MCID: PRL018
MIFTS: 24

Purulent Endophthalmitis

Categories: Eye diseases

Aliases & Classifications for Purulent Endophthalmitis

MalaCards integrated aliases for Purulent Endophthalmitis:

Name: Purulent Endophthalmitis 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:9724
ICD9CM 36 360.0 360.00
SNOMED-CT 69 41720003
ICD10 34 H44.0 H44.00
UMLS 74 C0259800

Summaries for Purulent Endophthalmitis

MalaCards based summary : Purulent Endophthalmitis is related to endophthalmitis and chronic endophthalmitis. An important gene associated with Purulent Endophthalmitis is MUC13 (Mucin 13, Cell Surface Associated), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include eye, pineal and temporal lobe, and related phenotypes are homeostasis/metabolism and nervous system

Related Diseases for Purulent Endophthalmitis

Diseases related to Purulent Endophthalmitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 35)
# Related Disease Score Top Affiliating Genes
1 endophthalmitis 31.5 MRAP PRF1 VEGFA
2 chronic endophthalmitis 31.0 CCNE1 MRAP
3 acute endophthalmitis 29.4 C4A IVD NDUFS4 PRF1 TOR1A TOR1B
4 immunodeficiency due to a classical component pathway complement deficiency 10.3 C4A C4B
5 juvenile dermatitis herpetiformis 10.3 C4A C4B
6 epilepsy, familial temporal lobe, 2 10.3 C4A C4B
7 strongyloidiasis 10.3 CD79A IVD
8 discitis 10.3 IVD MRAP
9 septicemic plague 10.2 C4B CCNE1
10 bowenoid papulosis 10.2 CCNE1 TERT
11 bursitis 10.2 MRAP NDUFS4
12 hypersensitivity reaction type iii disease 10.2 C4A C4B CD79A
13 pancreatic serous cystadenoma 10.1 SYP VEGFA
14 osgood-schlatter's disease 10.1 MRAP PRF1
15 macular dystrophy, dominant cystoid 10.1 MRAP VEGFA
16 immunoglobulin alpha deficiency 10.1 C4A CD79A TOR1A
17 cancer-associated retinopathy 10.1 SAG VEGFA
18 glomerulonephritis 10.1 C4A C4B CD79A
19 pineal gland cancer 10.1 SAG SYP
20 mediastinal cancer 10.1 CD79A SYP
21 blood group, globoside system 10.1 MRAP PRF1 VEGFA
22 rubeosis iridis 10.0 NDUFS4 SYP VEGFA
23 renal tuberculosis 10.0 CD79A CTSL MRAP
24 pineocytoma 10.0 SAG SYP
25 chorioretinitis 10.0 MRAP SAG
26 sella turcica neoplasm 10.0 MRAP SYP
27 tuberculum sellae meningioma 10.0 MRAP SYP
28 acinar cell cystadenocarcinoma 10.0 MUC5AC SYP
29 orbital tenonitis 10.0
30 sympathetic ophthalmia 10.0
31 pediatric systemic lupus erythematosus 10.0 C4A C4B
32 supratentorial cancer 9.9 SYP TERT VEGFA
33 cerebrum cancer 9.9 SYP TERT VEGFA
34 mucinous ovarian cystadenoma 9.8 MUC5AC SYP
35 panophthalmitis 8.9 CD79A CTSL FBXO7 MUC5AC SAG SUCLG2

Comorbidity relations with Purulent Endophthalmitis via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Endophthalmitis
Corneal Ulcer Hypopyon
Perforated Corneal Ulcer

Graphical network of the top 20 diseases related to Purulent Endophthalmitis:



Diseases related to Purulent Endophthalmitis

Symptoms & Phenotypes for Purulent Endophthalmitis

MGI Mouse Phenotypes related to Purulent Endophthalmitis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.93 C4B CD79A FBXO7 IVD MUC5AC NDUFS4
2 nervous system MP:0003631 9.65 CCNE1 CD79A NDUFS4 NR2E3 PRF1 SAG
3 normal MP:0002873 9.23 CCNE1 CD79A NDUFS4 PRF1 SYP TERT

Drugs & Therapeutics for Purulent Endophthalmitis

Search Clinical Trials , NIH Clinical Center for Purulent Endophthalmitis

Genetic Tests for Purulent Endophthalmitis

Anatomical Context for Purulent Endophthalmitis

MalaCards organs/tissues related to Purulent Endophthalmitis:

42
Eye, Pineal, Temporal Lobe

Publications for Purulent Endophthalmitis

Articles related to Purulent Endophthalmitis:

# Title Authors Year
1
Early vitrectomy in the treatment of post-operative purulent endophthalmitis. ( 3499048 )
1987
2
Puerperal sepsis leading to bilateral fulminating purulent endophthalmitis with tenonitis. ( 4757342 )
1973
3
Sympathetic ophthalmia following purulent endophthalmitis (postcataract extraction). ( 14877974 )
1951

Variations for Purulent Endophthalmitis

Expression for Purulent Endophthalmitis

Search GEO for disease gene expression data for Purulent Endophthalmitis.

Pathways for Purulent Endophthalmitis

Pathways related to Purulent Endophthalmitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.46 FBXO7 SAG SYP TOR1A

GO Terms for Purulent Endophthalmitis

Biological processes related to Purulent Endophthalmitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 eye photoreceptor cell development GO:0042462 9.16 NR2E3 VEGFA
2 positive regulation of apoptotic cell clearance GO:2000427 8.96 C4A C4B
3 nuclear membrane organization GO:0071763 8.62 TOR1A TOR1B

Sources for Purulent Endophthalmitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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