Drugs for Pulmonary Venoocclusive Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):
(show all 21)
# |
|
Name |
Status |
Phase |
Clinical Trials |
Cas Number |
PubChem Id |
1 |
|
Bevacizumab |
Approved, Investigational |
Phase 1, Phase 2 |
|
216974-75-3 |
|
Synonyms:
216974-75-3
antiVEGF
anti-VEGF monoclonal antibody
Avastin
Avastin (TN)
bevacizumab
|
Bevacizumab
Bevacizumab (genetical recombination)
Bevacizumab (genetical recombination) (JAN)
bevacizumab-awwb
D06409
R-435
|
|
2 |
|
Orange |
Approved |
Phase 1, Phase 2 |
|
|
|
3 |
|
Protein Kinase Inhibitors |
|
Phase 1, Phase 2 |
|
|
|
4 |
|
Angiogenesis Modulating Agents |
|
Phase 1, Phase 2 |
|
|
|
5 |
|
Anti-Bacterial Agents |
|
Phase 1, Phase 2 |
|
|
|
6 |
|
Imatinib Mesylate |
|
Phase 1, Phase 2 |
|
220127-57-1 |
123596
|
7 |
|
Angiogenesis Inhibitors |
|
Phase 1, Phase 2 |
|
|
|
8 |
|
Cocaine |
Approved, Illicit |
|
|
50-36-2 |
5760
446220
|
Synonyms:
(−)-cocaine
(-)-Cocaine
(-)-Cocaine base
(1R,2R,3S,5S)-2-(methoxycarbonyl)tropan-3-yl benzoate
(1R,2R,3S,5S)-2-Methoxycarbonyltropan-3-yl benzoate
(R)-Cocaine
[1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate, methyl ester
[1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester
[1R-(exo,exo)]-3-(Benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid, methyl ester
1-Cocaine
1i7z
1q72
2beta-Carbomethoxy-3beta-benzoxytropane
2-beta-Carbomethoxy-3-beta-benzoxytropane
2-beta-Tropanecarboxylic acid, 3-beta-hydroxy-, methyl ester, benzoate (ester)
2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylate benzoate (ester)
2-Methyl-3beta-hydroxy-1alphah,5alphah-tropane-2beta-carboxylic acid benzoic acid (ester)
2-Methyl-3b-hydroxy-1alphah,5alphah-tropane-2b-carboxylate benzoate (ester)
2-Methyl-3b-hydroxy-1alphah,5alphah-tropane-2b-carboxylic acid benzoic acid (ester)
2-Methyl-3β-hydroxy-1alphah,5alphah-tropane-2β-carboxylate benzoate (ester)
2-Methyl-3β-hydroxy-1alphah,5alphah-tropane-2β-carboxylic acid benzoic acid (ester)
2-methyl-3β-hydroxy-1αH,5αH-tropane-2β-carboxylate benzoate (ester)
3beta-Hydroxy-2beta-tropanecarboxylic acid methyl ester benzoate (ester)
3-Tropanylbenzoate-2-carboxylic acid methyl ester
50-36-2
53-21-4 (hydrochloride)
610089_ALDRICH
610089_FLUKA
AC-16037
AC1L1EK2
AC1L1L2T
AC1L3U2D
AC1L9JBL
AC-20208
Allococaine
Allopseudococaine
Badrock
Bazooka
b-Cocain
Benzoylethylecgonine
Benzoylmethylecgonine
Bernice
Bernice [Street Name]
Bernies
beta-Cocain
Beta-Cocain
Blast
Blizzard
Blow
Blow [Street Name]
Bouncing Powder
Bump
Burese
C" Carrie
C01416
C8912_SIGMA
Cabello
Candy
Carrie
Caviar
Cecil
Cecil [Street Name]
Charlie
CHEBI:27958
Chicken Scratch
Cholly
CID11779748
CID2826
CID446220
CID5760
COC
Coca
Cocain
Cocaina
cocaine
Cocaine
Cocaine (TN)
Cocaine (USP)
Cocaine [BAN]
Cocaine free base
Cocaine Free Base
Cocaine HCL
Cocaine hydrochloride
Cocaine solution
Cocaine-M
cocainum
Cocainum
Cocktail
Coke
Cola
Corine
CPD-9776
Crack
Crack cocaine
D00110
Dama blanca
Dama Blanca
DB00907
DEA No. 9041
Delcaine
Depsococaine
Dextrocaine
DivK1c_000975
|
d-Pseudococaine
D-pseudococaine
Dust
Ecgonine methyl ester benzoate
Ecgonine methyl ester benzoate solution
Ecgonine, methyl ester, benzoate (ester)
EINECS 200-032-7
Eritroxilina
Erytroxylin
Flake
Flake [Street Name]
Flex
Florida Snow
Foo Foo
Freeze
Girl
Girl [Street Name]
Gold dust
Gold Dust
Gold dust [Street Name]
Goofball
Green gold
Green Gold
