MCID: RCT020
MIFTS: 40

Rectum Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Rectum Adenocarcinoma

MalaCards integrated aliases for Rectum Adenocarcinoma:

Name: Rectum Adenocarcinoma 12 15
Rectal Adenocarcinoma 12 6 17
Adenocarcinoma of Rectum 74

Classifications:



External Ids:

Disease Ontology 12 DOID:1996
NCIt 51 C9383
UMLS 74 C0149978

Summaries for Rectum Adenocarcinoma

Disease Ontology : 12 A rectum cancer that derives from epithelial cells of glandular origin.

MalaCards based summary : Rectum Adenocarcinoma, also known as rectal adenocarcinoma, is related to mammary paget's disease and anal canal adenocarcinoma. An important gene associated with Rectum Adenocarcinoma is RAB11B (RAB11B, Member RAS Oncogene Family), and among its related pathways/superpathways is Cytoskeletal Signaling. The drugs leucovorin and Capecitabine have been mentioned in the context of this disorder. Affiliated tissues include colon, testes and lymph node.

Related Diseases for Rectum Adenocarcinoma

Diseases related to Rectum Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 192)
# Related Disease Score Top Affiliating Genes
1 mammary paget's disease 30.4 KRT20 KRT7
2 anal canal adenocarcinoma 30.4 CDX2 KRT7
3 cystadenoma 30.2 KRT20 KRT7
4 gastric adenocarcinoma 29.4 CDX2 CEACAM5 KRT20 KRT7
5 rectum mucinous adenocarcinoma 11.2
6 adenocarcinoma 10.5
7 cecal benign neoplasm 10.4 KRT7 RAB11B
8 ovary neuroendocrine neoplasm 10.4 CDX2 KRT7
9 duodenum adenocarcinoma 10.4 CDX2 KRT7
10 epithelial predominant wilms' tumor 10.4 CDX2 KRT7
11 colon adenocarcinoma 10.4
12 nasal cavity cancer 10.4 CDX2 KRT7
13 nasal cavity adenocarcinoma 10.4 CDX2 KRT7
14 cystic basal cell carcinoma 10.3 KRT20 KRT7
15 seminal vesicle adenocarcinoma 10.3 KRT20 KRT7
16 transverse colon cancer 10.3 KRT20 KRT7
17 malignant syringoma 10.3 KRT20 KRT7
18 papillary transitional carcinoma 10.3 KRT20 KRT7
19 eyelid carcinoma 10.3 KRT20 KRT7
20 krukenberg carcinoma 10.3 KRT20 KRT7
21 large intestine adenocarcinoma 10.3 KRT20 KRT7
22 linitis plastica 10.3 KRT20 KRT7
23 lung acinar adenocarcinoma 10.3 KRT20 KRT7
24 small cell carcinoma of the bladder 10.3 KRT20 KRT7
25 adenoid squamous cell carcinoma 10.3 KRT20 KRT7
26 intratubular embryonal carcinoma 10.3 KRT20 KRT7
27 bile duct adenoma 10.3 KRT20 KRT7
28 vaginal benign neoplasm 10.3 CDX2 KRT20
29 vaginal adenoma 10.3 CDX2 KRT20
30 vaginal tubulovillous adenoma 10.3 CDX2 KRT20
31 villous adenoma 10.3 CDX2 KRT20
32 bladder lymphoma 10.3 KRT20 KRT7
33 papillary serous adenocarcinoma 10.3 KRT20 KRT7
34 hypotrichosis 3 10.3 RAB11B RAB1A
35 medulloepithelioma 10.3 KRT20 KRT7
36 glycogen-rich clear cell breast carcinoma 10.3 KRT20 KRT7
37 duodenum cancer 10.3 CDX2 KRT7
38 renal pelvis carcinoma 10.3 KRT20 KRT7
39 paget disease, extramammary 10.3 KRT20 KRT7
40 cutaneous mucoepidermoid carcinoma 10.3 CEACAM5 KRT7
41 anal gland adenocarcinoma 10.3 CEACAM5 KRT7
42 hidradenocarcinoma 10.3 CDX2 KRT7
43 malignant spiradenoma 10.3 CEACAM5 KRT7
44 lymphoepithelioma-like carcinoma 10.3 KRT20 KRT7
45 eccrine sweat gland neoplasm 10.3 KRT20 KRT7
46 bile duct mucoepidermoid carcinoma 10.3 CEACAM5 KRT7
47 dermoid cyst 10.3 KRT20 KRT7
48 cutaneous adenocystic carcinoma 10.3 CEACAM5 KRT7
49 gastric tubular adenocarcinoma 10.3 CDX2 KRT7
50 cystadenofibroma 10.3 KRT20 KRT7

Graphical network of the top 20 diseases related to Rectum Adenocarcinoma:



Diseases related to Rectum Adenocarcinoma

Symptoms & Phenotypes for Rectum Adenocarcinoma

Drugs & Therapeutics for Rectum Adenocarcinoma

Drugs for Rectum Adenocarcinoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 250)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
leucovorin Approved Phase 3,Phase 2,Phase 1,Not Applicable 58-05-9 143 6006
2
Capecitabine Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 154361-50-9 60953
3
Oxaliplatin Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 61825-94-3 43805 6857599 5310940 9887054
4
Fluorouracil Approved Phase 3,Phase 2,Phase 1,Not Applicable 51-21-8 3385
5
Levoleucovorin Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 68538-85-2
6
Cobalt Approved, Experimental Phase 3 7440-48-4 104729
7
Cetuximab Approved Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 205923-56-4 56842117 2333
8
Irinotecan Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 100286-90-6, 97682-44-5 60838
9
Panitumumab Approved, Investigational Phase 3,Phase 2 339177-26-3 50070211
10
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2 22916-47-8 4189
11
Bevacizumab Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 216974-75-3
12
Raltitrexed Approved, Investigational Phase 3,Phase 2 112887-68-0 104758
13
Celecoxib Approved, Investigational Phase 3,Phase 2,Phase 1,Not Applicable 169590-42-5 2662
14
lanreotide Approved Phase 3 108736-35-2
15
Tegafur Approved, Investigational Phase 3,Phase 2 17902-23-7 5386
16
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 3 7487-88-9 24083
17
Doxorubicin Approved, Investigational Phase 3,Phase 2 23214-92-8 31703
18
Cisplatin Approved Phase 3,Phase 2 15663-27-1 2767 441203 84093
19
Floxuridine Approved Phase 3,Phase 2,Phase 1 50-91-9 5790
20
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 1177-87-3
21
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 50-02-2 5743
22
Histamine Approved, Investigational Phase 3,Phase 2 51-45-6 774
23
Trioxsalen Approved Phase 2, Phase 3 3902-71-4 5585
24
Diphenhydramine Approved, Investigational Phase 3 147-24-0, 58-73-1 3100
25
Promethazine Approved, Investigational Phase 3 60-87-7 4927
26
Calcium Approved, Nutraceutical Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1 7440-70-2 271
27
Folic Acid Approved, Nutraceutical, Vet_approved Phase 3,Phase 2,Phase 1 59-30-3 6037
28
Eniluracil Investigational Phase 3 59989-18-3
29
Camptothecin Experimental Phase 3,Phase 2,Phase 1 7689-03-4
30
Doxil Approved June 1999 Phase 3,Phase 2 31703
31 Edrecolomab Experimental, Investigational Phase 3 156586-89-9
32 Antimetabolites, Antineoplastic Phase 3,Phase 2,Phase 1,Not Applicable
33 Antimetabolites Phase 3,Phase 2,Phase 1,Not Applicable
34 Calcium, Dietary Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
35 Immunosuppressive Agents Phase 3,Phase 2,Phase 1,Not Applicable
36 Antidotes Phase 3,Phase 2,Phase 1,Not Applicable
37 Immunologic Factors Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
38 Protective Agents Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
39 Cola Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
40 Antineoplastic Agents, Immunological Phase 3,Phase 2,Phase 1,Not Applicable,Early Phase 1
41 Anesthetics Phase 3
42 Topoisomerase Inhibitors Phase 3,Phase 2,Phase 1
43 topoisomerase I inhibitors Phase 3,Phase 2,Phase 1
44 Antirheumatic Agents Phase 3,Phase 2,Phase 1,Not Applicable
45 Dermatologic Agents Phase 3,Phase 2
46 Antifungal Agents Phase 3,Phase 2
47 Calcineurin Inhibitors Phase 3,Phase 2
48 Cyclosporins Phase 3,Phase 2
49 Anti-Infective Agents Phase 3,Phase 1,Phase 2
50 Angiogenesis Inhibitors Phase 3,Phase 2,Phase 1,Not Applicable

Interventional clinical trials:

(show top 50) (show all 390)
# Name Status NCT ID Phase Drugs
1 A Study Comparing Adjuvant Chemotherapy Versus Observation for Patients With Rectal Adenocarcinoma After Neoadjuvant Chemo-Radiotherapy Treatment. Unknown status NCT01941979 Phase 3 5-FU, Capecitabine, Oxaliplatin, Leucovorin.
2 J-Pouch Coloanal Anastomosis Compared With Side-to-End Coloanal Anastomosis After Radiation Therapy and Surgery to Remove the Rectum in Treating Patients With Rectal Adenocarcinoma Unknown status NCT00070005 Phase 3
3 Resource-Sparing Curative Treatment for Rectal Cancer Unknown status NCT01459328 Phase 3
4 Radiation Therapy and Capecitabine With or Without Oxaliplatin in Treating Patients Who Are Undergoing Surgery for Stage II or Stage III Rectal Cancer Unknown status NCT00227747 Phase 3 capecitabine;oxaliplatin
5 Radiation Therapy Plus Chemotherapy Before Surgery With or Without Chemotherapy After Surgery in Treating Patients With Rectal Cancer Unknown status NCT00002896 Phase 3 chemotherapy;fluorouracil;leucovorin calcium
6 Laparoscopic Anterior Resection With or Without "Dog Ear" Double-stapled Anastomosis for Rectal Cancer Unknown status NCT02770911 Phase 3
7 Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Total Mesorectal Excision in T2-T3s N0, M0 Rectal Cancer Unknown status NCT01308190 Phase 3 Capecitabine (Xeloda)
8 COLOR II: Laparoscopic Versus Open Rectal Cancer Removal Unknown status NCT00297791 Phase 3
9 Radiation Therapy and Either Capecitabine or Fluorouracil With or Without Oxaliplatin Before Surgery in Treating Patients With Resectable Rectal Cancer Unknown status NCT00058474 Phase 3 capecitabine;fluorouracil;oxaliplatin
10 Combination Chemotherapy With or Without Cetuximab as First-Line Therapy in Treating Patients With Metastatic Colorectal Cancer Unknown status NCT00182715 Phase 3 capecitabine;fluorouracil;leucovorin calcium;oxaliplatin
11 A Randomized Controlled Clinical Trial Comparing Oncological Results and Functional Recovery Between Laparoscopic and Open Method for the Treatment of Advanced Rectal Cancer After Concurrent Chemoradiation Therapy (CCRT) Unknown status NCT00601549 Phase 3
12 Leucovorin and Fluorouracil With or Without Oxaliplatin Compared to Capecitabine With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer Unknown status NCT00070213 Phase 3 FOLFOX regimen;capecitabine;fluorouracil;leucovorin calcium;oxaliplatin
13 Irinotecan With or Without Panitumumab or Cyclosporine in Treating Patients With Advanced or Metastatic Colorectal Cancer That Did Not Respond to Fluorouracil Unknown status NCT00389870 Phase 3 cyclosporine;irinotecan hydrochloride
14 Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery Unknown status NCT00274872 Phase 2, Phase 3 fluorouracil;leucovorin calcium;oxaliplatin
15 Combination Chemotherapy in Treating Patients With Recurrent Metastatic Colorectal Cancer Unknown status NCT00003260 Phase 3 FOLFIRI regimen;FOLFOX regimen;fluorouracil;irinotecan hydrochloride;leucovorin calcium;oxaliplatin
16 Combination Chemotherapy With or Without SU5416 in Treating Patients With Metastatic Colorectal Cancer Unknown status NCT00021281 Phase 3 FOLFIRI regimen;fluorouracil;irinotecan hydrochloride;leucovorin calcium;semaxanib
17 Comparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer Unknown status NCT00008281 Phase 3 FOLFOX regimen;fluorouracil;leucovorin calcium;oxaliplatin
18 Comparing Two Combination Chemotherapy Regimens in Treating Patients With Metastatic Colorectal Cancer Unknown status NCT00006468 Phase 3 FOLFOX regimen;fluorouracil;leucovorin calcium;oxaliplatin
19 Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer Unknown status NCT00482222 Phase 3 capecitabine;fluorouracil;leucovorin calcium;oxaliplatin
20 Cetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal Cancer Unknown status NCT00265850 Phase 3 FOLFOX or;FOLFIRI
21 Intravenous Compared With Intrahepatic Chemotherapy in Treating Patients With Colorectal Cancer Metastatic to the Liver Unknown status NCT00002692 Phase 3 fluorouracil;isolated perfusion;leucovorin calcium
22 Palliative Chemotherapy in Treating Patients With Advanced Colorectal Cancer Unknown status NCT00002893 Phase 3 fluorouracil;leucovorin calcium;raltitrexed
23 A Randomised Trial of Preoperative Radiotherapy for Stage T3 Adenocarcinoma of Rectum Completed NCT00145769 Phase 3 Short Course Adjuvent Chemotherapy;Long Course Adjuvant Chemotherapy;Concurrent Chemotherapy
24 GRECCAR 8: Primary Tumor Resection in Rectal Cancer With Unresectable Metastasis Completed NCT02314182 Phase 3 Oxaliplatin/irinotecan + capecitabine, 5-FUI ± bevacizumab
