Home
User Guide
What's in a MalaCard Search Guide Our Sources
Analysis Tools
GeneCards GeneAnalytics GeneAlaCart PathCards VarElect TGex
News and Views Disease Lists/Categories
About
About MalaCards Our Publications Academic Licensing Weizmann Institute LifeMap Discovery® Terms of Use MalaCards Team
MCID: PYD002
MIFTS: 51

Pyoderma

Categories: Skin diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
Sources

Aliases & Classifications for Pyoderma

About this section

MalaCards integrated aliases for Pyoderma:

Name: Pyoderma 12 55 44 15 73

Classifications:

MalaCards categories:
Anatomical: Skin diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:4223
ICD10 33 L08.0
ICD9CM 35 686.0 686.00
MeSH 44 D011711
UMLS 73 C0034212
Sources

Summaries for Pyoderma

About this section
Disease Ontology : 12 Pyoderma is a skin infectious disease where the infection is pyogenic causing the formation of pus.

MalaCards based summary : Pyoderma is related to pyogenic arthritis, pyoderma gangrenosum and acne and ileocolitis, and has symptoms including exanthema, pruritus and pustular rash. An important gene associated with Pyoderma is PSTPIP1 (Proline-Serine-Threonine Phosphatase Interacting Protein 1), and among its related pathways/superpathways are TGF-Beta Pathway and Innate Immune System. The drugs Infliximab and Anti-Bacterial Agents have been mentioned in the context of this disorder. Affiliated tissues include skin, neutrophil and lung, and related phenotypes are hematopoietic system and immune system

Sources

Related Diseases for Pyoderma

About this section

Diseases related to Pyoderma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 302)
# Related Disease Score Top Affiliating Genes
1 pyogenic arthritis, pyoderma gangrenosum and acne 34.8 IL1R1 PSTPIP1
2 ileocolitis 32.2 NOD2 TNF
3 impetigo 31.4 DSG1 IL36RN
4 pyoderma gangrenosum 31.2 CXCL8 IFNA2 ITGB2 MEFV MMP10 NOD2
5 ulcerative colitis 30.8 CXCL8 NOD2 TNF
6 colitis 30.7 CXCL8 NOD2 TNF
7 scleritis 30.6 ITGB2 TNF
8 vasculitis 30.5 IFNA2 MEFV TNF
9 sapho syndrome 30.4 CXCL8 NOD2
10 wegener granulomatosis 30.3 CXCL8 ITGB2 TNF
11 pouchitis 30.2 CXCL8 NOD2
12 erysipelas 30.2 MEFV TNF
13 arthritis 30.1 CXCL8 MMP1 PSTPIP1 TNF
14 cellulitis 30.0 IL1R1 TNF
15 periodontitis 29.5 CXCL8 MMP1 TNF
16 periodontal disease 29.5 CXCL8 MMP1 TNF
17 inflammatory bowel disease 29.3 CXCL8 IL1R1 MMP1 NOD2 TNF
18 rheumatoid arthritis 28.9 CXCL8 IL1R1 ITGB2 MMP1 TNF
19 skin disease 28.0 CXCL8 DSG1 IL36RN TNF
20 pyogenic sterile arthritis, pyoderma gangrenosum, and acne 12.2
21 pyoderma gangrenosum-acne-suppurative hidradenitis syndrome 12.0
22 crohn's disease 11.2
23 gapo syndrome 11.2
24 cutaneous diphtheria 11.2
25 corticosteroid-sensitive aseptic abscesses 11.2
26 actinic prurigo 11.0
27 polydactyly, postaxial, type a1 10.9
28 papillon-lefevre syndrome 10.9
29 systemic onset juvenile idiopathic arthritis 10.8 MEFV TNF
30 autoinflammation, panniculitis, and dermatosis syndrome 10.8 MEFV TNF
31 vulvar vestibulitis syndrome 10.7 IL1R1 TNF
32 tungiasis 10.7 CXCL8 TNF
33 streptococcal toxic-shock syndrome 10.7 CXCL8 TNF
34 familial cold autoinflammatory syndrome 1 10.7 IL1R1 MEFV
35 trichuriasis 10.6 CXCL8 TNF
36 haemophilus influenzae 10.6 CXCL8 TNF
37 sweat gland disease 10.6 PSTPIP1 TNF
38 granulomatous dermatitis 10.6 NOD2 TNF
39 relapsing fever 10.6 MEFV TNF
40 periodic fever, familial, autosomal dominant 10.6 MEFV TNF
41 clonorchiasis 10.6 CXCL8 TNF
42 meconium aspiration syndrome 10.6 CXCL8 TNF
43 mycobacterium abscessus 10.6 CXCL8 TNF
44 louse-borne relapsing fever 10.5 CXCL8 TNF
45 dental pulp disease 10.5 CXCL8 TNF
46 sebaceous gland disease 10.5 CXCL8 PSTPIP1
47 adult-onset still's disease 10.5 IL1R1 MEFV TNF
48 inflammatory bowel disease 3 10.4 NOD2 TNF
49 aseptic meningitis 10.4 CXCL8 IL1R1 TNF
50 transverse myelitis 10.4 CXCL8 TNF

