Rare Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: RRT020 MIFTS: 43	Rare Tumor Categories: Cancer diseases, Eye diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Rare Tumor

MalaCards integrated aliases for Rare Tumor:

Name: Rare Tumor ⁵⁹

Rare Neoplasm ⁵⁹

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Eye diseases

See all MalaCards categories (disease lists)

External Ids:

UMLS via Orphanet ⁷³ C0375111

Orphanet ⁵⁹ ORPHA98057

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Summaries for Rare Tumor

MalaCards based summary : Rare Tumor, also known as rare neoplasm, is related to desmoplastic small round cell tumor and dermatofibrosarcoma protuberans. An important gene associated with Rare Tumor is EWSR1 (EWS RNA Binding Protein 1), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Cytoskeletal Signaling. The drugs leucovorin and Pemetrexed have been mentioned in the context of this disorder. Affiliated tissues include breast, pancreas and liver, and related phenotypes are homeostasis/metabolism and immune system

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Related Diseases for Rare Tumor

Diseases in the Rare Tumor family:

Rare Eye Tumor

Diseases related to Rare Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 661)

#	Related Disease	Score	Top Affiliating Genes
1	desmoplastic small round cell tumor	32.0	EWSR1 DES
2	dermatofibrosarcoma protuberans	31.9	KIT DES ACTC1
3	rhabdomyosarcoma	30.5	EWSR1 DES ACTC1
4	mesenchymal cell neoplasm	30.5	KIT EWSR1
5	leiomyosarcoma	30.5	KIT DES ACTC1
6	fibrous histiocytoma	30.3	EWSR1 DES ACTC1
7	ewing's family of tumors	30.3	KIT EWSR1
8	leiomyoma	30.3	KIT DES ACTC1
9	syringocystadenoma papilliferum	30.2	DES ACTC1
10	spindle cell lipoma	30.2	DES ACTC1
11	congenital fibrosarcoma	30.1	DES ACTC1
12	glomus tumor	30.1	DES ACTC1
13	carcinosarcoma	30.1	KIT DES ACTC1
14	spindle cell sarcoma	30.1	NF2 DES ACTC1
15	gastrointestinal stromal tumor	30.1	KIT DES ACTC1
16	biphasic synovial sarcoma	30.0	EWSR1 DES
17	angiolipoma	30.0	DES ACTC1
18	parachordoma	30.0	DES ACTC1
19	glomangioma	30.0	DES ACTC1
20	ossifying fibromyxoid tumor	30.0	DES ACTC1
21	malignant fibroxanthoma	30.0	DES ACTC1
22	angiomyolipoma	29.9	KIT DES ACTC1
23	hemangiopericytoma, malignant	29.9	DES ACTC1
24	adenosarcoma	29.9	KIT DES
25	fibromatosis	29.9	KIT DES ACTC1
26	follicular dendritic cell sarcoma	29.8	KIT FCER2 CR2
27	spindle cell liposarcoma	29.7	KIT CR2
28	malignant mesenchymoma	29.7	KIT EWSR1 DES
29	constipation	29.7	SST RET KIT
30	neurilemmoma	29.6	NF2 KIT DES
31	perivascular epithelioid cell tumor	29.6	KIT DES ACTC1
32	inflammatory myofibroblastic tumor	29.6	KIT DES CR2 ACTC1
33	embryonal sarcoma	29.5	KIT DES
34	muscle cancer	29.5	KIT EWSR1 DES
35	reticulum cell sarcoma	29.5	FCER2 DES CR2 ACTC1
36	endocrine gland cancer	29.5	SST RET MMP2
37	neurofibromatosis, type iv, of riccardi	29.4	RET NF2 KIT
38	chondromyxoid fibroma	29.2	DES ACTC1
39	smooth muscle tumor	29.2	KIT DES CR2 ACTC1
40	ewing sarcoma	29.0	MMP2 KIT EWSR1 DES
41	malignant peripheral nerve sheath tumor	28.9	NF2 KIT ACTC1
42	dendritic cell tumor	28.8	FSCN1 FCER2 CR2 ACTC1
43	rare tumor of pancreas	12.2
44	rare tumor of gallbladder and extrahepatic biliary tract	12.1
45	rare tumor of small intestine	12.1
46	rare tumor of intestine	12.1
47	non-rare tumor	12.1
48	rare tumor of neuroepithelial tissue	12.1
49	rare tumor of salivary glands	12.1
50	hepatocellular carcinoma	11.6

