MCID: PRL018
MIFTS: 23

Purulent Endophthalmitis

Categories: Eye diseases

Aliases & Classifications for Purulent Endophthalmitis

MalaCards integrated aliases for Purulent Endophthalmitis:

Name: Purulent Endophthalmitis 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:9724
ICD10 33 H44.0 H44.00
ICD9CM 35 360.0 360.00
SNOMED-CT 68 41720003
UMLS 73 C0259800

Summaries for Purulent Endophthalmitis

MalaCards based summary : Purulent Endophthalmitis is related to endophthalmitis and chronic endophthalmitis. An important gene associated with Purulent Endophthalmitis is MUC13 (Mucin 13, Cell Surface Associated), and among its related pathways/superpathways is Neuroscience. Affiliated tissues include eye, pineal and small intestine, and related phenotypes are homeostasis/metabolism and normal

Related Diseases for Purulent Endophthalmitis

Diseases related to Purulent Endophthalmitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 endophthalmitis 31.3 MRAP OPTN PRF1 VEGFA
2 chronic endophthalmitis 30.8 CCNE1 MRAP
3 acute endophthalmitis 29.8 C4A IVD NDUFS4 PRF1 TOR1A TOR1B
4 hydrophthalmos 10.2 FBXO7 OPTN
5 strongyloidiasis 10.2 CD79A IVD
6 discitis 10.2 IVD MRAP
7 osgood-schlatter's disease 10.2 MRAP PRF1
8 neovascular glaucoma 10.1 OPTN VEGFA
9 cancer-associated retinopathy 10.1 SAG VEGFA
10 bursitis 10.1 MRAP NDUFS4
11 bowenoid papulosis 10.1 CCNE1 TERT
12 macular dystrophy, dominant cystoid 10.1 MRAP VEGFA
13 immunoglobulin alpha deficiency 10.1 C4A CD79A TOR1A
14 pancreatic serous cystadenoma 10.1 SYP VEGFA
15 pineal gland cancer 10.1 SAG SYP
16 chorioretinitis 10.0 MRAP OPTN SAG
17 pineocytoma 10.0 SAG SYP
18 uveal disease 10.0 MRAP OPTN SAG
19 mediastinal cancer 10.0 CD79A SYP
20 sella turcica neoplasm 10.0 MRAP SYP
21 tuberculum sellae meningioma 10.0 MRAP SYP
22 rubeosis iridis 10.0 NDUFS4 SYP VEGFA
23 acinar cell cystadenocarcinoma 10.0 MUC5AC SYP
24 papillary ependymoma 10.0 SAG SYP
25 renal tuberculosis 10.0 CD79A CTSL MRAP
26 sympathetic ophthalmia 10.0
27 blood group, globoside system 10.0 MRAP OPTN PRF1 VEGFA
28 pineoblastoma 10.0 SAG SYP
29 nervous system disease 9.9 OPTN SYP VEGFA
30 mucinous ovarian cystadenoma 9.9 MUC5AC SYP
31 benign meningioma 9.9 CTSL TERT
32 supratentorial cancer 9.9 SYP TERT VEGFA
33 spermatocele 9.9 SYP TERT
34 cerebrum cancer 9.9 SYP TERT VEGFA
35 soft tissue sarcoma 9.9 TERT VEGFA
36 panophthalmitis 9.2 CD79A CTSL FBXO7 MUC5AC OPTN SAG

Comorbidity relations with Purulent Endophthalmitis via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Endophthalmitis
Corneal Ulcer Hypopyon
Perforated Corneal Ulcer

Graphical network of the top 20 diseases related to Purulent Endophthalmitis:



Diseases related to Purulent Endophthalmitis

Symptoms & Phenotypes for Purulent Endophthalmitis

MGI Mouse Phenotypes related to Purulent Endophthalmitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.73 CD79A FBXO7 IVD MUC5AC NDUFS4 OPTN
2 normal MP:0002873 9.23 CCNE1 CD79A NDUFS4 PRF1 SYP TERT

Drugs & Therapeutics for Purulent Endophthalmitis

Search Clinical Trials , NIH Clinical Center for Purulent Endophthalmitis

Genetic Tests for Purulent Endophthalmitis

Anatomical Context for Purulent Endophthalmitis

MalaCards organs/tissues related to Purulent Endophthalmitis:

41
Eye, Pineal, Small Intestine

Publications for Purulent Endophthalmitis

Articles related to Purulent Endophthalmitis:

# Title Authors Year
1
Early vitrectomy in the treatment of post-operative purulent endophthalmitis. ( 3499048 )
1987
2
Puerperal sepsis leading to bilateral fulminating purulent endophthalmitis with tenonitis. ( 4757342 )
1973
3
Sympathetic ophthalmia following purulent endophthalmitis (postcataract extraction). ( 14877974 )
1951

Variations for Purulent Endophthalmitis

Expression for Purulent Endophthalmitis

Search GEO for disease gene expression data for Purulent Endophthalmitis.

Pathways for Purulent Endophthalmitis

Pathways related to Purulent Endophthalmitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.56 FBXO7 OPTN SAG SYP TOR1A

GO Terms for Purulent Endophthalmitis

Biological processes related to Purulent Endophthalmitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nuclear membrane organization GO:0071763 8.62 TOR1A TOR1B

Molecular functions related to Purulent Endophthalmitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.1 MRAP OPTN PRF1 SYP TERT VEGFA

Sources for Purulent Endophthalmitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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