Aliases & Classifications for Radiculopathy

MalaCards integrated aliases for Radiculopathy:

Name: Radiculopathy 12 44 15 73
Nerve Root Disorder 12 73

Classifications:



External Ids:

Disease Ontology 12 DOID:4306
ICD10 33 M54.1 M54.10
MeSH 44 D011843
SNOMED-CT 68 72274001

Summaries for Radiculopathy

MalaCards based summary : Radiculopathy, also known as nerve root disorder, is related to meningitis and osteomyelitis, and has symptoms including neuralgia An important gene associated with Radiculopathy is IL6 (Interleukin 6), and among its related pathways/superpathways are Innate Immune System and ERK Signaling. The drugs Lidocaine and Betamethasone have been mentioned in the context of this disorder. Affiliated tissues include testes, spinal cord and dorsal root ganglion, and related phenotypes are hematopoietic system and immune system

Wikipedia : 76 Radiculopathy, also commonly referred to as pinched nerve, refers to a set of conditions in which one or... more...

Related Diseases for Radiculopathy

Diseases related to Radiculopathy via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 338)
# Related Disease Score Top Affiliating Genes
1 meningitis 29.7 CCL2 CXCL8 IL6
2 osteomyelitis 29.7 CXCL8 IL1A IL6
3 endometriosis 29.6 CCL2 CXCL8 IL6
4 arthritis 29.4 CCL2 CXCL8 IL17A IL1A IL6
5 temporal arteritis 29.4 CCL2 CCL5 IL6
6 rheumatoid arthritis 28.8 CCL2 CCL5 CXCL8 IL17A IL1A IL1R1
7 polyradiculopathy 11.1
8 pinched nerve 11.1
9 spinal stenosis 10.3
10 scorpion envenomation 10.2 CCL5 IL6
11 vaginitis 10.2 CXCL8 IL6
12 obesity-hypoventilation syndrome 10.2 CCL5 IL6
13 angioimmunoblastic lymphadenopathy with dysproteinemia 10.2 IL5 IL6
14 recurrent corneal erosion 10.2 CXCL8 IL6
15 acute transverse myelitis 10.2 CXCL8 IL6
16 pemphigoid gestationis 10.2 CCL11 IL5
17 streptococcal toxic-shock syndrome 10.2 CXCL8 IL6
18 leukoregulin 10.2 CXCL8 IL1A
19 viral pneumonia 10.2 IL17A IL6
20 acute generalized exanthematous pustulosis 10.2 CXCL8 IL17A
21 b-cell growth factor 10.2 IL6 IL7
22 chronic meningitis 10.2 CCL11 IL5
23 neurosyphilis 10.2 CXCL8 IL17A
24 respiratory syncytial virus infectious disease 10.2 CCL5 IL5
25 funisitis 10.2 CXCL8 IL6
26 spondylosis 10.2
27 neuropathy 10.2
28 angiostrongyliasis 10.2 CCL11 IL5
29 myelitis 10.2 CCL11 IL17A IL6
30 strongyloidiasis 10.2 CCL11 IL5
31 idiopathic neutropenia 10.2 CCL5 IL1A IL6
32 giant papillary conjunctivitis 10.2 CCL11 CXCL8
33 autoimmune disease of eyes, ear, nose and throat 10.2 CCL5 IL17A IL6
34 asymptomatic neurosyphilis 10.2 CXCL8 IL17A
35 central nervous system vasculitis 10.2 IL17A IL6
36 necatoriasis 10.1 CXCL8 IL5
37 multicentric castleman disease 10.1 IL5 IL6
38 eosinophilic gastroenteritis 10.1 CCL11 IL5
39 capillary leak syndrome 10.1 CXCL8 IL6
40 pulpitis 10.1 CXCL8 IL1A IL6
41 psoriatic arthritis 10.1 IL17A IL1A IL6
42 eosinophilic meningitis 10.1 CCL11 IL5
43 echinococcosis 10.1 IL17A IL5 IL6
44 bacterial vaginosis 10.1 CXCL8 IL1A IL6
45 cardiac sarcoidosis 10.1 CXCL8 IL5
46 dermatitis 10.1 CCL11 IL17A IL5
47 transverse myelitis 10.1 CXCL8 IL17A IL6
48 tonsillitis 10.1 CXCL8 IL1A IL6
49 aggressive periodontitis 10.1 CXCL8 IL1A IL6
50 cryopyrin-associated periodic syndrome 10.1 IL1R1 IL6

