RD
MCID: RDN004
MIFTS: 15

Radin Blood Group Antigen (RD)

Categories: Genetic diseases, Blood diseases

Aliases & Classifications for Radin Blood Group Antigen

MalaCards integrated aliases for Radin Blood Group Antigen:

Name: Radin Blood Group Antigen 57
Blood Group--Radin Antigen 57
Rd 57

Classifications:



External Ids:

OMIM 57 111620
MedGen 42 C1862204

Summaries for Radin Blood Group Antigen

OMIM : 57 Radin is a rare red cell antigen discovered by Rausen et al. (1967) in 5 families with varying ethnic backgrounds. It has been shown to cause mild to moderate hemolytic disease of the newborn in some cases. The Radin antigen is determined by a polymorphism in the ERMAP gene (609017.0003) and thus is a member of the blood group Scianna (Wagner et al., 2003). Radin has alternatively been labeled Sc4 to reflect this relationship. Harvey et al. (1983) estimated the frequency of the Radin antigen among Europeans to be 0.04% to 0.66% with the highest frequencies occurring among Swedes and Danes. (111620)

MalaCards based summary : Radin Blood Group Antigen, also known as blood group--radin antigen, is related to respiratory distress syndrome in premature infants and restrictive dermopathy, lethal. An important gene associated with Radin Blood Group Antigen is ERMAP (Erythroblast Membrane Associated Protein (Scianna Blood Group)). Related phenotype is abnormal immunoglobulin level.

Related Diseases for Radin Blood Group Antigen

Diseases related to Radin Blood Group Antigen via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 respiratory distress syndrome in premature infants 11.8
2 restrictive dermopathy, lethal 11.6
3 reticular dysgenesis 11.6
4 respiratory distress syndrome, infant 11.0
5 renal hypodysplasia/aplasia 1 10.9
6 renal hypodysplasia/aplasia 2 10.9
7 bronchopulmonary dysplasia 10.9
8 refsum disease, classic 10.9
9 adult respiratory distress syndrome 10.9
10 retinitis 10.5
11 retinitis pigmentosa 10.3
12 leber congenital amaurosis 4 10.3
13 rhabdomyosarcoma 10.3
14 retinal degeneration 10.3
15 choroiditis 10.1
16 cone-rod dystrophy 2 10.0
17 embryonal rhabdomyosarcoma 9.9
18 fundus dystrophy 9.9
19 butterfly-shaped pigment dystrophy 9.9
20 macular degeneration, age-related, 1 9.8
21 retinal disease 9.8
22 influenza 9.8
23 haemophilus influenzae 9.8
24 breast cancer 9.7
25 hepatocellular carcinoma 9.7
26 macular dystrophy, concentric annular 9.7
27 acheiropody 9.7
28 polycystic kidney disease 4 with or without polycystic liver disease 9.7
29 enhanced s-cone syndrome 9.7
30 squamous cell carcinoma, head and neck 9.7
31 rett syndrome 9.7
32 aging 9.7
33 cervical cancer 9.7
34 body mass index quantitative trait locus 1 9.7
35 hepatitis c virus 9.7
36 hepatitis 9.7
37 thrombocytopenia 9.7
38 vitelliform macular dystrophy 9.7
39 cone dystrophy 9.7
40 acrofacial dysostosis 9.7
41 interstitial emphysema 9.7
42 hydronephrosis 9.7
43 ecthyma 9.7
44 geographic tongue 9.7
45 rheumatic disease 9.7
46 squamous cell carcinoma 9.7
47 hepatitis c 9.7
48 dysostosis 9.7
49 enthesopathy 9.7
50 cervicitis 9.7

Graphical network of the top 20 diseases related to Radin Blood Group Antigen:



Diseases related to Radin Blood Group Antigen

Symptoms & Phenotypes for Radin Blood Group Antigen

Clinical features from OMIM:

111620

Human phenotypes related to Radin Blood Group Antigen:

32
# Description HPO Frequency HPO Source Accession
1 abnormal immunoglobulin level 32 HP:0010701

Drugs & Therapeutics for Radin Blood Group Antigen

Search Clinical Trials , NIH Clinical Center for Radin Blood Group Antigen

Genetic Tests for Radin Blood Group Antigen

Anatomical Context for Radin Blood Group Antigen

Publications for Radin Blood Group Antigen

Variations for Radin Blood Group Antigen

Expression for Radin Blood Group Antigen

Search GEO for disease gene expression data for Radin Blood Group Antigen.

Pathways for Radin Blood Group Antigen

GO Terms for Radin Blood Group Antigen

Sources for Radin Blood Group Antigen

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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