICAP study. ( 29696626 )	Doat S....Menegaux F.	2018
13	Elevated Adiponectin in Expressed Prostatic Secretion is a Novel Indicator of Inflammatory Prostatitis. ( 29739043 )	Wang Y....Hu H.	2018
14	Oral Fosfomycin for the Treatment of Acute and Chronic Bacterial Prostatitis Caused by Multidrug-Resistant <i>Escherichia coli</i>. ( 29666664 )	Zhanel G.G....Karlowsky J.A.	2018
15	Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome. ( 29757454 )		2018
16	Evaluation of the male with chronic prostatitis/chronic pelvic pain syndrome. ( 29875039 )		2018
17	Psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome: A randomized controlled trial. ( 29862568 )		2018
18	Does a previous prostate biopsy-related acute bacterial prostatitis affect the results of radical prostatectomy? ( 29219284 )		2018
19	Cefoxitin-based antibiotic therapy for ESBL-producing Enterobacteriaceae prostatitis: a prospective pilot-study. ( 29378342 )		2018
20	Do antibiotics decrease prostate-specific antigen levels and reduce the need for prostate biopsy in type IV prostatitis? A systematic literature review. ( 29173276 )		2018
21	Editorial Comment to Psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome: A randomized controlled trial. ( 29962029 )		2018
22	Acupuncture for chronic prostatitis: A systematic review and meta-analysis protocol. ( 29703064 )		2018
23	Quercetin protects against chronic prostatitis in rat model through NF-I_B and MAPK signaling pathways. ( 29654614 )		2018
24	Pharmacodynamic and pharmacokinetic studies and prostatic tissue distribution of fosfomycin tromethamine in bacterial prostatitis or normal rats. ( 29718594 )		2018
25	Acute bacterial prostatitis in an adolescent patient following blunt trauma. ( 29686573 )		2018
26	Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome. ( 29372565 )		2018
27	Prostatitis, a rare presentation of granulomatosis with polyangiitis, successfully treated with rituximab and prednisone. ( 30108118 )	Shaukat MS...Bhatt BD	2018
28	Role of oxidative stress in pathology of chronic prostatitis/chronic pelvic pain syndrome and male infertility and antioxidants function in ameliorating oxidative stress. ( 29990863 )	Ihsan AU...Zhou X	2018
29	Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression. ( 29115491 )	Zeng H...Yang B	2018
30	The evolving clinical picture of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): A look at 1310 patients over 16 years. ( 29485036 )	Doiron RC...Nickel JC	2018
31	Encrusted prostatitis by Corynebacterium urealyticum: The importance of clinical suspicion. ( 29519581 )	Pardo Mart?nez A...Barcel? Bayonas I	2018
32	Expression profile of microRNAs in expressed prostatic secretion of healthy men and patients with IIIA chronic prostatitis/chronic pelvic pain syndrome. ( 29552302 )	Chen Y...Lan T	2018
33	Effect of tadalafil on chronic pelvic pain and prostatic inflammation in a rat model of experimental autoimmune prostatitis. ( 29577372 )	Okamoto K...Oka M	2018
34	Growth hormone-releasing hormone antagonists reduce prostatic enlargement and inflammation in carrageenan-induced chronic prostatitis. ( 29786867 )	Popovics P...Schally AV	2018
35	The distribution of BCG prostatitis: A clue for pathogenetic processes? ( 29987889 )	Butel R...Ball R	2018
36	Neurologic Mechanisms Underlying Voiding Dysfunction due to Prostatitis in a Rat Model of Nonbacterial Prostatic Inflammation. ( 29991230 )	Park JS...Hong CH	2018
37	Phage Therapy in Prostatitis: Recent Prospects. ( 30008710 )	G?rski A...Sfanos KS	2018
38	Chronic pelvic pain and prostate inflammation in rat experimental autoimmune prostatitis: Effect of a single treatment with phosphodiesterase 5 inhibitors on chronic pelvic pain. ( 30009466 )	Kurita M...Oka M	2018
39	Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome: a Cochrane systematic review. ( 30019814 )	Franco JVA...Vietto V	2018
40	Chronic Prostatitis and/or Chronic Pelvic Pain as a Psychoneuromuscular Disorder-A Meta-analysis. ( 30056195 )	Anderson RU...Nathanson BH	2018
41	Semen reactive oxygen species levels are correlated with erectile function among chronic prostatitis/chronic pelvic pain syndrome patients. ( 30068978 )	Alkan I...Ba?ar M	2018
42	Differentially enhancing effects of long-term treatment with Serrazyme, Boswellia and Pine on seminal bacterial detection in patients with chronic bacterial or inflammatory prostatitis, probably related to several degrees of bacterial adherence. ( 30073929 )	Vicari E...Castiglione R	2018
43	Chronic prostatitis developing due to candida infection: A case diagnosed 20 years later and review of up-to-date literature. ( 30105207 )	Demirci A...Turkel S	2018
44	Meta-analysis of the efficacy of Ningmitai capsule on the treatment of chronic prostatitis in China. ( 30113475 )	Jin C...Zhang J	2018
45	Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring. ( 30141123 )	Zhu J...Sun ZY	2018
46	Management of Chronic Prostatitis (CP). ( 30167899 )	Zaidi N...Chughtai B	2018
47	Hypertrophic osteopathy in a castrated dog with prostatic carcinoma and prostatitis. ( 30168146 )	Jennings K...Watts J	2018
48	A combined proof of concept and dose finding study with multiple endpoints: A Bayesian adaptive design in chronic prostatitis/chronic pelvic pain syndrome. ( 30178528 )	Martina R...van Till O	2018
49	Native kidney cytomegalovirus nephritis and cytomegalovirus prostatitis in a kidney transplant recipient. ( 30203504 )	Tan SK...Tan JC	2018
50	Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome. ( 30206001 )	DeWitt-Foy ME...Shoskes DA	2018

