Aliases & Classifications for Quadriplegia

MalaCards integrated aliases for Quadriplegia:

Name: Quadriplegia 12 74 43 15 17 71
Tetraplegia 12 29 15
Tetraplegias 54

Classifications:



External Ids:

Disease Ontology 12 DOID:12835
ICD9CM 34 344.00
MeSH 43 D011782
NCIt 49 C50721
SNOMED-CT 67 11538006
ICD10 32 G82.5
UMLS 71 C0034372

Summaries for Quadriplegia

MalaCards based summary : Quadriplegia, also known as tetraplegia, is related to spastic quadriplegia and mitochondrial complex ii deficiency, and has symptoms including muscle weakness, ophthalmoplegia and hemiplegia. An important gene associated with Quadriplegia is ELOVL4 (ELOVL Fatty Acid Elongase 4), and among its related pathways/superpathways are Thyroid hormone signaling pathway and Proximal tubule bicarbonate reclamation. The drugs Acetylcholine and Tadalafil have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and testes, and related phenotypes are growth/size/body region and hematopoietic system

Wikipedia : 74 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury that results in the... more...

Related Diseases for Quadriplegia

Diseases related to Quadriplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 491)
# Related Disease Score Top Affiliating Genes
1 spastic quadriplegia 32.4 WDR45B TBCD SPTAN1 SLC16A2 SEC31A SDHD
2 mitochondrial complex ii deficiency 32.0 SDHD SDHAF1 SDHA
3 spastic cerebral palsy 32.0 SPTAN1 SLC16A2 PLP1 KANK1 ELOVL4 ALDH3A2
4 hereditary spastic paraplegia 29.6 SPTAN1 SLC16A2 PLP1 AP4E1 ALDH3A2
5 dystonia 29.4 SDHD SDHAF1 SDHA PLP1 ATP1A3
6 ichthyosis, spastic quadriplegia, and mental retardation 12.7
7 neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures 12.6
8 spastic tetraplegia and axial hypotonia, progressive 12.6
9 neurodevelopmental disorder with spastic quadriplegia, optic atrophy, seizures, and structural brain anomalies 12.5
10 spastic quadriplegia, retinitis pigmentosa, and mental retardation 12.2
11 microcephaly with spastic quadriplegia 12.2
12 absent eyebrows and eyelashes with mental retardation 11.7
13 spinal cord injury 11.5
14 inherited congenital spastic tetraplegia 11.5
15 paraplegia 11.5
16 epileptic encephalopathy, early infantile, 4 11.4
17 epileptic encephalopathy, early infantile, 5 11.4
18 leukodystrophy, hypomyelinating, 6 11.4
19 pelizaeus-merzbacher disease 11.4
20 spastic tetraplegia, thin corpus callosum, and progressive microcephaly 11.3
21 alternating hemiplegia of childhood 1 11.2
22 alternating hemiplegia of childhood 2 11.2
23 epileptic encephalopathy, early infantile, 53 11.2
24 8p inverted duplication/deletion syndrome 11.2
25 diencephalic-mesencephalic junction dysplasia syndrome 1 11.2
26 locked-in syndrome 11.2
27 spastic tetraplegia-retinitis pigmentosa-intellectual disability syndrome 11.2
28 congenital ichthyosis-microcephalus-tetraplegia syndrome 11.2
29 oculocerebral syndrome with hypopigmentation 11.2
30 hsd10 mitochondrial disease 11.2
31 cortical dysplasia, complex, with other brain malformations 4 11.2
32 diencephalic-mesencephalic junction dysplasia syndrome 2 11.2
33 epileptic encephalopathy, early infantile, 82 11.2
34 variegate porphyria 11.1
35 argininemia 11.1
36 farber lipogranulomatosis 11.1
37 sulfite oxidase deficiency, isolated 11.1
38 allan-herndon-dudley syndrome 11.1
39 cerebral palsy, spastic quadriplegic, 2 11.1
40 asparagine synthetase deficiency 11.1
41 encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum 11.1
42 immunodeficiency 49 11.1
43 epileptic encephalopathy, early infantile, 55 11.1
44 neurodevelopmental disorder with hypotonia, microcephaly, and seizures 11.1
45 familial glucocorticoid deficiency 11.1
46 rab18 deficiency 11.1
47 encephalocele 11.1
48 spastic paraplegia 16 11.1
49 pelizaeus-merzbacher-like disease 10.5 SLC16A2 PLP1
50 spinocerebellar ataxia, autosomal recessive 14 10.4 ELOVL4 ATP1A3

Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to Quadriplegia

Symptoms & Phenotypes for Quadriplegia

UMLS symptoms related to Quadriplegia:


muscle weakness, ophthalmoplegia, hemiplegia, quadriparesis, other quadriplegia

MGI Mouse Phenotypes related to Quadriplegia:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 growth/size/body region MP:0005378 10.07 AP4E1 ATP1A2 ATP1A3 BCL11B ELOVL4 MOG
2 hematopoietic system MP:0005397 9.9 ALDH3A2 AP4E1 ARG1 ATP1A3 BCL11B CCR6
3 homeostasis/metabolism MP:0005376 9.77 ALDH3A2 AP4E1 ARG1 ATP1A2 ATP1A3 BCL11B
4 nervous system MP:0003631 9.4 ALDH3A2 AP4E1 ARG1 ATP1A2 ATP1A3 CCR6

Drugs & Therapeutics for Quadriplegia

Drugs for Quadriplegia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 100)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Acetylcholine Approved, Investigational Phase 4 51-84-3 187
2
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
3
Midodrine Approved Phase 4 133163-28-7, 42794-76-3 4195
4
Norepinephrine Approved Phase 4 51-41-2 439260
5
Droxidopa Approved, Investigational Phase 4 23651-95-8 443940
6
Baclofen Approved Phase 4 1134-47-0 2284
7
Melatonin Approved, Nutraceutical, Vet_approved Phase 4 73-31-4 896
8 Anesthetics, General Phase 4
9 Omega 3 Fatty Acid Phase 4
10 Cholinergic Agents Phase 4
11 abobotulinumtoxinA Phase 4
12 Botulinum Toxins Phase 4
13 Botulinum Toxins, Type A Phase 4
14 Phosphodiesterase Inhibitors Phase 4
15 Phosphodiesterase 5 Inhibitors Phase 4
16 Vasodilator Agents Phase 4
17 Adrenergic alpha-Agonists Phase 4
18 Vasoconstrictor Agents Phase 4
19 Sympathomimetics Phase 4
20 Antihypertensive Agents Phase 4
21 Antiparkinson Agents Phase 4
22 Neurotransmitter Agents Phase 4
23 GABA Agonists Phase 4
24
Nitric Oxide Approved Phase 2, Phase 3 10102-43-9 145068
25
Fenofibrate Approved Phase 2, Phase 3 49562-28-9 3339
26
4-Aminopyridine Approved Phase 3 504-24-5 1727
27 NG-Nitroarginine Methyl Ester Phase 2, Phase 3
28 Lipid Regulating Agents Phase 2, Phase 3
29 Hypolipidemic Agents Phase 2, Phase 3
30 Antimetabolites Phase 2, Phase 3
31 Potassium Channel Blockers Phase 3
32
Arginine Investigational, Nutraceutical Phase 2, Phase 3 74-79-3 6322
33
Levodopa Approved Phase 1, Phase 2 59-92-7 6047
34
Dopamine Approved Phase 1, Phase 2 51-61-6, 62-31-7 681
35
Carbidopa Approved Phase 1, Phase 2 28860-95-9 34359
36
Buspirone Approved, Investigational Phase 1, Phase 2 36505-84-7 2477
37 Cholinergic Antagonists Phase 2
38 Parasympatholytics Phase 2
39 Tiotropium Bromide Phase 2 136310-93-5
40 Anticonvulsants Phase 2
41 Adrenergic Agents Phase 2
42 Adrenergic Agonists Phase 2
43 Serotonin Receptor Agonists Phase 1, Phase 2
44 Anti-Anxiety Agents Phase 1, Phase 2
45 Psychotropic Drugs Phase 1, Phase 2
46 Carbidopa, levodopa drug combination Phase 1, Phase 2
47 Dopamine Agents Phase 1, Phase 2
48 Immunoglobulins Phase 2
49 Antibodies Phase 2
50
Serotonin Investigational, Nutraceutical Phase 1, Phase 2 50-67-9 5202

