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MCID: QDR001
MIFTS: 51

Quadriplegia

Categories: Neuronal diseases
Genes Tissues Related diseases Publications Pathways Symptoms & Phenotypes Drugs
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Aliases & Classifications for Quadriplegia

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MalaCards integrated aliases for Quadriplegia:

Name: Quadriplegia 12 77 15 17 74
Tetraplegia 12 30 15
Tetraplegias 56

Classifications:

MalaCards categories:
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 34


External Ids:

Disease Ontology 12 DOID:12835
ICD9CM 36 344.00
MeSH 45 D011782
NCIt 51 C50721
SNOMED-CT 69 11538006
ICD10 34 G82.5 G82.50
UMLS 74 C0034372
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Summaries for Quadriplegia

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MalaCards based summary : Quadriplegia, also known as tetraplegia, is related to spastic quadriplegia and pelizaeus-merzbacher disease, and has symptoms including muscle weakness, ophthalmoplegia and hemiplegia. An important gene associated with Quadriplegia is ELOVL4 (ELOVL Fatty Acid Elongase 4), and among its related pathways/superpathways is Carbon metabolism. The drugs Midodrine and Benzocaine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and heart, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 77 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury that results in the... more...

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Related Diseases for Quadriplegia

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Diseases related to Quadriplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 269)
# Related Disease Score Top Affiliating Genes
1 spastic quadriplegia 32.1 ELOVL4 PLP1 SDHA SDHD SLC16A2 SPTAN1
2 pelizaeus-merzbacher disease 31.9 PLP1 SLC16A2
3 mitochondrial complex ii deficiency 31.4 SDHA SDHD
4 spastic cerebral palsy 31.2 ALDH3A2 PLP1 WDR45B
5 ichthyosis, spastic quadriplegia, and mental retardation 12.6
6 neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures 12.5
7 microcephaly with spastic quadriplegia 12.1
8 spastic quadriplegia, retinitis pigmentosa, and mental retardation 12.1
9 absent eyebrows and eyelashes with mental retardation 11.6
10 paraplegia 11.4
11 sjogren-larsson syndrome 11.4
12 spinal cord injury 11.3
13 epileptic encephalopathy, early infantile, 5 11.3
14 leukodystrophy, hypomyelinating, 6 11.3
15 locked-in syndrome 11.2
16 alternating hemiplegia of childhood 1 11.1
17 alternating hemiplegia of childhood 2 11.1
18 epileptic encephalopathy, early infantile, 53 11.1
19 8p inverted duplication/deletion syndrome 11.1
20 oculocerebral syndrome with hypopigmentation 11.0
21 hsd10 mitochondrial disease 11.0
22 cortical dysplasia, complex, with other brain malformations 4 11.0
23 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 11.0
24 microcephaly, seizures, spasticity, and brain calcifications 11.0
25 spastic tetraplegia, thin corpus callosum, and progressive microcephaly 11.0
26 spastic tetraplegia-retinitis pigmentosa-intellectual disability syndrome 11.0
27 spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome 11.0
28 congenital ichthyosis-microcephalus-tetraplegia syndrome 11.0
29 inherited congenital spastic tetraplegia 11.0
30 porphyria variegata 11.0
31 argininemia 11.0
32 allan-herndon-dudley syndrome 11.0
33 epileptic encephalopathy, early infantile, 4 11.0
34 cerebral palsy, spastic quadriplegic, 2 11.0
35 encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum 11.0
36 immunodeficiency 49 11.0
37 encephalocele 11.0
38 familial glucocorticoid deficiency 11.0
39 spastic paraplegia 16 11.0
40 pelizaeus-merzbacher-like disease 10.1 PLP1 SLC16A2
41 kallmann syndrome with spastic paraplegia 10.1
42 mental retardation with spastic paraplegia and palmoplantar hyperkeratosis 10.1
43 epidural abscess 10.1
44 arthritis 10.1
45 cerebral palsy 10.1
46 spinal stenosis 10.1
47 spondylitis 10.1
48 meningitis 10.1
49 rheumatoid arthritis 10.0
50 scoliosis 10.0

Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to Quadriplegia
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Symptoms & Phenotypes for Quadriplegia

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UMLS symptoms related to Quadriplegia:


muscle weakness, ophthalmoplegia, hemiplegia, quadriparesis, other quadriplegia

MGI Mouse Phenotypes related to Quadriplegia:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.86 ALDH3A2 ARG1 ATP1A3 BCL11B ELOVL4 PIK3C2A
2 homeostasis/metabolism MP:0005376 9.85 ALDH3A2 ARG1 ATP1A3 BCL11B ELOVL4 PIK3C2A
3 mortality/aging MP:0010768 9.61 ARG1 ATP1A3 BCL11B ELOVL4 PIK3C2A PLP1
4 nervous system MP:0003631 9.23 ALDH3A2 ARG1 ATP1A3 ELOVL4 PLP1 SDHD
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Drugs & Therapeutics for Quadriplegia

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Drugs for Quadriplegia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 114)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Midodrine Approved Phase 4,Phase 2 133163-28-7, 42794-76-3 4195
2
Benzocaine Approved, Investigational Phase 4,Not Applicable 1994-09-7, 94-09-7 2337
3
tannic acid Approved Phase 4,Not Applicable 1401-55-4
4
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
5
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
6
Cefotaxime Approved Phase 4 63527-52-6 5742673 456256
7
Cefoxitin Approved Phase 4 35607-66-0 441199
8
Acetaminophen Approved Phase 4 103-90-2 1983
9
Baclofen Approved Phase 4 1134-47-0 2284
10
Melatonin Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 73-31-4 896
11 Adrenergic Agonists Phase 4,Phase 2,Phase 1,Not Applicable
12 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
13 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
14 Adrenergic Agents Phase 4,Phase 2,Phase 1,Not Applicable
15 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
16 Cholinergic Agents Phase 4,Phase 2,Phase 1,Not Applicable
17 Adrenergic alpha-Agonists Phase 4,Phase 2
18 Vasoconstrictor Agents Phase 4,Phase 2
19 Sympathomimetics Phase 4,Phase 2
20 Omega 3 Fatty Acid Phase 4
21 Protective Agents Phase 4,Phase 2,Phase 3,Phase 1
22 Antioxidants Phase 4,Phase 2,Phase 3,Phase 1
23 Central Nervous System Depressants Phase 4,Phase 1,Phase 2
24 Botulinum Toxins, Type A Phase 4
25 Acetylcholine Release Inhibitors Phase 4
26 abobotulinumtoxinA Phase 4
27 Neuromuscular Agents Phase 4
28 Botulinum Toxins Phase 4
29 Phosphodiesterase 5 Inhibitors Phase 4
30 Vasodilator Agents Phase 4,Phase 2,Phase 3
31 Phosphodiesterase Inhibitors Phase 4
32 Analgesics Phase 4,Phase 1,Phase 2
33 Analgesics, Non-Narcotic Phase 4,Phase 1,Phase 2
34 Anti-Infective Agents Phase 4
35 beta-Lactams Phase 4
36 Anti-Bacterial Agents Phase 4
37 Antipyretics Phase 4
38 Lactams Phase 4
39 Anesthetics Phase 4,Phase 1,Not Applicable
40 Anesthetics, General Phase 4
41
Nitric Oxide Approved Phase 2, Phase 3,Phase 3,Phase 1 10102-43-9 145068
42
Fenofibrate Approved Phase 2, Phase 3 49562-28-9 3339
43
4-Aminopyridine Approved Phase 3 504-24-5 1727
44
Nitroarginine Experimental, Investigational Phase 2, Phase 3,Phase 3 2149-70-4
45 Bronchodilator Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
46 Respiratory System Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
47 Anti-Asthmatic Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
48 Free Radical Scavengers Phase 2, Phase 3,Phase 3
49 NG-Nitroarginine Methyl Ester Phase 2, Phase 3,Phase 3
50 arginine Phase 2, Phase 3,Phase 3

