Rare Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: RRT020 MIFTS: 41	Rare Tumor Categories: Cancer diseases, Eye diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs Expand all tables

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Aliases & Classifications for Rare Tumor

MalaCards integrated aliases for Rare Tumor:

Name: Rare Tumor ⁵⁸

Rare Neoplasm ⁵⁸

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Eye diseases

See all MalaCards categories (disease lists)

External Ids:

UMLS via Orphanet ⁷² C0375111

Orphanet ⁵⁸ ORPHA98057

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Summaries for Rare Tumor

MalaCards based summary : Rare Tumor, also known as rare neoplasm, is related to desmoplastic small round cell tumor and dermatofibrosarcoma protuberans. An important gene associated with Rare Tumor is EWSR1 (EWS RNA Binding Protein 1), and among its related pathways/superpathways are Cytokine Signaling in Immune system and Cytoskeletal Signaling. The drugs leucovorin and Methylcobalamin have been mentioned in the context of this disorder. Affiliated tissues include breast, pancreas and thyroid, and related phenotypes are homeostasis/metabolism and mortality/aging

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Related Diseases for Rare Tumor

Diseases in the Rare Tumor family:

Rare Eye Tumor

Diseases related to Rare Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 679)

#	Related Disease	Score	Top Affiliating Genes
1	desmoplastic small round cell tumor	32.3	EWSR1 DES
2	dermatofibrosarcoma protuberans	31.7	KIT DES ACTC1
3	spindle cell sarcoma	30.4	NF2 DES ACTC1
4	fibromatosis	30.2	DES ACTC1
5	leiomyosarcoma	30.2	KIT DES ACTC1
6	lipomatosis, multiple	30.2	KIT EWSR1 DES
7	fibrous histiocytoma	30.1	EWSR1 DES ACTC1
8	paraganglioma	30.1	SST RET KIT
9	leiomyoma	30.1	KIT DES ACTC1
10	sarcoma, synovial	30.0	KIT EWSR1 DES
11	hemangioma	30.0	RET KIT ACTC1
12	syringocystadenoma papilliferum	30.0	DES ACTC1
13	spindle cell lipoma	29.9	DES ACTC1
14	rhabdoid tumor predisposition syndrome 1	29.9	DES ACTC1
15	histiocytoma	29.9	KIT EWSR1 ACTC1
16	carcinosarcoma	29.9	KIT DES ACTC1
17	teratoma	29.9	SST KIT ACTC1
18	alveolar soft part sarcoma	29.9	RET DES ACTC1
19	biphasic synovial sarcoma	29.7	EWSR1 DES
20	chondroma	29.7	KIT ACTC1
21	congenital fibrosarcoma	29.7	EWSR1 DES ACTC1
22	angiolipoma	29.7	DES ACTC1
23	glomangioma	29.7	DES ACTC1
24	parachordoma	29.7	DES ACTC1
25	rhabdomyosarcoma	29.7	KIT EWSR1 DES ACTC1
26	desmoid tumor	29.7	KIT DES ACTC1
27	angiomyolipoma	29.7	KIT DES ACTC1
28	neurofibromatosis, type iv, of riccardi	29.6	RET NF2 KIT
29	ossifying fibromyxoid tumor	29.6	DES ACTC1
30	cellular myxoid liposarcoma	29.6	KIT EWSR1
31	hemangiopericytoma, malignant	29.6	KIT DES ACTC1
32	neurilemmoma	29.6	NF2 KIT DES ACTC1
33	follicular dendritic cell sarcoma	29.6	KIT FCER2 CR2
34	chondromyxoid fibroma	29.6	DES ACTC1
35	bladder leiomyoma	29.6	KIT EWSR1
36	neurofibroma	29.5	NF2 KIT ACTC1
37	myoepithelial carcinoma	29.5	EWSR1 ACTC1
38	ewing sarcoma	29.5	RET KIT EWSR1 DES
39	perivascular epithelioid cell tumor	29.4	KIT DES ACTC1
40	adenosarcoma	29.4	KIT DES ACTC1
41	embryonal sarcoma	29.4	KIT DES
42	mesenchymoma	29.4	KIT DES
43	reticulum cell sarcoma	29.4	FCER2 DES CR2 ACTC1
44	sarcoma	29.2	RET NF2 KIT EWSR1 CR2 ACTC1
45	muscle cancer	29.2	KIT EWSR1 DES
46	constipation	29.2	SST RET KIT EWSR1
47	perineurioma	29.2	KIT ACTC1
48	malignant peripheral nerve sheath tumor	29.1	NF2 KIT ACTC1
49	pleomorphic liposarcoma	29.1	KIT EWSR1 DES ACTC1
50	smooth muscle tumor	29.1	KIT DES CR2 ACTC1