Interventional clinical trials:

(show top 50) (show all 205)
# Name Status NCT ID Phase Drugs
1 Early Nerve Reconstruction Approach in Tetraplegic Patients With Dysfunctional Upper Extremity: a Randomized Controlled Trial. Unknown status NCT01579604 Phase 4
2 A Longitudinal Clinical Feasibility Study to Evaluate the Psychological and Functional Effects of Using the Tobii™ Eyegaze System by Inpatients With Tetraplegia Unknown status NCT01943656 Phase 4
3 Phrenic Reinnervation in Central Ventilatory Paralysis Due to Medullary Trauma With Phrenic Motoneuron Destruction Completed NCT01350297 Phase 4
4 Melatonin Replacement for Treatment of Sleep Disruption Completed NCT00507546 Phase 4 Ramelteon;Placebo
5 Omega-3 Supplementation to Increase HDL-c Levels in Those With Tetraplegia Completed NCT01896037 Phase 4
6 Core Temperature During Cold Exposure in Persons With Tetraplegia Completed NCT01822535 Phase 4 Midodrine hydrochloride
7 Botulinum Toxin A for the Treatment of Cervical/Shoulder Pain Following Acute Spinal Cord Injury. Completed NCT00320281 Phase 4 botulinum toxin A
8 A Randomized, Double-blind, Placebo-controlled Cross-over Trial Assessing the Effect of Tadalafil (Cialis) on the Cardiovascular System in Men With Complete Spinal Cord Injury (SCI) at or Above the Sixth Thoracic Level Completed NCT01067391 Phase 4 tadalafil;placebo
9 Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia Recruiting NCT02379156 Phase 4 Midodrine Hydrochloride
10 Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord Injury Recruiting NCT03602014 Phase 4 Northera
11 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Terminated NCT00752934 Phase 4 oral baclofen + placebo;placebo + oral baclofen
12 Restoration of Upper Limb Function in Individuals With Sub-Acute Spinal Cord Injury Unknown status NCT01292811 Phase 3
13 SCIPA (Spinal Cord Injury and Physical Activity) Hands-On: Early Intensive Hand Rehabilitation After Spinal Cord Injury Unknown status NCT01086930 Phase 3
14 Activity-Dependent Plasticity After Spinal Cord Injury Unknown status NCT00059553 Phase 2, Phase 3
15 Prevention of Low Blood Pressure in Persons With Tetraplegia Completed NCT00237770 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
16 The Effect of Nitric Oxide on Pulmonary Resistances and Blood Pressure in Persons With Tetraplegia Completed NCT00753948 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
17 Evaluation of the Efficacy of "MEOPA" Used to Obtain Better ROM Immediately After Multilevel Surgery in Children With Spastic Diplegia, Quadriplegia or Hemiplegia. Completed NCT00632528 Phase 3 MEOPA;Medicinal air
18 Outcome Evaluation of Exercise and Electrical Therapy for Quadriplegic Hand Function Completed NCT00656149 Phase 2, Phase 3
19 Improving Hand Function in Chronic SCI With Combined Robotic Training and tDCS Completed NCT03555838 Phase 3
20 Evaluation of Systemic Hypothermia Initiated After 6 Hours of Age in Infants ≥36 Weeks Gestation With Hypoxic-Ischemic Encephalopathy: A Bayesian Evaluation. A Protocol for the NICHD Neonatal Research Network Completed NCT00614744 Phase 2, Phase 3
21 An Open Label Safety and Efficacy Trial of Fenofibrate in Persons With SCI Completed NCT02455336 Phase 2, Phase 3 Fenofibrate
22 Quality of Life, Efficacy and Safety of High Doses of 4-aminopyridine in Patients With Clinically Complete Chronic Spinal Cord Injury: Multicenter, Randomized, Double Blind, Placebo Controlled Clinical Trial Not yet recruiting NCT03899584 Phase 3 4-Aminopyridine;Placebo oral capsule
23 Optimizing Cooling Strategies at < 6 Hours of Age for Neonatal Hypoxic-Ischemic Encephalopathy Terminated NCT01192776 Phase 3
24 A Phase II/III, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Assess the Efficacy and Safety of Cethrin in Subjects With Acute Cervical Spinal Cord Injury Withdrawn NCT02053883 Phase 2, Phase 3 Cethrin (BA-210);Placebo
25 Randomised Open Study of the Efficiency and Tolerance of the Use of a Corset on the Respiratory Function of Spinal Cord Injury Patients Withdrawn NCT01569360 Phase 3
26 A Randomized, Double-blind, Placebo-controlled Trial to Determine the Effects and Duration of Action of Tiotropium Bromide on Pulmonary Function in Persons With SCI Unknown status NCT02586649 Phase 2 Tiotropium Bromide;Placebo
