MCID: PYM002
MIFTS: 19

Pyometritis

Categories: Reproductive diseases

Aliases & Classifications for Pyometritis

MalaCards integrated aliases for Pyometritis:

Name: Pyometritis 12 15 70

Classifications:



External Ids:

Disease Ontology 12 DOID:0050862
UMLS 70 C0686163

Summaries for Pyometritis

Disease Ontology : 12 A uterine disease that is characterized by inflammation of the uterus and is associated with pus in the uterine cavity.

MalaCards based summary : Pyometritis is related to luminal breast carcinoma b and vallecula cancer. An important gene associated with Pyometritis is DNAJC1 (DnaJ Heat Shock Protein Family (Hsp40) Member C1). Affiliated tissues include uterus, and related phenotype is integument.

Wikipedia : 73 Pyometra or pyometritis is a uterine infection. Though it is most commonly known as a disease of the... more...

Related Diseases for Pyometritis

Diseases related to Pyometritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 44)
# Related Disease Score Top Affiliating Genes
1 luminal breast carcinoma b 10.1 TBX3 PGR
2 vallecula cancer 10.1 BMI1 AREG
3 mixed cell adenoma 10.1 GNRH1 AREG
4 juvenile nasopharyngeal angiofibroma 10.0 PGR BMI1
5 diffuse peritoneal leiomyomatosis 10.0 PGR GNRH1
6 peritoneal benign neoplasm 10.0 PGR GNRH1
7 premenstrual tension 10.0 PGR GNRH1
8 adenomyoma 10.0 PGR GNRH1
9 endometriosis of ovary 9.9 PGR GNRH1
10 vulvar benign neoplasm 9.9 PGR HP
11 ovarian endometrial cancer 9.9 PGR HP
12 priapism 9.9 HP GNRH1
13 lipid-rich breast carcinoma 9.9 PRL PGR
14 breast adenoma 9.8 PRL PGR
15 pituitary infarct 9.8 PRL GNRH1
16 mixed cerebral palsy 9.8 PRL GNRH1
17 intracystic papillary adenoma 9.8 PRL PGR
18 hypothalamic disease 9.8 PRL GNRH1
19 endometritis 9.8 PGR HP
20 pituitary apoplexy 9.8 PRL GNRH1
21 empty sella syndrome 9.8 PRL GNRH1
22 van maldergem syndrome 1 9.8 PRL GNRH1
23 steroid inherited metabolic disorder 9.8 PRL GNRH1
24 pelvic varices 9.8 PRL GNRH1
25 thoracic benign neoplasm 9.8 PRL PGR
26 breast benign neoplasm 9.8 PRL PGR
27 diabetes insipidus, neurohypophyseal 9.7 PRL GNRH1
28 melancholia 9.7 PRL HP
29 ovarian cyst 9.7 PRL GNRH1
30 vaginal discharge 9.7 PGR HP GNRH1
31 sebaceous gland disease 9.7 PRL GNRH1
32 endometrial disease 9.7 PGR HP GNRH1
33 endogenous depression 9.7 PRL GNRH1
34 sexual disorder 9.6 PRL GNRH1
35 estrogen excess 9.6 PRL PGR GNRH1
36 uterine benign neoplasm 9.6 PRL PGR GNRH1
37 reproductive organ benign neoplasm 9.6 PRL PGR GNRH1
38 adenomyosis 9.6 PRL PGR GNRH1
39 leydig cell tumor 9.6 PRL GNRH1
40 gynecomastia 9.6 PRL PGR GNRH1
41 amelogenesis imperfecta, type ig 9.6 PRL PGR GNRH1
42 amelogenesis imperfecta 9.6 PRL PGR GNRH1
43 anovulation 9.5 PRL HP GNRH1
44 ovarian disease 9.2 PRL PGR GNRH1

Graphical network of the top 20 diseases related to Pyometritis:



Diseases related to Pyometritis

Symptoms & Phenotypes for Pyometritis

MGI Mouse Phenotypes related to Pyometritis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.1 AREG GNRH1 LGI1 PGR PRL TBX3

Drugs & Therapeutics for Pyometritis

Search Clinical Trials , NIH Clinical Center for Pyometritis

Genetic Tests for Pyometritis

Anatomical Context for Pyometritis

MalaCards organs/tissues related to Pyometritis:

40
Uterus

Publications for Pyometritis

Articles related to Pyometritis:

(show all 18)
# Title Authors PMID Year
1
Genetic mapping of Eutr1, a locus controlling E2-induced pyometritis in the Brown Norway rat, to RNO5. 61
16284801 2005
2
Localization of Eutr2, a locus controlling susceptibility to DES-induced uterine inflammation and pyometritis, to RNO5 using a congenic rat strain. 61
16284802 2005
3
Microbiology and management of polymicrobial female genital tract infections in adolescents. 61
12459228 2002
4
Investigation of association between alpha-1 proteinase inhibitor haplotype and endometritis in the thoroughbred mare. 61
8575373 1994
5
Interrelationships between postpartum events, hormonal therapy, reproductive abnormalities and reproductive performance in dairy cows: a path analysis. 61
3899335 1985
6
Prostaglandin therapeutics in the bitch and queen. 61
6596937 1984
7
[Prolonged fever and latent tuberculous foci]. 61
6261383 1981
8
Synergism of diethylstilbestrol and radiation in mammary carcinogenesis in female F344 rats. 61
480380 1979
9
Dinoprost in pyometritis in the bitch. 61
556225 1979
10
Dinoprost in pyometritis in the bitch. 61
555123 1979
11
Clinical, morphologic, and clinicopathologic findings in Beagles treated for two years with melengestrol acetate. 61
596689 1977
12
A case of pyometritis in an East African de Brazza's monkey (Cercopithecus neglectus). 61
4630568 1972
13
Pyometritis in spayed cats. 61
5047568 1972
14
Pyometritis in spayed cats. 61
5073604 1972
15
Pyometritis in spayed cats. 61
5073599 1972
16
Pyometritis in a spayed cat. 61
5047565 1972
17
Renal calculus in association with pyometritis. 61
6067872 1967
18
[Clinical diagnosis of pyometritis in bitches]. 61
6013110 1966

Variations for Pyometritis

Expression for Pyometritis

Search GEO for disease gene expression data for Pyometritis.

Pathways for Pyometritis

GO Terms for Pyometritis

Biological processes related to Pyometritis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell-cell signaling GO:0007267 9.13 PGR GNRH1 AREG
2 mammary gland development GO:0030879 8.8 TBX3 PRL PGR

Sources for Pyometritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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