Sources

Genes for Prostatitis

Genes related to Prostatitis (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubmedIds
1	KLK3	Kallikrein Related Peptidase 3	Protein Coding	38.19	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	11025702 8854063 9471136 (more) 7519804 15548444 12699471 1372427 19936177 1372426 7518599 15264238 17159365 7686714 10559617 19570492 16209120 12544313 15693428 15638019 12890953 16401916 17318358 17111077 8791046 15241826 15636686 8821701 19548108 16502048 15947609 19725275 15190652 1697014 9687990 7509526 1279213 10799250 1707989 20177031 19111800 18336465 16630522 10604330 7526771 1372788 20224265 15852679 9599634 9126226 9111601 1283895 19524944 18668524 18362491 16800738 16890703 15018076 12913688 11641977 10216506 8750649 1690092 19603556 18836536 18380989 17695414 16882055 14515754 20096883 18595241 17637759 15716187 12962896 10765070 19269787 14770085 11223671 11186419 7533474 9352130 20448364 14624908 15993362 14504750 11225437 7544204
2	VDR	Vitamin D Receptor	Protein Coding	24.63	DISEASES inferred ¹⁵ Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	19269787 17142748 18594491 (more) 17241782
3	MSMB	Microseminoprotein Beta	Protein Coding	24.36	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
4	PROS1	Protein S	Protein Coding	23.72	Novoseek inferred ⁵⁵ GeneCards inferred via : Publications (show sections)	20450358 15389786
5	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	23.24	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
6	IL6	Interleukin 6	Protein Coding	23.23	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
7	NKX3-1	NK3 Homeobox 1	Protein Coding	22.89	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
8	IL1B	Interleukin 1 Beta	Protein Coding	22.84	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
9	TNF	Tumor Necrosis Factor	Protein Coding	22.73	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
10	IL10	Interleukin 10	Protein Coding	22.36	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
11	ADRA1A	Adrenoceptor Alpha 1A	Protein Coding	22.01	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
12	IL2	Interleukin 2	Protein Coding	21.19	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)
13	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	20.96	DISEASES inferred ¹⁵ GeneCards inferred via : Publications (show sections)

Sources

Variations for Prostatitis

Sources

Expression for Prostatitis

Search GEO for disease gene expression data for Prostatitis.