27 ASIA Motor, Functional and Health Related Quality of Life Outcome in Traumatic Central Cord Syndrome, a Prospective Randomized Study Unknown status NCT00475748 Phase 2
28 A Phase 1/2a Dose Escalation Study of AST-OPC1 in Subjects With Subacute Cervical Spinal Cord Injury Completed NCT02302157 Phase 1, Phase 2
29 Safety and Efficacy of L-NAME and Midodrine to Increase MAP in Persons With Tetraplegia Completed NCT00835224 Phase 2 L-NAME;Midodrine;Placebo
30 A Phase I/IIa Dose-Ranging Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of BA-210 and the Neurological Status of Patients Following Administration of a Single Extradural Application of Cethrin During Surgery for Acute Thoracic and Cervical Spinal Cord Injury Completed NCT00500812 Phase 1, Phase 2 Cethrin
31 Electrical Stimulation Induced Lower Limb Exercise Capacity, Cardiorespiratory Response, Cardiovascular Risk Factors and Muscle Activity Patterns in Response to Robotic Assisted Treadmill Gait Training in Individuals With Complete Motor Spinal Cord Injury Completed NCT01349478 Phase 1, Phase 2
32 FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI Completed NCT01208688 Phase 2
33 Tri-therapy (SPINALON)-Elicited Spinal Locomotor Network Activation: Phase I-IIa Clinical Trial in Patients With Chronic Spinal Cord Injury Completed NCT01484184 Phase 1, Phase 2 SPINALON (buspirone + levodopa + cardidopa)
34 A Dose Response Trial Using 5 and 10 mg. of Midodrine Hydrochloride to Treat Orthostatic Hypotension in Persons With SCI Completed NCT00426842 Phase 2 Midodrine Hydrochloride
35 Neurodevice Phase II: Wireless Implantable Neurodevice Microsystem for Neuroprosthesis and Neuroscience Recruiting NCT03811301 Phase 2
36 Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury Recruiting NCT04041063 Phase 2
37 Enabling Forelimb Function With Agonist Drug and Epidural Stimulation in SCI Recruiting NCT02313194 Phase 1, Phase 2
38 Antibodies Against Nogo-A to Enhance Plasticity, Regeneration and Functional Recovery After Spinal Cord Injury - A Multicenter International Randomized Double Blind Placebo Controlled Phase II Clinical Proof of Concept Trial Recruiting NCT03935321 Phase 2 NG-101;Placebos
39 Exoskeleton Training After Spinal Cord Injury Recruiting NCT03410550 Phase 2
40 The Effect of Intrathecal Transplantation of Umbilical Cord Mesenchymal Stem Cells in Patients With Late Stage of Chronic Spinal Cord Injury:A Multicenter, Prospective, Cohort Study Recruiting NCT03505034 Phase 2 Umbilical Cord Mesenchymal Stem Cells
41 The Effect of Intrathecal Transplantation of Umbilical Cord Mesenchymal Stem Cells in Patients With Sub-Acute Spinal Cord Injury:A Multicenter, Randomized, Controlled Trial Recruiting NCT03521336 Phase 2 Umbilical Cord Mesenchymal Stem Cells;Placebo
42 The Effect of Intrathecal Transplantation of Umbilical Cord Mesenchymal Stem Cells in Patients With Early Stage of Chronic Spinal Cord Injury:A Multicenter, Randomized, Controlled Trial Recruiting NCT03521323 Phase 2 Umbilical Cord Mesenchymal Stem Cells;Placebos
43 A Phase II Multicenter, Randomized-Controlled Study to Evaluate the Safety and Efficacy of Autologous Incubated Macrophages for the Treatment of Patients With Complete Spinal Cord Injuries Suspended NCT00073853 Phase 2
44 Rehabilitation of the Lower Extremity With AMES Following Incomplete Spinal Cord Injury (SCI) Terminated NCT01498991 Phase 1, Phase 2
45 Effect of Two Different Air-stacking Techniques, Combined With Manually Assisted Cough, on Peak Cough Flow (PCF) in Patients With Acute Cervical or High Thoracic Spinal Cord Injury Withdrawn NCT01046175 Phase 2
46 Acute and Chronic Effects of an Anticholinergic Agent or a Long-Acting Beta 2 Agonist on Levels of Exhaled Nitric Oxide and Pulmonary Function in Persons With Tetraplegia Unknown status NCT01355991 Phase 1 Tiotropium;Salmeterol
47 Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury Unknown status NCT01353599 Phase 1 Mometasone furoate
48 The Role of Melatonin in the Regulation of Blood Coagulation Completed NCT01741389 Phase 1 Melatonin ("Circadin")
49 Use of Interactive Gaming After Spinal Cord Injury Completed NCT01537978 Phase 1
50 The Safety of Autologous Human Schwann Cells (ahSC) in Subjects With Chronic Spinal Cord Injury (SCI) Receiving Rehabilitation Completed NCT02354625 Phase 1