Graphical network of the top 20 diseases related to Rare Tumor:

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Symptoms & Phenotypes for Rare Tumor

MGI Mouse Phenotypes related to Rare Tumor:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.96	ACTC1 CR2 DES FCER2 KIT LATS2
2	immune system	MP:0005387	9.76	CR2 FCER2 FSCN1 KIT MMP2 NF2
3	mortality/aging	MP:0010768	9.7	ACTC1 CR2 DES FCER2 FSCN1 KIT
4	muscle	MP:0005369	9.1	ACTC1 DES KIT LATS2 MMP2 RET

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Drugs & Therapeutics for Rare Tumor

Drugs for Rare Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 125)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

leucovorin

Approved

Phase 2, Phase 3

58-05-9

143 6006

Pemetrexed

Approved, Investigational

Phase 2, Phase 3

150399-23-8, 137281-23-3

60843 446556

Methylcobalamin

Approved, Experimental, Investigational

Phase 2, Phase 3

13422-55-4

Hydroxocobalamin

Approved

Phase 2, Phase 3

13422-51-0

11953898 15589840

Bevacizumab

Approved, Investigational

Phase 2, Phase 3

216974-75-3

Folic acid

Approved, Nutraceutical, Vet_approved

Phase 2, Phase 3

59-30-3

6037

Cyanocobalamin

Approved, Nutraceutical

Phase 2, Phase 3

68-19-9

44176380

Cobalamin

Experimental

Phase 2, Phase 3

13408-78-1

6857388

Folic Acid Antagonists

Phase 2, Phase 3

Vitamin B9

Phase 2, Phase 3

Folate

Phase 2, Phase 3

Nucleic Acid Synthesis Inhibitors

Phase 2, Phase 3

Vitamin B Complex

Phase 2, Phase 3

Vitamins

Phase 2, Phase 3

Vitamin B 12

Phase 2, Phase 3

Vitamin B12

Phase 2, Phase 3

Vincristine

Approved, Investigational

Phase 2

57-22-7, 2068-78-2

5978

Doxorubicin

Approved, Investigational

Phase 2

23214-92-8

31703

Mitotane

Approved

Phase 2

53-19-0

4211

Etoposide

Approved

Phase 2

33419-42-0

36462

Trastuzumab

Approved, Investigational

Phase 2

180288-69-1

9903

Olaparib

Approved

Phase 2

763113-22-0

23725625

Gefitinib

Approved, Investigational

Phase 2

184475-35-2

123631

Sirolimus

Approved, Investigational

Phase 2

53123-88-9

6436030 5284616 46835353

Palbociclib

Approved, Investigational

Phase 2

571190-30-2

5330286 11431660 5005498

afatinib

Approved

Phase 2

439081-18-2, 850140-72-6

10184653

Vemurafenib

Approved

Phase 2

918504-65-1

42611257 23252090

Miconazole

Approved, Investigational, Vet_approved

Phase 2

22916-47-8

4189

Dabrafenib

Approved, Investigational

Phase 2

1195765-45-7

44462760 44516822

Everolimus

Approved

Phase 2

159351-69-6

6442177 70789204

Cisplatin

Approved

Phase 2

15663-27-1

84093 441203 2767

Durvalumab

Approved, Investigational

Phase 2

1428935-60-7

Ifosfamide

Approved

Phase 2

3778-73-2

3690

Paclitaxel

Approved, Vet_approved

Phase 2

33069-62-4

36314

Tamoxifen

Approved

Phase 2

10540-29-1

2733526

Progesterone

Approved, Vet_approved

Phase 2

57-83-0

5994

rituximab

Approved

Phase 2

174722-31-7

10201696

Gemcitabine

Approved

Phase 2

95058-81-4

60750

Oxaliplatin

Approved, Investigational

Phase 2

61825-94-3

5310940 9887054 43805 6857599

Dopamine

Approved

Phase 2

51-61-6, 62-31-7

681

Salmon Calcitonin

Approved, Investigational

Phase 2

47931-85-1

16129616

Levodopa

Approved

Phase 2

59-92-7

6047

Imiquimod

Approved, Investigational

Phase 1, Phase 2

99011-02-6

57469

Tremelimumab

Investigational

Phase 2

745013-59-6

Calcitonin gene-related peptide

Investigational

Phase 2

83652-28-2

Antineoplastic Agents, Phytogenic

Phase 2

Tubulin Modulators

Phase 2

Antimitotic Agents

Phase 2

Liposomal doxorubicin

Phase 2

31703

Topoisomerase Inhibitors

Phase 2

Interventional clinical trials:

(show all 41)

#	Name	Status	NCT ID	Phase	Drugs
1	A Phase II-III Randomized Trial Pemetrexed-Cisplatin Chemotherapy With or Without Bevacizumab (Avastin), 15 mg/kg, for Malignant Pleural Mesothelioma (MPM)	Completed	NCT00651456	Phase 2, Phase 3	Standard Chemotherapy (Pemetrexed and Cisplatin);Standard Chemotherapy (Pemetrexed and Cisplatin) + Bevacizumab
2	Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy (HIPEC) for Adrenocortical Carcinoma	Completed	NCT01833832	Phase 2	Cisplatin;sodium thiosulfate
3	A Study of Combination Chemotherapy & Surgical Resection in the Tx of Adrenocortical Cancer: Mitotane & Continuous Infusion Doxorubicin, Vincristine & Etoposide w/the P-glycoprotein Antagonist, Tariquidar (XR9576), Before & After Surgical Resection	Completed	NCT00071058	Phase 2	XR9576 (Tariquidar)
4	Efficacy and Safety of Targeted Precision Therapy in Refractory Tumor With Druggable Molecular Event	Recruiting	NCT03239015	Phase 2	Gefitinib;Erlotinib;Afatinib;Trastuzumab;Oxazolidine;Olaparib;Everolimus;Cabozantinib;Vemurafenib;Dabrafenib;Palbociclib
5	Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy (HIPEC) for Adrenocortical Carcinoma	Recruiting	NCT03127774	Phase 2	Cisplatin;Sodium thiosulfate
6	A Phase II Study of Durvalumab (MEDI4736) (Anti-PD-L1 Antibody) in Combination With Tremelimumab (Anti-CTLA-4 Antibody) in Subjects With Advanced Rare Solid Tumors	Recruiting	NCT02938793	Phase 2	Durvalumab;Tremelimumab
7	Prospective Phase II Study Evaluating a Multimodal Care of Inguinal Node Metastasis in Squamous Cell Carcinoma of the Penis by Bilateral Lymphadenectomy and Chemotherapy TIP	Recruiting	NCT02817958	Phase 2	Chemotherapy TIP
8	Phase II Study of Hormone Therapy With Tamoxifen in Patients With Well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression	Recruiting	NCT03870399	Phase 2	Tamoxifen
9	Bendamustine and Rituximab for the Treatment of Splenic Marginal Zone Lymphoma. The International Extranodal Lymphoma Study Group (IELSG) 36 Phase II Prospective Study	Active, not recruiting	NCT02853370	Phase 2	Bendamustine and Rituximab
10	A Single-center, Open Label Study for Evaluation of the Safety and Efficacy of Oshadi D and Oshadi R for Malignant Mesothelioma Treatment - A Phase IIa Study	Suspended	NCT01627795	Phase 1, Phase 2	Oshadi D and Oshadi R
11	Open Labeled Phase II Study Evaluating Efficacy and Safety of Chemotherapy With Gemcitabine - Oxaliplatin Combination for Advanced Refractory Thyroid Cancer Patients	Terminated	NCT02472080	Phase 2	gemcitabine -oxaliplatine combination
12	Efficacy and Tolerance of RADIOEMBOLIZATION for Patients With Unresectable Intrahepatic Cholangiocarcinoma With Tumor Progression After First-line Therapy	Terminated	NCT01383746	Phase 1, Phase 2
13	Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer.	Terminated	NCT00647140	Phase 2
14	Phase I/II Study of Peptide Vaccination Associated With Tumoral Immunomodulation With Proinflammatory Cytokines and Imiquimod in Patients With Advanced Metastatic Melanoma	Terminated	NCT01191034	Phase 1, Phase 2	Vaccine MAGE-3.A1 peptide, or the NA17.A2 peptide + IL-2, IFN-α and GMCSF, Imiquimod.
15	Phase I/II Study of Peptide Vaccination Associated With GM-CT-01, a Galactomannan Oligomer That Inhibits Galectin-3, in Patients With Advanced Metastatic Melanoma	Terminated	NCT01723813	Phase 1, Phase 2
16	Phase I/II Study of Xeloda and Gleevec in Patients With Advanced Solid Tumors	Completed	NCT00183833	Phase 1	capecitabine, imatinib mesylate
