MCID: PSD004
MIFTS: 27

Pseudomembranous Conjunctivitis

Categories: Neuronal diseases

Aliases & Classifications for Pseudomembranous Conjunctivitis

MalaCards integrated aliases for Pseudomembranous Conjunctivitis:

Name: Pseudomembranous Conjunctivitis 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:11190
ICD9CM 34 372.04
NCIt 50 C35196
SNOMED-CT 67 267643002
ICD10 32 H10.22
UMLS 70 C0155144

Summaries for Pseudomembranous Conjunctivitis

Disease Ontology : 12 A acute conjunctivitis which involves a fibrin-rich exudate formation on the surface of the conjunctiva. Infectious causes of pseudomembranes include Corynebacterium diphtheriae, streptococci, pneumococci, herpes simplex virus, adenovirus, Chlamydia and gonococci. Other causes include chemical (alkali) irritants, erythema multiforme, and ocular pemphigoid.

MalaCards based summary : Pseudomembranous Conjunctivitis is related to conjunctivitis and chlamydia. An important gene associated with Pseudomembranous Conjunctivitis is PLG (Plasminogen), and among its related pathways/superpathways are Developmental Biology and Keratinization. Affiliated tissues include bone marrow, eye and bone, and related phenotype is integument.

Related Diseases for Pseudomembranous Conjunctivitis

Diseases related to Pseudomembranous Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 57)
# Related Disease Score Top Affiliating Genes
1 conjunctivitis 10.6
2 chlamydia 10.1
3 alpha-2-plasmin inhibitor deficiency 10.1 SERPING1 PLG
4 pemphigus erythematosus 10.0 DSP DSG3
5 bronchiolitis obliterans 10.0 PPL EVPL
6 keratitis, hereditary 10.0
7 lipoid proteinosis of urbach and wiethe 10.0
8 yemenite deaf-blind hypopigmentation syndrome 10.0
9 branchiootic syndrome 1 10.0
10 graft-versus-host disease 10.0
11 hand, foot and mouth disease 10.0
12 acute hemorrhagic conjunctivitis 10.0
13 keratopathy 10.0
14 mouth disease 10.0
15 filamentary keratitis 10.0
16 acute graft versus host disease 10.0
17 ligneous conjunctivitis 10.0
18 stevens-johnson syndrome/toxic epidermal necrolysis 10.0
19 darier-white disease 9.9 DSP DSG3
20 angioedema, hereditary, type i 9.9 SERPING1 PLG
21 castleman disease 9.9 PPL DSG3
22 pemphigus vegetans 9.9 PPL DSG1
23 erythroderma, congenital, with palmoplantar keratoderma, hypotrichosis, and hyper-ige 9.9 DSP DSG1
24 striate palmoplantar keratoderma 9.9 DSP DSG1
25 thymoma 9.9 PPL EVPL DSP
26 diffuse palmoplantar keratoderma 9.9 DSP DSG1
27 cardiomyopathy, dilated, with woolly hair and keratoderma 9.8 DSP DSG1
28 palmoplantar keratoderma, nonepidermolytic 9.8 DSP DSG1
29 pachyonychia congenita 1 9.8 DSP DSG1
30 herpetiform pemphigus 9.8 DSG3 DSG1
31 tinea imbricata 9.8 DSG3 DSG1
32 palmoplantar keratosis 9.8 DSP DSG1
33 bullous impetigo 9.8 DSG3 DSG1
34 impetigo 9.8 DSG3 DSG1
35 pemphigoid gestationis 9.7 DSG3 DSG1
36 hereditary angioedema 9.7 SERPING1 PLG
37 pyoderma 9.7 DSG3 DSG1
38 autoimmune disease of skin and connective tissue 9.7 DSG3 DSG1
39 hair disease 9.7 DSP DSG1
40 palmoplantar keratoderma, epidermolytic 9.7 EVPL DSP DSG1
41 lichen disease 9.6 PPL DSG3 DSG1
42 ritter's disease 9.6 DSP DSG3 DSG1
43 follicular dendritic cell sarcoma 9.6 PPL EVPL DSP DSG3
44 naxos disease 9.6 DSP DSG3 DSG1
45 benign chronic pemphigus 9.6 DSP DSG3 DSG1
46 lichen planus 9.5 DSG3 DSG1
47 integumentary system disease 9.5 SERPING1 DSG3 DSG1
48 familial woolly hair syndrome 9.4 PPL DSP DSG3 DSG1
49 iga pemphigus 9.4 PPL EVPL DSG3 DSG1
50 pemphigus foliaceus 9.4 PPL EVPL DSG3 DSG1

