MCID: RCT017
MIFTS: 40

Rectal Disease

Categories: Gastrointestinal diseases

Aliases & Classifications for Rectal Disease

MalaCards integrated aliases for Rectal Disease:

Name: Rectal Disease 12 15
Rectal Diseases 44 73
Rectal Disorders 43

Classifications:



External Ids:

Disease Ontology 12 DOID:1285
MeSH 44 D012002
SNOMED-CT 68 5964004
UMLS 73 C0034882

Summaries for Rectal Disease

MedlinePlus : 43 The rectum is the lower part of your large intestine where your body stores stool. Problems with rectum are common. They include hemorrhoids, abscesses, incontinence and cancer. Many people are embarrassed to talk about rectal troubles. But seeing your doctor about problems in this area is important. This is especially true if you have pain or bleeding. Treatments vary depending on the particular problem. NIH: National Institute of Diabetes and Digestive and Kidney Diseases

MalaCards based summary : Rectal Disease, also known as rectal diseases, is related to hemorrhoid and proctitis, and has symptoms including nausea and vomiting, constipation and abdominal pain. An important gene associated with Rectal Disease is MT-TG (Mitochondrially Encoded TRNA Glycine). The drugs Aspirin and Diltiazem have been mentioned in the context of this disorder. Affiliated tissues include colon, kidney and testes.

Wikipedia : 76 The rectum is the final straight portion of the large intestine in humans and some other mammals, and... more...

Related Diseases for Rectal Disease

Diseases related to Rectal Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 39)
# Related Disease Score Top Affiliating Genes
1 hemorrhoid 11.4
2 proctitis 10.9
3 vulva squamous cell carcinoma 10.2 CDKN2A SERPINB3
4 tethered spinal cord syndrome 10.2 KIDINS220 MNX1
5 urethritis 10.2 EXTL3 MT-TG
6 superficial basal cell carcinoma 10.2 TLR7 TLR9
7 anal canal squamous cell carcinoma 10.2 CDKN2A SERPINB3
8 anal canal carcinoma 10.1 CD6 CDKN2A
9 neurogenic bowel 10.1 DCXR KIDINS220
10 fallopian tube disease 10.1 EXTL3 MT-TG MTRR
11 inverted follicular keratosis 10.1 GP5 SALL1
12 tongue disease 10.1 CD6 CDKN2A TLR9
13 cervicitis 10.1 CDKN2A MT-TG
14 cervix uteri carcinoma in situ 10.1 CDKN2A GP5
15 uterus carcinoma in situ 10.1 CDKN2A GP5
16 anus, imperforate 10.1 KIDINS220 MNX1 SALL1 TEF
17 cervix disease 10.1 CDKN2A GP5 TLR9
18 uterine anomalies 10.1 CDKN2A GP5 TLR9
19 female reproductive system disease 10.0 CDKN2A GP5 TLR9
20 anogenital venereal wart 10.0 CDKN2A MID2 TLR7
21 anus cancer 10.0 CD6 CDKN2A DCXR SERPINB3
22 vulvar dystrophy 10.0 CDKN2A LINC01191
23 esophageal disease 10.0 CDKN2A KANTR TEF
24 vulval paget's disease 10.0 CDKN2A LINC01191
25 tabes dorsalis 10.0 EXTL3 KANTR
26 vulva adenocarcinoma 10.0 CDKN2A LINC01191
27 urethral diverticulum 10.0 KIDINS220 KLK3
28 vulva cancer 10.0 CDKN2A LINC01191 SERPINB3
29 reproductive system disease 9.9 CDKN2A GP5 KLK3 TLR9
30 vulvar disease 9.8 CDKN2A GP5 LINC01191 SERPINB3
31 penile disease 9.7 CDKN2A LINC01191 MID2 TLR7
32 urethral syndrome 9.7 EXTL3 KANTR KIDINS220 KLK3 MT-TG MTRR
33 vaginal disease 9.7 EXTL3 GP5 LINC01191 TLR7
34 prostate cancer 9.6
35 herpangina 9.6 GP5 LINC01191 MID2 TLR7
36 lymphoma 9.6
37 internal hemorrhoid 9.6
38 plasmablastic lymphoma 9.6
39 anus disease 8.3 CDKN2A CECR2 DCXR EXTL3 GP5 KANTR

