Aliases & Classifications for Quadriplegia

MalaCards integrated aliases for Quadriplegia:

Name: Quadriplegia 12 76 15 73
Tetraplegia 12 29 15
Tetraplegias 55

Classifications:



External Ids:

Disease Ontology 12 DOID:12835
ICD10 33 G82.5 G82.50
ICD9CM 35 344.00
MeSH 44 D011782
NCIt 50 C50721
SNOMED-CT 68 11538006
UMLS 73 C0034372

Summaries for Quadriplegia

MalaCards based summary : Quadriplegia, also known as tetraplegia, is related to spastic quadriplegia and pelizaeus-merzbacher disease, and has symptoms including muscle weakness, hemiplegia and ophthalmoplegia. An important gene associated with Quadriplegia is ELOVL4 (ELOVL Fatty Acid Elongase 4), and among its related pathways/superpathways is Carbon metabolism. The drugs Benzocaine and tannic acid have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and heart, and related phenotypes are hematopoietic system and homeostasis/metabolism

Wikipedia : 76 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury that results in the... more...

Related Diseases for Quadriplegia

Diseases related to Quadriplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 240)
# Related Disease Score Top Affiliating Genes
1 spastic quadriplegia 32.7 ELOVL4 PLP1 SDHA SDHAF1 SDHD SLC16A2
2 pelizaeus-merzbacher disease 31.9 PLP1 SLC16A2
3 mitochondrial complex ii deficiency 31.4 SDHA SDHAF1 SDHD
4 spastic cerebral palsy 31.3 ALDH3A2 PLP1
5 ichthyosis, spastic quadriplegia, and mental retardation 12.4
6 neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures 12.3
7 microcephaly with spastic quadriplegia 12.1
8 spastic quadriplegia, retinitis pigmentosa, and mental retardation 12.0
9 congenital ichthyosis, microcephalus, quadriplegia 12.0
10 absent eyebrows and eyelashes with mental retardation 11.6
11 paraplegia 11.3
12 spinal cord injury 11.3
13 leukodystrophy, hypomyelinating, 6 11.2
14 locked-in syndrome 11.1
15 alternating hemiplegia of childhood 1 11.1
16 alternating hemiplegia of childhood 2 11.1
17 oculocerebral syndrome with hypopigmentation 11.0
18 sjogren-larsson syndrome 11.0
19 hsd10 mitochondrial disease 11.0
20 cortical dysplasia, complex, with other brain malformations 4 11.0
21 microcephaly, seizures, spasticity, and brain calcifications 11.0
22 spastic tetraplegia, thin corpus callosum, and progressive microcephaly 11.0
23 spastic tetraplegia-retinitis pigmentosa-intellectual disability syndrome 11.0
24 spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome 11.0
25 congenital ichthyosis-microcephalus-tetraplegia syndrome 11.0
26 inherited congenital spastic tetraplegia 11.0
27 porphyria variegata 10.9
28 argininemia 10.9
29 allan-herndon-dudley syndrome 10.9
30 cerebral palsy, spastic quadriplegic, 2 10.9
31 epileptic encephalopathy, early infantile, 5 10.9
32 encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum 10.9
33 immunodeficiency 49 10.9
34 epileptic encephalopathy, early infantile, 53 10.9
35 stxbp1 encephalopathy with epilepsy 10.9
36 encephalocele 10.9
37 familial glucocorticoid deficiency 10.9
38 neural crest tumor 10.1 SDHA SDHD
39 persistent generalized lymphadenopathy 10.1 SDHA SDHD
40 epidural abscess 10.1
41 carney triad 10.1 SDHA SDHD
42 mental retardation with spastic paraplegia and palmoplantar hyperkeratosis 10.1
43 spastic paraplegia 57, autosomal recessive 10.1
44 hereditary paraganglioma-pheochromocytoma syndromes 10.1 SDHA SDHD
45 pelizaeus-merzbacher-like disease 10.1 PLP1 SLC16A2
46 arthritis 10.1
47 cerebral palsy 10.1
48 spinal stenosis 10.1
49 spondylitis 10.1
50 meningitis 10.1

Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to Quadriplegia

Symptoms & Phenotypes for Quadriplegia

UMLS symptoms related to Quadriplegia:


muscle weakness, hemiplegia, ophthalmoplegia, quadriparesis, other quadriplegia

MGI Mouse Phenotypes related to Quadriplegia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.86 ALDH3A2 ARG1 ATP1A3 BCL11B ELOVL4 PIK3C2A
2 homeostasis/metabolism MP:0005376 9.85 ALDH3A2 ARG1 ATP1A3 BCL11B ELOVL4 PIK3C2A
3 mortality/aging MP:0010768 9.61 ARG1 ATP1A3 BCL11B ELOVL4 PIK3C2A PLP1
4 nervous system MP:0003631 9.28 ALDH3A2 ARG1 ATP1A3 ELOVL4 PIK3C2A PLP1

Drugs & Therapeutics for Quadriplegia

Drugs for Quadriplegia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 111)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Not Applicable 94-09-7, 1994-09-7 2337
2 tannic acid Approved Phase 4,Not Applicable
3
Midodrine Approved Phase 4,Phase 2 133163-28-7, 42794-76-3 4195
4
Acetylcholine Approved Phase 4 51-84-3 187
5
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
6
Cefoxitin Approved Phase 4 35607-66-0 441199
7
Acetaminophen Approved Phase 4 103-90-2 1983
8
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
9
Baclofen Approved Phase 4 1134-47-0 2284
10
Melatonin Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 73-31-4 896
11 Adrenergic Agents Phase 4,Phase 2,Phase 1,Not Applicable
12 Adrenergic Agonists Phase 4,Phase 2,Phase 1,Not Applicable
13 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
14 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
15 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
16 Cholinergic Agents Phase 4,Phase 2,Phase 1,Not Applicable
17 Adrenergic alpha-Agonists Phase 4,Phase 2
18 Sympathomimetics Phase 4,Phase 2
19 Vasoconstrictor Agents Phase 4,Phase 2
20 Omega 3 Fatty Acid Phase 4
21 Antioxidants Phase 4,Phase 2,Phase 3,Phase 1
22 Protective Agents Phase 4,Phase 2,Phase 3,Phase 1
23 Central Nervous System Depressants Phase 4,Phase 1,Phase 2
24 Neuromuscular Agents Phase 4
25 onabotulinumtoxinA Phase 4
26 abobotulinumtoxinA Phase 4
27 Acetylcholine Release Inhibitors Phase 4
28 Botulinum Toxins Phase 4
29 Botulinum Toxins, Type A Phase 4
30 Phosphodiesterase Inhibitors Phase 4
31 Vasodilator Agents Phase 4,Phase 2,Phase 3
32 Phosphodiesterase 5 Inhibitors Phase 4
33 Analgesics Phase 4,Phase 1,Phase 2
34 Analgesics, Non-Narcotic Phase 4,Phase 1,Phase 2
35 beta-Lactams Phase 4
36 Anti-Bacterial Agents Phase 4
37 Antipyretics Phase 4
38 Lactams Phase 4
39 Anti-Infective Agents Phase 4
40 Anesthetics Phase 4,Phase 1,Not Applicable
41 Anesthetics, General Phase 4
42
Nitric Oxide Approved Phase 2, Phase 3,Phase 3,Phase 1 10102-43-9 145068
43
Fenofibrate Approved Phase 2, Phase 3 49562-28-9 3339
44
Nitroarginine Experimental, Investigational Phase 2, Phase 3,Phase 3 2149-70-4
45 Bronchodilator Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
46 Anti-Asthmatic Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
47 Respiratory System Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
48 NG-Nitroarginine Methyl Ester Phase 2, Phase 3,Phase 3
49 arginine Phase 2, Phase 3,Phase 3
50 Free Radical Scavengers Phase 2, Phase 3,Phase 3

Interventional clinical trials:

(show top 50) (show all 151)
# Name Status NCT ID Phase Drugs
1 Eyegaze Systems for Spinal Cord Injury: A Feasibility Study Unknown status NCT01943656 Phase 4
2 Body Temperature in Persons With Tetraplegia When Exposed to Cold Completed NCT01822535 Phase 4 Midodrine hydrochloride
3 Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels Completed NCT01896037 Phase 4
4 Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia Completed NCT00507546 Phase 4 Ramelteon;Placebo
5 Diaphragmatic Reinnervation of Tetraplegic Patients With Respiratory Insufficiency Completed NCT01350297 Phase 4
6 Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury. Completed NCT00320281 Phase 4 botulinum toxin A
7 Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males Completed NCT01067391 Phase 4 tadalafil;placebo
8 Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis Completed NCT01540838 Phase 4 Infusion with paracetamol;Bolus without paracetamol
9 Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia Recruiting NCT02379156 Phase 4 Midodrine Hydrochloride
10 Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity Recruiting NCT01579604 Phase 4
11 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Terminated NCT00752934 Phase 4 oral baclofen + placebo;placebo + oral baclofen
12 SCIPA (Spinal Cord Injury and Physical Activity) Hands-On: Early Intensive Hand Rehabilitation After Spinal Cord Injury Unknown status NCT01086930 Phase 3
13 Restoration of Upper Limb Function in Individuals With Sub-Acute Spinal Cord Injury Unknown status NCT01292811 Phase 3
14 Retraining Walking After Spinal Cord Injury Unknown status NCT00059553 Phase 2, Phase 3
15 Exhaled Levels of Nitric Oxide Completed NCT00753948 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
16 Prevention of Low Blood Pressure in Persons With Tetraplegia Completed NCT00237770 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
17 MEOPA to Improve Physical Therapy Results After Multilevel Surgery Completed NCT00632528 Phase 3 MEOPA;Medicinal air
18 In-home Telerehabilitation for Quadriplegic Hand Function Completed NCT00656149 Phase 2, Phase 3
19 Fenofibrate Treatment in SCI Completed NCT02455336 Phase 2, Phase 3 Fenofibrate
20 Combined Robotic Training and tDCS in Chronic SCI Recruiting NCT03555838 Phase 3
21 Study of the Impact of the Use of a Corset on the Respiratory Function of Patients With Spinal Cord Injury Withdrawn NCT01569360 Phase 3
22 Cethrin in Acute Cervical Spinal Cord Injury Withdrawn NCT02053883 Phase 2, Phase 3 Cethrin (BA-210);Placebo
23 Spinal Cord Neuromodulation for SCI Unknown status NCT02313194 Phase 1, Phase 2
24 Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord Injury Unknown status NCT00833105 Phase 1, Phase 2
25 Surgical Management of Spinal Cord Injuries In Neck Unknown status NCT00475748 Phase 2
26 Safety and Efficacy of L-NAME and Midodrine to Increase MAP Completed NCT00835224 Phase 2 L-NAME;Midodrine;Placebo
27 Spinal Cord Injury Leg Rehabilitation Completed NCT01498991 Phase 1, Phase 2
28 FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI Completed NCT01208688 Phase 2
29 A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries Completed NCT00500812 Phase 1, Phase 2 Cethrin
30 The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI) Completed NCT01349478 Phase 1, Phase 2
31 Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury Completed NCT01484184 Phase 1, Phase 2 SPINALON (buspirone + levodopa + cardidopa)
32 [BrainConnexion] - Neurodevice Phase II Trial Recruiting NCT03811301 Phase 2
33 Olaparib With or Without Atezolizumab in Treating Patients With Locally Advanced or Metastatic Non-HER2-Positive Breast Cancer Recruiting NCT02849496 Phase 2 Atezolizumab;Olaparib
34 Dose Escalation Study of AST-OPC1 in Spinal Cord Injury Active, not recruiting NCT02302157 Phase 1, Phase 2
35 24hr Effects of Tiotropium Bromide in Tetraplegia Enrolling by invitation NCT02586649 Phase 2 Tiotropium Bromide;Placebo
36 Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries Suspended NCT00073853 Phase 2
37 Cannabis for Spasticity in Multiple Sclerosis Terminated NCT00682929 Phase 1, Phase 2 Inhaled Cannabis;Oral THC;Oral Placebo;Inhaled placebo
38 Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury Withdrawn NCT01046175 Phase 2
39 Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI Unknown status NCT01355991 Phase 1 Tiotropium;Salmeterol
40 Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury Unknown status NCT01353599 Phase 1 Mometasone furoate
41 The Role of Melatonin in the Regulation of Blood Coagulation Completed NCT01741389 Phase 1 Melatonin ("Circadin")
42 Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis Completed NCT01124292 Phase 1
43 Use of Interactive Gaming for Enhanced Function After Spinal Cord Injury Completed NCT01537978 Phase 1
44 The Safety of ahSC in Chronic SCI With Rehabilitation Recruiting NCT02354625 Phase 1
45 Improving Ambulatory Community Access After Paralysis Recruiting NCT01570816 Phase 1
46 Abdominal Functional Electrical Stimulation in Tetraplegia Unknown status NCT00202631 Not Applicable
47 Directing Neuroplasticity to Improve Rehabilitative Outcomes of the Upper Limb in Incomplete Quadriplegia Unknown status NCT01539109 Not Applicable
48 Electrical Activation of The Diaphragm for Ventilatory Assist Unknown status NCT00010374 Not Applicable
49 Abdominal Functional Electrical Stimulation Training and Its Effect on Mechanical Insufflation-Exsufflation Unknown status NCT01800409 Not Applicable
50 UPNRIDE Powered Wheelchair for Individuals With Walking Impairment: Evaluation of Safety and Usability Unknown status NCT02983955 Not Applicable

