MCID: RDT005
MIFTS: 25

Radiation Induced Cancer

Categories: Cancer diseases, Rare diseases, Skin diseases

Aliases & Classifications for Radiation Induced Cancer

MalaCards integrated aliases for Radiation Induced Cancer:

Name: Radiation Induced Cancer 53
Radiation-Induced Cancer 55 73
Radiation Related Cancer 53

Classifications:



External Ids:

UMLS 73 C0751366

Summaries for Radiation Induced Cancer

MalaCards based summary : Radiation Induced Cancer, also known as radiation-induced cancer, is related to medulloblastoma and small cell cancer of the lung. An important gene associated with Radiation Induced Cancer is BRCA1 (BRCA1, DNA Repair Associated). The drugs Tamoxifen and Citric Acid have been mentioned in the context of this disorder. Affiliated tissues include skin, lung and bone.

Wikipedia : 76 Up to 10% of invasive cancers are related to radiation exposure, including both ionizing radiation and... more...

Related Diseases for Radiation Induced Cancer

Diseases related to Radiation Induced Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 medulloblastoma 9.7
2 small cell cancer of the lung 9.7
3 lung cancer 9.7
4 cystic fibrosis 9.7
5 squamous cell carcinoma, head and neck 9.7
6 crohn's disease 9.7
7 lymphoma 9.7
8 sarcoma 9.7
9 squamous cell carcinoma 9.7
10 pigmented villonodular synovitis 9.7
11 synovitis 9.7
12 cockayne syndrome 9.7
13 testicular cancer 9.7
14 childhood medulloblastoma 9.7
15 appendicitis 9.7
16 villonodular synovitis 9.7

Graphical network of the top 20 diseases related to Radiation Induced Cancer:



Diseases related to Radiation Induced Cancer

Symptoms & Phenotypes for Radiation Induced Cancer

Drugs & Therapeutics for Radiation Induced Cancer

Drugs for Radiation Induced Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tamoxifen Approved Phase 2 10540-29-1 2733526
2
Citric Acid Approved, Nutraceutical, Vet_approved Phase 2 77-92-9 311
3 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
4 Antineoplastic Agents, Hormonal Phase 2
5 Estrogens Phase 2
6 Estrogen Receptor Antagonists Phase 2
7 Selective Estrogen Receptor Modulators Phase 2
8 Estrogen Antagonists Phase 2
9 Anticoagulants Phase 2
10 Chelating Agents Phase 2
11 Citrate Phase 2
12 Hormones Phase 2
13 Calcium, Dietary Phase 2
14 Estrogen Receptor Modulators Phase 2
15 Bone Density Conservation Agents Phase 2
16 Hormone Antagonists Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Low-Dose Tamoxifen Citrate in Reducing Breast Cancer Risk in Radiation-Induced Cancer Survivors Active, not recruiting NCT01196936 Phase 2 Tamoxifen Citrate;Placebo
2 Low Dose Effects of X-rays in Pediatric Patients Undergoing a CT Examination. Unknown status NCT01518673
3 Acute Abdominal Pain: Evaluation of Lactate Value as Predictive Factor of Surgical Issue Unknown status NCT03015233
4 The Incidence of Breast and Other Cancers Among Female Flight Attendants Completed NCT00342407
5 Cancer Risk in X-Ray Technologists: Second Survey Completed NCT00410475
6 Scientific Protocol for the Study of Leukemia and Other Hematologic Diseases Among Clean-up Workers in Ukraine Following the Chernobyl Accident Active, not recruiting NCT00341016

Search NIH Clinical Center for Radiation Induced Cancer

Genetic Tests for Radiation Induced Cancer

Anatomical Context for Radiation Induced Cancer

MalaCards organs/tissues related to Radiation Induced Cancer:

41
Skin, Lung, Bone, Thyroid, Brain, Liver, Prostate

Publications for Radiation Induced Cancer

Articles related to Radiation Induced Cancer:

(show top 50) (show all 104)
# Title Authors Year
1
Linarin inhibits radiation-induced cancer invasion by downregulating MMP-9 expression via the suppression of NF-I_B activation in human non-small-cell lung cancer A549. ( 29897257 )
2018
2
Out-of-field doses from secondary radiation produced in proton therapy and the associated risk of radiation-induced cancer from a brain tumor treatment. ( 30241747 )
2018
3
Cohort Profile: the EPI-CT study: A European pooled epidemiological study to quantify the risk of radiation-induced cancer from paediatric CT. ( 30388267 )
2018
4
Proton radiation-induced cancer progression. ( 30482279 )
2018
5
Polo-like kinase 1 (Plk1) overexpression enhances ionizing radiation-induced cancer formation in mice. ( 28900036 )
2017
6
A novel mouse model of radiation-induced cancer survivorship diseases of the gut. ( 28729245 )
2017
7
Mathematical modelling of radiation-induced cancer risk from breast screening by mammography. ( 29103483 )
2017
8
Radiation-induced cancer risk predictions in proton and heavy ion radiotherapy. ( 28511776 )
2017
9
Comparative study of the calculated risk of radiation-induced cancer after photon- and proton-beam based radiosurgery of liver metastases. ( 28366554 )
2017
10
Epidemiological research on radiation-induced cancer in atomic bomb survivors. ( 26976124 )
2016
11
An extra copy of p53 suppresses development of spontaneous Kras-driven but not radiation-induced cancer. ( 27453951 )
2016
12
Organ-specific radiation-induced cancer risk estimates due to radiotherapy for benign pigmented villonodular synovitis. ( 27499236 )
2016
13
Non-targeted effects and radiation-induced cancer. ( 27893435 )
2016
14
Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer. ( 26880804 )
2016
15
Adjustment of lifetime risks of space radiation-induced cancer by the healthy worker effect and cancer misclassification. ( 27441231 )
2015
16
Radiotherapy for benign disease; assessing the risk of radiation-induced cancer following exposure to intermediate dose radiation. ( 26462717 )
2015
17
Do we Really Need a Program to Compensate Aviation Crewmembers for Radiation-Induced Cancer? ( 25905523 )
2015
18
ON THE ESTIMATION OF RADIATION-INDUCED CANCER RISKS FROM VERY LOW DOSES OF RADIATION AND HOW TO COMMUNICATE THESE RISKS. ( 25802468 )
2015
19
Concerning ionizing radiation-induced cancer from internally deposited radionuclides. ( 26063349 )
2015
20
Assessment of uncertainties in radiation-induced cancer risk predictions at clinically relevant doses. ( 25563249 )
2015
21
Communicating Potential Radiation-Induced Cancer Risks From Medical Imaging Directly to Patients. ( 26295534 )
2015
22
In vivo radioadaptive response: A review of studies relevant to radiation-induced cancer risk. ( 24925363 )
2014
23
Imaging for Appendicitis: Should Radiation-induced Cancer Risks Affect Modality Selection? ( 24988435 )
2014
24
Cancer risk from low dose radiation depends directly on the organ mass in a general model of radiation-induced cancer risk. ( 24562066 )
2014
25
Don't let radiation scare trump patient care: 10 ways you can harm your patients by fear of radiation-induced cancer from diagnostic imaging. ( 24764114 )
2014
26
Curbing potential radiation-induced cancer risks in oncologic imaging: perspectives from the 'image gently' and 'image wisely' campaigns. ( 24855732 )
2014
27
Estimated risk of radiation-induced cancer following paediatric cranio-spinal irradiation with electron, photon and proton therapy. ( 25017376 )
2014
28
Estimated risk of radiation-induced cancer from paediatric chest CT: two-year cohort study. ( 25274469 )
2014
29
How is the risk of radiation-induced cancer influenced by background risk factors? Invited commentary on "a method for determining weights for excess relative risk and excess absolute risk when applied in the calculation of lifetime risk of cancer from radiation exposure" by Walsh and Schneider (2012). ( 23180111 )
2013
30
Body CT scanning in young adults: examination indications, patient outcomes, and risk of radiation-induced cancer. ( 23386731 )
2013
31
Patients with testicular cancer undergoing CT surveillance demonstrate a pitfall of radiation-induced cancer risk estimates: the timing paradox. ( 23249573 )
2013
32
Cost-effectiveness of imaging strategies to reduce radiation-induced cancer risk in Crohn's disease. ( 21928375 )
2012
33
Radiation-induced cancer: a modern view. ( 23175483 )
2012
34
Frequent body CT scanning of young adults: indications, outcomes, and risk for radiation-induced cancer. ( 21723488 )
2011
35
A new view of radiation-induced cancer. ( 21113062 )
2011
36
Radiation induced cancer arises from a somatic mutation. ( 21346281 )
2011
37
Radiation-induced cancer cell repopulation: a possible mechanism implied by experiments using transplantable mouse-derived sarcoma cell line. ( 21206131 )
2011
38
Neoplastic transformation in vitro: is it a valid assay or not for assessing the shape of the dose-response curve for radiation-induced cancer in vivo? ( 21595075 )
2011
39
Meta-analysis of non-tumour doses for radiation-induced cancer on the basis of dose-rate. ( 21250929 )
2011
40
Scientific approach to radiation-induced cancer risk. ( 22353659 )
2011
41
Latency period of radiation-induced cancer. ( 22106106 )
2011
42
Epidemiology of radiation-induced cancer. ( 21285730 )
2011
43
Reply to comment on ‘Radiation induced cancer arises from a somatic mutation’. ( 21970023 )
2011
44
Comparison of radiation exposure and associated radiation-induced cancer risks from mammography and molecular imaging of the breast. ( 21302775 )
2010
45
Recurrent CT, cumulative radiation exposure, and associated radiation-induced cancer risks from CT of adults. ( 19332852 )
2009
46
A new view of radiation-induced cancer: integrating short- and long-term processes. Part II: second cancer risk estimation. ( 19499238 )
2009
47
Extrapolating radiation-induced cancer risks from low doses to very low doses. ( 19820460 )
2009
48
A new view of radiation-induced cancer: integrating short- and long-term processes. Part I: approach. ( 19536557 )
2009
49
Mechanistic model of radiation-induced cancer after fractionated radiotherapy using the linear-quadratic formula. ( 19472619 )
2009
50
Radiation-induced cancer after radiotherapy for non-Hodgkin's lymphoma of the head and neck: a retrospective study. ( 19591686 )
2009

Variations for Radiation Induced Cancer

Expression for Radiation Induced Cancer

Search GEO for disease gene expression data for Radiation Induced Cancer.

Pathways for Radiation Induced Cancer

GO Terms for Radiation Induced Cancer

Sources for Radiation Induced Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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