Graphical network of the top 20 diseases related to Rectal Disease:



Diseases related to Rectal Disease

Symptoms & Phenotypes for Rectal Disease

UMLS symptoms related to Rectal Disease:


nausea and vomiting, constipation, abdominal pain, diarrhea, icterus, rectal tenesmus, dyspepsia, heartburn, pruritus ani, gastrointestinal gas, rectal pain

Drugs & Therapeutics for Rectal Disease

Drugs for Rectal Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 847)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-78-2 2244
2
Diltiazem Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 42399-41-7 39186
3
Iron Approved Phase 4,Phase 3,Phase 2,Not Applicable 7439-89-6 23925
4
Capecitabine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 154361-50-9 60953
5
Epirubicin Approved Phase 4,Phase 2 56420-45-2 41867
6
Ethiodized oil Approved, Investigational Phase 4,Phase 2 8008-53-5
7
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 61825-94-3 43805 6857599 5310940 9887054
8
Raltitrexed Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 112887-68-0 104758
9
leucovorin Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 6006 143
10
Erythromycin Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable 114-07-8 12560
11
Fluorouracil Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-21-8 3385
12
Tegafur Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 17902-23-7 5386
13
Bevacizumab Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 216974-75-3
14
Irinotecan Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 100286-90-6, 97682-44-5 60838
15
Levoleucovorin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 68538-85-2
16
Lidocaine Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable,Early Phase 1 137-58-6 3676
17
Bisacodyl Approved Phase 4,Phase 3,Phase 2,Not Applicable 603-50-9
18
Cetuximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 205923-56-4 56842117 2333
19
Phytonadione Approved, Investigational Phase 4,Phase 2 84-80-0 4812 5284607
20
Bupivacaine Approved, Investigational Phase 4,Phase 3,Phase 2,Not Applicable,Early Phase 1 2180-92-9, 38396-39-3 2474
21
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
22
Iodine Approved, Investigational Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 7553-56-2 807
23
Acetylcholine Approved Phase 4,Phase 3,Phase 2,Not Applicable 51-84-3 187
24 tannic acid Approved Phase 4,Phase 2,Phase 1,Not Applicable
25
Benzocaine Approved, Investigational Phase 4,Phase 2,Phase 1,Not Applicable 94-09-7, 1994-09-7 2337
26
Epinephrine Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 51-43-4 5816
27
Racepinephrine Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 329-65-7 838
28
Heparin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 9005-49-6 772 46507594
29
Adalimumab Approved Phase 4,Phase 3,Not Applicable 331731-18-1 16219006
30
Celecoxib Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1,Not Applicable 169590-42-5 2662
31
Glycerol Approved, Investigational Phase 4,Phase 2,Phase 3,Not Applicable 56-81-5 753
32
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 50-02-2 5743
33
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 1177-87-3
34
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable,Early Phase 1 2078-54-8 4943
35
Zinc Approved, Investigational Phase 4,Phase 1,Phase 2,Not Applicable 7440-66-6
36
Metronidazole Approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 443-48-1 4173
37
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable 22916-47-8 4189
38
Nitroglycerin Approved, Investigational Phase 4,Phase 3,Phase 1,Not Applicable 55-63-0 4510
39
Nitric Oxide Approved Phase 4,Phase 1 10102-43-9 145068
40
Sucralfate Approved Phase 4 54182-58-0 0
41
Morphine Approved, Investigational Phase 4,Phase 3 57-27-2 5288826
42
Ketamine Approved, Vet_approved Phase 4,Not Applicable,Early Phase 1 6740-88-1 3821
43
Diclofenac Approved, Vet_approved Phase 4,Phase 2 15307-86-5 3033
44
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 2,Not Applicable,Early Phase 1 437-38-7 3345
45
Prilocaine Approved Phase 4,Phase 3 721-50-6 4906
46
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 119141-88-7 4594 9579578
47
Magnesium citrate Approved Phase 4,Phase 3,Not Applicable 3344-18-1
48
Tacrolimus Approved, Investigational Phase 4 104987-11-3 445643 439492
49
Dexmedetomidine Approved, Vet_approved Phase 4 113775-47-6 68602 5311068
50
Ertapenem Approved, Investigational Phase 4 153832-46-3 150610