Sources

Pathways for Prostatitis

Pathways related to Prostatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 75)

#	Super pathways	Score	Top Affiliating Genes
1	PEDF Induced Signaling ⁶⁴ Show member pathways all-trans-Retinoic Acid Signaling in Brain ⁶⁴ Cytokine-cytokine receptor interaction ³⁷ Endothelin-1 Signaling Pathway ⁶⁴ Glucocorticoid Receptor Signaling ⁶⁴ IL-6 Pathway ⁶⁴ MIF Mediated Glucocorticoid Regulation ⁶⁴ MIF Regulation of Innate Immune Cells ⁶⁴ NFAT Signaling and Lymphocyte Interactions ⁶⁴ PGC1Alpha Pathway ⁶⁴ RAR-Gamma-RXR-Alpha Degradation ⁶⁴ STAT3 Pathway ⁶⁴	13.63	CXCL8 IL10 IL1B IL2 IL6 TGFB1
2	TGF-Beta Pathway ⁶⁴ Show member pathways JAK-STAT Pathway ⁶⁴ JNK Pathway ⁶⁴ MAPK Family Pathway ⁶⁴ Regulation of eIF4 and p70S6K ⁶⁴ SOCS Pathway ⁶⁴	13.5	CXCL8 IL10 IL1B IL2 IL6 TGFB1
3	Akt Signaling ⁶⁴ Show member pathways p38 Signaling ⁶⁴ Tec Kinases Signaling ⁶⁴	13.39	CXCL8 IL10 IL1B IL2 IL6 TGFB1
4	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	13.34	CXCL8 IL10 IL1B IL2 IL6 TGFB1
5	PAK Pathway ⁶⁴ Show member pathways Antioxidant Action of Vitamin-C ⁶⁴ Epithelial Adherens Junctions ⁶⁴	13.29	CXCL8 IL10 IL1B IL2 IL6 TGFB1
6	Toll-like Receptor Signaling Pathway ³⁷ ¹ Show member pathways Chagas disease (American trypanosomiasis) ³⁷ NOD-like receptor signaling pathway ³⁷ NOD-like Receptor Signaling Pathways ⁶⁵ Regulation of toll-like receptor signaling pathway ¹	13.04	CXCL8 IL10 IL1B IL2 IL6 TGFB1
7	Human cytomegalovirus infection ³⁷ Show member pathways Hepatitis B ³⁷ Human immunodeficiency virus 1 infection ³⁷ Kaposi sarcoma-associated herpesvirus infection ³⁷	13.02	CXCL8 IL1B IL6 TGFB1 TNF
8	Allograft rejection ¹ ³⁷ Show member pathways Antigen processing and presentation ³⁷ Asthma ³⁷ Autoimmune thyroid disease ³⁷ CTL Mediated Apoptosis ⁶⁴ Graft-versus-host disease ³⁷ Intestinal immune network for IgA production ³⁷ THC Differentiation Pathway ⁶⁴ Type I diabetes mellitus ³⁷ Viral myocarditis ³⁷	12.9	CXCL8 IL10 IL1B IL2 IL6 TGFB1
9	Pathways in cancer ³⁷	12.86	CXCL8 IL2 IL6 KLK3 NKX3-1 TGFB1
10	Influenza A ³⁷ Show member pathways Herpes simplex infection ³⁷ Measles ³⁷	12.79	CXCL8 IL1B IL2 IL6 TNF
11	NF-KappaB Family Pathway ⁶⁴ Show member pathways NF-KappaB (p50-p65) Pathway ⁶⁴	12.71	IL1B IL2 IL6 TGFB1 TNF
12	Th17 cell differentiation ³⁷ Show member pathways IL-22 Pathway ⁶⁴ Immune response IL-22 signaling pathway ²² Inflammatory bowel disease (IBD) ³⁷ Th1 and Th2 cell differentiation ³⁷	12.64	IL10 IL1B IL2 IL6 TGFB1 TNF
13	Immune response IL-23 signaling pathway ²² Show member pathways Angiopoietin receptor Tie2-mediated signaling ¹ Angiopoietin-TIE2 Signaling ⁶⁴ Development Angiopoietin - Tie2 signaling ²² Development PDGF signaling via STATs and NF-kB ²² IL23-mediated signaling events ¹ Immune response IL-10 signaling pathway ²² Rac1/Pak1/p38/MMP-2 pathway ¹	12.6	IL10 IL1B IL2 IL6 TNF
14	NF-kappaB Signaling ⁴	12.55	IL10 IL1B IL2 TNF
15	T cell receptor signaling pathway ³⁷ Show member pathways T-Cell antigen Receptor (TCR) Signaling Pathway ¹ T-Cell antigen Receptor (TCR) pathway during Staphylococcus aureus infection ¹	12.47	IL10 IL1B IL2 IL6 TGFB1 TNF
16	Human T-cell leukemia virus 1 infection ³⁷	12.42	IL2 IL6 TGFB1 TNF
17	Selenium Micronutrient Network ¹ Show member pathways Folate Metabolism ¹ Metabolism of ingested MeSeO2H into MeSeH ⁶⁶ thioredoxin pathway ¹ Vitamin B12 Metabolism ¹	12.35	IL1B IL2 IL6 TNF