Interventional clinical trials:

(show top 50) (show all 157)
# Name Status NCT ID Phase Drugs
1 Eyegaze Systems for Spinal Cord Injury: A Feasibility Study Unknown status NCT01943656 Phase 4
2 Body Temperature in Persons With Tetraplegia When Exposed to Cold Completed NCT01822535 Phase 4 Midodrine hydrochloride
3 Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels Completed NCT01896037 Phase 4
4 Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia Completed NCT00507546 Phase 4 Ramelteon;Placebo
5 Diaphragmatic Reinnervation of Tetraplegic Patients With Respiratory Insufficiency Completed NCT01350297 Phase 4
6 Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury. Completed NCT00320281 Phase 4 botulinum toxin A
7 Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males Completed NCT01067391 Phase 4 tadalafil;placebo
8 Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis Completed NCT01540838 Phase 4 Infusion with paracetamol;Bolus without paracetamol
9 Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia Recruiting NCT02379156 Phase 4 Midodrine Hydrochloride
10 Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity Recruiting NCT01579604 Phase 4
11 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Terminated NCT00752934 Phase 4 oral baclofen + placebo;placebo + oral baclofen
12 SCIPA (Spinal Cord Injury and Physical Activity) Hands-On: Early Intensive Hand Rehabilitation After Spinal Cord Injury Unknown status NCT01086930 Phase 3
13 Restoration of Upper Limb Function in Individuals With Sub-Acute Spinal Cord Injury Unknown status NCT01292811 Phase 3
14 Retraining Walking After Spinal Cord Injury Unknown status NCT00059553 Phase 2, Phase 3
15 Exhaled Levels of Nitric Oxide Completed NCT00753948 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
16 Prevention of Low Blood Pressure in Persons With Tetraplegia Completed NCT00237770 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
17 MEOPA to Improve Physical Therapy Results After Multilevel Surgery Completed NCT00632528 Phase 3 MEOPA;Medicinal air
18 In-home Telerehabilitation for Quadriplegic Hand Function Completed NCT00656149 Phase 2, Phase 3
19 Fenofibrate Treatment in SCI Completed NCT02455336 Phase 2, Phase 3 Fenofibrate
20 Combined Robotic Training and tDCS in Chronic SCI Recruiting NCT03555838 Phase 3
21 High Doses of 4-aminopyridine in Clinically Complete Chronic Spinal Cord Injury Patients. Not yet recruiting NCT03899584 Phase 3 4-Aminopyridine;Placebo oral capsule
22 Study of the Impact of the Use of a Corset on the Respiratory Function of Patients With Spinal Cord Injury Withdrawn NCT01569360 Phase 3
23 Cethrin in Acute Cervical Spinal Cord Injury Withdrawn NCT02053883 Phase 2, Phase 3 Cethrin (BA-210);Placebo
24 Spinal Cord Neuromodulation for SCI Unknown status NCT02313194 Phase 1, Phase 2