Graphical network of the top 20 diseases related to Radiculopathy:



Diseases related to Radiculopathy

Symptoms & Phenotypes for Radiculopathy

UMLS symptoms related to Radiculopathy:


neuralgia

MGI Mouse Phenotypes related to Radiculopathy:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.85 AVPR2 CCL11 CCL5 CXCR3 IL17A IL1A
2 immune system MP:0005387 9.65 CCL11 CCL2 CCL5 CXCR3 IL17A IL1A
3 respiratory system MP:0005388 9.1 CCL11 CXCR3 IL17A IL1R1 IL5 IL6

Drugs & Therapeutics for Radiculopathy

Drugs for Radiculopathy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 189)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Lidocaine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 137-58-6 3676
2
Betamethasone Approved, Vet_approved Phase 4,Phase 2,Not Applicable 378-44-9 9782
3
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 3,Not Applicable 148553-50-8 5486971
4
Acetaminophen Approved Phase 4,Phase 3,Not Applicable 103-90-2 1983
5
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable 1177-87-3
6
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 1,Not Applicable 50-02-2 5743
7
Meloxicam Approved, Vet_approved Phase 4,Not Applicable 71125-38-7 54677470 5281106
8
Milnacipran Approved, Investigational Phase 4 92623-85-3 65833
9
Triamcinolone Approved, Vet_approved Phase 4,Phase 3,Not Applicable 124-94-7 31307
10
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable 2180-92-9, 38396-39-3 2474
11
Oxycodone Approved, Illicit, Investigational Phase 4,Phase 3 76-42-6 5284603
12
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
13
Ibuprofen Approved Phase 4 15687-27-1 3672
14
Eplerenone Approved Phase 4 107724-20-9 443872 150310
15
Spironolactone Approved Phase 4 52-01-7, 1952-01-7 5833
16
Naproxen Approved, Vet_approved Phase 4 22204-53-1 1302 156391
17 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
19 Anti-Arrhythmia Agents Phase 4,Phase 1,Not Applicable
20 Betamethasone Valerate Phase 4,Phase 2,Not Applicable 2152-44-5
21 Anti-Asthmatic Agents Phase 4,Phase 2
22 Betamethasone benzoate Phase 4,Phase 2,Not Applicable
23 Betamethasone acetate Phase 4
24 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
25 Betamethasone sodium phosphate Phase 4,Phase 2,Not Applicable
26 Central Nervous System Depressants Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
27 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Not Applicable
28 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
29 Anesthetics, Local Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
30 Respiratory System Agents Phase 4,Phase 2
31 Hormones Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
32 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
33 Diuretics, Potassium Sparing Phase 4,Phase 1,Not Applicable
34 Anesthetics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
36 Betamethasone acetate phosphate Phase 4,Phase 2
37 Sodium Channel Blockers Phase 4,Phase 1,Not Applicable
38 Betamethasone-17,21-dipropionate Phase 4,Phase 2,Not Applicable
39 Bronchodilator Agents Phase 4
40 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
41 Analgesics Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
42 Calcium, Dietary Phase 4,Phase 3,Not Applicable
43 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Not Applicable
44 Antipyretics Phase 4,Not Applicable
45 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
46 BB 1101 Phase 4,Phase 2,Phase 1,Not Applicable
47 Antineoplastic Agents, Hormonal Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
