MCID: RDT001
MIFTS: 32

Radiation Cystitis

Categories: Nephrological diseases

Aliases & Classifications for Radiation Cystitis

MalaCards integrated aliases for Radiation Cystitis:

Name: Radiation Cystitis 12 15
Irradiation Cystitis 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:7127
ICD10 33 N30.4
ICD9CM 35 595.82
NCIt 50 C123174
SNOMED-CT 68 11251000
UMLS 73 C0156270

Summaries for Radiation Cystitis

MalaCards based summary : Radiation Cystitis, also known as irradiation cystitis, is related to cystitis and urethra adenocarcinoma. An important gene associated with Radiation Cystitis is EGR3 (Early Growth Response 3), and among its related pathways/superpathways is MAPK signaling pathway. Affiliated tissues include prostate, cervix and thyroid, and related phenotype is homeostasis/metabolism.

Related Diseases for Radiation Cystitis

Graphical network of the top 20 diseases related to Radiation Cystitis:



Diseases related to Radiation Cystitis

Symptoms & Phenotypes for Radiation Cystitis

MGI Mouse Phenotypes related to Radiation Cystitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.44 CACNA1C EGR3 ELAVL3 F7 GATM MAPK8IP1

Drugs & Therapeutics for Radiation Cystitis

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Radiation Induced Cystitis Treated With Hyperbaric Oxygen - A Randomized Controlled Trial Completed NCT01659723 Phase 2, Phase 3 Hyperbaric Oxygen
2 Hyperbaric Oxygen Therapy for Inflammatory Conditions of the Urinary Bladder Recruiting NCT03143920 Early Phase 1
3 Hyperbaric Oxygenation Treatment and Quality of Life Not yet recruiting NCT03570229

Search NIH Clinical Center for Radiation Cystitis

Genetic Tests for Radiation Cystitis

Anatomical Context for Radiation Cystitis

MalaCards organs/tissues related to Radiation Cystitis:

41
Prostate, Cervix, Thyroid, Uterus

Publications for Radiation Cystitis

Articles related to Radiation Cystitis:

