MCID: PSM001
MIFTS: 29

Psammomatous Meningioma

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Psammomatous Meningioma

MalaCards integrated aliases for Psammomatous Meningioma:

Name: Psammomatous Meningioma 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7210
MeSH 44 D008579
NCIt 50 C4331
SNOMED-CT 68 38431002
UMLS 73 C0334607

Summaries for Psammomatous Meningioma

MalaCards based summary : Psammomatous Meningioma is related to lung meningioma and melanotic neurilemmoma. An important gene associated with Psammomatous Meningioma is ERCC6 (ERCC Excision Repair 6, Chromatin Remodeling Factor), and among its related pathways/superpathways are Blood-Brain Barrier and Immune Cell Transmigration: VCAM-1/CD106 Signaling Pathways and Development EGFR signaling pathway. Affiliated tissues include bone, and related phenotypes are homeostasis/metabolism and immune system

Related Diseases for Psammomatous Meningioma

Diseases related to Psammomatous Meningioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 72)
# Related Disease Score Top Affiliating Genes
1 lung meningioma 10.4 CD34 NF2
2 melanotic neurilemmoma 10.4 CD34 NF2
3 t-cell adult acute lymphocytic leukemia 10.3 CD34 MME
4 plexiform schwannoma 10.3 CD34 NF2
5 breast myofibroblastoma 10.3 CD34 MME
6 atypical neurofibroma 10.3 CD34 NF2
7 invasive malignant thymoma 10.3 CD34 MME
8 breast benign neoplasm 10.2 CD34 MME
9 thoracic benign neoplasm 10.2 CD34 MME
10 clear cell ependymoma 10.2 CD34 NF2
11 cellular schwannoma 10.2 CD34 NF2
12 nephrogenic adenofibroma 10.2 CD34 MME
13 pediatric lymphoma 10.2 CD34 MME
14 peripheral nervous system neoplasm 10.2 CD34 NF2
15 middle ear squamous cell carcinoma 10.1 CD34 MMP9
16 extracranial arteriovenous malformation 10.1 MMP2 MMP9
17 focal myositis 10.1 MMP2 MMP9
18 spastic entropion 10.1 MMP2 MMP9
19 lentigo maligna melanoma 10.1 MMP2 MMP9
20 villous adenocarcinoma 10.1 MMP2 MMP9
21 acute transverse myelitis 10.1 MMP2 MMP9
22 senile ectropion 10.1 MMP2 MMP9
23 ischemic colitis 10.1 MMP2 MMP9
24 parotitis 10.1 MMP2 MMP9
25 light chain deposition disease 10.1 MMP2 MMP9
26 conjunctival nevus 10.1 MMP2 MMP9
27 klatskin's tumor 10.1 MMP2 MMP9
28 microcystic meningioma 10.1 MMP2 MMP9
29 adenomyosis 10.1 MMP2 MMP9
30 corneal ulcer 10.1 MMP2 MMP9
31 nasal cavity squamous cell carcinoma 10.0 MMP2 MMP9
32 odontogenic myxoma 10.0 MMP2 MMP9
33 transverse myelitis 10.0 MMP2 MMP9
34 teratoma 10.0
35 sorsby fundus dystrophy 10.0 MMP2 MMP9
36 lung giant cell carcinoma 10.0 MMP2 MMP9
37 atypical polypoid adenomyoma 10.0 CTNNB1 MME
38 hypertensive heart disease 10.0 MMP2 MMP9
39 aortic aneurysm, familial thoracic 1 9.9 MMP2 MMP9
40 adenomyoma 9.9 CTNNB1 MME
41 tongue cancer 9.9 MMP2 MMP9
42 pneumothorax 9.9 MMP2 MMP9
43 salivary gland cancer 9.9 MMP2 MMP9
44 ossifying fibroma 9.9
45 ovarian germ cell teratoma 9.9
46 aortic disease 9.9 MMP2 MMP9
47 conventional fibrosarcoma 9.9 CD34 CTNNB1
48 nervous system cancer 9.8 CD34 NF2
49 grade iii astrocytoma 9.8 MMP2 MMP9
50 varicose veins 9.8 MMP2 MMP9

Graphical network of the top 20 diseases related to Psammomatous Meningioma:



Diseases related to Psammomatous Meningioma

Symptoms & Phenotypes for Psammomatous Meningioma

MGI Mouse Phenotypes related to Psammomatous Meningioma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.91 CD34 NF2 CTNNB1 ERCC6 MME MMP2
2 immune system MP:0005387 9.87 NF2 CTNNB1 ERCC6 MME MMP2 MMP9
3 integument MP:0010771 9.73 NF2 CTNNB1 ERCC6 MME MMP9 CD34
4 neoplasm MP:0002006 9.63 CTNNB1 ERCC6 MMP2 MMP9 CD34 NF2
5 skeleton MP:0005390 9.35 NF2 CTNNB1 ERCC6 MMP2 MMP9
6 vision/eye MP:0005391 9.02 NF2 CTNNB1 ERCC6 MMP2 MMP9

Drugs & Therapeutics for Psammomatous Meningioma

Search Clinical Trials , NIH Clinical Center for Psammomatous Meningioma

Genetic Tests for Psammomatous Meningioma

Anatomical Context for Psammomatous Meningioma

MalaCards organs/tissues related to Psammomatous Meningioma:

41
Bone

Publications for Psammomatous Meningioma

Articles related to Psammomatous Meningioma:

# Title Authors Year
1
Imaging features of intracranial psammomatous meningioma. ( 28689601 )
2017
2
Dorsal spinal epidural psammomatous meningioma in an adult male. ( 26933358 )
2016
3
A rare component of psammomatous meningioma in a testicular teratoma. ( 24324907 )
2013
4
Rare growth of a psammomatous meningioma in a mature ovarian teratoma: a case report. ( 19616897 )
2010
5
Psammomatoid ossifying fibromas: immunohistochemical analysis and differential diagnosis with psammomatous meningiomas of craniofacial bones. ( 16632273 )
2006
6
Psammomatous meningioma arising from the diaphragma sellae. ( 9638269 )
1998
7
Pathologic quiz case 1. Transitional (psammomatous) meningioma of the ethmoidal sinus. ( 2363928 )
1990

Variations for Psammomatous Meningioma

Expression for Psammomatous Meningioma

Search GEO for disease gene expression data for Psammomatous Meningioma.

Pathways for Psammomatous Meningioma

Pathways related to Psammomatous Meningioma according to GeneCards Suite gene sharing:

(show all 23)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.31 CTNNB1 MMP2 MMP9
2
Show member pathways
12.16 CTNNB1 MMP2 MMP9
3 11.88 CTNNB1 MMP2 MMP9
4 11.76 CTNNB1 MMP2 MMP9
5 11.64 CTNNB1 MMP2 MMP9
6 11.52 CTNNB1 MMP2 MMP9
7 11.48 CD34 MME
8 11.47 CTNNB1 MME
9 11.46 MMP2 MMP9
10 11.41 MMP2 MMP9
11 11.4 MMP2 MMP9
12 11.38 MMP2 MMP9
13
Show member pathways
11.37 MMP2 MMP9
14 11.34 MMP2 MMP9
15 11.3 CTNNB1 MMP9
16 11.25 CD34 MME
17 11.23 CTNNB1 MMP2 MMP9
18 11.19 MMP2 MMP9
19
Show member pathways
11.13 MMP2 MMP9
20 10.99 MMP2 MMP9
21 10.85 MMP2 MMP9
22 10.64 MME MMP2 MMP9
23 10.16 MME MMP2 MMP9

GO Terms for Psammomatous Meningioma

Cellular components related to Psammomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell periphery GO:0071944 8.62 CD34 CTNNB1

Biological processes related to Psammomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hemopoiesis GO:0030097 9.46 CD34 CTNNB1
2 collagen catabolic process GO:0030574 9.43 MMP2 MMP9
3 odontogenesis of dentin-containing tooth GO:0042475 9.4 CTNNB1 NF2
4 negative regulation of neuron death GO:1901215 9.37 CD34 CTNNB1
5 embryo implantation GO:0007566 9.32 MMP2 MMP9
6 positive regulation of vascular smooth muscle cell proliferation GO:1904707 9.26 MMP2 MMP9
7 regulation of neurogenesis GO:0050767 9.16 CTNNB1 NF2
8 endodermal cell differentiation GO:0035987 8.96 MMP2 MMP9
9 ectoderm development GO:0007398 8.62 CTNNB1 NF2

Molecular functions related to Psammomatous Meningioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 metallopeptidase activity GO:0008237 9.13 MME MMP2 MMP9
2 metalloendopeptidase activity GO:0004222 8.8 MME MMP2 MMP9

Sources for Psammomatous Meningioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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