MCID: PRT025
MIFTS: 19

Protein-Deficiency Anemia

Categories: Blood diseases, Immune diseases

Aliases & Classifications for Protein-Deficiency Anemia

MalaCards integrated aliases for Protein-Deficiency Anemia:

Name: Protein-Deficiency Anemia 12 15
Anemia Due to Protein Deficiency 12 74

Classifications:



External Ids:

Disease Ontology 12 DOID:13120
ICD9CM 36 281.4
SNOMED-CT 69 85746008
ICD10 34 D53.0
UMLS 74 C0154290

Summaries for Protein-Deficiency Anemia

MalaCards based summary : Protein-Deficiency Anemia, also known as anemia due to protein deficiency, is related to deficiency anemia. An important gene associated with Protein-Deficiency Anemia is GH2 (Growth Hormone 2), and among its related pathways/superpathways are Phospholipase-C Pathway and p70S6K Signaling. Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Protein-Deficiency Anemia

Diseases related to Protein-Deficiency Anemia via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 deficiency anemia 9.8

Comorbidity relations with Protein-Deficiency Anemia via Phenotypic Disease Network (PDN):


Acute Cystitis Deficiency Anemia

Symptoms & Phenotypes for Protein-Deficiency Anemia

GenomeRNAi Phenotypes related to Protein-Deficiency Anemia according to GeneCards Suite gene sharing:

27 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.56 GH1 GH2
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-148 9.56 GH2
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-155 9.56 GH1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-184 9.56 GH2
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-22 9.56 GH2
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-27 9.56 GH2
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-60 9.56 GH1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-101 9.36 GH1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.36 GH1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-130 9.36 GH1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-135 9.36 GH1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-143 9.36 GH2
13 Increased shRNA abundance (Z-score > 2) GR00366-A-151 9.36 GH1 GH2
14 Increased shRNA abundance (Z-score > 2) GR00366-A-161 9.36 GH1
15 Increased shRNA abundance (Z-score > 2) GR00366-A-214 9.36 GH1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-54 9.36 GH1
17 Increased shRNA abundance (Z-score > 2) GR00366-A-96 9.36 GH1

Drugs & Therapeutics for Protein-Deficiency Anemia

Search Clinical Trials , NIH Clinical Center for Protein-Deficiency Anemia

Genetic Tests for Protein-Deficiency Anemia

Anatomical Context for Protein-Deficiency Anemia

Publications for Protein-Deficiency Anemia

Articles related to Protein-Deficiency Anemia:

# Title Authors Year
1
STUDIES ON THE HEMOLYTIC NATURE OF PROTEIN-DEFICIENCY ANEMIA IN THE RAT. ( 14194271 )
1964

Variations for Protein-Deficiency Anemia

Expression for Protein-Deficiency Anemia

Search GEO for disease gene expression data for Protein-Deficiency Anemia.

Pathways for Protein-Deficiency Anemia

Pathways related to Protein-Deficiency Anemia according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.4 GH1 GH2
2
Show member pathways
12.38 GH1 GH2
3
Show member pathways
12.35 GH1 GH2
4
Show member pathways
12.29 GH1 GH2
5
Show member pathways
11.99 GH1 GH2
6
Show member pathways
11.7 GH1 GH2
7
Show member pathways
11.47 GH1 GH2
8
Show member pathways
11.33 GH1 GH2
9
Show member pathways
11.32 GH1 GH2
10 10.85 GH1 GH2
11 10.34 GH1 GH2
12
Show member pathways
10.24 GH1 GH2

GO Terms for Protein-Deficiency Anemia

Cellular components related to Protein-Deficiency Anemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endosome lumen GO:0031904 8.62 GH1 GH2

Biological processes related to Protein-Deficiency Anemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.46 GH1 GH2
2 positive regulation of peptidyl-tyrosine phosphorylation GO:0050731 9.43 GH1 GH2
3 positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 9.4 GH1 GH2
4 response to nutrient levels GO:0031667 9.37 GH1 GH2
5 positive regulation of JAK-STAT cascade GO:0046427 9.32 GH1 GH2
6 animal organ development GO:0048513 9.26 GH1 GH2
7 JAK-STAT cascade involved in growth hormone signaling pathway GO:0060397 9.16 GH1 GH2
8 growth hormone receptor signaling pathway GO:0060396 8.96 GH1 GH2
9 positive regulation of growth GO:0045927 8.62 GH1 GH2

Molecular functions related to Protein-Deficiency Anemia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.16 GH1 GH2
2 hormone activity GO:0005179 8.96 GH1 GH2
3 growth hormone receptor binding GO:0005131 8.62 GH1 GH2

Sources for Protein-Deficiency Anemia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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