48 Antiemetics Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
49 HIV Protease Inhibitors Phase 4,Phase 2,Phase 1,Not Applicable
50
protease inhibitors Phase 4,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 214)
# Name Status NCT ID Phase Drugs
1 A Post-marketing Evaluation of a Compound Traditional Chinese Herbal Medicine, Qishe Pill, on Cervical Radiculopathy Unknown status NCT01875562 Phase 4 Qishe Pill
2 Percutaneous HydroDiscectomy Compared to TESI for Radiculopathy Unknown status NCT02414698 Phase 4 TESI
3 Conservative Versus Aggressive Discectomy for Primary Disc Herniation With Radiculopathy Unknown status NCT01204008 Phase 4
4 Transforaminal Epidural Steroid Injection With Pulsed Radiofrequency for Chronic Lumbosacral Radicular Pain Management Unknown status NCT02930057 Phase 4 Celestone;Control
5 Comparison of the Efficacy of rTMS and tDCS of the Motor Cortex in Patients With Chronic Neuropathic Pain Completed NCT02030626 Phase 4
6 Arthroplasty Versus Fusion in Anterior Cervical Surgery: Prospective Study of the Impact on the Adjacent Level Completed NCT00554528 Phase 4
7 Caudal Epidural Steroid Injections for Low Back Pain/Sciatic Lumbar Pain Completed NCT01407913 Phase 4
8 Pregabalin and Radicular Pain Study (PARPS) Completed NCT01061697 Phase 4 Pregabalin
9 Milnacipran for Lumbosacral Radicular Pain Completed NCT01777581 Phase 4 Milnacipran;Placebo
10 High Frequency Stimulation Trials in Patients With Precision Spinal Cord Stimulator System Completed NCT02265848 Phase 4
11 Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™ Completed NCT01615328 Phase 4
12 C7-T1 Epidural Steroid Injections Versus Targeted Injection for Treatment of Cervical Radicular Pain Completed NCT02095197 Phase 4 Triamcinolone 80mg
13 Efficacy of Pregabalin in Patients With Radicular Pain Completed NCT00908375 Phase 4 Pregabalin;Sugar Pill
14 Pentoxifylline and Lumbar Radiculopathy Recruiting NCT03060434 Phase 4 Pentoxifylline Oral Tablet;Ibuprofen
15 Does Low-does Cervical Epidural Lidocaine Cause Transient Weakness? Recruiting NCT03382925 Phase 4 Lidocaine;Triamcinolone Acetonide;Normal saline
16 Comparative Trial Via Tranforaminal Approach Versus Epidural Catheter Via Interlaminar Approach Recruiting NCT03382821 Phase 4 Dexamethasone Sodium Phosphate 10 MG/ML;Lidocaine;Triamcinolone Acetonide 40mg/mL
17 Eplerenone as a Supplement to Epidural Steroid Injections Recruiting NCT03418649 Phase 4 Eplerenone 50 Mg Tab;Placebo Oral Tablet
18 Do Cervical Interlaminar Epidural Steroid Injections With Low-dose Lidocaine Cause Transient Objective Upper Extremity Weakness? A Prospective Randomized Controlled Trial Recruiting NCT03127137 Phase 4 Experimental Group 1 triamcinolone and lidocaine;Experimental Group 2 triamcinolone and saline
19 A Prospective Study to Compare Bupivacaine and Exparel Versus Bupivacaine or Exparel Alone for Postoperative Pain Relief Recruiting NCT03514277 Phase 4 Exparel;Bupivacaine
20 CT Guided Injection for Low Back Radiculopathy: A Randomized Clinical Trial Terminated NCT01267825 Phase 4 CT-guided corticosteroid+ bupivicaine;Standard medical care
21 Spinal Cord Stimulation for Chronic and Intractable Back Pain Terminated NCT00370695 Phase 4
22 Cervical Interlaminar Versus Transforaminal Epidural Steroid Injection Withdrawn NCT03165825 Phase 4 Transforaminal Epidural Steroid Injection with Dexamethasone;Interlaminar Epidural Steroid Injection with Betamethasone
23 Particulate vs. Nonparticulate Epidural Steroid Injections for Lumbar Foraminal Stenosis Withdrawn NCT03245671 Phase 4 Kenalog Injectable Product;Decadron Phosphate, Injectable
