MCID: PRP034
MIFTS: 43

Purpura Fulminans

Categories: Blood diseases, Rare diseases, Skin diseases

Aliases & Classifications for Purpura Fulminans

MalaCards integrated aliases for Purpura Fulminans:

Name: Purpura Fulminans 12 54 43 15 17 71
Purpura Gangrenosa 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060538
MeSH 43 D055665
ICD10 32 D65
UMLS 71 C0085650

Summaries for Purpura Fulminans

Disease Ontology : 12 A purpura characterized blood spots, bruising and discolouration of the skin resulting from coagulation in small blood vessels within the skin and rapidly leads to skin necrosis and disseminated intravascular coagulation. It is often fatal.

MalaCards based summary : Purpura Fulminans, also known as purpura gangrenosa, is related to protein c deficiency and protein s deficiency. An important gene associated with Purpura Fulminans is PROC (Protein C, Inactivator Of Coagulation Factors Va And VIIIa), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Drotrecogin alfa activated and Anti-Infective Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, brain and liver, and related phenotypes are Decreased replication of vaccinia virus (VACV) and cardiovascular system

Wikipedia : 74 Purpura fulminans is an acute, often fatal, thrombotic disorder which manifests as blood spots, bruising... more...

Related Diseases for Purpura Fulminans

Diseases in the Purpura Fulminans family:

Acquired Purpura Fulminans

Diseases related to Purpura Fulminans via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 350, show less)
# Related Disease Score Top Affiliating Genes
1 protein c deficiency 31.3 THBD SERPINC1 PROCR PROC F5 F2
2 protein s deficiency 31.0 THBD SERPINC1 PROS1 PROC F5 F3
3 compartment syndrome 30.8 SERPINC1 F3 F2
4 waterhouse-friderichsen syndrome 30.7 SERPINC1 F3 F2
5 endocarditis 30.7 SERPINC1 F2 APOH
6 leech infestation 30.7 SERPINC1 F3
7 lemierre's syndrome 30.3 SERPINC1 F3 F2
8 vasculitis 30.3 THBD SERPINA1 APOH
9 mitral valve stenosis 30.3 SERPINC1 F3 F2
10 factor vii deficiency 30.3 SERPINC1 F3 F2
11 anuria 30.3 F3 F2
12 purpura 30.2 THBD SERPINC1 PROS1 PROCR PROC F3
13 meningococcemia 29.9 THBD SERPINC1 PROCR PROC F5
14 raynaud phenomenon 29.8 THBD APOH
15 catastrophic antiphospholipid syndrome 29.7 PROC F5 F3 APOH
16 disseminated intravascular coagulation 29.6 THBD SERPINF2 SERPINC1 PROCR F5 F3
17 hemolytic anemia 29.4 THBD F3 F2 APOH
18 typhoid fever 29.4 THBD SIGLEC5 F2
19 afibrinogenemia, congenital 29.3 SERPINF2 SERPINC1 F5 F3 F2
20 respiratory failure 29.2 THBD SERPINA1 F3 F2
21 thrombotic thrombocytopenic purpura 29.1 THBD SERPINF2 SERPINC1 F3 APOH
22 malaria 29.1 THBD SERPINC1 PROCR F3 F2 APOH
23 thrombocytopenia 29.0 THBD SERPINC1 F5 F3 F2 APOH
24 acute promyelocytic leukemia 28.9 THBD SERPINF2 SERPINC1 F3 F2
25 thrombophlebitis 28.7 SERPINF2 SERPINC1 PROS1 PROC F5 F3
26 antiphospholipid syndrome 28.6 THBD SERPINC1 PROCR F5 F3 F2
27 thrombophilia due to activated protein c resistance 28.5 THBD SERPINF2 SERPINC1 F5 F3 F2
28 thrombophilia due to thrombin defect 28.4 THBD SERPINC1 PROCR PROC F5 F3
29 vascular disease 28.4 THBD SERPINC1 F5 F3 F2 APOH
30 pulmonary embolism 27.7 THBD SERPINF2 SERPINC1 PROS1 PROC F5
31 thrombophilia 27.5 THBD SERPINF2 SERPINC1 PROS1 PROCR PROC
32 thrombosis 27.4 THBD SERPINF2 SERPINC1 PROS1 PROCR PROC
33 acquired purpura fulminans 12.6
34 thrombophilia due to protein c deficiency, autosomal recessive 11.9
35 thrombophilia due to protein s deficiency, autosomal recessive 11.9
36 chickenpox 10.8
37 toxic shock syndrome 10.8
38 exanthem 10.6
39 meningitis 10.5
40 femoral vein thrombophlebitis 10.5 PROC F2
41 neisseria meningitidis infection 10.5
42 achenbach syndrome 10.4 F3 F2
43 acute kidney failure 10.4
44 scarlet fever 10.4
45 synovial angioma 10.4 F3 F2
46 renal pelvis squamous cell carcinoma 10.4 F3 F2
47 papillary adenofibroma 10.4 F3 F2
48 emphysematous cholecystitis 10.4 F3 F2
49 femoral neuropathy 10.4 F3 F2
50 heparin-induced thrombocytopenia 10.4 SERPINC1 F3
51 hemopneumothorax 10.4 F3 F2
52 gastric hemangioma 10.4 F3 F2
53 qualitative platelet defect 10.4 F3 F2
54 ankylosing spondylitis 1 10.4 F3 F2
55 hemopericardium 10.4 F3 F2
56 epidural abscess 10.4 F3 F2
57 thoracic outlet syndrome 10.4 SERPINC1 F2
58 cholesterol embolism 10.4 SERPINC1 F2
59 abducens nerve disease 10.4 SERPINC1 F2
60 vulvar angiokeratoma 10.4 SERPINC1 F3
61 cerebral falx meningioma 10.4 F3 F2
62 intracranial hypotension 10.3 F3 F2
63 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 10.3
64 haemophilus influenzae 10.3
65 meningococcal infection 10.3
66 branch retinal artery occlusion 10.3 SERPINC1 F2
67 splenic sequestration 10.3 F3 F2
68 active peptic ulcer disease 10.3 F3 F2
69 mastoiditis 10.3 SERPINC1 F2
70 acute hemorrhagic encephalitis 10.3 F3 F2
71 platelet aggregation, spontaneous 10.3 SERPINF2 SERPINC1
72 central retinal artery occlusion 10.3 SERPINC1 F2
73 cold urticaria 10.3 SERPINF2 SERPINC1
74 analbuminemia 10.3 F3 F2
75 hantavirus pulmonary syndrome 10.3 F3 F2
76 carotid artery thrombosis 10.3 SERPINC1 F3
77 viral laryngitis 10.3 SERPINA1 PROC
78 hemarthrosis 10.3 F3 F2
79 arteritic anterior ischemic optic neuropathy 10.3 F5 F2
80 hereditary angioedema with normal c1inh 10.3 SERPINA1 PROC
81 paracetamol poisoning 10.3 F5 F2
82 adult respiratory distress syndrome 10.3
83 meningococcal meningitis 10.3
84 epidemic typhus 10.3
85 bacterial sepsis 10.3
86 lupus erythematosus 10.3
87 bacterial meningitis 10.3
88 fasciitis 10.3
89 necrotizing fasciitis 10.3
90 intracranial hypertension, idiopathic 10.2 F3 F2
91 fournier gangrene 10.2 SERPINC1 F3 F2
92 acquired hemophilia 10.2 F5 F3
93 blue toe syndrome 10.2 SERPINC1 F3 F2
94 acquired hemophilia a 10.2 F5 F3
95 lateral sinus thrombosis 10.2 SERPINC1 F3 F2
96 cavernous sinus thrombosis 10.2 SERPINC1 F3 F2
97 intracranial sinus thrombosis 10.2 SERPINC1 F3 F2
98 intracranial embolism 10.2 SERPINC1 F3 F2
99 hepatic coma 10.2 SERPINC1 F3 F2
100 coronary thrombosis 10.2 SERPINC1 F3 F2
101 sticky platelet syndrome 10.2 SERPINC1 F5
102 congenital disorder of glycosylation, type ib 10.2 SERPINC1 SERPINA1
103 cryptogenic cirrhosis 10.2 F5 F2
104 may-thurner syndrome 10.2 F5 APOH
105 moyamoya disease 1 10.2 SERPINC1 F3 F2
106 acanthamoeba keratitis 10.2 F5 APOH
107 placental insufficiency 10.2 SERPINC1 F3 F2
108 cardiac tamponade 10.2 F3 F2
109 spotted fever 10.2
110 bacterial infectious disease 10.2
111 cardiac arrest 10.2
112 indian tick typhus 10.2
113 systemic lupus erythematosus 10.2
114 kidney disease 10.2
115 measles 10.2
116 hypoglycemia 10.2
117 heart conduction disease 10.2 SERPINC1 F3 F2
118 thrombocytosis 10.2 SERPINC1 F3 F2
119 primary thrombocytopenia 10.2 F3 F2
120 intermittent claudication 10.2 SERPINC1 F2 APOH
121 tricuspid valve insufficiency 10.1 F3 F2
122 atrial heart septal defect 10.1 SERPINC1 F3 F2
123 pregnancy loss, recurrent 1 10.1 F5 APOH
124 diabetes mellitus 10.1
125 encephalopathy, familial, with neuroserpin inclusion bodies 10.1 SERPINC1 SERPINA1
126 alcohol use disorder 10.1
127 meningoencephalitis 10.1
128 limb ischemia 10.1
129 metabolic acidosis 10.1
130 erythema multiforme 10.1
131 pulmonary fibrosis and/or bone marrow failure, telomere-related, 2 10.1
132 west nile virus 10.1
133 complement component 7 deficiency 10.1
134 aplastic anemia 10.1
135 severe cutaneous adverse reaction 10.1
136 branchiootic syndrome 1 10.1
137 retinal detachment 10.1
138 alcohol dependence 10.1
139 leptospirosis 10.1
140 lactic acidosis 10.1
141 pleural empyema 10.1
142 endophthalmitis 10.1
143 pneumonia 10.1
144 septic arthritis 10.1
145 myocarditis 10.1
146 peritonitis 10.1
147 arthritis 10.1
148 stevens-johnson syndrome/toxic epidermal necrolysis 10.1
149 erythema multiforme major 10.1
150 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 10.1
151 overgrowth syndrome 10.1
152 alpha-1-antitrypsin deficiency 10.1 SERPINC1 SERPINA1 F2
153 puerperal pulmonary embolism 10.1 SERPINC1 SERPINA1 APOH
154 angiodysplasia 10.1 SIGLEC5 F3
155 mediastinitis 10.1 F5 F3 F2
156 tricuspid valve disease 10.1 F3 F2
157 vitamin k deficiency bleeding 10.1 SERPINC1 PROS1 F3 F2
158 thrombasthenia 10.1 F5 F3 F2
159 factor x deficiency 10.1 F5 F3 F2
160 von willebrand disease, type 1 10.1 SIGLEC5 F3 F2
161 splenic disease 10.0 SIGLEC5 F3 F2
162 blood protein disease 10.0 SERPINC1 PROS1 F3 F2
163 von willebrand's disease 10.0 F5 F3 F2
164 ebola hemorrhagic fever 10.0 F5 F3
165 hepatic infarction 10.0 SERPINC1 F3 F2 APOH
166 marantic endocarditis 10.0 SERPINC1 F3 F2 APOH
167 prothrombin deficiency 10.0 SERPINC1 F3 F2 APOH
168 infective endocarditis 10.0 SIGLEC5 F2 APOH
169 myopathy, lactic acidosis, and sideroblastic anemia 1 10.0 SERPINF2 COX5A
170 splenic infarction 10.0 SERPINC1 F3 F2 APOH
171 pyoderma 10.0 SIGLEC5 F3 APOH
172 pyoderma gangrenosum 10.0 SIGLEC5 F3 APOH
173 papilledema 10.0 SERPINC1 F3 F2 APOH
174 giant hemangioma 10.0 SERPINF2 SERPINC1 F3 F2
175 dic in newborn 10.0 SERPINF2 SERPINC1 F3 F2
176 alpha-2-plasmin inhibitor deficiency 10.0 SERPINF2 SERPINC1 F3 F2
177 severe pre-eclampsia 10.0 SERPINC1 F5 APOH
178 scrub typhus 10.0
179 thrombophlebitis migrans 10.0
180 hypothyroidism 10.0
181 hereditary angioedema 10.0
182 angioedema 10.0
183 pancytopenia 10.0
184 leukemia 10.0
185 neutropenia 10.0
186 dengue hemorrhagic fever 10.0
187 cryptococcosis 10.0
188 streptococcal meningitis 10.0
189 diphtheria 10.0
190 subdural empyema 10.0
191 tetanus 10.0
192 pasteurellosis 10.0
193 hydrocephalus 10.0
194 common cold 10.0
195 viral meningitis 10.0
196 osteomyelitis 10.0
197 osteonecrosis 10.0
198 angioimmunoblastic t-cell lymphoma 10.0
199 salmonellosis 10.0
200 colitis 10.0
201 pain agnosia 10.0
202 lymphoma 10.0
203 autosomal recessive disease 10.0
204 inflammatory bowel disease 10.0
205 aspiration pneumonia 10.0
206 dengue shock syndrome 10.0
207 hemophagocytic lymphohistiocytosis 10.0
208 rocky mountain spotted fever 10.0
209 israeli tick typhus 10.0
210 streptococcus pneumonia 10.0
211 deficiency anemia 10.0
212 chronic ulcer of skin 10.0
213 juvenile arthritis 10.0
214 hemorrhage, intracerebral 10.0
215 cyanosis, transient neonatal 10.0
216 thrombophilia due to protein s deficiency, autosomal dominant 10.0
217 kawasaki disease 10.0
218 anemia, x-linked, with or without neutropenia and/or platelet abnormalities 10.0
219 myeloma, multiple 10.0
220 mowat-wilson syndrome 10.0
221 galactosemia i 10.0
222 enterocolitis 10.0
223 lung cancer 10.0
224 thrombocytopenic purpura, autoimmune 10.0
225 testicular torsion 10.0
226 rheumatoid arthritis 10.0
227 otitis media 10.0
228 leukemia, chronic lymphocytic 10.0
229 autoimmune disease 10.0
230 atrial standstill 1 10.0
231 pfeiffer syndrome 10.0
232 rectum adenocarcinoma 10.0
233 autoimmune hepatitis 10.0
234 pharyngitis 10.0
235 west nile encephalitis 10.0
236 west nile fever 10.0
237 hemoglobinopathy 10.0
238 churg-strauss syndrome 10.0
239 ischemia 10.0
240 bone inflammation disease 10.0
241 cellulitis 10.0
242 mixed connective tissue disease 10.0
243 shwartzman phenomenon 10.0
244 liver disease 10.0
245 calciphylaxis 10.0
246 poliomyelitis 10.0
247 adjustment disorder 10.0
248 pleomorphic carcinoma 10.0
249 conjunctivitis 10.0
250 severe combined immunodeficiency 10.0
251 connective tissue disease 10.0
252 juvenile rheumatoid arthritis 10.0
253 chronic kidney disease 10.0
254 mucormycosis 10.0
255 ulcerative colitis 10.0
256 viral exanthem 10.0
257 perinatal necrotizing enterocolitis 10.0
258 encephalitis 10.0
259 bacterial conjunctivitis 10.0
260 polyarteritis nodosa 10.0
261 miliary tuberculosis 10.0
262 47,xyy 10.0
263 allergic angiitis 10.0
264 cytokine deficiency 10.0
265 exfoliative dermatitis 10.0
266 mollaret meningitis 10.0
267 pasteurella multocida infection 10.0
268 staphylococcal toxic shock syndrome 10.0
269 stenotrophomonas maltophilia infection 10.0
270 streptococcal group a invasive disease 10.0
271 systemic onset juvenile idiopathic arthritis 10.0
272 west nile virus encephalitis 10.0
273 west nile virus infection 10.0
274 headache 10.0
275 seizure disorder 10.0
276 severe hereditary thrombophilia due to congenital protein s deficiency 10.0
277 igg4-related ophthalmic disease 10.0
278 avascular necrosis 10.0
279 necrotizing soft tissue infection 10.0
280 pneumococcal meningitis 10.0
281 staphylococcal scarlet fever 10.0
282 thrombotic microangiopathy 10.0
283 esophageal varix 9.9 SERPINC1 SERPINA1 F3 F2
284 buerger disease 9.9 F2 APOH
285 porencephaly 9.9 F5 F2
286 hepatic vascular disease 9.9 SERPINC1 SERPINA1 F3 F2
287 livedoid vasculitis 9.9 SERPINF2 SERPINC1 F2 APOH
288 hemophilia b 9.9 SERPINC1 SERPINA1 F3 F2
289 sagittal sinus thrombosis 9.9 SERPINC1 F5 F3 F2
290 post-thrombotic syndrome 9.9 SERPINC1 F5 F3 F2
291 cerebral palsy 9.9 SERPINC1 PROC F5 F2
292 endocardium disease 9.8 SIGLEC5 SERPINC1 F3 F2
293 cecal disease 9.8 F3 F2
294 spinal cord infarction 9.8 SERPINC1 F5 F2 APOH
295 sudden sensorineural hearing loss 9.8 SERPINC1 F5 F2 APOH
296 prothrombin deficiency, congenital 9.8 SERPINC1 F5 F2 APOH
297 sneddon syndrome 9.8 SERPINC1 F5 F2 APOH
298 ischemic colitis 9.8 SERPINC1 F5 F2 APOH
299 retinal vascular occlusion 9.8 SERPINC1 F5 F2 APOH
300 retinal artery occlusion 9.8 SERPINC1 F5 F2 APOH
301 nonarteritic anterior ischemic optic neuropathy 9.8 SERPINC1 F5 F2 APOH
302 factor xii deficiency 9.8 SERPINC1 F5 F3 APOH
303 hepatic veno-occlusive disease 9.8 THBD SERPINC1 F3
304 hemoglobinuria 9.8 THBD SERPINC1 F2
305 paroxysmal nocturnal hemoglobinuria 9.8 THBD SERPINC1 F2
306 boutonneuse fever 9.8 THBD SERPINA1
307 factor viii deficiency 9.7 SIGLEC5 F5 F3 F2
308 cerebral sinovenous thrombosis 9.6 PROS1 F5 F3 F2 APOH
309 portal vein thrombosis 9.6 SERPINC1 PROC F5 F2 APOH
310 liver cirrhosis 9.6 SERPINF2 SERPINC1 SERPINA1 F3 F2
311 intracranial thrombosis 9.6 SERPINC1 F5 F3 F2 APOH
312 peripheral vertigo 9.6 SERPINC1 F5 F3 F2 APOH
313 antithrombin iii deficiency 9.6 SERPINC1 F5 F3 F2 APOH
314 factor v deficiency 9.6 F5 F3 F2 COX5A
315 central retinal vein occlusion 9.6 SERPINC1 F5 F3 F2 APOH
316 retinal vein occlusion 9.6 SERPINC1 F5 F3 F2 APOH
317 hemolytic-uremic syndrome 9.6 THBD SERPINC1 F3 F2
318 intracranial hypertension 9.6 SERPINC1 F5 F3 F2 APOH
319 budd-chiari syndrome 9.6 SERPINC1 F5 F3 F2 APOH
320 placenta disease 9.6 SERPINC1 F5 F3 F2 APOH
321 essential thrombocythemia 9.6 THBD SERPINC1 F3 F2
322 carotid artery occlusion 9.6 THBD F5 APOH
323 factor xiii deficiency 9.6 SERPINF2 SERPINC1 F5 F3 F2
324 patent foramen ovale 9.6 SERPINC1 F5 F3 F2 APOH
325 eclampsia 9.6 THBD SERPINC1 F2 APOH
326 homocystinuria 9.6 THBD SERPINC1 F5
327 blood platelet disease 9.5 SERPINC1 F3 F2 COX5A APOH
328 pulmonary hypertension 9.5 THBD SERPINC1 F3 F2
329 acute myocardial infarction 9.5 THBD SERPINF2 SERPINC1 F3
330 vein disease 9.5 SERPINC1 PROS1 PROC F5 F3 F2
331 polycythemia vera 9.5 THBD F5 F2
332 dysfibrinogenemia, congenital 9.4 THBD SERPINC1 F5 F2
333 varicose veins 9.4 THBD SERPINC1 F5 F2
334 legg-calve-perthes disease 9.4 THBD SERPINC1 F5 APOH
335 autoimmune disease of cardiovascular system 9.4 THBD SERPINC1 F3 F2 APOH
336 takayasu arteritis 9.4 THBD SERPINC1 F3 F2 APOH
337 factor xi deficiency 9.2 THBD SERPINC1 F5 F3 F2
338 peripheral vascular disease 9.2 THBD SERPINC1 F5 F3 F2
339 homocysteinemia 9.2 THBD SERPINC1 F5 F2 APOH
340 behcet syndrome 9.2 THBD SERPINC1 F5 F2 APOH
341 cerebrovascular disease 9.2 THBD PROCR F5 F2 APOH
342 placental abruption 9.0 THBD SERPINC1 PROC F5 F2 APOH
343 hellp syndrome 9.0 THBD SERPINC1 F5 F3 F2 APOH
344 pulmonary artery disease 8.7 THBD SERPINF2 SERPINC1 F5 F3 F2
345 pre-eclampsia 8.7 THBD SERPINF2 SERPINC1 F5 F3 F2
346 hemorrhagic disease 8.7 THBD SERPINF2 SERPINC1 SERPINA1 F5 F3
347 stroke, ischemic 8.5 THBD SERPINF2 SERPINC1 PROCR F5 F3
348 inherited blood coagulation disease 8.2 THBD SIGLEC5 SERPINC1 PROC F5 F3
349 myocardial infarction 8.0 THBD SERPINF2 SERPINC1 PROCR F5 F3
350 blood coagulation disease 7.9 THBD SIGLEC5 SERPINF2 SERPINC1 F5 F3