Search NIH Clinical Center for Quadriplegia

Cochrane evidence based reviews: quadriplegia

Genetic Tests for Quadriplegia

Genetic tests related to Quadriplegia:

# Genetic test Affiliating Genes
1 Tetraplegia 29

Anatomical Context for Quadriplegia

MalaCards organs/tissues related to Quadriplegia:

40
Spinal Cord, Brain, Testes, Bone, Heart, Tongue, Cortex

Publications for Quadriplegia

Articles related to Quadriplegia:

(show top 50) (show all 5760)
# Title Authors PMID Year
1
Sjögren-larsson syndrome: a study of clinical symptoms and dermatological treatment in 34 Swedish patients. 61 54
19197545 2009
2
[An autopsied case of schizophrenic patient who died from heat stroke]. 54 61
16780054 2006
3
[Clinical consequences of neuromuscular impairments in critically ill patients]. 54 61
16768037 2006
4
Adeno-associated virus vectors are able to restore fatty aldehyde dehydrogenase-deficiency. Implications for gene therapy in Sjogren-Larsson syndrome. 61 54
15834613 2005
5
Update on Sjögren-Larsson syndrome. 54 61
8884139 1996
6
[Etiological aspects of orthostatic hypotension]. 61 54
1344926 1992
7
Anterior Spinal Artery Syndrome: A Rare Precedented Reason of Postoperative Plegia After Spinal Deformity Surgery: A Report of Two Cases. 61
32502625 2020
8
Causes of, and countermeasures to, increased ventilatory drive in tetraplegia. 61
32329894 2020
9
Charcot in the ICU: functional tetraplegia after surgery. 61
32532808 2020
10
Lower Trapezius Muscle Transfer for Elbow Extension Reconstruction After Failed Nerve Transfer for Tetraplegia. 61
31585742 2020
11
Increased diaphragm motor unit discharge frequencies during quiet breathing in people with chronic tetraplegia. 61
32083718 2020
12
Impact of tetraplegia vs. paraplegia on venoarteriolar, myogenic and maximal cutaneous vasodilation responses of the microvasculature: Implications for cardiovascular disease. 61
32496962 2020
13
Quadriplegia and quadriparesis after endovascular aortic procedures: a catastrophic and under-reported complication? 61
32558527 2020
14
Acute Bilateral Internal Carotid Artery Occlusion Presenting With Symmetrical Cortical Infarctions Exhibits Dramatic Improvement After Mechanical Thrombectomy. 61
32544620 2020
15
Expanding the clinical and phenotypic heterogeneity associated with biallelic variants in ACO2. 61
32519519 2020
16
[A case of bilateral medial medullary and left tegmentum of pontine infarction in whom DSA-MR fusion imaging identified infarct-relevant arteries]. 61
32435047 2020
17
A novel compound heterozygous missense mutation in ASNS broadens the spectrum of asparagine synthetase deficiency. 61
32255274 2020
18
Cohort profile of the International Spinal Cord Injury (InSCI) Community Survey implemented in 22 countries. 61
32533933 2020
19
Bilateral cervical contusion spinal cord injury: A mouse model to evaluate sensorimotor function. 61
32561411 2020
20
A review of methods for achieving upper limb movement following spinal cord injury through hybrid muscle stimulation and robotic assistance. 61
32145251 2020
21
A Patient with Acute Cervical Cord Injury and COVID-19: A First Case Report. 61
32487972 2020
22
Using the Edinburgh Visual Gait Score to Compare Ankle-Foot Orthoses, Sensorimotor Orthoses and Barefoot Gait Pattern in Children with Cerebral Palsy. 61
32492892 2020
23
Robot-assisted gait training using a very small-sized Hybrid Assistive Limb® for pediatric cerebral palsy: A case report. 61
32249081 2020
24