24 Pilot Study of Orphenadrine` in the Treatment of Muscle Cramps in Patients With Cirrhosis Unknown status NCT02423395 Phase 3 orphenadrine;Placebo
25 Safety and Efficacy of Neuromultivit in Treatment of Vertebrogenic Radiculopathy Completed NCT02508805 Phase 3 Neuromultivit;Voltaren;Sirdalud
26 Study to Evaluate the Efficacy and Safety of Lenalidomide in the Treatment of Painful Lumbar Radiculopathy Completed NCT00120120 Phase 2, Phase 3 Lenalidomide (CC-5013)
27 Trial of Efficacy and Safety of Pregabalin in Subjects With Neuropathic Pain Associated With Lumbo-Sacral Radiculopathy Completed NCT00159705 Phase 3 pregabalin
28 A 3-arm Multi-center, Randomized Controlled Study Comparing Transforaminal Corticosteroid, Transforaminal Etanercept and Transforaminal Saline for Lumbosacral Radiculopathy Completed NCT00733096 Phase 2, Phase 3 etanercept;methylprednisolone;normal saline
29 The Value of Traction in Treatment of Lumbar Radiculopathy Completed NCT00942227 Phase 3
30 The Value of Traction in the Treatment of Cervical Radiculopathy Completed NCT00979108 Phase 3
31 The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery Completed NCT01073995 Phase 3 Kenalog and Sensorcaine
32 Post-Approval Clinical Trial of the PCM® Cervical Disc Completed NCT01905930 Phase 3
33 Physiotherapy for Sciatica; Is Earlier Better? Completed NCT02618278 Phase 3
34 PCM Cervical Disc System Completed NCT00578812 Phase 3
35 Surgery Versus Standardized Non-operative Care for the Treatment of Lumbar Disc Herniations: A Canadian Trial Completed NCT01335646 Phase 3
36 Immediate Pain Relieving Effects of Sinbaro-3 for Low Back Pain Completed NCT02196129 Phase 3 Sinbaro-3;Hwangryun
37 Efficacy and Safety of Ralfinamide in Patients With Chronic Neuropathic Low Back Pain Completed NCT01019824 Phase 3 Ralfinamide
38 The Efficacy of Oral Steroids in the Treatment of Acute Sciatica Completed NCT00317447 Phase 3 Oral Prednisone
39 Neurosurgery Patient Outcomes in Treating Spinal Disorders Completed NCT01220921 Phase 3
40 Manual Physical Therapy and Exercise for Mechanical Neck Disorders Completed NCT00416117 Phase 2, Phase 3
41 NUCYNTA (Tapentadol Immediate Release) Versus Oxycodone Immediate Release in the Treatment of Acute Low Back Pain Completed NCT00986180 Phase 3 NUCYNTA;Oxycodone IR
42 Treatment of Pain Associated With Lumbosacral Radiculopathy in Adults Recruiting NCT03727100 Phase 3
43 Corticosteroid Lumbar Epidural Analgesia for Radiculopathy Recruiting NCT03372161 Phase 3 SP-102;Placebo
44 Clinical Research on the Efficacy of Bosinji on Herniated Intervertebral Disc of Lumbar Spine Recruiting NCT03386149 Phase 3 Bosinji;Loxonine tab.
45 Impact of Local Steroid Application in Extreme Lateral Lumbar Interbody Fusion Recruiting NCT03327272 Phase 3 Methylprednisolone;Saline
46 SI-6603 (Condoliase) Study for Lumbar Disc Herniation Recruiting NCT03607838 Phase 3 SI-6603;Sham injection
47 Twice Daily Oral ALLOD-2 vs. Placebo in the Treatment of Chronic Low Back Pain (ANODYNE-4) Active, not recruiting NCT03201393 Phase 2, Phase 3 ALLOD-2 Capsules;Placebo Capsules
48 Lumbar Transforaminal Epidural Corticosteroid Injection(s) Versus Defined Physical Therapy Terminated NCT01443819 Phase 3
49 INFUSE®Bone Graft in Transforaminal Lumbar Interbody Fusion for Degenerative Disease of Lumbosacral Spine Terminated NCT01415908 Phase 3
50 Qishe Pill for Cervical Radiculopathy Unknown status NCT01274936 Phase 2 Qishe Pill;Qishe Placebo

