Aliases & Classifications for Prostatitis

MalaCards integrated aliases for Prostatitis:

Name: Prostatitis 12 76 55 44 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:14654
ICD10 33 N41 N41.9
ICD9CM 35 601 601.9
MeSH 44 D011472
NCIt 50 C26866
SNOMED-CT 68 9713002
UMLS 73 C0033581

Summaries for Prostatitis

MalaCards based summary : Prostatitis is related to prostate cancer and prostate disease, and has symptoms including prostatism An important gene associated with Prostatitis is KLK3 (Kallikrein Related Peptidase 3), and among its related pathways/superpathways are PEDF Induced Signaling and TGF-Beta Pathway. The drugs Saw palmetto and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include prostate, testes and brain, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 76 Prostatitis is inflammation of the prostate gland. Prostatitis is classified into acute, chronic,... more...

Related Diseases for Prostatitis

Diseases related to Prostatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1163)
# Related Disease Score Top Affiliating Genes
1 prostate cancer 34.5 KLK3 MSMB NKX3-1 PROS1 TGFB1 VDR
2 prostate disease 34.2 KLK3 MSMB NKX3-1
3 prostate sarcoma 34.0 KLK3 NKX3-1
4 nephrogenic adenoma 30.4 KLK3 NKX3-1
5 spinal cord injury 30.3 IL6 TGFB1 TNF
6 osteoarthritis 30.3 IL1B IL6 TGFB1 TNF
7 cystitis 30.2 CXCL8 IL6 TNF
8 alpha-2-macroglobulin deficiency 30.2 KLK3 PROS1
9 breast disease 30.0 KLK3 TGFB1 TNF
10 acute cystitis 30.0 CXCL8 IL6 KLK3
11 anterior uveitis 29.9 IL6 TNF
12 myeloma, multiple 29.9 CXCL8 IL2 IL6 TNF
13 purpura 29.8 IL6 PROS1 TNF
14 osteoporosis 29.7 IL1B IL6 TGFB1 TNF VDR
15 pulmonary tuberculosis 29.7 VDR TNF IL2 IL10
16 bone disease 29.6 IL1B IL6 TNF VDR
17 submandibular gland disease 29.6 KLK3 TGFB1
18 obstructive jaundice 29.6 CXCL8 IL6 TNF
19 microscopic polyangiitis 29.5 IL10 TNF
20 paraneoplastic syndromes 29.5 IL1B IL6
21 schistosomiasis 29.5 IL10 IL2 TNF
22 cardiogenic shock 29.5 IL6 TNF
23 fasciitis 29.5 CXCL8 IL6 TNF
24 arteries, anomalies of 29.4 IL1B IL6 TNF
25 oral tuberculosis 29.4 IL2 TNF
26 acute pyelonephritis 29.3 CXCL8 IL10 IL6
27 end stage renal failure 29.3 IL6 TGFB1 TNF
28 chlamydia 29.3 CXCL8 IL10 IL1B IL6 TNF
29 pulmonary disease, chronic obstructive 29.3 CXCL8 IL6 TGFB1 TNF
30 pouchitis 29.3 CXCL8 IL10
31 paracoccidioidomycosis 29.3 IL10 IL2 IL6 TNF
32 posterior urethral valves 29.3 TNF TGFB1 IL6
33 bacterial sepsis 29.2 CXCL8 IL10 TNF
34 melioidosis 29.2 IL10 IL6 TNF
35 endometriosis 29.2 CXCL8 IL1B IL6
36 localized scleroderma 29.2 IL6 TGFB1 TNF
37 fatty liver disease 29.2 TNF IL6 IL1B CXCL8
38 endocarditis 29.2 TNF IL6 IL10 CXCL8
39 sarcoidosis 1 29.2 IL1B IL2 TNF
40 periodontal disease 29.1 TNF IL6 IL1B CXCL8
41 mycobacterium tuberculosis 1 29.1 IL10 TNF VDR
42 acute pancreatitis 29.1 CXCL8 IL10 IL6
43 tropical spastic paraparesis 29.1 IL10 IL2 IL6
44 necrotizing fasciitis 29.1 IL6 IL2 CXCL8
45 myasthenia gravis 29.0 IL10 IL2 TNF
46 exanthem 29.0 IL2 IL6 TNF
47 pyelonephritis 29.0 CXCL8 IL10 IL1B IL6 TNF
48 chronic fatigue syndrome 29.0 IL10 IL1B IL2 IL6 TGFB1 TNF
49 osteomyelitis 29.0 CXCL8 IL10 IL1B IL6 TNF
50 vaginitis 28.9 IL6 IL1B CXCL8