G-Rock
Happy dust
Happy Dust
Happy dust [Street Name]
Happy powder
Happy Powder
Happy trails
Happy Trails
HCL, Cocaine
Heaven
Hell
HSDB 6469
Hydrochloride, cocaine
IDI1_000975
Isocaine
Isococain
Isococaine
Jam
KBio1_000975
Kibbles n' Bits
Kibbles N' Bits
Kokain
Kokan
Kokayeen
L000836
Lady
Lady [Street Name]
l-Cocain
L-Cocain
L-Cocaine
Leaf
LS-157759
methyl (1S,4R,5R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
methyl (3S,4R)-3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
Methyl [1R-(exo,exo)]-3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylic acid
Methyl 3-(benzoyloxy)-8-methyl-8-azabicyclo[3.2.1]octane-2-carboxylate
methyl 3-benzoyloxy-8-methyl-8-azabicyclo[3.2.1]octane-4-carboxylate
Methyl 3beta-hydroxy-1alphaH,5alphaH-tropane-2beta-carboxylate benzoate (ester)
Methyl benzoylecgonine
Methyl Benzoylecgonine
MLS002320697
MolPort-002-535-520
MolPort-003-937-722
Moonrocks
NCGC00159467-02
nchembio.284-comp4
Neurocaine
NINDS_000975
Nose candy
Pimp's drug
Pimp's Drug
Prime Time
Pseudoallococaine
Pseudococaine
Rock
Rock [Street Name]
Sleighride
SMR001338843
Snort
Snow
Snow (birds)
Star dust
Star Dust
Star-spangled powder
Star-Spangled Powder
STOCK1N-68258
Sugar
Sweet Stuff
Toke
Toot
Toot [Street Name]
Trails
UNII-I5Y540LHVR
White girl or lady
Yeyo
Zip
β-cocain
|
|
9 |
|
Ambrisentan |
Approved, Investigational |
|
|
177036-94-1 |
6918493
|
Synonyms:
(+-)-(2S)-2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-methoxy-3,3-diphenylpropanoic acid
(2S)-2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy- 3,3-diphenylpropanoic acid
177036-94-1
2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenylpropanoic acid
2-(4,6-dimethylpyrimidin-2-yl)oxy-3-methoxy-3,3-diphenyl-propanoic acid
2-[(4,6-dimethylpyrimidin-2-yl)oxy]-3-methoxy-3,3-diphenylpropanoic acid
AC1L53VT
Ambrisentan
Ambrisentan [INN]
Benzenepropanoic acid, .alpha.-[(4,6-dimethyl-2-pyrimidinyl)oxy]-.beta.-methoxy-.beta.-phe
BSF 208075
BSF208075
BSF-208075
C467894
CHEBI:205299
CHEMBL302753
|
CID197712
Gilead brand of ambrisentan
I06-2077
Letairis
LS-186563
LS-187364
LU 208075
LU208075
LU-208075
MLS001195278
MolPort-002-945-567
NCGC00160662-01
SMR000502713
ST51051295
STK097095
UNII-HW6NV07QEC
|
|
10 |
|
Bosentan |
Approved, Investigational |
|
|
147536-97-8 |
104865
|
Synonyms:
147536-97-8
174227-18-0
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulfornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl) benzenesulphornamide
4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-(2,2'-bipyrimidin)-4-yl)benzenesulfornamide
4-t-butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
4-t-Butyl-N-(6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl)benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2,2'-bipyrimidin-4-yl]benzenesulfonamide
4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)-2-pyrimidin-2-ylpyrimidin-4-yl]benzenesulfonamide
-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl]benzenesulfonamide
AC-148
AC1L2XN2
Actelion
bosentan
Bosentan
bosentán
Bosentan (INN)
Bosentan [USAN:INN:BAN]
bosentan anhydrous
Bosentan anhydrous
Bosentan hydrate
Bosentan monohydrate
bosentanum
Bosentanum
C27H29N5O6S
CHEBI:51450
|
CHEMBL957
CID104865
D07538
DB00559
EN002863
HMS2090N14
I06-1873
KS-5062
L001086
LS-31532
MolPort-003-845-300
NCGC00167440-01
PDSP1_001731
PDSP2_001714
p-tert-Butyl-N-(6-(2-hydroxyethoxy)-5-(o-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