18	IL-17 Family Signaling Pathways ⁶⁵ Show member pathways IL17 signaling pathway ¹ IL-17 signaling pathway ³⁷ Interleukin-17 signaling ⁶⁶ Mucin expression in CF via IL-6, IL-17 signaling pathways ²²	12.34	CXCL8 IL1B IL6 TNF
19	Toll Comparative Pathway ⁶⁴ Show member pathways IL-1 Pathway ⁶⁴ Immune response MIF in innate immunity response ²² iNOS Signaling ⁶⁴ TLR-TRIF Pathway ⁶⁴	12.31	CXCL8 IL1B IL6 TNF
20	C-type lectin receptor signaling pathway ³⁷ Show member pathways Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways ⁶⁵	12.28	IL10 IL1B IL2 IL6 TNF
21	Immune response IFN alpha/beta signaling pathway ²² Show member pathways Cytokine Network ⁶⁴ Interferon alpha/beta signaling ⁶⁶ Regulation of IFNA signaling ⁶⁶	12.28	CXCL8 IL10 IL1B IL2 IL6 TGFB1
22	Toxoplasmosis ³⁷ Show member pathways Leishmaniasis ³⁷	12.27	IL10 IL1B TGFB1 TNF
23	Tuberculosis ³⁷	12.27	IL10 IL1B IL6 TGFB1 TNF VDR
24	IL-1 Family Signaling Pathways ⁶⁵ Show member pathways Immune response IL-1 signaling pathway ²² Mucin expression in CF via TLRs, EGFR signaling pathways ²²	12.24	CXCL8 IL1B IL6 TNF
25	Bacterial infections in CF airways ²² Show member pathways IL-1 beta-dependent CFTR expression ²² Immune response Bacterial infections in normal airways ²² Immune response TLR signaling pathways ²²	12.21	CXCL8 IL1B IL6 TNF
26	Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways ¹	12.17	CXCL8 IL10 IL1B IL6 NKX3-1 TNF
27	Immune response IFN gamma signaling pathway ²² Show member pathways IFN-gamma pathway ¹	12.12	CXCL8 IL10 IL1B IL2 IL6 TGFB1
28	Transcription Androgen Receptor nuclear signaling ²² Show member pathways Translation Non-genomic (rapid) action of Androgen Receptor ²²	12.09	IL6 KLK3 TGFB1
29	FoxO signaling pathway ³⁷ Show member pathways PLK2 and PLK4 events ¹ Polo-like kinase signaling events in the cell cycle ¹	12.06	IL10 IL6 TGFB1
30	Adipogenesis ¹	12.04	IL6 TGFB1 TNF
31	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁵	12.03	IL10 IL2 IL6 TNF
32	Osteoclast differentiation ³⁷	12.02	IL1B TGFB1 TNF
33	Microglia Activation During Neuroinflammation: Overview ⁶⁵ Show member pathways Microglia Activation During Neuroinflammation: Microglia Activation ⁶⁵	12.02	IL1B IL6 TNF
34	Th1 Differentiation Pathway ⁶⁵ Show member pathways IL27-mediated signaling events ¹ Th17 Differentiation Pathway ⁶⁵	12.02	IL10 IL1B IL2 IL6 TGFB1 TNF
35	Senescence and Autophagy in Cancer ¹	11.99	CXCL8 IL1B IL6 TGFB1
36	AGE-RAGE signaling pathway in diabetic complications ³⁷	11.97	CXCL8 IL1B IL6 TGFB1 TNF
37	Spinal Cord Injury ¹	11.96	CXCL8 IL1B IL2 IL6 TGFB1 TNF
38	TNF signaling pathway ³⁷	11.95	IL1B IL6 TNF
39	Rheumatoid arthritis ³⁷	11.92	CXCL8 IL1B IL6 TGFB1 TNF
40	Interleukin-4 and 13 signaling ⁶⁶	11.9	CXCL8 IL10 IL1B IL6 TGFB1 TNF
41	Hematopoietic cell lineage ³⁷	11.89	IL1B IL6 TNF
42	NF-kappa B signaling pathway ³⁷	11.88	CXCL8 IL1B TNF
43	Corticotropin-releasing hormone signaling pathway ¹	11.87	CXCL8 IL2 TGFB1
44	Cytokine production by Th17 cells in CF (Mouse model) ²² Show member pathways Cytokine production by Th17 cells in CF ²²	11.87	CXCL8 IL6 TGFB1
45	Jak-Stat Signaling Pathway (sino) ⁶⁷	11.86	IL10 IL2 IL6
46	Innate Lymphoid Cell Differentiation Pathways ⁶⁵	11.86	IL10 IL1B IL2 TNF
47	Pertussis ³⁷	11.84	CXCL8 IL10 IL1B IL6 TNF
48	Salmonella infection (KEGG) ³⁷	11.83	CXCL8 IL1B IL6
49	Glucocorticoid receptor regulatory network ¹	11.81	CXCL8 IL2 IL6
50	Amoebiasis ³⁷	11.78	CXCL8 IL10 IL1B IL6 TGFB1 TNF

