Aliases & Classifications for Quadriplegia

MalaCards integrated aliases for Quadriplegia:

Name: Quadriplegia 12 76 15 73
Tetraplegia 12 29
Tetraplegias 55

Classifications:



External Ids:

Disease Ontology 12 DOID:12835
ICD10 33 G82.5 G82.50
ICD9CM 35 344.00
MeSH 44 D011782
NCIt 50 C50721
SNOMED-CT 68 11538006 155030003
UMLS 73 C0034372

Summaries for Quadriplegia

MalaCards based summary : Quadriplegia, also known as tetraplegia, is related to pelizaeus-merzbacher disease and spastic cerebral palsy, and has symptoms including hemiplegia, ophthalmoplegia and muscle weakness. An important gene associated with Quadriplegia is ELOVL4 (ELOVL Fatty Acid Elongase 4), and among its related pathways/superpathways are Mineral absorption and Endocrine and other factor-regulated calcium reabsorption. The drugs Benzocaine and Midodrine have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, brain and bone, and related phenotypes are homeostasis/metabolism and nervous system

Wikipedia : 76 Tetraplegia, also known as quadriplegia, is paralysis caused by illness or injury that results in the... more...

Related Diseases for Quadriplegia

Diseases related to Quadriplegia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 174)
# Related Disease Score Top Affiliating Genes
1 pelizaeus-merzbacher disease 31.7 PLP1 SLC16A2
2 spastic cerebral palsy 30.9 ALDH3A2 PLP1
3 hemiplegia 29.7 ATP1A2 ATP1A3
4 spastic quadriplegia 29.1 ARG1 BCL11B ELOVL4 KANK1 PLP1 SDHAF1
5 ichthyosis, spastic quadriplegia, and mental retardation 12.3
6 microcephaly with spastic quadriplegia 11.9
7 spastic quadriplegia, retinitis pigmentosa, and mental retardation 11.9
8 neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures 11.9
9 congenital ichthyosis, microcephalus, quadriplegia 11.8
10 absent eyebrows and eyelashes with mental retardation 11.4
11 paraplegia 11.2
12 spinal cord injury 11.2
13 locked-in syndrome 11.0
14 alternating hemiplegia of childhood 1 10.9
15 alternating hemiplegia of childhood 2 10.9
16 microcephaly, seizures, spasticity, and brain calcifications 10.8
17 spastic tetraplegia, thin corpus callosum, and progressive microcephaly 10.8
18 spastic tetraplegia-retinitis pigmentosa-intellectual disability syndrome 10.8
19 spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome 10.8
20 congenital ichthyosis-microcephalus-tetraplegia syndrome 10.8
21 inherited congenital spastic tetraplegia 10.8
22 porphyria variegata 10.8
23 argininemia 10.8
24 mitochondrial complex ii deficiency 10.8
25 allan-herndon-dudley syndrome 10.8
26 cerebral palsy, spastic quadriplegic, 2 10.8
27 epileptic encephalopathy, early infantile, 5 10.8
28 encephalopathy, progressive, early-onset, with brain atrophy and thin corpus callosum 10.8
29 immunodeficiency 49 10.8
30 epileptic encephalopathy, early infantile, 53 10.8
31 stxbp1 encephalopathy with epilepsy 10.8
32 encephalocele 10.8
33 familial glucocorticoid deficiency 10.8
34 cervicitis 10.5
35 spasticity 10.4
36 familial hemiplegic migraine 10.3 ATP1A2 ATP1A3
37 pelizaeus-merzbacher-like disease 10.3 PLP1 SLC16A2
38 hemiplegic migraine 10.2 ATP1A2 ATP1A3
39 cerebritis 10.0
40 epidural abscess 10.0
41 arthritis 9.9
42 cerebral palsy 9.9
43 spinal stenosis 9.9
44 meningitis 9.9
45 rheumatoid arthritis 9.9
46 aging 9.9
47 scoliosis 9.9
48 myopathy 9.9
49 hypokalemia 9.9
50 alacrima, achalasia, and mental retardation syndrome 9.8

Graphical network of the top 20 diseases related to Quadriplegia:



Diseases related to Quadriplegia

Symptoms & Phenotypes for Quadriplegia

UMLS symptoms related to Quadriplegia:


hemiplegia, ophthalmoplegia, muscle weakness, quadriparesis, other quadriplegia

MGI Mouse Phenotypes related to Quadriplegia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.61 ARG1 ATP1A2 ATP1A3 BCL11B ELOVL4 PIK3C2A
2 nervous system MP:0003631 9.28 ALDH3A2 ARG1 ATP1A2 ATP1A3 ELOVL4 PIK3C2A

Drugs & Therapeutics for Quadriplegia

Drugs for Quadriplegia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 107)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Benzocaine Approved, Investigational Phase 4,Not Applicable 1994-09-7, 94-09-7 2337
2
Midodrine Approved Phase 4,Phase 2 133163-28-7, 42794-76-3 4195
3
Baclofen Approved Phase 4 1134-47-0 2284
4
Acetylcholine Approved Phase 4 51-84-3 187
5
Tadalafil Approved, Investigational Phase 4 171596-29-5 110635
6
Acetaminophen Approved Phase 4 103-90-2 1983
7
Cefotaxime Approved Phase 4 63527-52-6 456256 5742673
8
Cefoxitin Approved Phase 4 35607-66-0 441199
9 tannic acid Approved, Nutraceutical Phase 4,Not Applicable
10
Melatonin Approved, Nutraceutical, Vet_approved Phase 4,Phase 1 73-31-4 896
11 Adrenergic Agents Phase 4,Phase 2,Phase 1,Not Applicable
12 Adrenergic Agonists Phase 4,Phase 2,Phase 1,Not Applicable
13 Adrenergic alpha-Agonists Phase 4,Phase 2
14 Autonomic Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
15 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
16 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
17 Vasoconstrictor Agents Phase 4,Phase 2
18 Cholinergic Agents Phase 4,Phase 2,Phase 1,Not Applicable
19 Antioxidants Phase 4,Phase 2,Phase 3,Phase 1
20 Central Nervous System Depressants Phase 4,Phase 1,Phase 2
21 Protective Agents Phase 4,Phase 2,Phase 3,Phase 1
22 abobotulinumtoxinA Phase 4
23 Botulinum Toxins Phase 4
24 Botulinum Toxins, Type A Phase 4
25 Neuromuscular Agents Phase 4
26 onabotulinumtoxinA Phase 4
27 Phosphodiesterase 5 Inhibitors Phase 4
28 Phosphodiesterase Inhibitors Phase 4
29 Vasodilator Agents Phase 4,Phase 2,Phase 3
30 Analgesics Phase 4,Phase 1,Phase 2
31 Analgesics, Non-Narcotic Phase 4,Phase 1,Phase 2
32 Anti-Bacterial Agents Phase 4
33 Anti-Infective Agents Phase 4
34 Antipyretics Phase 4
35 beta-Lactams Phase 4
36 Lactams Phase 4
37 Anesthetics Phase 4,Phase 1,Not Applicable
38 Anesthetics, General Phase 4
39 Omega 3 Fatty Acid Nutraceutical Phase 4
40
Nitric Oxide Approved Phase 2, Phase 3,Phase 3,Phase 1 10102-43-9 145068 160954
41
Menthol Approved Phase 2, Phase 3,Not Applicable 2216-51-5 16666
42
Fenofibrate Approved Phase 2, Phase 3 49562-28-9 3339
43 Anti-Asthmatic Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
44 Bronchodilator Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
45 Respiratory System Agents Phase 2, Phase 3,Phase 3,Phase 1,Not Applicable
46 Endothelium-Dependent Relaxing Factors Phase 2, Phase 3,Phase 3
47 NG-Nitroarginine Methyl Ester Phase 2, Phase 3,Phase 3
48 Fibrin Tissue Adhesive Phase 2, Phase 3,Phase 1
49 Hemostatics Phase 2, Phase 3,Phase 1
50 Antimetabolites Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 140)
# Name Status NCT ID Phase Drugs
1 Thermoregulation and Cognition During Cool Ambient Exposure in Tetraplegia Unknown status NCT02379156 Phase 4 Midodrine Hydrochloride
2 Eyegaze Systems for Spinal Cord Injury: A Feasibility Study Unknown status NCT01943656 Phase 4
3 Does Oral Baclofen Improve Care and Comfort in Spastic Children in Nursing Homes? Unknown status NCT00752934 Phase 4 oral baclofen + placebo;placebo + oral baclofen
4 Body Temperature in Persons With Tetraplegia When Exposed to Cold Completed NCT01822535 Phase 4 Midodrine hydrochloride
5 Omega-3 Supplementation for Tetraplegics With Poor Cholesterol Levels Completed NCT01896037 Phase 4
6 Functional Melatonin Replacement for Sleep Disruptions in Individuals With Tetraplegia Completed NCT00507546 Phase 4 Ramelteon;Placebo
7 Diaphragmatic Reinnervation of Tetraplegic Patients With Respiratory Insufficiency Completed NCT01350297 Phase 4
8 Investigating Botulinum Toxin A to Treat Acute Neck/Upper Shoulder Pain Following a New Spinal Cord Injury. Completed NCT00320281 Phase 4 botulinum toxin A
9 Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males Completed NCT01067391 Phase 4 tadalafil;placebo
10 Slow Initial β-lactam Infusion With High-dose Paracetamol to Improve the Outcomes of Childhood Bacterial Meningitis Completed NCT01540838 Phase 4 Infusion with paracetamol;Bolus without paracetamol
11 Nerve Transfer Reconstruction in the Tetraplegic Upper Extremity Recruiting NCT01579604 Phase 4
12 SCIPA (Spinal Cord Injury and Physical Activity) Hands-On: Early Intensive Hand Rehabilitation After Spinal Cord Injury Unknown status NCT01086930 Phase 3