Interventional clinical trials:

(show top 50) (show all 4616)
# Name Status NCT ID Phase Drugs
1 The Risk of Bleeding After Removal of Large Colorectal Polyps in Patients Taking Aspirin Unknown status NCT01549418 Phase 4 Aspirin (ASA);Placebo
2 Pediatrics Anal Fissures Treatment With Polyethylene Glycol Unknown status NCT02419534 Phase 4 Polyethylene glycol;Polyethylene glycol with Diltiazem
3 Intravenous Iron for Correction of Anaemia After Colorectal Surgery Unknown status NCT02999217 Phase 4 Iron isomaltoside;Saline
4 Maintenance Treatment With Capecitabine Metronomic Chemotherapy and Chinese Traditional Medicine in Metastatic Colorectal Cancer Unknown status NCT02575378 Phase 4 Metronimic chemotherapy plus Chinese Traditional Medicine;Metronimic chemotherapy
5 Oxaliplatin and Raltitrexed Treatment of Colorectal Cancer With Liver Metastases Unknown status NCT02557490 Phase 4 oxaliplatin and raltitrexed
6 A Prospective Evaluation of the Strattice-LIFT to Treat Anal Fistula Unknown status NCT02423330 Phase 4
7 Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutation in Familial Adenomatous Polyposis-minors' Adjusted Version Unknown status NCT02354560 Phase 4 Erythromycin
8 HAL-RAR Versus Hemorrhoidectomy in the Treatment of Grade III-IV Hemorrhoids. Prospective, Randomized Trial Unknown status NCT02216305 Phase 4
9 Erythromycin Treatment for Readthrough of APC Gene Stop Codon Mutations in Familial Adenomatous Polyposis Unknown status NCT02175914 Phase 4 Erythromycin
10 Intraoperative Intraportal Chemotherapy Combined With Adjuvant Chemotherapy for Stage II and III Colorectal Cancer Unknown status NCT01972503 Phase 4 5-FU and oxaliplatin
11 Avastin in Combination With Chemotherapy for the Treatment of Metastatic Colorectal Cancer Unknown status NCT01972490 Phase 4 avastin+chemotherapy of mFOLFOX6 or FOLFIRI;chemotherapy of mFOLFOX6 or FOLFIRI
12 NK Activity Modulation Induced by Intravenous Lidocaine During Colorectal Laparoscopic Surgery Unknown status NCT01841294 Phase 4 Intravenous Lidocaine;Normal saline infusion
13 Participation and Detection Rate Diagnostic of a Colorectal Cancer Screening Program: CT Colonography vs. Flexible Sigmoidoscopy Unknown status NCT01739608 Phase 4
14 Efficacy and Patient Satisfaction of Miralax and Gatorade Versus Movi Prep Unknown status NCT01695863 Phase 4 comparing 2 drugs on their effect on the bowel preparation for colonoscopy
15 Cetuximab in Combination With Chemotherapy for the Treatment of Metastatic Colorectal Cancer Unknown status NCT01564810 Phase 4 Cetuximab;chemotherapy of mFOLFOX6 or FOLFIRI
16 FOLFIRI in Combination With Cetuximab in the First-line Treatment of Metastatic Colorectal Cancer Including a Regular Dermal Prophylaxis to Prevent Acneiforme Follicular Exanthema Unknown status NCT01315990 Phase 4 FOLFIRI + Cetuximab
17 New Adjuvant Chemotherapy of Non Resectable Liver Metastasis of Colorectal Cancer Without Bleeding, Obstruction Unknown status NCT01307878 Phase 4 chemotherapy ± targeted therapy
18 Continuous Infusion of Local Anesthetic for Optimal Post Operative Pain Control Following Hemorrhoidectomy Unknown status NCT01099605 Phase 4
19 OPTIMOX1 in Chinese mCRC Patients Unknown status NCT01023633 Phase 4 Oxaliplatin, LV, 5-FU
20 Preoperative Transhepatic Arterial Chemotherapy (TAC) in the Treatment of Liver Metastasis of Resectable Colorectal Cancer Unknown status NCT00874406 Phase 4 tac + folfox4;folfox4
21 Transhepatic Arterial Chemotherapy (TAC) Versus Transcatheter Arterial Chemoembolization (TACE) Plus Folfox4 as the Treatment of Unresectable Liver Metastasis of Colorectal Cancer Unknown status NCT00868569 Phase 4
22 Iron Therapy in Colo-Rectal Neoplasm and Iron Deficiency Anemia: Intravenous Iron Sucrose Versus Oral Ferrous Sulphate. Unknown status NCT00199277 Phase 4 i.v. iron sucrose;Oral iron
23 Preoperative Assessment of Colon Tumor Unknown status NCT00114829 Phase 4
