PSORS10
MCID: PSR031
MIFTS: 24

Psoriasis 10 (PSORS10)

Categories: Genetic diseases, Immune diseases, Rare diseases, Skin diseases

Aliases & Classifications for Psoriasis 10

MalaCards integrated aliases for Psoriasis 10:

Name: Psoriasis 10 57 12 15
Psoriasis Susceptibility 10 57 13
Psors10 57 12
Psoriasis 10, Susceptibility to 57

Classifications:



External Ids:

Disease Ontology 12 DOID:0111289
OMIM® 57 612410
OMIM Phenotypic Series 57 PS177900

Summaries for Psoriasis 10

Disease Ontology : 12 A psoriasis that has material basis in variation in a region on chromosome 18p11.23.

MalaCards based summary : Psoriasis 10, also known as psoriasis susceptibility 10, is related to psoriasis and psoriatic arthritis. An important gene associated with Psoriasis 10 is PSORS10 (Psoriasis Susceptibility 10), and among its related pathways/superpathways is Keratinization. Affiliated tissues include skin.

More information from OMIM: 612410 PS177900

Related Diseases for Psoriasis 10

Graphical network of the top 20 diseases related to Psoriasis 10:



Diseases related to Psoriasis 10

Symptoms & Phenotypes for Psoriasis 10

Clinical features from OMIM®:

612410 (Updated 05-Apr-2021)

Drugs & Therapeutics for Psoriasis 10

Search Clinical Trials , NIH Clinical Center for Psoriasis 10

Genetic Tests for Psoriasis 10

Anatomical Context for Psoriasis 10

MalaCards organs/tissues related to Psoriasis 10:

40
Skin

Publications for Psoriasis 10

Articles related to Psoriasis 10:

(show all 29)
# Title Authors PMID Year
1
Psoriasis susceptibility locus on 18p revealed by genome scan in Finnish families not associated with PSORS1. 57
14632189 2003
2
Effect of immunosuppressive drugs in immune-mediated inflammatory disease during the coronavirus pandemic. 61
32829511 2020
3
Teledermatologic monitoring for chronic cutaneous autoimmune diseases with smartworking during COVID-19 emergency in a tertiary center in Italy. 61
32458588 2020
4
Nonvenereal Penile Dermatoses: A Retrospective Study. 61
29644193 2018
5
Expression of Janus Kinase 1 in vitiligo & psoriasis before and after narrow band UVB: a case-control study. 61
29127481 2018
6
Sustained Psoriasis Area and Severity Index, Dermatology Life Quality Index and EuroQol-5D response of biological treatment in psoriasis: 10 years of real-world data in the Swedish National Psoriasis Register. 61
28644904 2018
7
Rethinking costs of psoriasis: 10% of patients account for nearly 40% of healthcare expenditures among enrollees with psoriasis in a U.S. health plan. 61
28320213 2017
8
Gene Expression Analysis of Inflammatory Cytokines in Korean Psoriatic Patients. 61
28761289 2017
9
Improvement in Extensive Moderate Plaque Psoriasis With a Novel Emollient Spray Formulation of Betamethasone Dipropionate 0.05. 61
26954319 2016
10
Metabolomics in psoriatic disease: pilot study reveals metabolite differences in psoriasis and psoriatic arthritis. 61
25580230 2014
11
Management and evaluation of extra-articular manifestations in spondyloarthritis. 61
23227118 2012
12
Development of psoriasis 10 years after allogeneic hematopoietic cell transplantation from non-psoriatic donor: Further evidences for genetics and immunopathogenesis of psoriasis. 61
22671141 2012
13
Serum levels of the regulatory cytokines transforming growth factor-β and interleukin-10 are reduced in patients with discoid lupus erythematosus. 61
21372199 2011
14
Lipid profile in patients with psoriasis presenting at Liaquat University Hospital Hyderabad. 61
19757693 2009
15
[Investigation of tinea pedis and toenail onychomycosis prevalence in patients with psoriasis]. 61
19795619 2009
16
Serum leptin levels, skin leptin and leptin receptor expression in psoriasis. 61
18637894 2008
17
Evaluation of survivin and NF-kappaB in psoriasis, an immunohistochemical study. 61
18005174 2008
18
Prevalence and correlates of suicidal ideation among patients with skin disease. 61
16488292 2006
19
Inpatient dermatology: characteristics of patients and admissions in a Spanish hospital. 61
12224688 2002
20
[Role of bile acids and endotoxins in the pathogenesis and therapy of psoriasis]. 61
10827473 2000
21
Induction of cutaneous lymphocyte-associated antigen expression by group A streptococcal antigens in psoriasis. 61
9452887 1997
22
Detection of human papillomavirus DNA in keratoacanthomas by polymerase chain reaction. 61
9056648 1997
23
Evaluation of circulating immune complexes in cutaneous diseases associated with immune disorders. 61
2143349 1990
24
Tin-protoporphyrin and long wave length ultraviolet light in treatment of psoriasis. 61
2566782 1989
25
Cardiovascular disease, cancer, and cause of death in patients with psoriasis: 10 years prospective experience in a cohort of 1,380 patients. 61
3411140 1988
26
The pharmacokinetics of selenium in psoriasis and atopic dermatitis. 61
2461029 1988
27
Subpopulations of T lymphocytes in psoriasis patients and their changes during immunotherapy. 61
2963042 1987
28
Preliminary report on the therapeutic effect of khellin in psoriasis. 61
6628802 1983
29
[Zumbusch type pustular psoriasis (10 years of observation)]. 61
5964917 1966

Variations for Psoriasis 10

Expression for Psoriasis 10

Search GEO for disease gene expression data for Psoriasis 10.

Pathways for Psoriasis 10

Pathways related to Psoriasis 10 according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.25 LCE3D LCE3C LCE3A

GO Terms for Psoriasis 10

Biological processes related to Psoriasis 10 according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 defense response to Gram-positive bacterium GO:0050830 9.32 LCE3C LCE3A
2 defense response to Gram-negative bacterium GO:0050829 9.26 LCE3C LCE3A
3 killing of cells of other organism GO:0031640 9.16 LCE3C LCE3A
4 keratinization GO:0031424 9.13 LCE3D LCE3C LCE3A
5 epidermis development GO:0008544 8.8 LCE3D LCE3C LCE3A

Sources for Psoriasis 10

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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