17	Imatinib Mesylate And Cyclophosphamide In Metronomic Administration: Dose Escalation Study Of Imatinib Mesylate in Patient With Rare Tumor (Phase I Study)	Completed	NCT01046487	Phase 1	Imatinib mesylate, Cyclophosphamide (Dosing level 1 );Imatinib mesylate, Cyclophosphamide (Dosing level 2);Imatinib mesylate, Cyclophosphamide (Dosing level 3)
18	A Phase I Dose Escalation Study of Autologous Expanded Natural Killer (NK) Cells for Immunotherapy of Relapsed Refractory Neuroblastoma With Dinutuximab +/- Lenalidomide	Recruiting	NCT02573896	Phase 1	Ch14.18;Lenalidomide
19	A Phase I/II Trial of IL-13-PE in Patients With Treatment Refractory Malignancies With a Focus on Metastatic and Locally Advanced Adrenocortical Carcinoma	Terminated	NCT01832974	Phase 1	IL-13-PE
20	Contribution of F18-FDG PET/CT to the Early Assessment of Pazopanib Therapy Efficacy in Advanced Soft Tissue Sarcoma	Unknown status	NCT01594203
21	Evaluation of New Biomarkers Predictive of Efficacy Betablockers in PEComa and Vascular Pediatric Tumors	Completed	NCT02334930
22	Survival After Hepatectomy for Combined Hepatocellular Cholagiocarcinoma	Completed	NCT03178409
23	A Pilot Study of Combined Immunochemotherapy Followed by Reduced Dose RT for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma	Completed	NCT00594815		Cytarabine, Leucovorin, Methotrexate, Procarbazine, Rituximab, Vincristine
24	Clinicopathological Importance of Colorectal Medullary Carcinoma: Retrospective Cohort Study	Completed	NCT03774862
25	Procurement of Blood and Tissue From Patients With Primary and Metastatic Alveolar Soft Part Sarcoma and Blood From Healthy Controls for In Vitro and In Vivo Model Development	Completed	NCT00340353
26	Natural History and Tissue Acquisition Study of Adrenocortical Carcinoma	Completed	NCT02015026
27	Sentinel Lymph Node Biopsy in Porocarcinoma: A Case Reports	Completed	NCT03647631
28	Retrospective Study of Cases of Small Cell Lung Cancer (SCLC) That Appeared During Treatment of Another Lung Carcinoma With or Without Oncogenic Activation (TransCPC)	Completed	NCT03419286
29	Natural History Study of Children and Adults With Chordoma	Recruiting	NCT03910465
30	International Pediatric Adrenocortical Tumor Registry	Recruiting	NCT00700414
31	Natural History and Biospecimen Acquisition Study for Children and Adults With Rare Solid Tumors	Recruiting	NCT03739827
32	International Pleuropulmonary Blastoma Registry for PPB, DICER1 and Associated Conditions	Recruiting	NCT03382158
33	Neuroblastoma Biology Studies	Recruiting	NCT00904241
34	DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study	Recruiting	NCT01247597
35	Clinico-biological Study/Characterization of Rhabdomyosarcoma in AYA (Adolescents and Young Adults, 15-25-year-old Patients)	Recruiting	NCT03462888
36	Molecular-guided Therapy for the Treatment of Patients With Relapsed and Refractory Childhood Cancers	Active, not recruiting	NCT02162732
37	A Feasibility Trial Using Molecular-Guided Therapy for the Treatment of Patients With Relapsed and Refractory Childhood Cancer	Active, not recruiting	NCT01802567
38	Family Study of Head and Neck Cancers in Taiwan	Active, not recruiting	NCT00342147
39	Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome	Active, not recruiting	NCT00565903
40	Rare Tumor Case Review	Terminated	NCT00229879
41	Topical Anesthesia to Decrease the Trigeminal-Cardiac Reflex During Intra-arterial Injection of Chemotherapy for Retinoblastoma in Children.	Withdrawn	NCT02955524	Early Phase 1	Tetracaine 0.5%;Lidocaine hydrochloride ophthalmic gel 3.5%