Graphical network of the top 20 diseases related to Purpura Fulminans:



Diseases related to Purpura Fulminans

Symptoms & Phenotypes for Purpura Fulminans

GenomeRNAi Phenotypes related to Purpura Fulminans according to GeneCards Suite gene sharing:

26 (showing 1, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased replication of vaccinia virus (VACV) GR00362-A 8.62 PROC THBD

MGI Mouse Phenotypes related to Purpura Fulminans:

45 (showing 5, show less)
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.97 ADAM10 F2 F3 F5 PROC PROCR
2 homeostasis/metabolism MP:0005376 9.9 ADAM10 APOH F2 F3 F5 PROC
3 embryo MP:0005380 9.86 ADAM10 F2 F3 F5 PROCR PROS1
4 mortality/aging MP:0010768 9.7 ADAM10 APOH F2 F3 F5 PROC
5 normal MP:0002873 9.17 ADAM10 F2 F3 PROCR PROS1 SERPINA1

Drugs & Therapeutics for Purpura Fulminans

Drugs for Purpura Fulminans (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 9, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Drotrecogin alfa activated Phase 3
2 Anti-Infective Agents Phase 3
3
Hydrocortisone Approved, Vet_approved Phase 2 50-23-7 5754
4
Hydrocortisone acetate Approved, Vet_approved Phase 2 50-03-3
5 Hydrocortisone 17-butyrate 21-propionate Phase 2
6 Hydrocortisone-17-butyrate Phase 2
7 Anti-Inflammatory Agents Phase 2
8 Hydrocortisone hemisuccinate Phase 2
9 Natriuretic Peptide, Brain

Interventional clinical trials:

(showing 5, show less)
# Name Status NCT ID Phase Drugs
1 Investigation of the Efficacy and Safety of Drotrecogin Alfa (Activated) in Pediatric Severe Sepsis Completed NCT00049764 Phase 3 Drotrecogin alfa (activated);Placebo
2 Evaluation of Corticosteroid Therapy in Childhood Severe Sepsis (Steroids in Paediatric Sepsis, StePS) - a Randomised Pilot Study Completed NCT00732277 Phase 2 hydrocortisone
3 Septic cArdiac Deficiency and MenIngococcal seveRe Sepsis Unknown status NCT02041663
4 Short and Long-term Outcomes of Purpura Fulminans in Adults Completed NCT03216577
5 Sepsis-Associated Purpura Fulminans International Registry - Europe Recruiting NCT02238795

Search NIH Clinical Center for Purpura Fulminans

Cochrane evidence based reviews: purpura fulminans

Genetic Tests for Purpura Fulminans

Anatomical Context for Purpura Fulminans

MalaCards organs/tissues related to Purpura Fulminans:

40
Skin, Brain, Liver, Endothelial, Bone, Testes, T Cells

Publications for Purpura Fulminans

Articles related to Purpura Fulminans:

