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MCID: PRL012
MIFTS: 23

Purulent Acute Otitis Media

Categories: Ear diseases
Genes Tissues Related diseases Publications Drugs
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Aliases & Classifications for Purulent Acute Otitis Media

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MalaCards integrated aliases for Purulent Acute Otitis Media:

Name: Purulent Acute Otitis Media 12 15
Acute Suppurative Otitis Media 72 33

Classifications:

MalaCards categories:
Anatomical: Ear diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:10435
ICD9CM 35 382.02
ICD10 33 H66.0
UMLS 72 C0155439 C0271431
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Summaries for Purulent Acute Otitis Media

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Disease Ontology : 12 A suppurative otitis media with sudden onset and a short course.

MalaCards based summary : Purulent Acute Otitis Media, also known as acute suppurative otitis media, is related to otitis media and suppurative otitis media. An important gene associated with Purulent Acute Otitis Media is PDZD11 (PDZ Domain Containing 11). The drugs carbamide peroxide and Pazufloxacin have been mentioned in the context of this disorder. Affiliated tissues include bone, brain and tonsil.

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Related Diseases for Purulent Acute Otitis Media

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Diseases in the Purulent Acute Otitis Media family:

Chronic Purulent Otitis Media

Diseases related to Purulent Acute Otitis Media via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 otitis media 11.0
2 suppurative otitis media 11.0
3 meningitis 10.4
4 mastoiditis 10.3
5 haemophilus influenzae 10.3
6 drug allergy 10.3
7 meningoencephalitis 10.3
8 facial paralysis 10.3
9 chronic purulent otitis media 10.3
10 kearns-sayre syndrome 10.1
11 nasopharyngeal carcinoma 10.1
12 osteomyelitis 10.1
13 petrositis 10.1
14 streptococcal meningitis 10.1
15 leukemia 10.1
16 tolosa-hunt syndrome 10.1
17 exostosis 10.1
18 cellulitis 10.1
19 48,xyyy 10.1
20 tuberculous meningitis 10.1

Graphical network of the top 20 diseases related to Purulent Acute Otitis Media:



Diseases related to Purulent Acute Otitis Media
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Symptoms & Phenotypes for Purulent Acute Otitis Media

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Drugs & Therapeutics for Purulent Acute Otitis Media

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Drugs for Purulent Acute Otitis Media (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 9)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
carbamide peroxide Approved Phase 1 124-43-6
2 Pazufloxacin Investigational Phase 1 127045-41-4
3 Fluoroquinolones Phase 1
4 Anti-Bacterial Agents Phase 1
5 Anti-Infective Agents, Local Phase 1
6 Nucleic Acid Synthesis Inhibitors Phase 1
7 Topoisomerase Inhibitors Phase 1
8 Antitubercular Agents Phase 1
9 Anti-Infective Agents Phase 1

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Single Dose Phase I Clinical Study of Pazufloxacin Mesilate Ear Drops for the Patients With Otitis Media Unknown status NCT02592096 Phase 1 0.1% Pazufloxacin Mesilate Ear Drops;0.3% Pazufloxacin Mesilate Ear Drops;0.5% Pazufloxacin Mesilate Ear Drops;Pazufloxacin mesilate injection

Search NIH Clinical Center for Purulent Acute Otitis Media

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Genetic Tests for Purulent Acute Otitis Media

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Anatomical Context for Purulent Acute Otitis Media

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MalaCards organs/tissues related to Purulent Acute Otitis Media:

41
Bone, Brain, Tonsil, Neutrophil
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Publications for Purulent Acute Otitis Media

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Articles related to Purulent Acute Otitis Media:

(show top 50) (show all 151)
# Title Authors PMID Year
1
Pattern of tympanic membrane perforation in a tertiary hospital in Nigeria. 38
30074009 2018
2
WITHDRAWN: Grommets (ventilation tubes) for recurrent acute otitis media in children. 38
29624209 2018
3
Pediatric Acute Otitis Media in the Era of Pneumococcal Vaccination. 38
28349737 2017
4
Facial Nerve Paralysis in Acute Suppurative Otitis Media-Management. 38
28239580 2017
5
[Acute suppurative otitis media caused by pasteurella multocida :a case report]. 38
29871210 2017
6
[The specific features of the clinical course of acute suppurative otitis media of viral and mixed viral-bacterial etiology in the children of the preschool age]. 38
29072655 2017
7
[The diagnostics and treatment of otogenic intracranial complications]. 38
27876726 2016
8
Suppurative labyrinthitis associated with otitis media: 26 years' experience. 38
26718959 2016
9
Prevalence of ear diseases in the children of Delhi. 38
25883066 2015
10
[Pulmonary complications in pediatric patients with primary immunodeficiency]. 38
25946525 2015
11
[Cholesteatoma of the external and middle ear in the childhood]. 38
25909669 2015
12
Petrositis With Bilateral Abducens Nerve Palsies complicated by Acute Otitis Media. 38
24587883 2014
13
Montelukast is as effective as penicillin in treatment of acute otitis media: an experimental rat study. 38
24048018 2013
14
Acute otitis media in infants younger than three months not vaccinated against Streptococcus pneumoniae. 38
23601926 2013
15
Three years audit of the emergency patients in the department of ENT of a rural medical college. 38
23360039 2012
16
[Transmeatal aerodynamical otoendoscopy for otitis media]. 38
23250522 2012
17
Scarlet fever caused by community-associated methicillin-resistant Staphylococcus aureus. 38
21813926 2011
18
[First experience with the use of tympanostomy for the management of acute otitis media in children]. 38
22433702 2011
19
Acute infectious complications in stapes surgery. 38
21866741 2010
20
Interferon-gamma in suppurative otitis media: significance of otorrhoea type and disease outcome. 38
19640314 2009
21
The role of retinol in the etiology and outcome of suppurative otitis media. 38
18704470 2009
22
[The use of sinupret in the combined treatment of acute otitis media in children]. 38
19491798 2009
23
Pattern of tympanic membrane perforation in ibadan: a retrospective study. 38
25161451 2008
24
Grommets (ventilation tubes) for recurrent acute otitis media in children. 38
18843668 2008
25
Alloiococcus otitidis--otitis media pathogen or normal bacterial flora? 38
19024598 2008
26
Acute suppurative otitis media. 38
18572776 2008
27
Acute suppurative otitis media: an unusual cause of orbital apex syndrome. 38
19085305 2008
28
The morphology of central tympanic membrane perforations. 38
18298012 2007
29
[Child acute otitis media]. 38
18092722 2007
30
[Epidemiological survey of pneumococcus serotypes in pediatric patients with acute suppurative otitis media]. 38
17338318 2007
31
Antimicrobial utilization pattern in out patient services of ENT department of tertiary care hospital of Eastern Nepal. 38
16449838 2005
32
Cervicofacial nocardiosis in an immunocompetent child. 38
16279004 2005
33
Meningitis with bilateral acute suppurative otitis media caused by Group A streptococcus. 38
15695870 2005
34
Histologic evaluation of the tissue seal and biologic response around cochlear implant electrodes in the human. 38
15129102 2004
35
Adam Politzer (1835-1920): his medical studies and publications in Hungarian. 38
14724496 2004
36
Streptococcus acidominimus infection in a child causing Gradenigo syndrome. 38
12791460 2003
37
Current status of bacterial resistance in the otolaryngology field: results from the Second Nationwide Survey in Japan. 38
12673407 2003
38
Short-course antimicrobial therapy of respiratory tract infections. 38
14498754 2003
39
Abducens nerve palsy as the sole presenting symptom of petrous apicitis. 38
12437811 2002
40
[Otitis media with effusion: a study of 346 cases in an outpatient clinic]. 38
12235880 2002
41
Diagnosis and treatment of the child with a draining ear. 38
12122378 2002
42
Epidemiology of acute otitis media among Saudi children. 38
11852124 2002
43
Assessing diagnostic accuracy and tympanocentesis skills in the management of otitis media. 38
11576009 2001
44
Cefdinir vs. amoxicillin/clavulanic acid in the treatment of suppurative acute otitis media in children. 38
11144399 2000
45
A new pathogenesis of mesotympanic (congenital) cholesteatoma. 38
11081605 2000
46
Short-Course antimicrobial therapy for upper respiratory tract infections. 38
10929916 2000
47
[HSP70 expression of middle ear mucosa in acute suppurative otitis media]. 38
12541495 2000
48
Intratemporal and intracranial complications of acute suppurative otitis media in children: renewed interest. 38
10577787 1999
49
Effects of active immunization with a pneumococcal surface protein (PspA) and of locally applied antibodies in experimental otitis media. 38
10450055 1999
50
Bilateral acute suppurative otitis media: the stage of hyperemia. 38
10188346 1999
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Variations for Purulent Acute Otitis Media

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Expression for Purulent Acute Otitis Media

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Search GEO for disease gene expression data for Purulent Acute Otitis Media.
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Pathways for Purulent Acute Otitis Media

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GO Terms for Purulent Acute Otitis Media

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Sources for Purulent Acute Otitis Media

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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