PSORS8
MCID: PSR030
MIFTS: 22

Psoriasis 8 (PSORS8)

Categories: Genetic diseases, Immune diseases, Rare diseases, Skin diseases

Aliases & Classifications for Psoriasis 8

MalaCards integrated aliases for Psoriasis 8:

Name: Psoriasis 8 56 12 15
Psoriasis Susceptibility 8 56 13
Psors8 56 12
Psoriasis 8, Susceptibility to 56

Classifications:



External Ids:

Disease Ontology 12 DOID:0111288
OMIM 56 610707
OMIM Phenotypic Series 56 PS177900

Summaries for Psoriasis 8

Disease Ontology : 12 A psoriasis that has material basis in variation in a region on chromosome 16q. This region overlaps one that is associated with inflammatory bowel disease 1 disease.

MalaCards based summary : Psoriasis 8, also known as psoriasis susceptibility 8, is related to psoriasis and psoriasis 4. An important gene associated with Psoriasis 8 is PSORS8 (Psoriasis Susceptibility 8). Affiliated tissues include skin, colon and monocytes.

More information from OMIM: 610707 PS177900

Related Diseases for Psoriasis 8

Graphical network of the top 20 diseases related to Psoriasis 8:



Diseases related to Psoriasis 8

Symptoms & Phenotypes for Psoriasis 8

Clinical features from OMIM:

610707

Drugs & Therapeutics for Psoriasis 8

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase 2 Dose Ranging, Evaluator-Blinded Study to Evaluate the Safety of Topical IDP-118 Unknown status NCT01670513 Phase 1, Phase 2 IDP-118 Low Strength;IDP-118 High Strength

Search NIH Clinical Center for Psoriasis 8

Genetic Tests for Psoriasis 8

Anatomical Context for Psoriasis 8

MalaCards organs/tissues related to Psoriasis 8:

40
Skin, Colon, Monocytes

Publications for Psoriasis 8

Articles related to Psoriasis 8:

(show all 19)
# Title Authors PMID Year
1
The International Psoriasis Genetics Study: assessing linkage to 14 candidate susceptibility loci in a cohort of 942 affected sib pairs. 56
12851855 2003
2
A Crohn's disease-associated insertion polymorphism (3020insC) in the NOD2 gene is not associated with psoriasis vulgaris, palmo-plantar pustular psoriasis or guttate psoriasis. 56
12930309 2003
3
Exclusion of CARD15/NOD2 as a candidate susceptibility gene to psoriasis in the Italian population. 56
12459523 2002
4
Lack of association between NOD2 3020InsC frameshift mutation and psoriasis. 56
11886540 2001
5
Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan. 56
9259283 1997
6
Treatment Persistence and Safety of Apremilast in Psoriasis: Experience With 30 Patients in Routine Clinical Practice. 61
32423533 2020
7
The active compounds derived from Psoralea corylifolia for photochemotherapy against psoriasis-like lesions: The relationship between structure and percutaneous absorption. 61
30153523 2018
8
Treatment with TNF-α inhibitor rectifies M1 macrophage polarization from blood CD14+ monocytes in patients with psoriasis independent of STAT1 and IRF-1 activation. 61
29914850 2018
9
Trial Characteristics as Contextual Factors When Evaluating Targeted Therapies in Patients With Psoriatic Disease: A Meta-Epidemiologic Study. 61
29073353 2018
10
8-methoxypsoralen reduces AKT phosphorylation, induces intrinsic and extrinsic apoptotic pathways, and suppresses cell growth of SK-N-AS neuroblastoma and SW620 metastatic colon cancer cells. 61
28627461 2017
11
Quality of life impact of childhood skin conditions measured using the Children's Dermatology Life Quality Index (CDLQI): a meta-analysis. 61
26686685 2016
12
Matrix metalloproteinase-2 promoter variability in psoriasis. 61
19360430 2009
13
Alefacept modifies long-term disease severity and improves the response to other treatments. 61
16172047 2005
14
Allergic contact dermatitis prevalence in patients with otitis externa. 61
1675529 1991
15
Toxicology and Carcinogenesis Studies of 8-Methoxypsoralen (CAS No. 298-81-7) in F344/N Rats (Gavage Studies). 61
12695782 1989
16
Genetic counseling for skin diseases. A statistical analysis of 182 cases. 61
6642036 1983
17
Sister chromatid exchange in human populations: the effect of smoking, drug treatment, and occupational exposure. 61
7116939 1982
18
DNA repair in human cells containing photoadducts of 8-methoxypsoralen or angelicin. 61
7471088 1980
19
Monocytopoiesis in chronic eczematous diseases, psoriasis vulgaris, and mycosis fungoides. 61
1245754 1976

Variations for Psoriasis 8

Expression for Psoriasis 8

Search GEO for disease gene expression data for Psoriasis 8.

Pathways for Psoriasis 8

GO Terms for Psoriasis 8

Sources for Psoriasis 8

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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