(showing 939, show less)
# Title Authors PMID Year
1
Fulminant sepsis/meningitis due to Haemophilus influenzae in a protein C-deficient heterozygote treated with activated protein C therapy. 54 61
18751723 2009
2
Pneumococcal purpura fulminans successfully treated with activated protein C. 61 54
18791506 2008
3
Modern concepts of the diagnosis and treatment of purpura fulminans. 54 61
18652566 2008
4
Hereditary angioedema associated with heterozygous factor V Leiden mutation in a patient with Purpura fulminans. 54 61
17068406 2007
5
Treatment of acute infectious purpura fulminans with activated protein C. 61 54
16820663 2006
6
[Sepsis-associated coagulation disorders]. 61 54
15924156 2005
7
Purpura fulminans due to Staphylococcus aureus. 54 61
15824983 2005
8
Homozygous type I Protein C deficiency in neonatal purpura fulminans with a novel frame-shift deletion of 10 base pairs in exon 8 of PROC gene. 61 54
15748260 2005
9
Massive soft tissue infections: necrotizing fasciitis and purpura fulminans. 61 54
15715517 2005
10
[Recombinant human activated protein C in the treatment of children with meningococcal purpura fulminans]. 61 54
15469811 2004
11
Importance of hemostatic gene polymorphisms for susceptibility to and outcome of severe sepsis. 54 61
15118537 2004
12
Purpura fulminans due to Streptococcus pneumoniae sepsis following gastric bypass. 61 54
15186640 2004
13
Activated protein C concentrate reverses purpura fulminans in severe genetic protein C deficiency. 61 54
14707707 2004
14
Combined antithrombin and protein C supplementation in meningococcal purpura fulminans: a pharmacokinetic study. 54 61
12761614 2003
15
Purpura fulminans in a child with combined heterozygous prothrombin G20210A and factor V Leiden mutations. 61 54
12601492 2003
16
Severe protein S deficiency associated with heterozygous factor V Leiden mutation in a child with purpura fulminans. 54 61
12687747 2003
17
[Physiopathology and curative treatment of meningococcal diseases: current aspects]. 61 54
12504371 2002
18
Plasma exchange as a source of protein C for acute onset protein C pathway failure. 61 54
11886399 2002
19
An open-label study of the role of adjuvant hemostatic support with protein C replacement therapy in purpura fulminans-associated meningococcemia. 54 61
11090052 2000
20
Severe digital necrosis in an elderly patient with heterozygous factor V Leiden mutation. 54 61
11122039 2000
21
A case of purpura fulminans is caused by homozygous delta8857 mutation (protein C-nagoya) and successfully treated with activated protein C concentrate. 61 54
10997987 2000
22
Postinfection purpura fulminans in a patient heterozygous for prothrombin G20210A and acquired protein S resistance. 61 54
10599098 1999
23
Effect of the Factor V Leiden mutation on the severity of meningococcal disease. 54 61
10530586 1999
24
Adult purpura fulminans and digital necrosis associated with sepsis and the factor V mutation. 54 61
9846775 1998
25
Varicella purpura fulminans associated with heterozygosity for factor V leiden and transient protein S deficiency. 54 61
9794956 1998
26
Homozygous Factor V Leiden mutation in a child with meningococcal purpura fulminans. 54 61
9469407 1998
27
[Purpura fulminans in the newborn. Report of two cases successfully treated with heparin and antithrombin III]. 61 54
9577159 1997
28
Purpura fulminans induced by disseminated intravascular coagulation following infection in 2 unrelated children with double heterozygosity for factor V Leiden and protein S deficiency. 54 61
9241737 1997
29
Neonatal purpura fulminans in association with factor V R506Q mutation. 61 54
8627449 1996
30
Meningococcal purpura fulminans treated with antithrombin III concentrate: what is the optimal replacement therapy? 54 61
7848164 1994
31
A homozygous deletion/insertion mutation in the protein C (PROC) gene causing neonatal Purpura fulminans: prenatal diagnosis in an at-risk pregnancy. 61 54
7841323 1994
32
Meningococcemia and purpura fulminans in adults: acute deficiencies of proteins C and S and early treatment with antithrombin III concentrates. 61 54
2139671 1990
33
Capnocytophagia canimorsus - Severe sepsis in a previously well individual with no evidence of a cat or dog bite. A case report. 61
32461803 2020
34
Septic Shock and Purpura Fulminans Due to Streptococcus pneumoniae Bacteremia in an Unvaccinated Immunocompetent Adult: Case Report and Review. 61
32513908 2020
35
Epidemiology of Community-Onset Severe Bacterial Infections in Children and Its Evolution: A Population-Based Study in France. 61
32224829 2020
36
[Acute fever with rash, necrosis, and bullae in both lower extremities in a 12-year-old girl]. 61
32571467 2020
37
Acute Purpura Fulminans - a rare cause of skin necrosis: A single institution clinicopathological experience. 61
32356378 2020
38
[Treatment failure after postinfectious purpura fulminans despite interdisciplinary surgical and intensive medical therapy]. 61
32055865 2020
39
Purpuric Epiglottic Lesion in Purpura Fulminans Form of Meningococcemia. 61
32293909 2020
40
Anti-interleukin-6 receptor therapy-induced cutaneous symptoms resembling purpura fulminans in a patient with seropositive rheumatoid arthritis. 61
32277528 2020
41
Retiform purpura: Workup and therapeutic considerations in select conditions. 61
31479690 2020
42
Meningococcal disease: A paradigm of type-IV pilus dependent pathogenesis. 61
32185901 2020
43
Neisseria meningitidis Induced Fatal Waterhouse-Friderichsen Syndrome in a Patient Presenting With Disseminated Intravascular Coagulation and Multiple Organ Failure. 61
32192003 2020
44
Pneumococcal Sepsis-Induced Purpura Fulminans in an Asplenic Adult Patient with Disseminated Intravascular Coagulation. 61
32223817 2020
45
Successful treatment of meningococcal bacteremia using oral doxycycline: A case report. 61
31887457 2020
46
Clinical manifestations of invasive meningococcal disease in Victoria with the emergence of serogroup W and serogroup Y Neisseria meningitidis. 61
32043702 2020
47
Pneumococcal purpura fulminans in asplenic or hyposplenic patients: a French multicenter exposed-unexposed retrospective cohort study. 61
32102696 2020
48
Vasculitis with nonpalpable purpura resembling purpura fulminans. 61
31776714 2020
49
Development of Bilateral Heterotopic Ossification After Survival of Life Threatening Purpura Fulminans. 61
32133255 2020
50
Purpura Fulminans: a Rare but Fierce Presentation of Pneumococcal Sepsis. 61
32015972 2020
51
Uncommon Location of Purpura Fulminans: Case Report and Literature Review. 61
32095125 2020
52
Fulminant Neisseria meningitidis septicaemia with purpura fulminans requiring limb amputation. 61
31879595 2020
53
The rash that becomes purpuric, petechial, hemorrhagic, or ecchymotic. 61
32197746 2020
54
Compartment syndrome due to Capnocytophaga canimorsus infection: a case report. 61
31988786 2020
55
[Inflammatory myopathy following acute meningoccemia in a properdin-deficient patient: A case report]. 61
31735371 2020
56
The surgical strategy of Purpura fulminans triggered by pyothorax associated with lung cancer. 61
32002466 2020
57
Vaccine-preventable meningitis in French children with incorrect vaccination status from 2011 to 2013. 61
31776077 2020
58
Streptococcus pyogenes purpura fulminans and septic shock: A case highlighting the ethical considerations of high-risk extracorporeal membrane oxygenation. 61
31984828 2020
59
Community-acquired bacterial meningitis in adults: in-hospital prognosis, long term disability and determinants of outcome in a multicentre prospective cohort. 61
31927117 2020
60
Streptococcal toxic shock syndrome in a returning traveller. 61
30369302 2019
61
Idiopathic purpura fulminans. 61
31801806 2019
62
Extracorporeal Membrane Oxygenation in Adult Patients With Purpura Fulminans. 61
31738265 2019
63
Pediatric Cutaneous Emergencies and their Outcome: Study from a Tertiary Care Center in South India. 61
31807443 2019
64
Disseminated Intravascular Coagulation With Purpura Fulminans Presentation of Acute Promyelocytic Leukemia. 61
31763615 2019
65
Prothrombotic and Proinflammatory Activities of the β-Hemolytic Group B Streptococcal Pigment. 61
31743913 2019
66
Hereditary protein C deficiency caused by novel compound heterozygous mutants in a Chinese pedigree: A case report. 61
31521534 2019
67
Protein C Deficiency. 61
30702334 2019
68
Diagnostic yield of lumbar puncture in adult patients with purpura fulminans. 61
31278443 2019
69
Early fasciotomies and plastic-surgical reconstruction may enhance preservation of functional extremity length in purpura fulminans. 61
31524150 2019
70
The color of skin: purple diseases of the skin, nails, and mucosa. 61
31896408 2019
71
A Multidisciplinary Approach to the Management of Severe Purpura Fulminans in a Burn Center: A Case Series. 61
31646137 2019
72
A unique fatal case of Waterhouse-Friderichsen syndrome caused by Proteus mirabilis in an immunocompetent subject: Case report and literature analysis. 61
31441842 2019
73
Long-term Quality of Life in Adult Patients Surviving Purpura Fulminans: An Exposed-Unexposed Multicenter Cohort Study. 61
30335142 2019
74
Catastrophic Antiphospholid Syndrome - An Unusual Case Report. 61
31435147 2019
75
Management of severe congenital protein C deficiency with a direct oral anticoagulant, edoxaban: A case report. 61
30835920 2019
76
Purpura in the Emergency Room: Two Cases of Sepsis with Cutaneous Manifestations. 61
31467810 2019
77
Purpura fulminans manifesting with Staphylococcus aureus endocarditis: a case report. 61
31449632 2019
78
Acute Infectious Purpura Fulminans Caused by Klebsiella oxytoca. 61
30713331 2019
79
Unusual purpura fulminans after heart transplantation. 61
30191293 2019
80
Purpura fulminans from reduced protein S following cytomegalovirus and varicella infection. 61
30585353 2019
81
Management of purpura fulminans skin lesions in a premature neonate with sepsis: a case study. 61
30975056 2019
82
Severe cytokine release syndrome resulting in purpura fulminans despite successful response to nivolumab therapy in a patient with pleomorphic carcinoma of the lung: a case report. 61
30944043 2019
83
Renal histological findings in a patient with acute renal injury associated with purpura fulminans: a case report. 61
30222177 2019
84
A Genetic Origin? Purpura Fulminans. 61
30367859 2019
85
Meningococcal purpura fulminans and severe myocarditis with clinical meningitis but no meningeal inflammation: a case report. 61
30871501 2019
86
Four-extremity amputation following disseminated intravascular coagulation and purpura fulminans. 61
30898966 2019
87
Poor adherence to population-based vaccination in two counties after meningococcal B:14:P1.7,16 outbreak: an illustration of the growing vaccine hesitancy in France. 61
30617005 2019
88
Being Licked by a Dog Can Be Fatal: Capnocytophaga canimorsus Sepsis with Purpura Fulminans in an Immunocompetent Man. 61
31742204 2019
89
Genotypic and phenotypic character of Chinese neonates with congenital protein C deficiency: a case report and literature review. 61
31592240 2019
90
Acute infectious purpura fulminans with Enterobacter aerogenes post-neurosurgery. 61
30911465 2019
91
Neonatal Skin Emergencies. 61
30653641 2019
92
Mowat-Wilson Syndrome Presenting With Purpura Fulminans. 61
30573661 2019
93
[Acute hemorrhagic edema of infancy]. 61
31692796 2019
94
[Acute hemorrhagic edema of infancy]. 61
31692802 2019
95
Surgical outcomes in adults with purpura fulminans: a systematic review and patient-level meta-synthesis. 61
31641673 2019
96
Identification of PROS1 as a Novel Candidate Gene for Juvenile Retinitis Pigmentosa. 61
32489947 2019
97
[Meningococcus purpura fulminans, a partially solved mystery]. 61
30623761 2018
98
Sepsis-Associated Purpura Fulminans Due to Klebsiella Oxytoca. 61
30602411 2018
99
Escherichia coli Bacteremia-induced Purpura Fulminans: A Case Report. 61
30723639 2018
100
Persistence of endothelial thrombomodulin in a patient with infectious purpura fulminans treated with protein C concentrate. 61
30396911 2018
101
Acquired Versus Congenital Neonatal Purpura Fulminans: A Case Report and Literature Review. 61
29683961 2018
102
[Purpura fulminans related to paroxysmal nocturnal haemoglobinuria: a case report and literatures review]. 61
30486589 2018
103
Therapeutic response to glucocorticoids, anticoagulation and plasma exchange in a patient with primary antiphospholipid syndrome presenting with purpura fulminans. 61
30290709 2018
104
Purpura fulminans with Lemierre's syndrome caused by Gemella bergeri and Eikenella corrodens: a case report. 61
30340466 2018
105
Purpura fulminans-like lesions in antiphospholipid syndrome with endothelial C3 deposition. 61
30364713 2018
106
Invasive Meningococcal Disease due to group C N. meningitidis ST11 (cc11): The Tuscany cluster 2015-2016. 61
30172636 2018
107
Clinical spectrum and short-term outcome of adult patients with purpura fulminans: a French multicenter retrospective cohort study. 61
30128591 2018
108
Recurrent invasive group A streptococcal infection with four-limb amputation in an immunocompetent child. 61
30061131 2018
109
Streptococcus pyogenes-purpura fulminans as an invasive form of group A streptococcal infection. 61
29986727 2018
110
Purpura fulminans - It's Not Always Sepsis. 61
29381878 2018
111
Purpura fulminans in congenital protein C deficiency successfully treated with fresh frozen plasma and thrombomodulin. 61
29265490 2018
112
Rare presentation of rickettsial infection as purpura fulminans: a case report. 61
29801512 2018
113
Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel. 61
29664383 2018
114
Fatal meningococcal septicemia without meningeal signs, contribution of the peripheral smear in diagnosis: Report of a case. 61
29676380 2018
115
An ADAM-10 dependent EPCR shedding links meningococcal interaction with endothelial cells to purpura fulminans. 61
29630665 2018
116
Purpura Fulminans: Mechanism and Management of Dysregulated Hemostasis. 61
29157918 2018
117
Slow Elevation in Protein C Activity without a PROC Mutation in a Neonate with Intracranial Hemorrhage. 61
29657898 2018
118
Purpura fulminans causing acute cortical necrosis in postpartum period. 61
29593006 2018
119
Neonatal Purpura Fulminans, a rare genetic disorder due to protein C deficiency: A case report. 61
29540887 2018
120
A novel compound heterozygous mutations in protein C gene causing neonatal purpura fulminans. 61
29356699 2018
121
Acute infectious purpura fulminans secondary to a dog bite. 61
29437318 2018
122
Homozygous protein C deficiency presenting as neonatal purpura fulminans: management with fresh frozen plasma, low molecular weight heparin and protein C concentrate. 61
29270858 2018
123