13 Retraining Walking After Spinal Cord Injury Unknown status NCT00059553 Phase 2, Phase 3
14 Exhaled Levels of Nitric Oxide Completed NCT00753948 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
15 Prevention of Low Blood Pressure in Persons With Tetraplegia Completed NCT00237770 Phase 2, Phase 3 N-Nitro L-arginine-methylester (L-NAME)
16 MEOPA to Improve Physical Therapy Results After Multilevel Surgery Completed NCT00632528 Phase 3 MEOPA;Medicinal air
17 In-home Telerehabilitation for Quadriplegic Hand Function Completed NCT00656149 Phase 2, Phase 3
18 Combined Robotic Training and tDCS in Chronic SCI Recruiting NCT03555838 Phase 3
19 Restoration of Upper Limb Function in Individuals With Sub-Acute Spinal Cord Injury Active, not recruiting NCT01292811 Phase 3
20 Fenofibrate Treatment in SCI Active, not recruiting NCT02455336 Phase 2, Phase 3 Fenofibrate
21 Study of the Impact of the Use of a Corset on the Respiratory Function of Patients With Spinal Cord Injury Withdrawn NCT01569360 Phase 3
22 Cethrin in Acute Cervical Spinal Cord Injury Withdrawn NCT02053883 Phase 2, Phase 3 Cethrin (BA-210);Placebo
23 Spinal Cord Neuromodulation for SCI Unknown status NCT02313194 Phase 1, Phase 2
24 Rehabilitation of the Upper Extremity With Enhanced Proprioceptive Feedback Following Incomplete Spinal Cord Injury Unknown status NCT00833105 Phase 1, Phase 2
25 Surgical Management of Spinal Cord Injuries In Neck Unknown status NCT00475748 Phase 2
26 Safety and Efficacy of L-NAME and Midodrine to Increase MAP Completed NCT00835224 Phase 2 L-NAME;Midodrine;Placebo
27 Spinal Cord Injury Leg Rehabilitation Completed NCT01498991 Phase 1, Phase 2
28 FES Therapy:Restoring Voluntary Grasping Function in Chronic SCI Completed NCT01208688 Phase 2
29 A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries Completed NCT00500812 Phase 1, Phase 2 Cethrin
30 The Effects of Passive Gait Training in Complete Motor Spinal Cord Injury (SCI) Completed NCT01349478 Phase 1, Phase 2
31 Study to Assess Safety, Tolerability and MTD of a Central Pattern Generator-activating Tritherapy (SPINALON) in Patients With Chronic Spinal Cord Injury Completed NCT01484184 Phase 1, Phase 2 SPINALON (buspirone + levodopa + cardidopa)
32 Olaparib and Atezolizumab Either Alone or in Combination in Treating Patients With Stage III-IV Triple Negative Breast Cancer Recruiting NCT02849496 Phase 2 Atezolizumab;Olaparib
33 Dose Escalation Study of AST-OPC1 in Spinal Cord Injury Active, not recruiting NCT02302157 Phase 1, Phase 2
34 24hr Effects of Tiotropium Bromide in Tetraplegia Enrolling by invitation NCT02586649 Phase 2 Tiotropium Bromide;Placebo
35 Autologous Incubated Macrophages for Patients With Complete Spinal Cord Injuries Suspended NCT00073853 Phase 2
36 Cannabis for Spasticity in Multiple Sclerosis Terminated NCT00682929 Phase 1, Phase 2 Inhaled Cannabis;Oral THC;Oral Placebo;Inhaled placebo
37 Effect of Air-stacking on Peak Cough Flow in Patients With Acute Cervical or High Thoracic Spinal Cord Injury Withdrawn NCT01046175 Phase 2
38 Effects of Anticholinergic or Long-Acting Beta 2 Agonist on FeNO and Pulmonary Function in SCI Unknown status NCT01355991 Phase 1 Tiotropium;Salmeterol
39 Acute and Chronic Effects of Inhaled Steroids on Pulmonary Function in Persons With Spinal Cord Injury Unknown status NCT01353599 Phase 1 Mometasone furoate
40 The Role of Melatonin in the Regulation of Blood Coagulation Completed NCT01741389 Phase 1 Melatonin ("Circadin")
41 Evaluation of a Tongue Operated Assistive Technology for Individuals With Severe Paralysis Completed NCT01124292 Phase 1
42 Use of Interactive Gaming for Enhanced Function After Spinal Cord Injury Completed NCT01537978 Phase 1
43 The Safety of ahSC in Chronic SCI With Rehabilitation Recruiting NCT02354625 Phase 1
44 Improving Ambulatory Community Access After Paralysis Recruiting NCT01570816 Phase 1
45 Abdominal Functional Electrical Stimulation in Tetraplegia Unknown status NCT00202631 Not Applicable
46 Electrical Activation of The Diaphragm for Ventilatory Assist Unknown status NCT00010374 Not Applicable
47 Abdominal Functional Electrical Stimulation Training and Its Effect on Mechanical Insufflation-Exsufflation Unknown status NCT01800409 Not Applicable
48 Multicenter National Randomized Controlled Open Label Study Assessing Interest of Non Invasive Ventilation in out-of Hospital Setting During Acute Respiratory Failure in Chronic Obstructive Pulmonary Disease Patients. VeNIS BPCO Unknown status NCT01626937 Not Applicable
49 Body Composition Assessment in Spinal Cord Injury Unknown status NCT00957762
50 Early Intervention to Reduce Bone Loss After Spinal Cord Injury Unknown status NCT02334410 Not Applicable