P-Tert-butyl-N-(6-(2-hydroxyethoxy)-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulfonamide
P-Tert-butyl-N-(6-(2-hydroxyethoxy)-5-(O-methoxyphenoxy)-2-(2-pyrimidinyl)-4-pyrimidinyl)benzenesulphonamide
p-tert-Butyl-N-[6-(2-hydroxyethoxy)
Ro 47-0203
Ro 47-0203/039
Ro-47-0203
Ro-47-0203/029
Ro-47-0203/039
TL8001039
Tracleer
UNII-XUL93R30K2
|
|
11 |
|
Methamphetamine |
Approved, Illicit |
|
|
537-46-2 |
10836
|
Synonyms:
(+ )-methylamphetamine
(+ )-Methylamphetamine
(+)-(s)-deoxyephedrine
(+)-(S)-Deoxyephedrine
(+)-(S)-N-a-Dimethylphenethylamine
(+)-(s)-n-alpha-dimethylphenethylamine
(+)-(S)-N-alpha-Dimethylphenethylamine
(+)-(S)-N-α-dimethylphenethylamine
(+)-2-(N-methylamino)-1-Phenylpropane
(+)-2-(N-Methylamino)-1-phenylpropane
(+)-methamphetamine
(+)-Methamphetamine
(+)-methylamphetamine
(+)-Methylamphetamine
(+)-n,alpha-dimethyl-beta-phenylethylamine
(+)-N,alpha-Dimethyl-beta-phenylethylamine
(+)-n,alpha-dimethylphenethylamine
(+)-N,alpha-Dimethylphenethylamine
(+)-n-methylamphetamine
(+)-N-Methylamphetamine
(2S)-N-methyl-1-phenylpropan-2-amine
(2S)-N-Methyl-1-phenylpropan-2-amine
(AlphaS)-N,a-dimethylbenzeneethanamine
(alphaS)-N,alpha-dimethylbenzeneethanamine
(AlphaS)-N,alpha-dimethylbenzeneethanamine
(AlphaS)-N,α-dimethylbenzeneethanamine
(s)-(+)-deoxyephedrine
(S)-(+)-Deoxyephedrine
(s)-(+)-methamphetamine
(S)-(+)-Methamphetamine
(s)-(+)-n,alpha,dimethylphenethylamine
(S)-(+)-N,alpha,dimethylphenethylamine
(S)-(+)-N,alpha,Dimethylphenethylamine
(s)-methamphetamine
(S)-Methamphetamine
(s)-methylamphetamine
(S)-Methylamphetamine
(S)-N,a-Dimethylbenzeneethanamine
(s)-n,alpha-dimethylbenzeneethanamine
(S)-N,alpha-Dimethylbenzeneethanamine
(s)-n,alpha-dimethylbenzeneethanoamine
(S)-N,alpha-Dimethylbenzeneethanoamine
(S)-N,α-dimethylbenzeneethanamine
(αS)-N,α-dimethylbenzeneethanamine
139-47-9
14611-50-8
1690-86-4
1-Phenyl-2-methylamino-propan
1-Phenyl-2-methylamino-propan [German]
1-Phenyl-2-methylaminopropane
2S-(+)-Methamphetamine
45952-89-4
537-46-2
Abbott brand OF methamphetamine hydrochloride
AC1L1W1Z
AC1Q4SVR
B40
Benzeneethanamine, N,alpha-dimethyl-, (alphaS)- (9CI)
Benzeneethanamine, N,alpha-dimethyl-, (S)- (9CI)
C07164
C10H15N
CHEBI:6809
CHEMBL1201201
CID10836
Crank
Crank [Street Name]
Crystal Meth
Crystal Meth [Street Name]
d-(S)-Methamphetamine
D-(s)-methamphetamine
D-(S)-Methamphetamine
D08187
D-1-Phenyl-2-methylaminopropan
d-1-Phenyl-2-methylaminopropan [German]
d-1-phenyl-2-methylaminopropane
D-1-Phenyl-2-methylaminopropane
DB01577
d-deoxyephedrine
d-Deoxyephedrine
D-deoxyephedrine
D-Deoxyephedrine
d-desoxyephedrine
d-Desoxyephedrine
D-desoxyephedrine
D-Desoxyephedrine
DEA No. 1105
Deoxyephedrine
desohyephedrine
Desoxyephedrine
Desoxyephedrine hydrochloride
|
Desoxyn
Desyphed
Desyphed hydrochloride
Dextromethamphetamine
d-Methamphetamine
D-methamphetamine
D-Methamphetamine
d-Methylamphetamine
D-methylamphetamine
D-Methylamphetamine
d-N,.alpha.-Dimethylphenethylamine
D-n,alpha-dimethylphenethylamine
D-N,alpha-dimethylphenethylamine
D-N,alpha-Dimethylphenethylamine
d-N-methylamphetamine
d-N-Methylamphetamine
D-n-methylamphetamine
D-N-Methylamphetamine
d-phenylisopropylmethylamine
d-Phenylisopropylmethylamine
D-phenylisopropylmethylamine
D-Phenylisopropylmethylamine
EINECS 208-668-7
HSDB 3359
Hydrochloride, methamphetamine
Ice
ICE [Street Name]