Graphical network of the top 20 diseases related to Rare Tumor:

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Symptoms & Phenotypes for Rare Tumor

MGI Mouse Phenotypes related to Rare Tumor:

⁴⁵

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	homeostasis/metabolism	MP:0005376	9.85	ACTC1 CR2 DES FCER2 KIT LATS2
2	mortality/aging	MP:0010768	9.7	ACTC1 CR2 DES FCER2 FSCN1 KIT
3	muscle	MP:0005369	9.1	ACTC1 DES KIT LATS2 MMP2 RET

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Drugs & Therapeutics for Rare Tumor

Drugs for Rare Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 118)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

leucovorin

Approved

Phase 2, Phase 3

58-05-9

6006 143

Methylcobalamin

Approved, Investigational

Phase 2, Phase 3

13422-55-4

Hydroxocobalamin

Approved

Phase 2, Phase 3

13422-51-0

11953898 15589840

Bevacizumab

Approved, Investigational

Phase 2, Phase 3

216974-75-3

Pemetrexed

Approved, Investigational

Phase 2, Phase 3

150399-23-8, 137281-23-3

446556 60843

Folic acid

Approved, Nutraceutical, Vet_approved

Phase 2, Phase 3

59-30-3

6037

Cyanocobalamin

Approved, Nutraceutical

Phase 2, Phase 3

68-19-9

44176380

Cobalamin

Experimental

Phase 2, Phase 3

13408-78-1

6857388

Folic Acid Antagonists

Phase 2, Phase 3

Vitamin B9

Phase 2, Phase 3

Vitamin B Complex

Phase 2, Phase 3

Folate

Phase 2, Phase 3

Vitamins

Phase 2, Phase 3

Vitamin B 12

Phase 2, Phase 3

Vitamin B12

Phase 2, Phase 3

Vincristine

Approved, Investigational

Phase 2

2068-78-2, 57-22-7

5978

Doxorubicin

Approved, Investigational

Phase 2

23214-92-8

31703

Etoposide

Approved

Phase 2

33419-42-0

36462

Mitotane

Approved

Phase 2

53-19-0

4211

Sirolimus

Approved, Investigational

Phase 2

53123-88-9

5284616 6436030 46835353

Palbociclib

Approved, Investigational

Phase 2

571190-30-2

11431660 5005498 5330286

Olaparib

Approved

Phase 2

763113-22-0

23725625

Dabrafenib

Approved, Investigational

Phase 2

1195765-45-7

44462760 44516822

afatinib

Approved

Phase 2

850140-72-6, 439081-18-2

10184653

Everolimus

Approved

Phase 2

159351-69-6

6442177 70789204

Miconazole

Approved, Investigational, Vet_approved

Phase 2

22916-47-8

4189

Vemurafenib

Approved

Phase 2

918504-65-1

23252090 42611257

Gefitinib

Approved, Investigational

Phase 2

184475-35-2

123631

Trastuzumab

Approved, Investigational

Phase 2

180288-69-1

9903

Cisplatin

Approved

Phase 2

15663-27-1

84093 441203 2767

Durvalumab

Approved, Investigational

Phase 2

1428935-60-7

Ifosfamide

Approved

Phase 2

3778-73-2

3690

Paclitaxel

Approved, Vet_approved

Phase 2

33069-62-4

36314

Tamoxifen

Approved

Phase 2

10540-29-1

2733526

Progesterone

Approved, Vet_approved

Phase 2

57-83-0

5994

rituximab

Approved

Phase 2

174722-31-7

10201696

Rucaparib

Approved, Investigational

Phase 2

283173-50-2

9931954

Oxaliplatin

Approved, Investigational

Phase 2

61825-94-3

5310940 9887054 6857599 43805

Gemcitabine

Approved

Phase 2

95058-81-4

60750

Dopamine

Approved

Phase 2

51-61-6, 62-31-7

681

Salmon Calcitonin

Approved, Investigational

Phase 2

47931-85-1

16129616

Levodopa

Approved

Phase 2

59-92-7

6047

Imiquimod

Approved, Investigational

Phase 1, Phase 2

99011-02-6

57469

Tremelimumab

Investigational

Phase 2

745013-59-6

Calcitonin gene-related peptide

Investigational

Phase 2

83652-28-2

Antimitotic Agents

Phase 2

Liposomal doxorubicin

Phase 2

31703

Etoposide phosphate

Phase 2

Topoisomerase Inhibitors

Phase 2

polysaccharide-K

Phase 2

Interventional clinical trials:

(show all 43)

