MCID: RDT005
MIFTS: 25

Radiation Induced Cancer

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Radiation Induced Cancer

MalaCards integrated aliases for Radiation Induced Cancer:

Name: Radiation Induced Cancer 53
Radiation-Induced Cancer 55 73
Radiation Related Cancer 53

Classifications:



External Ids:

UMLS 73 C0751366

Summaries for Radiation Induced Cancer

MalaCards based summary : Radiation Induced Cancer, also known as radiation-induced cancer, is related to thyroiditis and aging. An important gene associated with Radiation Induced Cancer is BRCA1 (BRCA1, DNA Repair Associated). The drugs Tamoxifen and Citric Acid have been mentioned in the context of this disorder. Affiliated tissues include skin, bone and thyroid.

Wikipedia : 76 Up to 10% of invasive cancers are related to radiation exposure, including both ionizing radiation and... more...

Related Diseases for Radiation Induced Cancer

Diseases related to Radiation Induced Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 thyroiditis 9.7
2 aging 9.7
3 sarcoma 9.6
4 prostatitis 9.6
5 squamous cell carcinoma 9.6
6 thyroid cancer 9.6
7 pigmented villonodular synovitis 9.6
8 synovitis 9.6
9 cockayne syndrome 9.6
10 testicular cancer 9.6
11 medulloblastoma 9.6
12 childhood medulloblastoma 9.6
13 small cell cancer of the lung 9.6
14 lung cancer 9.6
15 appendicitis 9.6
16 cystic fibrosis 9.6
17 villonodular synovitis 9.6
18 squamous cell carcinoma, head and neck 9.6
19 crohn's disease 9.6
20 lymphoma 9.6

Graphical network of the top 20 diseases related to Radiation Induced Cancer:



Diseases related to Radiation Induced Cancer

Symptoms & Phenotypes for Radiation Induced Cancer

Drugs & Therapeutics for Radiation Induced Cancer

Drugs for Radiation Induced Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 15)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tamoxifen Approved Phase 2 10540-29-1 2733526
2
Citric Acid Approved, Nutraceutical, Vet_approved Phase 2 77-92-9 311
3 Chelating Agents Phase 2
4 Selective Estrogen Receptor Modulators Phase 2
5 Hormone Antagonists Phase 2
6 Hormones Phase 2
7 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
8 Estrogen Antagonists Phase 2
9 Estrogen Receptor Modulators Phase 2
10 Estrogens Phase 2
11 Anticoagulants Phase 2
12 Bone Density Conservation Agents Phase 2
13 Calcium, Dietary Phase 2
14 Antineoplastic Agents, Hormonal Phase 2
15 Citrate Nutraceutical Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors Active, not recruiting NCT01196936 Phase 2 Tamoxifen Citrate;Placebo
2 Low Dose Effects of X-rays in Pediatric Patients Undergoing a CT Examination. Unknown status NCT01518673
3 The Incidence of Breast and Other Cancers Among Female Flight Attendants Completed NCT00342407
4 Cancer Risk in X-Ray Technologists: Second Survey Completed NCT00410475
5 Acute Abdominal Pain: Evaluation of Lactate Value as Predictive Factor of Surgical Issue Recruiting NCT03015233
6 Scientific Protocol for the Study of Leukemia and Other Hematologic Diseases Among Clean-up Workers in Ukraine Following the Chernobyl Accident Active, not recruiting NCT00341016

Search NIH Clinical Center for Radiation Induced Cancer

Genetic Tests for Radiation Induced Cancer

Anatomical Context for Radiation Induced Cancer

MalaCards organs/tissues related to Radiation Induced Cancer:

41
Skin, Bone, Thyroid, Lung, Testes, Liver, Prostate

Publications for Radiation Induced Cancer

Articles related to Radiation Induced Cancer:

(show top 50) (show all 101)
# Title Authors Year
1
Linarin inhibits radiation-induced cancer invasion by downregulating MMP-9 expression via the suppression of NF-I_B activation in human non-small-cell lung cancer A549. ( 29897257 )
2018
2
Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice. ( 28900036 )
2017
3
A novel mouse model of radiation-induced cancer survivorship diseases of the gut. ( 28729245 )
2017
4
Mathematical modelling of radiation-induced cancer risk from breast screening by mammography. ( 29103483 )
2017
5
Radiation-induced cancer risk predictions in proton and heavy ion radiotherapy. ( 28511776 )
2017
6
Comparative study of the calculated risk of radiation-induced cancer after photon- and proton-beam based radiosurgery of liver metastases. ( 28366554 )
2017
7
Epidemiological research on radiation-induced cancer in atomic bomb survivors. ( 26976124 )
2016
8
An extra copy of p53 suppresses development of spontaneous Kras-driven but not radiation-induced cancer. ( 27453951 )
2016
9
Organ-specific radiation-induced cancer risk estimates due to radiotherapy for benign pigmented villonodular synovitis. ( 27499236 )
2016
10
Non-targeted effects and radiation-induced cancer. ( 27893435 )
2016
11
Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer. ( 26880804 )
2016
12
Adjustment of lifetime risks of space radiation-induced cancer by the healthy worker effect and cancer misclassification. ( 27441231 )
2015
13
Radiotherapy for benign disease; assessing the risk of radiation-induced cancer following exposure to intermediate dose radiation. ( 26462717 )
2015
14
Do we Really Need a Program to Compensate Aviation Crewmembers for Radiation-Induced Cancer? ( 25905523 )
2015
15
ON THE ESTIMATION OF RADIATION-INDUCED CANCER RISKS FROM VERY LOW DOSES OF RADIATION AND HOW TO COMMUNICATE THESE RISKS. ( 25802468 )
2015
16
Concerning ionizing radiation-induced cancer from internally deposited radionuclides. ( 26063349 )
2015
17
Assessment of uncertainties in radiation-induced cancer risk predictions at clinically relevant doses. ( 25563249 )
2015
18
Communicating Potential Radiation-Induced Cancer Risks From Medical Imaging Directly to Patients. ( 26295534 )
2015
19
In vivo radioadaptive response: A review of studies relevant to radiation-induced cancer risk. ( 24925363 )
2014
20
Imaging for Appendicitis: Should Radiation-induced Cancer Risks Affect Modality Selection? ( 24988435 )
2014
21
Cancer risk from low dose radiation depends directly on the organ mass in a general model of radiation-induced cancer risk. ( 24562066 )
2014
22
Don't let radiation scare trump patient care: 10 ways you can harm your patients by fear of radiation-induced cancer from diagnostic imaging. ( 24764114 )
2014
23
Curbing potential radiation-induced cancer risks in oncologic imaging: perspectives from the 'image gently' and 'image wisely' campaigns. ( 24855732 )
2014
24
Estimated risk of radiation-induced cancer following paediatric cranio-spinal irradiation with electron, photon and proton therapy. ( 25017376 )
2014
25
Estimated risk of radiation-induced cancer from paediatric chest CT: two-year cohort study. ( 25274469 )
2014
26
How is the risk of radiation-induced cancer influenced by background risk factors? Invited commentary on "a method for determining weights for excess relative risk and excess absolute risk when applied in the calculation of lifetime risk of cancer from radiation exposure" by Walsh and Schneider (2012). ( 23180111 )
2013
27
Body CT scanning in young adults: examination indications, patient outcomes, and risk of radiation-induced cancer. ( 23386731 )
2013
28
Patients with testicular cancer undergoing CT surveillance demonstrate a pitfall of radiation-induced cancer risk estimates: the timing paradox. ( 23249573 )
2013
29
Cost-effectiveness of imaging strategies to reduce radiation-induced cancer risk in Crohn's disease. ( 21928375 )
2012
30
Radiation-induced cancer: a modern view. ( 23175483 )
2012
31
Frequent body CT scanning of young adults: indications, outcomes, and risk for radiation-induced cancer. ( 21723488 )
2011
32
A new view of radiation-induced cancer. ( 21113062 )
2011
33
Radiation induced cancer arises from a somatic mutation. ( 21346281 )
2011
34
Radiation-induced cancer cell repopulation: a possible mechanism implied by experiments using transplantable mouse-derived sarcoma cell line. ( 21206131 )
2011
35
Neoplastic transformation in vitro: is it a valid assay or not for assessing the shape of the dose-response curve for radiation-induced cancer in vivo? ( 21595075 )
2011
36
Meta-analysis of non-tumour doses for radiation-induced cancer on the basis of dose-rate. ( 21250929 )
2011
37
Scientific approach to radiation-induced cancer risk. ( 22353659 )
2011
38
Latency period of radiation-induced cancer. ( 22106106 )
2011
39
Epidemiology of radiation-induced cancer. ( 21285730 )
2011
40
Comparison of radiation exposure and associated radiation-induced cancer risks from mammography and molecular imaging of the breast. ( 21302775 )
2010
41
Recurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adults. ( 19332852 )
2009
42
A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation. ( 19499238 )
2009
43
Extrapolating radiation-induced cancer risks from low doses to very low doses. ( 19820460 )
2009
44
A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: approach. ( 19536557 )
2009
45
Mechanistic model of radiation-induced cancer after fractionated radiotherapy using the linear-quadratic formula. ( 19472619 )
2009
46
Radiation-induced cancer after radiotherapy for non-Hodgkin's lymphoma of the head and neck: a retrospective study. ( 19591686 )
2009
47
Low-dose lung computed tomography screening before age 55: estimates of the mortality reduction required to outweigh the radiation-induced cancer risk. ( 18927099 )
2008
48
Systems biological and mechanistic modelling of radiation-induced cancer. ( 18097677 )
2008
49
Radiation-induced cancer risk from annual computed tomography for patients with cystic fibrosis. ( 17717201 )
2007
50
Monte Carlo determination of radiation-induced cancer risks for prostate patients undergoing intensity- modulated radiation therapy. ( 18449157 )
2007

Variations for Radiation Induced Cancer

Expression for Radiation Induced Cancer

Search GEO for disease gene expression data for Radiation Induced Cancer.

Pathways for Radiation Induced Cancer

GO Terms for Radiation Induced Cancer

Sources for Radiation Induced Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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