Pulmonary Coin Lesion

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Pulmonary Coin Lesion

MalaCards integrated aliases for Pulmonary Coin Lesion:

Name: Pulmonary Coin Lesion 12 15 17
Solitary Pulmonary Nodule 43 71
Coin Lesion of Lung 12 71
Coin Lesion Lung 12


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Disease Ontology 12 DOID:5364
MeSH 43 D003074
ICD10 32 R91.1
UMLS 71 C0009250 C2350019

Summaries for Pulmonary Coin Lesion

MalaCards based summary : Pulmonary Coin Lesion, also known as solitary pulmonary nodule, is related to pneumothorax and virus-associated trichodysplasia spinulosa, and has symptoms including hemoptysis An important gene associated with Pulmonary Coin Lesion is ACSM1 (Acyl-CoA Synthetase Medium Chain Family Member 1). The drugs Glutamic acid and Fluorodeoxyglucose F18 have been mentioned in the context of this disorder. Affiliated tissues include lung, breast and thyroid, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Pulmonary Coin Lesion

Diseases related to Pulmonary Coin Lesion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 pneumothorax 10.6
2 virus-associated trichodysplasia spinulosa 10.6
3 adenocarcinoma 10.5
4 lung cancer susceptibility 3 10.4
5 sclerosing hemangioma 10.3
6 lung disease 10.3
7 hemangioma 10.2
8 small cell cancer of the lung 10.2
9 leiomyosarcoma 10.2
10 bronchiolitis obliterans 10.2
11 bronchiolitis 10.2
12 pneumonia 10.2
13 acquired immunodeficiency syndrome 10.2
14 mucormycosis 10.2
15 sarcoidosis 1 10.1
16 dirofilariasis 10.1
17 immune deficiency disease 10.1
18 thymoma, familial 10.1
19 thymoma 10.1
20 pulmonary sclerosing hemangioma 10.1
21 lung lymphoma 10.1
22 rare tumor 10.1
23 silicosis 10.0
24 meningioma, radiation-induced 10.0
25 meningioma, familial 10.0
26 granulomatosis with polyangiitis 10.0
27 cryptogenic organizing pneumonia 10.0
28 lymphoma 10.0
29 pneumocystosis 10.0
30 spinal meningioma 10.0
31 pleural disease 10.0
32 kidney cancer 10.0
33 endometriosis 10.0
34 liposarcoma 10.0
35 secretory meningioma 10.0
36 lymphoplasmacyte-rich meningioma 10.0
37 bronchiolo-alveolar adenocarcinoma 10.0
38 amyloidosis 10.0
39 pulmonary emphysema 10.0
40 48,xyyy 10.0
41 pulmonary sequestration 10.0
42 aneurysm 10.0
43 rheumatoid arthritis 9.9
44 lung cancer 9.9
45 congenital heart defects, hamartomas of tongue, and polysyndactyly 9.9
46 osteogenic sarcoma 9.9
47 infective endocarditis 9.9
48 lung abscess 9.9
49 adenoid cystic carcinoma 9.9
50 pleurisy 9.9

Graphical network of the top 20 diseases related to Pulmonary Coin Lesion:

Diseases related to Pulmonary Coin Lesion

Symptoms & Phenotypes for Pulmonary Coin Lesion

UMLS symptoms related to Pulmonary Coin Lesion:


GenomeRNAi Phenotypes related to Pulmonary Coin Lesion according to GeneCards Suite gene sharing:

26 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.58 GLS
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.58 ACSM1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-13 9.58 GLS
4 Increased shRNA abundance (Z-score > 2) GR00366-A-133 9.58 GLS
5 Increased shRNA abundance (Z-score > 2) GR00366-A-149 9.58 GLS
6 Increased shRNA abundance (Z-score > 2) GR00366-A-16 9.58 ACSM1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.58 ACSM1
8 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.58 ACSM1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-191 9.58 ACSM1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-26 9.58 GLS
11 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.58 GLS
12 Increased shRNA abundance (Z-score > 2) GR00366-A-5 9.58 ACSM1 GLS
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.58 GLS
14 Increased shRNA abundance (Z-score > 2) GR00366-A-54 9.58 GLS
15 Increased shRNA abundance (Z-score > 2) GR00366-A-60 9.58 GLS
16 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.58 GLS
17 Increased shRNA abundance (Z-score > 2) GR00366-A-93 9.58 GLS