Sources

GO Terms for Prostatitis

Cellular components related to Prostatitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	extracellular region	GO:0005576	9.65	CXCL8 IL10 IL1B IL2 IL6 KLK3
2	secretory granule	GO:0030141	9.33	IL1B KLK3 TGFB1
3	extracellular space	GO:0005615	9.32	CXCL8 IL10 IL1B IL2 IL6 KLK3

Biological processes related to Prostatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 58)

#	Name	GO ID	Score	Top Affiliating Genes
1	positive regulation of ERK1 and ERK2 cascade	GO:0070374	9.97	ADRA1A IL1B TGFB1 TNF
2	positive regulation of gene expression	GO:0010628	9.97	IL1B IL6 NKX3-1 TGFB1 TNF VDR
3	MAPK cascade	GO:0000165	9.96	IL1B IL2 TGFB1 TNF
4	leukocyte migration	GO:0050900	9.94	IL1B PROS1 TGFB1 TNF
5	inflammatory response	GO:0006954	9.93	CXCL8 IL10 IL1B IL6 TGFB1 TNF
6	positive regulation of NF-kappaB transcription factor activity	GO:0051092	9.89	IL1B IL6 TGFB1 TNF
7	positive regulation of protein phosphorylation	GO:0001934	9.88	IL1B IL2 NKX3-1 TGFB1 TNF
8	response to organic substance	GO:0010033	9.87	IL10 TGFB1 TNF
9	positive regulation of peptidyl-serine phosphorylation	GO:0033138	9.87	IL6 TGFB1 TNF
10	positive regulation of DNA-binding transcription factor activity	GO:0051091	9.86	IL10 IL1B IL6 TNF
11	cellular response to organic cyclic compound	GO:0071407	9.85	IL1B TGFB1 TNF
12	positive regulation of T cell proliferation	GO:0042102	9.83	IL1B IL2 IL6
13	positive regulation of interleukin-6 production	GO:0032755	9.83	IL1B IL6 TNF
14	response to glucocorticoid	GO:0051384	9.81	IL10 IL1B IL6 TNF
15	negative regulation of fat cell differentiation	GO:0045599	9.8	IL6 TGFB1 TNF
16	positive regulation of cell division	GO:0051781	9.8	IL1B NKX3-1 TGFB1
17	cellular response to lipopolysaccharide	GO:0071222	9.8	CXCL8 IL10 IL1B IL6 TNF
18	positive regulation of interferon-gamma production	GO:0032729	9.79	IL1B IL2 TNF
19	lipopolysaccharide-mediated signaling pathway	GO:0031663	9.76	IL1B TGFB1 TNF
20	negative regulation of neurogenesis	GO:0050768	9.74	IL1B IL6 TNF
21	positive regulation of chemokine production	GO:0032722	9.72	IL6 TNF
22	response to vitamin D	GO:0033280	9.72	IL1B TGFB1
23	positive regulation of histone acetylation	GO:0035066	9.72	IL1B TGFB1
24	embryonic digestive tract development	GO:0048566	9.72	CXCL8 TNF
25	negative regulation of lipid catabolic process	GO:0050995	9.72	IL1B TNF
26	regulation of I-kappaB kinase/NF-kappaB signaling	GO:0043122	9.71	IL1B TNF
27	positive regulation of membrane protein ectodomain proteolysis	GO:0051044	9.71	IL1B TNF
28	regulation of regulatory T cell differentiation	GO:0045589	9.71	IL2 TGFB1
29	negative regulation of growth of symbiont in host	GO:0044130	9.71	IL10 TNF
30	positive regulation of interleukin-17 production	GO:0032740	9.71	IL2 TGFB1
31	positive regulation of glial cell proliferation	GO:0060252	9.71	IL1B IL6 TNF
32	positive regulation of immunoglobulin secretion	GO:0051024	9.7	IL2 IL6
33	positive regulation of regulatory T cell differentiation	GO:0045591	9.7	IL2 TGFB1
34	response to molecule of bacterial origin	GO:0002237	9.7	CXCL8 IL10
35	positive regulation of heterotypic cell-cell adhesion	GO:0034116	9.7	IL10 IL1B TNF
36	regulation of signaling receptor activity	GO:0010469	9.7	CXCL8 IL10 IL1B IL2 IL6 TGFB1
37	negative regulation of lipid storage	GO:0010888	9.69	IL6 TNF
38	endothelial cell apoptotic process	GO:0072577	9.68	IL10 TNF
39	positive regulation of chemokine biosynthetic process	GO:0045080	9.68	IL1B TNF
40	regulation of establishment of endothelial barrier	GO:1903140	9.68	IL1B TNF
41	negative regulation of cytokine secretion involved in immune response	GO:0002740	9.67	IL10 TNF
42	epithelial cell proliferation involved in salivary gland morphogenesis	GO:0060664	9.65	NKX3-1 TNF
43	positive regulation of fever generation	GO:0031622	9.65	IL1B TNF
44	chronic inflammatory response to antigenic stimulus	GO:0002439	9.64	IL1B TNF
45	sequestering of triglyceride	GO:0030730	9.63	IL1B TNF
46	protein kinase B signaling	GO:0043491	9.62	IL1B NKX3-1 TGFB1 TNF
47	positive regulation of calcidiol 1-monooxygenase activity	GO:0060559	9.61	IL1B TNF
48	positive regulation of mononuclear cell migration	GO:0071677	9.61	TGFB1 TNF
49	receptor biosynthetic process	GO:0032800	9.6	IL10 TNF
50	negative regulation of mitotic cell cycle	GO:0045930	9.56	IL10 NKX3-1 TGFB1 TNF