24 Polyacrylamide Hydrogel Injection Treatment for Anal Incontinence Completed NCT02550899 Phase 4
25 NASHA/Dx as a Perianal Implant for the Treatment of Persistent Fecal Incontience After Anorectal Malformation Completed NCT03746834 Phase 4
26 Comparison of Treatment Success of Botox Injection in the Internal Sphincter Versus Isosorbidedinitrate Ointment in Patients With an Anal Fissure Completed NCT00827736 Phase 4 ISDN ointment;Placebo
27 Combined Therapy in Radiation Proctopathy Completed NCT01613534 Phase 4 Sucralfate;Placebo
28 Ability to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With Ulcerative Colitis Completed NCT01124149 Phase 4 MMX mesalamine/ mesalazine
29 Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease Completed NCT02782455 Phase 4 Flavonoids;CDobi
30 Safety and Efficacy of the Addition of Morphine Chloride to a Low Dose of Bupivacaine as Intradural Anaesthetic for the Removal Surgery of the Hemorrhoids Completed NCT02046772 Phase 4 Bupivacaine low dose;Bupivacaine standard dose;Morphine Chloride
31 A Comparative Efficacy and Safety Study of Compound Carraghenates Cream With Mayinglong Musk Hemorrhoid Ointment in the Treatment of Hemorrhoids Completed NCT01881282 Phase 4 Carraghenates Cream;Mayinglong Musk Hemorrhoid Ointment
32 Comparison Between Excisional Hemorrhoidectomy and Haemorrhoidal Dearterialisation With Anopexy Completed NCT01263431 Phase 4
33 Improvement of Pain Following Robotic Sacrocolpopexy and Rectocele Repair for Pelvic Organ Prolapse Completed NCT02449915 Phase 4 Bupivacaine;Placebo
34 Symptom Control 1-year After Circular Stapler Anopexy or Diathermy Excision for Prolapsed Haemorhoids Completed NCT00841620 Phase 4
35 Pain and Bleeding in Subjects With Acute Anal Fissure: Comparative Evaluation of Three Treatments Completed NCT03355846 Phase 4 Centella;Proctocella;Flavonil® cps;Flavonil® Cream;Rectalgan Mousse
36 Effect of Perioperative i.v. Low-dose S(+) Ketamine Completed NCT00354029 Phase 4 S (+) Ketamine;Placebo
37 What Benefit With a New Stapler Device in the Surgical Treatment of Obstructed Defecation? Completed NCT00810745 Phase 4
38 Sacral Nerve Stimulation for Anal Incontinence and Bowel Control Completed NCT00200005 Phase 4
39 Efficacy and Safety of CLIFE1 Gel in Benign Anorectal Surgery Completed NCT02961855 Phase 4 anesthesics plus antiinflammatory, CLIFE1;local anesthesics, CLIFE2
40 Discharge Conditions of Spinal Anesthesia With Heavy Prilocaine-Fentanyl and Heavy Bupivacaine-Fentanyl Completed NCT01880775 Phase 4 Prilocaine;Bupivacaine
41 Pain Relief for Thrombosed External Haemorrhoids Completed NCT00717782 Phase 4
42 RCT: STARR vs Biofeedback Completed NCT00556283 Phase 4
43 Chemotherapy Combined With CIK Treating Colon Cancer Completed NCT03084809 Phase 4 Cytokine-induced killer cells+ FOLFOX4;FOLFOX4
44 The Effects of the Proton Pump Inhibitor Esomeprazole on the Bioavailability of Regorafenib Completed NCT02800330 Phase 4 Esomeprazole 40mg concomitantly;Esomeprazole 40mg before;Regorafenib 160mg or 120mg
45 A Study of Bevacizumab (Avastin) in Combination With Chemotherapy in Participants With Metastatic Cancer of the Colon or Rectum Completed NCT02582970 Phase 4 5-Fluorouracil;Bevacizumab;Irinotecan;Oxaliplatin
46 A Study of Capecitabine (Xeloda) in the Adjuvant Treatment of Participants With Resected Colon Cancer Completed NCT02581423 Phase 4 Capecitabine
47 A Study of Capecitabine (Xeloda) in Patients With Metastatic Colorectal Cancer Completed NCT02567331 Phase 4 Capecitabine
48 Safety of Orectalip® (Oxaliplatin) as Adjuvant Treatment for High-risk Stage-Ⅱ Colorectal Cancer Completed NCT02284529 Phase 4 Orectalip
49 Intravenous Iron: Measuring Response in Anemic Surgical Patients Completed NCT02057471 Phase 4 Intravenous ferric carboxymaltose
50 Early Intervention for Erectile Dysfunction After Laparoscopic Resection for Rectal Cancer Completed NCT01912586 Phase 4

