MCID: PLM028
MIFTS: 33

Pulmonary Coin Lesion

Categories: Cancer diseases, Respiratory diseases

Aliases & Classifications for Pulmonary Coin Lesion

MalaCards integrated aliases for Pulmonary Coin Lesion:

Name: Pulmonary Coin Lesion 12 15 17
Solitary Pulmonary Nodule 43 71
Coin Lesion of Lung 12 71
Coin Lesion Lung 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5364
MeSH 43 D003074
SNOMED-CT 67 308689002
ICD10 32 R91.1
UMLS 71 C0009250 C2350019

Summaries for Pulmonary Coin Lesion

MalaCards based summary : Pulmonary Coin Lesion, also known as solitary pulmonary nodule, is related to pneumothorax and virus-associated trichodysplasia spinulosa, and has symptoms including hemoptysis An important gene associated with Pulmonary Coin Lesion is SPESP1 (Sperm Equatorial Segment Protein 1), and among its related pathways/superpathways is Ras signaling pathway. The drugs Glutamic acid and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and breast.

Related Diseases for Pulmonary Coin Lesion

Diseases related to Pulmonary Coin Lesion via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 pneumothorax 10.6
2 virus-associated trichodysplasia spinulosa 10.6
3 adenocarcinoma 10.5
4 lung cancer susceptibility 3 10.4
5 lung cancer 10.4
6 sclerosing hemangioma 10.3
7 lung disease 10.3
8 hemangioma 10.2
9 small cell cancer of the lung 10.2
10 leiomyosarcoma 10.2
11 bronchiolitis obliterans 10.2
12 bronchiolitis 10.2
13 acquired immunodeficiency syndrome 10.2
14 mucormycosis 10.2
15 immune deficiency disease 10.1
16 thymoma, familial 10.1
17 thymoma 10.1
18 pneumonia 10.1
19 pulmonary sclerosing hemangioma 10.1
20 lung lymphoma 10.1
21 rare tumor 10.1
22 sarcoidosis 1 10.1
23 dirofilariasis 10.1
24 meningioma, radiation-induced 10.0
25 meningioma, familial 10.0
26 granulomatosis with polyangiitis 10.0
27 cryptogenic organizing pneumonia 10.0
28 lymphoma 10.0
29 pneumocystosis 10.0
30 spinal meningioma 10.0
31 pleural disease 10.0
32 kidney cancer 10.0
33 endometriosis 10.0
34 liposarcoma 10.0
35 secretory meningioma 10.0
36 lymphoplasmacyte-rich meningioma 10.0
37 bronchiolo-alveolar adenocarcinoma 10.0
38 amyloidosis 10.0
39 pulmonary emphysema 10.0
40 48,xyyy 10.0
41 pulmonary sequestration 10.0
42 aneurysm 10.0
43 silicosis 10.0
44 breast cancer 9.9
45 renal cell carcinoma, nonpapillary 9.9
46 leiomyoma, uterine 9.9
47 thyroid carcinoma, familial medullary 9.9
48 pneumothorax, primary spontaneous 9.9
49 pulmonary fibrosis, idiopathic 9.9
50 pulmonary nodular lymphoid hyperplasia, familial 9.9

Graphical network of the top 20 diseases related to Pulmonary Coin Lesion:



Diseases related to Pulmonary Coin Lesion

Symptoms & Phenotypes for Pulmonary Coin Lesion

UMLS symptoms related to Pulmonary Coin Lesion:


hemoptysis

Drugs & Therapeutics for Pulmonary Coin Lesion

Drugs for Pulmonary Coin Lesion (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 38)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Glutamic acid Approved, Nutraceutical Phase 2 56-86-0 33032
2 Anti-Infective Agents Phase 2
3 Fluorides Phase 2
4 Antiviral Agents Phase 2
5 Protective Agents Phase 2
6 Deoxyglucose Phase 2
7 Antimetabolites Phase 2
8 Technetium Tc 99m Aggregated Albumin Phase 2
9 Radiopharmaceuticals Phase 2
10
Dexmedetomidine Approved, Vet_approved 113775-47-6 5311068 68602
11
Propofol Approved, Investigational, Vet_approved 2078-54-8 4943
12
Lidocaine Approved, Vet_approved 137-58-6 3676
13
Sufentanil Approved, Investigational 56030-54-7 41693
14
Ropivacaine Approved 84057-95-4 71273 175805
15
Methylene blue Approved, Investigational 61-73-4
16
Nitrous oxide Approved, Vet_approved 10024-97-2 948
17 interferons
18 Interferon-gamma
19 Liver Extracts
20 Adrenergic alpha-Agonists
21 Sodium Channel Blockers
22 Narcotics
23 Hypnotics and Sedatives
24 Adrenergic Agents
25 Anti-Arrhythmia Agents
26 Analgesics, Opioid
27 Anesthetics, Local
28 Adrenergic Agonists
29 Anesthetics, Intravenous
30 Diuretics, Potassium Sparing
31 Neurotransmitter Agents
32 Analgesics
33 Analgesics, Non-Narcotic
34 Anesthetics, General
35 Pharmaceutical Solutions
36 Anesthetics, Inhalation
37 Fluorodeoxyglucose F18
38 Anesthetics