Comorbidity relations with Prostatitis via Phenotypic Disease Network (PDN):


Acute Cystitis Bladder Neck Obstruction
Chronic Myocardial Ischemia Epididymo-Orchitis
Ischemic Heart Disease Prostate Calculus
Prostate Cancer Prostatic Hypertrophy
Urethral Stricture Urinary Tract Obstruction

Graphical network of the top 20 diseases related to Prostatitis:



Diseases related to Prostatitis

Symptoms & Phenotypes for Prostatitis

UMLS symptoms related to Prostatitis:


prostatism

GenomeRNAi Phenotypes related to Prostatitis according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.77 ADRA1A CXCL8 IL10 IL1B IL2 TGFB1
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.77 ADRA1A CXCL8 IL10 IL1B IL2 TGFB1

MGI Mouse Phenotypes related to Prostatitis:

46 (show all 12)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.16 ADRA1A IL10 IL1B IL2 IL6 PROS1
2 homeostasis/metabolism MP:0005376 10.13 ADRA1A IL10 IL1B IL2 IL6 NKX3-1
3 endocrine/exocrine gland MP:0005379 10.08 IL10 IL2 IL6 MSMB NKX3-1 TGFB1
4 hematopoietic system MP:0005397 10.06 IL10 IL1B IL2 IL6 PROS1 TGFB1
5 digestive/alimentary MP:0005381 10.04 IL10 IL2 IL6 NKX3-1 TGFB1 TNF
6 mortality/aging MP:0010768 10.02 ADRA1A IL10 IL1B IL2 IL6 NKX3-1
7 integument MP:0010771 9.95 IL10 IL1B IL6 PROS1 TGFB1 TNF
8 liver/biliary system MP:0005370 9.85 IL10 IL2 IL6 PROS1 TGFB1 TNF
9 muscle MP:0005369 9.8 ADRA1A IL10 IL6 PROS1 TGFB1 TNF
10 neoplasm MP:0002006 9.76 IL10 IL1B IL2 IL6 MSMB NKX3-1
11 reproductive system MP:0005389 9.56 IL10 IL2 IL6 MSMB NKX3-1 TGFB1
12 skeleton MP:0005390 9.17 IL10 IL1B IL6 NKX3-1 TGFB1 TNF

Drugs & Therapeutics for Prostatitis

Drugs for Prostatitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 155)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Saw palmetto Approved, Experimental, Investigational Phase 4,Phase 3
2
Acetaminophen Approved Phase 4 103-90-2 1983
3
Cycloserine Approved Phase 4,Phase 3 68-41-7 6234 401
4
Testosterone undecanoate Approved, Investigational Phase 4 5949-44-0
5
Testosterone enanthate Approved Phase 4 315-37-7 9416
6
Testosterone Approved, Investigational Phase 4 58-22-0 6013
7
Methyltestosterone Approved Phase 4 58-18-4 6010
8
Acetylcholine Approved Phase 4,Phase 3,Phase 2 51-84-3 187
9
Ciprofloxacin Approved, Investigational Phase 4,Phase 3 85721-33-1 2764
10
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
11
Trimethoprim Approved, Vet_approved Phase 4 738-70-5 5578
12
Sulfamethoxazole Approved Phase 4 723-46-6 5329
13
leucovorin Approved Phase 4 58-05-9 6006 143
14
Amoxicillin Approved, Vet_approved Phase 4 26787-78-0 33613
15
Fosfomycin Approved Phase 4 23155-02-4 446987
16
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
17
gamma-Aminobutyric acid Approved, Investigational Phase 4 56-12-2 119
18
Cilastatin Approved, Investigational Phase 4 82009-34-5 6435415 5280454
19
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
20
Cefoxitin Approved Phase 4 35607-66-0 441199
21
Imipenem Approved Phase 4 74431-23-5, 64221-86-9 104838
22
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4 59-30-3 6037
23
Citric Acid Approved, Nutraceutical, Vet_approved Phase 4 77-92-9 311
24 Prulifloxacin Investigational Phase 4,Phase 2 123447-62-1
25 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2
26 Cholinergic Agents Phase 4,Phase 3,Phase 2,Not Applicable
27 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1
28 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1
29 Psychotropic Drugs Phase 4,Phase 3
30 Anticonvulsants Phase 4,Phase 3
31 Anti-Anxiety Agents Phase 4,Phase 3
32 calcium channel blockers Phase 4,Phase 3
33 Calcium, Dietary Phase 4,Phase 3,Phase 2
34 Analgesics Phase 4,Phase 3,Phase 2
35 Tranquilizing Agents Phase 4,Phase 3
36 Antibiotics, Antitubercular Phase 4,Phase 3,Phase 2
37 Antitubercular Agents Phase 4,Phase 3
38 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
39 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2
40 Acidophilus Phase 4
41 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2
42 Saw palmetto extract Phase 4,Phase 3
43 Fluoroquinolones Phase 4,Phase 3,Phase 2
44 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2
45 Anti-Infective Agents, Urinary Phase 4,Phase 3,Phase 2
46 Renal Agents Phase 4,Phase 3,Phase 2
47 Antimetabolites Phase 4,Phase 3
48 Antineoplastic Agents, Hormonal Phase 4
49 Pharmaceutical Solutions Phase 4,Phase 3
50 Testosterone 17 beta-cypionate Phase 4

