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MCID: PLM022
MIFTS: 37

Pulmonary Valve Insufficiency

Categories: Cardiovascular diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Pulmonary Valve Insufficiency

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MalaCards integrated aliases for Pulmonary Valve Insufficiency:

Name: Pulmonary Valve Insufficiency 12 44 15 73
Pulmonary Regurgitation 12 55
Pulmonary Insufficiency Following Trauma and Surgery 12
Pulmonary Incompetence, Non-Rheumatic 12
Pulmonic Valve Regurgitation 12
Pulmonary Incompetence 12
Pulmonic Insufficiency 12
Pulmonary Regurg. 12

Classifications:

MalaCards categories:
Anatomical: Cardiovascular diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:14265
MeSH 44 D011665
SNOMED-CT 68 91434003
ICD10 33 I37.1
UMLS 73 C0034088
Sources

Summaries for Pulmonary Valve Insufficiency

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Disease Ontology : 12 A pulmonary valve disease that occurs when the pulmonary valve is not strong enough to prevent backflow into the right ventricle. If it is secondary to pulmonary hypertension it is referred to as a Graham Steell murmur.

MalaCards based summary : Pulmonary Valve Insufficiency, also known as pulmonary regurgitation, is related to tricuspid valve stenosis and ventricular septal defect. An important gene associated with Pulmonary Valve Insufficiency is NPPB (Natriuretic Peptide B), and among its related pathways/superpathways is Benzodiazepine Pathway, Pharmacodynamics. The drugs Cilastatin and Meropenem have been mentioned in the context of this disorder. Affiliated tissues include heart, testes and lung.

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Related Diseases for Pulmonary Valve Insufficiency

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Diseases in the Pulmonary Valve Disease family:

Pulmonary Valve Insufficiency

Diseases related to Pulmonary Valve Insufficiency via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 tricuspid valve stenosis 30.0 NKX2-6 SLC6A11
2 ventricular septal defect 29.9 NKX2-6 NPPB
3 patent ductus arteriosus 1 29.9 NKX2-6 NPPB
4 respiratory failure 11.3
5 rheumatic pulmonary valve disease 11.2
6 pulmonary valve agenesis-intact ventricular septum-persistent ductus arteriosus syndrome 10.4
7 pulmonary valve agenesis-tetralogy of fallot-absence of ductus arteriosus syndrome 10.4
8 ebstein anomaly 10.1 NKX2-6 NPPB
9 tricuspid valve disease 10.1 NKX2-6 NPPB
10 heart valve disease 10.1 NKX2-6 NPPB
11 tetralogy of fallot 10.1
12 hypoplastic left heart syndrome 10.1 NKX2-6 NPPB
13 dextro-looped transposition of the great arteries 10.1 LEFTY2 NKX2-6
14 aortic valve disease 2 10.0 NKX2-6 NPPB
15 heart disease 10.0
16 wernicke-korsakoff syndrome 10.0 KIAA0753 LEFTY2
17 pulmonary hypertension 10.0
18 tricuspid valve insufficiency 10.0
19 visceral heterotaxy 10.0 LEFTY2 NKX2-6
20 pulmonary valve disease 9.9 FLRT3 NKX2-6 SLC6A11
21 aortic valve disease 1 9.9 NKX2-6 NPPB
22 aortic valve insufficiency 9.9 NKX2-6 NPPB SLC6A1
23 endocarditis 9.9
24 constrictive pericarditis 9.9
25 pericarditis 9.9
26 transposition of the great arteries 9.9
27 noonan syndrome 1 9.7
28 pulmonic stenosis 9.7
29 myocardial infarction 9.7
30 acute myocardial infarction 9.7
31 mitral valve insufficiency 9.7
32 mitral valve stenosis 9.7
33 restrictive cardiomyopathy 9.7
34 pulmonary valve stenosis 9.7
35 pseudo-turner syndrome 9.7

Graphical network of the top 20 diseases related to Pulmonary Valve Insufficiency:



Diseases related to Pulmonary Valve Insufficiency
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Symptoms & Phenotypes for Pulmonary Valve Insufficiency

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Drugs & Therapeutics for Pulmonary Valve Insufficiency