Graphical network of the top 20 diseases related to Pseudomembranous Conjunctivitis:



Diseases related to Pseudomembranous Conjunctivitis

Symptoms & Phenotypes for Pseudomembranous Conjunctivitis

MGI Mouse Phenotypes related to Pseudomembranous Conjunctivitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.17 DSG1 DSG3 DSP EVPL LAMA3 PLG

Drugs & Therapeutics for Pseudomembranous Conjunctivitis

Search Clinical Trials , NIH Clinical Center for Pseudomembranous Conjunctivitis

Genetic Tests for Pseudomembranous Conjunctivitis

Anatomical Context for Pseudomembranous Conjunctivitis

MalaCards organs/tissues related to Pseudomembranous Conjunctivitis:

40
Bone Marrow, Eye, Bone

Publications for Pseudomembranous Conjunctivitis

Articles related to Pseudomembranous Conjunctivitis:

(show all 42)
# Title Authors PMID Year
1
Pseudomembranous conjunctivitis with hand, foot and mouth disease in a pregnant woman : a case report. 61
33653308 2021
2
Haemorrhagic conjunctivitis with pseudomembranous related to SARS-CoV-2. 61
32377594 2020
3
Epidemiology of pseudomembranous conjunctivitis in a tertiary hospital: A 2-year retrospective study. 61
32907398 2020
4
Haemolacria: a case of pseudomembranous conjunctivitis in a neonate. 61
32606124 2020
5
Bristle Worm-Induced Keratouveitis: A Case Report. 61
31842040 2020
6
Pseudomembranous Conjunctivitis: A Possible Conjunctival Foreign Body Aetiology. 61
32566417 2020
7
[Ligneous conjunctivitis: A diagnosis to consider in the case of a lingering pseudomembranous conjunctivitis!] 61
31262596 2019
8
An interesting case of factitious pseudomembranous conjunctivitis. 61
31546512 2019
9
Pseudomembranous conjunctivitis: unveil the curtain. 61
30878958 2019
10
Ligneous conjunctivitis in a Dandy-Walker syndrome: A rare case report. 61
30574926 2019
11
Plasmapheresis, Intravenous Immunoglobulins, and Autologous Serum Eyedrops in the Acute Eye Complications of Toxic Epidermal Necrolysis. 61
28362052 2017
12
Ocular exposure to paraquat resulting in keratopathy, pseudomembranous conjunctivitis and symblepharon. 61
28571054 2017
13
External ophthalmomyiasis: a case series and review of ophthalmomyiasis in Turkey. 61
26895273 2016
14
Cicatrizing Conjunctivitis in a Patient Diagnosed With Drug Reaction With Eosinophilia and Systemic Symptoms/Drug-Induced Hypersensitivity Syndrome but With Features of Stevens-Johnson Syndrome. 61
27078005 2016
15
Rare extrapulmonary complications of Mycoplasma pneumoniae infection. 61
26837942 2016
16
Conjunctival Acute Graft-versus-Host Disease in Adult Patients Receiving Allogeneic Hematopoietic Stem Cell Transplantation: A Cohort Study. 61
27902756 2016
17
Visual acuity and anterior segment findings in chronic graft-versus-host disease. 61
21996943 2011
18
Topical ophthalmic cyclosporine in the treatment of toxic epidermal necrolysis. 61
22242029 2011
19
Successful treatment of Stevens-Johnson syndrome with steroid pulse therapy at disease onset. 61
19285657 2009
20
Ocular complications in a child with acute graft-versus-host disease following cord blood stem cell transplantation: therapeutic challenges. 61
16879579 2006
21
[Ligneous conjunctivitis: complication of inborn plasminogen deficiency (a case report)]. 61
15782857 2005
22
Ocular manifestations of graft versus host disease. 61
15523196 2004
23
Ligneous conjunctivitis, hydrocephalus, hydrocele, and pulmonary involvement in a child with homozygous type I plasminogen deficiency. 61
12719968 2003
24
Paraneoplastic pemphigus associated with uterine carcinoma. 61
12734481 2003
25
[Corneal complications after hematopoietic stem cell transplantation]. 61
12640552 2003
26
[Ligneous conjunctivitis in a patient with plasminogen type I deficiency--case report with review of literature]. 61
11987044 2002
27
Ocular findings in allogeneic stem cell transplantation without total body irradiation. 61
10406617 1999
28
Ligneous conjunctivitis in plasminogen-deficient mice. 61
9473227 1998
29
Pseudomembranous conjunctivitis following topical gentamicin therapy. 61
9400798 1997
30
Homozygous mutations in the plasminogen gene of two unrelated girls with ligneous conjunctivitis. 61
9242524 1997
31
Homozygous type I plasminogen deficiency. 61
9255907 1997
32
Pseudomembranous conjunctivitis following bone marrow transplantation: immunopathological and ultrastructural study of one case. 61
8600048 1996
33
Ligneous (pseudomembranous) inflammation of the female genital tract. A report of two cases. 61
8320683 1993
34
Pseudomembranous and membranous conjunctivitis. Immunohistochemical features. 61
1384271 1992
35
[Epidemic keratoconjunctivitis: treatment results during an epidemic]. 61
1701507 1990
36
Lipoid proteinosis with pseudomembranous conjunctivitis. 61
3950140 1986
37
The eye in bone marrow transplantation. I. Clinical study. 61
6340648 1983
38
[3 cases of pseudomembranous conjunctivitis]. 61
755573 1978
39
Ocular manifestations of toxic epidermal necrolysis associated with allopurinol use. 61
889509 1977
40
[Familial pseudomembranous conjunctivitis]. 61
13146060 1954
41
[Chronic pseudomembranous conjunctivitis]. 61
14859312 1951
42
Recurrent Pseudomembranous Conjunctivitis. 61
21007797 1945

