Aliases & Classifications for Radiculopathy

MalaCards integrated aliases for Radiculopathy:

Name: Radiculopathy 12 44 15 73
Nerve Root Disorder 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4306
ICD10 33 M54.1 M54.10
MeSH 44 D011843
SNOMED-CT 68 394640000 72274001

Summaries for Radiculopathy

MalaCards based summary : Radiculopathy, also known as nerve root disorder, is related to meningitis and lymphadenitis, and has symptoms including neuralgia An important gene associated with Radiculopathy is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Dexamethasone and Acetaminophen have been mentioned in the context of this disorder. Affiliated tissues include bone, testes and spinal cord, and related phenotypes are Synthetic lethal with MLN4924 (a NAE inhibitor) and Synthetic lethal with MLN4924 (a NAE inhibitor)

Wikipedia : 76 Radiculopathy, also commonly referred to as pinched nerve, refers to a set of conditions in which one or... more...

Related Diseases for Radiculopathy

Diseases related to Radiculopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 319)
# Related Disease Score Top Affiliating Genes
1 meningitis 29.5 CXCL8 IL10 IL6
2 lymphadenitis 29.1 CXCL8 CXCR3 IL10
3 polyradiculoneuropathy 29.0 CCL5 IL10 IL17A
4 arthritis 28.6 CXCL8 IL10 IL17A IL1A IL6
5 rheumatoid arthritis 25.8 CCL5 CXCL8 IL10 IL17A IL1A IL1R1
6 polyradiculopathy 10.9
7 pinched nerve 10.9
8 cervicitis 10.7
9 cryopyrin-associated periodic syndrome 10.7 IL1R1 IL6
10 eye lymphoma 10.7 IL10 IL6
11 cutaneous candidiasis 10.7 IL17A IL2RA
12 anterior uveitis 10.6 IL2RA IL6
13 paratyphoid fever 10.6 IL1A IL1R1
14 hyperlucent lung 10.6 IL10 IL2RA
15 autoimmune enteropathy 10.6 IL17A IL2RA
16 viral pneumonia 10.6 IL17A IL6
17 b-cell growth factor 10.6 IL6 IL7
18 angioimmunoblastic lymphadenopathy with dysproteinemia 10.6 IL5 IL6
19 rheumatoid arthritis, systemic juvenile 10.5 IL1R1 IL6
20 transient arthritis 10.5 IL1A IL6
21 joint disorders 10.5 IL17A IL1R1 IL6
22 stromal keratitis 10.5 IL17A IL2RA IL6
23 keratoconjunctivitis sicca 10.5 IL10 IL1A IL6
24 extrinsic cardiomyopathy 10.5 IL10 IL17A IL6
25 recurrent corneal erosion 10.4 CXCL8 IL6
26 graft-versus-host disease 10.4 IL10 IL1A IL6
27 spondyloarthropathy 10.4 IL10 IL17A IL6
28 primary bacterial infectious disease 10.4 IL10 IL17A IL6
29 pertussis 10.4 IL10 IL1A IL6
30 central nervous system vasculitis 10.4 IL17A IL6
31 juvenile rheumatoid arthritis 10.4 IL1R1 IL2RA IL6
32 chronic graft versus host disease 10.4 IL10 IL1A IL2RA
33 psoriatic arthritis 10.4 IL17A IL1A IL6
34 streptococcal toxic-shock syndrome 10.4 CXCL8 IL6
35 leukoregulin 10.4 CXCL8 IL1A
36 acute generalized exanthematous pustulosis 10.4 CXCL8 IL17A
37 vogt-koyanagi-harada disease 10.3 IL10 IL17A IL2RA
38 denture stomatitis 10.3 CXCL8 IL6
39 connective tissue disease 10.3 IL10 IL1A IL6
40 cow milk allergy 10.3 IL10 IL5
41 back pain 10.3
42 rheumatic disease 10.3 IL10 IL1R1 IL2RA
43 tungiasis 10.3 CXCL8 IL10
44 scorpion envenomation 10.2 CCL5 IL6
45 apple allergy 10.2 IL10 IL5
46 paragonimiasis 10.2 CXCR3 IL5
47 multicentric castleman disease 10.2 IL10 IL5 IL6
48 pulpitis 10.2 CXCL8 IL1A IL6
49 pouchitis 10.2 CXCL8 IL10
50 capillary leak syndrome 10.2 CXCL8 IL6

