Aliases & Classifications for Psychosexual Disorder

MalaCards integrated aliases for Psychosexual Disorder:

Name: Psychosexual Disorder 12 15
Psychosexual Disorders 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10132
ICD9CM 35 302.79
ICD10 33 F66.9

Summaries for Psychosexual Disorder

MalaCards based summary : Psychosexual Disorder, also known as psychosexual disorders, is related to rumination disorder and functional gastric disease, and has symptoms including genital pain An important gene associated with Psychosexual Disorder is PDE5A (Phosphodiesterase 5A), and among its related pathways/superpathways are Calcium signaling pathway and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Apremilast and Analgesics have been mentioned in the context of this disorder. Affiliated tissues include spinal cord.

Wikipedia : 76 Psychosexual disorder is a term which may simply refer to a sexual problem that is psychological, rather... more...

Related Diseases for Psychosexual Disorder

Diseases related to Psychosexual Disorder via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 rumination disorder 10.6 HTR1A HTR7
2 functional gastric disease 10.5 HTR7 PDE5A
3 motion sickness 10.5 HTR1A HTR7
4 phobic disorder 10.5 HTR1A SLC6A4
5 social phobia 10.5 HTR1A SLC6A4
6 atypical depressive disorder 10.5 HTR7 SLC6A4
7 alexithymia 10.5 HTR1A SLC6A4
8 amnestic disorder 10.5 HTR1A HTR7
9 chronic pulmonary heart disease 10.5 HTR7 SLC6A4
10 agoraphobia 10.4 HTR1A SLC6A4
11 schizoid personality disorder 10.4 HTR1A HTR2A
12 substance-induced psychosis 10.4 HTR1A HTR2A
13 postpartum depression 10.4 HTR1A SLC6A4
14 migraine without aura 10.4 HTR1A SLC6A4
15 coronary artery vasospasm 10.3 HTR2A HTR7
16 dyspepsia 10.3 HTR1A SLC6A4
17 alzheimer disease 5 10.3 HTR2A SLC6A4
18 endogenous depression 10.3 HTR7 SLC6A4
19 alcoholic psychosis 10.3 HTR2A SLC6A4
20 pathological gambling 10.3 HTR2A SLC6A4
21 irritable bowel syndrome 10.2 HTR7 SLC6A4
22 bruxism 10.2 HTR2A SLC6A4
23 fibromyalgia 10.2 HTR2A SLC6A4
24 paranoid schizophrenia 10.2 HTR2A SLC6A4
25 early-onset schizophrenia 10.2 HTR2A SLC6A4
26 kleptomania 10.1 HTR1A HTR7 SLC6A4
27 intermittent explosive disorder 10.1 HTR1A HTR7 SLC6A4
28 brunner syndrome 10.1 HTR1A HTR7 SLC6A4
29 bulimia nervosa 10.1 HTR2A SLC6A4
30 eating disorder 10.1 HTR2C SLC6A4
31 impotence 10.1 PDE5A SHBG
32 drug-induced mental disorder 10.0 HTR1A HTR2A HTR7
33 drug psychosis 10.0 HTR1A HTR2A HTR7
34 migraine with aura 10.0 HTR2C SLC6A4
35 post-traumatic stress disorder 10.0 HTR2A SLC6A4
36 serotonin syndrome 9.9 HTR1A HTR2A SLC6A4
37 generalized anxiety disorder 9.9 HTR1A HTR2A SLC6A4
38 dysthymic disorder 9.9 HTR2A HTR7 SLC6A4
39 sexual disorder 9.9 HTR1A PDE5A SHBG
40 chronic fatigue syndrome 9.9 HTR1A SLC6A4
41 sudden infant death syndrome 9.9 HTR1A HTR2A SLC6A4
42 schizoaffective disorder 9.8 HTR2A SLC6A4
43 vulvar vestibulitis syndrome 9.8
44 hypoactive sexual desire disorder 9.7 HTR1A HTR2A SHBG
45 premature ejaculation 9.7 HTR1A HTR2C PDE5A SLC6A4
46 specific developmental disorder 9.7 HTR7 SLC6A4
47 parkinson disease, late-onset 9.6 HTR1A HTR2A SLC6A4
48 autism 9.5 HTR1A HTR2A HTR7 SLC6A4
49 periodic limb movement disorder 9.4 HTR1A HTR2A HTR2C SLC6A4
50 borderline personality disorder 9.4 HTR1A HTR2A HTR2C SLC6A4

Graphical network of the top 20 diseases related to Psychosexual Disorder:



Diseases related to Psychosexual Disorder

Symptoms & Phenotypes for Psychosexual Disorder

UMLS symptoms related to Psychosexual Disorder:


genital pain

Drugs & Therapeutics for Psychosexual Disorder

Drugs for Psychosexual Disorder (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 13)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Apremilast Approved, Investigational Phase 2 608141-41-9 11561674
2 Analgesics Phase 2
3 Analgesics, Non-Narcotic Phase 2
4 Angiogenesis Inhibitors Phase 2
5 Angiogenesis Modulating Agents Phase 2
6 Anti-Bacterial Agents Phase 2
7 Anti-Infective Agents Phase 2
8 Anti-Inflammatory Agents Phase 2
9 Anti-Inflammatory Agents, Non-Steroidal Phase 2
10 Antirheumatic Agents Phase 2
11 Immunosuppressive Agents Phase 2
12 Peripheral Nervous System Agents Phase 2
13 Estrogens Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 CC-10004 For The Treatment Of Vulvodynia Completed NCT00814632 Phase 2 CC-10004
2 Urinary and Sexual Function Before and After Surgical Decompression of Cervical Myelopathy Unknown status NCT02059798
3 Developing a Stepped Approach to Improving Sexual Function aFteR Treatment fOr gyNaecological Cancer Unknown status NCT02458001 Not Applicable
4 Predictive Factors for Male Sexual Dysfunction After Traumatic Spinal Cord Injury Completed NCT02860689

Search NIH Clinical Center for Psychosexual Disorder

Genetic Tests for Psychosexual Disorder

Anatomical Context for Psychosexual Disorder

MalaCards organs/tissues related to Psychosexual Disorder:

41
Spinal Cord

Publications for Psychosexual Disorder

Articles related to Psychosexual Disorder:

# Title Authors Year
1
Vulvar vestibulitis syndrome (VVS) is not primarily a psychosexual disorder. ( 10870796 )
2000

Variations for Psychosexual Disorder

Expression for Psychosexual Disorder

Search GEO for disease gene expression data for Psychosexual Disorder.

Pathways for Psychosexual Disorder

GO Terms for Psychosexual Disorder

Cellular components related to Psychosexual Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.35 HTR1A HTR2A HTR2C HTR7 SLC6A4
2 dendrite GO:0030425 8.92 HTR1A HTR2A HTR2C HTR7

Biological processes related to Psychosexual Disorder according to GeneCards Suite gene sharing:

(show all 18)
# Name GO ID Score Top Affiliating Genes
1 chemical synaptic transmission GO:0007268 9.73 HTR1A HTR2A HTR2C HTR7
2 response to drug GO:0042493 9.72 HTR2A HTR2C SLC6A4
3 phospholipase C-activating G-protein coupled receptor signaling pathway GO:0007200 9.58 HTR2A HTR2C
4 positive regulation of MAP kinase activity GO:0043406 9.57 HTR2A PDE5A
5 positive regulation of fat cell differentiation GO:0045600 9.56 HTR2A HTR2C
6 release of sequestered calcium ion into cytosol GO:0051209 9.54 HTR2A HTR2C
7 behavioral fear response GO:0001662 9.52 HTR1A HTR2C
8 G-protein coupled serotonin receptor signaling pathway GO:0098664 9.51 HTR1A HTR2A
9 smooth muscle contraction GO:0006939 9.49 HTR2A HTR7
10 regulation of behavior GO:0050795 9.48 HTR1A HTR2A
11 regulation of hormone secretion GO:0046883 9.46 HTR1A HTR2A
12 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger GO:0007187 9.46 HTR1A HTR2A HTR2C HTR7
13 vasoconstriction GO:0042310 9.43 HTR1A HTR7 SLC6A4
14 adenylate cyclase-inhibiting serotonin receptor signaling pathway GO:0007198 9.4 HTR1A HTR7
15 positive regulation of phosphatidylinositol biosynthetic process GO:0010513 9.37 HTR2A HTR2C
16 phospholipase C-activating serotonin receptor signaling pathway GO:0007208 9.32 HTR2A HTR2C
17 behavior GO:0007610 9.13 HTR1A HTR2A HTR2C
18 serotonin receptor signaling pathway GO:0007210 8.8 HTR1A HTR2A HTR2C

Molecular functions related to Psychosexual Disorder according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor activity GO:0004930 9.62 HTR1A HTR2A HTR2C HTR7
2 obsolete signal transducer activity GO:0004871 9.54 HTR1A HTR2A HTR2C
3 neurotransmitter receptor activity GO:0030594 9.46 HTR1A HTR2A HTR2C HTR7
4 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding GO:0071886 9.26 HTR2A HTR2C
5 G-protein coupled serotonin receptor activity GO:0004993 9.26 HTR1A HTR2A HTR2C HTR7
6 serotonin binding GO:0051378 8.92 HTR1A HTR2A HTR2C HTR7

Sources for Psychosexual Disorder

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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