Langly brand OF methamphetamine hydrochloride
L-methamphetamine
L-Methamphetamine
LS-103331
Madrine
Metamfetamina
Metamfetamina [inn-spanish]
Metamfetamina [INN-Spanish]
Metamfetamine
Métamfétamine
Metamfetamine (INN)
Metamfetamine [INN]
Metamfetamine-m
Metamfetaminum
Metamfetaminum [inn-latin]
Metamfetaminum [INN-Latin]
Metamfetaminum [Latin]
Metamphetamine
Metanfetamina
Metanfetamina [inn-spanish]
Metanfetamina [INN-Spanish]
Metanfetamina [Spanish]
Meth
Meth (Street Name)
Methamphetamine
METHAMPHETAMINE
Methamphetamine hydrochloride
Methamphetamine, its salts, isomers, and salts of its isomers
Methamphetaminum
Methamphetaminum [inn-latin]
Methamphetaminum [INN-Latin]
Methamphetaminum [JP]
Methyl-.beta.-phenylisopropylamine
Methylamphetamine
Methyl-beta-phenylisopropylamine
Methyl-b-phenylisopropylamine
methyl-β-phenylisopropylamine
Methyl-β-phenylisopropylamine
MolPort-001-794-405
N Methylamphetamine
N-Methyl-1-phenyl-2-propanamine
N-methylamphetamine
N-Methylamphetamine
N-Methyl-beta-phenylisopropylamin
N-methyl-beta-phenylisopropylamin [german]
N-Methyl-beta-phenylisopropylamin [German]
N-methyl-beta-phenylisopropylamine
N-Methyl-beta-phenylisopropylamine
Norodin
NSC 25115
NSC25115
PDSP1_001404
PDSP1_001405
PDSP2_001388
PDSP2_001389
Phenethylamine, N,alpha-dimethyl-, (S)-(+)- (8CI)
S-(+)-methamphetamine
S-(+)-Methamphetamine
Speed
Speed [Street Name]
Stimulex
UNII-44RAL3456C
WLN: 1MY1&1R -D
|
|
12 |
|
Citric Acid |
Approved, Nutraceutical, Vet_approved |
|
|
77-92-9 |
311
|
Synonyms:
2-hydroxy-1,2,3-propanetricarboxyic acid
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylate
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-carboxy-3-hydroxypentane-1,5-dioic acid
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Acid monohydrate, citric
Acidum citricum
Aciletten
Anhydrous citrate
Anhydrous citric acid
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid
Chemfill
Citraclean
Citrate
|
Citretten
Citric acid monoglyceride
Citric acid monohydrate
Citric acid, anhydrous
Citric Acid, Anhydrous
Citric acid,anhydrous
Citro
Citronensaeure
Citronensäure
e 330
e330
H3Cit
Hydrocerol a
Kyselina citronova
Monohydrate, citric acid
Suby g
Uralyt u
uro-Trainer
|
|
13 |
|
glutamine |
|
Not Applicable |
|
|
|
14 |
|
Tryptophan |
|
|
|
|
|
15 |
|
Antihypertensive Agents |
|
|
|
|
|
16 |
|
Endothelin Receptor Antagonists |
|
|
|
|
|
17 |
|
Sildenafil Citrate |
|
|
|
171599-83-0 |
|
18 |
|
Phosphodiesterase Inhibitors |
|
|
|
|
|
19 |
|
Vasodilator Agents |
|
|
|
|
|
20 |
|
Citrate |
|
|
|
|
|
21 |
|
Phosphodiesterase 5 Inhibitors |
|
|
|
|
|
Interventional clinical trials:
# |
Name |
Status |
NCT ID |
Phase |
Drugs |
1 |
Pilot Study Using Avastin and Gleevec to Treat the Progression of Intraluminal Pulmonary Vein Stenosis |
Completed |
NCT00891527
|
Phase 1, Phase 2 |
Bevacizumab (Avastin) and Imatinib Mesylate (Gleevec) |
2 |
Effects on Glutamine on the Outcome of Allogeneic Bone Marrow Transplant Recipients |
Unknown status |
NCT00563498
|
Not Applicable |
Glutamine |
3 |
Pharmacogenomics in Pulmonary Arterial Hypertension |
Unknown status |
NCT00593905
|
|
Sitaxsentan;Bosentan, Ambrisentan |
4 |
Special Investigation For Long-Term Use Of Sildenafil (Regulatory Post Marketing Commitment Plan) |
Completed |
NCT00666198
|
|
SILDENAFIL |
5 |
Registration Study for Rare Type of Pulmonary Hypertension |
Recruiting |
NCT03169010
|
|
|
|