Graphical network of the top 20 diseases related to Radiculopathy:



Diseases related to Radiculopathy

Symptoms & Phenotypes for Radiculopathy

UMLS symptoms related to Radiculopathy:


neuralgia

GenomeRNAi Phenotypes related to Radiculopathy according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-1 9.36 CXCL8 IL10 IL17A IL1A IL2RA
2 Synthetic lethal with MLN4924 (a NAE inhibitor) GR00250-A-2 9.36 AVPR2 CXCL8 IL10 IL17A IL1A IL2RA

MGI Mouse Phenotypes related to Radiculopathy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 10.06 IL1R1 AVPR2 IL2RA CCL5 CXCR3 IL5
2 homeostasis/metabolism MP:0005376 9.96 PENK IL1A IL1R1 AVPR2 IL2RA CXCR3
3 endocrine/exocrine gland MP:0005379 9.91 PENK IL1R1 IL2RA IL10 IL6 IL17A
4 immune system MP:0005387 9.85 IL1A IL1R1 IL2RA CCL5 CXCR3 IL5
5 neoplasm MP:0002006 9.43 IL1A IL1R1 CXCR3 IL5 IL10 IL6
6 respiratory system MP:0005388 9.17 IL1R1 IL2RA CXCR3 IL5 IL10 IL6

Drugs & Therapeutics for Radiculopathy

Drugs for Radiculopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 180)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable 50-02-2 5743
2
Acetaminophen Approved Phase 4,Phase 3,Not Applicable 103-90-2 1983
3
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 137-58-6 3676
4
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 2180-92-9, 38396-39-3 2474
5
Meloxicam Approved, Vet_approved Phase 4,Not Applicable 71125-38-7 5281106 54677470
6
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Not Applicable 148553-50-8 5486971
7
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Not Applicable 124-94-7 31307
8
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3 76-42-6 5284603
9
Milnacipran Approved, Investigational Phase 4 92623-85-3 65833
10
Betamethasone Approved, Vet_approved Phase 4,Phase 2,Not Applicable 378-44-9 9782
11
Ibuprofen Approved Phase 4 15687-27-1 3672
12
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
13
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
14
Eplerenone Approved Phase 4 107724-20-9 150310 443872
15
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
16 Dexamethasone acetate Phase 4,Phase 2,Phase 1,Not Applicable 1177-87-3
17 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
19
protease inhibitors Phase 4,Phase 2,Phase 1,Not Applicable
20 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
21 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
22 HIV Protease Inhibitors Phase 4,Phase 2,Phase 1,Not Applicable
23 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
24 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
25 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
26 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
27 Antiemetics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
28 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
29 Antipyretics Phase 4,Not Applicable
30 BB 1101 Phase 4,Phase 2,Phase 1,Not Applicable
31 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
32 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
33 triamcinolone acetonide Phase 4,Phase 3,Not Applicable
34 Betamethasone Valerate Phase 4,Phase 2,Not Applicable 2152-44-5
35 calcium channel blockers Phase 4,Phase 3,Not Applicable
36 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
37 Adrenergic Agents Phase 4,Phase 3,Phase 2,Not Applicable
38 Serotonin Agents Phase 4
39 Serotonin Uptake Inhibitors Phase 4
40 Sodium Channel Blockers Phase 4,Phase 1,Not Applicable
41 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
42 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2,Not Applicable
43 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2,Not Applicable
44 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
45 Anesthetics, Local Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
46 Tranquilizing Agents Phase 4,Phase 3,Not Applicable
47 Triamcinolone diacetate Phase 4,Phase 3,Not Applicable
48 Triamcinolone hexacetonide Phase 4,Phase 3,Not Applicable
49 Diuretics, Potassium Sparing Phase 4,Phase 1,Not Applicable
50 Anti-Anxiety Agents Phase 4,Phase 3,Not Applicable

Interventional clinical trials:

(show top 50) (show all 196)
# Name Status NCT ID Phase Drugs
1 A Post-marketing Evaluation of a Compound Traditional Chinese Herbal Medicine, Qishe Pill, on Cervical Radiculopathy Unknown status NCT01875562 Phase 4 Qishe Pill
2 Conservative Versus Aggressive Discectomy for Primary Disc Herniation With Radiculopathy Unknown status NCT01204008 Phase 4
3 Comparison of the Efficacy of rTMS and tDCS of the Motor Cortex in Patients With Chronic Neuropathic Pain Completed NCT02030626 Phase 4
4 Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level Completed NCT00554528 Phase 4
5 Caudal Epidural Steroid Injections for Low Back Pain/Sciatic Lumbar Pain Completed NCT01407913 Phase 4
6 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4 Pregabalin
7 Milnacipran for Lumbosacral Radicular Pain Completed NCT01777581 Phase 4 Milnacipran;Placebo
8 High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System Completed NCT02265848 Phase 4
9 Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™ Completed NCT01615328 Phase 4
10 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4 Triamcinolone 80mg
11 Efficacy of Pregabalin in Patients With Radicular Pain Completed NCT00908375 Phase 4 Pregabalin;Sugar Pill
12 Pentoxifylline and Lumbar Radiculopathy Recruiting NCT03060434 Phase 4 Pentoxifylline Oral Tablet;Ibuprofen
13 Percutaneous HydroDiscectomy Compared to TESI for Radiculopathy Recruiting NCT02414698 Phase 4 TESI
14 A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Recruiting NCT03514277 Phase 4 Exparel;Bupivacaine
15 Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness? Not yet recruiting NCT03382925 Phase 4 Lidocaine;Triamcinolone Acetonide;Normal saline
16 Comparative Trial Via Tranforaminal Approach Versus Epidural Catheter Via Interlaminar Approach Not yet recruiting NCT03382821 Phase 4 Dexamethasone Sodium Phosphate 10 MG/ML;Lidocaine;Triamcinolone Acetonide 40mg/mL
17 Cervical Interlaminar Versus Transforaminal Epidural Steroid Injection Not yet recruiting NCT03165825 Phase 4 Transforaminal Epidural Steroid Injection with Dexamethasone;Interlaminar Epidural Steroid Injection with Betamethasone
18 Eplerenone as a Supplement to Epidural Steroid Injections Not yet recruiting NCT03418649 Phase 4 Eplerenone 50 Mg Tab;Placebo Oral Tablet
19 Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness Not yet recruiting NCT03127137 Phase 4 Experimental Group 1 triamcinolone and lidocaine;Experimental Group 2 triamcinolone and saline
20 Transforaminal Epidural Steroid Injection With Pulsed Radiofrequency for Chronic Lumbosacral Radicular Pain Management Not yet recruiting NCT02930057 Phase 4 Celestone;Control
21 CT Guided Injection for Low Back Radiculopathy: A Randomized Clinical Trial Terminated NCT01267825 Phase 4 CT-guided corticosteroid+ bupivicaine;Standard medical care
22 Spinal Cord Stimulation for Chronic and Intractable Back Pain Terminated NCT00370695 Phase 4
23 Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis Withdrawn NCT03245671 Phase 4 Kenalog Injectable Product;Decadron Phosphate, Injectable
24 Safety and Efficacy of Neuromultivit in Treatment of Vertebrogenic Radiculopathy Completed NCT02508805 Phase 3 Neuromultivit;Voltaren;Sirdalud
25 Study to Evaluate the Efficacy and Safety of Lenalidomide in the Treatment of Painful Lumbar Radiculopathy Completed NCT00120120 Phase 2, Phase 3 Lenalidomide (CC-5013)
26 Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy Completed NCT00159705 Phase 3 pregabalin
27 A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy Completed NCT00733096 Phase 2, Phase 3 etanercept;methylprednisolone;normal saline
28 The Value of Traction in Treatment of Lumbar Radiculopathy Completed NCT00942227 Phase 3
29 The Value of Traction in the Treatment of Cervical Radiculopathy Completed NCT00979108 Phase 3
30 The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery Completed NCT01073995 Phase 3 Kenalog and Sensorcaine
31 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
32 Physiotherapy for Sciatica; Is Earlier Better? Completed NCT02618278 Phase 3
33 PCM Cervical Disc System Completed NCT00578812 Phase 3
34 Immediate Pain Relieving Effects of Sinbaro-3 for Low Back Pain Completed NCT02196129 Phase 3 Sinbaro-3;Hwangryun
35 Efficacy and Safety of Ralfinamide in Patients With Chronic Neuropathic Low Back Pain Completed NCT01019824 Phase 3 Ralfinamide
36 The Efficacy of Oral Steroids in the Treatment of Acute Sciatica Completed NCT00317447 Phase 3 Oral Prednisone
37 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
38 Manual Physical Therapy and Exercise for Mechanical Neck Disorders Completed NCT00416117 Phase 2, Phase 3
39 NUCYNTA (Tapentadol Immediate Release) Versus Oxycodone Immediate Release in the Treatment of Acute Low Back Pain Completed NCT00986180 Phase 3 NUCYNTA;Oxycodone IR
40 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy Recruiting NCT03372161 Phase 3 SP-102;Placebo
41 Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine Recruiting NCT03386149 Phase 3 Bosinji;Loxonine tab.
42 Surgery Versus Standardized Non-operative Care for the Treatment of Lumbar Disc Herniations: A Canadian Trial Recruiting NCT01335646 Phase 3
43 Pilot Study of Orphenadrine` in the Treatment of Muscle Cramps in Patients With Cirrhosis Recruiting NCT02423395 Phase 3 orphenadrine;Placebo
44 Restore CLINICAL TRIAL Active, not recruiting NCT01609374 Phase 3
45 Twice Daily Oral ALLOD-2 vs. Placebo in the Treatment of Chronic Low Back Pain (ANODYNE-4) Active, not recruiting NCT03201393 Phase 2, Phase 3 ALLOD-2 Capsules;Placebo Capsules
46 Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion Not yet recruiting NCT03327272 Phase 3 Methylprednisolone;Saline
47 Lumbar Transforaminal Epidural Corticosteroid Injection(s) Versus Defined Physical Therapy Terminated NCT01443819 Phase 3
48 INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine Terminated NCT01415908 Phase 3
49 Qishe Pill for Cervical Radiculopathy Unknown status NCT01274936 Phase 2 Qishe Pill;Qishe Placebo
50 Study of REN-1654 in Patients With Sciatica Pain Unknown status NCT00107055 Phase 2 REN-1654