Incidences, risk factors and outcomes of neonatal thromboembolism. 61
28110589 2018
124
Acute Kidney Injury in a Case of Purpura Fulminans Developing Secondary to Antithrombin 3 Deficiency. 61
29540648 2018
125
Sloughing skin in intravenous drug user. 61
29942754 2018
126
Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature. 61
30225149 2018
127
Heartfelt sepsis: microvascular injury due to genomic storm. 61
29974447 2018
128
Coexistence of Kasabach-Merritt Syndrome and placental chorioangioma in a premature infant. 61
29991142 2018
129
Lethal End of Spectrum of Clots-Thrombotic Storm. 61
29977623 2018
130
[Maternal deaths due to infectious cause, results from the French confidential enquiry into maternal deaths, 2010-2012]. 61
29108905 2017
131
Purpura fulminans due to pneumococcal infection. 61
29264090 2017
132
Perioperative management of severe congenital protein C deficiency. 61
28737523 2017
133
[Acute hemorrhagic edema of infancy associated with Coxsackie virus infection]. 61
29174007 2017
134
Peripheral blood vessels are a niche for blood-borne meningococci. 61
29099305 2017
135
Myocarditis and purpura fulminans in meningococcaemia. 61
29024990 2017
136
A novel compound heterozygous form of severe protein C deficiency causing bleeding without purpura fulminans. 61
28485122 2017
137
Skin biopsy polymerase chain reaction for rapid microbiological diagnosis in patients with purpura fulminans. 61
28369801 2017
138
Purpura Fulminans: A rare presentation of Streptococcus Pneumoniae infection. 61
29054893 2017
139
Mutilating Purpura Fulminans in an Adult with Meningococcal Sepsis. 61
28915308 2017
140
Acute Cutaneous Necrosis: A Guide to Early Diagnosis and Treatment. 61
28470091 2017
141
Reconstruction of Near-Total Loss of the Upper and Lower Lips due to Purpura Fulminans with Local Tissue and a Dual-Skin Paddled Anterolateral Thigh Flap. 61
29062669 2017
142
Purpura Fulminans as the presenting manifestation in a patient with homozygous methylenetetrahydrofolate reductase gene mutation. 61
28612584 2017
143
Severe Neonatal Purpura Fulminans Caused by Staphylococcus aureus. 61
27449990 2017
144
Purpura Fulminans in Acute Meningococcemia. 61
28236134 2017
145
The clinical presentation and genotype of protein C deficiency with double mutations of the protein C gene. 61
28111891 2017
146
Evolution of Purpura Fulminans. 61
28564574 2017
147
Purpura fulminans mimicking toxic epidermal necrolysis - additional value of 16S rRNA sequencing and skin biopsy. 61
28522775 2017
148
Neisseria meningitidis and purpura fulminans in a woman with chronic liver disease. 61
28346185 2017
149
Pathogenesis of meningococcal purpura fulminans. 61
28334263 2017
150
Widespread subcutaneous necrosis in spotted fever group Rickettsioses from the coastal belt of Sri Lanka- a case report. 61
28412927 2017
151
Inactivation of human coagulation factor X by a protease of the pathogen Capnocytophaga canimorsus. 61
28029716 2017
152
A delayed presentation of homozygous protein C deficiency in a series of children: a report on two molecular defects. 61
28265398 2017
153
Challenging Airway Secondary to Purpura Fulminans With Face and Neck Bullae in a Premature Infant: A Case Report. 61
28195860 2017
154
Penile necrosis secondary to purpura fulminans: a case report and review of literature. 61
28479975 2017
155
Purpura Fulminans Associated with Overwhelming Postsplenectomy Infection. 61
28090064 2017
156
Disseminated intravascular coagulation in an under-recognised zoonotic infection. 61
29072871 2017
157
Indian Tick Typhus Presenting as Purpura Fulminans with Review on Rickettsial Infections. 61
28216718 2017
158
Protein C Deficiency Caused by a Novel Mutation in the PROC Gene in an Infant with Delayed Onset Purpura Fulminans. 61
29082047 2017
159
Genetic Risk Factors in Venous Thromboembolism. 61
27638626 2017
160
Delayed Surgical Debridement and Use of Semiocclusive Dressings for Salvage of Fingers After Purpura Fulminans. 61
28149224 2016
161
[A case report of protein-C deficency related neonatal purpura fulminans]. 61
27938599 2016
162
Anticoagulants in dermatology. 61
27320765 2016
163
A Novel Protein C Mutation Causing Neonatal Purpura Fulminans. 61
27889735 2016
164
Loss of orofacial tissue secondary to septic shock caused by Streptococcus pneumoniae. 61
27006285 2016
165
A Fatal Case of Invasive Infection Caused By W135 Neisseria meningitidis in a Vaccinated French Soldier. 61
27849512 2016
166
Experimental Evidence of Bacterial Colonization of Human Coronary Microvasculature and Myocardial Tissue during Meningococcemia. 61
27481255 2016
167
[Contribution of the physical and rehabilitation medicine in pediatric plastic surgery]. 61
27499255 2016
168
[Management of purpura fulminans lesions in children]. 61
27289551 2016
169
Purpura fulminans related to paroxysmal nocturnal haemoglobinuria. 61
27046923 2016
170
Comprehensive Identification of Meningococcal Genes and Small Noncoding RNAs Required for Host Cell Colonization. 61
27486197 2016
171
Severe Congenital Protein C Deficiency: Practical Aspects of Management. 61
27138381 2016
172
Efficacy and safety of protein C concentrate to treat purpura fulminans and thromboembolic events in severe congenital protein C deficiency. 61
27052576 2016
173
Scrub typhus and spotted fever among hospitalised children in South India: Clinical profile and serological epidemiology. 61
27514949 2016
174
Streptococcus pneumoniae-induced purpura fulminans. 61
27083982 2016
175
Five-year analysis of rickettsial fevers in children in South India: Clinical manifestations and complications. 61
27367015 2016
176
Purpura fulminans and severe sepsis due to Pasteurella multocida infection in an immunocompetent patient. 61
27298290 2016
177
Lifetime cost of meningococcal disease in France: Scenarios of severe meningitis and septicemia with purpura fulminans. 61
26688376 2016
178
Thrombosis in newborn infants. 61
27079395 2016
179
Overwhelming Postsplenectomy Infection: A Prospective Multicenter Cohort Study. 61
26703862 2016
180
[Clinical aspects and treatment of invasive meningococcal infections] 61
30512636 2016
181
Case 15: use as an instillation solution with NPWT. 61
26949859 2016
182
Complete Genome Sequence of Streptococcus pneumoniae Serotype 19A, a Blood Clinical Isolate from Northeast Mexico. 61
27034499 2016
183
Acute infectious purpura fulminans caused by group A β-hemolytic Streptococcus: An uncommon organism. 61
27057503 2016
184
Purpura fulminans associated with acute West Nile virus encephalitis. 61
26686320 2016
185
Fetal hydrocephalus and neonatal stroke as the first presentation of protein C deficiency. 61
26250584 2016
186
Pneumococcal Sepsis Complicated by Splenic Abscesses and Purpura Fulminans in a 15-Month-Old Child: Case Report and Review of the Literature. 61
27006958 2016
187
Fatal purpura fulminans and Waterhouse-Friderichsen syndrome from fulminant Streptococcus pneumoniae sepsis in an asplenic young adult. 61
27583208 2016
188
Purpura fulminans secondary to rickettsial infections: A case series. 61
26955583 2016
189
Strongyloides stercoralis hyperinfection in patient with autoimmune hepatitis and purpura fulminans. 61
26955218 2016
190
Successful Corticosteroid Treatment for Purpura Fulminans Associated with Quinolone. 61
27746448 2016
191
Purpura fulminans in the setting of Escherichia coli septicemia. 61
26761941 2015
192
Purpura Fulminans Secondary to Rickettsial Infection: A Case Report. 61
26673422 2015
193
Purpura Fulminans Due to Acquired Protein C Deficiency. 61
26677306 2015
194
Purpura Fulminans in Toxic Epidermal Necrolysis: Case Report and Review. 61
25412057 2015
195
Purpura fulminans 10 years after contaminated cocaine use. 61
26028121 2015
196
[Neonatal purpura fulminans without sepsis due to a severe congenital protein C deficiency]. 61
26228809 2015
197
Neonatal purpura fulminans due to protein C deficiency. 61
25783192 2015
198
Staphylococcal Purpura Fulminans: Report of a Case. 61
25099358 2015
199
[Necrosis of maxilla secondary to purpura fulminans. A case report]. 61
25986489 2015
200
Purpura fulminans on the nose with septic abortion. 61
25617262 2015
201
Successful living domino liver transplantation in a child with protein C deficiency. 61
25712501 2015
202
Bilateral symmetrical digital gangrene of upper and lower limbs due to purpura fulminans caused by Streptococcus pyogenes: A rare entity. 61
25983440 2015
203
Molecular characterization of p.Asp77Gly and the novel p.Ala163Val and p.Ala163Glu mutations causing protein C deficiency. 61
25618265 2015
204
Angioimmunoblastic t-cell lymphoma presenting as purpura fulminans. 61
25750965 2015
205
Role of protein S deficiency in children with venous thromboembolism. An observational international cohort study. 61
25272994 2015
206
Septic vasculitis and vasculopathy in some infectious emergencies: the perspective of the histopathologist. 61
25592669 2015
207
Rash, disseminated intravascular coagulation and legionella: Episode 10 and a rewind into the past. 61
26236615 2015
208
Infectious purpura fulminans. 61
25857509 2015
209
Prenatal genetic testing for familial severe congenital protein C deficiency. 61
27081530 2015
210
Pravastatin-induced rhabdomyolysis and purpura fulminans in a patient with chronic renal failure. 61
25644555 2015
211
Purpura Fulminans due to Enterobacter cloacae. 61
26370876 2015
212
Skin Necrosis and Purpura Fulminans in Children With and Without Thrombophilia--A Tertiary Center's Experience. 61
26436558 2015
213
Group A Escherichia coli-related purpura fulminans: an unusual manifestation due to an unusual strain? 61
25232165 2014
214
Two cases of meningococcal purpura fulminans: the 'less is more' approach. 61
23323934 2014
215
[Purpura fulminans of the adult--a hematological emergency]. 61
25469695 2014
216
Purpura fulminans managed with multi-limb amputation: substituted judgment and surrogate decision-making in the surgical management of necrotizing soft tissue infections. 61
25494230 2014
217
Clinical and laboratory characteristics of children with venous thromboembolism and protein C-deficiency: an observational Israeli-German cohort study. 61
25039884 2014
218
[Sepsis-associated Purpura Fulminans International Registry--Europe (SAPFIRE)]. 61
25348051 2014
219
Purpura fulminans and late onset group B streptococcal sepsis in a premature twin. 61
25452884 2014
220
Long-term follow-up of homozygote protein C deficiency after multimodal therapy. 61
24136027 2014
221
Invasive meningococcal disease: a disease of the endothelial cells. 61
25178566 2014
222
Bilateral torsion of testes with purpura fulminans. 61
25228613 2014
223
Purpura fulminans secondary to rickettsia in a child: a case report. 61
25253220 2014
224
Streptococcus pneumoniae-induced purpura fulminans in a woman with functional asplenia. 61
25060091 2014
225
Indian tick typhus presenting as Purpura fulminans. 61
25097365 2014
226
Continuous subcutaneous infusion of protein C concentrate using an insulin pump in a newborn with congenital protein C deficiency. 61
24509341 2014
227
Bilateral Total Knee Arthroplasty with Extensor Mechanism Allografts and Flap Reconstructions After Soft-Tissue Joint Destruction from Purpura Fulminans: A Case Report. 61
29252347 2014
228
A novel mutation in protein C gene (PROC) causing severe phenotype in neonatal period. 61
24115609 2014
229
Acute infectious purpura fulminans due to probable spotted fever. 61
24823524 2014
230
Purpura fulminans after therapeutic hypothermia in an asphyxiated neonate with streptococcemia. 61
23839905 2014
231
[Image of the month. Purpura fulminans caused by meningococcemia]. 61
24830209 2014
232
[Impact of corticosteroids in the immediate management of invasive meningococcal disease associated with hyperinvasive strains of the ST-11 clonal complex in children]. 61
24485864 2014
233
Sepsis-induced purpura fulminans caused by Pasteurella multocida. 61
24554680 2014
234
A life threatening rash, an unexpected cause. 61
25431693 2014
235
Molecular analysis of staphylococcal superantigens. 61
24085696 2014
236
Coagulopathy in malaria. 61
24099998 2014
237
A case of purpura fulminans caused by Hemophilus influenzae complicated by reversible cardiomyopathy. 61
25520829 2014
238
Identification of differentially expressed serum proteins in infectious purpura fulminans. 61
24659849 2014
239
Hyperbaric oxygen: a useful adjunct for purpura fulminans: case report and review of the literature. 61
24649717 2014
240
Fatal purpura fulminans and septic shock in asplenic patient with Streptococcus pneumoniae bacteremia. 61
24407746 2014
241
From the toe to the head: metastatic endophalmitis following staphylococcal purpura fulminans. 61
24231686 2014
242
Pneumococcal sepsis-induced purpura fulminans in an asplenic adult patient without disseminated intravascular coagulation. 61
24185261 2013
243
Limb fitting for quadruple amputees: report of two cases of symmetrical peripheral gangrene caused by pneumococcal purpura fulminans. 61
23558402 2013
244
A novel mutation c.1048A>T at codon 350(Lys>Stop) in PROC gene causing neonatal purpura fulminans. 61
24158118 2013
245
Anticoagulant treatment with rivaroxaban in severe protein S deficiency. 61
24144709 2013
246
Purpura fulminans: an unusual complication of malaria. 61
24076110 2013
247
Meningococcal interaction to microvasculature triggers the tissular lesions of purpura fulminans. 61
23840047 2013
248
Diagnostic value of polymerase chain reaction analysis of skin biopsies in purpura fulminans. 61
23834254 2013
249
Purpura Fulminans Associated with Hemiparesis Following Measles Infection in a Nigerian Girl: A Case Report. 61
26664850 2013
250
Protein-C deficiency presenting as pulmonary embolism and myocardial infarction in the same patient. 61
24228720 2013
251
Management of septic skin necroses. 61
24008550 2013
252
The skin and hypercoagulable states. 61
23582572 2013
253
Assessment of the interplay between blood and skin vascular abnormalities in adult purpura fulminans. 61
23924269 2013
254
Purpura fulminans associated with Streptococcus pneumoniae septicemia in an asplenic pediatric patient. 61
23985086 2013
255
Inherited thrombophilia in children. 61
23890023 2013
256
Purpura fulminans caused by meningococcemia in an infant. 61
23921694 2013
257
Antiphospholipid antibody syndrome presenting with purpura fulminans. 61
23869929 2013
258
Meningococcal sepsis and purpura fulminans: the surgical perspective. 61
23389283 2013
259
Pathogenesis of meningococcemia. 61
23732856 2013
260
Protein C deficiency as the major cause of thrombophilias in childhood. 61
23521084 2013
261
Paediatric presentation and outcome of congenital protein C deficiency in Japan. 61
23379934 2013
262