Search NIH Clinical Center for Radiculopathy

Cochrane evidence based reviews: radiculopathy

Genetic Tests for Radiculopathy

Anatomical Context for Radiculopathy

MalaCards organs/tissues related to Radiculopathy:

41
Testes, Spinal Cord, Dorsal Root Ganglion, Bone, Brain, Myeloid, Cortex

Publications for Radiculopathy

Articles related to Radiculopathy:

(show top 50) (show all 1048)
# Title Authors Year
1
The efficacy of cauda epidural steroid injections with targeted indwelling catheter and manipulation in managing patients with lumbar disc herniation with radiculopathy: a prospective, randomized, single-blind controlled trial. ( 29410375 )
2018
2
The Effect of Pregabalin and Metformin on Subacute and Chronic Radiculopathy. ( 29531924 )
2018
3
A novel noninstrumented surgical approach for foramen reconstruction for isthmic spondylolisthesis in patients with radiculopathy: preliminary clinical and radiographic outcomes. ( 29290136 )
2018
4
Calf muscle hypertrophy following S1 radiculopathy: A stress disorder caused by hyperactivity with variable response to treatmen. ( 29451471 )
2018
5
The effectiveness of therapeutic strategies for patients with radiculopathy: A network meta-analysis. ( 29651898 )
2018
6
An awake, minimally-invasive, fully-endoscopic surgical technique for treating lumbar radiculopathy secondary to heterotopic foraminal bone formation after a minimally invasive transforaminal lumbar interbody fusion with BMP: technical note. ( 29732437 )
2018
7
Return to work following surgery for lumbar radiculopathy: a systematic review. ( 29800705 )
2018
8
Comparison between cervical disc arthroplasty and conservative treatment for patients with single level cervical radiculopathy at C5/6. ( 29409935 )
2018
9
Sensitivity and Specificity of Modified Bragard Test in Patients With Lumbosacral Radiculopathy Using Electrodiagnosis as a Reference Standard. ( 29628807 )
2018
10
The impact of mental health on patient-reported outcomes in cervical radiculopathy or myelopathy surgery. ( 29907392 )
2018
11
Salvage of cervical motor radiculopathy using peripheral nerve transfer reconstruction. ( 29745256 )
2018
12
Correction to: Minimally invasive posterior cervical foraminotomy for treatment of radiculopathy : An effective, time-tested, and cost-efficient motion-preservation technique. ( 29270676 )
2018
13
A case report: C2 radiculopathy induced by neck flexion due to the cord compression of C2 segmental type vertebral artery relieved by microvascular decompression. ( 29900031 )
2018
14
Extra-Osseous Ewing Sarcoma of Sciatic Nerve Masquerading as Benign Nerve Sheath Tumor and Presented as Lumbar Radiculopathy: Case Report and Review of Literature. ( 29673820 )
2018
15
Investigation of the effectiveness of therapeutic ultrasound with high-resolution ultrasonographic cross-sectional area measurement of cervical nerve roots in patients with chronic cervical radiculopathy: a prospective, controlled, single-blind study. ( 29318418 )
2018
16
Sacral Myeloid Sarcoma Manifesting as Radiculopathy in a Pediatric Patient: An Unusual Form of Myeloid Leukemia Relapse. ( 29888021 )
2018
17
Posterior percutaneous full-endoscopic cervical discectomy under local anesthesia for cervical radiculopathy due to soft-disc herniation: a preliminary clinical study. ( 29957146 )
2018
18
Non-Small Cell Lung Cancer Drop Metastasis Causing Lumbosacral Radiculopathy. ( 29878259 )
2018
19
Cervical radiculopathy and cervical myelopathy: diagnosis and management in primary care. ( 29284641 )
2018
20
Cervical Radiculopathy: Effectiveness of Adding Traction to Physical Therapy. A Systematic Review and Meta-Analysis of Randomized Controlled Trials. ( 29315428 )
2018
21
Energy Impairments in Older Adults With Low Back Pain and Radiculopathy: A Matched Case-Control Study. ( 29698638 )
2018
22