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Drugs for Pulmonary Valve Insufficiency (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 407)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cilastatin Approved, Investigational Phase 4 82009-34-5 6435415 5280454
2
Meropenem Approved, Investigational Phase 4 119478-56-7 64778 441130
3
Imipenem Approved Phase 4 74431-23-5, 64221-86-9 104838
4
Zinc Approved, Investigational Phase 4,Phase 3,Not Applicable 7440-66-6
5 Beractant Approved Phase 4,Phase 3 108778-82-1
6 Poractant alfa Approved Phase 4 129069-19-8
7
Riluzole Approved, Investigational Phase 4,Phase 2,Phase 3 1744-22-5 5070
8
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
9
Lansoprazole Approved, Investigational Phase 4 103577-45-3 3883
10
mometasone furoate Approved, Vet_approved Phase 4,Phase 3 83919-23-7
11
Dexlansoprazole Approved, Investigational Phase 4 103577-45-3, 138530-94-6 9578005
12
Remifentanil Approved Phase 4,Phase 1,Not Applicable 132875-61-7 60815
13 tannic acid Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
14
Benzocaine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
15
Midazolam Approved, Illicit Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 59467-70-8 4192
16
Nitric Oxide Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 10102-43-9 145068
17
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable 2078-54-8 4943
18
Acetazolamide Approved, Vet_approved Phase 4,Phase 3 59-66-5 1986
19
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
20
Ropivacaine Approved Phase 4,Not Applicable 84057-95-4 175805 71273
21
Atropine Approved, Vet_approved Phase 4 51-55-8, 5908-99-6 174174
22
Diclofenac Approved, Vet_approved Phase 4,Not Applicable 15307-86-5 3033
23
Tramadol Approved, Investigational Phase 4,Not Applicable 27203-92-5 33741
24
Nalbuphine Approved Phase 4 20594-83-6 5311304 5360630
25
Orphenadrine Approved Phase 4 83-98-7 4601
26
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3,Not Applicable 437-38-7 3345
27
Adenosine Approved, Investigational Phase 4 58-61-7 60961
28
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Not Applicable 137-58-6 3676
29
Morphine Approved, Investigational Phase 4,Phase 2,Not Applicable 57-27-2 5288826
30
Naloxone Approved, Vet_approved Phase 4 465-65-6 5284596
31
Acetaminophen Approved Phase 4,Phase 3,Not Applicable 103-90-2 1983
32
Phenylephrine Approved Phase 4,Phase 2,Not Applicable 59-42-7 6041
33
Oxymetazoline Approved, Investigational Phase 4,Phase 2,Not Applicable 1491-59-4 4636
34
Ephedrine Approved Phase 4,Not Applicable 299-42-3 9294
35
Pseudoephedrine Approved Phase 4,Not Applicable 90-82-4 7028
36
Cetirizine Approved Phase 4,Phase 3 83881-51-0 2678
37
Histamine Approved, Investigational Phase 4,Phase 3 51-45-6, 75614-87-8 774
38
Levocetirizine Approved Phase 4,Phase 3 130018-77-8 1549000
39
Dexmedetomidine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 113775-47-6 68602 5311068
40
Budesonide Approved Phase 4,Phase 3 51333-22-3 63006 5281004
41
Hydromorphone Approved, Illicit Phase 4,Not Applicable 466-99-9 5284570
42
Prednisolone phosphate Approved, Vet_approved Phase 4,Phase 2,Not Applicable 302-25-0
43
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Not Applicable 83-43-2 6741
44
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Not Applicable 50-24-8 5755
45
Methylprednisolone hemisuccinate Approved Phase 4,Phase 2,Not Applicable 2921-57-5
46
Rocuronium Approved Phase 4,Not Applicable 119302-91-9, 143558-00-3 441290
47
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
48
Atracurium Approved, Experimental, Investigational Phase 4 64228-79-1 47319
49
Cisatracurium Approved Phase 4 96946-41-7
50
Sofosbuvir Approved Phase 4 1190307-88-0 45375808

Interventional clinical trials:

(show top 50) (show all 1154)
# Name Status NCT ID Phase Drugs
1 Physiological Response to Heliox21 and Air O2 Unknown status NCT01498432 Phase 4 Heliox21;Air O2
2 Immunonutrition and Thoracoabdominal Aorta Aneurysm Repair Unknown status NCT00339053 Phase 4 Immunonutrition ( Impact)
3 Comparison of Nasal CPAP and Nasal SIMV in Transient Tachypnea of Newborn Unknown status NCT01499238 Phase 4
4 Comparative Study of Non-Invasive Mask Ventilation vs Cuirass Ventilation in Patients With Acute Respiratory Failure. Unknown status NCT00331656 Phase 4
5 Short Versus Extended Antibiotic Treatment With a Carbapenem for High-risk Febrile Neutropenia in Hematology Patients With FUO Unknown status NCT02149329 Phase 4 Discontinuation of imipenem-cilastatin or meropenem
6 Neurally Adjusted Ventilatory Assist (NAVA) vs. Pressure Support in Pediatric Acute Respiratory Failure Unknown status NCT01873521 Phase 4
7 FRC Guided Therapy in Acute Respiratory Failure Unknown status NCT01280019 Phase 4
8 Acupuncture for Sedation in the Intensive Care Unit (ICU) Unknown status NCT01362270 Phase 4
9 A Trial Comparing SGC and Conventional Empiric Treatment for Glucose Control in Critically Ill Patients With Mechanical Ventilation in ICU Unknown status NCT02491346 Phase 4
10 Comparison of Pressure Support and Pressure Control Ventilation in Chronic Respiratory Failure Unknown status NCT00994552 Phase 4
11 Inspiratory Muscle Training in Hypercapnic COPD Unknown status NCT00291460 Phase 4
12 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations Unknown status NCT01941524 Phase 4 Poractant alfa instillation;Beractant instillation
13 Non-Invasive Ventilation in Amyotrophic Lateral Sclerosis Unknown status NCT00560287 Phase 4
14 The Effectiveness of Nasal Corticosteroids Versus Placebo in Nasal Obstruction in Patients With Nasal Septal Deviation Unknown status NCT02877485 Phase 4 Triamcinolone Acetonide;Ayr saline nasal mist
15 The Relationship Between Gastroesophageal Reflux and Pediatric Rhinitis: Significance of Pale/Blue Colored Turbinate Unknown status NCT02278081 Phase 4 lansoprazole;placebo
16 Acetazolamide for Respiratory Failure in Combination With Metabolic Alkalosis Completed NCT00222534 Phase 4 Acetazolamide;Placebo
17 Effect of Neuromuscular Blockade and Reversal on Breathing Completed NCT02845375 Phase 4 Sugammadex;Neostigmine;Placebo
18 Effect of Non-invasive Ventilation (NIV) on Cerebral Oxygenation Completed NCT02454582 Phase 4
19 B-type Natriuretic Peptide (BNP)-Guided Diagnostic Strategy in Intensive Care Unit (ICU) Patients With Respiratory Failure Completed NCT00130559 Phase 4
20 Diaphragmatic Reinnervation of Tetraplegic Patients With Respiratory Insufficiency Completed NCT01350297 Phase 4
21 Effects of Remifentanil on Respiratory Function in Mechanically Ventilated Patients Completed NCT00665119 Phase 4 remifentanil;placebo
22 Supplemental Oxygen and Complications After Abdominal Surgery (The PROXI-trial) Completed NCT00364741 Phase 4 Oxygen
23 Ambulatory Adaptation to Non-Invasive Mechanical Ventilation Completed NCT00698958 Phase 4
24 Comparison of Effectiveness of Nasal CPAP and Nasal IMV in Early Rescue Surfactant Treatment in Preterm Infants Completed NCT01741129 Phase 4
25 Effect of Interscalene Block on Ventilatory Function Completed NCT01740453 Phase 4 ropivacaine 2 mg/ml
26 Closed Loop Ventilation Strategy in Intensive Care Unit (ICU) Patients Completed NCT01472302 Phase 4
27 Comparison of the Efficacy for Stress Ulcer Prophylaxis Between the Patients Received Lansoprazole OD and Control Group Weaning From Mechanical Ventilator in Respiratory Care Center: a Randomized Control Trial Completed NCT00708149 Phase 4 lansoprazole OD;placebo
28 Non-invasive Ventilation in Terminally Ill Cancer Patients Completed NCT00533143 Phase 4
29 Prevention of Pressure Ulcers in Patients Under Non-Invasive Mechanical Ventilation Completed NCT02526862 Phase 4
30 Short Term Physiological Effects of Nasal High Flow Oxygen on Respiratory Mechanics Completed NCT02363920 Phase 4
31 Checklists and Upright Positioning in Endotracheal Intubation of Critically Ill Patients (Check-UP) Trial Completed NCT02497729 Phase 4
32 Diclofenac Premedication, as the Effect of Preemptive Analgesia After Post-thoracotomy Chest and Shoulder Pain Completed NCT02445599 Phase 4 Diclofenac;Midazolam;Atropine;bucain + fentanyl;Nalbuphine;Diclofenac;Metamizole-sodium;Tramadol
33 Patients-ventilator Interaction During Sleep: Effect of Humidification System Completed NCT01038791 Phase 4
34 Non-Positive Pressure Ventilation in Hypoxemic Patients Completed NCT00925860 Phase 4
35 Clinical Trial Assessing Two Protocols to Withdraw Non-invasive Ventilation in Hypercapnic Respiratory Failure Completed NCT00775710 Phase 4
36 Inhaled Nitric Oxide by Oxygen Hood in Neonates Completed NCT00732537 Phase 4 inhaled Nitric Oxide;Oxygen (>90% by hood) - standard therapy
37 Effect of Intraperitoneal and Intravenous Lignocaine on Pain Relief Following Laparoscopic Cholecystectomy Completed NCT01717222 Phase 4 Intraperitoneal Lignocaine;Intravenous Lignocaine
38 Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients Completed NCT01204281 Phase 4
39 Preventing Cardiovascular collaPse With Administration of Fluid Resuscitation Before Endotracheal Intubation Completed NCT03026777 Phase 4 intravenous crystalloid fluid, 500 mL
40 The Use of Low Dose Prophylactic Naloxone Infusion to Prevent Respiratory Depression With Intrathecal Morphine. Completed NCT02885948 Phase 4 Naloxone;Placebo
41 Chronic Obstructive Pulmonary Disease and Weaning From Mechanical Ventilation in Difficult to Wean Patients Completed NCT00355732 Phase 4
42 Helmet Ventilation in Acute Hypercapnic Respiratory Failure Completed NCT01645358 Phase 4
43 Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension Completed NCT01642407 Phase 4 Sildenafil
44 Non Invasive Mechanical Ventilation Versus Respiratory Rehabilitation in Hypercapnic COPD Completed NCT01377818 Phase 4
45 Treatment of High Altitude Polycythemia by Acetazolamide Completed NCT00424970 Phase 4 acetazolamide
46 Acetaminophen's Efficacy For Post-operative Pain Completed NCT01721486 Phase 4 IV acetaminophen;PO acetaminophen
47 Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction Completed NCT01847131 Phase 4 oxymetazoline;Placebo nasal spray
48 Effects of Slow Breathing on Blood Pressure and Autonomic Function Completed NCT01390727 Phase 4
49 The Effect of Packing in Post Operative Management of FESS Completed NCT00793117 Phase 4
50 Levocetirizine in the Treatment of Nasal Obstruction Due to Perennial Allergic Rhinitis Completed NCT00439712 Phase 4 Levocetirizine;Placebo