Interventional clinical trials:

(show top 50) (show all 86)
# Name Status NCT ID Phase Drugs
1 Treatment of Chronic Bacterial Prostatitis Completed NCT02130713 Phase 4 Third generation fluoroquinolone
2 Treating Urological Chronic Pelvic Pain Syndrome (UCPPS) Pain Completed NCT02385266 Phase 4 D-Cycloserine;Placebo (for D-cycloserine)
3 TRT on BPH Hypoganadal MetS Patients. Florence-PROTEST Completed NCT02366975 Phase 4 Testosterone gel 2%
4 Impact of Six Patient Information Leaflets (PIL) on Doctor Patient Communication Completed NCT02246361 Phase 4
5 Botox as a Treatment for Interstitial Cystitis in Women Completed NCT00194610 Phase 4 Botox
6 Effect of 12 Weeks Treatment With Tadalafil vs Placebo on Lower Urinary Tract Symptoms Recruiting NCT02252367 Phase 4 Tadalafil
7 Cotrimoxazole Prophylaxis in Transurethral Resection or Greenlight Laser Vaporisation of the Prostate Recruiting NCT03633643 Phase 4 oral applications of TMP/SMX 800/160 mg (Nopil forte® tablets);oral applications of Placebo
8 Culture-guided Antimicrobial Prophylaxis in Men Undergoing Prostate Biopsy. Not yet recruiting NCT03228108 Phase 4 Ciprofloxacin;Trimethoprim/Sulfamethoxazole;Fosfomycin;Pivmecillinam/augmentin
9 Effectiveness of Sympathetic Plexus Block on Male Pelvic Pain (Prostatitis, Prostatodynia) Suspended NCT00194636 Phase 4
10 Trial of Viagra' in Men With Chronic Pelvic Pain Syndrome Type III Terminated NCT00194597 Phase 4 Viagra (sildenafil citrate)
11 Botox as a Treatment for Chronic Male Pelvic Pain Syndrome Terminated NCT00194623 Phase 4 Botulinum Toxin A (Botox)
12 Efficacy of Gralise® for Chronic Pelvic Pain Terminated NCT01678911 Phase 4 Gralise
13 Evaluation of the Non-inferiority of Cefoxitin Versus Imipenem/Cilastatin in the Treatment of Urinary Tract Infections Caused by ESBL-producing Escherichia Coli Terminated NCT02474706 Phase 4 Cefoxitin;imipenem
14 Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) Unknown status NCT00371033 Phase 3 Pregabalin;Placebo
15 Efficacy Study of a Standardized Pollen Extract Preparation (Cernilton) to Treat Inflammatory Chronic Prostatitis-Chronic Pelvic Pain Syndrome (CP-CPPS) Completed NCT00919893 Phase 3 Cernilton;Placebo
16 Efficacy Study of Acupuncture to Relieve Symptoms of Chronic Prostatitis Completed NCT00260637 Phase 2, Phase 3
17 An Effectiveness and Safety Study for Levofloxacin in Chronic Prostatitis Completed NCT00402688 Phase 3 levofloxacin;levofloxacin;levofloxacin
18 A Study to Evaluate the Safety and Effectiveness of Levofloxacin Compared With Ciprofloxacin in Patients With Chronic Bacterial Prostatitis Completed NCT00236808 Phase 3 levofloxacin
19 Levofloxacin, Chronic Bacterial Prostatitis Completed NCT00277511 Phase 3 Levofloxacin
20 Trial to Compare Alfuzosin Versus Placebo in the Treatment of Chronic Prostatitis/Chronic Pelvic Pain Syndrome Completed NCT00103402 Phase 3 Alfuzosin
21 Levofloxacin For The Management Of Patients With Abnormal Prostate Specific Antigen (PSA) Completed NCT00169585 Phase 3 Levofloxacin oral tablets
22 Early Antiretroviral Treatment and/or Early Isoniazid Prophylaxis Against Tuberculosis in HIV-infected Adults (ANRS 12136 TEMPRANO) Completed NCT00495651 Phase 3 Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis;Antiretroviral medications;Antiretroviral medications+Isoniazid prophylaxis
23 Complementary and Alternative Medicine for Urological Symptoms(CAMUS) Completed NCT00603304 Phase 3 Saw Palmetto - first 24 weeks;Placebo - first 24 weeks;Saw Palmetto - weeks 24 - 48;Placebo - weeks 24 - 48;Saw Palmetto - weeks 48 - 72;Placebo - weeks 48 - 72
24 "REDUCE" - A Clinical Research Study To Reduce The Incidence Of Prostate Cancer In Men Who Are At Increased Risk Completed NCT00056407 Phase 3 Dutasteride;Placebo