Minimally Invasive Transtubular Endoscopic Decompression for L5 Radiculopathy Induced by Lumbosacral Extraforaminal Lesions. ( 29713405 )
2018
23
Complications of Full-Endoscopic Versus Microendoscopic Foraminotomy for Cervical Radiculopathy: A Systematic Review and Meta-Analysis. ( 29602008 )
2018
24
N-Palmitoyl Ethanol Amide Pharmacological Treatment in Patients With Nonsurgical Lumbar Radiculopathy. ( 29364513 )
2018
25
Painless motor radiculopathy of the cervical spine: clinical and radiological characteristics and long-term outcomes after operative decompression. ( 29570047 )
2018
26
Contralateral radiculopathy after transforaminal lumbar interbody fusion in the treatment of lumbar degenerative diseases: A Case Series. ( 29668622 )
2018
27
Comparison of Anterior Cervical Discectomy and Fusion to Posterior Cervical Foraminotomy for Cervical Radiculopathy: Utilization, Costs and Adverse Events 2003 to 2014. ( 29548034 )
2018
28
Factors related to subjective satisfaction following microendoscopic foraminotomy for cervical radiculopathy. ( 29361919 )
2018
29
Apparent C8-T1 radiculopathy with hand weakness due to mid-cervical spondylosis. ( 29097135 )
2018
30
Sacral Stress Fracture Complicated by L5 Radiculopathy in a Patient with Rheumatoid Arthritis. ( 30369612 )
2018
31
Artificial disc replacement versus fusion in patients with cervical degenerative disc disease with radiculopathy: 5-year outcomes from the National Swedish Spine Register. ( 30485205 )
2018
32
Tophaceous Gout in the Lumbar Spine Causing Radiculopathy. ( 30297196 )
2018
33
Chronic Unilateral Temporo-Occipital Headache Attributed to Unilateral C3 Radiculopathy. ( 30459902 )
2018
34
Sudden-onset C8 Radiculopathy due to a Plexiform Schwannoma of the Cervical Nerve Root. ( 29984772 )
2018
35
Surgical Treatment of Cervical Radiculopathy: Meta-analysis of Randomized Controlled Trials. ( 28700452 )
2018
36
Suppression of Sympathetic Nerve Sprouting by Local Administration of an α-antagonist Around the Dorsal Root Ganglion in a Lumbar Radiculopathy Model. ( 28723879 )
2018
37
NuNec™ Cervical Disc Arthroplasty Improves Quality of Life in Cervical Radiculopathy and Myelopathy: A 2-yr Follow-up. ( 28973309 )
2018
38
Diagnostic Value of Magnetic Resonance Neurography in Cervical Radiculopathy: Plexus Patterns and Peripheral Nerve Lesions. ( 28976477 )
2018
39
Extraforaminal Discal Cyst as Cause of Radiculopathy. ( 28987844 )
2018
40
Structured postoperative physiotherapy in patients with cervical radiculopathy: 6-month outcomes of a randomized clinical trial. ( 29087809 )
2018
41
Anterior Cervical Decompression and Fusion or Posterior Foraminotomy for Cervical Radiculopathy: Results of a Single-Center Series. ( 29132169 )
2018
42
A Novel Technique for Cervical Facet Joint Hyperplasia-Spondylotic Radiculopathy by Laminar and Lateral Mass Screw Cofixations. ( 29146433 )
2018
43
Investigations for radiculopathy: The patient perspective. A qualitative, interpretative inquiry. ( 29182989 )
2018
44
Rarely Encountered, Seldom Considered: Posterior Tibial Nerve Schwannoma Mimicking Lumbar Radiculopathy. ( 29456371 )
2018
45
ISSLS PRIZE IN BASIC SCIENCE 2018: Growth differentiation factor-6 attenuated pro-inflammatory molecular changes in the rabbit anular-puncture model and degenerated disc-induced pain generation in the rat xenograft radiculopathy model. ( 29460012 )
2018
46
Contralateral Radiculopathy: A Kernohan-Woltman Notch-like Phenomenon. ( 29492153 )
2018
47
Application of algometry in patients with cervical and lumbar radiculopathy. ( 29526842 )
2018
48
Treatment of cervical radiculopathy: A review of the evolution and economics. ( 29527393 )
2018
49
Effects of preoperative mental distress versus surgical modality, arthroplasty, or fusion on long-term outcome in patients with cervical radiculopathy. ( 30004317 )
2018
50
Is the symptom of cervical or lumbar radiculopathy an evidence of spinal instability? ( 30008523 )
2018

