MCID: RDL004
MIFTS: 27

Radial Neuropathy

Categories: Neuronal diseases

Aliases & Classifications for Radial Neuropathy

MalaCards integrated aliases for Radial Neuropathy:

Name: Radial Neuropathy 12 15 74

Classifications:



External Ids:

Disease Ontology 12 DOID:12171
MeSH 45 D020425
SNOMED-CT 69 16644004
UMLS 74 C0748226

Summaries for Radial Neuropathy

MalaCards based summary : Radial Neuropathy is related to radial nerve lesion and neuropathy. An important gene associated with Radial Neuropathy is SERPINI2 (Serpin Family I Member 2), and among its related pathways/superpathways are Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers and Thyroid hormone signaling pathway. Affiliated tissues include skin, and related phenotype is endocrine/exocrine gland.

Wikipedia : 77 Radial neuropathy (or radial mononeuropathy) is a type of mononeuropathy which results from acute trauma... more...

Related Diseases for Radial Neuropathy

Diseases related to Radial Neuropathy via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 radial nerve lesion 11.7
2 neuropathy 10.5
3 lipomatosis, multiple 9.8
4 pleomorphic lipoma 9.8
5 sarcoma 9.8
6 fasciitis 9.8
7 osteochondroma 9.8
8 soft tissue sarcoma 9.8
9 tricuspid valve stenosis 9.5 NOTCH1 SERPINA1

Graphical network of the top 20 diseases related to Radial Neuropathy:



Diseases related to Radial Neuropathy

Symptoms & Phenotypes for Radial Neuropathy

MGI Mouse Phenotypes related to Radial Neuropathy:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 8.92 GSN NOTCH1 SERPINI2 THRB

Drugs & Therapeutics for Radial Neuropathy

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Delto-Tricipital Compression Syndrome: Treated With Injection of Dextrose Unknown status NCT02331069 Not Applicable Dextrose 5% (D5W)
2 Tendon Transfer for Irreversible Radial Nerve Palsy, Does it Help?Retrospective Cohort From Level-1 Trauma Center. Completed NCT03936868
3 Fractures of the Humeral Shaft With Primary Radial Nerve Palsy Completed NCT03948542
4 Quantitation of McArdle's Sign and Evaluation of Specificity for Multiple Sclerosis Completed NCT03122873
5 Neuromuscular Ultrasound for Focal Neuropathies Completed NCT01394822

Search NIH Clinical Center for Radial Neuropathy

Genetic Tests for Radial Neuropathy

Anatomical Context for Radial Neuropathy

MalaCards organs/tissues related to Radial Neuropathy:

42
Skin

Publications for Radial Neuropathy

Articles related to Radial Neuropathy:

(show all 33)
# Title Authors Year
1
Compressive radial neuropathy by a synovial cyst during pregnancy: A clinical case report. ( 30544430 )
2018
2
Investigation of the Diagnostic Value of Ultrasonography for Radial Neuropathy Located at the Spiral Groove. ( 30180530 )
2018
3
Reversible reddish skin color change in a patient with compressive radial neuropathy. ( 30129424 )
2018
4
Electrophysiologic Features of Radial Neuropathy in Childhood and Adolescence. ( 29506771 )
2018
5
Radial neuropathy following arterial line removal: A rare complication from a routine ICU procedure. ( 29511544 )
2018
6
Acute Radial Neuropathy at the Spiral Groove Following Massage: A Case Presentation. ( 28400223 )
2017
7
Poster 279 Radial Neuropathy Exacerbated by Ligamentous Laxity in Pregnancy and by Chemotherapy: A Case Report. ( 27673036 )
2016
8
Posterior interosseous neuropathy: Supinator syndrome vs fascicular radial neuropathy. ( 27683851 )
2016
9
Ultrasonographic and Surgical Findings of Acute Radial Neuropathy Following Blunt Trauma. ( 27763908 )
2016
10
The usefulness of proximal radial motor conduction in acute compressive radial neuropathy. ( 25851897 )
2015
11
Clinical features of wrist drop caused by compressive radial neuropathy and its anatomical considerations. ( 24851150 )
2014
12
Compressive radial neuropathy developed under a fibrotic band associated with rhabdomyolysis and successfully treated with surgery. ( 25024970 )
2014
13
Prognosis of acute compressive radial neuropathy. ( 22581545 )
2012
14
Diagnostic ultrasound for traumatic radial neuropathy. ( 20531154 )
2011
15
Compressive radial neuropathy induced by 'hooking' manoeuvre in a tetraplegic person. ( 20877330 )
2011
16
High-resolution 3T MR neurography of radial neuropathy. ( 21782245 )
2011
17
Superficial radial neuropathy and brachioradial motor nerve palsy associated with proximal radius osteochondroma. ( 20496292 )
2010
18
Radial neuropathy due to occupational lead exposure: Phenotypic and electrophysiological characteristics of five patients. ( 20142857 )
2009
19
Fasciitis ossificans with a radial neuropathy: a benign differential diagnosis for soft tissue sarcoma. ( 17240146 )
2007
20
Prognostic values of electrodiagnostic studies in traumatic radial neuropathy. ( 17587226 )
2007
21
Posterior antebrachial cutaneous nerve conduction study in radial neuropathy. ( 15337623 )
2004
22
A high radial neuropathy by parosteal lipoma compression. ( 12195259 )
2002
23
Superficial radial neuropathy following venepuncture. ( 11501238 )
2001
24
Maternal Bilateral Radial Neuropathy During Childbirth in Hereditary Neuropathy With a Predisposition to Pressure Palsies (HNPP). ( 19078571 )
2000
25
Radial neuropathy. ( 10393751 )
1999
26
Superficial radial neuropathy caused by intravenous injection. ( 10427357 )
1999
27
Isolated triceps weakness in exercise-induced radial neuropathy. ( 9062054 )
1996
28
Femoral and radial neuropathy following vascular access cannulation for hemodialysis. ( 7753288 )
1995
29
Avulsion of the triceps brachii with selective radial neuropathy. ( 7761319 )
1995
30
Windmill pitcher's radial neuropathy. ( 8084398 )
1994
31
Localized constrictive radial neuropathy in the absence of extrinsic compression: three cases. ( 6693752 )
1984
32
Treatment of radial neuropathy associated with fractures of the humerus. ( 7462281 )
1981
33
Superficial radial neuropathy. ( 1158953 )
1975

Variations for Radial Neuropathy

Expression for Radial Neuropathy

Search GEO for disease gene expression data for Radial Neuropathy.

Pathways for Radial Neuropathy

Pathways related to Radial Neuropathy according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.28 NOTCH1 SERPINA1
2 11.02 NOTCH1 THRB
3 10.52 NOTCH1 THRB

GO Terms for Radial Neuropathy

Cellular components related to Radial Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.26 GSN NOTCH1 SERPINA1 SERPINI2
2 ficolin-1-rich granule lumen GO:1904813 8.62 GSN SERPINA1

Biological processes related to Radial Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cilium assembly GO:0060271 9.37 GSN NOTCH1
2 transcription initiation from RNA polymerase II promoter GO:0006367 9.32 NOTCH1 THRB
3 negative regulation of endopeptidase activity GO:0010951 9.26 SERPINA1 SERPINI2
4 negative regulation of peptidase activity GO:0010466 9.16 SERPINA1 SERPINI2
5 regulation of cell adhesion GO:0030155 8.96 GSN SERPINI2
6 tissue regeneration GO:0042246 8.62 GSN NOTCH1

Molecular functions related to Radial Neuropathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase inhibitor activity GO:0030414 9.16 SERPINA1 SERPINI2
2 serine-type endopeptidase inhibitor activity GO:0004867 8.96 SERPINA1 SERPINI2
3 chromatin DNA binding GO:0031490 8.62 NOTCH1 THRB

Sources for Radial Neuropathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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