Aliases & Classifications for Pyromania

MalaCards integrated aliases for Pyromania:

Name: Pyromania 12 15
Firesetting Behavior 12 44 70
Pathological Firesetting 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12402
ICD9CM 34 312.33
MeSH 44 D005391
NCIt 50 C94334
SNOMED-CT 67 600009
ICD10 32 F63.1
UMLS 70 C0016142

Summaries for Pyromania

Disease Ontology : 12 An impulse control disorder that involves the uncontrollable impulse to repeatedly set fires with no obvious motive.

MalaCards based summary : Pyromania, also known as firesetting behavior, is related to kleptomania and personality disorder. An important gene associated with Pyromania is MAOA (Monoamine Oxidase A), and among its related pathways/superpathways are Activation of Nicotinic Acetylcholine Receptors and Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics. Affiliated tissues include temporal lobe, brain and skin.

Wikipedia : 73 Pyromania is an impulse control disorder in which individuals repeatedly fail to resist impulses to... more...

Related Diseases for Pyromania

Graphical network of the top 20 diseases related to Pyromania:



Diseases related to Pyromania

Symptoms & Phenotypes for Pyromania

Drugs & Therapeutics for Pyromania

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Double-Blind, Placebo-Controlled Study of Naltrexone in Pyromania Withdrawn NCT00467454 Phase 2 Naltrexone;Placebo

Search NIH Clinical Center for Pyromania

Cochrane evidence based reviews: firesetting behavior

Genetic Tests for Pyromania

Anatomical Context for Pyromania

MalaCards organs/tissues related to Pyromania:

40
Temporal Lobe, Brain, Skin

Publications for Pyromania

Articles related to Pyromania:

(show top 50) (show all 106)
# Title Authors PMID Year
1
Zebrafish models of impulsivity and impulse control disorders. 61
32619029 2020
2
Young-Onset Parkinson's Disease with Impulse Control Disorder Due to Novel Variants of F-Box Only Protein 7. 61
32894901 2020
3
Neuropsychiatric Aspects of Impulse Control Disorders. 61
32439020 2020
4
Trichotillomania comorbidity in a sample enriched for familial obsessive-compulsive disorder. 61
31518848 2019
5
Compulsive sexual behavior disorder in obsessive-compulsive disorder: Prevalence and associated comorbidity. 61
31079471 2019
6
Scales to assess impulsive and compulsive behaviors in Parkinson's disease: Critique and recommendations. 61
31136681 2019
7
A Potential Tension in DSM-5: The General Definition of Mental Disorder versus Some Specific Diagnostic Criteria. 61
29850842 2019
8
Pyromania in court: Legal insanity versus culpability in Western Europe and the Netherlands (1800-1950). 61
29853011 2018
9
Cognitive inflexibility in a young woman with pyromania. 61
29464963 2018
10
[ADH/D and impulsiveness: Prevalence of impulse control disorders and other comorbidities, in 81 adults with attention deficit/hyperactivity disorder (ADH/D)]. 61
26928277 2016
11
Specialist group therapy for psychological factors associated with firesetting: Evidence of a treatment effect from a non-randomized trial with male prisoners. 61
26248329 2015
12
[Arson and pyromania, update 2015]. 61
26591081 2015
13
A look at firesetting, arson, and pyromania. 61
25977346 2015
14
The relationship of DSM-IV pathological gambling to compulsive buying and other possible spectrum disorders: results from the Iowa PG family study. 61
25660732 2015
15
A Practical Guide to Assessing Adult Firesetters' Fire-Specific Treatment Needs Using the Four Factor Fire Scales. 61
26745683 2015
16
Phenomenology and treatment of behavioural addictions. 61
23756285 2013
17
[Gambling brain]. 61
23300105 2013
18
Association between problematic Internet use and impulse control disorders among Iranian university students. 61
22489545 2012
19
Is obsessive-compulsive disorder an anxiety disorder, and what, if any, are spectrum conditions? A family study perspective. 61
21733222 2012
20
Firesetting, arson, pyromania, and the forensic mental health expert. 61
22960918 2012
21
Pyromania associated with escitalopram in a child. 61
21823913 2011
22
Impulse control disorders in psychiatric inpatients. 61
21546096 2011
23
Impulse control disorder comorbidity among patients with bipolar I disorder. 61
21683175 2011
24
Creating a firestorm: a review of children who deliberately light fires. 61
21382537 2011
25
From stack-firing to pyromania: medico-legal concepts of insane arson in British, US and European contexts, c. 1800-1913. Part 2 . 61
21877418 2010
26
From stack-firing to pyromania: medico-legal concepts of insane arson in British, US and European contexts, c. 1800-1913. Part I. 61
21879685 2010
27
The Pictorial Fire Stroop: a measure of processing bias for fire-related stimuli. 61
19707868 2009
28
[Antiepileptic drugs in the control of the impulses disorders]. 61
19927233 2009
29
Volitional disorders: a proposal for DSM-V. 61
18609413 2009
30
Juvenile firesetting in Italy: relationship to aggression, psychopathology, personality, self-efficacy, and school functioning. 61
18301940 2008
31
Solar activity as a possible cause of large forest fires--a case study: analysis of the Portuguese forest fires. 61
18291443 2008
32
Clinical characteristics and psychiatric comorbidity of pyromania. 61
18052565 2007
33
Impulse-control disorders in adolescent psychiatric inpatients: co-occurring disorders and sex differences. 61
17960976 2007
34
[Internet addiction]. 61
17803171 2007
35
Gender differences amongst adult arsonists at psychiatric assessment. 61
17725237 2007
36
Epidemiologic and clinical updates on impulse control disorders: a critical review. 61
16960655 2006
37
The neurobiology of substance and behavioral addictions. 61
17146406 2006
38
Fire interest and antisociality as risk factors in the severity and persistence of juvenile firesetting. 61
16926615 2006
39
Impulsivity and compulsivity in patients with trichotillomania or skin picking compared with patients with obsessive-compulsive disorder. 61
16769303 2006
40
SPECT imaging and treatment of pyromania. 61
16848668 2006
41
Study of impulse control disorders among women presenting nicotine dependence. 61
24941141 2006
42
Looking for pyromania: characteristics of a consecutive sample of Finnish male criminals with histories of recidivist fire-setting between 1973 and 1993. 61
16351734 2005
43
Impulse control disorders in adult psychiatric inpatients. 61
16263865 2005
44
Response of pyromania to biological treatment in a homeless person. 61
18568106 2005
45
[On the psychiatric examination of fire-raisers]. 61
15991730 2005
46
A comparative study of the behavioral, personality, and fire history characteristics of residential and outpatient adolescents (ages 12-17) with firesetting behaviors. 61
16114596 2005
47
[Impulsivity and mental disorders]. 61
15793698 2005
48
Diagnostic of sexual perversions. 61
12834034 2003
49
[Pathological fire-setting (pyromania)]. 61
14503297 2003
50
Commentary: Models and correlates of firesetting behavior. 61
12817843 2003

Variations for Pyromania

Expression for Pyromania

Search GEO for disease gene expression data for Pyromania.

Pathways for Pyromania

GO Terms for Pyromania

Cellular components related to Pyromania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 acetylcholine-gated channel complex GO:0005892 8.62 CHRNA7 CHRNA1

Biological processes related to Pyromania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of membrane potential GO:0042391 9.37 CHRNA7 CHRNA1
2 excitatory postsynaptic potential GO:0060079 9.32 CHRNA7 CHRNA1
3 nervous system process GO:0050877 9.26 CHRNA7 CHRNA1
4 regulation of postsynaptic membrane potential GO:0060078 9.16 CHRNA7 CHRNA1
5 chemical synaptic transmission GO:0007268 9.13 HTR1B CHRNA7 CHRNA1
6 synaptic transmission, cholinergic GO:0007271 8.62 CHRNA7 CHRNA1

Molecular functions related to Pyromania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular ligand-gated ion channel activity GO:0005230 9.32 CHRNA7 CHRNA1
2 acetylcholine-gated cation-selective channel activity GO:0022848 9.26 CHRNA7 CHRNA1
3 acetylcholine receptor activity GO:0015464 9.16 CHRNA7 CHRNA1
4 acetylcholine binding GO:0042166 8.96 CHRNA7 CHRNA1
5 neurotransmitter receptor activity GO:0030594 8.8 HTR1B CHRNA7 CHRNA1

Sources for Pyromania

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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