Search NIH Clinical Center for Radiculopathy

Cochrane evidence based reviews: radiculopathy

Genetic Tests for Radiculopathy

Anatomical Context for Radiculopathy

MalaCards organs/tissues related to Radiculopathy:

41
Bone, Testes, Spinal Cord, Brain, Dorsal Root Ganglion, Myeloid, Bone Marrow

Publications for Radiculopathy

Articles related to Radiculopathy:

(show top 50) (show all 723)
# Title Authors Year
1
The efficacy of cauda epidural steroid injections with targeted indwelling catheter and manipulation in managing patients with lumbar disc herniation with radiculopathy: a prospective, randomized, single-blind controlled trial. ( 29410375 )
2018
2
The Effect of Pregabalin and Metformin on Subacute and Chronic Radiculopathy. ( 29531924 )
2018
3
A novel noninstrumented surgical approach for foramen reconstruction for isthmic spondylolisthesis in patients with radiculopathy: preliminary clinical and radiographic outcomes. ( 29290136 )
2018
4
Calf muscle hypertrophy following S1 radiculopathy: A stress disorder caused by hyperactivity with variable response to treatmen. ( 29451471 )
2018
5
The effectiveness of therapeutic strategies for patients with radiculopathy: A network meta-analysis. ( 29651898 )
2018
6
An awake, minimally-invasive, fully-endoscopic surgical technique for treating lumbar radiculopathy secondary to heterotopic foraminal bone formation after a minimally invasive transforaminal lumbar interbody fusion with BMP: technical note. ( 29732437 )
2018
7
Return to work following surgery for lumbar radiculopathy: a systematic review. ( 29800705 )
2018
8
Comparison between cervical disc arthroplasty and conservative treatment for patients with single level cervical radiculopathy at C5/6. ( 29409935 )
2018
9
Sensitivity and Specificity of Modified Bragard Test in Patients With Lumbosacral Radiculopathy Using Electrodiagnosis as a Reference Standard. ( 29628807 )
2018
10
The impact of mental health on patient-reported outcomes in cervical radiculopathy or myelopathy surgery. ( 29907392 )
2018
11
Salvage of cervical motor radiculopathy using peripheral nerve transfer reconstruction. ( 29745256 )
2018
12
Correction to: Minimally invasive posterior cervical foraminotomy for treatment of radiculopathy : An effective, time-tested, and cost-efficient motion-preservation technique. ( 29270676 )
2018
13
A case report: C2 radiculopathy induced by neck flexion due to the cord compression of C2 segmental type vertebral artery relieved by microvascular decompression. ( 29900031 )
2018
14
Extra-Osseous Ewing Sarcoma of Sciatic Nerve Masquerading as Benign Nerve Sheath Tumor and Presented as Lumbar Radiculopathy: Case Report and Review of Literature. ( 29673820 )
2018
15
Investigation of the effectiveness of therapeutic ultrasound with high-resolution ultrasonographic cross-sectional area measurement of cervical nerve roots in patients with chronic cervical radiculopathy: a prospective, controlled, single-blind study. ( 29318418 )
2018
16
Sacral Myeloid Sarcoma Manifesting as Radiculopathy in a Pediatric Patient: An Unusual Form of Myeloid Leukemia Relapse. ( 29888021 )
2018
17
Posterior percutaneous full-endoscopic cervical discectomy under local anesthesia for cervical radiculopathy due to soft-disc herniation: a preliminary clinical study. ( 29957146 )
2018
18
Non-Small Cell Lung Cancer Drop Metastasis Causing Lumbosacral Radiculopathy. ( 29878259 )
2018
19
Cervical radiculopathy and cervical myelopathy: diagnosis and management in primary care. ( 29284641 )
2018
20
Cervical Radiculopathy: Effectiveness of Adding Traction to Physical Therapy. A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ( 29315428 )
2018
21
Energy Impairments in Older Adults With Low Back Pain and Radiculopathy: A Matched Case-Control Study. ( 29698638 )
2018
22
Minimally Invasive Transtubular Endoscopic Decompression for L5 Radiculopathy Induced by Lumbosacral Extraforaminal Lesions. ( 29713405 )
2018
23