#	Name	Status	NCT ID	Phase	Drugs
1	A Phase II-III Randomized Trial Pemetrexed-Cisplatin Chemotherapy With or Without Bevacizumab (Avastin), 15 mg/kg, for Malignant Pleural Mesothelioma (MPM)	Completed	NCT00651456	Phase 2, Phase 3	Standard Chemotherapy (Pemetrexed and Cisplatin);Standard Chemotherapy (Pemetrexed and Cisplatin) + Bevacizumab
2	Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy (HIPEC) for Adrenocortical Carcinoma	Completed	NCT01833832	Phase 2	Cisplatin;sodium thiosulfate
3	A Study of Combination Chemotherapy & Surgical Resection in the Tx of Adrenocortical Cancer: Mitotane & Continuous Infusion Doxorubicin, Vincristine & Etoposide w/the P-glycoprotein Antagonist, Tariquidar (XR9576), Before & After Surgical Resection	Completed	NCT00071058	Phase 2	XR9576 (Tariquidar)
4	Efficacy and Safety of Targeted Precision Therapy in Refractory Tumor With Druggable Molecular Event	Recruiting	NCT03239015	Phase 2	Gefitinib;Erlotinib;Afatinib;Trastuzumab;Oxazolidine;Olaparib;Everolimus;Cabozantinib;Vemurafenib;Dabrafenib;Palbociclib
5	Phase II Trial of Surgical Resection and Heated Intraperitoneal Peritoneal Chemotherapy (HIPEC) for Adrenocortical Carcinoma	Recruiting	NCT03127774	Phase 2	Cisplatin;Sodium thiosulfate
6	A Phase II Study of Durvalumab (MEDI4736) (Anti-PD-L1 Antibody) in Combination With Tremelimumab (Anti-CTLA-4 Antibody) in Subjects With Advanced Rare Solid Tumors	Recruiting	NCT02938793	Phase 2	Durvalumab;Tremelimumab
7	Prospective Phase II Study Evaluating a Multimodal Care of Inguinal Node Metastasis in Squamous Cell Carcinoma of the Penis by Bilateral Lymphadenectomy and Chemotherapy TIP	Recruiting	NCT02817958	Phase 2	Chemotherapy TIP
8	Phase II Study of Hormone Therapy With Tamoxifen in Patients With Well Differentiated Neuroendocrine Tumors and Hormone Receptor Positive Expression	Recruiting	NCT03870399	Phase 2	Tamoxifen
9	Bendamustine and Rituximab for the Treatment of Splenic Marginal Zone Lymphoma. The International Extranodal Lymphoma Study Group (IELSG) 36 Phase II Prospective Study	Active, not recruiting	NCT02853370	Phase 2	Bendamustine and Rituximab
10	A Phase 2 Multicenter, Open-label Study of Rucaparib as Treatment for Solid Tumors Associated With Deleterious Mutations in Homologous Recombination Repair Genes	Not yet recruiting	NCT04171700	Phase 2	Rucaparib
11	A Single-center, Open Label Study for Evaluation of the Safety and Efficacy of Oshadi D and Oshadi R for Malignant Mesothelioma Treatment - A Phase IIa Study	Suspended	NCT01627795	Phase 1, Phase 2	Oshadi D and Oshadi R
12	Open Labeled Phase II Study Evaluating Efficacy and Safety of Chemotherapy With Gemcitabine - Oxaliplatin Combination for Advanced Refractory Thyroid Cancer Patients	Terminated	NCT02472080	Phase 2	gemcitabine -oxaliplatine combination
13	Efficacy and Tolerance of RADIOEMBOLIZATION for Patients With Unresectable Intrahepatic Cholangiocarcinoma With Tumor Progression After First-line Therapy	Terminated	NCT01383746	Phase 1, Phase 2
14	Clinical Evaluation of 18F-DOPA Positron Emission Tomography in Medullary Thyroid Cancer.	Terminated	NCT00647140	Phase 2
15	Phase I/II Study of Peptide Vaccination Associated With GM-CT-01, a Galactomannan Oligomer That Inhibits Galectin-3, in Patients With Advanced Metastatic Melanoma	Terminated	NCT01723813	Phase 1, Phase 2
16	Phase I/II Study of Peptide Vaccination Associated With Tumoral Immunomodulation With Proinflammatory Cytokines and Imiquimod in Patients With Advanced Metastatic Melanoma	Terminated	NCT01191034	Phase 1, Phase 2	Vaccine MAGE-3.A1 peptide, or the NA17.A2 peptide + IL-2, IFN-α and GMCSF, Imiquimod.
17	Phase I/II Study of Xeloda and Gleevec in Patients With Advanced Solid Tumors	Completed	NCT00183833	Phase 1	capecitabine, imatinib mesylate