Interventional clinical trials:

(show top 50) (show all 54)
# Name Status NCT ID Phase Drugs
1 Ultrathin Bronchoscopy for Solitary Pulmonary Nodules: A Randomised Pilot Trial Completed NCT02490059 Phase 4
2 A Pilot Prospective Study Evaluating the SPiN Drive(TM)Electromagnetic Tip Tracked Devices Used in Diagnostic Bronchoscopy Withdrawn NCT01389154 Phase 4
3 The NoTube Study: Evaluation of the Necessity of a Chest Tube After a Video-assisted Thoracoscopic Surgery Pulmonary Wedge Resection. Unknown status NCT00841750 Phase 3
4 18/F-FLUORODEOXYGLUCOSE (FDG) POSITRON EMISSION TOMOGRAPHY (PET) IMAGING IN THE MANAGEMENT OF PATIENTS WITH SOLITARY PULMONARY NODULES Completed NCT00032331 Phase 3
5 Bronchoscopic Approach to the Peripheral Lung Nodule - An Alternative Approach Using Peripheral Endobronchial Ultrasonography and Electromagnetic Navigation Bronchoscopy Completed NCT00925210 Phase 2
6 Intravenous Indocyanine Green for Localization of Intra-thoracic Lesions Completed NCT03097627 Phase 1, Phase 2 ICG Intervention
7 PET Imaging of Lung Cancer and Indeterminate Pulmonary Nodules With 18F-FSPG Recruiting NCT02448225 Phase 2 Fluorine F 18 L-glutamate Derivative BAY94-9392
8 Thorakoskopische Handheld-SPECT Gesteuerte Ektomie Von Radioaktiv-markierten Pulmonalen Rundherden. Proof of Feasibility of Thoracoscopic Ectomy of Radioactively Marked Pulmonary Nodules With the Help of Free-hand SPECT. Terminated NCT02050724 Phase 2 Radioactive labelling of pulmonary nodules
9 Evaluate the Auxiliary Diagnostic Value of Circulating Tumor Cells(CTC) in Benign and Malignant Lung Nodules Unknown status NCT02653859
10 EBUS Guided Cryo Biopsy of Solitary Pulmonary Nodules Unknown status NCT01221493
11 Evaluate the Utility of the ProLung China Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer Unknown status NCT02726633
12 Usefulness of Interferon-gamma Release Assay in Diagnosing Pulmonary Nodules Unknown status NCT01149187
13 Thoracoscopic Surgery Without Chest Tube Placement in Patients With Peripheral Lung Nodules: A Prospective Randomized Trial Unknown status NCT02817048
14 Differentiation of Malig. & Ben. Solitary Pulm. Nodules & Prediction of Clin. Outcome Using Perfus. Analysis of DCEMRI Unknown status NCT00172575
15 Accuracy and Cost-Effectiveness of Dynamic Contrast Enhanced Computed Tomography in the Characterisation of Solitary Pulmonary Nodules Unknown status NCT02013063
16 Discrimination of Benign and Malignant Human Tissue During Percutaneous Interventions Using Optical Spectroscopy Techniques Completed NCT01730365
17 Evaluate the Utility of the ProLung Test as Adjunctive to CT Scan in the Diagnosis of Lung Cancer Completed NCT01958931
18 A Multi-Center Trial of the ProLung Test™ (Transthoracic Bioconductance Measurement) as an Adjunct to CT Chest Scans for the Risk Stratification of Patients With Pulmonary Lesions Suspicious for Lung Cancer Completed NCT01566682
19 Feasibility Study of a Bronchoscopic Ultrasound-Guided Tissue Acquisition System With Real-time Visualization for Collection of Cytology Specimens of Peripheral Pulmonary Lesions Completed NCT02832284
20 the Safety and Effectiveness of the Effects on the Perioperative Pain Control Comparing Between the Thoracic Paravertebral Nerve Block Using the Camera Guided and the Intrathoracic Intercostals Nerve Block for the Management of Nonintubated Local Regional Analgesia in Uniport Thoracoscopic Surgery for the Undetermined Solitary Nodules Patients Completed NCT03086213 Propofol;Sulfentanyl;Dexmedetomidine;Lidocaine;Ropivacaine
21 Multi-centers Validation of a Circulating Tumor DNA Assay to Differentiate Benign and Malignant Pulmonary Nodules Via Targeted High-throughput DNA Methylation Sequencing Completed NCT03181490
22 Diagnostic Value of Electromagnetic Navigation Bronchoscopy With a Guide Sheath for Peripheral Pulmonary Lesions : a Randomized Controlled Trial Completed NCT02207478