25 Surgical Management of Spinal Cord Injuries In Neck Unknown status NCT00475748 Phase 2
26 Safety and Efficacy of L-NAME and Midodrine to Increase MAP Completed NCT00835224 Phase 2 L-NAME;Midodrine;Placebo
27 FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI Completed NCT01208688 Phase 2
28 Dose Escalation Study of AST-OPC1 in Spinal Cord Injury Completed NCT02302157 Phase 1, Phase 2
29 A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries Completed NCT00500812 Phase 1, Phase 2 Cethrin
30 The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI) Completed NCT01349478 Phase 1, Phase 2
31 Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury Completed NCT01484184 Phase 1, Phase 2 SPINALON (buspirone + levodopa + cardidopa)
32 NISCI - Nogo Inhibition in Spinal Cord Injury Recruiting NCT03935321 Phase 2 NG-101;Placebos
33 [BrainConnexion] - Neurodevice Phase II Trial Recruiting NCT03811301 Phase 2
34 Olaparib With or Without Atezolizumab in Treating Patients With Locally Advanced or Metastatic Non-HER2-Positive Breast Cancer Recruiting NCT02849496 Phase 2 Atezolizumab;Olaparib
35 24hr Effects of Tiotropium Bromide in Tetraplegia Enrolling by invitation NCT02586649 Phase 2 Tiotropium Bromide;Placebo
36 Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries Suspended NCT00073853 Phase 2
37 Spinal Cord Injury Leg Rehabilitation Terminated NCT01498991 Phase 1, Phase 2
38 Cannabis for Spasticity in Multiple Sclerosis Terminated NCT00682929 Phase 1, Phase 2 Inhaled Cannabis;Oral THC;Oral Placebo;Inhaled placebo
39 Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury Withdrawn NCT01046175 Phase 2
40 Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI Unknown status NCT01355991 Phase 1 Tiotropium;Salmeterol
41 Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury Unknown status NCT01353599 Phase 1 Mometasone furoate
42 The Role of Melatonin in the Regulation of Blood Coagulation Completed NCT01741389 Phase 1 Melatonin ("Circadin")
43 Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis Completed NCT01124292 Phase 1
44 Use of Interactive Gaming for Enhanced Function After Spinal Cord Injury Completed NCT01537978 Phase 1
45 Improving Ambulatory Community Access After Paralysis Recruiting NCT01570816 Phase 1
46 The Safety of ahSC in Chronic SCI With Rehabilitation Active, not recruiting NCT02354625 Phase 1
47 Abdominal Functional Electrical Stimulation in Tetraplegia Unknown status NCT00202631 Not Applicable
48 Electrical Activation of The Diaphragm for Ventilatory Assist Unknown status NCT00010374 Not Applicable
49 Abdominal Functional Electrical Stimulation Training and Its Effect on Mechanical Insufflation-Exsufflation Unknown status NCT01800409 Not Applicable
50 UPNRIDE Powered Wheelchair for Individuals With Walking Impairment: Evaluation of Safety and Usability Unknown status NCT02983955 Not Applicable