Improving Grasp Function After Spinal Cord Injury With a Soft Robotic Glove. 61
32305931 2020
25
Factors associated with quality of life among mothers of children with cerebral palsy. 61
31981299 2020
26
Neural Cell Adhesion Molecule (NCAM) a Serum Biomarker Indicative for the Severity of Cervical Spondylotic Myelopathy. 61
32039991 2020
27
Selective neural electrical stimulation restores hand and forearm movements in individuals with complete tetraplegia. 61
32429963 2020
28
Inconclusive efficacy of intervention on upper-limb function after tetraplegia: A systematic review and meta-analysis. 61
31233828 2020
29
Nothing to lose: a phenomenological study of upper limb nerve transfer surgery for individuals with tetraplegia. 61
32356497 2020
30
Fabry disease presenting as bilateral medial medullary infarction with a "heart appearance" sign: a case report. 61
32397962 2020
31
Autoimmune glial fibillary acidic protein astrocytopathy associated meningoencephalomyelitis and bilateral sensorineuronal deafness. 61
31981881 2020
32
Acute rhabdomyolysis following viral infection with coxsackie A4 in a 50-day-old infant with Fukuyama congenital muscular dystrophy. 61
31983616 2020
33
Martsolf syndrome with novel mutation in the TBC1D20 gene in a family from Iran. 61
32162791 2020
34
Intramedullary cervical spinal cord teratoma. 61
32358400 2020
35
Functional independence of persons with long-standing motor complete spinal cord injury in the Netherlands. 61
30124386 2020
36
[Course of neurogenic bladder dysfunction in patients with spinal cord injury under homeopathic treatment]. 61
32424576 2020
37
The correlation between diffusion tensor imaging of the sacral cord and bladder contractility in people with tetraplegia. 61
32415223 2020
38
The Effect of High Dose Rate Interstitial Implant on Early and Locally Advanced Oral Cavity Cancers: Update and Long-Term Follow-Up Study. 61
32494525 2020
39
Tetraplegia after branched frozen elephant trunk implantation for acute type A aortic dissection. 61
32419257 2020
40
Ultrasound-guided platelet-rich plasma injection for the treatment of recalcitrant rotator cuff disease in wheelchair users with spinal cord injury: A pilot study. 61
32379581 2020
41
Clinical features of electric powered indoor/outdoor wheelchair users with spinal cord injuries: A cross-sectional study. 61
30036176 2020
42
Development of a skin temperature map for dermatomes in individuals with spinal cord injury: a cross-sectional study. 61
32371938 2020
43
Accidental injection of succinylcholine into epidural space as a test dose. 61
32317884 2020
44
Paralysis Caused by Spinal Cord Injury After Posterior Fossa Surgery: A Systematic Review. 61
32305599 2020
45
[Peripheral Nerve Disease]. 61
32284462 2020
46
Effects of MEG-based neurofeedback for hand rehabilitation after tetraplegia: preliminary findings in cortical modulations and grip strength. 61
32135525 2020
47
Responsiveness of the Motor Capacities Scale to upper limb reconstructive surgery in persons with tetraplegia due to cervical spinal cord injury. 61
32238864 2020
48
Hydrocephalus in Guillain barre syndrome: A case report and review of the literature. 61
32311917 2020
49
Exoskeletal-Assisted Walking During Acute Inpatient Rehabilitation Leads to Motor and Functional Improvement in Persons With Spinal Cord Injury: A Pilot Study. 61
31891715 2020
50
Effect of acetazolamide on susceptibility to central sleep apnea in chronic spinal cord injury. 61
32078469 2020

