MCID: PRP011
MIFTS: 22

Puerperal Pulmonary Embolism

Categories: Cardiovascular diseases, Reproductive diseases, Respiratory diseases

Aliases & Classifications for Puerperal Pulmonary Embolism

MalaCards integrated aliases for Puerperal Pulmonary Embolism:

Name: Puerperal Pulmonary Embolism 12 15
Obstetric Pulmonary Embolism 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8512
ICD9CM 34 673
SNOMED-CT 67 237341004
ICD10 32 O88.21
UMLS 71 C0157540

Summaries for Puerperal Pulmonary Embolism

MalaCards based summary : Puerperal Pulmonary Embolism, also known as obstetric pulmonary embolism, is related to pulmonary embolism and acquired hemophilia, and has symptoms including puerperal pyrexia of unknown origin An important gene associated with Puerperal Pulmonary Embolism is ST3GAL1 (ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Formation of Fibrin Clot (Clotting Cascade).

Related Diseases for Puerperal Pulmonary Embolism

Diseases related to Puerperal Pulmonary Embolism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 76)
# Related Disease Score Top Affiliating Genes
1 pulmonary embolism 29.8 SERPINC1 F10 APOH
2 acquired hemophilia 10.2 F11 F10
3 hemarthrosis 10.2 F11 F10
4 factor x deficiency 10.1 F11 F10
5 carotid artery occlusion 10.1 F11 APOH
6 heparin-induced thrombocytopenia 10.1 SERPINC1 F10
7 purpura 10.1 SERPINC1 APOH
8 leech infestation 10.1 SERPINC1 F10
9 spinal cord infarction 10.1 SERPINC1 APOH
10 hepatic infarction 10.1 SERPINC1 APOH
11 livedoid vasculitis 10.1 SERPINC1 APOH
12 branch retinal artery occlusion 10.1 SERPINC1 APOH
13 splenic infarction 10.1 SERPINC1 APOH
14 syphilitic meningitis 10.1 SERPINC1 APOH
15 nonbacterial thrombotic endocarditis 10.0 SERPINC1 APOH
16 endocarditis 10.0 SERPINC1 APOH
17 sneddon syndrome 10.0 SERPINC1 APOH
18 papilledema 10.0 SERPINC1 APOH
19 peripheral vertigo 10.0 SERPINC1 APOH
20 factor vii deficiency 10.0 SERPINC1 F10
21 thrombophlebitis 10.0 SERPINC1 APOH
22 ischemic colitis 10.0 SERPINC1 APOH
23 central retinal vein occlusion 10.0 SERPINC1 APOH
24 thalassemia 10.0
25 retinal vein occlusion 10.0 SERPINC1 APOH
26 legg-calve-perthes disease 10.0 SERPINC1 APOH
27 portal vein thrombosis 10.0 SERPINC1 APOH
28 eclampsia 10.0 SERPINC1 PGF
29 autoimmune disease of cardiovascular system 10.0 SERPINC1 APOH
30 protein c deficiency 10.0 SERPINC1 APOH
31 intracranial hypertension 9.9 SERPINC1 APOH
32 nonarteritic anterior ischemic optic neuropathy 9.9 SERPINC1 APOH
33 prothrombin deficiency 9.9 SERPINC1 F11 F10
34 carotid artery thrombosis 9.9 SERPINC1 F11 F10
35 thrombotic thrombocytopenic purpura 9.9 SERPINC1 APOH
36 factor xi deficiency 9.9 SERPINC1 F11 F10
37 factor viii deficiency 9.9 SERPINC1 F11 F10
38 afibrinogenemia, congenital 9.9 SERPINC1 F11 F10
39 budd-chiari syndrome 9.9 SERPINC1 APOH
40 factor xii deficiency 9.9 SERPINC1 F11 APOH
41 prothrombin deficiency, congenital 9.9 SERPINC1 F10 APOH
42 intermittent claudication 9.9 SERPINC1 PGF
43 antithrombin iii deficiency 9.9 SERPINC1 F10 APOH
44 thrombophilia due to activated protein c resistance 9.9 SERPINC1 F10 APOH
45 protein s deficiency 9.9 SERPINC1 F10 APOH
46 vein disease 9.9 SERPINC1 PGF
47 lateral myocardial infarction 9.9 SERPINC1 SERPINA1
48 thrombophilia due to thrombin defect 9.9 SERPINC1 F10 APOH
49 esophageal varix 9.8 SERPINC1 SERPINA1
50 antiphospholipid syndrome 9.8 SERPINC1 F10 APOH

Graphical network of the top 20 diseases related to Puerperal Pulmonary Embolism:



Diseases related to Puerperal Pulmonary Embolism

Symptoms & Phenotypes for Puerperal Pulmonary Embolism

UMLS symptoms related to Puerperal Pulmonary Embolism:


puerperal pyrexia of unknown origin

Drugs & Therapeutics for Puerperal Pulmonary Embolism

Search Clinical Trials , NIH Clinical Center for Puerperal Pulmonary Embolism

Genetic Tests for Puerperal Pulmonary Embolism

Anatomical Context for Puerperal Pulmonary Embolism

Publications for Puerperal Pulmonary Embolism

Articles related to Puerperal Pulmonary Embolism:

# Title Authors PMID Year
1
Sudden maternal deaths probably due to obstetrical pulmonary embolism in Malaysia for 1991. 61
8057992 1994
2
Sickle-cell trait, thalassemia, G-6-PD deficiency and puerperal pulmonary embolism. 61
972663 1976

Variations for Puerperal Pulmonary Embolism

Expression for Puerperal Pulmonary Embolism

Search GEO for disease gene expression data for Puerperal Pulmonary Embolism.

Pathways for Puerperal Pulmonary Embolism

GO Terms for Puerperal Pulmonary Embolism

Cellular components related to Puerperal Pulmonary Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.63 ST3GAL1 SERPINC1 SERPINA1 F11 CD22 APOH
2 collagen-containing extracellular matrix GO:0062023 9.5 SERPINC1 SERPINA1 APOH
3 endoplasmic reticulum lumen GO:0005788 9.43 SERPINC1 SERPINA1 F10
4 extracellular space GO:0005615 9.43 SERPINC1 SERPINA1 PGF F11 F10 APOH
5 extracellular region GO:0005576 9.23 ST6GAL1 ST3GAL1 SERPINC1 SERPINA1 PGF F11

Biological processes related to Puerperal Pulmonary Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.46 SERPINC1 SERPINA1 F11 F10
2 O-glycan processing GO:0016266 9.43 ST6GAL1 ST3GAL1
3 sialylation GO:0097503 9.4 ST6GAL1 ST3GAL1
4 blood coagulation, intrinsic pathway GO:0007597 9.37 F11 APOH
5 plasminogen activation GO:0031639 9.32 F11 APOH
6 N-acetylneuraminate metabolic process GO:0006054 9.26 ST6GAL1 ST3GAL1
7 regulation of blood coagulation GO:0030193 9.13 SERPINC1 F11 APOH
8 hemostasis GO:0007599 8.92 SERPINC1 SERPINA1 F11 F10

Molecular functions related to Puerperal Pulmonary Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sialyltransferase activity GO:0008373 8.96 ST6GAL1 ST3GAL1
2 heparin binding GO:0008201 8.92 SERPINC1 PGF F11 APOH

Sources for Puerperal Pulmonary Embolism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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