18	Imatinib Mesylate And Cyclophosphamide In Metronomic Administration: Dose Escalation Study Of Imatinib Mesylate in Patient With Rare Tumor (Phase I Study)	Completed	NCT01046487	Phase 1	Imatinib mesylate, Cyclophosphamide (Dosing level 1 );Imatinib mesylate, Cyclophosphamide (Dosing level 2);Imatinib mesylate, Cyclophosphamide (Dosing level 3)
19	A Phase I Dose Escalation Study of Autologous Expanded Natural Killer (NK) Cells for Immunotherapy of Relapsed Refractory Neuroblastoma With Dinutuximab +/- Lenalidomide	Recruiting	NCT02573896	Phase 1	Ch14.18;Lenalidomide
20	A Phase I/II Trial of IL-13-PE in Patients With Treatment Refractory Malignancies With a Focus on Metastatic and Locally Advanced Adrenocortical Carcinoma	Terminated	NCT01832974	Phase 1	IL-13-PE
21	Contribution of F18-FDG PET/CT to the Early Assessment of Pazopanib Therapy Efficacy in Advanced Soft Tissue Sarcoma	Unknown status	NCT01594203
22	Evaluation of New Biomarkers Predictive of Efficacy Betablockers in PEComa and Vascular Pediatric Tumors	Completed	NCT02334930
23	Survival After Hepatectomy for Combined Hepatocellular Cholagiocarcinoma	Completed	NCT03178409
24	A Pilot Study of Combined Immunochemotherapy Followed by Reduced Dose RT for Patients With Newly Diagnosed Primary Central Nervous System Lymphoma	Completed	NCT00594815		Cytarabine, Leucovorin, Methotrexate, Procarbazine, Rituximab, Vincristine
25	Clinicopathological Importance of Colorectal Medullary Carcinoma: Retrospective Cohort Study	Completed	NCT03774862
26	Procurement of Blood and Tissue From Patients With Primary and Metastatic Alveolar Soft Part Sarcoma and Blood From Healthy Controls for In Vitro and In Vivo Model Development	Completed	NCT00340353
27	Natural History and Tissue Acquisition Study of Adrenocortical Carcinoma	Completed	NCT02015026
28	Sentinel Lymph Node Biopsy in Porocarcinoma: A Case Reports	Completed	NCT03647631
29	Retrospective Study of Cases of Small Cell Lung Cancer (SCLC) That Appeared During Treatment of Another Lung Carcinoma With or Without Oncogenic Activation (TransCPC)	Completed	NCT03419286
30	Natural History Study of Children and Adults With Chordoma	Recruiting	NCT03910465
31	International Pediatric Adrenocortical Tumor Registry	Recruiting	NCT00700414
32	Natural History and Biospecimen Acquisition Study for Children and Adults With Rare Solid Tumors	Recruiting	NCT03739827
33	Neuroblastoma Biology Studies	Recruiting	NCT00904241
34	International Pleuropulmonary Blastoma Registry for PPB, DICER1 and Associated Conditions	Recruiting	NCT03382158
35	Clinico-biological Study/Characterization of Rhabdomyosarcoma in AYA (Adolescents and Young Adults, 15-25-year-old Patients)	Recruiting	NCT03462888
36	DICER1-Related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study	Recruiting	NCT01247597
37	A Feasibility Trial Using Molecular-Guided Therapy for the Treatment of Patients With Relapsed and Refractory Childhood Cancer	Active, not recruiting	NCT01802567
38	Molecular-guided Therapy for the Treatment of Patients With Relapsed and Refractory Childhood Cancers	Active, not recruiting	NCT02162732
39	Family Study of Head and Neck Cancers in Taiwan	Active, not recruiting	NCT00342147
40	Elucidating the Genetic Basis of the Pleuropulmonary Blastoma (PPB) Familial Cancer Syndrome	Active, not recruiting	NCT00565903
41	Measurement of Circulating Tumor Cells in Prostate Cancer	Not yet recruiting	NCT04101305
42	Rare Tumor Case Review	Terminated	NCT00229879
43	Topical Anesthesia to Decrease the Trigeminal-Cardiac Reflex During Intra-arterial Injection of Chemotherapy for Retinoblastoma in Children.	Withdrawn	NCT02955524	Early Phase 1	Tetracaine 0.5%;Lidocaine hydrochloride ophthalmic gel 3.5%