25 Benign Prostatic Hyperplasia Trial With Dutasteride And Tamsulosin Combination Treatment Completed NCT00090103 Phase 3 dutasteride 0.5mg once daily for 4 years;tamsulosin 0.4mg once daily for 4 years
26 Effects of Proxelan Somministration in Patients With Chronic Prostatitis Recruiting NCT03629769 Phase 3 Proxelan
27 JALYN for Benign Prostatic Hyperplasia (BPH) and Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) Terminated NCT01830829 Phase 3 Jalyn;Placebo
28 Botulinum Toxin Type A for the Treatment of Male Chronic Pelvic Pain Syndrome Terminated NCT00464373 Phase 3 Botulinum Toxin Type A;Placebo
29 Efficacy and Tolerability of Delamanid, Linezolid, Pyrazinamide and Levofloxacin Withdrawn NCT02975570 Phase 3 Delamanid;Linezolid;Levofloxacin;Pyrazinamide;WHO MDR-TB regimen
30 Laparoscopic Prostatectomy for Chronic Prostatitis Unknown status NCT00775515 Phase 2
31 Use of Silodosin to Treat Moderate to Severe Abacterial Chronic Prostatitis/Chronic Pelvic Pain Syndrome. Completed NCT00740779 Phase 2 Silodosin 8 mg;Placebo;Silodosin 4 mg
32 An Open-Label Study of CC-10004 for Chronic Prostatitis/Chronic Pelvic Pain Syndrome Completed NCT00701311 Phase 2 CC-10004
33 Botox for Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) Completed NCT00529386 Phase 2 Botox;Lidocaine
34 An Efficacy And Safety Study Of Tanezumab For The Treatment Of Pain Associated With Chronic Abacterial Prostatitis Completed NCT00826514 Phase 2 Tanezumab;Placebo
35 An Effectiveness and Safety Study of ELMIRON (Pentosan Polysulfate Sodium) for the Treatment of Chronic Non-Bacterial Inflammation of the Prostate Gland Completed NCT00236990 Phase 2 pentosan polysulfate sodium
36 A Clinical Study to Investigate the Efficacy, Safety and Pharmacokinetics of ASP3652 in Patients With Chronic Abacterial Prostatitis / Chronic Pelvic Pain Syndrome (CP/CPPS) Completed NCT01391338 Phase 2 ASP3652;Placebo
37 A Pilot Study of Norfloxacin for Hepatopulmonary Syndrome Completed NCT00362752 Phase 2 Norfloxacin;Placebo
38 Intravesical Epirubicin Plus BCG to Prevent the Recurrence of Transitional Cell Carcinoma of Bladder Completed NCT00343356 Phase 2 Trement
39 Safety/Tolerability Study of Alcohol Injection for Treatment of BPH (Enlarged Prostate) Completed NCT00037141 Phase 1, Phase 2 dehydrated alcohol
40 Prulifloxacin in Chronic Bacterial Prostatitis (CBP) Recruiting NCT03201796 Phase 2 Prulifloxacin 600 mg;Levofloxacin 500mg
41 Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy Recruiting NCT02961114 Phase 1, Phase 2
42 Urethral Sterilization With Chlorhexidine Digluconate to Facilitate Primary Repair & Same-Session Implantation Recruiting NCT03614429 Phase 2 Chlorhexidine gel will be prepared according to an international product Instillagel®
43 Open-Label Study of Thalidomide for Chronic Prostatitis/Chronic Pelvic Pain Terminated NCT00301405 Phase 2 Thalidomide
44 Efficacy and Safety of AQX-1125 in Subjects With Chronic Prostatitis/Chronic Pelvic Pain Syndrome Terminated NCT03500159 Phase 2 AQX-1125 200 mg;Placebo
45 Efficacy Study of Tamsulosin and Tolterodine Treatment for Chronic Prostatitis Unknown status NCT00913315 Not Applicable tolterodine;tamsulosin;placebo
46 Efficacy of Acupuncture for Chronic Prostatitis/Chronic Pelvic Pain Syndromes Unknown status NCT02588274 Not Applicable
47 Efficacy of Extracorporal Shock Wave Therapy in Patient With Chronic Non-bacterial Prostatitis / Chronic Pelvic Pain Syndrome Unknown status NCT01714830 Not Applicable
48 Shocking Therapy for Chronic Pelvic Pain Syndrome Unknown status NCT01828996 Not Applicable
49 Effect of Pumpkin Seeds Phonophoresis on Chronic Non-bacterial Prostatitis Completed NCT03461263 Not Applicable
50 Non Interventional Study of Levofloxacin in Chronic Prostatitis Completed NCT02711943 Levofloxacin 500