Comorbidity relations with Pyoderma via Phenotypic Disease Network (PDN):


Acute Cystitis Decubitus Ulcer
Deficiency Anemia Heart Disease
Peripheral Vascular Disease

Graphical network of the top 20 diseases related to Pyoderma:



Diseases related to Pyoderma
Sources

Symptoms & Phenotypes for Pyoderma

About this section

UMLS symptoms related to Pyoderma:


exanthema, pruritus, pustular rash

MGI Mouse Phenotypes related to Pyoderma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.76 PSTPIP1 TNF BTK IL1R1 IL36RN ITGB2
2 immune system MP:0005387 9.65 BTK IL1R1 IL36RN ITGB2 MEFV MMP1
3 integument MP:0010771 9.17 BTK DSG1 IL1R1 IL36RN ITGB2 MEFV
Sources

Drugs & Therapeutics for Pyoderma

About this section

Drugs for Pyoderma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 43)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Infliximab Approved Phase 4,Not Applicable 170277-31-3
2 Anti-Bacterial Agents Phase 4,Phase 3
3 Anti-Infective Agents Phase 4,Phase 3,Phase 2
4 Gastrointestinal Agents Phase 4,Not Applicable
5 Dermatologic Agents Phase 4,Phase 2,Not Applicable
6 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Not Applicable
7
Minocycline Approved, Investigational Phase 3 10118-90-8 5281021
8
Ivermectin Approved, Investigational, Vet_approved Phase 3,Phase 2 70288-86-7 6474909
9
Adalimumab Approved Phase 2, Phase 3,Phase 3 331731-18-1 16219006
10
Azathioprine Approved Phase 3 446-86-6 2265
11
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
12 Mesalamine Phase 3,Phase 2 89-57-6
13 Analgesics Phase 3
14 glucocorticoids Phase 3
15 Analgesics, Non-Narcotic Phase 3
16 N-Methylaspartate Phase 3
17 Hormone Antagonists Phase 3
18 Hormones Phase 3
19 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
20 Peripheral Nervous System Agents Phase 3
21 Pharmaceutical Solutions Phase 3,Phase 2
22 Immunosuppressive Agents Phase 3,Phase 2
23 Antiparasitic Agents Phase 3,Phase 2
24 Liver Extracts Phase 3
25 Anti-Inflammatory Agents Phase 3,Phase 2
26 Anti-Inflammatory Agents, Non-Steroidal Phase 3
27 Antimetabolites Phase 3
28 Antimetabolites, Antineoplastic Phase 3
29 Antineoplastic Agents, Hormonal Phase 3
30 alanine Nutraceutical Phase 3
31 Aspartic Acid Nutraceutical Phase 3
32
Tacrolimus Approved, Investigational Phase 2 104987-11-3 445643 439492
33 Antibodies Phase 2,Phase 1
34 Immunoglobulins Phase 2,Phase 1
35 Antibodies, Monoclonal Phase 2,Phase 1
36 Calcineurin Inhibitors Phase 2
37
Amoxicillin Approved, Vet_approved 26787-78-0 33613
38
Certolizumab pegol Approved 428863-50-7
39 Vedolizumab Approved 943609-66-3
40 Clavulanic Acid
41 Amoxicillin-Potassium Clavulanate Combination
42 Vaccines
43 beta-Lactamase Inhibitors

Interventional clinical trials:

(show all 37)
# Name Status NCT ID Phase Drugs
1 Infliximab for the Prevention of Recurrent Crohn's Disease After Surgery Completed NCT00688636 Phase 4 infliximab;placebo
2 Sisomicin Cream Vs Nadifloxacin Cream in Primary Pyodermas (Study P04460) Withdrawn NCT00202891 Phase 4 sisomicin
3 Minocycline Therapy for Lung Scarring in Patients With Idiopathic Pulmonary Fibrosis - a Pilot Study Unknown status NCT00203697 Phase 3 minocycline
4 A Comparison of Once a Day Dose Compared to 2 Doses/Day Completed NCT00505778 Phase 3 Mesalamine Once-Daily;Mesalamine Twice-Daily
5 A Study of Adalimumab for the Maintenance of Clinical Remission in Japanese Subjects With Crohn's Disease Completed NCT00445432 Phase 2, Phase 3
6 A Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT01068158 Phase 3 0.5% Ivermectin Cream;Placebo control
7 A Safety and Efficacy Study Comparing 0.5% Ivermectin Cream to a Vehicle Control in Subjects With Head Lice Infestation Completed NCT01066585 Phase 3 Ivermectin Cream;vehicle control
8 Efficacy and Safety of Two Treatment Algorithms in Adults With Moderate to Severe Crohn's Disease Completed NCT01235689 Phase 3 Prednisone;Azathioprine
9 A Study Assessing the Efficacy and Safety of Adalimumab in Active Ulcer(s) of Pyoderma Gangrenosum in Participants in Japan Recruiting NCT03311464 Phase 3 adalimumab
10 An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum Terminated NCT02326740 Phase 3 gevokizumab;Placebo;gevokizumab open-label
11 An Efficacy and Safety Study of Gevokizumab in Treating Active Ulcers of Pyoderma Gangrenosum Terminated NCT02315417 Phase 3 gevokizumab;Placebo;gevokizumab open-label
12 A 2-Year, Open-Label, Safety Extension Study of Gevokizumab in Subjects With Pyoderma Gangrenosum Terminated NCT02318914 Phase 3 gevokizumab
13 Proof of Concept Study of Gevokizumab in the Treatment of Pyoderma Gangrenosum Completed NCT01882504 Phase 2 gevokizumab
14 A Phase II Open Label Study of Xilonix in Subjects With Pyoderma Gangrenosum Completed NCT01965613 Phase 2
15 Canakinumab for Pyoderma Gangrenosum Completed NCT01302795 Phase 2 Canakinumab
16 Study Comparing the Safety and Efficacy of 0.5% Ivermectin Cream to Placebo in Lice Infested Subjects Completed NCT00994422 Phase 2 Ivermectin cream;vehicle control
17 Topical Tacrolimus 0.1% Ointment For Treatment Of Cutaneous Crohn's Disease Completed NCT01233570 Phase 2 Tacrolimus
18 Effect of GSK1399686 in Patients With Mild to Moderately Active Ulcerative Colitis Completed NCT01036022 Phase 2 GSK1399686
19 An Open-Label, Proof-of-Concept Study of Ixekizumab in the Treatment of Pyoderma Gangrenosum Recruiting NCT03137160 Phase 2
20 Single-arm Study to Assess a Potential Effect of Anti-IL-17 (Secukinumab) in the Treatment of Pyoderma Gangrenosum Recruiting NCT02733094 Phase 1, Phase 2 Secukinumab
21 Efficacy and Safety of APD334 in Patients With Pyoderma Gangrenosum Recruiting NCT03072953 Phase 2 APD334
22 Efficacy, Safety and Tolerability of AIN457 in Moderate to Severe Active Crohn's Disease Terminated NCT00584740 Phase 2 AIN457;Placebo
23 Safety and Efficacy Study of Humira in Treatment of Pyoderma Gangrenosum Withdrawn NCT00730717 Phase 2 Humira;Humira
24 Study to Determine the Safety and Efficacy of Adalimumab in the Treatment of Pyoderma Gangrenosum Withdrawn NCT00690846 Phase 2 adalimumab
25 Open Label Study for Adults With Pyoderma Gangrenosum and Inflammatory Bowel Disease Completed NCT00791557 Not Applicable Infliximab
26 Prevalence of RHD, Pyoderma and Scabies in Children in Fiji Completed NCT00284843
27 Streptococcal Infections in Fiji - Prevalence of Group A Streptococcal Pyoderma and Scabies in Infants in Fiji Completed NCT00436891
28 Incidence of Group A Strep Pharyngitis in School Children in Fiji Completed NCT00284882
29 Evaluation of a Regional Healthy Skin Program in Remote Aboriginal Communities of Australia's Northern Territory Completed NCT00884728
30 Special Drug Use Investigation for CLAVAMOX® (Amoxicillin/Clavulanate) Pediatrics Dry Syrup (Every Indication Excluded Otitis Media) Completed NCT01406275 Amoxicillin and clavulanate
31 Schnitzler Syndrome: Clinical Study, Physiopathological and Search for Genetic Factors Completed NCT00933296
32 Observational Study of the Genetic Architecture of Neutrophil-Mediated Inflammatory Skin Diseases Recruiting NCT01952275
33 A Real World, Observational Registry of Chronic Wounds and Ulcers Recruiting NCT02280733
34 Entyvio (Vedolizumab) Long Term Safety Study Recruiting NCT02674308 Vedolizumab
35 Prospective Observational Study on Ustekinumab (Stelara) Assessing Efficacy and Healthcare Resource Utilization in Crohn's Disease Recruiting NCT03495973 Ustekinumab
36 Tele-dermatology of Skin Cancer in a Cohort of Local Health Authority Employees in the Province of Bergamo Active, not recruiting NCT02902822 Not Applicable
37 Certolizumab Pegol for the Treatment of Patients With Active Rheumatoid Arthritis (RA) and Crohn's Disease (CD) Terminated NCT01577264