Drugs & Therapeutics for Pulmonary Coin Lesion

Drugs for Pulmonary Coin Lesion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 35)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Glutamic acid Approved, Nutraceutical Phase 2 56-86-0 33032
2 Fluorodeoxyglucose F18 Phase 2
3 Fluorides Phase 2
4 Protective Agents Phase 2
5 Deoxyglucose Phase 2
6 Radiopharmaceuticals Phase 2
7 Cariostatic Agents Phase 2
8 Technetium Tc 99m Aggregated Albumin Phase 2
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
Lidocaine Approved, Vet_approved 137-58-6 3676
Dexmedetomidine Approved, Vet_approved 113775-47-6 68602 5311068
Ropivacaine Approved 84057-95-4 71273 175805
Sufentanil Approved, Investigational 56030-54-7 41693
Methylene blue Approved, Investigational 61-73-4
15 Antiviral Agents
16 Anti-Infective Agents
17 interferons
18 Interferon-gamma
19 Anesthetics, Local
20 Neurotransmitter Agents
21 Adrenergic Agonists
22 Adrenergic alpha-2 Receptor Agonists
23 Narcotics
24 Adjuvants, Anesthesia
25 Analgesics, Non-Narcotic
26 Analgesics, Opioid
27 Anesthetics, General
28 Hypnotics and Sedatives
29 Anesthetics, Intravenous
30 Central Nervous System Depressants
31 Analgesics
32 Adrenergic Agents
33 Liver Extracts
34 Pharmaceutical Solutions
35 Anesthetics

Interventional clinical trials:

(show all 50)
# Name Status NCT ID Phase Drugs
1 Ultrathin Bronchoscopy for Solitary Pulmonary Nodules: A Randomised Pilot Trial Completed NCT02490059 Phase 4
2 A Pilot Prospective Study Evaluating the SPiN Drive(TM)Electromagnetic Tip Tracked Devices Used in Diagnostic Bronchoscopy Withdrawn NCT01389154 Phase 4
3 The NoTube Study: Evaluation of the Necessity of a Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection. Unknown status NCT00841750 Phase 3
5 Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach Using Peripheral Endobronchial Ultrasonography and Electromagnetic Navigation Bronchoscopy Completed NCT00925210 Phase 2
6 Intravenous Indocyanine Green for Localization of Intra-thoracic Lesions Completed NCT03097627 Phase 1, Phase 2 ICG Intervention
7 PET Imaging of Lung Cancer and Indeterminate Pulmonary Nodules With 18F-FSPG Suspended NCT02448225 Phase 2 Fluorine F 18 L-glutamate Derivative BAY94-9392
8 Thorakoskopische Handheld-SPECT Gesteuerte Ektomie Von Radioaktiv-markierten Pulmonalen Rundherden. Proof of Feasibility of Thoracoscopic Ectomy of Radioactively Marked Pulmonary Nodules With the Help of Free-hand SPECT. Terminated NCT02050724 Phase 2 Radioactive labelling of pulmonary nodules
9 Evaluate the Auxiliary Diagnostic Value of Circulating Tumor Cells(CTC) in Benign and Malignant Lung Nodules Unknown status NCT02653859
10 EBUS Guided Cryo Biopsy of Solitary Pulmonary Nodules Unknown status NCT01221493
11 Evaluate the Utility of the ProLung China Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer Unknown status NCT02726633
12 Usefulness of Interferon-gamma Release Assay in Diagnosing Pulmonary Nodules Unknown status NCT01149187
13 Thoracoscopic Surgery Without Chest Tube Placement in Patients With Peripheral Lung Nodules: A Prospective Randomized Trial Unknown status NCT02817048
14 the Safety and Effectiveness of the Effects on the Perioperative Pain Control Comparing Between the Thoracic Paravertebral Nerve Block Using the Camera Guided and the Intrathoracic Intercostals Nerve Block for the Management of Nonintubated Local Regional Analgesia in Uniport Thoracoscopic Surgery for the Undetermined Solitary Nodules Patients Unknown status NCT03086213 Propofol;Sulfentanyl;Dexmedetomidine;Lidocaine;Ropivacaine
15 Differentiation of Malig. & Ben. Solitary Pulm. Nodules & Prediction of Clin. Outcome Using Perfus. Analysis of DCEMRI Unknown status NCT00172575
16 Accuracy and Cost-Effectiveness of Dynamic Contrast Enhanced Computed Tomography in the Characterisation of Solitary Pulmonary Nodules Unknown status NCT02013063
17 Discrimination of Benign and Malignant Human Tissue During Percutaneous Interventions Using Optical Spectroscopy Techniques Completed NCT01730365
18 Evaluate the Utility of the ProLung Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer Completed NCT01958931
19 Feasibility Study of a Bronchoscopic Ultrasound-Guided Tissue Acquisition System With Real-time Visualization for Collection of Cytology Specimens of Peripheral Pulmonary Lesions Completed NCT02832284
20 A Multi-Center Trial of the ProLung Test™ (Transthoracic Bioconductance Measurement) as an Adjunct to CT Chest Scans for the Risk Stratification of Patients With Pulmonary Lesions Suspicious for Lung Cancer Completed NCT01566682
21 A Pilot Trial of Near Infrared Fluorescence Imaging With Indocyanine Green in the Detection and Diagnosis of Neoplastic Pulmonary Nodules Completed NCT02851368 Early Phase 1 Indocyanine Green
22 Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis Completed NCT02531646
23 Diagnostic Value of Electromagnetic Navigation Bronchoscopy With a Guide Sheath for Peripheral Pulmonary Lesions : a Randomized Controlled Trial Completed NCT02207478
24 GE Healthcare VolumeRAD Lung Nodule Detection Study Completed NCT00963651