Search NIH Clinical Center for Prostatitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :


Cochrane evidence based reviews: prostatitis

Genetic Tests for Prostatitis

Anatomical Context for Prostatitis

MalaCards organs/tissues related to Prostatitis:

41
Prostate, Testes, Brain, Spinal Cord, Kidney, Heart, Pituitary

Publications for Prostatitis

Articles related to Prostatitis:

(show top 50) (show all 1128)
# Title Authors Year
1
Effect of Essential Oil on Patients with Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Pilot Randomized Controlled Trial. ( 29948596 )
2018
2
Identification and preliminary study of immunogens involved in autoimmune prostatitis in human males. ( 29947032 )
2018
3
Chronic reactive arthritis associated with prostatitis caused by<i>Neisseria meningitidis</i>. ( 29374652 )
2018
4
Management of chronic prostatitis/chronic pelvic pain syndrome. ( 29875042 )
2018
5
Involvement of prostatic interstitial cells of Cajal in inflammatory cytokines-elicited catecholamines production: Implications for the pathophysiology of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). ( 29649477 )
2018
6
Injection therapy for chronic prostatitis: A retrospective analysis of 77 cases. ( 29633789 )
2018
7
Treatment of refractory category III nonbacterial chronic prostatitis/chronic pelvic pain syndrome with intraprostatic injection of onabotulinumtoxinA: a prospective controlled study. ( 29680006 )
2018
8
Computer-Assisted Quantitative Assessment of Prostatic Calcifications in Patients with Chronic Prostatitis. ( 29698941 )
2018
9
Differential research of inflammatory and related mediators in BPH, histological prostatitis and PCa. ( 29441606 )
2018
10
Letter to the Editor regarding the Article: &amp;quot;Anti-Inflammatory and Antimicrobial Effects of a Novel Herbal Formulation (WSY-1075) in a Chronic Bacterial Prostatitis Rat Model&amp;quot; by Park et al. World J Mens Health 2016;34(3):179-185. ( 29164832 )
2018
11
Acupuncture for chronic prostatitis/chronic pelvic pain syndrome: a randomized, sham acupuncture-controlled trial. ( 29733836 )
2018
12
Prostatitis, other genitourinary infections and prostate cancer risk: Influence of non-steroidal anti-inflammatory drugs? Results from the EPICAP study. ( 29696626 )
2018
13
Elevated Adiponectin in Expressed Prostatic Secretion is a Novel Indicator of Inflammatory Prostatitis. ( 29739043 )
2018
14
Oral Fosfomycin for the Treatment of Acute and Chronic Bacterial Prostatitis Caused by Multidrug-Resistant <i>Escherichia coli</i>. ( 29666664 )
2018
15
Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome. ( 29757454 )
2018
16
Evaluation of the male with chronic prostatitis/chronic pelvic pain syndrome. ( 29875039 )
2018
17
Psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome: A randomized controlled trial. ( 29862568 )
2018
18
Does a previous prostate biopsy-related acute bacterial prostatitis affect the results of radical prostatectomy? ( 29219284 )
2018
19
Cefoxitin-based antibiotic therapy for ESBL-producing Enterobacteriaceae prostatitis: a prospective pilot-study. ( 29378342 )
2018
20
Do antibiotics decrease prostate-specific antigen levels and reduce the need for prostate biopsy in type IV prostatitis? A systematic literature review. ( 29173276 )
2018
21
Editorial Comment to Psychotherapy combined with drug therapy in patients with category III chronic prostatitis/chronic pelvic pain syndrome: A randomized controlled trial. ( 29962029 )
2018
22
Acupuncture for chronic prostatitis: A systematic review and meta-analysis protocol. ( 29703064 )
2018
23
Quercetin protects against chronic prostatitis in rat model through NF-I_B and MAPK signaling pathways. ( 29654614 )
2018
24
