MCID: RCT008
MIFTS: 32

Rectosigmoid Junction Neoplasm

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Rectosigmoid Junction Neoplasm

MalaCards integrated aliases for Rectosigmoid Junction Neoplasm:

Name: Rectosigmoid Junction Neoplasm 12 15
Malignant Tumor of Rectosigmoid Junction 12 73
Neoplasm of Rectosigmoid Junction 12 73
Rectosigmoid Junction Cancer 12 15
Rectosigmoid Neoplasm 12 76
Rectosigmoid Cancer 12 15
Malignant Neoplasm of Rectosigmoid Junction 12
Carcinoma of the Rectosigmoid Junction 73
Malignant Neoplasm of Rectosigmoid 12
Malignant Rectosigmoid Tumor 12
Rectosigmoid Carcinoma 73
Rectosigmoid Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2780 DOID:2781 DOID:2782
ICD10 33 C19
ICD9CM 35 154.0

Summaries for Rectosigmoid Junction Neoplasm

MalaCards based summary : Rectosigmoid Junction Neoplasm, also known as malignant tumor of rectosigmoid junction, is related to secondary hypertrophic osteoarthropathy and anomalous left coronary artery from the pulmonary artery. An important gene associated with Rectosigmoid Junction Neoplasm is SMUG1 (Single-Strand-Selective Monofunctional Uracil-DNA Glycosylase 1), and among its related pathways/superpathways are Proteoglycans in cancer and Autophagy - animal. Affiliated tissues include colon, prostate and lymph node, and related phenotypes are Negative genetic interaction between PTEN-/- and PTEN+/+ and Reduced mammosphere formation

Wikipedia : 76 Colorectal cancer (CRC), also known as bowel cancer and colon cancer, is the development of cancer from... more...

Related Diseases for Rectosigmoid Junction Neoplasm

Diseases related to Rectosigmoid Junction Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
# Related Disease Score Top Affiliating Genes
1 secondary hypertrophic osteoarthropathy 10.2 KRAS SMUG1
2 anomalous left coronary artery from the pulmonary artery 10.2 KCNJ11 SMUG1
3 mature teratoma 10.1 KRAS SMUG1
4 malignant skin fibrous histiocytoma 10.1 KCNJ11 SMUG1
5 anus cancer 10.1 KRAS SMUG1
6 trachea adenoid cystic carcinoma 10.1 CTSL SMUG1
7 cecum adenocarcinoma 10.1 KRAS SMUG1
8 tracheal cancer 10.1 CTSL SMUG1
9 malignant dermis tumor 10.1 KCNJ11 SMUG1
10 kleine-levin hibernation syndrome 10.0 KCNJ11 SMUG1
11 cogan syndrome 10.0 KCNJ11 SMUG1
12 prostate cancer 10.0
13 prostatitis 10.0
14 female reproductive organ cancer 10.0 KRAS SMUG1
15 respiratory system cancer 10.0 KRAS SMUG1
16 endocrine gland cancer 9.9 KRAS SMUG1
17 peritonitis 9.9
18 cell type cancer 9.9 KRAS SMUG1
19 rectum squamous cell carcinoma 9.9 DCXR SMUG1
20 dacryocystocele 9.8 DCXR KCNJ11
21 gastrointestinal system cancer 9.8 KRAS SMUG1
22 descending colon cancer 9.8 DCXR SMUG1
23 hepatitis 9.8
24 thrombosis 9.8
25 obstructive jaundice 9.8
26 cervicitis 9.8
27 endometriosis 9.8
28 cervix endometriosis 9.8
29 fournier gangrene 9.8
30 atypical coarctation of aorta 9.8
31 factitious disorder 9.7 DCXR KCNJ11
32 chronic inflammation of lacrimal passage 9.7 DCXR KCNJ11
33 frontal sinusitis 9.6 CTSL DCXR
34 ischemia 9.5 CTSL KCNJ11
35 myeloma, multiple 9.4 KRAS SMUG1
36 rectal neoplasm 9.2 DCXR KRAS SMUG1

Comorbidity relations with Rectosigmoid Junction Neoplasm via Phenotypic Disease Network (PDN): (show all 16)


Active Peptic Ulcer Disease Acute Cystitis
Ascending Colon Cancer Cecal Benign Neoplasm
Colorectal Cancer Deficiency Anemia
Descending Colon Cancer Hepatic Flexure Cancer
Hydronephrosis Intestinal Obstruction
Intestinal Perforation Iron Deficiency Anemia
Paralytic Ileus Protein-Energy Malnutrition
Rectal Neoplasm Transverse Colon Cancer