Variations for Pseudomembranous Conjunctivitis

Expression for Pseudomembranous Conjunctivitis

Search GEO for disease gene expression data for Pseudomembranous Conjunctivitis.

Pathways for Pseudomembranous Conjunctivitis

Pathways related to Pseudomembranous Conjunctivitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.93 PPL EVPL DSP DSG3 DSG1
2
Show member pathways
11.48 PPL EVPL DSP DSG3 DSG1
3
Show member pathways
11.4 DSP DSG3 DSG1
4 11.19 PLG LAMA3
5
Show member pathways
11.17 PPL EVPL DSP
6 11.06 SERPING1 PLG
7 10.75 PLG LAMA3

GO Terms for Pseudomembranous Conjunctivitis

Cellular components related to Pseudomembranous Conjunctivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.7 SERPING1 PPL PLG LAMA3 EVPL DSP
2 cell junction GO:0030054 9.65 PPL EVPL DSP DSG3 DSG1
3 collagen-containing extracellular matrix GO:0062023 9.61 SERPING1 PLG LAMA3
4 intermediate filament GO:0005882 9.54 PPL EVPL DSP
5 cell-cell junction GO:0005911 9.5 DSP DSG3 DSG1
6 platelet alpha granule lumen GO:0031093 9.46 SERPING1 PLG
7 ficolin-1-rich granule membrane GO:0101003 9.4 DSP DSG1
8 cornified envelope GO:0001533 9.35 PPL EVPL DSP DSG3 DSG1
9 desmosome GO:0030057 9.02 PPL EVPL DSP DSG3 DSG1

Biological processes related to Pseudomembranous Conjunctivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell adhesion GO:0098609 9.56 LAMA3 DSP DSG3 DSG1
2 epidermis development GO:0008544 9.54 LAMA3 EVPL DSP
3 wound healing GO:0042060 9.5 PPL EVPL DSP
4 keratinocyte differentiation GO:0030216 9.48 EVPL DSP
5 hemostasis GO:0007599 9.46 SERPING1 PLG
6 peptide cross-linking GO:0018149 9.43 EVPL DSP
7 fibrinolysis GO:0042730 9.4 SERPING1 PLG
8 keratinization GO:0031424 9.35 PPL EVPL DSP DSG3 DSG1
9 intermediate filament cytoskeleton organization GO:0045104 9.33 PPL EVPL DSP
10 cornification GO:0070268 9.02 PPL EVPL DSP DSG3 DSG1

Molecular functions related to Pseudomembranous Conjunctivitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 8.92 PPL LAMA3 EVPL DSP

Sources for Pseudomembranous Conjunctivitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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