Pharmacodynamic and pharmacokinetic studies and prostatic tissue distribution of fosfomycin tromethamine in bacterial prostatitis or normal rats. ( 29718594 )
2018
25
Acute bacterial prostatitis in an adolescent patient following blunt trauma. ( 29686573 )
2018
26
Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome. ( 29372565 )
2018
27
Prostatitis, a rare presentation of granulomatosis with polyangiitis, successfully treated with rituximab and prednisone. ( 30108118 )
2018
28
Role of oxidative stress in pathology of chronic prostatitis/chronic pelvic pain syndrome and male infertility and antioxidants function in ameliorating oxidative stress. ( 29990863 )
2018
29
Resveratrol improves prostate fibrosis during progression of urinary dysfunction in chronic prostatitis by mast cell suppression. ( 29115491 )
2018
30
The evolving clinical picture of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS): A look at 1310 patients over 16 years. ( 29485036 )
2018
31
Encrusted prostatitis by Corynebacterium urealyticum: The importance of clinical suspicion. ( 29519581 )
2018
32
Expression profile of microRNAs in expressed prostatic secretion of healthy men and patients with IIIA chronic prostatitis/chronic pelvic pain syndrome. ( 29552302 )
2018
33
Effect of tadalafil on chronic pelvic pain and prostatic inflammation in a rat model of experimental autoimmune prostatitis. ( 29577372 )
2018
34
Growth hormone-releasing hormone antagonists reduce prostatic enlargement and inflammation in carrageenan-induced chronic prostatitis. ( 29786867 )
2018
35
The distribution of BCG prostatitis: A clue for pathogenetic processes? ( 29987889 )
2018
36
Neurologic Mechanisms Underlying Voiding Dysfunction due to Prostatitis in a Rat Model of Nonbacterial Prostatic Inflammation. ( 29991230 )
2018
37
Phage Therapy in Prostatitis: Recent Prospects. ( 30008710 )
2018
38
Chronic pelvic pain and prostate inflammation in rat experimental autoimmune prostatitis: Effect of a single treatment with phosphodiesterase 5 inhibitors on chronic pelvic pain. ( 30009466 )
2018
39
Non-pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome: a Cochrane systematic review. ( 30019814 )
2018
40
Chronic Prostatitis and/or Chronic Pelvic Pain as a Psychoneuromuscular Disorder-A Meta-analysis. ( 30056195 )
2018
41
Semen reactive oxygen species levels are correlated with erectile function among chronic prostatitis/chronic pelvic pain syndrome patients. ( 30068978 )
2018
42
Differentially enhancing effects of long-term treatment with Serrazyme, Boswellia and Pine on seminal bacterial detection in patients with chronic bacterial or inflammatory prostatitis, probably related to several degrees of bacterial adherence. ( 30073929 )
2018
43
Chronic prostatitis developing due to candida infection: A case diagnosed 20 years later and review of up-to-date literature. ( 30105207 )
2018
44
Meta-analysis of the efficacy of Ningmitai capsule on the treatment of chronic prostatitis in China. ( 30113475 )
2018
45
Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring. ( 30141123 )
2018
46
Management of Chronic Prostatitis (CP). ( 30167899 )
2018
47
Hypertrophic osteopathy in a castrated dog with prostatic carcinoma and prostatitis. ( 30168146 )
2018
48
A combined proof of concept and dose finding study with multiple endpoints: A Bayesian adaptive design in chronic prostatitis/chronic pelvic pain syndrome. ( 30178528 )
2018
49
Native kidney cytomegalovirus nephritis and cytomegalovirus prostatitis in a kidney transplant recipient. ( 30203504 )
2018
50
Management of Chronic Prostatitis/Chronic Pelvic Pain Syndrome. ( 30206001 )
2018

Variations for Prostatitis

Expression for Prostatitis

Search GEO for disease gene expression data for Prostatitis.