Graphical network of the top 20 diseases related to Rectosigmoid Junction Neoplasm:



Diseases related to Rectosigmoid Junction Neoplasm

Symptoms & Phenotypes for Rectosigmoid Junction Neoplasm

GenomeRNAi Phenotypes related to Rectosigmoid Junction Neoplasm according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between PTEN-/- and PTEN+/+ GR00255-A-3 9.13 DCXR KCNJ11 SMUG1
2 Reduced mammosphere formation GR00396-S 8.92 CTSL DCXR KCNJ11 KRAS

Drugs & Therapeutics for Rectosigmoid Junction Neoplasm

Search Clinical Trials , NIH Clinical Center for Rectosigmoid Junction Neoplasm

Genetic Tests for Rectosigmoid Junction Neoplasm

Anatomical Context for Rectosigmoid Junction Neoplasm

MalaCards organs/tissues related to Rectosigmoid Junction Neoplasm:

41
Colon, Prostate, Lymph Node

Publications for Rectosigmoid Junction Neoplasm

Articles related to Rectosigmoid Junction Neoplasm:

(show top 50) (show all 62)
# Title Authors Year
1
Single-site laparoscopic colectomy for rectosigmoid cancer with middle aortic syndrome: report of a case. ( 26366350 )
2015
2
Comparison of non-schistosomal rectosigmoid cancer and schistosomal rectosigmoid cancer. ( 26109809 )
2015
3
Hartmann's procedure vs loop colostomy in the treatment of obstructive rectosigmoid cancer. ( 25324896 )
2014
4
Incidentally Detected Sigmoidovesical Fistula in a Case of Rectosigmoid Cancer Detected on FDG PET-CT. ( 24999684 )
2014
5
Unusual presentation of advanced prostate cancer masquerading as metastatic and obstructing rectosigmoid cancer. ( 25388794 )
2014
6
Pylephlebitis in patient with covered perforated rectosigmoid cancer. ( 25340866 )
2014
7
FDG PET/CT Images Demonstrating Fournier Gangrene With Bilateral Pelvic Muscle Extension in a Patient With Recurrent Rectosigmoid Cancer. ( 23510891 )
2014
8
Unusual Site of Metastasis Detected With FDG PET/CT in a Case of Recurrent Rectosigmoid Cancer. ( 24300344 )
2013
9
A first report of tumor cell implantation after EMR in a patient with rectosigmoid cancer. ( 21762905 )
2012
10
Surgical techniques of laparoscopic peritonectomy plus paraaortic lymph node dissection for the treatment of patients with positive lymph node metastasis and peritoneal seeding from rectosigmoid cancer. ( 22271336 )
2012
11
Complete Response of Isolated Para-aortic Lymph Node Recurrence from Rectosigmoid Cancer Treated by Chemoradiation Therapy with Capecitabine/Oxaliplatin plus Bevacizumab: A Case Report. ( 22679426 )
2012
12
Palliative management for patients with subacute obstruction and stage IV unresectable rectosigmoid cancer: colostomy versus endoscopic stenting: final results of a prospective randomized trial. ( 22575396 )
2012
13
Recovery of upper gastrointestinal bowel movement after rectosigmoid cancer surgery: a pilot transit analysis. ( 22808607 )
2011
14
Deep infiltrating cervical endometriosis mimicking rectosigmoid cancer. ( 21642825 )
2011
15
Rectosigmoid xanthoma as a predictive marker for sporadic rectosigmoid cancer. ( 21633307 )
2011
16
I^-Catenin and its relation to VEGF and cyclin D1 expression in pT3 rectosigmoid cancers. ( 21331989 )
2010
17
Peritoneal microdialysis. Early diagnosis of anastomotic leakage after low anterior resection for rectosigmoid cancer. ( 19919919 )
2009
18
Risk of deep vein thrombosis following laparoscopic rectosigmoid cancer resection in chinese patients. ( 18490217 )
2008
19
Preoperative irradiation and surgery for local recurrence of rectal and rectosigmoid cancer. Prognostic factors with regard to survival and further local recurrence. ( 18028472 )
2008
20
Sexual function in men with rectal and rectosigmoid cancer after laparoscopic and open surgery. ( 18795677 )
2008
21
E-cadherin, beta-catenin adhesion complex and relation to matrilysin expression in pT3 rectosigmoid cancers. ( 18674869 )
2008
22
Feasibility of laparoscopic D3 lymphadenectomy for male rectosigmoid cancer with clinically positive lymph nodes. ( 18288527 )
2008
23
Erratum: Systematic review on the short term outcome of laparoscopic resection for colon and rectosigmoid cancer. ( 18205846 )
2008
24