Search NIH Clinical Center for Quadriplegia

Genetic Tests for Quadriplegia

Genetic tests related to Quadriplegia:

# Genetic test Affiliating Genes
1 Tetraplegia 29

Anatomical Context for Quadriplegia

MalaCards organs/tissues related to Quadriplegia:

41
Spinal Cord, Brain, Bone, Tongue, Lung, Heart, Prostate

Publications for Quadriplegia

Articles related to Quadriplegia:

(show top 50) (show all 567)
# Title Authors Year
1
Life-Threatening Hypokalemic Quadriplegia in a Postoperative Patient. ( 29482687 )
2018
2
Descriptive pilot study of vividness and temporal equivalence during motor imagery training after quadriplegia. ( 29944923 )
2018
3
Acute Onset of Quadriplegia Secondary to Hypoparathyroidism: Mimicker of AMAN Variant of GBS. ( 29482695 )
2018
4
Nonsurgical management of an extensive spontaneous spinal epidural hematoma causing quadriplegia and respiratory distress in a choledocholithiasis patient: A case report: Erratum. ( 29369212 )
2018
5
Effects of Walkbot gait training on kinematics, kinetics, and clinical gait function in paraplegia and quadriplegia. ( 29660947 )
2018
6
Midline depressed skull fracture presenting with quadriplegia: A rare phenomenon. ( 28458953 )
2017
7
Voluntary activation of biceps-to-triceps and deltoid-to-triceps transfers in quadriplegia. ( 28253262 )
2017
8
Nonsurgical management of an extensive spontaneous spinal epidural hematoma causing quadriplegia and respiratory distress in a choledocholithiasis patient: A case report. ( 29390530 )
2017
9
Transient Hypokalemic Quadriplegia After a Lumbar Transforaminal Epidural Dexamethasone Injection: A Case Report. ( 29074369 )
2017
10
Quadriplegia post-coronary artery bypass graft surgery: an unusual case. ( 28823182 )
2017
11
Acute-Onset Quadriplegia With Recovery After High-Voltage Electrical Injury. ( 28953517 )
2017
12
Quadriplegia caused by an epidural abscess occurring at the same level of cervical destructive spondyloarthropathy: a case report. ( 28068970 )
2017
13
Acute quadriplegia following a minimal injury in the posterior pharyngeal wall by a fishbone. ( 28544487 )
2017
14
Active elbow flexion is possible in C4 quadriplegia using hybrid assistive limb (HALAr) technology: A case study. ( 28355990 )
2017
15
Magnetic resonance imaging of the upper airway in patients with quadriplegia and obstructive sleep apnea. ( 29082563 )
2017
16
Wisdom from a Chair: Thirty Years of Quadriplegia: A Memoir by Andrew I. Batavia and Mitchell Batavia. ( 28131160 )
2017
17
WDR45B-related intellectual disability, spastic quadriplegia, epilepsy, and cerebral hypoplasia: A consistent neurodevelopmental syndrome. ( 28503735 )
2017
18
A severe female case of arthrogryposis multiplex congenita with brain atrophy, spastic quadriplegia and intellectual disability caused by ZC4H2 mutation. ( 29254829 )
2017
19
Correspondence: Skeletal Maturation and Mineralization of Children with Moderate to Severe Spastic Quadriplegia. ( 28571225 )
2017
20
Quadriplegia Due to Injury of Corticofugal Tracts from Secondary Motor Area in a Patient With Severe Traumatic Brain Injury. ( 28301868 )
2017
21
Disseminated coccidioidomycosis-related cervical intramedullary lesion causing quadriplegia in an immunocompetent host. ( 29237660 )
2017
22