Search NIH Clinical Center for Pulmonary Valve Insufficiency

Cochrane evidence based reviews: pulmonary valve insufficiency

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Genetic Tests for Pulmonary Valve Insufficiency

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Anatomical Context for Pulmonary Valve Insufficiency

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MalaCards organs/tissues related to Pulmonary Valve Insufficiency:

41
Heart, Testes, Lung
Sources

Publications for Pulmonary Valve Insufficiency

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Articles related to Pulmonary Valve Insufficiency:

(show top 50) (show all 184)
# Title Authors Year
1
Pulmonary valve insufficiency 12 years after high-velocity blunt chest trauma. ( 30351411 )
2018
2
Ramipril and left ventricular diastolic function in stable patients with pulmonary regurgitation after repair of tetralogy of Fallot. ( 30153993 )
2018
3
Altered biventricular hemodynamic forces in patients with repaired Tetralogy of Fallot and right ventricular volume overload due to pulmonary regurgitation. ( 30265559 )
2018
4
The change of QRS duration after pulmonary valve replacement in patients with repaired tetralogy of Fallot and pulmonary regurgitation. ( 30360038 )
2018
5
Altered biventricular hemodynamic forces in patients with repaired tetralogy of Fallot and right ventricular volume overload because of pulmonary regurgitation. ( 30507252 )
2018
6
Flow Energy Loss as a Predictive Parameter for Right Ventricular Deterioration Caused by Pulmonary Regurgitation After Tetralogy of Fallot Repair. ( 29453683 )
2018
7
Computed tomography for evaluating right ventricle and pulmonary artery in pediatric tetralogy of Fallot: correlation with post-operative pulmonary regurgitation. ( 29760475 )
2018
8
Additional mechanism for left ventricular dysfunction: chronic pulmonary regurgitation decreases left ventricular preload in patients with tetralogy of Fallot. ( 29019299 )
2018
9
Fatal heart failure caused by severe pulmonary regurgitation, tricuspid regurgitation and late-onset mitral stenosis in an adult patient with Noonan syndrome: a case report. ( 30012103 )
2018
10
Quantification of pulmonary regurgitation and prediction of pulmonary valve replacement by echocardiography in patients with congenital heart defects in comparison to cardiac magnetic resonance imaging. ( 29119274 )
2018
11
Changes in Adrenoceptor and GRK Expression in Patients With Chronic Pulmonary Regurgitation. ( 30104167 )
2018
12
A self-expanding percutaneous valve for patients with pulmonary regurgitation and an enlarged native right ventricular outflow tract: one-year results. ( 30398963 )
2018
13
Causes and hemodynamic findings in chronic severe pulmonary regurgitation. ( 26104675 )
2018
14
Streptobacillus moniliformis Endocarditis: An Unusual Case of Pulmonary Valve Erosion Resulting in Free Pulmonary Regurgitation and Aneurysm. ( 27154799 )
2018
15
Valve-sparing repair to alleviate pulmonary regurgitation may lead to as much right ventricular dilatation as a transannular patch: A catch-22? ( 29110951 )
2018
16
Pulmonary valve cusp augmentation for pulmonary regurgitation after percutaneous balloon pulmonary valvuloplasty of valvular pulmonary stenosis. ( 29307316 )
2018
17
Branch Pulmonary Artery Valve Implantation Reduces Pulmonary Regurgitation and Improves Right Ventricular Size/Function in Patients With Large Right Ventricular Outflow Tracts. ( 29566799 )
2018
18
Right ventricular energetics and power in pulmonary regurgitation vs. stenosis using four dimensional phase contrast magnetic resonance. ( 29657080 )
2018
19
Progressive right ventricular enlargement due to pulmonary regurgitation: Clinical characteristics of a "low-risk" group. ( 29793063 )
2018
20
Trileaflet pulmonary valve reconstruction for pulmonary regurgitation in childhood. ( 29931310 )
2018
21
Pulmonary Regurgitation- Is the Future Percutaneous or Surgical? ( 30042933 )
2018
22
Longitudinal Validation of the Diastolic to Systolic Time-Velocity Integral Ratio as a Doppler-Derived Measure of Pulmonary Regurgitation in Patients with Repaired Tetralogy of Fallot. ( 27837302 )
2017
23
NT-proBNP as Marker of Ventricular Dilatation and Pulmonary Regurgitation After Surgical Correction of Tetralogy of Fallot: A MRI Validation Study. ( 27872995 )
2017
24
Cardiac magnetic resonance indices reflecting pulmonary regurgitation burden after tetralogy of Fallot repair. ( 28622796 )
2017
25