Complications of Full-Endoscopic Versus Microendoscopic Foraminotomy for Cervical Radiculopathy: A Systematic Review and Meta-Analysis. ( 29602008 )
2018
24
N-Palmitoyl Ethanol Amide Pharmacological Treatment in Patients With Nonsurgical Lumbar Radiculopathy. ( 29364513 )
2018
25
Painless motor radiculopathy of the cervical spine: clinical and radiological characteristics and long-term outcomes after operative decompression. ( 29570047 )
2018
26
Contralateral radiculopathy after transforaminal lumbar interbody fusion in the treatment of lumbar degenerative diseases: A Case Series. ( 29668622 )
2018
27
Comparison of Anterior Cervical Discectomy and Fusion to Posterior Cervical Foraminotomy for Cervical Radiculopathy: Utilization, Costs and Adverse Events 2003 to 2014. ( 29548034 )
2018
28
Factors related to subjective satisfaction following microendoscopic foraminotomy for cervical radiculopathy. ( 29361919 )
2018
29
Apparent C8-T1 radiculopathy with hand weakness due to mid-cervical spondylosis. ( 29097135 )
2018
30
Immediate and lasting effects of a thoracic spine manipulation in a patient with signs of cervical radiculopathy and upper extremity hyperalgesia: A case report. ( 27911127 )
2017
31
Asymmetric Atrophy of Paraspinal Muscles in Patients With Chronic Unilateral Lumbar Radiculopathy. ( 29201819 )
2017
32
A Rare Case of T1-2 Thoracic Disc Herniation Mimicking Cervical Radiculopathy. ( 29372134 )
2017
33
Ultrasonography has a diagnostic value in the assessment of cervical radiculopathy: A prospective pilot study. ( 28050690 )
2017
34
Minimally invasive posterior cervical foraminotomy for treatment of radiculopathy : An effective, time-tested, and cost-efficient motion-preservation technique. ( 28929274 )
2017
35
Posterior cervical transfacet fusion with facetal spacer for the treatment of single-level cervical radiculopathy: a randomized controlled prospective study. ( 28065872 )
2017
36
Neuroprotective Potential of Gentongping in Rat Model of Cervical Spondylotic Radiculopathy Targeting PPAR-<i>I^</i>Pathway. ( 29230425 )
2017
37
Epidural Injections Contraindicated for Lumbar Radiculopathy in May-Thurner Syndrome: A Case Report. ( 28697031 )
2017
38
Surgical and Functional Outcomes After Multilevel Cervical Fusion for Degenerative Disc Disease Compared With Fusion for Radiculopathy: A Study of Workers' Compensation Population. ( 28441686 )
2017
39
Comparison of Root Images between Post-Myelographic Computed Tomography and Magnetic Resonance Imaging in Patients with Lumbar Radiculopathy. ( 28881117 )
2017
40
Risk factor of contralateral radiculopathy following microendoscopy-assisted minimally invasive transforaminal lumbar interbody fusion. ( 29222690 )
2017
41
Early outcomes of endoscopic contralateral foraminal and lateral recess decompression via an interlaminar approach in patients with unilateral radiculopathy from unilateral foraminal stenosis. ( 28919229 )
2017
42
The Clinical Comparison Between the Patients Operated for Unilateral Radiculopathy Via Contralateral(Facet-Sparing)and Ipsilateral Side Approach. ( 28770554 )
2017
43
Shi-style cervical manipulations for cervical radiculopathy: A multicenter randomized-controlled clinical trial. ( 28767566 )
2017
44
Particulate versus non-particulate corticosteroids for transforaminal nerve root blocks: Comparison of outcomes in 494 patients with lumbar radiculopathy. ( 28894933 )
2017
45
Recovery of H-Reflex with Transforaminal Epidural Steroid Injection in S1 Radiculopathy. ( 28087843 )
2017
46
Comparison of Symptoms From C6 and C7 Radiculopathy. ( 28767636 )
2017
47
Focal myositis associated to radiculopathy. ( 28629659 )
2017
48
The Risks of Hepatitis C in Association With Cervical Spinal Surgery: Analysis of Radiculopathy and Myelopathy Patients. ( 29293101 )
2017
49
A case of cervical radiculopathy due to tuberculosis cervical lymphadenitis. ( 29620071 )
2017
50
A comparison of H-reflex in the triceps surae muscle group in patients with S1 radiculopathy. ( 29307252 )
2017