Variations for Quadriplegia

Expression for Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for Quadriplegia

Pathways related to Quadriplegia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.88 SLC16A2 ATP1A3 ATP1A2
2 10.32 ATP1A3 ATP1A2

GO Terms for Quadriplegia

Cellular components related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane GO:0016020 9.86 TBCD SPTAN1 SLC16A2 SEC31A SDHD SDHA
2 organelle membrane GO:0031090 9.43 ATP1A3 ATP1A2 ALDH3A2
3 sodium:potassium-exchanging ATPase complex GO:0005890 9.16 ATP1A3 ATP1A2
4 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone) GO:0005749 8.62 SDHD SDHA

Biological processes related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular sodium ion homeostasis GO:0006883 9.43 ATP1A3 ATP1A2
2 cell communication by electrical coupling involved in cardiac conduction GO:0086064 9.4 ATP1A3 ATP1A2
3 sodium ion export across plasma membrane GO:0036376 9.37 ATP1A3 ATP1A2
4 cellular potassium ion homeostasis GO:0030007 9.32 ATP1A3 ATP1A2
5 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.26 ATP1A3 ATP1A2
6 cellular response to steroid hormone stimulus GO:0071383 9.16 ATP1A3 ATP1A2
7 mitochondrial electron transport, succinate to ubiquinone GO:0006121 8.96 SDHD SDHA
8 response to glycoside GO:1903416 8.62 ATP1A3 ATP1A2

Molecular functions related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chaperone binding GO:0051087 9.5 TBCD ATP1A3 ATP1A2
2 sodium:potassium-exchanging ATPase activity GO:0005391 9.26 ATP1A3 ATP1A2
3 potassium-transporting ATPase activity GO:0008556 9.16 ATP1A3 ATP1A2
4 steroid hormone binding GO:1990239 8.96 ATP1A3 ATP1A2
5 succinate dehydrogenase activity GO:0000104 8.62 SDHD SDHA

Sources for Quadriplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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