23 GE Healthcare VolumeRAD Lung Nodule Detection Study Completed NCT00963651
24 Clinical Evaluation of CARESTREAM Dual Energy and Digital Tomosynthesis Completed NCT02531646
25 A Pilot Trial of Near Infrared Fluorescence Imaging With Indocyanine Green in the Detection and Diagnosis of Neoplastic Pulmonary Nodules Completed NCT02851368 Early Phase 1 Indocyanine Green
26 Three-dimensionally Printed Navigational Template for Localizing Small Pulmonary Nodules Completed NCT04056923 Indocyanine Green;Methylene blue
27 Clinical Effectiveness of a Balloon Covered Sheath as a Guide Sheath in Endobronchial Ultrasound Guided Diagnosis of Peripheral Lung Lesions Completed NCT00922155
28 The Benefit of Ultra-high Resolution Computed Tomography: Precision of Repeated Volume Measurements of Pulmonary Nodules Completed NCT04209972
29 Assessment of Probe Based Confocal Laser Endo-microscopy for In-vivo Diagnosis of Peripheral Lung Nodules and Masses. "NODIVEM" Study Completed NCT01931579
30 Fluorescence-navigated Thoracoscopy for Detection of Small Pulmonary Nodules Recruiting NCT04165603
31 [18F] 4-L-Fluoroglutamine (2S,4R) PET/CT in Imaging Patients With Newly Diagnosed Lung Cancer or Indeterminate Pulmonary Nodules Recruiting NCT03568799
32 TH-146: Cancer Associated Macrophage-Like (CAML) Cells to Enhance Detection of Early Stage Lung Cancer Recruiting NCT03992183
33 Is Bronchoscopy Necessary in the Preoperative Workup of Ground Glass Opacity Featured Lung Cancer? Recruiting NCT03591445
34 A Clinical Application Study of a CT Guided Small Pulmonary Nodule Puncture and Positioning Device Based on Pre-filled Absorbable Semi-barbed Wire Recruiting NCT04168359
35 The Early Diagnosis of Pulmonary Nodule Based on Multi-dimension Messages Recruiting NCT04005677
36 Lung Nodule Characterization by Artificial Intelligence Techniques Recruiting NCT03843164
37 Mobile Lung Nodule Observatory for Worldwide, Evidenced - Based Research Recruiting NCT02693496
38 Methylation of cfDNA in Diagnosing and Monitoring Benign and Malignant Pulmonary Nodule Recruiting NCT03989219
39 Targeted Chromosomal Aberrations Detection by FISH Analysis of Circulating Abnormal Cells to Differentiate of Benign and Malignant Pulmonary Nodules Recruiting NCT03790735
40 Feasibility of Single Exposure Dual Energy Subtraction With a Multi-Energy Digital Radiography Detector for Lung Lesions Detection Recruiting NCT03528733
41 A Clinical Study to Evaluate the Efficacy and Safety of A Optimized Computed Tomography-guided Pulmonary Nodule Microcoil Localization Technique Recruiting NCT03649906
42 Multi Center Clinical Study of Three Plus Two Type Early Diagnosis of Pulmonary Nodules in Medical Internet of Things Recruiting NCT02773992
43 Intraoperative, Percutaneous Localization of Peripheral Pulmonary Nodules for Resection: a Prospective, Open-Label, Multi-Center Registry Study of Thoracic Surgery Outcomes. Recruiting NCT04066699
44 Application of Nitrous Oxide in Inflation-deflation Process During Thoracoscopic Segmentectomy: A Randomized Double-Blind, Parallel Controlled Study Recruiting NCT04302350
45 IDEAL: Artificial Intelligence and Big Data for Early Lung Cancer Diagnosis Prospective Study (Phase 2) Recruiting NCT03753724
46 The Watch the Spot Trial: A Pragmatic Trial of More Versus Less Intensive Strategies for Active Surveillance of Patients With Small Pulmonary Nodules Enrolling by invitation NCT02623712
47 Incidence and Significance of Extracolonic Findings on CT Colonography: Retrospective Analysis of "National CT Colonography Trial" Data Enrolling by invitation NCT01465425
48 Pulmonary Nodule Cohort Not yet recruiting NCT04049422
49 Lung Nodule Imaging Biobank for Radiomics and AI Research Not yet recruiting NCT04270799
50 Evaluation of the Archimedes ™ System for Transparenchymatous Access to Pulmonary Nodules. Not yet recruiting NCT04140474

