Aliases & Classifications for Pylorospasm

MalaCards integrated aliases for Pylorospasm:

Name: Pylorospasm 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:12072
ICD9CM 34 537.81
SNOMED-CT 67 335002
ICD10 32 K31.3
UMLS 71 C0152163

Summaries for Pylorospasm

MalaCards based summary : Pylorospasm is related to gastroparesis and volvulus of midgut, and has symptoms including dyspepsia, spasm and gastric irritation. An important gene associated with Pylorospasm is MLN (Motilin), and among its related pathways/superpathways is Semaphorin Signaling. Affiliated tissues include small intestine.

Related Diseases for Pylorospasm

Diseases related to Pylorospasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
# Related Disease Score Top Affiliating Genes
1 gastroparesis 30.1 MLNR MLN
2 volvulus of midgut 30.0 MLNR MLN
3 pyloric stenosis 10.5
4 hypertrophic pyloric stenosis 10.3
5 functional colonic disease 10.2 MLNR MLN
6 rumination disorder 10.2 MLNR MLN
7 colonic pseudo-obstruction 10.2 MLNR MLN
8 functional gastric disease 10.1 MLNR MLN
9 diabetic autonomic neuropathy 10.1 MLNR MLN
10 cascade stomach 10.1
11 optic nerve neoplasm 9.9 RASA2 LZTR1
12 gastroesophageal reflux 9.9
13 anorexia nervosa 9.9
14 muscle hypertrophy 9.9
15 villous adenoma 9.9
16 urinary tract infection 9.9
17 ileus 9.9
18 neurofibromatosis-noonan syndrome 9.9 SOS2 A2ML1
19 intestinal pseudo-obstruction 9.9 MLNR MLN
20 ohdo syndrome 9.8 UBE3B KAT6B
21 ohdo syndrome, sbbys variant 9.8 UBE3B KAT6B
22 eyelid disease 9.7 UBE3B KAT6B
23 noonan syndrome-like disorder with loose anagen hair 2 9.7 SOS2 LZTR1 A2ML1
24 noonan syndrome-like disorder with loose anagen hair 9.7 SOS2 LZTR1 A2ML1
25 blepharophimosis 9.7 UBE3B KAT6B
26 juvenile myelomonocytic leukemia 9.5 SOS2 RASA2 LZTR1
27 pulmonary valve disease 9.4 SOS2 RASA2 LZTR1 A2ML1
28 pulmonary valve stenosis 9.4 SOS2 RASA2 LZTR1 A2ML1
29 noonan syndrome with multiple lentigines 9.4 SOS2 RASA2 LZTR1 A2ML1
30 noonan syndrome 1 9.4 SOS2 RASA2 LZTR1 A2ML1
31 cardiofaciocutaneous syndrome 1 9.0 SOS2 RASA2 LZTR1 KAT6B A2ML1
32 rasopathy 9.0 SOS2 RASA2 LZTR1 KAT6B A2ML1

Comorbidity relations with Pylorospasm via Phenotypic Disease Network (PDN):


Esophagitis

Graphical network of the top 20 diseases related to Pylorospasm:



Diseases related to Pylorospasm

Symptoms & Phenotypes for Pylorospasm

UMLS symptoms related to Pylorospasm:


dyspepsia, spasm, gastric irritation, upset stomach

Drugs & Therapeutics for Pylorospasm

Search Clinical Trials , NIH Clinical Center for Pylorospasm

Genetic Tests for Pylorospasm

Anatomical Context for Pylorospasm

MalaCards organs/tissues related to Pylorospasm:

40
Small Intestine

Publications for Pylorospasm

Articles related to Pylorospasm:

(show top 50) (show all 122)
# Title Authors PMID Year
1
Relationship of Motor Mechanisms to Gastroparesis Symptoms: Towards Individualized Treatment. 61
33566731 2021
2
Techniques and devices for the endoscopic treatment of gastroparesis (with video). 61
32684298 2020
3
Pyloric distensibility measurement after gastric surgery: Which surgeries are associated with pylorospasm? 61
31916346 2020
4
Stent Placement for the Treatment of Gastroparesis. 61
30396520 2019
5
An ileo-ileal intussusception secondary to polypoid lipoma in a child, a case report and review of the literature. 61
30927709 2019
6
State of the art review with literature summary on gastric peroral endoscopic pyloromyotomy for gastroparesis. 61
29806114 2018
7
Formulation development and evaluation of nifedipine as pylorospasm inhibitor. 61
29429379 2018
8
Gastric peroral endoscopic myotomy for pylorospasm: Case report and literature review. 61
28727260 2017
9
Synchronous perforations of the oesophagus and stomach by air insufflation: an uncommon complication of endoscopic dilation. 61
27799228 2016
10
Novel Diet, Drugs, and Gastric Interventions for Gastroparesis. 61
26762845 2016
11
Peroral endoscopic pyloromyotomy accelerates gastric emptying in healthy pigs: proof of concept. 61
27556100 2016
12
Methicillin-Resistant Staphylococcus aureus Subhepatic Abscess Presenting as Pylorospasm in a Neonate. 61
26835566 2016
13
Diabetic gastroparesis. 61
25667022 2015
14
Lacidipine encapsulated gastroretentive microspheres prepared by chemical denaturation for pylorospasm. 61
18720200 2009
15
Pylorospasm (simulating hypertrophic pyloric stenosis) with secondary gastroesophageal reflux. 61
18528245 2008
16
[Gastroesophageal reflux in children]. 61
17601041 2007
17
Minimally invasive esophagectomy for cancer: prospective evaluation of laparoscopic gastric mobilization. 61
16850150 2006
18
Delayed gastric emptying: whom to test, how to test, and what to do. 61
16836948 2006
19
[Minimally invasive esophagectomy: prospective evaluation of laparoscopic gastric mobilization]. 61
16466684 2006
20
Is pylorospasm a cause of delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy? 61
15827814 2005
21
Real time high resolution magnetic resonance imaging for the assessment of gastric motility disorders. 61
15306580 2004
22
Delayed salicylate toxicity at 35 hours without early manifestations following a single salicylate ingestion. 61
15173556 2004
23
The sonographic double-track sign: not pathognomonic for hypertrophic pyloric stenosis; can be seen in pylorospasm. 61
15154530 2004
24
Gastroparesis and neuromuscular disorders of the stomach. 61
16481977 2003
25
Congenital hypertrophic pyloric stenosis. 61
12356225 2002
26
Gastrin, somatostatin and infantile hypertrophic pyloric stenosis. 61
11529535 2001
27
Thoracoscopic truncal vagotomy. 61
11232981 2000
28
Botulinum toxin for spastic gastrointestinal disorders. 61
11030639 1999
29
[Omentoplasty in surgical management of postpulmonectomy pleural empyema]. 61
11484240 1999
30
[Suprapyloric resection of stomach in patients with ulcer disease]. 61
10050505 1999
31
Ultrasonography of pylorospasm: findings may simulate hypertrophic pyloric stenosis. 61
9805307 1998
32
Effects of octreotide on manometric variables in patients with neuropathic abnormalities of the small bowel. 61
9286228 1997
33
[Functional, organic and histologic changes in the stomach in diabetic patients in relation to the presence of diabetic neuropathy]. 61
9019625 1996
34
Hypertrophic pyloric stenosis in the infant without a palpable olive: accuracy of sonographic diagnosis. 61
7972822 1994
35
Gastric retention of enteric-coated magnesium chloride tablets. 61
7949504 1994
36
[Clinical studies of intra-thoracic stomach function in patients after esophagectomy and reconstruction by whole stomach]. 61
8223003 1993
37
[The late examination results in children with pylorospasm and dyskinesia of the proximal sections of the small intestine]. 61
1294794 1992
38
Nitric oxide synthase activity in infantile hypertrophic pyloric stenosis. 61
1378938 1992
39
[Balloon dilatation of benign esophageal stenoses]. 61
1849292 1991
40
[Surgical treatment of gastroesophageal reflux by modified Hill's posterior cardiopexy. Apropos of 441 cases]. 61
2100119 1990
41
Incidence of infantile hypertrophic pyloric stenosis in Saskatchewan, 1970-85. 61
2914260 1989
42
[A new method of differential diagnosis and treatment of pyloric spasm]. 61
2797837 1989
43
Valvuloplasty plus fundoplasty to prevent esophageal regurgitation in esophagogastrostomy after proximal gastrectomy. 61
3752383 1986
44
Pyloric dysfunction in diabetics with recurrent nausea and vomiting. 61
3699409 1986
45
Gastric damage from ingested acid in children. 61
4057013 1985
46
Symptomatic gastroduodenal pancreatic rest in children. 61
6481592 1984
47
Effects of rociverine and other spasmolytic agents on caerulein-induced delay in gastric emptying in the conscious rat. 61
7114969 1982
48
Radiographic abnormalities after gastric bypass. 61
6976728 1982
49
Short segment pyloric narrowing. Pylorospasm or pyloric stenosis? 61
7254915 1981
50
Peptic ulcer disease in early infancy: clinical presentation and roentgenographic features. 61
7211360 1980

Variations for Pylorospasm

Expression for Pylorospasm

Search GEO for disease gene expression data for Pylorospasm.

Pathways for Pylorospasm

Pathways related to Pylorospasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.28 SOS2 RASA2

GO Terms for Pylorospasm

Biological processes related to Pylorospasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of Ras protein signal transduction GO:0046580 8.62 RASA2 LZTR1

Sources for Pylorospasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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