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Genetic Tests for Rare Tumor

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Anatomical Context for Rare Tumor

MalaCards organs/tissues related to Rare Tumor:

⁴⁰

Breast, Pancreas, Thyroid, Liver, Lung, Bone, Kidney

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Publications for Rare Tumor

Articles related to Rare Tumor:

(show top 50) (show all 9983)

#	Title	Authors	PMID	Year
1	Primary angiosarcoma of the breast: Case report of a rare vascular tumor. ⁶¹	Abdelhady AM...Germaine P	31993096	2020
2	Dilemmas in Diagnosis and Management of Gastroenteropancreatic Mixed Neuroendocrine Non-neuroendocrine Neoplasms: First Single-Centre Report from India. ⁶¹	Desai GS...Jagannath P	30784017	2020
3	Diagnosis of Mesothelioma. ⁶¹	Fels Elliott DR...Jones KD	32005436	2020
4	Leiomyosarcoma of the skin: review of the literature with an emphasis on prognosis and management. ⁶¹	Kazlouskaya V...Khachemoune A	31729020	2020
5	8p deletions in renal cell carcinoma are associated with unfavorable tumor features and poor overall survival. ⁶¹	Eichenauer T...Clauditz TS	31757738	2020
6	Thyroid-Like Follicular Renal Cell Carcinoma Arising Within Benign Mixed Epithelial and Stromal Tumor. ⁶¹	Tretiakova MS...Tykodi SS	31342803	2020
7	Angiomatosis of the Urinary Bladder: A New Anatomic Location for a Rare Tumor. ⁶¹	Kloniecke E...Zeltser I	31454655	2020
8	Exploring heterogeneity of adrenal cortical tumors in children: The French pediatric rare tumor group (Fracture) experience. ⁶¹	Picard C...Orbach D	31738008	2020
9	Primary Angiosarcoma of the Kidney: Literature Review of a Rare Nosologic Entity. ⁶¹	Mastoraki A...Liakakos T	32014903	2020
10	Precision medicine in Ewing sarcoma: a translational point of view. ⁶¹	Gargallo P...Canete A	32026343	2020
11	Giant cell tumor of soft tissue of the breast: Case report with H3F3A mutation analysis and review of the literature. ⁶¹	Luangxay T...Akiyama F	31784095	2020
12	A Rare Pulmonary Artery Sarcoma Masquerading as Pulmonary Embolus. ⁶¹	Skiba R...Merry C	31279785	2020
13	Primary pulmonary myxoid sarcoma with EWSR1-CREB1 fusion: a case report and review of the literature. ⁶¹	Chen Z...Shi H	32039736	2020
14	Surgical recurrence of solitary fibrous tumor of the pleura treated with microwave (MW) thermoablation: A case report. ⁶¹	Fiore F...Somma F	31876364	2020
15	Cutaneous Syncytial Myoepithelioma: A Nondescript Skin Tumor With Serious Diagnostic Pitfalls. ⁶¹	Wales C...Hinds B	31587595	2020
16	Primary Clear Cell Adenocarcinoma of the Head and Neck: A Population-Based Analysis. ⁶¹	Mukdad L...St John MA	32013719	2020
17	Intracholecystic Papillary-Tubular Neoplasms (ICPN) of the Gallbladder. ⁶¹	Saritas AG...Aydin I	32039884	2020
18	Cervical Vagal Schwannoma Causing Asymptomatic Internal Carotid Artery Compression. ⁶¹	Keshelava G...Robakidze Z	31629844	2020
19	Gastric schwannoma with high accumulation on fluorodeoxyglucose-positron emission tomography resected by non-exposed endoscopic wall-inversion surgery. ⁶¹	Sugiyama T...Kasugai K	31270750	2020
20	The clinicoradiological features and surgical outcomes of primary intracranial fibrosarcoma: a single-institute experience with a systematic review. ⁶¹	Ma XJ...Wu Z	32036505	2020
21	Merkel Cell Polyomavirus-Positive Panniculitic Merkel Cell Carcinoma: A Rare Neoplasm of Unknown Histogenesis. ⁶¹	Saggini A...Cota C	30908296	2020
22	Epithelial myoepithelial carcinoma of the parotid gland: A rare tumor with oncocytic changes. ⁶¹	Inan HC...Issin G	32031104	2020
23	Desmoplastic small round-cell tumour of the peritoneal cavity: case report and literature review. ⁶¹	Tsoukalas N...Sambaziotis D	31973562	2020
24	Conjunctival Melanoma: Current Treatments and Future Options. ⁶¹	Grimes JM...Marr BP	31965542	2020
25	Signet-ring cell carcinoma of the ampulla of Vater: a case diagnosed via repeated biopsies. ⁶¹	Ikeda C...Ueno Y	31981088	2020
