PSORS6
MCID: PSR027
MIFTS: 21

Psoriasis 6 (PSORS6)

Categories: Genetic diseases, Immune diseases, Rare diseases, Skin diseases

Aliases & Classifications for Psoriasis 6

MalaCards integrated aliases for Psoriasis 6:

Name: Psoriasis 6 56 12
Psoriasis Susceptibility 6 56 13
Psors6 56 12
Psoriasis 6, Susceptibility to 56

Classifications:



External Ids:

Disease Ontology 12 DOID:0111290
OMIM 56 605364
OMIM Phenotypic Series 56 PS177900

Summaries for Psoriasis 6

Disease Ontology : 12 A psoriasis that has material basis in variation in a region on chromosome 19p13 that includes BSG.

MalaCards based summary : Psoriasis 6, also known as psoriasis susceptibility 6, is related to psoriasis 1 and skin disease. An important gene associated with Psoriasis 6 is PSORS6 (Psoriasis Susceptibility 6). The drugs Paclitaxel and Indirubin have been mentioned in the context of this disorder. Affiliated tissues include skin and tonsil.

More information from OMIM: 605364 PS177900

Related Diseases for Psoriasis 6

Diseases in the Psoriasis family:

Psoriasis 1 Psoriasis 3
Psoriasis 2 Psoriasis 4
Psoriasis 5 Psoriasis 6
Psoriasis 7 Psoriasis 9
Psoriasis 8 Psoriasis 10
Psoriasis 11 Psoriasis 12
Psoriasis 13 Psoriasis 15

Diseases related to Psoriasis 6 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 psoriasis 1 10.2
2 skin disease 10.2
3 pustulosis of palm and sole 10.0
4 psoriasis 10.0
5 pustular psoriasis 9.7

Graphical network of the top 20 diseases related to Psoriasis 6:



Diseases related to Psoriasis 6

Symptoms & Phenotypes for Psoriasis 6

Clinical features from OMIM:

605364

Drugs & Therapeutics for Psoriasis 6

Drugs for Psoriasis 6 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
2
Indirubin Investigational Phase 2 479-41-4
3 Anti-Bacterial Agents Phase 2
4 Antibiotics, Antitubercular Phase 2
5 Albumin-Bound Paclitaxel Phase 2
6 Antimitotic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Mechanistic Study of Indigo Naturalis in Treating Psoriasis: Local or Systemic Manipulation of Inflammation and Induction of Immunoregulation Completed NCT02088281 Phase 2 Indigo naturalis extract in oil ointment
2 A Pilot Open-Label Single-Dose Study Using Intravenous Micellar Paclitaxel for Patients With Severe Psoriasis Completed NCT00006276 Phase 2 Micellar Paclitaxel

Search NIH Clinical Center for Psoriasis 6

Genetic Tests for Psoriasis 6

Anatomical Context for Psoriasis 6

MalaCards organs/tissues related to Psoriasis 6:

40
Skin, Tonsil

Publications for Psoriasis 6

Articles related to Psoriasis 6:

(show all 33)
# Title Authors PMID Year
1
Characterisation of psoriasis susceptibility locus 6 (PSORS6) in patients with early onset psoriasis and evidence for interaction with PSORS1. 61 56
19525279 2009
2
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. 61 56
16163348 2005
3
A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in central south Chinese population. 56
21655935 2011
4
Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13. 56
10986047 2000
5
Serlopitant for Psoriatic Pruritus: a Phase 2 Randomized, Double-Blind, Placebo-Controlled Clinical Trial. 61
32007513 2020
6
Group A Streptococcal Vulvitis in Adult Women: Clinical Features and Association With Psoriasis. 61
31592977 2019
7
US real-world effectiveness of secukinumab for the treatment of psoriasis: 6-month analysis from the Corrona Psoriasis Registry. 61
31035822 2019
8
Low Dose Naltrexone in Dermatology 61
30909326 2019
9
What is psoriasis? - Perception and assessment of psoriasis among the German population. 61
29873901 2018
10
Psoriasis, chronic tonsillitis, and biofilms: Tonsillar pathologic findings supporting a microbial hypothesis. 61
29554401 2018
11
Comprehensive Assessment of the Psoriasis Patient (CAPP): A Report from the GRAPPA 2015 Annual Meeting. 61
27134270 2016
12
Ipilimumab Therapy in Patients With Advanced Melanoma and Preexisting Autoimmune Disorders. 61
26633184 2016
13
Spondyloarthropathy in inflammatory bowel disease patients on TNF inhibitors. 61
26337851 2015
14
Re: Complete Clinical Remission of Psoriasis 6 Months After Renal Transplantation. 61
26293100 2015
15
Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis. 61
26613086 2015
16
Complete clinical remission of psoriasis 6 months after renal transplantation. 61
24034050 2013
17
A retrospective analysis of real-life practice of off-label photodynamic therapy using methyl aminolevulinate (MAL-PDT) in 20 Italian dermatology departments. Part 1: inflammatory and aesthetic indications. 61
22949035 2013
18
The south-east Scotland dermatology workload study: 30 years' analysis. 61
22372993 2012
19
Safety of anti-tumour necrosis factor agents in patients with chronic hepatitis C infection: a systematic review. 61
21690185 2011
20
Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes. 61
20054338 2010
21
Psoriatic arthritis in Asia. 61
19713440 2009
22
Infliximab for the treatment of severe pustular psoriasis: 6 years later. 61
18341534 2008
23
Disseminated nontuberculous mycobacterial infection in patients who are not infected with HIV in Thailand. 61
17638188 2007
24
Plasmacytoid dendritic cells are absent in skin lesions of polymorphic light eruption. 61
17254032 2007
25
Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. 61
17052659 2006
26
[Bullous pemphigoid in young patients: a retrospective study of 74 cases]. 61
15798559 2005
27
Association scan of the novel psoriasis susceptibility region on chromosome 19: evidence for both susceptible and protective loci. 61
12930307 2003
28
The sternoclavicular syndrome: experience from a district general hospital and results of a national postal survey. 61
11257153 2001
29
The treatment of psoriasis with etretinate and acitretin: a follow up of actual use. 61
11056421 2000
30
A randomized comparison of narrow-band TL-01 phototherapy and PUVA photochemotherapy for psoriasis. 61
10534635 1999
31
Azathioprine in dermatological practice. An overview with special emphasis on its use in non-bullous inflammatory dermatoses. 61
10599368 1999
32
Supervised four-week heliotherapy alleviates the long-term course of psoriasis. 61
7904411 1993
33
Mast cells in the initial stages of psoriasis. 61
3233011 1988

Variations for Psoriasis 6

Expression for Psoriasis 6

Search GEO for disease gene expression data for Psoriasis 6.

Pathways for Psoriasis 6

GO Terms for Psoriasis 6

Sources for Psoriasis 6

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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