Search NIH Clinical Center for Rare Tumor

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Genetic Tests for Rare Tumor

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Anatomical Context for Rare Tumor

MalaCards organs/tissues related to Rare Tumor:

⁴¹

Breast, Pancreas, Liver, Thyroid, Lung, Bone, Kidney

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Publications for Rare Tumor

Articles related to Rare Tumor:

(show top 50) (show all 9727)

#	Title	Authors	PMID	Year
1	Myoepithelioma of the soft tissue: A systematic review of clinical reports. ³⁸	Rastrelli M...Rossi CR	31085025	2019
2	68Ga-NOTA-Aca-BBN(7-14) PET imaging of GRPR in children with optic pathway glioma. ³⁸	Zhang J...Chen X	31270559	2019
3	Papillary Carcinoma of Stensen's Duct with Intestinal Differentiation. ³⁸	Mostafa ME...Giorgadze T	29774486	2019
4	Schwannoma masquerading as adrenocortical tumor: A case report and review of literature. ³⁸	Shabana W...Al-Tartir T	31297325	2019
5	Suprasellar ganglioglioma presenting as a middle cerebral artery infarction. ³⁸	Pastor L...Arraez MA	31289852	2019
6	Collision of Subungual Neurofibroma and Onychomatricoma: S100 Positivity as a Clue. ³⁸	Llamas-Velasco M...Perez-Gonzalez YC	30730391	2019
7	Adrenocortical carcinoma - towards genomics guided clinical care. ³⁸	Crona J...Beuschlein F	31147626	2019
8	Intracranial Extraskeletal Mesenchymal Chondrosarcoma: Case Report and Review of the Literature of Reported Cases in Adults and Children. ³⁸	Shabani S...Foy A	31158544	2019
9	Epstein-Barr Virus-Positive Large Cell Neuroendocrine Carcinoma of the Nasopharynx: Report of One Case and Review of the Literature. ³⁸	Cai Z...Zhu H	30191506	2019
10	Primary, Dural-Based, Ewing Sarcoma Manifesting with Seizure Activity: Presentation of a Rare Tumor Entity with Literature Review. ³⁸	Panagopoulos D...Sfakianos G	31203070	2019
11	Phosphaturic Mesenchymal Tumor of Soft Tissue of the Foot: Report of a Case With Review of the Literature. ³⁸	Bisceglia M...Scillitani A	31261249	2019
12	18F-FDG PET/CT in Oral Cuniculatum Carcinoma. ³⁸	Dejust S...Morland D	31246683	2019
13	Human Papillomavirus-Related Multiphenotypic Sinonasal Carcinoma with Unique HPV type 52 Association: A Case Report with Review of Literature. ³⁸	Adamane SA...Bal M	30259271	2019
14	Laryngeal reconstruction for recurrent desmoid tumor using three-dimensional modeling: A unique approach for a rare tumor. ³⁸	Tracy LF...Shah RN	30585331	2019
15	Incidental Finding of Gastric Schwannoma in a Renal Failure Patient - Managed by a Minimally Invasive Procedure: Report of a Rare Case. ³⁸	Mujtaba MA...Zurkovsky E	31434865	2019
16	Genetic Changes of P53 and Kras in Gallbladder Carcinoma in Kumaon Region of Uttarakhand. ³⁸	Shukla SK...Pant P	31396884	2019
17	What can independent research for mesothelioma achieve to treat this orphan disease? ³⁸	Guazzelli A...Mutti L	31262194	2019
18	[Microcystic serous cystadenoma: An uncommon neoplasm of pancreas. Report of two cases]. ³⁸	Legrand M...Michenet P	30711334	2019
19	True MEN1 or phenocopy? Evidence for geno-phenotypic correlations in MEN1 syndrome. ³⁸	Kovesdi A...Grolmusz VK	31044390	2019
20	Resection of a huge mediastinal well-differentiated liposarcoma involving left thoracic cavity. ³⁸	Zhang M...Wei Z	31387607	2019
21	Fine-needle aspiration cytology of the apocrine variant of epithelial-myoepithelial carcinoma. ³⁸	Perez D...Naous R	31433568	2019
22	Rare cancers in childhood and adolescence in Brazil: First report of data from 19 population-based cancer registries. ³⁸	Balmant NV...Gatta G	31013367	2019
23	An update on emerging drugs in osteosarcoma: towards tailored therapies? ³⁸	Hattinger CM...Serra M	31401903	2019
24	Combined Modality Management of Sinonasal Anaplastic Lymphoma Kinase-Positive Anaplastic Large Cell Lymphoma in a Young Adult-Report of a Rare Case. ³⁸	Biswas A...Sharma A	30994389	2019