26	A Phase II Basket Trial of Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors (DART SWOG 1609) in Patients with Non-Pancreatic Neuroendocrine Tumors. ⁶¹	Patel SP...Kurzrock R	31969335	2020
27	Melanotic neuroectodermal tumor of infancy arising from the skull: report of an unusual case, review of the literature, and a diagnostic approach. ⁶¹	Mengide JP...Mantese B	31897638	2020
28	Sarcomatoid chromophobe renal cell carcinoma revealed by acute pyelonephritis in a diabetic patient. ⁶¹	Jouini R...Chadli-Debbiche A	31681535	2020
29	A rare pericytic tumor of the kidney: The first case in Korea. ⁶¹	Chung JW...Kwon TG	31855704	2020
30	Agenesis of the corpus callosum and hepatoblastoma. ⁶¹	Luckie TM...Venkatramani R	31729153	2020
31	Wagner-Meissner neurilemmoma of the lip occurring in a patient with neurofibromatosis type 1: A case report. ⁶¹	Miyasaka C...Tsuta K	31814976	2020
32	Melanotic neuroectodermal tumor of infancy to the skull: case-based review. ⁶¹	Ebel F...Soleman J	31953575	2020
33	Malignant peripheral nerve sheath tumor of the sciatic nerve presenting with leg pain in the setting of lumbar scoliosis and spinal stenosis. ⁶¹	Suratwala SJ...Leone V	31925758	2020
34	Very high rate of false positive biochemical results when screening for pheochromocytoma in a large, undifferentiated population with variable indications for testing. ⁶¹	Kline GA...Sadrzadeh HM	31978379	2020
35	Survival and ocular preservation in a long-term cohort of Japanese patients with retinoblastoma. ⁶¹	Ueda T...Ohga S	31992242	2020
36	A case report of temple squamoid eccrine ductal carcinoma: A diagnostic challenge beneath the tip of the iceberg. ⁶¹	Phan K...Cheung K	31895497	2020
37	Macrofollicular Variant of Follicular Thyroid Carcinoma: A Rare Underappreciated Pitfall in the Diagnosis of Thyroid Carcinoma. ⁶¹	Bongiovanni M...Pusztaszeri M	31701808	2020
38	Images - Oncocytic adrenocortical carcinoma: A rare tumor variant. ⁶¹	Lehr I...Organ M	31658010	2020
39	Adrenocortical carcinoma in a young adult male with chronic urticaria: A case report and literature review. ⁶¹	Moussa Y...Abou Chakra M	31918158	2020
40	Adrenal cortical carcinoma: pathology, genomics, prognosis, imaging features, and mimics with impact on management. ⁶¹	Ahmed AA...Elsayes KM	31894378	2020
41	A Micellar Mitotane Formulation with High Drug-Loading and Solubility: Physico-Chemical Characterization and Cytotoxicity Studies in 2D and 3D In Vitro Tumor Models. ⁶¹	Haider MS...Luxenhofer R	31596553	2020
42	Soft Tissue Special Issue: Fibroblastic and Myofibroblastic Neoplasms of the Head and Neck. ⁶¹	Baranov E...Hornick JL	31950474	2020
43	Multiple recurrences of spindle cell oncocytoma: A case report and literature review. ⁶¹	Chainey J...Das S	31496509	2020
44	Difficult journeys in sarcoma care; socioeconomic disparity added to the multiple challenges of a rare tumor diagnosis. ⁶¹	Nilbert M	31994423	2020
45	Primary cutaneous mucinous carcinoma of the scrotum: A rare tumor at a rare site - A case report and review of literature. ⁶¹	Abiola OO...Lasisi ME	32015625	2020
46	[A rare pathology of the petrous part of the temporal bone: adenoma of the middle ear]. ⁶¹	Sudhoff H...Todt I	31531685	2020
47	A case report of solitary neurofibroma of the Vas deferens. ⁶¹	Abdullah...Xing JP	31763167	2020
48	A case of submandibular desmoplastic small round cell tumor: Diagnostic and management approaches to an atypical presentation of a rare tumor. ⁶¹	Rubinstein JD...Pressey JG	31925924	2020
49	Hepatic epithelioid hemangioendothelioma successfully treated with living donor liver transplantation: A case report and literature review. ⁶¹	Fukuhara S...Ohdan H	31998498	2020
50	The clinicopathological spectrum of pseudomyogenic hemangioendothelioma: report of an additional series with review of the literature. ⁶¹	Sun Y...Wang J	31980959	2020