25 Three-dimensionally Printed Navigational Template for Localizing Small Pulmonary Nodules Completed NCT04056923 Indocyanine Green;Methylene blue
26 Clinical Effectiveness of a Balloon Covered Sheath as a Guide Sheath in Endobronchial Ultrasound Guided Diagnosis of Peripheral Lung Lesions Completed NCT00922155
27 Assessment of Probe Based Confocal Laser Endo-microscopy for In-vivo Diagnosis of Peripheral Lung Nodules and Masses. "NODIVEM" Study Completed NCT01931579
28 An Un-blinded, Intra-patient Comparison of Transbronchial Forceps Biopsy and Cryobiopsy for Peripheral Pulmonary Lesions Recruiting NCT02983903
29 Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules Recruiting NCT04165603
30 [18F] 4-L-Fluoroglutamine (2S,4R) PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules Recruiting NCT03568799
31 TH-146: Cancer Associated Macrophage-Like (CAML) Cells to Enhance Detection of Early Stage Lung Cancer Recruiting NCT03992183
32 Is Bronchoscopy Necessary in the Preoperative Workup of Ground Glass Opacity Featured Lung Cancer? Recruiting NCT03591445
33 Lung Nodule Characterization by Artificial Intelligence Techniques Recruiting NCT03843164
34 A Clinical Application Study of a CT Guided Small Pulmonary Nodule Puncture and Positioning Device Based on Pre-filled Absorbable Semi-barbed Wire Recruiting NCT04168359
35 The Early Diagnosis of Pulmonary Nodule Based on Multi-dimension Messages Recruiting NCT04005677
36 Mobile Lung Nodule Observatory for Worldwide, Evidenced - Based Research Recruiting NCT02693496
37 Targeted Chromosomal Aberrations Detection by FISH Analysis of Circulating Abnormal Cells to Differentiate of Benign and Malignant Pulmonary Nodules Recruiting NCT03790735
38 Methylation of cfDNA in Diagnosing and Monitoring Benign and Malignant Pulmonary Nodule Recruiting NCT03989219
39 Feasibility of Single Exposure Dual Energy Subtraction With a Multi-Energy Digital Radiography Detector for Lung Lesions Detection Recruiting NCT03528733
40 A Clinical Study to Evaluate the Efficacy and Safety of A Optimized Computed Tomography-guided Pulmonary Nodule Microcoil Localization Technique Recruiting NCT03649906
41 Multi Center Clinical Study of Three Plus Two Type Early Diagnosis of Pulmonary Nodules in Medical Internet of Things Recruiting NCT02773992
42 Intraoperative, Percutaneous Localization of Peripheral Pulmonary Nodules for Resection: a Prospective, Open-Label, Multi-Center Registry Study of Thoracic Surgery Outcomes. Recruiting NCT04066699
43 IDEAL: Artificial Intelligence and Big Data for Early Lung Cancer Diagnosis Prospective Study (Phase 2) Recruiting NCT03753724
44 Multi-centers Validation of a Circulating Tumor DNA Assay to Differentiate Benign and Malignant Pulmonary Nodules Via Targeted High-throughput DNA Methylation Sequencing Active, not recruiting NCT03181490
45 The Watch the Spot Trial: A Pragmatic Trial of More Versus Less Intensive Strategies for Active Surveillance of Patients With Small Pulmonary Nodules Enrolling by invitation NCT02623712
46 Incidence and Significance of Extracolonic Findings on CT Colonography: Retrospective Analysis of "National CT Colonography Trial" Data Enrolling by invitation NCT01465425
47 Pulmonary Nodule Cohort Not yet recruiting NCT04049422
48 Evaluation of the Archimedes ™ System for Transparenchymatous Access to Pulmonary Nodules. Not yet recruiting NCT04140474
49 Evaluation of Lung Nodule and Lung Cancer Detection With Artificial Intelligence Assisted Computed Tomography Among People Living in North China: a Prospective Single-arm Multicentre Study of Screening Not yet recruiting NCT03487952
50 Clinical Evaluation of Primary Sampling Scatter Correction for Chest Tomosynthesis Not yet recruiting NCT04076696

