Aliases & Classifications for Psychosexual Disorder

MalaCards integrated aliases for Psychosexual Disorder:

Name: Psychosexual Disorder 12 15
Psychosexual Disorders 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10132
ICD9CM 35 302.79
ICD10 33 F66.9

Summaries for Psychosexual Disorder

MalaCards based summary : Psychosexual Disorder, also known as psychosexual disorders, is related to rumination disorder and functional gastric disease, and has symptoms including genital pain An important gene associated with Psychosexual Disorder is PDE5A (Phosphodiesterase 5A), and among its related pathways/superpathways are Calcium signaling pathway and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Apremilast and Immunologic Factors have been mentioned in the context of this disorder. Affiliated tissues include prostate.

Wikipedia : 76 Psychosexual disorder is a sexual problem that is psychological, rather than physiological in origin.... more...

Related Diseases for Psychosexual Disorder

Diseases related to Psychosexual Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 71)
# Related Disease Score Top Affiliating Genes
1 rumination disorder 10.2 HTR7 HTR1A
2 functional gastric disease 10.2 PDE5A HTR7
3 motion sickness 10.2 HTR7 HTR1A
4 phobic disorder 10.2 SLC6A4 HTR1A
5 social phobia 10.1 SLC6A4 HTR1A
6 alexithymia 10.1 SLC6A4 HTR1A
7 agoraphobia 10.1 SLC6A4 HTR1A
8 amnestic disorder 10.1 HTR7 HTR1A
9 vasculogenic impotence 10.1 PDE5A ALDH7A1
10 schizoid personality disorder 10.1 HTR2A HTR1A
11 pulmonary hypertension, primary, 1 10.1 SLC6A4 PDE5A
12 substance-induced psychosis 10.1 HTR2A HTR1A
13 raynaud phenomenon 10.1 PDE5A HTR2A
14 migraine without aura 10.1 SLC6A4 HTR1A
15 coronary artery vasospasm 10.1 HTR7 HTR2A
16 dyspepsia 10.1 SLC6A4 HTR1A
17 transient global amnesia 10.1 PDE5A ALDH7A1
18 alcoholic psychosis 10.1 SLC6A4 HTR2A
19 irritable bowel syndrome 10.1 SLC6A4 HTR7
20 pathological gambling 10.1 SLC6A4 HTR2A
21 prostatic hyperplasia, benign 10.1 SHBG PDE5A
22 fibromyalgia 10.1 SLC6A4 HTR2A
23 paranoid schizophrenia 10.1 SLC6A4 HTR2A
24 kleptomania 10.0 SLC6A4 HTR7 HTR1A
25 eating disorder 10.0 HTR2C SLC6A4
26 intermittent explosive disorder 10.0 SLC6A4 HTR7 HTR1A
27 brunner syndrome 10.0 SLC6A4 HTR7 HTR1A
28 post-traumatic stress disorder 10.0 SLC6A4 HTR2A
29 drug psychosis 10.0 HTR7 HTR2A HTR1A
30 drug-induced mental disorder 10.0 HTR7 HTR2A HTR1A
31 bulimia nervosa 10.0 SLC6A4 HTR2A
32 atypical depressive disorder 10.0 SLC6A4 HTR7 HTR2A
33 serotonin syndrome 10.0 SLC6A4 HTR2A HTR1A
34 generalized anxiety disorder 10.0 SLC6A4 HTR2A HTR1A
35 dysthymic disorder 10.0 SLC6A4 HTR7 HTR2A
36 chronic fatigue syndrome 10.0 SLC6A4 HTR2A HTR1A
37 migraine with aura 10.0 SLC6A4 HTR2C
38 schizoaffective disorder 10.0 SLC6A4 HTR2A
39 sudden infant death syndrome 10.0 SLC6A4 HTR2A HTR1A
40 hypoactive sexual desire disorder 9.9 SHBG HTR2A HTR1A
41 alcohol abuse 9.9 SLC6A4 HTR2A
42 impotence 9.9 SHBG PDE5A ALDH7A1
43 premature ejaculation 9.9 SLC6A4 PDE5A HTR2C HTR1A
44 parkinson disease, late-onset 9.9 SLC6A4 HTR2A HTR1A
45 specific developmental disorder 9.9 SLC6A4 HTR7
46 alopecia, androgenetic, 1 9.9
47 alopecia 9.9
48 androgenic alopecia 9.9
49 infertility 9.9
50 vulvar vestibulitis syndrome 9.9

Graphical network of the top 20 diseases related to Psychosexual Disorder:



Diseases related to Psychosexual Disorder

Symptoms & Phenotypes for Psychosexual Disorder

UMLS symptoms related to Psychosexual Disorder:


genital pain

Drugs & Therapeutics for Psychosexual Disorder

Drugs for Psychosexual Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Apremilast Approved, Investigational Phase 2 608141-41-9 11561674
2 Immunologic Factors Phase 2
3 Anti-Bacterial Agents Phase 2
4 Anti-Infective Agents Phase 2
5 Peripheral Nervous System Agents Phase 2
6 Analgesics, Non-Narcotic Phase 2
7 Immunosuppressive Agents Phase 2
8 Analgesics Phase 2
9 Anti-Inflammatory Agents, Non-Steroidal Phase 2
10 Angiogenesis Modulating Agents Phase 2
11 Antirheumatic Agents Phase 2
12 Anti-Inflammatory Agents Phase 2
13 Angiogenesis Inhibitors Phase 2
14 Estrogens Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 CC-10004 For The Treatment Of Vulvodynia Completed NCT00814632 Phase 2 CC-10004
2 Urinary and Sexual Function Before and After Surgical Decompression of Cervical Myelopathy Unknown status NCT02059798
3 Developing a Stepped Approach to Improving Sexual Function aFteR Treatment fOr gyNaecological Cancer Unknown status NCT02458001 Not Applicable
4 Predictive Factors for Male Sexual Dysfunction After Traumatic Spinal Cord Injury Completed NCT02860689

Search NIH Clinical Center for Psychosexual Disorder

Genetic Tests for Psychosexual Disorder

Anatomical Context for Psychosexual Disorder

MalaCards organs/tissues related to Psychosexual Disorder:

41
Prostate

Publications for Psychosexual Disorder

Articles related to Psychosexual Disorder:

# Title Authors Year
1
The tendency towards the development of psychosexual disorders in androgenetic alopecia according to the different stages of hair loss: a cross-sectional study. ( 29723381 )
2018
2
Psychosexual disorders and dermatologists. ( 27294047 )
2016
3
Vulvar vestibulitis syndrome (VVS) is not primarily a psychosexual disorder. ( 10870796 )
2000
4
Infertility and psychosexual disorders: relationship in infertile couples. ( 11214514 )
2000
5
Psychosexual disorders in children and adolescents. ( 1737827 )
1992
6
Psychosexual disorders of young adulthood. ( 5493922 )
1970
7
Psychosexual disorders, acquired and preventable forms of behavior. ( 13983222 )
1962
8
Oestrogen and psychosexual disorders. ( 13844320 )
1959

Variations for Psychosexual Disorder

Expression for Psychosexual Disorder

Search GEO for disease gene expression data for Psychosexual Disorder.

Pathways for Psychosexual Disorder

GO Terms for Psychosexual Disorder

Cellular components related to Psychosexual Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.35 HTR1A HTR2A HTR2C HTR7 SLC6A4
2 integral component of presynaptic membrane GO:0099056 9.26 HTR2A SLC6A4
3 integral component of postsynaptic membrane GO:0099055 9.16 HTR2A SLC6A4
4 dendrite GO:0030425 8.92 HTR1A HTR2A HTR2C HTR7

Biological processes related to Psychosexual Disorder according to GeneCards Suite gene sharing:

(show all 15)
# Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.93 HTR1A HTR2A HTR2C HTR7 PDE5A
2 chemical synaptic transmission GO:0007268 9.73 HTR1A HTR2A HTR2C HTR7
3 response to drug GO:0042493 9.67 HTR2A HTR2C SLC6A4
4 positive regulation of MAP kinase activity GO:0043406 9.55 HTR2A PDE5A
5 phospholipase C-activating G protein-coupled receptor signaling pathway GO:0007200 9.52 HTR2A HTR2C
6 positive regulation of fat cell differentiation GO:0045600 9.51 HTR2A HTR2C
7 G protein-coupled serotonin receptor signaling pathway GO:0098664 9.5 HTR1A HTR2A HTR7
8 release of sequestered calcium ion into cytosol GO:0051209 9.48 HTR2A HTR2C
9 behavioral fear response GO:0001662 9.46 HTR1A HTR2C
10 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.46 HTR1A HTR2A HTR2C HTR7
11 vasoconstriction GO:0042310 9.43 HTR1A HTR7 SLC6A4
12 positive regulation of phosphatidylinositol biosynthetic process GO:0010513 9.4 HTR2A HTR2C
13 phospholipase C-activating serotonin receptor signaling pathway GO:0007208 9.37 HTR2A HTR2C
14 behavior GO:0007610 9.13 HTR1A HTR2A HTR2C
15 serotonin receptor signaling pathway GO:0007210 8.8 HTR1A HTR2A HTR2C

Molecular functions related to Psychosexual Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled receptor activity GO:0004930 9.62 HTR1A HTR2A HTR2C HTR7
2 neurotransmitter receptor activity GO:0030594 9.46 HTR1A HTR2A HTR2C HTR7
3 drug binding GO:0008144 9.37 HTR2A HTR2C
4 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding GO:0071886 9.26 HTR2A HTR2C
5 G protein-coupled serotonin receptor activity GO:0004993 9.26 HTR1A HTR2A HTR2C HTR7
6 serotonin binding GO:0051378 8.92 HTR1A HTR2A HTR2C SLC6A4

Sources for Psychosexual Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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