Search NIH Clinical Center for Pulmonary Coin Lesion

Cochrane evidence based reviews: solitary pulmonary nodule

Genetic Tests for Pulmonary Coin Lesion

Anatomical Context for Pulmonary Coin Lesion

MalaCards organs/tissues related to Pulmonary Coin Lesion:

40
Lung, Testes, Breast, Liver, Thyroid, Lymph Node, Prostate

Publications for Pulmonary Coin Lesion

Articles related to Pulmonary Coin Lesion:

(show top 50) (show all 1000)
# Title Authors PMID Year
1
68Ga-FAPI PET/CT Improves Therapeutic Strategy by Detecting a Second Primary Malignancy in a Patient With Rectal Cancer. 61
32149789 2020
2
Solitary Pulmonary Nodule as a Form of Presentation of Cryptococcosis in a Renal Transplant Recipient. 61
31926752 2020
3
Combination of 1.1 mm flexible cryoprobe with conventional guide sheath and therapeutic bronchoscope in biopsy of apical upper lobe solitary pulmonary nodule. 61
32493437 2020
4
Olfactory neuroblastoma pulmonary metastasis presenting as a solitary pulmonary mass in an adult: A case report with pathologic correlation. 61
31993094 2020
5
Outcome of PET-Negative Solid Pulmonary Nodules: A Retrospective Study. 61
32303444 2020
6
Ciliated Muconodular Papillary Tumor of the Lung: Thin-Section CT Findings of 16 Cases. 61
31967497 2020
7
Differences in the clinical management of women and men after detection of a solitary pulmonary nodule in clinical practice. 61
32193639 2020
8
Interobserver agreement of the visual Herder scale for the assessment of solitary pulmonary nodules on 18F Fluorodeoxyglucose PET/computed tomography. 61
31923048 2020
9
Towards more accurate 18F-fluorodeoxyglucose positron emission tomography (18F-FDG PET) imaging in active and latent tuberculosis. 61
32114199 2020
10
PET/CT and the solitary pulmonary nodule. 61
32336834 2020
11
An 80-Year-Old Woman With a Solitary Pulmonary Nodule. 61
32145822 2020
12
Diagnosis and management of glandular papilloma of lung: A case report. 61
32258080 2020
13
A case of a primary pulmonary meningioma mimicking a metastasis from a papillary thyroid carcinoma due to a size reduction after radioactive iodine therapy. 61
32221747 2020
14
[Clinical analysis of 30 cases of Castleman disease with different types of thoracic involvement]. 61
32135633 2020
15
An ectopic Cushing's syndrome as a cause of severe refractory hypokalemia in the ICU. 61
32089125 2020
16
Evaluation of the diagnostic efficacy of 18 F-Fluorine-2-Deoxy-D-Glucose PET/CT for lung cancer and pulmonary tuberculosis in a Tuberculosis-endemic Country. 61
31837121 2020
17
[Prognosis factors analysis of patients with malignant solitary pulmonary nodules]. 61
32071480 2020
18
Use of PET/CT to aid clinical decision-making in cases of solitary pulmonary nodule: a probabilistic approach. 61
32313329 2020
19
A Veteran With a Solitary Pulmonary Nodule. 61
32047354 2020
20
[Multiple insufficiency fractures (metatarsial, calcaneal and sacral) as the first manifestation of lung adenocarcinoma. A case report and literature review]. 61
32441259 2020
21
Metastatic Breast Cancer Coexisting With HER-2 Amplification and EGFR Exon 19 Deletion Benefits From EGFR-TKI Therapy: A Case Report. 61
32547945 2020
22
Role of Computed Tomography-guided Biopsies in the Era of Electromagnetic Navigational Bronchoscopy: A Retrospective Study of Factors Predicting Diagnostic Yield in Electromagnetic Navigational Bronchoscopy and Computed Tomography Biopsies. 61
32547836 2020
23
Pulmonary Hyalinizing Granuloma Mimicking Primary Lung Cancer: An Unusual Case Involving a Pulmonary Tumor. 61
32082681 2020
24
[Lung cancer diagnosed by transesophageal ecoendoscopy and fine needle aspiration biopsy]. 61
32282326 2020
25
[Surgical Resection of a Solitary Pulmonary Nodule in a Patient with Breast Cancer-A Case Report]. 61
32157067 2019
26
Pre-surgical lung biopsy in management of solitary pulmonary nodules: a cost effectiveness analysis. 61