Search NIH Clinical Center for Rectal Disease

Cochrane evidence based reviews: rectal diseases

Genetic Tests for Rectal Disease

Anatomical Context for Rectal Disease

MalaCards organs/tissues related to Rectal Disease:

41
Colon, Kidney, Testes, Prostate, Liver, Spinal Cord, Cervix

Publications for Rectal Disease

Articles related to Rectal Disease:

(show all 43)
# Title Authors Year
1
Transanal Assisted Resection with Closure of Anal Canal for Lower Rectal Diseases. ( 28982899 )
2017
2
Topographic Anatomy of the Anal Sphincter Complex and Levator Ani Muscle as It Relates to Intersphincteric Resection for Very Low Rectal Disease. ( 27050605 )
2016
3
Optimizing technology for the management of colon and rectal diseases. ( 25897589 )
2015
4
Supportive therapies in ano-rectal diseases--are they really useful? ( 21066990 )
2010
5
Elastosonography in malignant rectal disease: preliminary data. ( 17427082 )
2007
6
Plasmablastic lymphoma: a case of rectal disease with spinal cord compression. ( 17169819 )
2006
7
Radiofrequency surgery--novel techniques in the treatment of ano-rectal disease. ( 17139880 )
2006
8
Incidental discovery of ano-rectal disease during transrectal ultrasound performed for prostatic disease. ( 15906788 )
2005
9
A new technique of laparoscopic surgery for rectal disease. ( 15098039 )
2004
10
EUS for rectal disease. ( 12085043 )
2002
11
Use of colostomy to manage rectal disease in dogs. ( 9232784 )
1997
12
Advances in treatment of ano-rectal diseases by the anal suppository method. ( 9389147 )
1996
13
Medical malpractice involving colon and rectal disease. ( 8287753 )
1994
14
Medical malpractice involving colon and rectal disease: a 20-year review of United States civil court litigation. ( 8500369 )
1993
15
Endoscopic ultrasonography in the evaluation of colon and rectal disease. ( 2184084 )
1990
16
Colon and rectal disease 1947-1987. ( 3313352 )
1987
17
Coloanal anastomosis in the management of benign and malignant rectal disease. ( 3675022 )
1987
18
Lord's rectal dilitation and treatment of rectal disease. ( 3998626 )
1985
19
The effects on pelvic visceral function of anal sphincter ablating and anal sphincter preserving operations for cancer of the lower part of the rectum and for benign colo-rectal disease. ( 6691700 )
1984
20
Colonoscopic retroflexion in the evaluation of rectal disease. ( 7137139 )
1982
21
The prone cross-table lateral view of the rectum: a useful projection in the evaluation of rectal disease. ( 7165608 )
1982
22
Alterations of creatine kinase isoenzymes in colon washings from patients with colonic and rectal diseases. ( 7104959 )
1982
23
Office management of colon and rectal diseases. ( 7289830 )
1981
24
Rectal disease in a patient with delirium tremens. ( 7365944 )
1980
25
Ano-rectal diseases in ancient India. ( 1091157 )
1975
26
Fiberscopic examination of colo-rectal diseases. ( 4816803 )