[Purpura fulminans, venous thrombosis and constitutional thrombophilia in an infant]. 61
23566584 2013
263
Invasive meningococcal infection: analysis of 110 cases from a tertiary care centre in North East India. 61
22821284 2013
264
Plastic surgical treatment of purpura fulminans: Long-term follow-up of two patients. 61
23210495 2013
265
Primary meningococcal arthritis leading to Neisseria meningitidies purpura fulminans. 61
23599862 2013
266
Neonatal purpura fulminans due to methicillin resistant Staphylococcus aureus. 61
22276732 2013
267
Purpura fulminans in a patient with paroxysmal nocturnal haemoglobinuria. 61
23324094 2013
268
Purpura fulminans in an acute preterm neonate. 61
23250966 2013
269
Neonatal purpura fulminans manifestation in early-onset group B Streptococcal infection. 61
23970945 2013
270
Literature review and outcome of classic galactosemia diagnosed in the neonatal period. 61
24273939 2013
271
Spectrum of pediatric dermatological emergencies at a tertiary care hospital in India: a descriptive study. 61
22471326 2013
272
[Protein C deficiency in patient with sepsis-associated disseminated intravascular coagulation and deep vein thrombosis]. 61
23381714 2013
273
Toxic shock syndrome due to group A beta-hemolytic streptococcus presenting with purpura fulminans and limb ischemia in a pediatric patient treated with early microsurgical arteriolysis. 61
23331831 2013
274
Purpura fulminans in a patient with mixed connective tissue disease. 61
23370948 2013
275
Purpura Fulminans following Thermal Injury. 61
23762660 2013
276
Febrile urticaria in a family: uncommon manifestation of a common disease. 61
23276745 2012
277
Purpura fulminans from meningococcemia mimicking Stevens-Johnson syndrome in an adult patient taking etanercept. 61
23247497 2012
278
Purpura fulminans in Neisseria meningitidis B as presenting feature of multiple myeloma. 61
22897973 2012
279
Purpura fulminans in a child: a case report. 61
23373061 2012
280
Purpura fulminans in a child due to Neisseria meningitidis. 61
22718363 2012
281
Catheter-directed thrombolysis in a patient with purpura fulminans. 61
23089413 2012
282
A case of fulminant varicella infection with purpura fulminans, hepatitis, and rhabdomyolysis. 61
23248376 2012
283
Cerebral venous sinus thrombosis: association with primary varicella zoster virus infection. 61
22682971 2012
284
Testing for heritable thrombophilia in children at Starship Children's Hospital: an audit of requests between 2004 and 2009. 61
22900528 2012
285
Pressure ulcers and risk assessment in severe burns. 61
22964549 2012
286
Microparticles and infectious diseases. 61
22766273 2012
287
Two cases of infectious purpura fulminans and septic shock caused by Capnocytophaga canimorsus transmitted from dogs. 61
22497463 2012
288
[Fulminant Neisseria meningitidis B revealing multiple myeloma]. 61
22796619 2012
289
Hematological features of pediatric systemic lupus erythematosus: suggesting management strategies in children. 61
22495873 2012
290
A case of purpura fulminans arising from cryptococcosis. 61
22753692 2012
291
Purpura fulminans caused by community-associated methicillin-resistant Staphylococcus aureus. 61
21641144 2012
292
[Purpura fulminans: functional results in two paediatric patients after suffering multiple amputations]. 61
23594852 2012
293
Anaesthetic significance and management of a child with neonatal purpura fulminans. 61
22923829 2012
294
[Case report: A case of invasive pneumococcal disease with purpura fulminans and Waterhouse-Friderichsen syndrome]. 61
22693858 2012
295
Musculoskeletal sequelae of Varicella-zoster infection: two case reports. 61
22555234 2012
296
Outbreak of Neisseria meningitidis C in workers at a large food-processing plant in Brazil: challenges of controlling disease spread to the larger community. 61
21875453 2012
297
Protein C anticoagulant and cytoprotective pathways. 61
22477541 2012
298
Spectrum of purpura fulminans: report of three classical prototypes and review of management strategies. 61
22421668 2012
299
[Cerebral trunk abscess due to Neisseria meningitidis in a 28-year-old immunocompetent patient]. 61
22284670 2012
300
Nose and upper lip reconstruction for purpura fulminans. 61
21795130 2012
301
Photoclinic. Streptococcal purpura fulminans. 61
22292586 2012
302
Purpura Fulminans Secondary to Streptococcus pneumoniae Meningitis. 61
22567489 2012
303
[Post-varicella cerebral thrombophlebitis with anti-protein S: report of a pediatric case]. 61
22294143 2012
304
Diagnosis and management of neonatal purpura fulminans. 61
21839696 2011
305
Treatment of MRSA soft tissue infections: an overview. 61
22196904 2011
306
Purpura fulminans: recognition, diagnosis and management. 61
21233082 2011
307
Atypical presentation of purpura fulminans following sepsis in an adult. 61
22675087 2011
308
Atypical presentation of fatal meningococcemia: peritonitis and paradoxical centrifugal purpura fulminans of late onset. 61
21075588 2011
309
[Varicella-associated purpura fulminans and deep vein thrombosis: a pediatric case report]. 61
21616651 2011
310
[A case of purpura fulminans caused by sepsis with Streptococcus pneumoniae]. 61
21702155 2011
311
Empiric treatment of protracted idiopathic purpura fulminans in an infant: a case report and review of the literature. 61
21605440 2011
312
Protein C deficiency: a case review. 61
21576049 2011
313
Long-term subcutaneous protein C replacement in neonatal severe protein C deficiency. 61
21482600 2011
314
Fatal group A Streptococcus purpura fulminans in a child receiving TNF-α blocker. 61
21063727 2011
315
Reversible blindness: severe pneumococcal induced uveitis following septicaemia. 61
22696694 2011
316
Idiopathic purpura fulminans. 61
20674230 2011
317
Adult purpura fulminans associated with non-steroidal anti-inflammatory drug use. 61
21654144 2011
318
Surgical management of acute infectious purpura fulminans. 61
21233723 2011
319
Use of acellular dermal replacement in reconstruction of nonhealing lower extremity wounds. 61
21131847 2011
320
Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain. 61
21059660 2011
321
Chickenpox is not always benign: postvaricella purpura fulminans requires prompt and aggressive treatment. 61
21131808 2010
322
Neonatal purpura fulminans secondary to group B streptococcal infection. 61
20795772 2010
323
Different faces of leukemia cutis: presenting as purpura fulminans and lupus like butterfly rash. 61
21079325 2010
324
Meningococcal purpura fulminans in children: I. Initial orthopedic management. 61
21966303 2010
325
Meningococcal purpura fulminans in children. II: Late orthopedic sequelae management. 61
21966304 2010
326
Purpura fulminans: a rare presentation of a common disease. 61
20688972 2010
327
Postinfectious purpura fulminans secondary to varicella-induced protein S deficiency. 61
20520582 2010
328
Novel management of post varicella purpura fulminans owing to severe acquired protein S deficiency. 61
20625278 2010
329
Community outbreak of group B meningococcal disease in southwest France--December 2008 to September 2009. 61
20929645 2010
330
Orthopaedic sequelae of childhood meningococcemia: management considerations and outcome. 61
20844162 2010
331
Human skin allografts as a useful adjunct in the treatment of purpura fulminans. 61
20852508 2010
332
Postvaricella purpura fulminans with no evidence of disseminated intravascular coagulation (DIC) or protein S deficiency. 61
21404754 2010
333
Protein C (PROC) gene mutations in two Indian families with purpura fulminans. 61
20077116 2010
334
[Purpura fulminans]. 61
20615377 2010
335
Purpura fulminans in a newborn infant with galactosemia. 61
20016915 2010
336
Case report: perioperative use of protein c concentrate for protein C deficiency in THA. 61
20012238 2010
337
Use of protein C concentrate in neonatal period. 61
21089715 2010
338
Cerebral palsy in siblings caused by compound heterozygous mutations in the gene encoding protein C. 61
20187890 2010
339
Purpura fulminans in meningococcal septicaemia in an adult: a case report. 61
21991197 2010
340
Use of human protein C concentrates in the treatment of patients with severe congenital protein C deficiency. 61
20376174 2010
341
Conservative surgical management of necrotic tissues following meningococcal sepsis: case report of a child treated with hyperbaric oxygen. 61
20462141 2010
342
Symmetrical peripheral gangrene: a prospective study of 14 consecutive cases in a tertiary-care hospital in eastern India. 61
19522719 2010
343
Human protein C concentrate in the treatment of purpura fulminans: a retrospective analysis of safety and outcome in 94 pediatric patients. 61
20723255 2010
344
The purple digit: an algorithmic approach to diagnosis. 61
20141231 2010
345
Persistent Fetal Vasculature and Severe Protein C Deficiency. 61
21045961 2010
346
Secreted virulence factor comparison between methicillin-resistant and methicillin-sensitive Staphylococcus aureus, and its relevance to atopic dermatitis. 61
20109735 2010
347
Clinical images: Purpura fulminans caused by meningococcemia. 61
19858241 2010
348
Severe purpura fulminans due to coexistence of homozygous protein C deficiency and homozygous methylenetetrahydrofolate reductase mutation. 61
19954370 2009
349
[Purpura fulminans (symmetric peripheral gangrene): 7-year consecutive case review in Japan]. 61
20034317 2009
350
Purpura fulminans in a patient with rheumatoid arthritis. 61
19997707 2009
351
Thrombosis associated with varicella zoster in an adult. 61
19398362 2009
352
Application of the vacuum-assisted closure in pediatric patients with orthopedic sequelae of meningococcemia: report of a case successfully treated. 61
19620896 2009
353
Response to the meningococcal meningitis epidemic (MME) at Aminu Kano Teaching Hospital, Kano (2008-2009). 61
20120153 2009
354
Invasive pediatric Neisseria meningitidis infections. 61
20182673 2009
355
Enterocutaneous fistula secondary to purpura fulminans in a preterm infant. 61
19734803 2009
356
Unusual location of purpura fulminans associated with acquired protein C deficiency and administration of propylthiouracil. 61
19747314 2009
357
Pneumococcal sepsis presenting as purpura fulminans in a healthy infant. 61
19689868 2009
358
Purpura fulminans as the presenting manifestation in a patient with juvenile SLE. 61
19950848 2009
359
Nonbacterial purpura fulminans and severe autoimmune acquired protein S deficiency associated with human herpesvirus-6 active replication. 61
19545295 2009
360
Varicella-associated purpura fulminans and multiple deep vein thromboses: a case report. 61
19602824 2009
361
In vivo and in vitro detection of a superantigenic toxin Vbeta signature in two forms of streptococcal toxic shock syndrome. 61
19020908 2009
362
Guidelines for the diagnosis and management of disseminated intravascular coagulation. British Committee for Standards in Haematology. 61
19222477 2009
363
Inpatient rehabilitation of survivors of purpura fulminans with multiple limb amputations: a case series. 61
19345788 2009
364
[Post-varicella purpura fulminans: potentially fatal]. 61
19268637 2009
365
Medical image. A fulminant rash: purpura fulminans. 61
19448795 2009
366
Spot diagnosis: An ominous rash in a newborn. 61
19490602 2009
367
Long-term survival of a child with homozygous protein C deficiency successfully treated with living donor liver transplantation. 61
18482214 2009
368
Purpura fulminans secondary to respiratory infection. 61
19371235 2009
369
Purpura fulminans: a cutaneous marker of disseminated intravascular coagulation. 61
19561767 2009
370
[Purpura fulminans, cerebral infarcts and multiorganic dysfunction due to hantavirus infection. Review and case report]. 61
19350147 2009
371
[Congenital asplenia and pneumococcal purpura fulminans in a pediatric patient: case report with pathological findings and review]. 61
19350161 2009
372
Images in clinical medicine. Purpura fulminans in pneumoccocal sepsis. 61
19787319 2009
373
Spectrum of purpura fulminans. 61
19391008 2009
374
[Meningococcal purpura fulminans]. 61
19177877 2008
375
Purpura fulminans skin loss: surgical management protocols at a regional burns centre. 61
17825634 2008
376
[Spontaneous subdural hematoma associated to purpura fulminans in a splenectomized patient]. 61
19080869 2008
377
Protein C deficiency. 61
19141162 2008
378
Purpura fulminans due to imported falciparum malaria. 61
18607567 2008
379
[Purpura fulminans: a rare complication of chickenpox]. 61
19055261 2008
380
Pediatric critical care management of septic shock prior to acute kidney injury and renal replacement therapy. 61
18790364 2008
381
Rare presentation of a common disease of tropics. 61
19086363 2008
382
A neonate with homozygous protein C deficiency with a homozygous Arg178Trp mutation. 61
18799939 2008
383
Necrotizing haemorrhagic pneumonia proves fatal in an immunocompetent child due to Panton-Valentine Leucocidin, toxic shock syndrome toxins 1 and 2 and enterotoxin C-producing Staphylococcus aureus. 61
18532937 2008
384
Severe congenital protein C deficiency: the use of protein C concentrates (human) as replacement therapy for life-threatening blood-clotting complications. 61
19707361 2008
385
Human protein C concentrates for replacement therapy in congenital and acquired protein C deficiency. 61
18596997 2008
386
Purpura fulminans in a complicated Falciparum malaria. 61
18822630 2008
387
[Rare thrombophilic states]. 61
18394759 2008
388
[A 52-year-old woman with acute shock and purpura fulminans. Pneumococcal sepsis]. 61
18322667 2008
389
Purpura fulminans in systemic lupus erythematosus. 61
18380706 2008
390
Purpura fulminans secondary to Streptococcus pneumoniae sepsis: unraveling the pattern of cytokines. 61
18328292 2008
391
Purpura fulminans: a case series managed at a regional burn center. 61
18354305 2008
392
Occult methicillin-resistant Staphylococcus aureus abscesses in 2 pediatric patients. 61
17873245 2008
393
Severe congenital protein C deficiency: description of a new mutation and prophylactic protein C therapy and in vivo pharmacokinetics. 61
18376272 2008
394
The use of artificial dermis (Integra) and topical negative pressure to achieve limb salvage following soft-tissue loss caused by meningococcal septicaemia. 61
18078796 2008
395
Hypothesis: is the skin and tissue loss associated with septic purpura fulminans temperature related? Parallels with the anatomical distribution of frostbite. 61
18221840 2008
396
A devastating case of purpura fulminans in a young adult seven years after a splenectomy: a case report. 61
18341162 2008
397
Presentation and outcome of purpura fulminans associated with peripheral gangrene in 12 patients at Mayo Clinic. 61
17719676 2007
398
Severe complications of chickenpox in hospitalised children in the UK and Ireland. 61