Search NIH Clinical Center for Quadriplegia

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Genetic Tests for Quadriplegia

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Genetic tests related to Quadriplegia:

# Genetic test Affiliating Genes
1 Tetraplegia 30
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Anatomical Context for Quadriplegia

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MalaCards organs/tissues related to Quadriplegia:

42
Spinal Cord, Brain, Heart, Testes, Bone, Prostate, Tongue
Sources

Publications for Quadriplegia

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Articles related to Quadriplegia:

(show top 50) (show all 1403)
# Title Authors Year
1
What Causes Severe Myelopathy Resulting in Acute Quadriplegia after a Surgery for Atlantoaxial Subluxation due to Os Odontoideum? A Case Report. ( 31098350 )
2019
2
Tetraplegia associated with post-operative syringomyelia in spinal tuberculosis: a result of an epidural compartment syndrome? ( 30774988 )
2019
3
L5-S1 Charcot spine induced by diffuse idiopathic skeletal hyperostosis in chronic tetraplegia: 2 cases. ( 29920334 )
2019
4
Hyperhidrosis and Dysautonomia in a Patient with a History of Tetraplegia following Cervical Facet Radiofrequency Ablation: A Case Report. ( 30985080 )
2019
5
Positive airway pressure for sleep-disordered breathing in acute quadriplegia: a randomised controlled trial. ( 30538163 )
2019
6
Does auto-PAP work in patients with acute quadriplegia and sleep-disordered breathing? ( 30610154 )
2019
7
Acute-onset quadriplegia with hyperreflexia. ( 30624189 )
2019
8
Congenital deformation of the posterior arch of the atlas: Subluxation of the atlanto-axial joint with temporary quadriplegia. ( 30719304 )
2019
9
Large left posterior fossa meningioma presenting with quadriplegia in a woman with history of carbidopa-levodopa resistant parkinsonism. ( 30996844 )
2019
10
Correction: Experienced sitting-related problems and association with personal, lesion and wheelchair characteristics in persons with long-standing paraplegia and tetraplegia. ( 31073233 )
2019
11
Experienced sitting-related problems and association with personal, lesion and wheelchair characteristics in persons with long-standing paraplegia and tetraplegia. ( 30988398 )
2019
12
A High Definition Noninvasive Neuromuscular Electrical Stimulation System for Cortical Control of Combinatorial Rotary Hand Movements in a Human With Tetraplegia. ( 30106673 )
2019
13
The golden year: How functional recovery sets the stage for tendon transfer surgery among patients with tetraplegia-a qualitative analysis. ( 30172564 )
2019
14
Clinical efficacy of upper limb robotic therapy in people with tetraplegia: a pilot randomized controlled trial. ( 30206423 )
2019
15
Construction and evaluation of a model for wheelchair propulsion in an individual with tetraplegia. ( 30255235 )
2019
16
Effect of biceps-to-triceps transfer on rotator cuff stress during upper limb weight-bearing lift in tetraplegia: A modeling and simulation analysis. ( 31101433 )
2019
17
A Novel Pharyngeal Clearance Maneuver for Initial Tracheostomy Tube Cuff Deflation in High Cervical Tetraplegia. ( 30973517 )
2019
18
Clinically Significant Gains in Skillful Grasp Coordination by an Individual With Tetraplegia Using an Implanted Brain-Computer Interface With Forearm Transcutaneous Muscle Stimulation. ( 30902630 )
2019
19
Thoracoscopic intercostal to phrenic nerve transfer for diaphragmatic reanimation in a child with tetraplegia. ( 30883296 )
2019
20
Reorganization of muscle synergies in 2 individuals with C5 and C6 tetraplegia after biceps-triceps and posterior deltoid-triceps tendon transfers. ( 30798792 )
2019
21
Reach out and grasp the opportunity: reconstructive hand surgery in tetraplegia. ( 30744461 )
2019
22
Correction: Clinical efficacy of upper limb robotic therapy in people with tetraplegia: a pilot randomized controlled trial. ( 30718747 )
2019
23
Needs of individuals with tetraplegia and expectations regarding implanted neuroprosthesis. ( 30710636 )
2019
24
Rare Cause of Acute Tetraplegia and Respiratory Arrest: Cervicomedullary Neuroenteric Cyst in a Child: Case Report. ( 30701147 )
2019
25
Changes in Motor Evoked Potential Latency during Grasping after Tetraplegia. ( 30673355 )
2019
26
Worth the effort? Weighing up the benefit and burden of continuous positive airway pressure therapy for the treatment of obstructive sleep apnoea in chronic tetraplegia. ( 30356181 )
2019
27
Alternative scapular stabilization exercises to target strength, endurance and function of shoulders in tetraplegia: A prospective non-controlled intervention study. ( 29141513 )