1974
27
The role of fiberoptic colonoscopy in the diagnosis of colonic and rectal disease. ( 4746166 )
1973
28
Investigation of colonic and rectal disease. Arteriography. ( 4642021 )
1972
29
Symposium on canine recto-anal disorders--II: The surgical pathology of ano-rectal disease in the dog. ( 5691229 )
1968
30
Evaluation of Barron ligation treatment of internal hemorrhoids and associated rectal diseases. ( 5922302 )
1966
31
Colonic and rectal disease in the young adult. ( 13975128 )
1962
32
Geriatric aspects of rectal diseases. ( 14475457 )
1961
33
Relation of ano-rectal disease to carcinoma; with special reference to hemorrhoids. ( 13340006 )
1956
34
Incidence of ano-rectal diseases; a comparison of pathologic lesions in outpatients with hospital surgical patients. ( 12996683 )
1952
35
Recent advances in the surgical treatment of colon and rectal disease. ( 18152700 )
1949
36
Ano-rectal disease; incidence in 300 males of military age with particular reference to polyposis. ( 18108281 )
1949
37
Use of oil anesthetics in rectal diseases. ( 18134171 )
1949
38
Rectal diseases. ( 18913086 )
1948
39
Treatment of patients with rectal disease. ( 20248643 )
1947
40
LOCAL ANAESTHESIA IN ANO-RECTAL DISEASE. ( 20321127 )
1938
41
Rectal Diseases-Particularly the Office Treatment of Hemorrhoids. ( 18744321 )
1937
42
Rectal Diseases-Their Injection Treatment: An Economic Problem. ( 18742786 )
1934
43
Remarks on Two Cases of Rectal Disease Treated by Modified Operative Methods. ( 20755289 )
1895

Variations for Rectal Disease

Expression for Rectal Disease

Search GEO for disease gene expression data for Rectal Disease.

Pathways for Rectal Disease

GO Terms for Rectal Disease

Cellular components related to Rectal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endolysosome membrane GO:0036020 8.96 TLR7 TLR9
2 early phagosome GO:0032009 8.62 TLR7 TLR9

Biological processes related to Rectal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of interleukin-8 production GO:0032757 9.43 TLR7 TLR9
2 positive regulation of chemokine production GO:0032722 9.4 TLR7 TLR9
3 toll-like receptor 9 signaling pathway GO:0034162 9.37 TLR7 TLR9
4 positive regulation of interferon-gamma biosynthetic process GO:0045078 9.32 TLR7 TLR9
5 I-kappaB phosphorylation GO:0007252 9.26 TLR7 TLR9
6 positive regulation of interleukin-8 biosynthetic process GO:0045416 9.16 TLR7 TLR9
7 positive regulation of interferon-beta biosynthetic process GO:0045359 8.96 TLR7 TLR9
8 positive regulation of interferon-alpha biosynthetic process GO:0045356 8.62 TLR7 TLR9

Molecular functions related to Rectal Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling pattern recognition receptor activity GO:0008329 8.96 TLR7 TLR9
2 siRNA binding GO:0035197 8.62 TLR7 TLR9

Sources for Rectal Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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