The depth of tumor invasion beyond the outer border of the muscularis propria as a prognostic factor for T3 rectal/rectosigmoid cancer. ( 18630458 )
2008
25
Laser Doppler assessment of the influence of division at the root of the inferior mesenteric artery on anastomotic blood flow in rectosigmoid cancer surgery. ( 17082922 )
2007
26
Economics and the laparoscopic surgery learning curve: comparison with open surgery for rectosigmoid cancer. ( 17623232 )
2007
27
Short- and midterm outcomes of laparoscopic surgery compared for 131 patients with rectal and rectosigmoid cancer. ( 17285382 )
2007
28
Laparoscopic prophylactic oophorectomy plus N3 lymphadenectomy for advanced rectosigmoid cancer. ( 17447107 )
2007
29
Re: rectosigmoid cancer after radiotherapy for prostate cancer can be detected early and successfully treated. ( 17419874 )
2007
30
Systematic review on the short-term outcome of laparoscopic resection for colon and rectosigmoid cancer. ( 16684081 )
2006
31
Comparison of long-term outcome of laparoscopic and conventional surgery for advanced colon and rectosigmoid cancer. ( 16795970 )
2006
32
Rectosigmoid cancer after radiotherapy for prostate cancer can be detected early and successfully treated. ( 16732819 )
2006
33
Radiologic assessment of rectosigmoid cancer before and after neoadjuvant radiation therapy: comparison between quantitation techniques. ( 15671374 )
2005
34
A case of rectosigmoid cancer metastasizing to a fistula in ano. ( 16275674 )
2005
35
Use of self-expanding metal stents for palliation of rectosigmoid cancer. ( 11174293 )
2001
36
Obstructive jaundice caused by lymphatic remetastasis from the hepatic metastasis of rectosigmoid cancer. ( 11702258 )
2001
37
Intraoperative radiation therapy for locally advanced recurrent rectal or rectosigmoid cancer. ( 11165686 )
2001
38
Blood dissemination of colonic epithelial cells during no-touch surgery for rectosigmoid cancer. ( 10437871 )
1999
39
The impact of 5-fluorouracil and intraoperative electron beam radiation therapy on the outcome of patients with locally advanced primary rectal and rectosigmoid cancer. ( 9712564 )
1998
40
Radiotherapy treatment for isolated loco-regional recurrence of rectosigmoid cancer following definitive surgery: Peter MacCallum Cancer Institute experience, 1981-1990. ( 9276368 )
1997
41
Application of rectal stents for palliation of obstructing rectosigmoid cancer. ( 9214327 )
1997
42
Intraoperative radiation therapy for locally advanced recurrent rectal or rectosigmoid cancer. ( 7564378 )
1995
43
Nerve-sparing surgery in 302 resectable rectosigmoid cancer patients: genitourinary morbidity and 10-year survival. ( 8313791 )
1994
44
Radiation enhancement of laser palliation for advanced rectal and rectosigmoid cancer: a pilot study. ( 7688336 )
1993
45
Combined treatment of pelvic exenterative surgery and intra-operative pelvic hyperthermochemotherapy for locally advanced rectosigmoid cancer: report of a case. ( 8118126 )
1993
46
Postoperative radiotherapy for rectal and rectosigmoid cancer: the impact of total dose on local control. ( 1470697 )
1992
47
Radioimmunolocalization of pelvic recurrences from rectosigmoid cancer employing 111In anti-CEA F(ab')2. ( 2010306 )
1991
48
Endoscopic Nd:YAG laser treatment of rectosigmoid cancer. ( 1695161 )
1990
49
Local recurrence of rectosigmoid cancer: what about the choice of MRI for diagnosis? ( 2210210 )
1990
50
Preoperative prediction of outcome in patients with rectal and rectosigmoid cancer. ( 2702591 )
1989

Variations for Rectosigmoid Junction Neoplasm

Expression for Rectosigmoid Junction Neoplasm

Search GEO for disease gene expression data for Rectosigmoid Junction Neoplasm.

Pathways for Rectosigmoid Junction Neoplasm

Pathways related to Rectosigmoid Junction Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.26 CTSL KRAS
2 10.73 CTSL KRAS

GO Terms for Rectosigmoid Junction Neoplasm

Biological processes related to Rectosigmoid Junction Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 glucose metabolic process GO:0006006 8.62 DCXR KCNJ11

Sources for Rectosigmoid Junction Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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