MCID: PSR018
MIFTS: 37

Psoriasis 13

Categories: Genetic diseases, Skin diseases, Rare diseases

Aliases & Classifications for Psoriasis 13

MalaCards integrated aliases for Psoriasis 13:

Name: Psoriasis 13 57 75
Psoriasis Susceptibility 13 57 29 13 6
Psoriasis Vulgaris 75 73
Psoriasis 75 73
Psors13 57 75
Psoriasis, Susceptibility to, Type 13 40
Psoriasis 13, Susceptibility to 57
Pv 75

Classifications:



External Ids:

OMIM 57 614070
MedGen 42 C3279754
MeSH 44 D011565
UMLS 73 C0263361

Summaries for Psoriasis 13

UniProtKB/Swiss-Prot : 75 Psoriasis 13: A common, chronic inflammatory disease of the skin with multifactorial etiology. It is characterized by red, scaly plaques usually found on the scalp, elbows and knees. These lesions are caused by abnormal keratinocyte proliferation and infiltration of inflammatory cells into the dermis and epidermis.

MalaCards based summary : Psoriasis 13, also known as psoriasis susceptibility 13, is related to psoriasis and polycythemia vera, and has symptoms including exanthema, pruritus and psoriasiform rash. An important gene associated with Psoriasis 13 is TRAF3IP2 (TRAF3 Interacting Protein 2). Affiliated tissues include skin, t cells and liver.

Description from OMIM: 614070

Related Diseases for Psoriasis 13

Graphical network of the top 20 diseases related to Psoriasis 13:



Diseases related to Psoriasis 13

Symptoms & Phenotypes for Psoriasis 13

Clinical features from OMIM:

614070

UMLS symptoms related to Psoriasis 13:


exanthema, pruritus, psoriasiform rash

Genetic Tests for Psoriasis 13

Genetic tests related to Psoriasis 13:

# Genetic test Affiliating Genes
1 Psoriasis Susceptibility 13 29 TRAF3IP2

Anatomical Context for Psoriasis 13

MalaCards organs/tissues related to Psoriasis 13:

41
Skin, T Cells, Liver, Thyroid, Neutrophil, Tongue, Pituitary

Publications for Psoriasis 13

Articles related to Psoriasis 13:

(show top 50) (show all 296)
# Title Authors Year
1
Psoriasis vulgaris in a patient with pemphigus vulgaris on corticosteroid therapy. ( 29689136 )
2018
2
Relationship between etanercept and thyroid function in patients with psoriasis vulgaris. ( 29440950 )
2018
3
Auftreten einer Psoriasis vulgaris bei einem Patienten mit Pemphigus vulgaris unter Kortikosteroidtherapie. ( 29750447 )
2018
4
Relapsing polychondritis associated with psoriasis vulgaris successfully treated with adalimumab: A case report with published work review. ( 28266051 )
2017
5
Adult-onset Still's disease in a patient with psoriasis vulgaris showing inverse correlation of disease activity. ( 29083047 )
2017
6
The association of genetic variants in chemokine genes with the risk of psoriasis vulgaris in Chinese population: A case-control study. ( 29145242 )
2017
7
[The positive relationship between survivin and STAT2 up-expressed in skin lesions of psoriasis vulgaris]. ( 29089085 )
2017
8
Natural killer cells from psoriasis vulgaris patients have reduced levels of cytotoxicity associated degranulation and cytokine production. ( 26477484 )
2017
9
Tumor necrosis factor alpha gene promoter -238G/A polymorphism increases the risk of psoriasis vulgaris in Indian patients. ( 28093730 )
2017
10
Methods report: European S3-Guideline on the systemic treatment of psoriasis vulgaris - Update Apremilast and Secukinumab - EDF in cooperation with EADV and IPC. ( 28944515 )
2017
11
The Investigation of Antimicrobial Peptides Expression and Its Related Interaction with Methotrexate Treatment in Patients with Psoriasis Vulgaris. ( 28067065 )
2017
12
MicroRNA138 regulates keratin 17 protein expression to affect HaCaT cell proliferation and apoptosis by targeting hTERT in psoriasis vulgaris. ( 27936398 )
2017
13
MiR-200a expression in CD4+ T cells correlates with the expression of Th17/Treg cells and relevant cytokines in psoriasis vulgaris: A case control study. ( 28738533 )
2017
14
Is Ki-67, keratin 16, involucrin, and filaggrin immunostaining sufficient to diagnose inflammatory linear verrucous epidermal nevus? A report of eight cases and a comparison with psoriasis vulgaris. ( 29166506 )
2017
15
Bullous pemphigoid with IgG autoantibodies to the I+3 subunit of laminin 332 associated with psoriasis vulgaris. ( 28468743 )
2017
16
Cyr61/CCN1 is involved in the pathogenesis of psoriasis vulgaris via promoting IL-8 production by keratinocytes in a JNK/NF-I_B pathway. ( 27856305 )
2017
17
Lack of association between CARD10/CARMA3 tag SNPs and psoriasis vulgaris in the southern Chinese population. ( 28301668 )
2017
18
Pityriasis Lichenoides et Varioliformis Acuta and Psoriasis Vulgaris: Mere Coincidence or a Rare Association? ( 28218230 )
2017
19
The development of chronic inflammatory demyelinating polyneuropathy during adalimumab treatment in a patient with psoriasis vulgaris. ( 27086491 )
2016
20
Altered Circulating T Follicular Helper Cell Subsets in Patients with Psoriasis Vulgaris. ( 27662792 )
2016
21
Recurrence of Psoriasis Vulgaris Accompanied by Treatment with C-C Chemokine Receptor Type 4 (CCR4) Antibody (Mogamulizumab) Therapies in a Patient with Adult T cell Leukemia/ Lymphoma: Insight into Autoinflammatory Diseases. ( 27181545 )
2016
22
CARD14 gene polymorphism c.C2458T (p.Arg820Trp) is associated with clinical features of psoriasis vulgaris in a Chinese cohort. ( 26249641 )
2016
23
Variants of CARD14 gene and psoriasis vulgaris in southern Chinese cohort. ( 26982778 )
2016
24
Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris. ( 27152848 )
2016
25
A Genetic Variant rs1020760at NFKB1 is Associated with Clinical Features of Psoriasis Vulgaris in a Han Chinese Population. ( 27346731 )
2016
26
Novel inflammatory markers in psoriasis vulgaris: vaspin, vascular adhesion protein-1 (VAP-1), and YKL-40. ( 25279492 )
2016
27
The -2518 A/G MCP-1 and -403 G/A RANTES promoter gene polymorphisms are associated with psoriasis vulgaris. ( 27859608 )
2016
28
Serum levels of TWEAK in patients with psoriasis vulgaris. ( 26499979 )
2016
29
TLR2 and TLR4 polymorphisms in Southern Chinese Psoriasis Vulgaris patients. ( 27155792 )
2016
30
Colocalization of linear lichen planus and psoriasis vulgaris. ( 27730052 )
2016
31
Low vitamin D-modulated calcium-regulating proteins in psoriasis vulgaris plaques: S100A7 overexpression depends on joint involvement. ( 27573000 )
2016
32
A Case of Severe Panuveitis Associated with Psoriasis Vulgaris Successfully Treated with Infliximab. ( 27239187 )
2016
33
Serum Preptin and Amylin Values in Psoriasis Vulgaris and BehAset's Patients. ( 25545917 )
2016
34
The Spectrum of Mild to Severe Psoriasis Vulgaris Is Defined by a Common Activation of IL-17 Pathway Genes, butA with Key Differences in Immune Regulatory Genes. ( 27185339 )
2016
35
Correction: Based on Molecular Profiling of Gene Expression, Palmoplantar Pustulosis and Palmoplantar Pustular Psoriasis Are Highly Related Diseases that Appear to Be Distinct from Psoriasis Vulgaris. ( 27326461 )
2016
36
Association between atopic dermatitis-related single nucleotide polymorphisms rs4722404 and psoriasis vulgaris in a southern Chinese cohort. ( 27421022 )
2016
37
[Verrucous variant of porokeratosis of Mibelli as a differential diagnosis of psoriasis vulgaris]. ( 26525967 )
2016
38
Association analysis of psoriasis vulgaris and psoriatic arthritis with loss-of-function mutations in IL36RN in German patients. ( 27038307 )
2016
39
A genetic coding variant rs72474224 in GJB2 is associated with clinical features of psoriasis vulgaris in a Chinese Han population. ( 26104599 )
2015
40
Epidermolysis bullosa acquisita in a patient with psoriasis vulgaris. ( 26243636 )
2015
41
The role of CGRP and CALCA T-692C single-nucleotide polymorphism in psoriasis vulgaris. ( 25997247 )
2015
42
Anti-laminin-gamma 1 Pemphigoid with Generalized Pustular Psoriasis and Psoriasis Vulgaris. ( 26074471 )
2015
43
Association of angiopoietin-1, angiopoietin-2 and caspase-5 polymorphisms with psoriasis vulgaris. ( 25753570 )
2015
44
Circulating levels of inflammatory cytokines in patients with psoriasis vulgaris of different Chinese medicine syndromes. ( 25523599 )
2015
45
Exacerbation of psoriasis vulgaris during nivolumab for oral mucosal melanoma. ( 26388113 )
2015
46
Cetuximab and panitumumab in a patient with colon cancer and concomitant chronic skin disease: A potential beneficial effect on psoriasis vulgaris. ( 25834345 )
2015
47
Progranulin is preferentially expressed in patients with psoriasis vulgaris and protects mice from psoriasis-like skin inflammation. ( 25626394 )
2015
48
Activating CARD14 Mutations Are Associated with Generalized Pustular Psoriasis but Rarely Account for Familial Recurrence in Psoriasis Vulgaris. ( 26203641 )
2015
49
MMP-9 gene polymorphisms (rs3918242, rs3918254 and rs4810482) and the risk of psoriasis vulgaris: No evidence for associations in a Chinese Han population. ( 26554609 )
2015
50
The TNFAIP3 polymorphism rs610604 both associates with the risk of psoriasis vulgaris and affects the clinical severity. ( 25496073 )
2015

Variations for Psoriasis 13

UniProtKB/Swiss-Prot genetic disease variations for Psoriasis 13:

75
# Symbol AA change Variation ID SNP ID
1 TRAF3IP2 p.Asp19Asn VAR_047349 rs33980500

Expression for Psoriasis 13

Search GEO for disease gene expression data for Psoriasis 13.

Pathways for Psoriasis 13

GO Terms for Psoriasis 13

Sources for Psoriasis 13

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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