MCID: PLM007
MIFTS: 30

Pulmonary Aspergilloma

Categories: Blood diseases, Immune diseases, Infectious diseases, Respiratory diseases

Aliases & Classifications for Pulmonary Aspergilloma

MalaCards integrated aliases for Pulmonary Aspergilloma:

Name: Pulmonary Aspergilloma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050153

Summaries for Pulmonary Aspergilloma

Disease Ontology : 12 An aspergillosis that presents as a clump of tangled mass of Aspergillus fungus fibres, blood clots, and white blood cells, which exists in the cavities of the lungs that develop in an area of previous lung disease or lung scarring.

MalaCards based summary : Pulmonary Aspergilloma is related to aspergillosis and suppurative lymphadenitis. An important gene associated with Pulmonary Aspergilloma is VEGFA (Vascular Endothelial Growth Factor A), and among its related pathways/superpathways is Development_Leptin signaling via JAK/STAT and MAPK cascades. The drugs Miconazole and Itraconazole have been mentioned in the context of this disorder. Affiliated tissues include lung, thyroid and heart.

Related Diseases for Pulmonary Aspergilloma

Diseases related to Pulmonary Aspergilloma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)
# Related Disease Score Top Affiliating Genes
1 aspergillosis 10.3
2 suppurative lymphadenitis 10.2 DOCK8 P3H2
3 spinal disease 10.2 CRP VEGFA
4 cardiac rupture 10.2 CRP FLNC
5 bronchopneumonia 10.2 MPO P3H2
6 leukostasis 10.2 MPO VEGFA
7 lipid pneumonia 10.2 CRP FLNC
8 pyuria 10.2 CRP NUMA1
9 pleural empyema 10.2 CRP P3H2
10 pyelitis 10.2 CRP P3H2
11 gastrointestinal tuberculosis 10.2 CRP SMUG1
12 hydrops, lactic acidosis, and sideroblastic anemia 10.2 MPO VEGFA
13 subdural empyema 10.2 CRP P3H2
14 lung cancer 10.2
15 actinomycosis 10.2
16 cartilage disease 10.2 CRP SMUG1
17 mononeuritis multiplex 10.2 CRP MPO
18 benign struma ovarii 10.2 SMUG1 TG
19 colloid adenoma 10.2 SMUG1 TG
20 mediastinitis 10.2 CRP MPO
21 central nervous system vasculitis 10.2 CRP SMUG1
22 mature teratoma 10.1 SMUG1 TG
23 tuberculous peritonitis 10.1 CRP SMUG1
24 rapidly progressive glomerulonephritis 10.1 CRP MPO
25 pericardium disease 10.1 CRP SMUG1
26 lemierre's syndrome 10.1 CRP SMUG1
27 pericardium cancer 10.1 MPO SMUG1
28 suppurative thyroiditis 10.1 CRP TG
29 hypersensitivity vasculitis 10.1 CRP MPO
30 endocardium disease 10.1 CRP SMUG1
31 intermittent explosive disorder 10.1 CRP SMUG1
32 peliosis hepatis 10.1 HADHA SMUG1 VEGFA
33 hypersensitivity reaction type iii disease 10.1 CRP MPO
34 castleman disease 10.1 CRP VEGFA
35 subacute thyroiditis 10.1 CRP TG
36 pulmonary hemosiderosis 10.1 CRP MPO
37 lymphangiosarcoma 10.1 SMUG1 VEGFA
38 henoch-schoenlein purpura 10.1 CRP MPO
39 gastrointestinal system disease 10.1 CRP SMUG1 VEGFA
40 arteritic anterior ischemic optic neuropathy 10.1 CRP MPO
41 nervous system disease 10.1 CRP SMUG1 VEGFA
42 pericardial mesothelioma 10.1 MPO SMUG1
43 proctitis 10.1 CRP MPO
44 endocrine gland cancer 10.1 SMUG1 TG VEGFA
45 xanthogranulomatous pyelonephritis 10.1 CRP NUMA1 SMUG1
46 immune system disease 10.0 CRP FLNC TG
47 polyarteritis nodosa 10.0 CRP MPO
48 aortitis 10.0 CRP MPO SMUG1
49 muscular disease 10.0 CRP FLNC SMUG1
50 myeloma, multiple 10.0 CRP SMUG1 VEGFA

Graphical network of the top 20 diseases related to Pulmonary Aspergilloma:



Diseases related to Pulmonary Aspergilloma

Symptoms & Phenotypes for Pulmonary Aspergilloma

Drugs & Therapeutics for Pulmonary Aspergilloma

Drugs for Pulmonary Aspergilloma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 12)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2 22916-47-8 4189
2
Itraconazole Approved, Investigational Phase 3,Phase 2 84625-61-6 55283
3 Cytochrome P-450 CYP3A Inhibitors Phase 3,Phase 2
4 Hormone Antagonists Phase 3,Phase 2
5 Cytochrome P-450 Enzyme Inhibitors Phase 3,Phase 2
6 Pharmaceutical Solutions Phase 3,Phase 2
7 Antifungal Agents Phase 3,Phase 2
8 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3,Phase 2
9
Hydroxyitraconazole Phase 3,Phase 2
10 Anti-Infective Agents Phase 3,Phase 2
11 Steroid Synthesis Inhibitors Phase 3,Phase 2
12 Hormones Phase 3,Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Pharmacokinetic Study of JK1211(Itraconazole [Itrizole]) Oral Solution in Participants With Deep Mycosis and Those With Febrile Neutropenia Suspected of Fungal Infection Completed NCT00784368 Phase 3 ITCZ Oral Solution;ITCZ-IV
2 Efficacy of Intrabronchial Voriconazole Instillation for Inoperable Pulmonary Aspergilloma Recruiting NCT03799809 Phase 2, Phase 3 Intrabronchial Voriconazole instillation
3 A Multicenter, Prospective, Randomized, Double-Blind Clinical Trial Comparing Itraconazole Oral Solution in Cyclodextrin to Placebo in the Treatment of Aspergilloma Completed NCT00005668 Phase 2 Itraconazole oral solution
4 Outcome After Treatment of Pulmonary Aspergilloma Unknown status NCT01958710

Search NIH Clinical Center for Pulmonary Aspergilloma

Genetic Tests for Pulmonary Aspergilloma

Anatomical Context for Pulmonary Aspergilloma

MalaCards organs/tissues related to Pulmonary Aspergilloma:

41
Lung, Thyroid, Heart, Endothelial, B Cells, Cervix

Publications for Pulmonary Aspergilloma

Articles related to Pulmonary Aspergilloma:

(show top 50) (show all 188)
# Title Authors Year
1
Pulmonary Aspergilloma with Oxalosis. ( 29709953 )
2018
2
Feasibility of surgery for pulmonary aspergilloma: analysis of the operative modes. ( 29542058 )
2018
3
Pulmonary aspergilloma mimicking synchronous lung cancer on PET/CT in a patient with head and neck cancer. ( 29361322 )
2018
4
Complex Pulmonary Aspergilloma: Surgical Challenges in a Third World Setting. ( 29594190 )
2018
5
Pulmonary Actinomycosis Mimicking Pulmonary Aspergilloma and a Brief Review of the Literature. ( 28202870 )
2017
6
Intervention treatment on massive hemoptysis of pulmonary aspergilloma. ( 28565835 )
2017
7
Video-assisted thoracoscopic surgery for pulmonary aspergilloma. ( 28671161 )
2017
8
Sublobar Resection for Pulmonary Aspergilloma: A Safe Alternative toA Lobectomy. ( 28366461 )
2017
9
Coexistence of Pulmonary Aspergilloma and Allergic Bronchopulmonary Aspergillosis. ( 28768986 )
2017
10
Surgical treatment for pulmonary aspergilloma - early and long-term results. ( 28747940 )
2017
11
Pulmonary Hypertension and Pulmonary Aspergilloma-Coexistence of Two Rare Sequelae of Pulmonary Embolism. ( 27408402 )
2016
12
Cystic Bronchiectasis Imitating Pulmonary Aspergilloma. ( 27569246 )
2016
13
Pulmonary aspergilloma: An evasive disease. ( 27242239 )
2016
14
A Series of Transbronchial Removal of Intracavitary Pulmonary Aspergilloma. ( 27765172 )
2016
15
Intrabronchial Voriconazole is a Safe and Effective Measure for Hemoptysis Control in Pulmonary Aspergilloma. ( 27623423 )
2016
16
Genome sequence comparison of Aspergillus fumigatus strains isolated from patients with pulmonary aspergilloma and chronic necrotizing pulmonary aspergillosis. ( 25851262 )
2015
17
Lung resection in pulmonary aspergilloma: experience of a Moroccan center. ( 26475478 )
2015
18
A comparative study of itraconazole in various dose schedules in the treatment of pulmonary aspergilloma in treated patients of pulmonary tuberculosis. ( 26180383 )
2015
19
Intracavitary pulmonary aspergilloma: endoscopic aspects. ( 26176528 )
2015
20
Interstitial Lung Disease in Systemic Scleroderma, Complicated with Bilateral Pulmonary Aspergilloma: An Unusual Association. ( 26816937 )
2015
21
Surgical management of pulmonary aspergilloma: clinical experience with 77 cases. ( 26084137 )
2015
22
Results of surgical treatment for pulmonary aspergilloma. ( 25786611 )
2015
23
A rare case of calcified pulmonary aspergilloma. ( 24669092 )
2014
24
Video-assisted thoracic surgery for pulmonary aspergilloma: a safe and effective procedure. ( 24094518 )
2014
25
Complex pulmonary aspergilloma treated by cavernostomy. ( 25742406 )
2014
26
Direct transbronchial administration of liposomal amphotericin B into a pulmonary aspergilloma. ( 26029520 )
2014
27
Pulmonary aspergilloma: an unexpected complication of radiofrequency ablation in the management of targeted therapy for a patient with metastatic renal cell carcinoma. ( 24524970 )
2014
28
Simplified cavernostomy using wound protector for complex pulmonary aspergilloma. ( 24996732 )
2014
29
Pulmonary aspergilloma: A rare differential diagnosis to lung cancer after positive FDG PET scan. ( 26029524 )
2014
30
Is video-assisted thoracic surgery a versatile treatment for both simple and complex pulmonary aspergilloma? ( 24605221 )
2014
31
Clinical course and prognostic factors of pulmonary aspergilloma. ( 24995570 )
2014
32
A case of pulmonary aspergilloma without actinomycosis. ( 23618798 )
2013
33
Always expect the unexpected: lung abscess due to pseudomonas aeruginosa mimicking pulmonary aspergilloma in acute B-cell leukemia. ( 24166086 )
2013
34
Pulmonary aspergilloma: a treatment challenge in sub-Saharan Africa. ( 24205413 )
2013
35
A modern series of percutaneous intracavitary instillation of amphotericin B for the treatment of severe hemoptysis from pulmonary aspergilloma. ( 23117277 )
2013
36
First case report of single port video-assisted thoracoscopic middle lobectomy for the treatment of pulmonary aspergilloma in a pediatric patient. ( 25755940 )
2013
37
Endovascular aortic repair for a pulmonary aspergilloma fistulized into the descending aorta: selective intubation with a single-lumen tube under fluoroscopic guidance. ( 23242989 )
2013
38
Treatment of pulmonary aspergilloma in Srinagarind Hospital. ( 24386754 )
2013
39
A Case of Pulmonary Aspergilloma Treated with Radiofrequency Ablation. ( 24196265 )
2013
40
Bronchoscopic removal of a large intracavitary pulmonary aspergilloma. ( 23276848 )
2013
41
Pulmonary Aspergilloma in a Cavity Formed After Percutaneous Radiofrequency Ablation. ( 23636252 )
2013
42
A case of pulmonary aspergilloma without actinomycosis. ( 23538562 )
2013
43
Surgical treatment for pulmonary aspergilloma: a 35-year experience in the Chinese population. ( 22499801 )
2012
44
Pulmonary aspergilloma in patient with anorexia nervosa: case report. ( 22374072 )
2012
45
The clinical efficacy and safety of micafungin-itraconazole combination therapy in patients with pulmonary aspergilloma. ( 22350405 )
2012
46
Pulmonary aspergilloma treated by limited thoracoplasty with simultaneous cavernostomy and muscle transposition flap. ( 22446949 )
2012
47
Pulmonary aspergilloma: a potential cause of false positive fluorodeoxyglucose positron emission tomography scan. ( 22627956 )
2012
48
Pulmonary aspergilloma. ( 23409527 )
2012
49
Pulmonary aspergilloma: clinical aspects and surgical treatment outcome. ( 22789598 )
2012
50
Pulmonary aspergilloma with prominent oxalate deposition. ( 23455818 )
2012

Variations for Pulmonary Aspergilloma

Expression for Pulmonary Aspergilloma

Search GEO for disease gene expression data for Pulmonary Aspergilloma.

Pathways for Pulmonary Aspergilloma

Pathways related to Pulmonary Aspergilloma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.1 CRP VEGFA

GO Terms for Pulmonary Aspergilloma

Sources for Pulmonary Aspergilloma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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