17991685 2007
399
Case of purpura fulminans due to septicemia after artificial abortion. 61
17973822 2007
400
Severe spotted fever group rickettsiosis, Australia. 61
18217560 2007
401
Meningococcal septicaemia complications involving skin and underlying deeper tissues--management considerations and outcome. 61
18069582 2007
402
A history of adjunctive glucocorticoid treatment for pediatric sepsis: moving beyond steroid pulp fiction toward evidence-based medicine. 61
17914311 2007
403
[Waterhouse-Friderichsen syndrome associated to a Morganella morganii and Enterococcus faecium peritonitis]. 61
17766079 2007
404
Severe myalgia of the lower extremities as the first clinical feature of meningococcal purpura fulminans. 61
17978078 2007
405
[Meningococcal purpura fulminans: treatment with recombinant protein C activator in 3 cases]. 61
17993100 2007
406
Purpura fulminans: an unusual manifestation of severe falciparum malaria. 61
17588627 2007
407
Purpura fulminans in a child secondary to Panton-Valentine leukocidin-producing Staphylococcus aureus. 61
17893182 2007
408
Purpura fulminans in an asplenic patient. 61
17897291 2007
409
Idiopathic purpura fulminans in dengue hemorrhagic fever. 61
17679737 2007
410
Bilateral leukocoria in a patient with homozygous protein C deficiency. 61
17603727 2007
411
Activated protein C. 61
17635713 2007
412
Purpura fulminans without meningitis: a rare condition? 61
17602916 2007
413
Detection of Neisseria meningitidis DNA from skin lesion biopsy using real-time PCR: usefulness in the aetiological diagnosis of purpura fulminans. 61
17503017 2007
414
Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T-cell receptor Vbeta8.2. 61
17427250 2007
415
Antiphospholipid antibodies in Turkish children with thrombosis. 61
17473576 2007
416
[Septic shock with purpura fulminans after a dog bite]. 61
17551886 2007
417
Purpura fulminans in paroxysmal nocturnal haemoglobinuria. 61
17456051 2007
418
[Management of purpura fulminans apropos of 21 cases: diagnostic delay and therapeutic problems]. 61
17657920 2007
419
Safety and usefulness of invasive arterial blood pressure monitoring in purpura fulminans resuscitation. 61
17392648 2007
420
[Saved case of purpura fulminans in pneumococcal sepsis after splenectomy]. 61
17506318 2007
421
The cytoprotective protein C pathway. 61
17110453 2007
422
What may underlie recurrent purpura fulminans? 61
17407438 2007
423
Cutaneous manifestations in renal failure patients: a case series. 61
17456917 2007
424
[Purpura fulminans due to pneumococcal pneumonia in a healthy adult: a case report]. 61
17447479 2007
425
Capnocytophaga ochracea causing severe sepsis and purpura fulminans in an immunocompetent patient. 61
16882454 2007
426
Cutaneous pseudovasculitis. 61
17284961 2007
427
Purpura fulminans associated with Lactobacillus paracasei liver abscess. 61
17323680 2007
428
Molecular analysis of staphylococcal superantigens. 61
18025673 2007
429
Successful treatment of septic shock with purpura fulminans caused by Trichosporon asahii in an immunocompetent patient. 61
18000295 2007
430
Negative pressure dressing for promoting wound healing of purpura fulminans in a newborn with homozygous protein C deficiency. 61
17179832 2007
431
Recurrent vasculopathic skin lesions associated with homozygous protein C deficiency. 61
17300652 2007
432
Purpura fulminans in sepsis. 61
17170624 2006
433
Meningococcal purpura fulminans treated with medicinal leeches. 61
16878049 2006
434
Nonpalpable purpura within a setting of anticoagulant therapy and metastatic carcinoma. 61
16928675 2006
435
Suitable age for nasal reconstruction after subtotal amputation in a child, with respect to a case involving purpura fulminans. 61
16952604 2006
436
Salvaging limbs in cases of severe purpura fulminans: advantages of free flaps. 61
16932177 2006
437
Purpura fulminans secondary to transient protein C deficiency as a complication of chickenpox infection. 61
16918648 2006
438
Prolonged outbreak of B meningococcal disease in the Seine-Maritime department, France, January 2003 to June 2005. 61
29208111 2006
439
Prolonged outbreak of B meningococcal disease in the Seine-Maritime department, France, January 2003 to June 2005. 61
16966800 2006
440
Neonatal thromboembolic emergencies. 61
16520103 2006
441
Purpura fulminans due to Stenotrophomonas maltophilia infection in a premature infant. 61
16732810 2006
442
Management of neonatal purpura fulminans with severe protein C deficiency. 61
16820665 2006
443
[Management of chicken pox purpura fulminans: a pediatric case report]. 61
16504361 2006
444
Hyperbaric oxygen therapy for purpura fulminans-comment. 61
16714977 2006
445
Treatment of adult patients with sepsis-induced coagulopathy and purpura fulminans using a plasma-derived protein C concentrate (Ceprotin). 61
16635072 2006
446
Severe type I protein C deficiency with neonatal purpura fulminans due to a novel homozygous mutation in exon 6 of the protein C gene. 61
16689776 2006
447
Purpura fulminans during meningococcal sepsis treated with Drotrecogin alpha. A clinical case. 61
16570037 2006
448
[Surgical management of cutaneous and musculoskeletal complications in fulminant sepsis]. 61
16846126 2006
449
[Invasive infections caused by Haemophilus influenzae type b after the institution of the conjugated vaccine on the expanded programm on immunization in Chile]. 61
16462964 2006
450
[Vascular emergencies in dermatology]. 61
16496102 2006
451
Fatal illness associated with pulmonary hypertension in a neonate caused by intrauterine echovirus 11 infection. 61
16450275 2006
452
Varicella-associated purpura fulminans: chicken pox is not always benign. 61
16651842 2006
453
Pneumococcal septicaemia with Purpura fulminans in an 11-month-old child. 61
17113523 2006
454
Purpura fulminans in an adult patient with Haemophilus influenzae sepsis: case report and review of the literature. 61
16566545 2006
455
Serratia marcescens septicemia presenting as purpura fulminans in a premature newborn. 61
16331334 2005
456
[Spontaneous skin necrosis from acquired protein S deficiency in a renal transplant recipient]. 61
16374391 2005
457
Epidemiology of invasive meningococcal disease in France in 2003. 61
29208146 2005
458
Epidemiology of invasive meningococcal disease in France in 2003. 61
16371693 2005
459
Clinico-pathologic conference: an 11-year-old girl with lupus erythematosus, venous thromboses, and purpura fulminans. 61
16761561 2005
460
Outcome in children with purpura fulminans: report on 16 patients. 61
16138355 2005
461
Purpura fulminans as a sequel to erythema nodosum in a child with homozygous Leiden mutation and acquired protein S deficiency. 61
16188867 2005
462
Drotrecogin alfa (activated) in patients with severe sepsis presenting with purpura fulminans, meningitis, or meningococcal disease: a retrospective analysis of patients enrolled in recent clinical studies. 61
16137345 2005
463
Hyperbaric oxygen therapy for purpura fulminans: comment. 61
16027587 2005
464
[Purpura fulminans: what do hormonal and haemostatic treatments add?]. 61
15904794 2005
465
Soft-tissue reconstruction after meningococcal septicemia using a posterior tibial artery perforator flap in a 6-year-old boy. 61
15883822 2005
466
Anti-protein S antibodies following a varicella infection: detection, characterization and influence on thrombin generation. 61
15946215 2005
467
Interest of postmortem-collected specimens in the diagnosis of fulminant meningococcal sepsis. 61
15878445 2005
468
Disseminated necrosis of the breast associated with purpura fulminans. 61
15871715 2005
469
Staphylococcal purpura fulminans: a toxin-mediated disease? 61
15824984 2005
470
Purpura fulminans -- soft tissue damage as a manifestation of bacterial sepsis. 61
15877261 2005
471
[The serratus anterior free flap in limb reconstruction. About 30 cases]. 61
15695013 2005
472
Neisseria meningitidis C:2b:P1.2,5 with decreased susceptibility to penicillin isolated from a patient with meningitis and purpura fulminans. 61
15685394 2005
473
Purpura fulminans successfully treated with hyperbaric oxygen--a report of 2 cases. 61
15643321 2005
474
Vibrio vulnificus septicemia presenting as purpura fulminans. 61
15841662 2005
475
Plastic surgery management in pediatric meningococcal-induced purpura fulminans. 61
15636769 2005
476
Energy expenditure and gait characteristics of a bilateral amputee walking with C-leg prostheses compared with stubby and conventional articulating prostheses. 61
15468036 2004
477
Coagulation in sepsis. 61
15486534 2004
478
Use of recombinant tissue plasminogen activator in children with meningococcal purpura fulminans: a retrospective study. 61
15286558 2004
479
Recombinant tissue plasminogen activator in children with meningococcal purpura fulminans--role uncertain. 61
15286574 2004
480
Pneumococcal-associated purpura fulminans in a healthy infant. 61
15295249 2004
481
Purpura fulminans -- a novel presentation of Churg Strauss syndrome. 61
15245538 2004
482
Purpura fulminans due to Enterococcus faecalis. 61
15645965 2004
483
Clinical and laboratory evaluation of Turkish children with thrombosis for homozygous factor V G1691A mutation. 61
15166921 2004
484
Meningococcal purpura fulminans in a patient with systemic lupus erythematosus: a mimic for catastrophic antiphospholipid antibody syndrome? 61
15201656 2004
485
[Postvaricella purpura fulminans]. 61
15207173 2004
486
Capnocytophaga canimorsus sepsis with purpura fulminans and symmetrical gangrene following a dog bite in a shelter employee. 61
15201655 2004
487
Protein C/activated protein C pathway: overview of clinical trial results in severe sepsis. 61
15118517 2004
488
[Use of protein C concentrate in critical conditions: clinical experience in pediatric patients with sepsis]. 61
15181416 2004
489
[Meningococcal purpura fulminans in children]. 61
15296272 2004
490
[Septic shock with purpura fulminans due to Capnocytophaga canimorsus]. 61
15207129 2004
491
Historical Article: Hirudo medicinalis: ancient origins of, and trends in the use of medicinal leeches throughout history. 61
15013545 2004
492
An idiopathic skin eruption resembling a butterfly rash in a septic patient with disseminated intravascular coagulation following bone marrow transplantation. 61
15060423 2004
493
Disseminated intravascular coagulation and coagulation disorders. 61
17021539 2004
494
Circulating aldosterone levels are unexpectedly low in children with acute meningococcal disease. 61
15001642 2004
495
Coagulopathy of sepsis. 61
14961146 2004
496
Fulminant meningococcemia and acute renal failure in a 3-year-old boy. 61
14648332 2004
497
Purpura fulminans due to E. coli septicemia. 61
15008315 2004
498
Diagnosis and treatment of a newborn with homozygous protein C deficiency. 61
14989454 2004
499
Purpura fulminans in a child as a complication of chickenpox infection. 61
15118384 2004
500
Replacement treatment with protein C in an 18-year-old man with meningococcal sepsis and purpura fulminans. 61
14564239 2003
501
The protein C pathway. 61
12970121 2003
502
[Surgical management of cutaneous necrosis in the purpura fulminans: report of 2 clinical cases]. 61
12927881 2003
503
Pathophysiology of meningococcal meningitis and septicaemia. 61
12818907 2003
504
Chronic lymphocytic leukemia presenting as purpura fulminans. 61
12857575 2003
505
Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding study. 61
12794428 2003
506
Current management of purpura fulminans: a multicenter study. 61
12792230 2003
507
Purpura fulminans associated with Capnocytophaga canimorsus infection. 61
12670324 2003
508
[Streptococcus suis bacteremia]. 61
12714914 2003
509
[Meningococcal purpura fulminans]. 61
12735301 2003
510
Homozygous protein C deficiency with purpura fulminans: report of a new case and a description of a novel mutation. 61
12695756 2003
511
Surgical interventions in children with meningococcal purpura fulminans--a review of 117 procedures in 21 children. 61
12677574 2003
512
Idiopathic purpura fulminans and varicella gangrenosa of both hands, toes and integument in a child. 61
12791376 2003
513
Tissue-engineered skin in the healing of wound stumps from limb amputations secondary to purpura fulminans. 61
12657020 2003
514
Purpura fulminans. 61
12709001 2003
515
Purpura fulminans. 61
12573375 2003
516
Drotrecogin alfa (activated) for the treatment of meningococcal purpura fulminans. 61
12594601 2003
517
First manifestation of a hereditary homozygous factor VII deficiency in a 3-year-old girl suspected as purpura fulminans. 61
12528040 2003
518
Adult purpura fulminans associated with staphylococcal infection and administration of colony-stimulating factors. 61
12609794 2003
519
An unusual varicella zoster infection complicated by purpura fulminans and multiorgan failure in a healthy infant. 61
12685891 2003
520
Acute infectious purpura fulminans: a 15-year retrospective review of 28 consecutive cases. 61
12575789 2003
521
A case report of purpura fulminans secondary to transient protein C deficiency as a complication of chickenpox infection. 61
12718382 2003
522
Chronic disseminated intravascular coagulation and childhood-onset skin necrosis resulting from homozygosity for a protein C Gla domain mutation, Arg15Trp. 61
12439046 2002
523
Acute infectious purpura fulminans associated with asplenism or hyposplenism. 61
12271289 2002
524
PAI-1 gene 4G/5G genotype: A risk factor for thrombosis in vessels of internal organs. 61
12353306 2002
525
Analysis of pathogen-host cell interactions in purpura fulminans: expression of capsule, type IV pili, and PorA by Neisseria meningitidis in vivo. 61
12183570 2002
526
Successful treatment of fulminant pneumococcal sepsis with recombinant tissue plasminogen activator. 61
12225785 2002
527
Multivisceral transplantation for portal hypertension and diffuse mesenteric thrombosis caused by protein C deficiency. 61
12177622 2002
528
[Purpura fulminans. A fatal consequence of a widely used medication?]. 61
12219272 2002
529
Klebsiella-induced purpura fulminans in a Nigerian child: case report and a review of literature. 61
12744583 2002
530
Postvaricella purpura fulminans caused by acquired protein s deficiency resulting from antiprotein s antibodies: search for the epitopes. 61
12142795 2002
531
Report of eight infants with acute infantile hemorrhagic edema and review of the literature. 61
12081160 2002
532
Vaccination campaign following an increase in incidence of serogroup C meningococcal diseases in the department of Puy-de-Dôme (France). 61
12631934 2002
533
Necrotizing fasciitis and purpura fulminans. 61
11994643 2002
534
A case of purpura fulminans secondary to transient protein C deficiency as a complication of chickenpox infection. 61