Search NIH Clinical Center for Pyoderma

Cochrane evidence based reviews: pyoderma

Sources

Genetic Tests for Pyoderma

About this section
Sources

Anatomical Context for Pyoderma

About this section

MalaCards organs/tissues related to Pyoderma:

41
Skin, Neutrophil, Lung, T Cells, Liver, Myeloid, Bone
Sources

Publications for Pyoderma

About this section

Articles related to Pyoderma:

(show top 50) (show all 931)
# Title Authors Year
1
Pyoderma gangrenosum: a review of pathogenesis and treatment. ( 29406827 )
2018
2
Pyoderma gangrenosum in the genital area: successful treatment using adalimumab. ( 29378677 )
2018
3
A case of chronic ulcer due to subcutaneous arteriolosclerosis in an obese patient mimicking pyoderma gangrenosum. ( 29887980 )
2018
4
Skin Grafting in Pyoderma Gangrenosum. ( 29896322 )
2018
5
The PARACELSUS score: A novel diagnostic tool for pyoderma gangrenosum. ( 29388188 )
2018
6
Pulmonary nodules and nodular scleritis in a teenager with superficial granulomatous pyoderma gangrenosum. ( 29243307 )
2018
7
A Case of Pyoderma Gangrenosum with Myelodysplastic Syndrome. ( 29853768 )
2018
8
Erythema elevatum diutinum associated with severe oropharyngeal ulceration and pyoderma gangrenosum. ( 29750453 )
2018
9
Case of infective endocarditis caused by implanted artificial hair pyoderma. ( 29923626 )
2018
10
Endovenous Treatment of Varicose Veins in Patients With Pyoderma Gangrenosum. ( 29933301 )
2018
11
Epidemiology of pyoderma gangrenosum: Results from an Italian prospective multicentre study. ( 29877043 )
2018
12
Pyoderma Gangrenosum of the Preauricular Area with Ulcerative Colitis: A Case Report and Review. ( 29890815 )
2018
13
Pyoderma gangrenosum with its subtype affecting oral mucosa pyostomatitis vegetans following skin melanoma surgical excision in a patient with ulcerative colitis: a case report. ( 29760625 )
2018
14
A Case of Pyoderma Gangrenosum Misdiagnosed as Necrotizing Infection: A Potential Diagnostic Catastrophe. ( 29854503 )
2018
15
A systematic review of pyoderma gangrenosum with pulmonmary involvement: clinical presentation, diagnosis, and management. ( 29377399 )
2018
16
Pyogenic arthritis pyoderma gangrenosum and acne syndrome: A rare but important diagnosis for antibiotic-resistant erysipelas-like erythema and osteonecrosis. ( 29943877 )
2018
17
Blastomycosis-like Pyoderma Arising in Lichen Planus. ( 29462233 )
2018
18
Management of Facial Pyoderma Gangrenosum Using Platelet-Rich Fibrin: A Technical Report. ( 29425752 )
2018
19
Case of pyoderma gangrenosum-like sporotrichosis caused by Sporothrix globosa in a patient with ulcerative colitis. ( 29488248 )
2018
20
Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum: A Delphi Consensus of International Experts. ( 29450466 )
2018
21
Successful treatment with ustekinumab and vacuum-assisted closure therapy in recalcitrant myelodysplastic syndrome-associated pyoderma gangrenosum: case report and literature review. ( 29851121 )
2018
22
A case of neutrophilic dermatoses including pyoderma gangrenosum as a continuous disease spectrum to SAPHO syndrome. ( 29756300 )
2018
23
Pyoderma Gangrenosum of the Breast After Mastopexy. ( 29847306 )