Variations for Radiculopathy

Expression for Radiculopathy

Search GEO for disease gene expression data for Radiculopathy.

Pathways for Radiculopathy

Pathways related to Radiculopathy according to GeneCards Suite gene sharing:

(show top 50) (show all 59)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.94 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
2
Show member pathways
13.76 CCL11 CCL2 CCL5 CXCL8 CXCR3 IL17A
3
Show member pathways
13.6 CCL11 CCL2 CCL5 CXCL8 CXCR3 IL17A
4
Show member pathways
13.43 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
5
Show member pathways
13.3 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
6
Show member pathways
13.25 CCL11 CCL2 CCL5 CXCL8 CXCR3 IL17A
7
Show member pathways
13 CCL11 CCL2 CCL5 CXCL8 CXCR3 IL17A
8
Show member pathways
12.98 CCL2 CCL5 CXCL8 IL1R1 IL6
9
Show member pathways
12.84 CCL11 CXCL8 IL17A IL1A IL5 IL6
10
Show member pathways
12.83 CCL11 CCL2 CCL5 CXCL8 CXCR3
11
Show member pathways
12.75 CCL2 CCL5 CXCL8 IL1A IL6
12
Show member pathways
12.64 IL1A IL1R1 IL6 PENK
13
Show member pathways
12.56 IL17A IL1A IL1R1 IL5 IL6
14
Show member pathways
12.39 IL17A IL1A IL5 IL6
15
Show member pathways
12.37 CCL11 CCL2 CXCL8 IL17A IL5 IL6
16
Show member pathways
12.3 CXCL8 IL17A IL1A IL5 IL6 PENK
17
Show member pathways
12.27 CXCL8 IL1A IL1R1 IL6
18
Show member pathways
12.25 CCL11 CCL2 CCL5 CXCL8 CXCR3 IL1A
19
Show member pathways
12.2 CXCL8 IL1A IL1R1 IL6
20
Show member pathways
12.16 CCL11 CXCL8 IL1R1 IL6
21 12.11 CXCL8 IL1A IL6
22 12.1 CXCL8 IL1A IL6
23 12.08 CCL2 CXCL8 IL1A IL1R1 IL6
24
Show member pathways
12.05 CCL11 CCL2 CCL5 CXCL8 CXCR3
25 12.03 CCL2 IL1A IL1R1
26 12.01 CCL11 CCL2 CXCL8 IL17A IL1A IL6
27
Show member pathways
12 IL17A IL1R1 IL6
28
Show member pathways
11.97 IL1A IL1R1 IL5
29 11.95 IL1A IL1R1 IL5 IL6 IL7
30 11.94 IL5 IL6 IL7
31 11.92 CCL2 CCL5 IL6
32 11.91 CCL2 CXCL8 IL1A IL6
33 11.9 CXCL8 IL1A IL6
34 11.86 CCL2 CCL5 CXCL8 IL17A IL1A IL6
35 11.85 CXCL8 IL1R1 IL6
36 11.85 CXCR3 IL17A IL1R1 IL5 IL7
37
Show member pathways
11.83 CXCL8 IL17A IL6
38 11.8 CXCL8 IL1A IL6
39 11.79 CCL11 CCL2 CCL5 IL17A IL6
40 11.77 CXCL8 IL5 IL6
41 11.74 CXCL8 IL1A IL6
42
Show member pathways
11.71 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
43 11.68 CCL11 CCL2 CCL5 CXCL8 IL5 IL6
44
Show member pathways
11.64 CXCL8 IL1A IL6
45 11.54 CCL2 CCL5 CXCL8 IL1A IL1R1 IL6
46 11.53 CCL2 CXCL8 IL6
47 11.52 IL1A IL5 IL6
48 11.5 CCL11 CXCL8 IL6
49 11.39 IL17A IL5 IL6 IL7
50 11.36 CCL5 IL1A IL6