Molecular functions related to Prostatitis according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	growth factor activity	GO:0008083	9.26	IL10 IL2 IL6 TGFB1
2	cytokine activity	GO:0005125	9.17	CXCL8 IL10 IL1B IL2 IL6 TGFB1

Sources

Sources for Prostatitis

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ ExPASy

¹⁸ FDA Approved Drugs

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ SNOMED-CT via Orphanet

⁷¹ TGDB

⁷² Tocris

⁷³ UMLS

⁷⁴ UMLS via Orphanet

⁷⁵ UniProtKB/Swiss-Prot

⁷⁶ Wikipedia

Prostatitis

Aliases & Classifications for Prostatitis

MalaCards integrated aliases for Prostatitis:

Classifications:

External Ids:

Summaries for Prostatitis

Related Diseases for Prostatitis

Diseases related to Prostatitis via text searches within MalaCards or GeneCards Suite gene sharing:

Comorbidity relations with Prostatitis via Phenotypic Disease Network (PDN):

Graphical network of the top 20 diseases related to Prostatitis:

Symptoms & Phenotypes for Prostatitis

UMLS symptoms related to Prostatitis:

GenomeRNAi Phenotypes related to Prostatitis according to GeneCards Suite gene sharing:

MGI Mouse Phenotypes related to Prostatitis:

Drugs & Therapeutics for Prostatitis

Drugs for Prostatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

Interventional clinical trials:

Inferred drug relations via UMLS 73 / NDF-RT 51 :

Cochrane evidence based reviews: prostatitis

Genetic Tests for Prostatitis

Anatomical Context for Prostatitis

MalaCards organs/tissues related to Prostatitis:

Publications for Prostatitis

Articles related to Prostatitis:

Genes for Prostatitis

Genes related to Prostatitis (0 elite genes):

Variations for Prostatitis

Expression for Prostatitis

Pathways for Prostatitis

Pathways related to Prostatitis according to GeneCards Suite gene sharing:

GO Terms for Prostatitis

Cellular components related to Prostatitis according to GeneCards Suite gene sharing:

Biological processes related to Prostatitis according to GeneCards Suite gene sharing:

Molecular functions related to Prostatitis according to GeneCards Suite gene sharing:

Sources for Prostatitis

Inferred drug relations via UMLS ⁷³ / NDF-RT ⁵¹ :