Search NIH Clinical Center for Quadriplegia

Genetic Tests for Quadriplegia

Genetic tests related to Quadriplegia:

# Genetic test Affiliating Genes
1 Tetraplegia 29

Anatomical Context for Quadriplegia

MalaCards organs/tissues related to Quadriplegia:

41
Spinal Cord, Brain, Heart, Bone, Testes, Tongue, Prostate

Publications for Quadriplegia

Articles related to Quadriplegia:

(show top 50) (show all 1329)
# Title Authors Year
1
Life-Threatening Hypokalemic Quadriplegia in a Postoperative Patient. ( 29482687 )
2018
2
Descriptive pilot study of vividness and temporal equivalence during motor imagery training after quadriplegia. ( 29944923 )
2018
3
Acute Onset of Quadriplegia Secondary to Hypoparathyroidism: Mimicker of AMAN Variant of GBS. ( 29482695 )
2018
4
Nonsurgical management of an extensive spontaneous spinal epidural hematoma causing quadriplegia and respiratory distress in a choledocholithiasis patient: A case report: Erratum. ( 29369212 )
2018
5
Effects of Walkbot gait training on kinematics, kinetics, and clinical gait function in paraplegia and quadriplegia. ( 29660947 )
2018
6
Development of acute promyelocytic leukemia in a patient with tetraplegia while in inpatient rehabilitation: A case report. ( 28929913 )
2018
7
Differences in Cortical Gray Matter Atrophy of Paraplegia and Tetraplegia after Complete Spinal Cord Injury. ( 30430910 )
2018
8
Energy expenditure after spinal cord injury in people with motor-complete tetraplegia or motor-complete paraplegia. ( 29238094 )
2018
9
Clinical management of quadriplegia in low and middle-income countries: a patient's road to physiotherapy, prostheses and rehabilitation. ( 30054323 )
2018
10
The First Case Report of West Nile Virus-Induced Acute Flaccid Quadriplegia in Canada. ( 30123588 )
2018
11
Transient Anarthria and Quadriplegia in a Patient with Basilar Artery Hypoplasia and Coincidental Intracranial Lipoma: A Case Report. ( 30519181 )
2018
12
Positive airway pressure for sleep-disordered breathing in acute quadriplegia: a randomised controlled trial. ( 30538163 )
2018
13
Bronchodilator effects of ipratropium bromide and albuterol sulfate among subjects with tetraplegia. ( 27808011 )
2018
14
A Novel EMG Interface for Individuals With Tetraplegia to Pilot Robot Hand Grasping. ( 28113511 )
2018
15
Double nerve transfer for restoration of hand grasp and release in C7 tetraplegia following complete cervical spinal cord injury. ( 30218162 )
2018
16
Energy Expenditure as a Function of Activity Level After Spinal Cord Injury: The Need for Tetraplegia-Specific Energy Balance Guidelines. ( 30283348 )
2018
17
Periodic limb movements in tetraplegia. ( 28464758 )
2018
18
Leveraging the Medical Context to Increase Upper Extremity Reconstruction Among Patients With Tetraplegia: A Qualitative Analysis. ( 28782539 )
2018
19
Transcranial direct current stimulation (tDCS) paired with massed practice training to promote adaptive plasticity and motor recovery in chronic incomplete tetraplegia: A pilot study. ( 28784042 )
2018
20
The impact of a specialized spinal cord injury center as compared with non-specialized centers on the acute respiratory management of patients with complete tetraplegia: an observational study. ( 29138486 )
2018
21
Fatal innominate artery hemorrhage in a patient with tetraplegia: Case report and literature review. ( 29323630 )
2018
22
Electrical stimulation-a mapping system for hand dysfunction in tetraplegia. ( 29358674 )
2018
23
Rapid calibration of an intracortical brain-computer interface for people with tetraplegia. ( 29363625 )
2018
24
Acute tetraplegia following laryngotracheal reconstruction surgery. ( 29416908 )
2018
25
Adaptive motor cortex plasticity following grip reconstruction in individuals with tetraplegia. ( 29439365 )
2018
26
Evaluation of the graded redefined assessment of strength, sensibility and prehension (GRASSP) in children with tetraplegia. ( 29626193 )
2018
27
Persistent urine leakage around a suprapubic catheter: the experience of a person with chronic tetraplegia. ( 29644100 )
2018
28
Genioglossus reflex responses to negative upper airway pressure are altered in people with tetraplegia and obstructive sleep apnoea. ( 29658103 )
2018
29
A term vaginal delivery by a patient with traumatic tetraplegia: A case report. ( 29668610 )