25	Synthesis of novel benzothiazole amides: Evaluation of PPAR activity and anti-proliferative effects in paraganglioma, pancreatic and colorectal cancer cell lines. ³⁸	Ammazzalorso A...Amoroso R	31272790	2019
26	Esthesioneuroblastoma on 68Ga DOTANOC PET/CT. ³⁸	Tripathy S...Shamim SA	31274630	2019
27	Clinicopathological features and survival for gallbladder NEN: A population-based study. ³⁸	Cen D...Liang Y	31398710	2019
28	Meningeal metastasis of a malignant peritoneal mesothelioma: A case report and literature review. ³⁸	Jiang Y...Liu Y	31411522	2019
29	Current Treatment Options in Gastroenteropancreatic Neuroendocrine Carcinoma. ³⁸	Thomas KEH...Ramirez RA	30635447	2019
30	Precise Size-Based Cell Separation via the Coupling of Inertial Microfluidics and Deterministic Lateral Displacement. ³⁸	Xiang N...Ni Z	31304740	2019
31	AYA testis cancer: The unmet challenge. ³⁸	Stoneham S...Frazier L	31066223	2019
32	Efficacy and safety of apatinib in advanced sarcoma: an open-label, nonrandomized, single-center study of 45 patients. ³⁸	Weitao Y...Jiaqiang W	31305297	2019
33	Imaging and Surgical Treatment of Primary Pulmonary Artery Sarcoma. ³⁸	Wyler von Ballmoos MC...Reardon MJ	30535656	2019
34	Clinico-pathological features of gynecological myopericytoma: a challenging diagnosis in an exceptional location. ³⁸	Borella F...Benedetto C	31410559	2019
35	Gastric Perivascular Epithelioid Cell Tumor (PEComa). ³⁸	Xu J...Yang W	31141597	2019
36	Cervical Mesonephric Adenocarcinoma With Novel FGFR2 Mutation. ³⁸	Skala SL...Cho KR	31335448	2019
37	[18F]fluorodeoxyglucose-positron emission tomography and glucose-transporter type 1 (GLUT-1) expression in untreated primary small bowel adenocarcinoma. ³⁸	Hauser T...Kreissl MC	31271267	2019
38	Gastric schwannoma with high accumulation on fluorodeoxyglucose-positron emission tomography resected by non-exposed endoscopic wall-inversion surgery. ³⁸	Sugiyama T...Kasugai K	31270750	2019
39	Cytological features of a renal angiomyolipoma in a child-A case report. ³⁸	Jain K...Datta C	31293099	2019
40	Thyroid-Like Follicular Renal Cell Carcinoma Arising Within Benign Mixed Epithelial and Stromal Tumor. ³⁸	Tretiakova MS...Tykodi SS	31342803	2019
41	Primary adrenal schwannoma: a series of 31 cases emphasizing their clinicopathologic features and favorable prognosis. ³⁸	Zhou J...Wang C	31278687	2019
42	Simultaneous gastric adenosquamous carcinoma and gastric carcinoma with lymphoid stroma: A case report. ³⁸	Miyake H...Tsuta K	31289682	2019
43	Clinical silence of pulmonary lymphoepithelioma-like carcinoma with subcutaneous metastasis: a case report. ³⁸	Shima T...Uchiyama K	31340830	2019
44	Primary gastric choriocarcinoma - a rare and aggressive tumor with multilineage differentiation: A case report. ³⁸	Gurzu S...Jung I	31417929	2019
45	[New system combining Hyams grading system and modified Kadish stage to evaluate the progress of esthesioneuroblastoma]. ³⁸	Lai YY...Shi JB	31327194	2019
46	Prognosis and prognostic factors of esophageal spindle cell carcinoma treated by esophagectomy: a retrospective single-institution analysis. ³⁸	Hashimoto M...Hosokawa M	30937574	2019
47	Effect of Adjuvant Therapy on Oncologic Outcomes of Surgically Confirmed Stage I Uterine Carcinosarcoma: a Turkish Gynecologic Oncology Study ³⁸	Kimyon Comert G...Yuce K	30873825	2019
48	Outcome of Metastatic and Recurrent Ovarian Dysgerminoma Using Radiation Therapy and Chemotherapy in a Dog. ³⁸	Wilcox CL...Willcox JL	31099610	2019
49	Diagnostic evaluation and treatment of primary breast osteosarcoma: A case report. ³⁸	Burk KS...Porembka JH	31077474	2019
50	Multimodality-imaging manifestations of primary renal-allograft synovial sarcoma: First case report and literature review. ³⁸	Xu RF...Qian LX	31367627	2019