Fracture-dislocation at C6-C7 level with Quadriplegia after Traditional Massage in a Patient with Ankylosing Spondylitis: A Case Report. ( 29021885 )
2017
23
Neural repair and rehabilitation: Man with quadriplegia uses brainwaves to control his forearm muscles. ( 27125635 )
2016
24
Decrease of spasticity after hybrid assistive limb(Ar) training for a patient with C4 quadriplegia due to chronic SCI. ( 27762171 )
2016
25
Orthodontic treatment and follow-up of a patient with cerebral palsy and spastic quadriplegia. ( 27692425 )
2016
26
Permanent Quadriplegia Following Replacement of Voice Prosthesis. ( 28005804 )
2016
27
Restoring cortical control of functional movement in a human with quadriplegia. ( 27074513 )
2016
28
Correlations between risk factors and functional evolution in patients with spastic quadriplegia. ( 27453749 )
2016
29
Permanent Quadriplegia Following Replacement of Voice Prosthesis. ( 27617810 )
2016
30
The benefits of a comprehensive rehabilitation program in patients diagnosed with spastic quadriplegia. ( 27974931 )
2016
31
Variability Analysis on Gestures for People With Quadriplegia. ( 28113307 )
2016
32
Rapidly Progressive Quadriplegia and Encephalopathy. ( 27598246 )
2016
33
Self-catheterization activity in women with quadriplegia: occupational therapy and achievement of independence. ( 27271231 )
2016
34
Living Brain to Hand: Bypassing Spinal Cord Quadriplegia Using a Novel Neuroprosthesis. ( 27428636 )
2016
35
Skeletal Maturation and Mineralisation of Children with Moderate to Severe Spastic Quadriplegia. ( 27504366 )
2016
36
Big data challenges in decoding cortical activity in a human with quadriplegia to inform a brain computer interface. ( 28268963 )
2016
37
Acute Traumatic Quadriplegia in Adults: Predictors of Acute in-Hospital Mortality. ( 27651339 )
2016
38
Intraspinal hypotension syndrome presents as transient quadriplegia. ( 27766904 )
2016
39
Using an Artificial Neural Bypass to Restore Cortical Control of Rhythmic Movements in a Human with Quadriplegia. ( 27658585 )
2016
40
Aspiration, quadriplegia, incontinence. ( 26607791 )
2016
41
Poster 472 8-Year-Old Male with Flaccid Quadriplegia After Bone Marrow Transplant: A Case Report. ( 27673216 )
2016
42
Quadriplegia Following Epileptic Seizure : Things to Keep in Mind. ( 27226869 )
2016
43
Development of stroke-induced quadriplegia after endovascular repair of blunt aortic injury pseudoaneurysm. ( 25630782 )
2015
44
Post-operative quadriplegia as the initial manifestation of tumefactive multiple sclerosis. ( 26195864 )
2015
45
Progressive quadriplegia resulting from septic facet joint arthritis. ( 26223077 )
2015
46
Paraplegia-quadriplegia Independently Increases All Percutaneous Nephrolithotomy Complications: A Comparative Study Using the Modified Clavien System. ( 25770730 )
2015
47
Plasma Tumor Necrosis Factor-alpha (TNF-I+) Levels Correlate with Disease Severity in Spastic Diplegia, Triplegia, and Quadriplegia in Children with Cerebral Palsy. ( 26656070 )
2015
48
Delayed transient post-traumatic quadriplegia. ( 25960840 )
2015
49
A slow progressor HIV-infected boy developing quadriplegia with evidence of Epstein-Barr virus associated smooth muscle tumour of the cervical spinal cord. ( 26123466 )
2015
50
Management of a 3-year-old with an unstable C6-C7 diastasis without quadriplegia. ( 26077099 )
2015

Variations for Quadriplegia

Expression for Quadriplegia

Search GEO for disease gene expression data for Quadriplegia.

Pathways for Quadriplegia

GO Terms for Quadriplegia

Cellular components related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase complex GO:0005890 8.96 ATP1A2 ATP1A3
2 extracellular vesicle GO:1903561 8.8 ATP1A2 ATP1A3 SPTAN1

Biological processes related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sphingolipid biosynthetic process GO:0030148 9.48 ALDH3A2 ELOVL4
2 potassium ion import GO:0010107 9.46 ATP1A2 ATP1A3
3 ATP hydrolysis coupled proton transport GO:0015991 9.43 ATP1A2 ATP1A3
4 cellular sodium ion homeostasis GO:0006883 9.4 ATP1A2 ATP1A3
5 cellular potassium ion homeostasis GO:0030007 9.37 ATP1A2 ATP1A3
6 sodium ion export across plasma membrane GO:0036376 9.32 ATP1A2 ATP1A3
7 cellular response to steroid hormone stimulus GO:0071383 9.26 ATP1A2 ATP1A3
8 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 9.16 ATP1A2 ATP1A3
9 cell communication by electrical coupling involved in cardiac conduction GO:0086064 8.96 ATP1A2 ATP1A3
10 response to glycoside GO:1903416 8.62 ATP1A2 ATP1A3

Molecular functions related to Quadriplegia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 9.16 ATP1A2 ATP1A3
2 chaperone binding GO:0051087 9.13 ATP1A2 ATP1A3 TBCD
3 steroid hormone binding GO:1990239 8.62 ATP1A2 ATP1A3

Sources for Quadriplegia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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