(show top 50) (show all 77)
# Title Authors Year
1
Photoselective Vaporisation of the Bladder for the Management of Radiation Cystitis - Technique and Initial Outcomes. ( 29777786 )
2018
2
Protein and micronutrient deficiencies in patients with radiation cystitis and outcome after hyperbaric oxygen therapy. ( 29460790 )
2018
3
Changes in the Neuronal Control of the Urinary Bladder in a Model of Radiation Cystitis. ( 29530925 )
2018
4
Altered Angiogenic Growth Factors in Urine of Prostate Cancer Survivors With Radiation History and Radiation Cystitis. ( 30059715 )
2018
5
Current management of radiation cystitis: a review and practical guide to clinical management. ( 30113758 )
2018
6
ENDOSCOPIC INTRAVESICAL FIBRIN GLUE APPLICATION IN THE TREATMENT OF REFRACTORY HEMORRHAGIC RADIATION CYSTITIS: A SINGLE COHORT PILOT STUDY. ( 30280911 )
2018
7
Correlation between urinary dose and delayed radiation cystitis after 78A Gy intensity-modulated radiotherapy for high-risk prostate cancer: A 10-year follow-up study of genitourinary toxicity in clinical practice. ( 29594221 )
2017
8
Hyperbaric, Radiation Cystitis ( 29261976 )
2017
9
Cumulative incidence and predictive factors of radiation cystitis in patients with localized prostate cancer. ( 29169704 )
2017
10
Ureteral Embolization to Prevent Thrombotic Obstruction of Nephrostomy Catheters in the Context of Refractory Hemorrhagic Radiation Cystitis with Severe Vesicoureteral Reflux. ( 27019759 )
2016
11
Hyperbaric Oxygen Therapy for Radiation Cystitis. ( 27637115 )
2016
12
Intravesical Liposomal Tacrolimus Protects Against Radiation Cystitis Induced by 3-Beam Targeted Bladder Radiation. ( 25839382 )
2015
13
Innovative use of intravesical tacrolimus for hemorrhagic radiation cystitis. ( 26347076 )
2015
14
A Narrative Review on the Pathophysiology and Management for Radiation Cystitis. ( 26798335 )
2015
15
Modeling and Treatment of Radiation Cystitis. ( 26571081 )
2015
16
Sodium hyaluronate and chondroitin sulfate replenishment therapy can improve nocturia in men with post-radiation cystitis: results of a prospective pilot study. ( 26148853 )
2015
17
Intravesical Therapies for Radiation Cystitis. ( 30263021 )
2015
18
Standardized cranberry capsules for radiation cystitis in prostate cancer patients in New Zealand: a randomized double blinded, placebo controlled pilot study. ( 24993395 )
2015
19
Advances in Therapeutic Development for Radiation Cystitis. ( 26663493 )
2014
20
Successful use of endoscopic argon plasma coagulation for hemorrhagic radiation cystitis: a case report. ( 24837598 )
2014
21
Early urinary diversion with ileal conduit and vesicovaginostomy in the treatment of radiation cystitis due to carcinoma cervix: a study from a tertiary care hospital in South India. ( 25366250 )
2014
22
Evaluation of the impact of the urinary symptoms on quality of life of patients with painful bladder syndrome/chronic pelvic pain and radiation cystitis: EURCIS study. ( 24360594 )
2013
23
Hyperbaric oxygen therapy for hemorrhagic radiation cystitis. ( 23516773 )
2013
24
Hyperbaric oxygen therapy for hemorrhagic radiation cystitis. ( 23516766 )
2013
25
Hemorrhagic Radiation Cystitis. ( 24322335 )
2013
26
Radiation cystitis with pseudocarcinomatous urothelial hyperplasia. ( 24045222 )
2013
27
Possible risk factors associated with radiation proctitis or radiation cystitis in patients with cervical carcinoma after radiotherapy. ( 23464440 )
2012
28
A cost-analysis case study of radiation cystitis treatment including hyperbaric oxygen therapy. ( 22828818 )
2012
29
Hyperbaric oxygen therapy for radiation cystitis in patients with prostate cancer: a long-term follow-up study. ( 22797611 )
2012
30
Vascular therapy for radiation cystitis. ( 21412823 )
2011
31
Treatment of acute radiation cystitis: comment. ( 21739326 )
2011
32
Prophylactic vesical instillations with 0.2% chondroitin sulfate may reduce symptoms of acute radiation cystitis in patients undergoing radiotherapy for gynecological malignancies. ( 21365332 )
2011
33
Recombinant activated factor VII to control life-threatening haemorrhagic radiation cystitis. ( 19352582 )
2010
34
Management of radiation cystitis. ( 20212517 )
2010
35
Efficacy of sodium hyaluronate in the management of chemical and radiation cystitis. ( 20562794 )
2010
36
Is treatment of hemorrhagic radiation cystitis with hyperbaric oxygen effective? ( 20224264 )
2010
37
Radiation cystitis: indication for hyperbaric oxygen. ( 18325711 )
2009
38
Radiation cystitis. ( 19625037 )
2009
39
A new minimally invasive technique for treating radiation cystitis: the argon-beam coagulator. ( 16925761 )
2006
40
A phase II study to evaluate WF10 in patients with late hemorrhagic radiation cystitis and proctitis. ( 16169580 )
2006
41
Sexual function after partial cystectomy and urothelial stripping in a 32-year-old woman with radiation cystitis. ( 15647882 )
2005
42
Reduced recurrence of late hemorrhagic radiation cystitis by WF10 therapy in cervical cancer patients: a multicenter, randomized, two-arm, open-label trial. ( 15542165 )
2004
43
Rupture of urachal diverticulum in radiation cystitis and neurogenic bladder dysfunction after radical hysterectomy. ( 15479303 )
2004
44
Non-surgical interventions for late radiation cystitis in patients who have received radical radiotherapy to the pelvis. ( 12137633 )
2002
45
Intravesicle formalin instillation with a modified technique for controlling haemorrhage secondary to radiation cystitis. ( 12376221 )
2002
46
Hyperbaric oxygen for the treatment of radiation cystitis and proctitis. ( 12084193 )
2002
47
Successful treatment of radiation cystitis with hyperbaric oxygen therapy: resolution of bleeding event and changes of histopathological findings of the bladder mucosa. ( 9696331 )
1998
48
Endoscopic topical placement of formalin soaked pledgets to control localized hemorrhage due to radiation cystitis. ( 9224340 )
1997
49
Effective hyperbaric oxygenation with prostaglandin E1 for radiation cystitis and colitis after pelvic radiotherapy. ( 9061423 )
1996
50
Hyperbaric oxygen treatment for haemorrhagic radiation cystitis. ( 7674746 )
1995

Variations for Radiation Cystitis

Expression for Radiation Cystitis

Search GEO for disease gene expression data for Radiation Cystitis.

Pathways for Radiation Cystitis

Pathways related to Radiation Cystitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.69 CACNA1C HGF MAPK8IP1 MAPK8IP2 PGF

GO Terms for Radiation Cystitis

Cellular components related to Radiation Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Z disc GO:0030018 8.8 CACNA1C NOS1 TCAP

Biological processes related to Radiation Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.65 EGR3 HGF MAPK8IP1 MIF XIAP
2 regulation of signaling receptor activity GO:0010469 9.55 HGF MAPK8IP2 MIF PGF RLN2
3 positive regulation of angiogenesis GO:0045766 9.54 HGF PGF RLN2
4 regulation of JNK cascade GO:0046328 9.32 MAPK8IP1 MAPK8IP2
5 positive chemotaxis GO:0050918 9.13 HGF MIF PGF
6 animal organ regeneration GO:0031100 8.8 F7 HGF PGF

Molecular functions related to Radiation Cystitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MAP-kinase scaffold activity GO:0005078 8.96 MAPK8IP1 MAPK8IP2
2 chemoattractant activity GO:0042056 8.8 HGF MIF PGF

Sources for Radiation Cystitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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