MCID: PSD078
MIFTS: 25

Pseudofolliculitis Barbae

Categories: Genetic diseases, Skin diseases

Aliases & Classifications for Pseudofolliculitis Barbae

MalaCards integrated aliases for Pseudofolliculitis Barbae:

Name: Pseudofolliculitis Barbae 57 37 29 40 73
Pseudofolliculitis Barbae, Susceptibility to 57 13 6
Pili Incarnati 57 73
Ingrown Hairs 57
Pfb 57

Classifications:



External Ids:

OMIM 57 612318
KEGG 37 H00672
ICD10 33 L73.1

Summaries for Pseudofolliculitis Barbae

MalaCards based summary : Pseudofolliculitis Barbae, also known as pseudofolliculitis barbae, susceptibility to, is related to folliculitis and hair whorl. An important gene associated with Pseudofolliculitis Barbae is KRT75 (Keratin 75). The drugs Ornithine and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include skin.

Wikipedia : 76 Pseudofolliculitis barbae (PFB), also known as barber\'s itch, folliculitis barbae traumatica, razor... more...

Description from OMIM: 612318

Related Diseases for Pseudofolliculitis Barbae

Diseases related to Pseudofolliculitis Barbae via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 folliculitis 10.3
2 hair whorl 10.1
3 steatocystoma multiplex 10.1
4 keloids 10.1
5 rosacea 10.1

Graphical network of the top 20 diseases related to Pseudofolliculitis Barbae:



Diseases related to Pseudofolliculitis Barbae

Symptoms & Phenotypes for Pseudofolliculitis Barbae

Clinical features from OMIM:

612318

Drugs & Therapeutics for Pseudofolliculitis Barbae

Drugs for Pseudofolliculitis Barbae (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ornithine Approved, Nutraceutical Phase 2 70-26-8, 3184-13-2 6262
2 Anti-Infective Agents Phase 2
3 Antiparasitic Agents Phase 2
4 Antiprotozoal Agents Phase 2
5
Edetic Acid Approved, Vet_approved Not Applicable 60-00-4, 62-33-9 6049
6
Pentetic acid Approved Not Applicable 67-43-6
7
Petrolatum Approved, Investigational Not Applicable 8009-03-8
8
Polidocanol Approved Not Applicable 9002-92-0

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of 15% Eflornithine Hydrochloride Cream on African-American Males With Pseudofolliculitis Barbae Completed NCT00176995 Phase 2 15% Eflornithine Hdyrochloride
2 Pre-Shave Gel and Brush in Pseudofolliculitis Barbae Completed NCT03043534 Not Applicable
3 Low Fluence 1064nm Laser Hair Reduction for Pseudofolliculitis Barbae in Skin Types IV, V, VI Completed NCT00402129 Not Applicable
4 Interface Kinematics of Transhumeral Prosthetic Sockets Using XROMM Completed NCT01546675 Not Applicable
5 Vacuum Suspension: Effects on Tissue Oxygenation, Activity and Fit Completed NCT00117793 Not Applicable
6 Bioimpedance as a Diagnostic Tool for Assessing the Need for Socket Modification in Transtibial Amputees Recruiting NCT03164356 Not Applicable
7 Shaving Satisfaction in Males With Skin Irritation From Shaving Not yet recruiting NCT03569956 Not Applicable

Search NIH Clinical Center for Pseudofolliculitis Barbae

Genetic Tests for Pseudofolliculitis Barbae

Genetic tests related to Pseudofolliculitis Barbae:

# Genetic test Affiliating Genes
1 Pseudofolliculitis Barbae 29 KRT75

Anatomical Context for Pseudofolliculitis Barbae

MalaCards organs/tissues related to Pseudofolliculitis Barbae:

41
Skin

Publications for Pseudofolliculitis Barbae

Articles related to Pseudofolliculitis Barbae:

(show top 50) (show all 51)
# Title Authors Year
1
<i>Coccidioides immitis</i> soft tissue infection mimicking pseudofolliculitis barbae. ( 29636956 )
2018
2
Barber Knowledge and Recommendations Regarding Pseudofolliculitis Barbae and Acne Keloidalis Nuchae in an Urban Setting. ( 29049485 )
2017
3
Pseudofolliculitis barbae: understanding the condition and the role of facial grooming. ( 27212468 )
2016
4
Folliculitis keloidalis nuchae and pseudofolliculitis barbae: are prevention and effective treatment within reach? ( 24680005 )
2014
5
Pseudofolliculitis Barbae in Females: A Clinical Perspective. ( 25557018 )
2014
6
Shave frequency and regimen variation effects on the management of pseudofolliculitis barbae. ( 23652888 )
2013
7
Successful treatment of recalcitrant folliculitis barbae and pseudofolliculitis barbae with photodynamic therapy. ( 24284123 )
2013
8
Pseudofolliculitis barbae: a dermatoscopic correlate. ( 23785645 )
2013
9
Topical eflornithine hydrochloride improves the effectiveness of standard laser hair removal for treating pseudofolliculitis barbae: a randomized, double-blinded, placebo-controlled trial. ( 22226431 )
2012
10
Pseudofolliculitis barbae induced by oral minoxidil. ( 22607496 )
2012
11
Best practices and evidenced-based use of the 800 nm diode laser for the treatment of pseudofolliculitis barbae in skin of color. ( 22577689 )
2011
12
Low-fluence 1,064-nm laser hair reduction for pseudofolliculitis barbae in skin types IV, V, and VI. ( 19076188 )
2009
13
Comparative evaluation of long pulse Alexandrite laser and intense pulsed light systems for pseudofolliculitis barbae treatment with one year of follow up. ( 20101340 )
2009
14
Pseudofolliculitis barbae. ( 17803606 )
2007
15
Epiluminescence dermatoscopy enhanced patient compliance and achieved treatment success in pseudofolliculitis barbae. ( 16405487 )
2006
16
Modified superlong pulse 810 nm diode laser in the treatment of pseudofolliculitis barbae in skin types V and VI. ( 15841630 )
2005
17
Topical treatment for the inflamed lesion in acne, rosacea, and pseudofolliculitis barbae. ( 15228127 )
2004
18
The medical and surgical therapy of pseudofolliculitis barbae. ( 15113283 )
2004
19
Pseudofolliculitis barbae. ( 15133398 )
2004
20
An unusual Ala12Thr polymorphism in the 1A alpha-helical segment of the companion layer-specific keratin K6hf: evidence for a risk factor in the etiology of the common hair disorder pseudofolliculitis barbae. ( 15086549 )
2004
21
Twice-daily applications of benzoyl peroxide 5%/clindamycin 1% gel versus vehicle in the treatment of pseudofolliculitis barbae. ( 15228130 )
2004
22
Close shave for a keratin disorder-K6hf polymorphism linked to Pseudofolliculitis barbae. ( 15086588 )
2004
23
Pseudofolliculitis barbae and acne keloidalis nuchae. ( 14717405 )
2003
24
Treatment of pseudofolliculitis barbae using the long-pulse Nd:YAG laser on skin types V and VI. ( 14725660 )
2003
25
Pseudofolliculitis barbae: review and update on new treatment modalities. ( 12901468 )
2003
26
Treatment of pseudofolliculitis barbae in very dark skin with a long pulse Nd:YAG laser. ( 12408693 )
2002
27
Treatment of pseudofolliculitis barbae in skin types IV, V, and VI with a long-pulsed neodymium:yttrium aluminum garnet laser. ( 12140474 )
2002
28
Defining pseudofolliculitis barbae in 2001: a review of the literature and current trends. ( 11807473 )
2002
29
Treatment of pseudofolliculitis barbae using the Q-switched Nd:YAG laser with topical carbon suspension. ( 10940059 )
2000
30
Lasers in treatment of Pseudofolliculitis barbae. ( 10950573 )
1999
31
Treatment of pseudofolliculitis barbae with the diode laser. ( 11357287 )
1999
32
An Aftershave Lotion for Pseudofolliculitis Barbae. ( 23985551 )
1999
33
The causes and treatment of pseudofolliculitis barbae. ( 9640558 )
1998
34
Hyperplastic pseudofolliculitis barbae associated with cyclosporin. ( 9039313 )
1997
35
Management of pseudofolliculitis barbae. ( 7659218 )
1995
36
Pseudofolliculitis barbae associated with an unusual hair whorl. ( 8453890 )
1993
37
Treatment of pseudofolliculitis barbae with topical glycolic acid: a report of two studies. ( 8261811 )
1993
38
Scar sarcoidosis in pseudofolliculitis barbae. ( 1922852 )
1991
39
Pseudofolliculitis barbae. ( 2587496 )
1989
40
Pseudofolliculitis barbae and related disorders. ( 3048823 )
1988
41
Pseudofolliculitis barbae. ( 3046269 )
1988
42
Treatment of steatocystoma multiplex and pseudofolliculitis barbae with isotretinoin. ( 3475194 )
1987
43
Pseudofolliculitis barbae with keloids. ( 3540094 )
1986
44
A Pseudofolliculitis Barbae clinic for the black male who has to shave. ( 6530503 )
1984
45
Pathogenesis and treatment of pseudofolliculitis barbae. ( 6354618 )
1983
46
Evaluation of a foil-guarded shaver in the management of pseudofolliculitis barbae. ( 7238107 )
1981
47
Pseudofolliculitis barbae. Medical consequences of interracial friction in the US Army. ( 759123 )
1979
48
Pseudofolliculitis barbae. No 'pseudoproblem'. ( 758495 )
1979
49
Pseudofolliculitis barbae in a woman. ( 736598 )
1978
50
Pseudofolliculitis barbae. 2. Treatment. ( 892961 )
1977

Variations for Pseudofolliculitis Barbae

ClinVar genetic disease variations for Pseudofolliculitis Barbae:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 KRT75 NM_004693.2(KRT75): c.481G> A (p.Ala161Thr) single nucleotide variant risk factor rs2232387 GRCh37 Chromosome 12, 52827608: 52827608
2 KRT75 NM_004693.2(KRT75): c.481G> A (p.Ala161Thr) single nucleotide variant risk factor rs2232387 GRCh38 Chromosome 12, 52433824: 52433824

Expression for Pseudofolliculitis Barbae

Search GEO for disease gene expression data for Pseudofolliculitis Barbae.

Pathways for Pseudofolliculitis Barbae

GO Terms for Pseudofolliculitis Barbae

Sources for Pseudofolliculitis Barbae

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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