2019
28
Team Approach: Treatment and Rehabilitation of Patients with Spinal Cord Injury Resulting in Tetraplegia. ( 30939498 )
2019
29
Breastfeeding Before and After Spinal Cord Injury: A Case Report of a Mother With C6 Tetraplegia. ( 31051097 )
2019
30
Development of acute promyelocytic leukemia in a patient with tetraplegia while in inpatient rehabilitation: A case report. ( 28929913 )
2018
31
Nonsurgical management of an extensive spontaneous spinal epidural hematoma causing quadriplegia and respiratory distress in a choledocholithiasis patient: A case report: Erratum. ( 29369212 )
2018
32
Acute Onset of Quadriplegia Secondary to Hypoparathyroidism: Mimicker of AMAN Variant of GBS. ( 29482695 )
2018
33
Effects of Walkbot gait training on kinematics, kinetics, and clinical gait function in paraplegia and quadriplegia. ( 29660947 )
2018
34
Clinical management of quadriplegia in low and middle-income countries: a patient's road to physiotherapy, prostheses and rehabilitation. ( 30054323 )
2018
35
The First Case Report of West Nile Virus-Induced Acute Flaccid Quadriplegia in Canada. ( 30123588 )
2018
36
Transient Anarthria and Quadriplegia in a Patient with Basilar Artery Hypoplasia and Coincidental Intracranial Lipoma: A Case Report. ( 30519181 )
2018
37
Hyper Acute Quadriplegia with Chronic Lead Toxicity; a Case Report. ( 30584560 )
2018
38
Chlorpyrifos-Induced Delayed Neurotoxicity with A Rare Presentation of Flaccid Quadriplegia: A Diagnostic Challenge. ( 30755975 )
2018
39
Energy expenditure after spinal cord injury in people with motor-complete tetraplegia or motor-complete paraplegia. ( 29238094 )
2018
40
Differences in Cortical Gray Matter Atrophy of Paraplegia and Tetraplegia after Complete Spinal Cord Injury. ( 30430910 )
2018
41
Intraspinal hypotension syndrome presents as transient quadriplegia. ( 27766904 )
2018
42
Variability Analysis on Gestures for People With Quadriplegia. ( 28113307 )
2018
43
WDR45B-related intellectual disability, spastic quadriplegia, epilepsy, and cerebral hypoplasia: A consistent neurodevelopmental syndrome. ( 28503735 )
2018
44
Quadriplegia post-coronary artery bypass graft surgery: an unusual case. ( 28823182 )
2018
45
Transient Hypokalemic Quadriplegia After a Lumbar Transforaminal Epidural Dexamethasone Injection: A Case Report. ( 29074369 )
2018
46
Magnetic resonance imaging of the upper airway in patients with quadriplegia and obstructive sleep apnea. ( 29082563 )
2018
47
A severe female case of arthrogryposis multiplex congenita with brain atrophy, spastic quadriplegia and intellectual disability caused by ZC4H2 mutation. ( 29254829 )
2018
48
Life-Threatening Hypokalemic Quadriplegia in a Postoperative Patient. ( 29482687 )
2018
49
Descriptive pilot study of vividness and temporal equivalence during motor imagery training after quadriplegia. ( 29944923 )
2018
50
Bronchodilator effects of ipratropium bromide and albuterol sulfate among subjects with tetraplegia. ( 27808011 )
2018
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Variations for Quadriplegia

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Expression for Quadriplegia

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Search GEO for disease gene expression data for Quadriplegia.
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Pathways for Quadriplegia

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Pathways related to Quadriplegia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Carbon metabolism 38
Show member pathways
 11.12 ARG1 SDHA SDHD
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GO Terms for Quadriplegia

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Cellular components related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.7 ALDH3A2 ATP1A3 ELOVL4 KANK1 PIK3C2A PLP1
2 extracellular vesicle GO:1903561 9.16 ATP1A3 SPTAN1
3 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 8.62 SDHA SDHD

Biological processes related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sphingolipid biosynthetic process GO:0030148 9.16 ALDH3A2 ELOVL4
2 tricarboxylic acid cycle GO:0006099 8.96 SDHA SDHD
3 mitochondrial electron transport, succinate to ubiquinone GO:0006121 8.62 SDHA SDHD

Molecular functions related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 succinate dehydrogenase (ubiquinone) activity GO:0008177 8.96 SDHA SDHD
2 succinate dehydrogenase activity GO:0000104 8.62 SDHA SDHD
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Sources for Quadriplegia

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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