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Genes for Rare Tumor

Genes related to Rare Tumor (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	EWSR1	EWS RNA Binding Protein 1	Protein Coding	7.32	GeneCards inferred via : Disorders (show sections)
2	RET	Ret Proto-Oncogene	Protein Coding	7.32	GeneCards inferred via : Disorders (show sections)
3	SST	Somatostatin	Protein Coding	6.5	GeneCards inferred via : Publications (show sections)
4	ACTC1	Actin Alpha Cardiac Muscle 1	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
5	CR2	Complement C3d Receptor 2	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
6	DES	Desmin	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
7	FCER2	Fc Fragment Of IgE Receptor II	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
8	FSCN1	Fascin Actin-Bundling Protein 1	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
9	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
10	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
11	LATS2	Large Tumor Suppressor Kinase 2	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
12	MMP2	Matrix Metallopeptidase 2	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)
13	NF2	Neurofibromin 2	Protein Coding	6.16	GeneCards inferred via : Publications (show sections)

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Variations for Rare Tumor

Sources

Expression for Rare Tumor

Search GEO for disease gene expression data for Rare Tumor.

Sources

Pathways for Rare Tumor

Pathways related to Rare Tumor according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Cytokine Signaling in Immune system ⁶⁵ Show member pathways Signaling by Interleukins ⁶⁵	12.84	RET MMP2 KIT HLA-DRB1 FSCN1 FCER2
2	Cytoskeletal Signaling ⁴	11.95	NF2 FSCN1 DES ACTC1
3	Interleukin-4 and 13 signaling ⁶⁵	11.55	MMP2 FSCN1 FCER2
4	Hematopoietic cell lineage ³⁶	10.92	KIT HLA-DRB1 FCER2 CR2
5	B Cell Development Pathways ⁶⁴	10.86	KIT FCER2 CR2
6	Hippo signaling pathway - multiple species ³⁶	10.83	NF2 LATS2

Sources

GO Terms for Rare Tumor

Cellular components related to Rare Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cell-cell junction	GO:0005911	9.33	KIT FSCN1 DES
2	lamellipodium	GO:0030027	9.13	NF2 FSCN1 ACTC1
3	filopodium	GO:0030175	8.8	NF2 FSCN1 ACTC1

Biological processes related to Rare Tumor according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cytokine-mediated signaling pathway	GO:0019221	8.92	MMP2 KIT FSCN1 FCER2

Sources

Sources for Rare Tumor

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia