MCID: PLM015
MIFTS: 17

Pulmonary Systemic Sclerosis

Categories: Immune diseases, Respiratory diseases

Aliases & Classifications for Pulmonary Systemic Sclerosis

MalaCards integrated aliases for Pulmonary Systemic Sclerosis:

Name: Pulmonary Systemic Sclerosis 12 15
Lung Involvement in Systemic Sclerosis 12
Lung Disease with Systemic Sclerosis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1578
ICD10 33 M34.81
ICD9CM 35 517.2
SNOMED-CT 68 196133001
UMLS 73 C0339904

Summaries for Pulmonary Systemic Sclerosis

MalaCards based summary : Pulmonary Systemic Sclerosis, also known as lung involvement in systemic sclerosis, is related to scleroderma, familial progressive and interstitial lung disease. An important gene associated with Pulmonary Systemic Sclerosis is GDF15 (Growth Differentiation Factor 15). Affiliated tissues include lung.

Related Diseases for Pulmonary Systemic Sclerosis

Diseases related to Pulmonary Systemic Sclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 scleroderma, familial progressive 9.7
2 interstitial lung disease 9.7
3 lung disease 9.7

Symptoms & Phenotypes for Pulmonary Systemic Sclerosis

Drugs & Therapeutics for Pulmonary Systemic Sclerosis

Search Clinical Trials , NIH Clinical Center for Pulmonary Systemic Sclerosis

Genetic Tests for Pulmonary Systemic Sclerosis

Anatomical Context for Pulmonary Systemic Sclerosis

MalaCards organs/tissues related to Pulmonary Systemic Sclerosis:

41
Lung

Publications for Pulmonary Systemic Sclerosis

Articles related to Pulmonary Systemic Sclerosis:

# Title Authors Year
1
Growth differentiation factor 15, a marker of lung involvement in systemic sclerosis, is involved in fibrosis development but is not indispensable for fibrosis development. ( 24504814 )
2014
2
Lung involvement in systemic sclerosis sine scleroderma treated by plasma exchange. ( 1516994 )
1992

Variations for Pulmonary Systemic Sclerosis

Expression for Pulmonary Systemic Sclerosis

LifeMap Discovery
Genes differentially expressed in tissues of Pulmonary Systemic Sclerosis patients vs. healthy controls: 35
# Gene Description Tissue Up/Dn Fold Change (log2) P value
1 DEFA1 defensin, alpha 1 Lung - 3.15 0.000
Search GEO for disease gene expression data for Pulmonary Systemic Sclerosis.

Pathways for Pulmonary Systemic Sclerosis

GO Terms for Pulmonary Systemic Sclerosis

Sources for Pulmonary Systemic Sclerosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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