Search NIH Clinical Center for Pulmonary Coin Lesion

Cochrane evidence based reviews: solitary pulmonary nodule

Genetic Tests for Pulmonary Coin Lesion

Anatomical Context for Pulmonary Coin Lesion

MalaCards organs/tissues related to Pulmonary Coin Lesion:

Lung, Breast, Thyroid, Testes, Heart, Liver, B Cells

Publications for Pulmonary Coin Lesion

Articles related to Pulmonary Coin Lesion:

(show top 50) (show all 980)
# Title Authors PMID Year
Olfactory neuroblastoma pulmonary metastasis presenting as a solitary pulmonary mass in an adult: A case report with pathologic correlation. 61
31993094 2020
Evaluation of the diagnostic efficacy of 18 F-Fluorine-2-Deoxy-D-Glucose PET/CT for lung cancer and pulmonary tuberculosis in a Tuberculosis-endemic Country. 61
31837121 2020
Solitary Pulmonary Nodule as a Form of Presentation of Cryptococcosis in a Renal Transplant Recipient. 61
31926752 2020
Interobserver agreement of the visual Herder scale for the assessment of solitary pulmonary nodules on 18F Fluorodeoxyglucose PET/computed tomography. 61
31923048 2020
Ciliated Muconodular Papillary Tumor of the Lung: Thin-Section CT Findings of 16 Cases. 61
31967497 2020
Pre-surgical lung biopsy in management of solitary pulmonary nodules: a cost effectiveness analysis. 61
31490717 2019
The Necessity of Anti-Tuberculosis Therapy after Resection of Pulmonary Tuberculous Nodules: A Single Center Retrospective Study. 61
31776302 2019
Solitary pulmonary nodules caused by Mycobacterium avium complex. 61
31402330 2019
Coexistence of nontuberculous mycobacterium and IgG4-related disease in a solitary pulmonary nodule: A case report. 61
31770270 2019
Pathophysiology of acute fibrinous and organizing pneumonia - Clinical and morphological spectra. 61
31076239 2019
Solitary Pulmonary Nodule: Morphological Effects on Metabolic Activity Assessment 61
31507144 2019
Arterial Gas Embolism: A Rare Complication of Core Needle Biopsy in the Diagnosis of Solitary Pulmonary Nodule. 61
30890288 2019
Radial probe endobronchial ultrasound (R-EBUS) guided transbronchial cryobiopsy in the diagnosis of peripheral solitary pulmonary nodule. 61
31424050 2019
Diagnosis and management of peripheral lung nodule. 61
31516894 2019
Using neighborhood gray tone difference matrix texture features on dual time point PET/CT images to differentiate malignant from benign FDG-avid solitary pulmonary nodules. 61
31420006 2019
PET Counting Response Variability Depending on Tumor Location, Activity, and Patient Obesity: A Feasibility Study of Solitary Pulmonary Nodule Using Monte Carlo. 61
30629497 2019
Management of the solitary pulmonary nodule. 61
30973358 2019
Post-tuberculosis Pneumocytoma. 61
31133161 2019
Ipsilateral Hyperhidrosis: Atypical Symptom of Small Lung Adenocarcinoma Evaluated by 18F-FDG PET-CT. 61
31231444 2019
Solitary pulmonary nodule: Comparison of quantitative capability for differentiation and management among dynamic CE-perfusion MRI at 3 T system, dynamic CE-perfusion ADCT and FDG-PET/CT. 61
31084755 2019
Comparing attenuations of malignant and benign solitary pulmonary nodule using semi-automated region of interest selection on contrast-enhanced CT. 61
31372276 2019
Symptomatic pulmonary sclerosing hemangioma: a rare case of a solitary pulmonary nodule in a woman of advanced age. 61
30971157 2019
Prevalence of pulmonary nodules in dogs with malignant neoplasia as determined by CT. 61
30784158 2019
Update on radioguided surgery: from international consensus on sentinel node in head and neck cancer to the advances on gynaecological tumors and localization of non-palpable lesions. 61
30579916 2019
Correlation study between dual source CT perfusion imaging and the microvascular composition of solitary pulmonary nodules. 61
30885331 2019
Development and validation of a predictive model for the diagnosis of solid solitary pulmonary nodules using data mining methods. 61
31019785 2019
Evaluation of the solitary pulmonary nodule. 61
30897667 2019
Solitary Nodular Invasive Mucinous Adenocarcinoma of the Lung: Imaging Diagnosis Using the Morphologic-Metabolic Dissociation Sign. 61
30799583 2019
Diagnosing a solitary pulmonary nodule using multiple bronchoscopic guided technologies: A prospective randomized study. 61
30797491 2019
[Health economics analysis for 18F-fluorodeoxyglucose positron-emission tomography compared with computed tomography in lung cancer]. 61
30837392 2019
The clincopathological variables to differentiate the nature of isolated pulmonary nodules in patients who received curative surgery for colorectal cancer. 61
30262438 2019
Interventional therapy in patients with severe emphysema: evaluation of contraindications and their incidence. 61
30874483 2019
Is 18F-Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography useful to discriminate metachronous lung cancer from metastasis in patients with oncological history? 61
30654605 2019
[Combination of CT mulitplane 3D reconstruction, radial endobronchial ultrasound and rapid on-site evaluation for diagnosing peripheral solitary pulmonary nodules]. 61
30669745 2019
Methylation of RUNX3 and RASSF1A and the risk of Malignancy in small solitary pulmonary nodules. 61
31436249 2019
The determinants of lung cancer after detecting a solitary pulmonary nodule are different in men and women, for both chest radiograph and CT. 61
31509550 2019
Development and Validation of a Prediction Pneumothorax Model in CT-Guided Transthoracic Needle Biopsy for Solitary Pulmonary Nodule. 61
31192257 2019
Safety and efficacy of computed tomography-guided dye localization using patent blue V for single lung nodule for video-assisted thoracoscopic surgery: a retrospective study. 61
30854381 2019
PET/CT Findings of Granulomatosis With Polyangiitis Presenting as a Solitary Pulmonary Nodule and Mimicking Lung Cancer. 61
30664544 2019
Solitary Pulmonary Nodule: A Diagnostic Dilemma. 61
31871812 2019
Rare Primary Pulmonary Marginal Zone Lymphoma Presenting with Incidental Pulmonary Nodules. 61
31016061 2019
Surgical resection is sufficient for incidentally discovered solitary pulmonary nodule caused by nontuberculous mycobacteria in asymptomatic patients. 61
31513659 2019
Solitary pulmonary nodule: An interesting clinical mimicry of pulmonary tuberculosis. 61
30705491 2019
An interesting case of incidental solitary pulmonary nodule. 61
30820253 2018
Clinical prediction of solitary pulmonary nodule after a curative resection for gastric cancer. 61
30321372 2018
Primary Pulmonary Chordoid Meningioma. 61
30588452 2018
Primary pulmonary meningioma mimicking lung metastatic tumor: a case report. 61
30285886 2018
Interventional Pulmonology and Solitary Pulmonary Nodule. 61
29580566 2018
Performance of FDG-PET/CT in solitary pulmonary nodule based on pre-test likelihood of malignancy: results from the ITALIAN retrospective multicenter trial. 61
29736699 2018
Risk-related 18F-FDG PET/CT and new diagnostic strategies in patients with solitary pulmonary nodule: the ITALIAN multicenter trial. 61
29730697 2018

Variations for Pulmonary Coin Lesion

Expression for Pulmonary Coin Lesion

Search GEO for disease gene expression data for Pulmonary Coin Lesion.

Pathways for Pulmonary Coin Lesion

GO Terms for Pulmonary Coin Lesion

Biological processes related to Pulmonary Coin Lesion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemotaxis GO:0006935 9.16 FPR1 FLT1
2 cholesterol homeostasis GO:0042632 8.96 EPHX2 ACSM1
3 xenobiotic metabolic process GO:0006805 8.62 EPHX2 ACSM1

Sources for Pulmonary Coin Lesion

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
54 Novoseek
57 OMIM via Orphanet
61 PubMed
70 Tocris
72 UMLS via Orphanet
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