MCID: PTH001
MIFTS: 30

Pthirus Pubis Infestation

Categories: Infectious diseases

Aliases & Classifications for Pthirus Pubis Infestation

MalaCards integrated aliases for Pthirus Pubis Infestation:

Name: Pthirus Pubis Infestation 12 15
Infestation by Phthirus Pubis 12 73
Phthirus/pediculus Pubis - Pubic Lice - Crabs 12
Pediculosis Pubis 12
Phthiriasis Pubis 12
Pediculus Pubis 12
Phthirus Pubis 12
Crabs 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13760
ICD10 33 B85.3
ICD9CM 35 132.2
NCIt 50 C35777
UMLS 73 C0030759

Summaries for Pthirus Pubis Infestation

Disease Ontology : 12 A lice infestation that involves parasitic infestation by pubic lice Pthirus pubis, which are found in the pubic hair, less commonly in eyebrows, eyelashes, beard, mustache, armpit, perianal area, groin, trunk and scalp. The symptoms include itching in the pubic and groin area. Intense itching leads to scratching which can cause sores and secondary bacterial infection of the skin.

MalaCards based summary : Pthirus Pubis Infestation, also known as infestation by phthirus pubis, is related to green mud crab allergy and late yaws. An important gene associated with Pthirus Pubis Infestation is MT-CO1 (Mitochondrially Encoded Cytochrome C Oxidase I). The drugs Daratumumab and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include skin and lung, and related phenotypes are Increased mitotic index and homeostasis/metabolism

Related Diseases for Pthirus Pubis Infestation

Diseases related to Pthirus Pubis Infestation via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 37)
# Related Disease Score Top Affiliating Genes
1 green mud crab allergy 11.9
2 late yaws 11.3
3 paragonimiasis 11.3
4 spondylocostal dysostosis 5 10.9
5 spondylospinal thoracic dysostosis 10.9
6 blepharoconjunctivitis 10.1
7 conjunctivitis 10.1
8 blepharitis 10.1
9 anoxia 10.0
10 hepatocellular carcinoma 9.7
11 prostate cancer 9.7
12 critical limb ischemia 9.7
13 keloids 9.7
14 keratoconus 9.7
15 limb ischemia 9.7
16 eosinophilic meningitis 9.7
17 disseminated intravascular coagulation 9.7
18 rabies 9.7
19 listeriosis 9.7
20 onchocerciasis 9.7
21 entropion 9.7
22 prostatitis 9.7
23 ischemia 9.7
24 plague 9.7
25 pneumonia 9.7
26 eosinophilic pneumonia 9.7
27 scabies 9.7
28 molluscum contagiosum 9.7
29 leishmaniasis 9.7
30 visceral leishmaniasis 9.7
31 meningitis 9.7
32 pellucid marginal degeneration 9.7
33 hymenolepiasis 9.7 MT-CO1 TMPRSS15
34 myiasis 9.6 ALPP MT-CO1
35 fascioliasis 9.2 ALPP MT-CO1
36 lice infestation 9.2 DTX1 MT-CO1 SLC27A4 TMEM132D
37 parasitic ectoparasitic infectious disease 9.2 ALPP MT-CO1 TMEM132D

Graphical network of the top 20 diseases related to Pthirus Pubis Infestation:



Diseases related to Pthirus Pubis Infestation

Symptoms & Phenotypes for Pthirus Pubis Infestation

GenomeRNAi Phenotypes related to Pthirus Pubis Infestation according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased mitotic index GR00110-A-0 8.62 MAPK13 TMPRSS15

MGI Mouse Phenotypes related to Pthirus Pubis Infestation:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.1 DTX1 HINT1 MAPK13 MT-CO1 SLC27A4 TMPRSS15

Drugs & Therapeutics for Pthirus Pubis Infestation

Drugs for Pthirus Pubis Infestation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 80)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Daratumumab Approved Phase 3 945721-28-8
2 Antibodies Phase 3,Phase 2
3 Antibodies, Monoclonal Phase 3,Phase 2
4 Immunoglobulins Phase 3,Phase 2
5
Bevacizumab Approved, Investigational Phase 2,Phase 1 216974-75-3
6
Capecitabine Approved, Investigational Phase 2 154361-50-9 60953
7
Iron Approved Phase 1, Phase 2 7439-89-6 23925
8
Omalizumab Approved, Investigational Phase 2 242138-07-4
9
Irinotecan Approved, Investigational Phase 1, Phase 2 97682-44-5, 100286-90-6 60838
10
Cyclophosphamide Approved, Investigational Phase 2 50-18-0, 6055-19-2 2907
11
Dexamethasone Approved, Investigational, Vet_approved Phase 2 50-02-2 5743
12
Lenalidomide Approved Phase 2 191732-72-6 216326
13 Siltuximab Approved, Investigational Phase 2 541502-14-1
14
Camptothecin Experimental Phase 1, Phase 2 7689-03-4
15 Angiogenesis Inhibitors Phase 2,Phase 1
16 Angiogenesis Modulating Agents Phase 2,Phase 1
17 Antimetabolites Phase 2,Not Applicable
18 Antimetabolites, Antineoplastic Phase 2
19 Micronutrients Phase 1, Phase 2
20 Trace Elements Phase 1, Phase 2
21 Anti-Bacterial Agents Phase 2,Phase 1,Not Applicable
22 Anti-Infective Agents Phase 2,Phase 1,Not Applicable
23 Anti-Allergic Agents Phase 2
24 Anti-Asthmatic Agents Phase 2
25 Respiratory System Agents Phase 2
26 Immunosuppressive Agents Phase 2,Phase 1
27 Antineoplastic Agents, Phytogenic Phase 1, Phase 2
28 topoisomerase I inhibitors Phase 1, Phase 2
29 Topoisomerase Inhibitors Phase 1, Phase 2
30 Alkylating Agents Phase 2
31 Antiemetics Phase 2
32 Anti-Inflammatory Agents Phase 2,Not Applicable
33 Antineoplastic Agents, Alkylating Phase 2
34 Antineoplastic Agents, Hormonal Phase 2
35 Antirheumatic Agents Phase 2
36 Autonomic Agents Phase 2
37 BB 1101 Phase 2
38 Dexamethasone acetate Phase 2 1177-87-3
39 Gastrointestinal Agents Phase 2
40 glucocorticoids Phase 2
41 HIV Protease Inhibitors Phase 2
42 Hormone Antagonists Phase 2
43 Hormones Phase 2
44 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
45 Peripheral Nervous System Agents Phase 2
46
protease inhibitors Phase 2
47
Carboplatin Approved Phase 1 41575-94-4 10339178 498142 38904
48
Everolimus Approved Phase 1 159351-69-6 6442177
49
Miconazole Approved, Investigational, Vet_approved Phase 1 22916-47-8 4189
50
Pemetrexed Approved, Investigational Phase 1 150399-23-8, 137281-23-3 446556 60843

Interventional clinical trials:

(show all 25)
# Name Status NCT ID Phase Drugs
1 Pom-dex Versus Pom-Cyclo-dex in MM Patients With Biochemical or Clinical Relapse, During Lena Maintenance Treatment Recruiting NCT03440411 Phase 3 Pomalidomide;Cyclophosphamide;Dexamethasone
2 A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma Recruiting NCT03301220 Phase 3 Daratumumab SC: daratumumab + rHuPH20
3 Preoperative Radiotherapy With Capecitabine and Bevacizumab in Locally Advanced Rectal Cancer: CRAB Phase II Study Unknown status NCT00842686 Phase 2 bevacizumab, capecitabine
4 Effect of Ejiao Compound in the Treatment of Postpartum Anemia of Qi-blood Deficiency Syndrome Unknown status NCT02656225 Phase 1, Phase 2 Ejiao compound;Niferex
5 A Study of Xolair in Peanut-Allergic Subjects Previously Enrolled in Study Q2788g Completed NCT00382148 Phase 2 omalizumab
6 Study of Carfilzomib With Irinotecan in Irinotecan-Sensitive Malignancies and Small Cell Lung Cancer Patients Recruiting NCT01941316 Phase 1, Phase 2 Carfilzomib;Irinotecan
7 Cyclophosphamide With Biochemical Progression During Lenalidomide-Dexamethasone Treatment for Relapsed/Refractory Multiple Myeloma (MM) Active, not recruiting NCT02206503 Phase 2 Cyclophosphamide;Lenalidomide;Dexamethasone
8 A Study of Siltuximab (Anti- IL 6 Monoclonal Antibody) in Patients With High-risk Smoldering Multiple Myeloma Active, not recruiting NCT01484275 Phase 2 Siltuximab;Placebo
9 A Phase II Trial of Anti-KIR in Smoldering Multiple Myeloma Terminated NCT01248455 Phase 2 (Anti-KIR)
10 Study of Everolimus, Pemetrexed, Carboplatin, and Bevacizumab to Treat Stage IV Lung Cancer Completed NCT01700400 Phase 1 Everolimus;Pemetrexed;Carboplatin;Bevacizumab
11 Randomized Double-Blind Placebo-Controlled Crab or Shrimp Allergy Reduction Study Using Nambudripad Allergy Elimination Techniques Unknown status NCT02208414 Not Applicable
12 Preauthorization Versus Prospective Audit in Antimicrobial Stewardship Program Unknown status NCT02837081 Not Applicable
13 Crabmeat and Health Study Completed NCT03104530
14 Impact of Plasma Levels of Colistin in Patients With Carbapenem Resistant Acinetobacter Baumannii Infection Completed NCT02482961 colistimethate sodium
15 "Association Splitting" in Obsessive-Compulsive Disorder (OCD) Completed NCT01035242 Not Applicable
16 Correlation Between Estimated Right Atrial Pressure and BNP in Pulmonary HTN (CRAB-PH) Recruiting NCT02873039
17 Pilot Study on Traditional Chinese Medicine and Food Allergy Recruiting NCT02490813 Not Applicable
18 European Prospective Cohort Study on Enterobacteriaceae Showing Resistance to Carbapenems Recruiting NCT02709408
19 High Dose Therapy Followed by Autologous Transplantation for Myeloma Patients With Severe Renal Impairment Recruiting NCT03234335
20 Project Survival-Prospective Biomarker Discovery Recruiting NCT02781012
21 Clinical and Sociodemographic Characterization of Multiple Myeloma Patients With Symptomatic Relapse and/or Refractory Disease in Spain (CharisMMa Study) Recruiting NCT03188536
22 Effectiveness of Chlorhexidine Bathing in the Neonatal Intensive Care Unit Recruiting NCT02537964 Not Applicable
23 Real-world Use of Carfilzomib Among Multiple Myeloma Patients in Europe Recruiting NCT03091127
24 Multiple Myeloma (MM) Profile in Brazil: A Retrospective Observational Analysis Not yet recruiting NCT03506386
25 Treatment of Mild to Moderate Peri-implantitis Using an Oscillating Chitosan Device Not yet recruiting NCT03373448 Not Applicable

Search NIH Clinical Center for Pthirus Pubis Infestation

Genetic Tests for Pthirus Pubis Infestation

Anatomical Context for Pthirus Pubis Infestation

MalaCards organs/tissues related to Pthirus Pubis Infestation:

41
Skin, Lung

Publications for Pthirus Pubis Infestation

Articles related to Pthirus Pubis Infestation:

# Title Authors Year
1
The treatment of Pthirus pubis infestation of the eyelashes. ( 3322357 )
1987

Variations for Pthirus Pubis Infestation

Expression for Pthirus Pubis Infestation

Search GEO for disease gene expression data for Pthirus Pubis Infestation.

Pathways for Pthirus Pubis Infestation

GO Terms for Pthirus Pubis Infestation

Molecular functions related to Pthirus Pubis Infestation according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleotide binding GO:0000166 9.13 HINT1 MAPK13 SLC27A4
2 catalytic activity GO:0003824 8.8 ALPP HINT1 SLC27A4

Sources for Pthirus Pubis Infestation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....