31490717 2019
27
The Necessity of Anti-Tuberculosis Therapy after Resection of Pulmonary Tuberculous Nodules: A Single Center Retrospective Study. 61
31776302 2019
28
Solitary pulmonary nodules caused by Mycobacterium avium complex. 61
31402330 2019
29
Coexistence of nontuberculous mycobacterium and IgG4-related disease in a solitary pulmonary nodule: A case report. 61
31770270 2019
30
Solitary Pulmonary Nodule: Morphological Effects on Metabolic Activity Assessment 61
31507144 2019
31
Pathophysiology of acute fibrinous and organizing pneumonia - Clinical and morphological spectra. 61
31076239 2019
32
Arterial Gas Embolism: A Rare Complication of Core Needle Biopsy in the Diagnosis of Solitary Pulmonary Nodule. 61
30890288 2019
33
Radial probe endobronchial ultrasound (R-EBUS) guided transbronchial cryobiopsy in the diagnosis of peripheral solitary pulmonary nodule. 61
31424050 2019
34
Diagnosis and management of peripheral lung nodule. 61
31516894 2019
35
Using neighborhood gray tone difference matrix texture features on dual time point PET/CT images to differentiate malignant from benign FDG-avid solitary pulmonary nodules. 61
31420006 2019
36
PET Counting Response Variability Depending on Tumor Location, Activity, and Patient Obesity: A Feasibility Study of Solitary Pulmonary Nodule Using Monte Carlo. 61
30629497 2019
37
Management of the solitary pulmonary nodule. 61
30973358 2019
38
Post-tuberculosis Pneumocytoma. 61
31133161 2019
39
Ipsilateral Hyperhidrosis: Atypical Symptom of Small Lung Adenocarcinoma Evaluated by 18F-FDG PET-CT. 61
31231444 2019
40
Solitary pulmonary nodule: Comparison of quantitative capability for differentiation and management among dynamic CE-perfusion MRI at 3 T system, dynamic CE-perfusion ADCT and FDG-PET/CT. 61
31084755 2019
41
Comparing attenuations of malignant and benign solitary pulmonary nodule using semi-automated region of interest selection on contrast-enhanced CT. 61
31372276 2019
42
Symptomatic pulmonary sclerosing hemangioma: a rare case of a solitary pulmonary nodule in a woman of advanced age. 61
30971157 2019
43
Prevalence of pulmonary nodules in dogs with malignant neoplasia as determined by CT. 61
30784158 2019
44
Update on radioguided surgery: from international consensus on sentinel node in head and neck cancer to the advances on gynaecological tumors and localization of non-palpable lesions. 61
30579916 2019
45
Correlation study between dual source CT perfusion imaging and the microvascular composition of solitary pulmonary nodules. 61
30885331 2019
46
Development and validation of a predictive model for the diagnosis of solid solitary pulmonary nodules using data mining methods. 61
31019785 2019
47
Diagnosing a solitary pulmonary nodule using multiple bronchoscopic guided technologies: A prospective randomized study. 61
30797491 2019
48
Evaluation of the solitary pulmonary nodule. 61
30897667 2019
49
Solitary Nodular Invasive Mucinous Adenocarcinoma of the Lung: Imaging Diagnosis Using the Morphologic-Metabolic Dissociation Sign. 61
30799583 2019
50
[Health economics analysis for 18F-fluorodeoxyglucose positron-emission tomography compared with computed tomography in lung cancer]. 61
30837392 2019

Variations for Pulmonary Coin Lesion

Expression for Pulmonary Coin Lesion

Search GEO for disease gene expression data for Pulmonary Coin Lesion.

Pathways for Pulmonary Coin Lesion

Pathways related to Pulmonary Coin Lesion according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.27 FPR1 FLT1

GO Terms for Pulmonary Coin Lesion

Biological processes related to Pulmonary Coin Lesion according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemotaxis GO:0006935 8.62 FPR1 FLT1

Sources for Pulmonary Coin Lesion

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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