12026205 2002
535
Spontaneous orbital haemorrhage in purpura fulminans secondary to meningococcal septicaemia. 61
11988822 2002
536
Human recombinant activated protein C in meningococcal sepsis. 61
11796469 2002
537
Purpura fulminans and anticardiolipin antibodies in a patient with Grave's disease. 61
12492254 2002
538
Sequential microsurgical flap reconstruction following purpura fulminans during infancy and childhood. 61
11917951 2002
539
Recurrent purpura fulminans associated with drug-resistant Streptococcus pneumoniae infection in an asplenic girl. 61
11791110 2002
540
[Perioperative management of a patient with purpura fulminans syndrome due to protein C deficiency]. 61
11744581 2001
541
Ulcerative colitis presenting as purpura fulminans. 61
11720322 2001
542
[Bacterial meningitis and purpura fulminans in the child]. 61
11787221 2001
543
[Purpura fulminans and coxsackie B2 co-infection]. 61
11732467 2001
544
[Idiopathic purpura fulminans with transient protein S deficiency]. 61
11578547 2001
545
Neonatal purpura fulminans due to homozygous protein C deficiency. 61
11594708 2001
546
Management of purpura fulminans. 61
11878745 2001
547
[Meningococcal W135 infection epidemics associated with pilgrimage to Mecca in 2000]. 61
11721491 2001
548
[Development of intensive care for pediatric infectious diseases over the last 20 years]. 61
11582911 2001
549
[Pediatric deaths due to community-acquired bacterial infection. Survey of French pediatric intensive care units]. 61
11582916 2001
550
The varicella-autoantibody syndrome. 61
11518821 2001
551
[Treatment of meningococcal purpura fulminans]. 61
11582913 2001
552
Invasive pneumococcal infection and drug-resistant Streptococcus pneumoniae in Thai children. 61
11800296 2001
553
[Epidemiology of purpura fulminans and early therapeutic recommendations]. 61
11582912 2001
554
[Meningococcal purpura fulminans: untoward result of genetic polymorphism?]. 61
11524916 2001
555
Dysfunction of endothelial protein C activation in severe meningococcal sepsis. 61
11496851 2001
556
Protein C anticoagulant pathway and its role in controlling microvascular thrombosis and inflammation. 61
11445734 2001
557
Invasive serotype a Haemophilus influenzae infections with a virulence genotype resembling Haemophilus influenzae type b: emerging pathogen in the vaccine era? 61
11433097 2001
558
Myocardial injury in meningococcus-induced purpura fulminans in children. 61
11497141 2001
559
Use of tissue expansion in revision of unhealed below-knee amputation stumps. 61
11484529 2001
560
Protein C replacement in severe meningococcemia: rationale and clinical experience. 61
11303270 2001
561
Thromboembolic complications in Thai pediatric patients. 61
11560218 2001
562
The protective effect of brachial plexus palsy in purpura fulminans. 61
11516614 2001
563
Free-tissue transfer for limb salvage in Purpura fulminans. 61
11335814 2001
564
Review of management of purpura fulminans and two case reports. 61
11573639 2001
565
Massive infectious soft-tissue injury: diagnosis and management of necrotizing fasciitis and purpura fulminans. 61
11252099 2001
566
Clinical management of protein C deficiency. 61
11336597 2001
567
Sepsis-associated purpura fulminans in adults. 61
11253735 2001
568
Thrombolytic therapy in children--clinical experiences with recombinant tissue-plasminogen activator. 61
11372772 2001
569
Streptococcal toxic shock syndrome revealed by a peritonitis. Case report and review of the literature. 61
11234313 2001
570
Purpura fulminans in a patient with malaria. 61
11125325 2000
571
Fulminant purpuric rash. 61
11764144 2000
572
Management of purpura fulminans at the upper extremity. 61
11117060 2000
573
Purpura fulminans caused by group A beta-hemolytic Streptococcus sepsis. 61
11035839 2000
574
Anticoagulant proteins in childhood venous and arterial thrombosis: a review. 61
11112387 2000
575
[Pain therapy in acute pediatric diseases and vaccination]. 61
12800021 2000
576
[Meningococcal meningitis in the adult complicated by cutaneous necrosis: description of a clinical case]. 61
11202631 2000
577
Lupus anticoagulant and protein S deficiency in otherwise healthy children with acute varicella infection. 61
11083373 2000
578
Recombinant bactericidal/permeability-increasing protein (rBPI21) as adjunctive treatment for children with severe meningococcal sepsis: a randomised trial. rBPI21 Meningococcal Sepsis Study Group. 61
11041396 2000
579
Do new strategies in meningococcemia produce better outcomes? 61
11007200 2000
580
Purpura fulminans in the early postnatal period in a woman with protein C deficiency. 61
15512647 2000
581
Neonatal purpura fulminans due to protein C deficiency. 61
11192996 2000
582
Aggressive multiple modality therapy for varicella-associated purpura fulminans. 61
11202910 2000
583
[Streptococcus A meningitis revealed by purpura fulminans]. 61
11039087 2000
584
Antithrombin concentrate with plasma exchange in purpura fulminans. 61
12813293 2000
585
Protein C substitution in sepsis-associated purpura fulminans. 61
10921567 2000
586
Disseminated intravascular coagulation and purpura fulminans secondary to infection. 61
10942620 2000
587
Validation of a diagnosis model for differentiating bacterial from viral meningitis in infants and children under 3.5 years of age. 61
10947215 2000
588
The use of simultaneous free latissimus dorsi tissue transfers for reconstruction of bilateral upper extremities in a case of purpura fulminans. 61
10811762 2000
589
Massive subperiosteal hemorrhage and femoral shaft osteonecrosis: a complication of tissue plasminogen activator therapy for purpura fulminans. 61
10784021 2000
590
[Alpha-hemolytic streptococci as a cause of purpura fulminans]. 61
10846661 2000
591
Non-Q wave acute myocardial infarction in acute meningococcemia in a 10-year-old girl. 61
10698142 2000
592
Severe protein C deficiency and aseptic osteonecrosis of the hip joint: a case report. 61
10650859 1999
593
Thrombolytic therapy in adult meningococcal purpura fulminans with acute renal failure and severe perfusion deficits to the extremities. 61
10510843 1999
594
Necrotizing vasculitis secondary to propylthiouracil presenting as purpura fulminans. 61
10501437 1999
595
Infectious purpura fulminans: caution needed in the use of protein c 61
10444324 1999
596
Infectious purpura fulminans: caution needed in the use of protein C. 61
10444197 1999
597
Long-term management of homozygous protein C deficiency: replacement therapy with subcutaneous purified protein C concentrate. 61
10404762 1999
598
Purpura fulminans associated with Streptococcus pneumoniae infection in a child. 61
10389955 1999
599
Ophthalmic manifestation of congenital protein C deficiency. 61
10428594 1999
600
Confluent ecchymoses on the lower extremities of a malnourished patient. 61
10405489 1999
601
Topical nitroglycerin and pain in purpura fulminans. 61
10228302 1999
602
[Multiple amputations due to sepsis: however, functional rehabilitation is possible]. 61
10368740 1999
603
Clinical manifestations in thrombotic children with factor V Leiden mutation. 61
10326221 1999
604
[Meningococcal sepsis in 3 young men]. 61
10230384 1999
605
Reconstructive surgery in children after meningococcal purpura fulminans. 61
10235331 1999
606
[Purpura fulminans as complication of Mycoplasma pneumoniae infection]. 61
10207854 1999
607
Purpura fulminans in children: report of two cases. 61
10910600 1999
608
Infectious purpura fulminans: diagnosis and treatment. 61
10050699 1999
609
Purpura fulminans complicating pneumococcal sepsis. 61
10048620 1999
610
Compound heterozygosity for one novel and one recurrent mutation in a Thai patient with severe protein S deficiency. 61
10063989 1999
611
Analysis of the protein s gene in protein s deficiency. 61
21341001 1999
612
Severe panarteritis associated with drug abuse. 61
10051089 1999
613
Replacement therapy with protein C concentrate in infants and adolescents with meningococcal sepsis and purpura fulminans. 61
10632475 1999
614
Hyperbaric oxygen therapy in the pediatric patient: the experience of the Israel Naval Medical Institute. 61
9794983 1998
615
Purpura fulminans localising to a recent burn injury. 61
9882071 1998
616
[Where are we with purpura fulminans?]. 61
9809147 1998
617
[Post-chickenpox purpura fulminans with transient reduction of C and S proteins]. 61
9859560 1998
618
[Homozygous protein C deficiency can be detected by prenatal diagnosis]. 61
9766136 1998
619
Chilblains and Raynaud phenomenon are usually not a sign of hereditary protein C and S deficiencies. 61
9779252 1998
620
Molecular and genetic analysis of iron uptake proteins in the brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius. 61
9727086 1998
621
Rupert Waterhouse and Carl Friderichsen: adrenal apoplexy. 61
9696186 1998
622
Neurovascularized saphenous island flap in a patient with meningococcal sepsis and purpura fulminans. 61
9678482 1998
623
Integra Artificial Skin as a useful adjunct in the treatment of purpura fulminans. 61
9710731 1998
624
Preamputation MR imaging in meningococcemia and comparison to conventional arteriography. 61
9634456 1998
625
Therapeutic levels of human protein C in rats after retroviral vector-mediated hepatic gene therapy. 61
9637717 1998
626
Homozygous protein C deficiency with a double variant His 202 to Tyr and Ala 346 to Thr. 61
9690806 1998
627
Protein C in the treatment of coagulopathy in meningococcal disease. 61
9590329 1998
628
Surgical treatment of extensive skin necrosis secondary to purpura fulminans in a patient with meningococcal sepsis. 61
9677033 1998
629
Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura fulminans. 61
9590330 1998
630
Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura fulminans. 61
9590331 1998
631
Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura fulminans. 61
9590332 1998
632
Acute infectious purpura fulminans: pathogenesis and medical management. 61
9655311 1998
633
Neonatal purpura fulminans due to homozygous protein C deficiency. 61
9604607 1998
634
Purpura fulminans: a disease best managed in a burn center. 61
9556312 1998
635
Protein-C concentrate for meningococcal purpura fulminans. 61
9734967 1998
636
Protein-C concentrate for meningococcal purpura fulminans. 61
9734968 1998
637
Protein-C concentrate for meningococcal purpura fulminans. 61
9734969 1998
638
Protein-C concentrate for meningococcal purpura fulminans. 61
9734970 1998
639
Purpura fulminans skin lesions in a newborn with complete protein C deficiency. 61
9544924 1998
640
Spontaneous tibial artery thrombosis associated with varicella pneumonia and free protein S deficiency. 61
9546247 1998
641
Compared contralateral application of topical nitroglycerin on purpura fulminans. 61
9505568 1998
642
[Recombinant tissue plasminogen activator in treatment of fulminant meningococcal infection]. 61
9445924 1997
643
Severe skin loss after meningococcal septicaemia: complications in treatment. 61
9401526 1997
644
Use of protein-C concentrate, heparin, and haemodiafiltration in meningococcus-induced purpura fulminans. 61
9393338 1997
645
Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura fulminans. 61
9201041 1997
646
Recombinant tissue plasminogen activator restores perfusion in meningococcal purpura fulminans. 61
9201064 1997
647
Streptococcus suis infection complicated by purpura fulminans and rhabdomyolysis: case report and review. 61
9145747 1997
648
APC resistance in childhood thromboembolism: diagnosis and clinical aspects. 61
9255906 1997
649
Purpura fulminans in pneumococcal sepsis: case report and review. 61
9435036 1997
650
Necrotizing group A streptococcal infections associated with streptococcal toxic shock syndrome. 61
8942557 1996
651
Severe acquired neonatal purpura fulminans. 61
8829009 1996
652
[Purpura fulminans with extensive skin necroses]. 61
8926172 1996
653
Images in clinical medicine. Purpura fulminans in Neisseria meningitidis sepsis. 61
8637516 1996
654
[Use of tissue expansion on defective amputation stumps of the lower limbs. Apropos of 5 cases]. 61
8761060 1996
655
[Definitions of sepsis in severe juvenile meningococcal infection. A review of 80 cases]. 61
8830594 1996
656
Pedal manifestations of meningococcal septicemia. 61
8775175 1996
657
Lupus anticoagulant and protein S deficiency in children with postvaricella purpura fulminans or thrombosis. 61
8774497 1996
658
Purpura fulminans in a patient homozygous for a mutation in the protein C gene--prenatal diagnosis in a subsequent pregnancy. 61
8701425 1996
659
Management strategy in purpura fulminans with multiple organ failure in children. 61
8719318 1996
660
[Disseminated intravascular coagulations]. 61
9005011 1996
661
Purpura fulminans in severe congenital protein C deficiency: monitoring of treatment with protein C concentrate. 61
8750805 1996
662
Severe type I protein C deficiency in a compound heterozygote for Y124C and Q132X mutations in exon 6 of the PROC gene. 61
8607097 1995
663
Postinfectious purpura fulminans caused by an autoantibody directed against protein S. 61
7658262 1995
664
Successful use of leeches in the treatment of purpura fulminans. 61
7503526 1995
665
Hyperkalemic cardiac arrest after succinylcholine administration in a child with purpura fulminans. 61
7605002 1995
666
Homozygous protein C deficiency--management with protein C concentrate. 61
7556318 1995
667
Causes of purpura fulminans. 61
7667065 1995
668
Treatment of purpura fulminans in meningococcemia with protein C concentrate. 61
7699550 1995
669
Varicella (purpura fulminans variant) in an adult diagnosed at autopsy. 61
7546024 1995
670
Severe autoimmune protein S deficiency in a boy with idiopathic purpura fulminans. 61
7734361 1995
671
Warfarin-induced necrosis of the skin. 61
7741443 1995
672
The burn unit as a resource for the management of acute nonburn conditions in children. 61
7721912 1995
673
Replacement therapy with a monoclonal antibody purified protein C concentrate in newborns with severe congenital protein C deficiency. 61
8747700 1995
674
Coagulation activation and tissue necrosis in meningococcal septic shock: severely reduced protein C levels predict a high mortality. 61
7740486 1995
675
The role of heparin in the prevention of extremity and digit necrosis in meningococcal purpura fulminans. 61
7854884 1994
676
[Purpura fulminans complicating pneumococcal sepsis: a case report]. 61
7963803 1994
677
Varicella and thrombotic complications associated with transient protein C and protein S deficiencies in children. 61
7957422 1994
678
Surgical intervention for the complications of meningococcal-induced purpura fulminans. 61
7970975 1994
679
Purpura fulminans following a dog bite. 61
7937460 1994
680