2018
24
Pyoderma Gangranosum-Like Blastomycosis. ( 29486592 )
2018
25
Cutaneous Diphtheria Mimicking Pyoderma Gangrenosum. ( 29282460 )
2018
26
Successful therapy of Pyoderma gangrenosum with a JAK2 inhibitor. ( 29451690 )
2018
27
Pyoderma Gangrenosum Under Dabrafenib and Trametinib for Metastatic Melanoma. ( 29362816 )
2018
28
Erratum: Blastomycosis-like pyoderma: Novel use of potassium iodide. ( 29923506 )
2018
29
A case of pyoderma gangrenosum, acne, hidradenitis suppurativa (PASH) syndrome associated with diabetes mellitus type 1 treated with adalimumab. ( 29368847 )
2018
30
Paraneoplastic Pyoderma Gangrenosum Associated with Rectal Adenocarcinoma. ( 29386837 )
2018
31
The rapidly evolving lesions of ulcerative pyoderma gangrenosum: a timeline. ( 29806128 )
2018
32
Recurrent pyoderma gangrenosum developed after a cesarean section with a 10-year interval. ( 29920658 )
2018
33
<i>LPIN2</i> gene mutation in a patient with overlapping neutrophilic disease (pyoderma gangrenosum and aseptic abscess syndrome). ( 29387759 )
2018
34
The Validity of the Diagnostic Code for Pyoderma Gangrenosum in an Electronic Database. ( 29451671 )
2018
35
Cocaine-induced pyoderma gangrenosum-like lesions. ( 29786948 )
2018
36
Hyperbaric oxygen therapy for pyoderma gangrenosum associated with ulcerative colitis. ( 29422812 )
2018
37
Central retinal arterial occlusion in a patient with pyoderma gangrenosum. ( 29941761 )
2018
38
Two cases of bullous pyoderma gangrenosum complicated by Epstein-Barr virus infection. ( 29952293 )
2018
39
Recurrent pyoderma and its underlying primary diseases: a retrospective evaluation of 157 dogs. ( 29419485 )
2018
40
Dental treatment of a rare case of pyoderma gangrenosum with aggressive periodontal disease. ( 29945713 )
2018
41
The impact of underlying disease state on outcomes in patients with pyoderma gangrenosum: A national survey. ( 29438762 )
2018
42
Pyoderma Gangrenosum: A Review for the Gastroenterologist. ( 29788368 )
2018
43
Usefulness of metagenomic analysis in differential diagnosis for pyoderma gangrenosum. ( 29936877 )
2018
44
Pyoderma Gangrenosum Secondary to Severe Congenital Neutropenia. ( 29707446 )
2018
45
Erythema elevatum diutinum verbunden mit schwerer oropharyngealer Ulzeration und Pyoderma gangraenosum. ( 29750450 )
2018
46
Pyoderma gangrenosum-like ulceration of the lower extremity secondary to sunitinib therapy: a case report. ( 29977559 )
2018
47
Pyoderma gangraenosum-Aohnliche LAosionen durch Kokain. ( 29873911 )
2018
48
Cogan's syndrome with pyoderma gangrenosum: management of two uncommon disorders with aggressive presentation in a patient. ( 29925554 )
2018
49
Diagnosis uPGrade-Advances in Pyoderma Gangrenosum. ( 29450448 )
2018
50
Retiform hemangioendothelioma presenting as a pedunculated nodule on the site of an inguinal pyoderma chronica. ( 29756229 )
2018
Sources

Variations for Pyoderma

About this section
Sources

Expression for Pyoderma

About this section
Search GEO for disease gene expression data for Pyoderma.
Sources

Pathways for Pyoderma

About this section

Pathways related to Pyoderma according to GeneCards Suite gene sharing:

(show all 26)
# Super pathways Score Top Affiliating Genes
1
TGF-Beta Pathway 64
Show member pathways
 13.32 BTK CXCL8 IFNA2 IL1R1 ITGB2 TNF
2
Innate Immune System 66
Show member pathways
 13.29 BTK CXCL8 DSG1 IFNA2 IL1R1 ITGB2
3
Cytokine Signaling in Immune system 66
Show member pathways
 13.06 CXCL8 IFNA2 IL1R1 ITGB2 MMP1 NOD2
4
Toll Comparative Pathway 64
Show member pathways
 12.1 CXCL8 IL1R1 TNF
5
Bacterial infections in CF airways 22
Show member pathways
 12.02 CXCL8 IL1R1 TNF
6
Toll-like Receptor Signaling Pathway 37 1
Show member pathways
 12.02 BTK CXCL8 IFNA2 MEFV NOD2 PSTPIP1
7
Tuberculosis 37
12.01 IFNA2 ITGB2 NOD2 TNF
8
IL-1 Family Signaling Pathways 65
Show member pathways
 11.98 CXCL8 IL1R1 IL36RN TNF
9
Hepatitis C 37
11.88 CXCL8 IFNA2 TNF
10
Osteoclast differentiation 37
11.87 BTK IL1R1 TNF
11
Spinal Cord Injury 1
11.83 CXCL8 IL1R1 TNF
12
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways 66
Show member pathways
 11.8 MEFV NOD2 PSTPIP1
13
Matrix Metalloproteinases 1
Show member pathways
 11.73 MMP1 MMP10 TNF
14
Interleukin-4 and 13 signaling 66
11.73 CXCL8 ITGB2 MMP1 TNF
15
Pertussis 37
11.6 CXCL8 ITGB2 TNF
16
Amoebiasis 37
11.6 CXCL8 IL1R1 ITGB2 TNF
17
NF-kappa B signaling pathway 37
11.54 BTK CXCL8 IL1R1 TNF
18
Photodynamic therapy-induced NF-kB survival signaling 1
Show member pathways
 11.51 CXCL8 MMP1 TNF
19
Cell adhesion_ECM remodeling 22
11.49 CXCL8 MMP1 MMP10
20
Legionellosis 37
11.43 CXCL8 ITGB2 TNF
21
Rheumatoid arthritis 37
11.41 CXCL8 ITGB2 MMP1 TNF
22
Interleukin-10 signaling 66
11.36 CXCL8 IL1R1 TNF
23
Malaria 37
11.34 CXCL8 ITGB2 TNF
24
EBV LMP1 signaling 1
11 CXCL8 TNF
25
Canonical NF-kappaB pathway 1
10.97 NOD2 TNF
26
Overview of nanoparticle effects 1
10.88 CXCL8 TNF
Sources

GO Terms for Pyoderma

About this section

Cellular components related to Pyoderma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.17 CXCL8 IFNA2 IL1R1 IL36RN MMP1 MMP10

Biological processes related to Pyoderma according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 immune response GO:0006955 9.83 CXCL8 IL1R1 IL36RN TNF
2 immune system process GO:0002376 9.8 BTK IL36RN MEFV NOD2 PSTPIP1
3 regulation of signaling receptor activity GO:0010469 9.78 CXCL8 IFNA2 IL36RN TNF
4 innate immune response GO:0045087 9.63 BTK IFNA2 IL36RN MEFV NOD2 PSTPIP1
5 defense response GO:0006952 9.62 CXCL8 IFNA2 NOD2 TNF
6 regulation of inflammatory response GO:0050727 9.61 IL1R1 NOD2 TNF
7 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.56 BTK ITGB2 NOD2 TNF
8 positive regulation of interleukin-8 production GO:0032757 9.51 NOD2 TNF
9 cytokine-mediated signaling pathway GO:0019221 9.5 CXCL8 IFNA2 IL1R1 IL36RN ITGB2 MMP1
10 negative regulation of interleukin-6 production GO:0032715 9.49 IL36RN TNF
11 embryonic digestive tract development GO:0048566 9.46 CXCL8 TNF
12 cellular extravasation GO:0045123 9.37 ITGB2 TNF
13 inflammatory response GO:0006954 9.23 CXCL8 IFNA2 IL36RN ITGB2 MEFV NOD2

Molecular functions related to Pyoderma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 CXCL8 IFNA2 IL36RN TNF
Sources

Sources for Pyoderma

About this section
3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Content
Loading form....