MCID: PRT005
MIFTS: 23

Protoplasmic Astrocytoma

Categories: Bone diseases, Cancer diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Protoplasmic Astrocytoma

MalaCards integrated aliases for Protoplasmic Astrocytoma:

Name: Protoplasmic Astrocytoma 12 58 15 70
Protoplasmic Astrocytic Tumor 12
Astrocytoma Protoplasmic 54

Characteristics:

Orphanet epidemiological data:

58
protoplasmic astrocytoma
Inheritance: Not applicable; Age of onset: Childhood;

Classifications:

Orphanet: 58  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:7008
MeSH 44 D001254
NCIt 50 C4320
SNOMED-CT 67 55094006
ICD10 via Orphanet 33 C71.9
UMLS via Orphanet 71 C0334580
Orphanet 58 ORPHA251598
UMLS 70 C0334580

Summaries for Protoplasmic Astrocytoma

MalaCards based summary : Protoplasmic Astrocytoma, also known as protoplasmic astrocytic tumor, is related to diffuse astrocytoma and glioma susceptibility 1, and has symptoms including seizures, headache and motor manifestations. An important gene associated with Protoplasmic Astrocytoma is IDH2 (Isocitrate Dehydrogenase (NADP(+)) 2). Affiliated tissues include brain and eye, and related phenotype is Decreased nuclei size in G2M.

Related Diseases for Protoplasmic Astrocytoma

Diseases related to Protoplasmic Astrocytoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 diffuse astrocytoma 11.4
2 glioma susceptibility 1 10.5
3 malignant astrocytoma 10.5
4 low grade glioma 10.0
5 neurosarcoidosis 10.0
6 low-grade astrocytoma 10.0
7 mixed glioma 9.9 PHLDB1 IDH2
8 multiple enchondromatosis, maffucci type 9.9 PHLDB1 IDH2
9 li-fraumeni syndrome 9.7 PHLDB1 IDH2

Graphical network of the top 20 diseases related to Protoplasmic Astrocytoma:



Diseases related to Protoplasmic Astrocytoma

Symptoms & Phenotypes for Protoplasmic Astrocytoma

UMLS symptoms related to Protoplasmic Astrocytoma:


seizures; headache; motor manifestations; sensory manifestations

GenomeRNAi Phenotypes related to Protoplasmic Astrocytoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased nuclei size in G2M GR00096-A 8.62 FBXO33 PHLDB1

Drugs & Therapeutics for Protoplasmic Astrocytoma

Search Clinical Trials , NIH Clinical Center for Protoplasmic Astrocytoma

Genetic Tests for Protoplasmic Astrocytoma

Anatomical Context for Protoplasmic Astrocytoma

MalaCards organs/tissues related to Protoplasmic Astrocytoma:

40
Brain, Eye

Publications for Protoplasmic Astrocytoma

Articles related to Protoplasmic Astrocytoma:

(show all 29)
# Title Authors PMID Year
1
Cyclooxygenase-2, Bcl-2, and chromosome 1p analysis in protoplasmic astrocytomas. 61 54
15017587 2004
2
Clinicopathological analysis of T2-FLAIR mismatch sign in lower-grade gliomas. 61
32572107 2020
3
[Surgical treatment of protoplasmic astrocytoma of sylvian aqueduct involving posterior part of the third ventricle]. 61
30855596 2019
4
Cerebral astrocytoma in a sheep. 61
29085617 2017
5
Protoplasmic astrocytoma with multifocal involvement: case report and radiological findings. 61
30363198 2015
6
Seizure control after subtotal lesional resection. 61
23724833 2013
7
MR imaging characteristics of protoplasmic astrocytomas. 61
20644924 2011
8
Diffuse central nervous system protoplasmic astrocytoma. 61
20049933 2010
9
[Malignant astrocytoma as a recurrance of astrocytoma II WHO after 13 years. Case report and literature review]. 61
21473001 2010
10
Tumours arising in the setting of paediatric chronic epilepsy. 61
20632818 2010
11
[Muscle atrophy of hand as an initial sign in a patient with protoplasmic astrocytoma: a case report and literature review]. 61
19088841 2008
12
Protoplasmic astrocytoma. A clinicopathologic study of 16 tumors. 61
7785654 1995
13
The applicability of Collins' Law to childhood brain tumors and its usefulness as a predictor of survival. 61
7643986 1995
14
Lobar pilocytic astrocytomas of the cerebral hemispheres: I. Diagnosis and nosology. 61
7851044 1994
15
[Changes in the immunobiochemical composition of the cerebrospinal fluid and the antitumor reactions of the local immune system in astrocytic brain tumors]. 61
7856374 1994
16
[A case of splenial astrocytoma with various neuropsychological symptoms]. 61
8297668 1993
17
Protoplasmic astrocytoma: cytologic features on tissue imprint preparation. 61
1638945 1992
18
Epidemiology of seizures in children with brain tumors. The Childhood Brain Tumor Consortium. 61
1541979 1992
19
[Two autopsied cases of radiation-induced gliosarcoma]. 61
2038421 1991
20
The epidemiology of headache among children with brain tumor. Headache in children with brain tumors. The Childhood Brain Tumor Consortium. 61
2022972 1991
21
Intraobserver reproducibility in assigning brain tumors to classes in the World Health Organization diagnostic scheme. The Childhood Brain Tumor Consortium. 61
2795117 1989
22
[An autopsy case of multicentric glioma of multiple histopathology]. 61
3323931 1987
23
Clinical pathological conference. An unusual cause of a spontaneous intracerebral haematoma. 61
3739617 1986
24
[Schmidt Ruppin-D-ASV-induced primary rat brain tumor model for therapeutic screening]. 61
6291561 1982
25
Concurrence of multiple sclerosis and primary intracranial neoplasms. 61
7260877 1981
26
[Quantitative histological observations in gliomas (author's transl)]. 61
6251667 1980
27
Protoplasmic astrocytoma: an angiographic case report. 61
5544526 1971
28
[Protoplasmic astrocytoma of very slow evolution]. 61
14920801 1951
29
Epilepsy incident to protoplasmic astrocytoma; report of a case. 61
18115670 1949

Variations for Protoplasmic Astrocytoma

Expression for Protoplasmic Astrocytoma

Search GEO for disease gene expression data for Protoplasmic Astrocytoma.

Pathways for Protoplasmic Astrocytoma

GO Terms for Protoplasmic Astrocytoma

Sources for Protoplasmic Astrocytoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....