MCID: RDT004
MIFTS: 17

Radiation Induced Brachial Plexopathy

Categories: Rare diseases

Aliases & Classifications for Radiation Induced Brachial Plexopathy

MalaCards integrated aliases for Radiation Induced Brachial Plexopathy:

Name: Radiation Induced Brachial Plexopathy 52 71
Radiation Injury to the Brachial Plexus 52
Radiation Induced Brachial Neuritis 52

Classifications:



External Ids:

UMLS 71 C2931145

Summaries for Radiation Induced Brachial Plexopathy

MalaCards based summary : Radiation Induced Brachial Plexopathy, also known as radiation injury to the brachial plexus, is related to plexopathy and breast cancer. The drugs Tocopherol and Clodronate have been mentioned in the context of this disorder. Affiliated tissues include breast, lung and spinal cord.

Related Diseases for Radiation Induced Brachial Plexopathy

Diseases related to Radiation Induced Brachial Plexopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 plexopathy 10.8
2 breast cancer 10.3
3 nasopharyngeal carcinoma 10.3
4 lung cancer 10.1
5 squamous cell carcinoma, head and neck 10.1
6 brachial plexus neuropathy 10.1
7 47,xyy 10.1
8 chronic pain 10.1
9 paresthesia 10.1
10 radiation-induced plexopathy 10.1
11 neuritis 10.1

Graphical network of the top 20 diseases related to Radiation Induced Brachial Plexopathy:



Diseases related to Radiation Induced Brachial Plexopathy

Symptoms & Phenotypes for Radiation Induced Brachial Plexopathy

Drugs & Therapeutics for Radiation Induced Brachial Plexopathy

Drugs for Radiation Induced Brachial Plexopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 18)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tocopherol Approved, Investigational Phase 3 1406-66-2, 54-28-4 14986
2
Clodronate Approved, Investigational, Vet_approved Phase 3 10596-23-3 25419
3
Pentoxifylline Approved, Investigational Phase 3 6493-05-6 4740
4
Vitamin E Approved, Nutraceutical, Vet_approved Phase 3 59-02-9 14985
5 Tocotrienol Investigational Phase 3 6829-55-6
6 Vitamins Phase 3
7 Trace Elements Phase 3
8 Micronutrients Phase 3
9 Free Radical Scavengers Phase 3
10 Tocopherols Phase 3
11 Platelet Aggregation Inhibitors Phase 3
12 Nutrients Phase 3
13 Tocotrienols Phase 3
14 Vasodilator Agents Phase 3
15 Antioxidants Phase 3
16 Protective Agents Phase 3
17 Phosphodiesterase Inhibitors Phase 3
18 Radiation-Protective Agents Phase 3

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Randomized Clinical Trial Evaluating Combined Pentoxifylline-tocopherol-clodronate vs Placebo in Radiation-induced Brachial Plexopathy: the PENTOCLO Trial Completed NCT01291433 Phase 3 Pentoxifylline placebo;Pentoxifylline;Tocopherol acetate;Clodronic Acid;Tocopherol placebo;Clodronate placebo
2 Does Hyperbaric Oxygen Therapy (HBOT) Reduce Pain, Improve Depression and Impact on Patients' Quality of Life for Those Suffering From Late Radiation Tissue Injury? Recruiting NCT02425215

Search NIH Clinical Center for Radiation Induced Brachial Plexopathy

Genetic Tests for Radiation Induced Brachial Plexopathy

Anatomical Context for Radiation Induced Brachial Plexopathy

MalaCards organs/tissues related to Radiation Induced Brachial Plexopathy:

40
Breast, Lung, Spinal Cord

Publications for Radiation Induced Brachial Plexopathy

Articles related to Radiation Induced Brachial Plexopathy:

(show all 42)
# Title Authors PMID Year
1
Hyperbaric oxygen therapy for radiation-induced brachial plexopathy, a case report and literature review. 61
31762694 2020
2
The radiation dose tolerance of the brachial plexus: A systematic review and meta-analysis. 61
31309161 2019
3
Radiation-induced brachial plexus toxicity after SBRT of apically located lung lesions. 61
31066326 2019
4
Microneurosurgical treatment options in peripheral nerve compression syndromes after chemotherapy and radiation treatment. 61
30261113 2018
5
Clinical Utility of (18)F-FDG PET/CT in brachial plexopathy secondary to metastatic breast cancer. 61
27095861 2016
6
Radiation-induced brachial plexopathy in patients with nasopharyngeal carcinoma: a retrospective study. 61
26934119 2016
7
Early transient radiation-induced brachial plexopathy in locally advanced head and neck cancer. 61
27095943 2016
8
Brachial plexus dose tolerance in head and neck cancer patients treated with sequential intensity modulated radiation therapy. 61
25927572 2015
9
Free functioning muscle transfer in radiation-induced brachial plexopathy: case report. 61
25155695 2014
10
Managing the consequences of cancer treatment and the English National Cancer Survivorship Initiative. 61
23237053 2013
11
Brachial plexopathy in apical non-small cell lung cancer treated with definitive radiation: dosimetric analysis and clinical implications. 61
22658442 2013
12
Radiation-induced neuropathy in cancer survivors. 61
23245644 2012
13
[Radiation-induced neuropathies: collateral damage of improved cancer prognosis]. 61
22742890 2012
14
Dose constraints to prevent radiation-induced brachial plexopathy in patients treated for lung cancer. 61
22284035 2012
15
Brachial plexopathy after chemoradiotherapy for head and neck squamous cell carcinoma. 61
20814659 2010
16
Brachial neuropathy 22 years after radiation therapy for fibrosarcoma: a case report. 61
19918550 2009
17
Nerve transfer for elbow flexion in radiation-induced brachial plexopathy: a case report. 61
18843522 2009
18
[Radiation myelopathy and plexopathy]. 61
18306658 2008
19
Radiation-induced brachial plexopathy and hypofractionated regimens in adjuvant irradiation of patients with breast cancer--a review. 61
16644570 2006
20
Double-blind randomised phase II study of hyperbaric oxygen in patients with radiation-induced brachial plexopathy. 61
16216362 2005
21
Radiation-induced conduction block: resolution following anticoagulant therapy. 61
15635681 2005
22
A patient questionnaire for radiation-induced brachial plexopathy. 61
14758125 2004
23
Radiation-induced brachial plexopathy: review. Complication without a cure. 61
15011123 2004
24
Diagnosis and operative treatment of radiation-induced brachial plexopathy. 61
12443571 2002
25
Radiation-induced brachial plexopathy in women treated for carcinoma of the breast. 61
11911514 2002
26
Double-blind randomized phase II study of hyperbaric oxygen in patients with radiation-induced brachial plexopathy. 61
11230889 2001
27
Occupational therapy intervention with radiation-induced brachial plexopathy. 61
9697448 1998
28
Brachial plexus neuropathy following mantle radiotherapy. 61
9890543 1998
29
Radiation-induced brachial plexopathy: MR imaging. 61
9194228 1997
30
Electrophysiological findings in patients who received radiation therapy over the brachial plexus: a magnetic stimulation study. 61
9020820 1996
31
Radiation-induced brachial plexopathy: MR and clinical findings. 61
8933882 1996
32
Results of DREZ coagulations for pain related to plexus lesions, spinal cord injuries and postherpetic neuralgia. 61
8738385 1996
33
Fasciculation-myokymic activity and prolonged nerve conduction block. A physiopathological relationship in radiation-induced brachial plexopathy. 61
7507424 1993
34
Radiation-induced brachial plexopathy: neurological follow-up in 161 recurrence-free breast cancer patients. 61
8387067 1993
35
Dorsal root entry zone lesions in the treatment of pain related to radiation-induced brachial plexopathy. 61
8382542 1993
36
Radiation-induced brachial plexopathy: clinical and electromyographical (EMG) considerations in 13 cases. 61
2226271 1990
37
Natural history of radiation-induced brachial plexopathy compared with surgically treated patients. 61
2391547 1990
38
Clinical and electrodiagnostic findings in breast cancer patients with radiation-induced brachial plexus neuropathy. 61
2327236 1990
39
Radiation-induced brachial plexus neuropathy in breast cancer patients. 61
2261203 1990
40
Distinction between neoplastic and radiation-induced brachial plexopathy, with emphasis on the role of EMG. 61
2538777 1989
41
The H-reflex of the flexor carpi radialis muscle; a study in controls and radiation-induced brachial plexus lesions. 61
6094729 1984
42
[Postradiotherapy brachial plexitis: the experience of the Institut Gustave-Roussy]. 61
6871488 1983

Variations for Radiation Induced Brachial Plexopathy

Expression for Radiation Induced Brachial Plexopathy

Search GEO for disease gene expression data for Radiation Induced Brachial Plexopathy.

Pathways for Radiation Induced Brachial Plexopathy

GO Terms for Radiation Induced Brachial Plexopathy

Sources for Radiation Induced Brachial Plexopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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