MCID: PRP011
MIFTS: 23

Puerperal Pulmonary Embolism

Categories: Cardiovascular diseases, Reproductive diseases, Respiratory diseases

Aliases & Classifications for Puerperal Pulmonary Embolism

MalaCards integrated aliases for Puerperal Pulmonary Embolism:

Name: Puerperal Pulmonary Embolism 12 15
Obstetric Pulmonary Embolism 71

Classifications:



External Ids:

Disease Ontology 12 DOID:8512
ICD9CM 34 673
SNOMED-CT 67 50286006
ICD10 32 O88.21 O88.23
UMLS 71 C0157540

Summaries for Puerperal Pulmonary Embolism

MalaCards based summary : Puerperal Pulmonary Embolism, also known as obstetric pulmonary embolism, is related to pulmonary embolism and acquired hemophilia, and has symptoms including puerperal pyrexia of unknown origin An important gene associated with Puerperal Pulmonary Embolism is ST3GAL1 (ST3 Beta-Galactoside Alpha-2,3-Sialyltransferase 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Formation of Fibrin Clot (Clotting Cascade). Related phenotype is immune system.

Related Diseases for Puerperal Pulmonary Embolism

Diseases related to Puerperal Pulmonary Embolism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 68)
# Related Disease Score Top Affiliating Genes
1 pulmonary embolism 29.3 SERPINC1 F10 APOH
2 acquired hemophilia 10.2 F11 F10
3 carotid artery occlusion 10.2 F11 APOH
4 hemarthrosis 10.2 F11 F10
5 factor x deficiency 10.2 F11 F10
6 factor viii deficiency 10.2 F11 F10
7 thalassemia 10.0
8 carney complex variant 9.9 IGF1 F10
9 spinal cord infarction 9.9 SERPINC1 APOH
10 sudden sensorineural hearing loss 9.9 SERPINC1 APOH
11 hepatic infarction 9.9 SERPINC1 APOH
12 splenic infarction 9.9 SERPINC1 APOH
13 heparin-induced thrombocytopenia 9.8 SERPINC1 F10
14 papilledema 9.8 SERPINC1 APOH
15 sneddon syndrome 9.8 SERPINC1 APOH
16 persistent fetal circulation syndrome 9.8 PGF IGF1
17 peripheral vertigo 9.8 SERPINC1 APOH
18 leech infestation 9.8 SERPINC1 F10
19 carotid artery thrombosis 9.8 SERPINC1 F10
20 ischemic colitis 9.8 SERPINC1 APOH
21 purpura fulminans 9.8 SERPINC1 APOH
22 purpura 9.8 SERPINC1 APOH
23 thrombophlebitis 9.8 SERPINC1 APOH
24 legg-calve-perthes disease 9.8 SERPINC1 APOH
25 central retinal vein occlusion 9.8 SERPINC1 APOH
26 retinal vein occlusion 9.8 SERPINC1 APOH
27 intracranial arteriosclerosis 9.8 SERPINC1 IGF1
28 portal vein thrombosis 9.7 SERPINC1 APOH
29 protein c deficiency 9.7 SERPINC1 APOH
30 factor vii deficiency 9.7 SERPINC1 F10
31 intracranial hypertension 9.7 SERPINC1 APOH
32 mild pre-eclampsia 9.7 SERPINC1 PGF
33 factor xii deficiency 9.6 SERPINC1 F11 APOH
34 prothrombin deficiency 9.6 SERPINC1 F11 F10
35 factor xi deficiency 9.6 SERPINC1 F11 F10
36 inherited blood coagulation disease 9.6 SERPINC1 F11 F10
37 thrombotic thrombocytopenic purpura 9.6 SERPINC1 APOH
38 hemophilia b 9.6 SERPINC1 F11 F10
39 hemorrhagic disease 9.6 SERPINC1 F11 F10
40 afibrinogenemia, congenital 9.6 SERPINC1 F11 F10
41 disseminated intravascular coagulation 9.6 SERPINC1 F11 F10
42 prothrombin deficiency, congenital 9.6 SERPINC1 F10 APOH
43 intracranial thrombosis 9.6 SERPINC1 F10 APOH
44 thrombophilia due to activated protein c resistance 9.6 SERPINC1 F10 APOH
45 antithrombin iii deficiency 9.6 SERPINC1 F10 APOH
46 budd-chiari syndrome 9.6 SERPINC1 APOH
47 tuberous sclerosis 2 9.6 SERPINC1 IGF1
48 protein s deficiency 9.6 SERPINC1 F10 APOH
49 thrombophilia due to thrombin defect 9.6 SERPINC1 F10 APOH
50 blood platelet disease 9.5 SERPINC1 F10 APOH

Graphical network of the top 20 diseases related to Puerperal Pulmonary Embolism:



Diseases related to Puerperal Pulmonary Embolism

Symptoms & Phenotypes for Puerperal Pulmonary Embolism

UMLS symptoms related to Puerperal Pulmonary Embolism:


puerperal pyrexia of unknown origin

MGI Mouse Phenotypes related to Puerperal Pulmonary Embolism:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 immune system MP:0005387 9.17 CD22 F11 IGF1 PGF SERPINC1 ST3GAL1

Drugs & Therapeutics for Puerperal Pulmonary Embolism

Search Clinical Trials , NIH Clinical Center for Puerperal Pulmonary Embolism

Genetic Tests for Puerperal Pulmonary Embolism

Anatomical Context for Puerperal Pulmonary Embolism

Publications for Puerperal Pulmonary Embolism

Articles related to Puerperal Pulmonary Embolism:

# Title Authors PMID Year
1
Sudden maternal deaths probably due to obstetrical pulmonary embolism in Malaysia for 1991. 61
8057992 1994
2
Sickle-cell trait, thalassemia, G-6-PD deficiency and puerperal pulmonary embolism. 61
972663 1976

Variations for Puerperal Pulmonary Embolism

Expression for Puerperal Pulmonary Embolism

Search GEO for disease gene expression data for Puerperal Pulmonary Embolism.

Pathways for Puerperal Pulmonary Embolism

GO Terms for Puerperal Pulmonary Embolism

Cellular components related to Puerperal Pulmonary Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.43 SERPINC1 PGF IGF1 F11 F10 APOH
2 extracellular region GO:0005576 9.23 ST6GAL1 ST3GAL1 SERPINC1 PGF IGF1 F11

Biological processes related to Puerperal Pulmonary Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.61 SERPINC1 F11 F10
2 O-glycan processing GO:0016266 9.46 ST6GAL1 ST3GAL1
3 sialylation GO:0097503 9.4 ST6GAL1 ST3GAL1
4 blood coagulation, intrinsic pathway GO:0007597 9.37 F11 APOH
5 plasminogen activation GO:0031639 9.32 F11 APOH
6 negative regulation of smooth muscle cell apoptotic process GO:0034392 9.26 IGF1 APOH
7 N-acetylneuraminate metabolic process GO:0006054 9.16 ST6GAL1 ST3GAL1
8 hemostasis GO:0007599 9.13 SERPINC1 F11 F10
9 regulation of blood coagulation GO:0030193 8.8 SERPINC1 F11 APOH

Molecular functions related to Puerperal Pulmonary Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sialyltransferase activity GO:0008373 8.96 ST6GAL1 ST3GAL1
2 heparin binding GO:0008201 8.92 SERPINC1 PGF F11 APOH

Sources for Puerperal Pulmonary Embolism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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