PSORS6
MCID: PSR027
MIFTS: 22

Psoriasis 6 (PSORS6)

Categories: Genetic diseases, Immune diseases, Rare diseases, Skin diseases

Aliases & Classifications for Psoriasis 6

MalaCards integrated aliases for Psoriasis 6:

Name: Psoriasis 6 57 12
Psoriasis Susceptibility 6 57 13
Psors6 57 12
Psoriasis 6, Susceptibility to 57

Classifications:



External Ids:

Disease Ontology 12 DOID:0111290

Summaries for Psoriasis 6

Disease Ontology : 12 A psoriasis that has material basis in variation in a region on chromosome 19p13 that includes BSG.

MalaCards based summary : Psoriasis 6, also known as psoriasis susceptibility 6, is related to psoriasis 1 and skin disease. An important gene associated with Psoriasis 6 is PSORS6 (Psoriasis Susceptibility 6). The drugs Paclitaxel and Indirubin have been mentioned in the context of this disorder. Affiliated tissues include skin and tonsil.

More information from OMIM: 605364 PS177900

Related Diseases for Psoriasis 6

Diseases in the Psoriasis family:

Psoriasis 1 Psoriasis 3
Psoriasis 2 Psoriasis 4
Psoriasis 5 Psoriasis 6
Psoriasis 7 Psoriasis 9
Psoriasis 8 Psoriasis 10
Psoriasis 11 Psoriasis 12
Psoriasis 13 Psoriasis 15

Diseases related to Psoriasis 6 via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 psoriasis 1 10.2
2 skin disease 10.2
3 pustulosis of palm and sole 10.0
4 psoriasis 10.0
5 pustular psoriasis 9.7

Graphical network of the top 20 diseases related to Psoriasis 6:



Diseases related to Psoriasis 6

Symptoms & Phenotypes for Psoriasis 6

Clinical features from OMIM:

605364

Drugs & Therapeutics for Psoriasis 6

Drugs for Psoriasis 6 (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
2 Indirubin Investigational Phase 2 479-41-4
3 Anti-Bacterial Agents Phase 2
4 Antibiotics, Antitubercular Phase 2
5 Antineoplastic Agents, Phytogenic Phase 2
6 Tubulin Modulators Phase 2
7 Albumin-Bound Paclitaxel Phase 2
8 Antimitotic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Mechanistic Study of Indigo Naturalis in Treating Psoriasis: Local or Systemic Manipulation of Inflammation and Induction of Immunoregulation Completed NCT02088281 Phase 2 Indigo naturalis extract in oil ointment
2 A Pilot Open-Label Single-Dose Study Using Intravenous Micellar Paclitaxel for Patients With Severe Psoriasis Completed NCT00006276 Phase 2 Micellar Paclitaxel

Search NIH Clinical Center for Psoriasis 6

Genetic Tests for Psoriasis 6

Anatomical Context for Psoriasis 6

MalaCards organs/tissues related to Psoriasis 6:

41
Skin, Tonsil

Publications for Psoriasis 6

Articles related to Psoriasis 6:

(show all 31)
# Title Authors PMID Year
1
Characterisation of psoriasis susceptibility locus 6 (PSORS6) in patients with early onset psoriasis and evidence for interaction with PSORS1. 38 8
19525279 2009
2
Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins. 38 8
16163348 2005
3
A miRNA-492 binding-site polymorphism in BSG (basigin) confers risk to psoriasis in central south Chinese population. 8
21655935 2011
4
Genomewide scan in german families reveals evidence for a novel psoriasis-susceptibility locus on chromosome 19p13. 8
10986047 2000
5
US real-world effectiveness of secukinumab for the treatment of psoriasis: 6-month analysis from the Corrona Psoriasis Registry. 38
31035822 2019
6
Low Dose Naltrexone in Dermatology 38
30909326 2019
7
What is psoriasis? - Perception and assessment of psoriasis among the German population. 38
29873901 2018
8
Psoriasis, chronic tonsillitis, and biofilms: Tonsillar pathologic findings supporting a microbial hypothesis. 38
29554401 2018
9
Comprehensive Assessment of the Psoriasis Patient (CAPP): A Report from the GRAPPA 2015 Annual Meeting. 38
27134270 2016
10
Ipilimumab Therapy in Patients With Advanced Melanoma and Preexisting Autoimmune Disorders. 38
26633184 2016
11
Spondyloarthropathy in inflammatory bowel disease patients on TNF inhibitors. 38
26337851 2015
12
Re: Complete Clinical Remission of Psoriasis 6 Months After Renal Transplantation. 38
26293100 2015
13
Polymorphisms Associated with Age at Onset in Patients with Moderate-to-Severe Plaque Psoriasis. 38
26613086 2015
14
Complete clinical remission of psoriasis 6 months after renal transplantation. 38
24034050 2013
15
A retrospective analysis of real-life practice of off-label photodynamic therapy using methyl aminolevulinate (MAL-PDT) in 20 Italian dermatology departments. Part 1: inflammatory and aesthetic indications. 38
22949035 2013
16
The south-east Scotland dermatology workload study: 30 years' analysis. 38
22372993 2012
17
Safety of anti-tumour necrosis factor agents in patients with chronic hepatitis C infection: a systematic review. 38
21690185 2011
18
Regulation of the psoriatic chemokine CCL20 by E3 ligases Trim32 and Piasy in keratinocytes. 38
20054338 2010
19
Psoriatic arthritis in Asia. 38
19713440 2009
20
Infliximab for the treatment of severe pustular psoriasis: 6 years later. 38
18341534 2008
21
Disseminated nontuberculous mycobacterial infection in patients who are not infected with HIV in Thailand. 38
17638188 2007
22
Plasmacytoid dendritic cells are absent in skin lesions of polymorphic light eruption. 38
17254032 2007
23
Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. 38
17052659 2006
24
[Bullous pemphigoid in young patients: a retrospective study of 74 cases]. 38
15798559 2005
25
Association scan of the novel psoriasis susceptibility region on chromosome 19: evidence for both susceptible and protective loci. 38
12930307 2003
26
The sternoclavicular syndrome: experience from a district general hospital and results of a national postal survey. 38
11257153 2001
27
The treatment of psoriasis with etretinate and acitretin: a follow up of actual use. 38
11056421 2000
28
A randomized comparison of narrow-band TL-01 phototherapy and PUVA photochemotherapy for psoriasis. 38
10534635 1999
29
Azathioprine in dermatological practice. An overview with special emphasis on its use in non-bullous inflammatory dermatoses. 38
10599368 1999
30
Supervised four-week heliotherapy alleviates the long-term course of psoriasis. 38
7904411 1993
31
Mast cells in the initial stages of psoriasis. 38
3233011 1988

Variations for Psoriasis 6

Expression for Psoriasis 6

Search GEO for disease gene expression data for Psoriasis 6.

Pathways for Psoriasis 6

GO Terms for Psoriasis 6

Sources for Psoriasis 6

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
Content
Loading form....