Pixel-wise derivation of pulmonary regurgitation index could influence clinical decision: A phase-contrast MR imaging study on patients with repaired tetralogy of Fallot. ( 28668430 )
2017
26
Patient outcomes after transcatheter and surgical pulmonary valve replacement for pulmonary regurgitation in patients with repaired tetralogy of Fallot: A quasi-meta-analysis. ( 28756698 )
2017
27
A new method to estimate pulmonary vascular resistance using diastolic pulmonary artery-right ventricular pressure gradients derived from continuous-wave Doppler velocity measurements of pulmonary regurgitation. ( 27576320 )
2017
28
Is long-standing pulmonary regurgitation that deleterious? Some lessons from the past. ( 27664005 )
2017
29
Impact of Elevated End-Diastolic Pulmonary Regurgitation Gradient on Worse Clinical Outcomes in Hospitalized Patients With Heart Failure. ( 27939381 )
2017
30
Five-year results from a prospective multicentre study of percutaneous pulmonary valve implantation demonstrate sustained removal of significant pulmonary regurgitation, improved right ventricular outflow tract obstruction and improved quality of life. ( 28216473 )
2017
31
Isolated pulmonary regurgitation causes decreased right ventricular longitudinal function and compensatory increased septal pumping in a porcine model. ( 28580611 )
2017
32
Quantification of Pulmonary Regurgitation by Vector Flow Mapping in Congenital Heart Patients after Repair of Right Ventricular Outflow Obstruction: A Preliminary Study. ( 28803685 )
2017
33
Pulmonary Valve Repair for Patients With Acquired Pulmonary Valve Insufficiency. ( 27083251 )
2016
34
Differential Impact of Pulmonary Regurgitation on Patients With Surgically Repaired Pulmonary Stenosis Versus Tetralogy of Fallot. ( 26651611 )
2016
35
Pulmonary Valve Replacement With Fresh Decellularized Pulmonary Allograft for Pulmonary Regurgitation After Tetralogy of Fallot Repair　- First Case Report in Japan. ( 26924076 )
2016
36
NT-proBNP Indicates Left Ventricular Impairment and Adverse Clinical Outcome in Patients With Tetralogy of Fallot and Pulmonary Regurgitation. ( 26927857 )
2016
37
Transcatheter implantation of SAPIEN 3 valve in native right ventricular outflow tract for severe pulmonary regurgitation following tetralogy of fallot repair. ( 26945801 )
2016
38
Vicious circle between progressive right ventricular dilatation and pulmonary regurgitation in patients after tetralogy of Fallot repair? Right heart enlargement promotes flow reversal in the left pulmonary artery. ( 27268132 )
2016
39
Erratum: Pulmonary stenosis and pulmonary regurgitation: both ends of the spectrum in residual hemodynamic impairment after tetralogy of Fallot repair. ( 27721844 )
2016
40
Usefulness of maximal oxygen pulse in timing of pulmonary valve replacement in patients with isolated pulmonary regurgitation. ( 26692200 )
2016
41
Sequential Right and Left Ventricular Assessment in Posttetralogy of Fallot Patients with Significant Pulmonary Regurgitation. ( 27225732 )
2016
42
Successful Transcatheter Handmade-Valved Graft Stent for Branch Pulmonary Regurgitation: Novel Approach in a Special Event. ( 27847076 )
2016
43
Should Tricuspid Annuloplasty be Performed With Pulmonary Valve Replacement for Pulmonary Regurgitation in Repaired Tetralogy of Fallot? ( 26686442 )
2015
44
What can pulmonary regurgitation indices reflect in patients after tetralogy of Fallot repair? ( 25179477 )
2015
45
The Effects of Pulmonary Valve Replacement for Severe Pulmonary Regurgitation on Exercise Capacity and Cardiac Function. ( 25753686 )
2015
46
Percutaneous pulmonary valve implantation for free pulmonary regurgitation following conduit-free surgery of the right ventricular outflow tract. ( 25818755 )
2015
47
Effects of milrinone and epinephrine or dopamine on biventricular function and hemodynamics in right heart failure after pulmonary regurgitation. ( 26092988 )
2015
48
Variability of Pulmonary Regurgitation in Proportion to Pulmonary Vascular Resistance in a Porcine Model of Total Resection of the Pulmonary Valve: Implications for Early- and Long-Term Postoperative Management of Right Ventricular Outflow Tract Reconstruction With Resulting Pulmonary Valve Incompetence. ( 26467862 )
2015
49
Tricuspid Regurgitation Secondary to Severe Pulmonary Regurgitation: When to Operate on Which Valves? ( 26652560 )
2015
50
Quantitative assessment of right ventricular function and pulmonary regurgitation in surgically repaired tetralogy of Fallot using 256-slice CT: comparison with 3-Tesla MRI. ( 25113649 )
2014
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Variations for Pulmonary Valve Insufficiency