A novel homozygous missense mutation (Val 325-->Ala) in the protein C gene causing neonatal purpura fulminans. 61
7841324 1994
681
Severe homozygous protein C deficiency: identification of a splice site missense mutation (184, Q-->H) in exon 7 of the protein C gene. 61
7974377 1994
682
[Protein S deficiency and thrombophilia: presentation of a clinical case and review of the literature]. 61
7946892 1994
683
Homozygous protein S deficiency due to a one base pair deletion that leads to a stop codon in exon III of the protein S gene. 61
7974339 1994
684
[Fulminant purpura in Still's disease and bacteremia with Xanthomonas maltophilia and coagulase-negative staphylococci]. 61
8016605 1994
685
Desepiphysiodesis--elimination of partial premature epiphyseal closure. Experience of 17 cases. 61
8199130 1994
686
A case of protein C deficiency associated with cerebral infarction and obstruction of deep leg and inferior mesenteric veins. 61
8201799 1993
687
A compound heterozygous protein C deficiency with a single nucleotide G deletion encoding Gly-381 and an amino acid substitution of Lys for Gla-26. 61
8115990 1993
688
Recombinant tissue plasminogen activator for neonatal and pediatric vascular thrombolytic therapy. 61
8263684 1993
689
Acquired purpura fulminans induced by alcohol and acetaminophen. Successful treatment with heparin and vitamin K. 61
8215490 1993
690
Normalization of markers of coagulation activation with a purified protein C concentrate in adults with homozygous protein C deficiency. 61
8353282 1993
691
Nursing care of a child with meningococcemia. 61
8410641 1993
692
Epidemic meningococcemia and purpura fulminans with induced protein C deficiency. 61
8399877 1993
693
Clotting and thrombotic disorders of the skin in children. 61
8374673 1993
694
Epidural sympathetic blockade to relieve vascular insufficiency in an infant with purpura fulminans. 61
8375170 1993
695
Symmetrical peripheral gangrene (purpura fulminans) complicating pneumococcal sepsis. 61
7683845 1993
696
Risk factors for death in meningococcal disease. 61
8327268 1993
697
Severe acquired protein C deficiency in purpura fulminans associated with disseminated intravascular coagulation: treatment with protein C concentrate. 61
8424021 1993
698
Rapid recovery of acquired purpura fulminans in a patient with familial C4bBP deficiency. 61
8486865 1993
699
Thrombotic complications of BMT: association with protein C deficiency. 61
8431711 1993
700
[Alcoholism and severe pneumococcal infection. Apropos of a case of purpura fulminans caused by Streptococcus pneumoniae]. 61
8362110 1993
701
Purpura fulminans secondary to pneumococcal sepsis in an asplenic patient. 61
8419630 1993
702
Streptococcal gangrene and purpura fulminans. 61
1298264 1992
703
Meningococcaemia in an adult with hereditary C4b-binding protein deficiency: study of the variations of the protein S system. 61
1450338 1992
704
Protein C survival during replacement therapy in homozygous protein C deficiency. 61
1503096 1992
705
Meningococcal disease and influenza-like syndrome: a new approach to an old question. 61
1500737 1992
706
Haemophilus influenzae type b purpura fulminans treated with hyperbaric oxygen. 61
1431173 1992
707
Purpura fulminans due to protein S deficiency following chickenpox. 61
1386247 1992
708
Purpura fulminans, metastatic endophthalmitis, and thrombotic thrombocytopenic purpura in an HIV-infected patient. 61
1518589 1992
709
Management of cutaneous manifestations of extensive purpura fulminans in a burn unit. 61
1429811 1992
710
[Purpura fulminans]. 61
1497233 1992
711
Extremity amputations in meningococcemia-induced purpura fulminans. 61
1561259 1992
712
Successful treatment of neonatal purpura fulminans with epoprostenol. 61
1433077 1992
713
[Localized bacterial skin infections and dermatologic manifestations of systemic infections]. 61
1615460 1992
714
Protein S deficiency and skin necrosis associated with continuous ambulatory peritoneal dialysis. 61
1532474 1992
715
[Discovery of IgG subclass deficiency in a case of meningococcal purpura fulminans]. 61
1532095 1992
716
Removal of circulating tumor necrosis factor. Its role in septic shock treatment. 61
1300881 1992
717
Neonatal bone infarction following cord sepsis: case report. 61
1602506 1992
718
Unusual manifestations of pneumococcal infection in human immunodeficiency virus-infected individuals: the past revisited. 61
1571428 1992
719
Treatment of homozygous protein C deficiency and neonatal purpura fulminans with a purified protein C concentrate. 61
1944440 1991
720
Successful treatment of neonatal purpura fulminans with epoprostenol. 61
1744852 1991
721
[Purpura fulminans--aspects of etiopathogenesis, clinical aspects, diagnosis and therapy]. 61
1755239 1991
722
[The significance of protein C deficiency in dermatology]. 61
1757253 1991
723
Purpura fulminans and symmetrical peripheral gangrene caused by Capnocytophaga canimorsus (formerly DF-2) septicemia--a complication of dog bite. 61
1921703 1991
724
Purpura fulminans as clinical manifestation of atypical SLE with antiphospholipid antibodies: a case report. 61
1806449 1991
725
Purpura fulminans in three cases of early-onset neonatal group B streptococcal meningitis. 61
1890473 1991
726
Purpura fulminans and adrenal hemorrhage due to group Y meningococcemia in an elderly woman. 61
1901668 1991
727
Purpura fulminans secondary to Xanthomonas maltophilia sepsis in an adult with aplastic anemia. 61
1918597 1991
728
[Purpura fulminans and C7 deficiency complicated by Pneumocystis carinii pneumonia]. 61
1681768 1991
729
Use of topically applied nitroglycerin in the treatment of purpura fulminans. 61
2123242 1990
730
[Pneumococcal meningoencephalitis associated with purpura fulminans in a non-splenectomized subject]. 61
2149606 1990
731
Homozygous protein S deficiency in an infant with purpura fulminans. 61
2231208 1990
732
Acquired purpura fulminans. 61
2281320 1990
733
Dermatopathology of skin necrosis associated with purpura fulminans. 61
2281318 1990
734
Purpura fulminans of the head and neck. 61
2123330 1990
735
Neonatal purpura fulminans due to homozygous protein C or protein S deficiencies. 61
2149204 1990
736
Proposed classification and pathologic mechanisms of purpura fulminans and skin necrosis. 61
2281322 1990
737
Hereditary protein C deficiency: a review of the genetics, clinical presentation, diagnosis and treatment. 61
2103316 1990
738
[Purpura fulminans]. 61
2244264 1990
739
Ischemic stroke due to protein C deficiency. 61
2195715 1990
740
The surgical implications of purpura fulminans. 61
2340249 1990
741
Neonatal purpura fulminans and transient protein C deficiency. 61
2357107 1990
742
Protein C and protein S levels in two patients with acquired purpura fulminans. 61
2142890 1990
743
Homozygous protein C deficiency in two siblings. 61
2206858 1990
744
Neonatal purpura fulminans associated with homozygous protein S deficiency. 61
1967377 1990
745
More questions about purpura fulminans. 61
2297246 1990
746
A rare association of rhabdomyolysis and purpura fulminans in Strep. pneumoniae septicemia. 61
2286737 1990
747
Purpura fulminans. 61
2299160 1990
748
Salmonella meningitis complicated with subdural empyema, brain abscess and purpura fulminans: report of one case. 61
2576904 1989
749
Purpura fulminans associated with overwhelming sepsis and disseminated intravascular coagulation following splenectomy. 61
2592186 1989
750
Dysgonic fermenter type 2 septicemia with purpura fulminans. Dermatologic features of a zoonosis acquired from household pets. 61
2802646 1989
751
[Neisseria meningitidis: serogroup Y. Apropos of 38 cases]. 61
2515521 1989
752
Neonatal protein C: molecular composition and distribution in normal term infants. 61
2595675 1989
753
Meningococcal purpura fulminans: treatment of vascular insufficiency in a 2-yr-old child with lumbar epidural sympathetic blockade. 61
2774279 1989
754
Physeal arrest in purpura fulminans. A report of three cases. 61
2745488 1989
755
Congenital severe protein C deficiency in adults. 61
2547423 1989
756
Diagnosis and treatment of homozygous protein C deficiency. Report of the Working Party on Homozygous Protein C Deficiency of the Subcommittee on Protein C and Protein S, International Committee on Thrombosis and Haemostasis. 61
2647943 1989
757
Meningococcal infections in children: a review of 100 cases. 61
2654860 1989
758
Homozygous protein C deficiency with delayed onset of symptoms at 7 to 10 months. 61
2660320 1989
759
Purpura fulminans. A case for heparin therapy. 61
2914417 1989
760
[Purpura fulminans. Presentation of a clinical case]. 61
2695717 1989
761
Homozygous protein C deficiency: early treatment with warfarin. 61
2618972 1989
762
Purpura and gangrene in a septic patient. Purpura fulminans secondary to pneumococcal sepsis. 61
3190260 1988
763
Purpura fulminans and transient protein C and S deficiency. 61
2970826 1988
764
Electrolyte changes caused by hydrotherapy in purpura fulminans. 61
3192606 1988
765
Purpura fulminans. A cutaneous manifestation of severe protein C deficiency. 61
3415283 1988
766
Tumor necrosis factor and interleukin-1 in the serum of children with severe infectious purpura. 61
3135497 1988
767
Purpura fulminans. 61
3389709 1988
768
Neonatal and childhood purpura fulminans: review of seven cases. 61
3286135 1988
769
Purpura fulminans in a case of protein C deficiency. 61
3366142 1988
770
Homozygous protein C deficiency: observations on the nature of the molecular abnormality and the effectiveness of warfarin therapy. 61
3340476 1988
771
Homozygous protein C deficiency in a newborn. Clinicopathologic correlation. 61
3341937 1988
772
Severe protein C deficiency in a newborn. 61
3239711 1988
773
[Purpura fulminans in a newborn infant subsequently treated with free dermal-epidermal transplants]. 61
3067261 1988
774
[Frequency of adrenal hemorrhage in fatal forms of purpura fulminans in children. Etiopathogenic and therapeutic considerations]. 61
3054802 1988
775
Purpura fulminans. 61
28134174 1988
776
[Purpura fulminans. Report of a case]. 61
3287050 1988
777
Coumarin necrosis, neonatal purpura fulminans, and protein C deficiency. 61
2961308 1987
778
Anticoagulant combination therapy of gabexate mesilate and urokinase in purpura fulminans. 61
3144146 1987
779
Brazilian purpuric fever: epidemic purpura fulminans associated with antecedent purulent conjunctivitis. Brazilian Purpuric Fever Study Group. 61
2888985 1987
780
Purpura fulminans in meningococcemia: association with acquired deficiencies of proteins C and S. 61
2956521 1987
781
Purpura fulminans. 61
3610286 1987
782
[Myocardial incompetence in meningococcal purpura in children. Early hemodynamic study]. 61
2951689 1987
783
Protein C deficiency. 61
3810223 1987
784
[Purpura fulminans in children. Current aspects]. 61
3555381 1987
785
[Purpura fulminans associated with a C7 deficiency]. 61
3578946 1987
786
[Protein C, protein S]. 61
3039876 1987
787
[Epidemiological and prognostic aspects of purpura fulminans in children. Regional survey]. 61
3588177 1987
788
Purpura fulminans in an adult. 61
3793438 1986
789
[Purpuras fulminans: development over a 15-year period]. 61
3822719 1986
790
Rhinocerebral mucormycosis in an infant with streptococcal sepsis and purpura fulminans. 61
3763421 1986
791
Clinical relevance of protein C. 61
3524711 1986
792
Purpura fulminans in a Chinese boy with congenital protein C deficiency. 61
3754634 1986
793
Disseminated intravascular coagulation and purpura fulminans in a patient with Candida sepsis. Biopsy of purpura fulminans as an aid to diagnosis of systemic Candida infection. 61
3515934 1986
794
Purpura fulminans in pneumococcal sepsis. 61
3754111 1986
795
[High-dose heparin in a patient with purpura fulminans following varicella]. 61
3774348 1986
796
Purpura fulminans produced by Aeromonas hydrophila: a case report. 61
3835694 1985
797
Protein C in thromboembolic disease. 61
3840918 1985
798
Purpura fulminans associated with Haemophilus influenzae type B infection. 61
3877879 1985
799
Homozygous protein C deficiency combined with heterozygous dysplasminogenemia found in a 21-year-old thrombophilic male. 61
3840289 1985
800
Purpura fulminans in neonates and childhood. 61
4036371 1985
801
[Purpura fulminans in the adult. Presentation of 2 cases]. 61
4033253 1985
802
Purpura fulminans. Medical, surgical, and rehabilitative considerations. 61
3971626 1985
803
Evidence for intravascular coagulation in systemic onset, but not polyarticular, juvenile rheumatoid arthritis. 61
3977974 1985
804
Neonatal purpura fulminans: a genetic disorder related to the absence of protein C in blood. 61
3838081 1985
805
Hereditary protein C deficiency. 61
3840112 1985
806
Meningococcal group Y disease in children. 61
6440125 1984
807
Magnitude of bacteremia and complement activation during Neisseria meningitidis infection: study of two co-primary cases with different clinical presentations. 61
6437810 1984
808
Purpura fulminans following late-onset group B beta-hemolytic streptococcal sepsis. 61
6383017 1984
809
Severe homozygous protein C deficiency. 61
6547978 1984
810
Purpura fulminans. 61
6481209 1984
811
The orthopaedic implications of purpura fulminans. 61
6725325 1984
812
Amputation following meningococcemia. A sequela to purpura fulminans. 61
6705382 1984
813
[Radiological case of the month: finger growth disorders, sequelae of purpura fulminans]. 61
6721655 1984
814
Inherited protein C deficiency and coumarin-responsive chronic relapsing purpura fulminans in a newborn infant. 61
6139528 1983
815
A structured approach to the management of purpura fulminans. 61
6195350 1983
816
[Purpura fulminans]. 61
6647917 1983
817
[Meningococcic purpura fulminans]. 61
6882124 1983
818
[Huge gangrenous cellulitis. Clinical symptoms-differential diagnosis--therapy]. 61
7168227 1982
819
Diagnosis and management of disseminated intravascular coagulation: the role of heparin therapy. 61
7046845 1982
820
Purpura fulminans. 61
7112693 1982
821
Purpura fulminans. 61
6461269 1982
822
Purpura fulminans in an adult. 61
7313750 1981
823
Purpura fulminans. 61
7323963 1981
824
[Purpura fulminans caused by pneumococcus in a splenectomized adult with persistence of accessory splenic tissue]. 61
7267329 1981
825
[Skin lesions and joint involvement in purpura fulminans (author's transl)]. 61
6450996 1980
826
[Purpura fulminans associated with varicella]. 61
7433047 1980
827
[Prevention of distal necrosis in purpura fulminans. Value of sodium nitroprusside and urokinase]. 61
7000028 1980
828
[Purpura fulminans]. 61
261076 1979
829
[A case of purpura fulminans associated with miliary tuberculosis (author's transl)]. 61
554010 1979
830
Massive skin necrosis in Rocky Mountain spotted fever. 61