2018
30
Dexterous Control of Seven Functional Hand Movements Using Cortically-Controlled Transcutaneous Muscle Stimulation in a Person With Tetraplegia. ( 29670506 )
2018
31
Diagnostic accuracy of a two-stage model for detecting obstructive sleep apnoea in chronic tetraplegia. ( 29735608 )
2018
32
Need and availability of assistive devices to compensate for impaired hand function of individuals with tetraplegia. ( 29863967 )
2018
33
Transcutaneous Electrical Spinal Stimulation Promotes Long-Term Recovery of Upper Extremity Function in Chronic Tetraplegia. ( 29877852 )
2018
34
Outcomes of reconstructive hand surgery in patients with tetraplegia and neuropathic pain. ( 29904187 )
2018
35
Effect of coil orientation on motor-evoked potentials in humans with tetraplegia. ( 29923194 )
2018
36
Normalization of disrupted clock gene expression in males with tetraplegia: a crossover randomized placebo-controlled trial of melatonin supplementation. ( 29985456 )
2018
37
Advanced Assessment of the Upper Limb in Tetraplegia: A Three-Tiered Approach to Characterizing Paralysis. ( 29997424 )
2018
38
Evaluation of the Capabilities of Upper Extremity Test (CUE-T) in Children With Tetraplegia. ( 29997427 )
2018
39
Management of Upper Extremities in Tetraplegia: Current Concepts. ( 30024421 )
2018
40
A High Definition Non-invasive Neuromuscular Electrical Stimulation System for Cortical Control of Combinatorial Rotary Hand Movements in a Human with Tetraplegia. ( 30106673 )
2018
41
The golden year: How functional recovery sets the stage for tendon transfer surgery among patients with tetraplegia-a qualitative analysis. ( 30172564 )
2018
42
Clinical efficacy of upper limb robotic therapy in people with tetraplegia: a pilot randomized controlled trial. ( 30206423 )
2018
43
Robust Closed-Loop Control of a Cursor in a Person with Tetraplegia using Gaussian Process Regression. ( 30216140 )
2018
44
Construction and evaluation of a model for wheelchair propulsion in an individual with tetraplegia. ( 30255235 )
2018
45
Combining robotic exoskeleton and body weight unweighing technology to promote walking activity in tetraplegia following SCI: A case study. ( 30335593 )
2018
46
Regional estimates of cortical thickness in brain areas involved in control of surgically restored limb movement in patients with tetraplegia. ( 30352011 )
2018
47
Worth the effort? Weighing up the benefit and burden of continuous positive airway pressure therapy for the treatment of obstructive sleep apnoea in chronic tetraplegia. ( 30356181 )
2018
48
Speaking Ability while Using an Inductive Tongue-Computer Interface for Individuals with Tetraplegia: Talking and Driving a Powered Wheelchair - a Case Study. ( 30440911 )
2018
49
Investigating Upper Limb Movement Classification on Users with Tetraplegia as a Possible Neuroprosthesis Interface. ( 30441476 )
2018
50
Generalised muscle weakness after bladder wall injection of Abobotulinum Toxin A: experience of a woman with tetraplegia who required increased caregiver support: importance of doctor-patient communication: duty of candour for spinal cord physician and responsibilities of a patient. ( 30455987 )
2018

Variations for Quadriplegia

Expression for Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for Quadriplegia

Pathways related to Quadriplegia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.12 ARG1 SDHA SDHD

GO Terms for Quadriplegia

Cellular components related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.7 ALDH3A2 ATP1A3 ELOVL4 KANK1 PIK3C2A PLP1
2 extracellular vesicle GO:1903561 9.16 ATP1A3 SPTAN1
3 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 8.62 SDHA SDHD

Biological processes related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sphingolipid biosynthetic process GO:0030148 9.16 ALDH3A2 ELOVL4
2 tricarboxylic acid cycle GO:0006099 8.96 SDHA SDHD
3 mitochondrial electron transport, succinate to ubiquinone GO:0006121 8.62 SDHA SDHD

Molecular functions related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 succinate dehydrogenase (ubiquinone) activity GO:0008177 8.96 SDHA SDHD
2 succinate dehydrogenase activity GO:0000104 8.62 SDHA SDHD

Sources for Quadriplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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