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Expression for Pulmonary Valve Insufficiency

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Search GEO for disease gene expression data for Pulmonary Valve Insufficiency.
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Pathways for Pulmonary Valve Insufficiency

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Pathways related to Pulmonary Valve Insufficiency according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Benzodiazepine Pathway, Pharmacodynamics 61
Show member pathways
 9.88 SLC6A1 SLC6A11
Sources

GO Terms for Pulmonary Valve Insufficiency

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Cellular components related to Pulmonary Valve Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 GABA-ergic synapse GO:0098982 9.16 SLC6A1 SLC6A11
2 integral component of presynaptic membrane GO:0099056 8.96 SLC6A1 SLC6A11
3 integral component of postsynaptic membrane GO:0099055 8.8 FLRT3 SLC6A1 SLC6A11

Biological processes related to Pulmonary Valve Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neurotransmitter transport GO:0006836 8.96 SLC6A1 SLC6A11
2 gamma-aminobutyric acid transport GO:0015812 8.62 SLC6A1 SLC6A11

Molecular functions related to Pulmonary Valve Insufficiency according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 symporter activity GO:0015293 9.16 SLC6A1 SLC6A11
2 neurotransmitter binding GO:0042165 8.96 SLC6A1 SLC6A11
3 gamma-aminobutyric acid:sodium symporter activity GO:0005332 8.62 SLC6A1 SLC6A11
Sources

Sources for Pulmonary Valve Insufficiency

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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