Pathways for Prostatitis

Pathways related to Prostatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 75)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.63 CXCL8 IL10 IL1B IL2 IL6 TGFB1
2
Show member pathways
13.5 CXCL8 IL10 IL1B IL2 IL6 TGFB1
3
Show member pathways
13.39 CXCL8 IL10 IL1B IL2 IL6 TGFB1
4
Show member pathways
13.34 CXCL8 IL10 IL1B IL2 IL6 TGFB1
5
Show member pathways
13.29 CXCL8 IL10 IL1B IL2 IL6 TGFB1
6
Show member pathways
13.04 CXCL8 IL10 IL1B IL2 IL6 TGFB1
7
Show member pathways
13.02 CXCL8 IL1B IL6 TGFB1 TNF
8
Show member pathways
12.9 CXCL8 IL10 IL1B IL2 IL6 TGFB1
9 12.86 CXCL8 IL2 IL6 KLK3 NKX3-1 TGFB1
10
Show member pathways
12.79 CXCL8 IL1B IL2 IL6 TNF
11
Show member pathways
12.71 IL1B IL2 IL6 TGFB1 TNF
12
Show member pathways
12.64 IL10 IL1B IL2 IL6 TGFB1 TNF
13
Show member pathways
12.6 IL10 IL1B IL2 IL6 TNF
14 12.55 IL10 IL1B IL2 TNF
15
Show member pathways
12.47 IL10 IL1B IL2 IL6 TGFB1 TNF
16 12.42 IL2 IL6 TGFB1 TNF
17
Show member pathways
12.35 IL1B IL2 IL6 TNF
18
Show member pathways
12.34 CXCL8 IL1B IL6 TNF
19
Show member pathways
12.31 CXCL8 IL1B IL6 TNF
20
Show member pathways
12.28 IL10 IL1B IL2 IL6 TNF
21
Show member pathways
12.28 CXCL8 IL10 IL1B IL2 IL6 TGFB1
22
Show member pathways
12.27 IL10 IL1B TGFB1 TNF
23 12.27 IL10 IL1B IL6 TGFB1 TNF VDR
24
Show member pathways
12.24 CXCL8 IL1B IL6 TNF
25
Show member pathways
12.21 CXCL8 IL1B IL6 TNF
26 12.17 CXCL8 IL10 IL1B IL6 NKX3-1 TNF
27
Show member pathways
12.12 CXCL8 IL10 IL1B IL2 IL6 TGFB1
28
Show member pathways
12.09 IL6 KLK3 TGFB1
29
Show member pathways
12.06 IL10 IL6 TGFB1
30 12.04 IL6 TGFB1 TNF
31 12.03 IL10 IL2 IL6 TNF
32 12.02 IL1B TGFB1 TNF
33
Show member pathways
12.02 IL1B IL6 TNF
34
Show member pathways
12.02 IL10 IL1B IL2 IL6 TGFB1 TNF
35 11.99 CXCL8 IL1B IL6 TGFB1
36 11.97 CXCL8 IL1B IL6 TGFB1 TNF
37 11.96 CXCL8 IL1B IL2 IL6 TGFB1 TNF
38 11.95 IL1B IL6 TNF
39 11.92 CXCL8 IL1B IL6 TGFB1 TNF
40 11.9 CXCL8 IL10 IL1B IL6 TGFB1 TNF
41 11.89 IL1B IL6 TNF
42 11.88 CXCL8 IL1B TNF
43 11.87 CXCL8 IL2 TGFB1
44
Show member pathways
11.87 CXCL8 IL6 TGFB1
45 11.86 IL10 IL2 IL6
46 11.86 IL10 IL1B IL2 TNF
47 11.84 CXCL8 IL10 IL1B IL6 TNF
48 11.83 CXCL8 IL1B IL6
49 11.81 CXCL8 IL2 IL6
50 11.78 CXCL8 IL10 IL1B IL6 TGFB1 TNF

GO Terms for Prostatitis

Cellular components related to Prostatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.65 CXCL8 IL10 IL1B IL2 IL6 KLK3
2 secretory granule GO:0030141 9.33 IL1B KLK3 TGFB1
3 extracellular space GO:0005615 9.32 CXCL8 IL10 IL1B IL2 IL6 KLK3

Biological processes related to Prostatitis according to GeneCards Suite gene sharing:

(show top 50) (show all 58)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.97 ADRA1A IL1B TGFB1 TNF
2 positive regulation of gene expression GO:0010628 9.97 IL1B IL6 NKX3-1 TGFB1 TNF VDR
3 MAPK cascade GO:0000165 9.96 IL1B IL2 TGFB1 TNF
4 leukocyte migration GO:0050900 9.94 IL1B PROS1 TGFB1 TNF
5 inflammatory response GO:0006954 9.93 CXCL8 IL10 IL1B IL6 TGFB1 TNF
6 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.89 IL1B IL6 TGFB1 TNF
7 positive regulation of protein phosphorylation GO:0001934 9.88 IL1B IL2 NKX3-1 TGFB1 TNF
8 response to organic substance GO:0010033 9.87 IL10 TGFB1 TNF
9 positive regulation of peptidyl-serine phosphorylation GO:0033138 9.87 IL6 TGFB1 TNF
10 positive regulation of DNA-binding transcription factor activity GO:0051091 9.86 IL10 IL1B IL6 TNF
11 cellular response to organic cyclic compound GO:0071407 9.85 IL1B TGFB1 TNF
12 positive regulation of T cell proliferation GO:0042102 9.83 IL1B IL2 IL6
13 positive regulation of interleukin-6 production GO:0032755 9.83 IL1B IL6 TNF
14 response to glucocorticoid GO:0051384 9.81 IL10 IL1B IL6 TNF
15 negative regulation of fat cell differentiation GO:0045599 9.8 IL6 TGFB1 TNF
16 positive regulation of cell division GO:0051781 9.8 IL1B NKX3-1 TGFB1
17 cellular response to lipopolysaccharide GO:0071222 9.8 CXCL8 IL10 IL1B IL6 TNF
18 positive regulation of interferon-gamma production GO:0032729 9.79 IL1B IL2 TNF
19 lipopolysaccharide-mediated signaling pathway GO:0031663 9.76 IL1B TGFB1 TNF
20 negative regulation of neurogenesis GO:0050768 9.74 IL1B IL6 TNF
21 positive regulation of chemokine production GO:0032722 9.72 IL6 TNF
22 response to vitamin D GO:0033280 9.72 IL1B TGFB1
23 positive regulation of histone acetylation GO:0035066 9.72 IL1B TGFB1
24 embryonic digestive tract development GO:0048566 9.72 CXCL8 TNF
25 negative regulation of lipid catabolic process GO:0050995 9.72 IL1B TNF
26 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.71 IL1B TNF
27 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.71 IL1B TNF
28 regulation of regulatory T cell differentiation GO:0045589 9.71 IL2 TGFB1
29 negative regulation of growth of symbiont in host GO:0044130 9.71 IL10 TNF
30 positive regulation of interleukin-17 production GO:0032740 9.71 IL2 TGFB1
31 positive regulation of glial cell proliferation GO:0060252 9.71 IL1B IL6 TNF
32 positive regulation of immunoglobulin secretion GO:0051024 9.7 IL2 IL6
33 positive regulation of regulatory T cell differentiation GO:0045591 9.7 IL2 TGFB1
34 response to molecule of bacterial origin GO:0002237 9.7 CXCL8 IL10
35 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.7 IL10 IL1B TNF
36 regulation of signaling receptor activity GO:0010469 9.7 CXCL8 IL10 IL1B IL2 IL6 TGFB1
37 negative regulation of lipid storage GO:0010888 9.69 IL6 TNF
38 endothelial cell apoptotic process GO:0072577 9.68 IL10 TNF
39 positive regulation of chemokine biosynthetic process GO:0045080 9.68 IL1B TNF
40 regulation of establishment of endothelial barrier GO:1903140 9.68 IL1B TNF
41 negative regulation of cytokine secretion involved in immune response GO:0002740 9.67 IL10 TNF
42 epithelial cell proliferation involved in salivary gland morphogenesis GO:0060664 9.65 NKX3-1 TNF
43 positive regulation of fever generation GO:0031622 9.65 IL1B TNF
44 chronic inflammatory response to antigenic stimulus GO:0002439 9.64 IL1B TNF
45 sequestering of triglyceride GO:0030730 9.63 IL1B TNF
46 protein kinase B signaling GO:0043491 9.62 IL1B NKX3-1 TGFB1 TNF
47 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.61 IL1B TNF
48 positive regulation of mononuclear cell migration GO:0071677 9.61 TGFB1 TNF
49 receptor biosynthetic process GO:0032800 9.6 IL10 TNF
50 negative regulation of mitotic cell cycle GO:0045930 9.56 IL10 NKX3-1 TGFB1 TNF

Molecular functions related to Prostatitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 IL10 IL2 IL6 TGFB1
2 cytokine activity GO:0005125 9.17 CXCL8 IL10 IL1B IL2 IL6 TGFB1

Sources for Prostatitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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