Variations for Radiculopathy

Expression for Radiculopathy

Search GEO for disease gene expression data for Radiculopathy.

Pathways for Radiculopathy

Pathways related to Radiculopathy according to GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.94 CCL5 CXCL8 IL10 IL17A IL1A IL1R1
2
Show member pathways
13.76 CCL5 CXCL8 CXCR3 IL10 IL17A IL1A
3
Show member pathways
13.6 CCL5 CXCL8 CXCR3 IL10 IL17A IL1A
4
Show member pathways
13.38 CCL5 CXCL8 IL10 IL17A IL1A IL1R1
5
Show member pathways
13.3 CCL5 CXCL8 IL10 IL17A IL1A IL1R1
6
Show member pathways
13.18 CCL5 CXCL8 CXCR3 IL10 IL17A IL1A
7
Show member pathways
12.86 CXCL8 IL10 IL17A IL1A IL2RA IL5
8 12.8 CXCL8 IL2RA IL5 IL6 IL7
9
Show member pathways
12.8 CCL5 CXCL8 CXCR3 IL10 IL17A IL1A
10
Show member pathways
12.76 CCL5 CXCL8 IL1A IL2RA IL6
11
Show member pathways
12.63 IL1A IL1R1 IL6 PENK
12
Show member pathways
12.57 CXCL8 IL10 IL17A IL1A IL2RA IL5
13 12.51 CCL5 IL10 IL17A IL2RA
14
Show member pathways
12.44 IL10 IL17A IL1A IL1R1 IL2RA IL5
15
Show member pathways
12.41 IL1A IL1R1 IL2RA IL5
16
Show member pathways
12.4 IL10 IL17A IL1A IL5 IL6
17
Show member pathways
12.31 CXCL8 IL17A IL5 IL6
18
Show member pathways
12.24 IL10 IL17A IL1R1 IL6
19
Show member pathways
12.24 CXCL8 IL1A IL1R1 IL6
20
Show member pathways
12.19 CXCL8 IL1A IL1R1 IL6
21 12.15 CXCL8 IL10 IL1A IL6
22
Show member pathways
12.11 CXCL8 IL1R1 IL6
23 12.09 CXCL8 IL1A IL6
24 12.03 IL10 IL2RA IL5 IL6 IL7
25
Show member pathways
12.01 IL1A IL1R1 IL2RA IL5
26 12.01 CXCL8 IL10 IL17A IL1A IL6
27 11.99 CXCL8 IL1A IL1R1 IL6
28
Show member pathways
11.94 CCL5 CXCL8 CXCR3
29 11.92 IL1A IL1R1 IL2RA IL5 IL6 IL7
30 11.9 CXCL8 IL1A IL6
31 11.89 CXCL8 IL10 IL1R1 IL6
32 11.89 CCL5 CXCL8 IL17A IL1A IL6
33 11.87 CXCL8 IL1A IL6
34
Show member pathways
11.84 CXCL8 IL17A IL6
35 11.83 IL10 IL2RA IL6
36 11.8 CXCL8 IL1A IL6
37 11.78 CXCL8 IL5 IL6
38 11.77 CXCL8 IL10 IL1A IL6
39
Show member pathways
11.74 CXCL8 IL2RA IL5
40 11.68 CCL5 CXCL8 IL5 IL6
41
Show member pathways
11.65 CXCL8 IL1A IL6
42 11.6 CXCR3 IL10 IL17A IL1R1 IL2RA IL5
43 11.53 CXCL8 IL10 IL6
44 11.52 IL1A IL5 IL6
45 11.5 CXCL8 IL2RA IL6
46 11.49 IL10 IL2RA IL5
47 11.49 CCL5 CXCL8 IL10 IL1A IL1R1 IL6
48
Show member pathways
11.38 CCL5 CXCL8 IL10 IL17A IL1A IL1R1
49 11.35 IL10 IL1A IL6
50 11.35 IL17A IL5 IL6 IL7

GO Terms for Radiculopathy

Cellular components related to Radiculopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.56 CCL5 CXCL8 IL10 IL17A IL1A IL5
2 external side of plasma membrane GO:0009897 9.46 CXCR3 IL17A IL1R1 IL2RA
3 extracellular region GO:0005576 9.32 CCL5 CXCL8 IL10 IL17A IL1A IL1R1

Biological processes related to Radiculopathy according to GeneCards Suite gene sharing:

(show all 20)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.91 CCL5 CXCL8 IL10 IL17A IL1A IL5
2 negative regulation of cell proliferation GO:0008285 9.88 CXCL8 IL10 IL1A IL6
3 inflammatory response GO:0006954 9.81 CCL5 CXCL8 CXCR3 IL10 IL17A IL1A
4 chemotaxis GO:0006935 9.77 CCL5 CXCL8 CXCR3
5 cellular response to lipopolysaccharide GO:0071222 9.73 CXCL8 IL10 IL6
6 positive regulation of DNA binding transcription factor activity GO:0051091 9.71 IL10 IL5 IL6
7 immune response GO:0006955 9.65 CCL5 CXCL8 IL10 IL17A IL1A IL1R1
8 cellular response to interleukin-1 GO:0071347 9.63 CCL5 CXCL8 IL17A
9 chemokine-mediated signaling pathway GO:0070098 9.61 CCL5 CXCL8 CXCR3
10 positive regulation of leukocyte chemotaxis GO:0002690 9.58 CXCL8 IL6
11 positive regulation of T cell proliferation GO:0042102 9.58 CCL5 IL2RA IL6
12 positive regulation of chemokine production GO:0032722 9.57 IL6 IL7
13 positive regulation of T cell differentiation GO:0045582 9.55 IL2RA IL7
14 response to molecule of bacterial origin GO:0002237 9.52 CXCL8 IL10
15 negative regulation of G-protein coupled receptor protein signaling pathway GO:0045744 9.51 CCL5 CXCL8
16 positive regulation of JAK-STAT cascade GO:0046427 9.5 CCL5 IL5 IL6
17 positive regulation of immunoglobulin secretion GO:0051024 9.49 IL5 IL6
18 neutrophil activation GO:0042119 9.48 CCL5 CXCL8
19 positive regulation of neutrophil extravasation GO:2000391 9.37 IL1A IL1R1
20 cytokine-mediated signaling pathway GO:0019221 9.32 CCL5 CXCL8 IL10 IL17A IL1A IL1R1

Molecular functions related to Radiculopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.26 IL10 IL5 IL6 IL7
2 cytokine activity GO:0005125 9.23 CCL5 CXCL8 IL10 IL17A IL1A IL5

Sources for Radiculopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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