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Genes for Rare Tumor

Genes related to Rare Tumor (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	EWSR1	EWS RNA Binding Protein 1	Protein Coding	17.33	GeneCards inferred via : Disorders (show sections)
2	RET	Ret Proto-Oncogene	Protein Coding	17.33	GeneCards inferred via : Disorders (show sections)
3	SST	Somatostatin	Protein Coding	16.53	GeneCards inferred via : Publications (show sections)
4	ACTC1	Actin Alpha Cardiac Muscle 1	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
5	CR2	Complement C3d Receptor 2	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
6	DES	Desmin	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
7	FCER2	Fc Fragment Of IgE Receptor II	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
8	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
9	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
10	LATS2	Large Tumor Suppressor Kinase 2	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
11	MMP2	Matrix Metallopeptidase 2	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
12	NF2	Neurofibromin 2	Protein Coding	16.18	GeneCards inferred via : Publications (show sections)
13	FSCN1	Fascin Actin-Bundling Protein 1	Protein Coding	6.18	GeneCards inferred via : Publications (show sections)

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Variations for Rare Tumor

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Expression for Rare Tumor

Search GEO for disease gene expression data for Rare Tumor.

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Pathways for Rare Tumor

Pathways related to Rare Tumor according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cytokine Signaling in Immune system ⁶⁶ Show member pathways Signaling by Interleukins ⁶⁶	12.84	RET MMP2 KIT HLA-DRB1 FSCN1 FCER2
2	Cytoskeletal Signaling ⁴	11.95	NF2 FSCN1 DES ACTC1
3	Interleukin-4 and 13 signaling ⁶⁶	11.55	MMP2 FSCN1 FCER2
4	Hematopoietic cell lineage ³⁷	10.91	KIT HLA-DRB1 FCER2 CR2
5	B Cell Development Pathways ⁶⁵	10.86	KIT FCER2 CR2
6	Hippo signaling pathway - multiple species ³⁷	10.83	NF2 LATS2

Sources

GO Terms for Rare Tumor

Cellular components related to Rare Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	plasma membrane	GO:0005886	9.91	RET NF2 MMP2 KIT HLA-DRB1 FCER2
2	receptor complex	GO:0043235	9.5	RET KIT CR2
3	lamellipodium	GO:0030027	9.33	NF2 FSCN1 ACTC1
4	cell-cell junction	GO:0005911	9.13	KIT FSCN1 DES
5	filopodium	GO:0030175	8.8	NF2 FSCN1 ACTC1

Biological processes related to Rare Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytokine-mediated signaling pathway	GO:0019221	8.92	MMP2 KIT FSCN1 FCER2

Sources

Sources for Rare Tumor

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ TGDB

⁷¹ Tocris

⁷² UMLS

⁷³ UMLS via Orphanet

⁷⁴ UniProtKB/Swiss-Prot

⁷⁵ Wikipedia