GO Terms for Radiculopathy

Cellular components related to Radiculopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.61 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
2 extracellular region GO:0005576 9.36 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A

Biological processes related to Radiculopathy according to GeneCards Suite gene sharing:

(show all 27)
# Name GO ID Score Top Affiliating Genes
1 regulation of signaling receptor activity GO:0010469 9.96 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
2 inflammatory response GO:0006954 9.85 CCL11 CCL2 CCL5 CXCL8 CXCR3 IL17A
3 chemotaxis GO:0006935 9.83 CCL11 CCL2 CCL5 CXCL8 CXCR3
4 cellular response to lipopolysaccharide GO:0071222 9.81 CCL2 CXCL8 IL6
5 cellular response to tumor necrosis factor GO:0071356 9.81 CCL11 CCL2 CCL5 CXCL8
6 positive regulation of angiogenesis GO:0045766 9.8 CCL11 CXCL8 IL1A
7 cellular response to interferon-gamma GO:0071346 9.77 CCL11 CCL2 CCL5
8 cellular response to interleukin-1 GO:0071347 9.77 CCL11 CCL2 CCL5 CXCL8 IL17A
9 neutrophil chemotaxis GO:0030593 9.76 CCL11 CCL2 CCL5 CXCL8
10 cell chemotaxis GO:0060326 9.74 CCL2 CCL5 CXCR3
11 humoral immune response GO:0006959 9.73 CCL2 IL6 IL7
12 lymphocyte chemotaxis GO:0048247 9.72 CCL11 CCL2 CCL5
13 chemokine-mediated signaling pathway GO:0070098 9.72 CCL11 CCL2 CCL5 CXCL8 CXCR3
14 monocyte chemotaxis GO:0002548 9.71 CCL11 CCL2 CCL5 IL6
15 cellular response to fibroblast growth factor stimulus GO:0044344 9.7 CCL2 CCL5 CXCL8
16 immune response GO:0006955 9.7 CCL11 CCL2 CCL5 CXCL8 CXCR3 IL17A
17 positive regulation of JAK-STAT cascade GO:0046427 9.67 CCL5 IL5 IL6
18 eosinophil chemotaxis GO:0048245 9.65 CCL11 CCL2 CCL5
19 positive regulation of chemokine production GO:0032722 9.62 IL6 IL7
20 macrophage chemotaxis GO:0048246 9.62 CCL2 CCL5
21 negative regulation of G protein-coupled receptor signaling pathway GO:0045744 9.61 CCL5 CXCL8
22 PERK-mediated unfolded protein response GO:0036499 9.61 CCL2 CXCL8
23 positive regulation of immunoglobulin secretion GO:0051024 9.6 IL5 IL6
24 neutrophil activation GO:0042119 9.58 CCL5 CXCL8
25 cytokine-mediated signaling pathway GO:0019221 9.32 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
26 signal transduction GO:0007165 10.12 AVPR2 CCL11 CCL2 CXCL8 CXCR3 IL1R1
27 G protein-coupled receptor signaling pathway GO:0007186 10.08 AVPR2 CCL11 CCL2 CCL5 CXCL8 CXCR3

Molecular functions related to Radiculopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 growth factor activity GO:0008083 9.43 IL5 IL6 IL7
2 CCR chemokine receptor binding GO:0048020 9.33 CCL11 CCL2 CCL5
3 cytokine activity GO:0005125 9.28 CCL11 CCL2 CCL5 CXCL8 IL17A IL1A
4 chemokine activity GO:0008009 9.26 CCL11 CCL2 CCL5 CXCL8

Sources for Radiculopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
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37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
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55 Novoseek
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62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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