25 Influence of Somatuline Autogel 120mg on Post-operative Drainage After Total Mesorectum Excision for Rectumcarcinoma Completed NCT01372007 Phase 3 Lanreotide Autogel 120mg;Placebo
26 Sphincter-preserving Surgery After Preoperative Treatment of Ultra-low Rectal Carcinoma Completed NCT00979680 Phase 3
27 Laparoscopic Assisted Versus Open Resection for Colorectal Carcinoma Completed NCT00485316 Phase 3
28 Neoadjuvant Radiotherapy Followed by Transanal Endoscopic Microsurgery for T1-T2 Extraperitoneal Rectal Cancer Completed NCT02127645 Phase 3
29 Capecitabine and Oxaliplatin or Standard Follow-Up Care in Treating Patients Who Have Undergone Surgery for Locally Advanced Rectal Cancer Completed NCT00427713 Phase 3 capecitabine;oxaliplatin
30 Chemotherapy and Radiation Therapy Before Surgery Followed by Capecitabine With or Without Oxaliplatin in Treating Patients With Locally Advanced Rectal Cancer Completed NCT00766155 Phase 3 capecitabine;oxaliplatin
31 Radiation Therapy With or Without Chemotherapy Before Surgery in Treating Patients With Stage II or Stage III Rectal Cancer Completed NCT00296608 Phase 3 fluorouracil;leucovorin calcium
32 SWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically Removed Completed NCT00002551 Phase 3 fluorouracil;leucovorin calcium;levamisole hydrochloride
33 Radiation Therapy, Surgery, and Chemotherapy in Treating Patients With Rectal Cancer That Can Be Surgically Removed Completed NCT00002523 Phase 3 fluorouracil;leucovorin calcium
34 Combination Chemotherapy With or Without Celecoxib in Treating Patients With Metastatic Colorectal Cancer Completed NCT00064181 Phase 3 FOLFIRI regimen;capecitabine;celecoxib;fluorouracil;irinotecan hydrochloride;leucovorin calcium
35 Tegafur-Uracil or Observation in Treating Patients With Stage II Colorectal Cancer That Has Been Completely Removed By Surgery Completed NCT00392899 Phase 3 UFT adjuvant chemotherapy
36 Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients Following Surgery for Stage III Colorectal Cancer Completed NCT00026273 Phase 3 FOLFIRI regimen;fluorouracil;irinotecan hydrochloride;leucovorin calcium
37 Radiation Therapy Before Surgery Compared With Chemotherapy Plus Radiation After Surgery in Treating Patients With Rectal Cancer That Can Be Surgically Removed Completed NCT00003422 Phase 3 fluorouracil;leucovorin calcium
38 Irinotecan Compared With Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer Completed NCT00005036 Phase 3 irinotecan hydrochloride;oxaliplatin;leucovorin calcium;fluorouracil
39 Fluorouracil With or Without Eniluracil in Treating Patients With Advanced Colorectal Cancer Completed NCT00003873 Phase 3 fluorouracil;eniluracil
40 Combination Chemotherapy in Treating Patients With Colorectal Cancer and Resectable Metastases Completed NCT00268398 Phase 3 oxaliplatin, folinic acid, fluorouracil;oxaliplatin, irinotecan, folinic acid, fluorouracil
41 Optimized Chemotherapy Followed by Maintenance With Bevacizumab With or Without Erlotinib in Treating Patients With Metastatic Colorectal Cancer That Cannot be Removed by Surgery (DREAM) Completed NCT00265824 Phase 3 bevacizumab;bevacizumab, erlotinib
42 Combination Chemotherapy With or Without Bevacizumab Compared With Bevacizumab Alone in Treating Patients With Advanced or Metastatic Colorectal Cancer That Has Been Previously Treated Completed NCT00025337 Phase 3 oxaliplatin;leucovorin calcium;fluorouracil
43 Comparison of Adjuvant Chemotherapy Regimens in Treating Stage II/III Rectal Cancer Completed NCT00068692 Phase 3 Fluorouracil;Leucovorin Calcium;Oxaliplatin;Irinotecan
44 Combination Chemotherapy as First-Line Therapy in Treating Older Patients With Metastatic Colorectal Cancer That Cannot Be Removed By Surgery Completed NCT00303771 Phase 3 fluorouracil;irinotecan hydrochloride;leucovorin calcium
45 Oxaliplatin and Bevacizumab (Avastin™) With Either Fluorouracil and Leucovorin or Capecitabine in Treating Patients With Advanced Colorectal Cancer Completed NCT00062426 Phase 3 capecitabine;fluorouracil;leucovorin calcium;oxaliplatin
46 Fluorouracil and Leucovorin With or Without Irinotecan in Treating Patients With Metastatic Colorectal Cancer Completed NCT00004885 Phase 3 FOLFIRI regimen;fluorouracil;irinotecan hydrochloride;leucovorin calcium
47 Combination Chemotherapy in Treating Patients With Recurrent or Metastatic Colorectal Cancer Completed NCT00003287 Phase 3 FOLFOX regimen;fluorouracil;leucovorin calcium;oxaliplatin
48 Combination Chemotherapy in Treating Patients With Unresectable Metastatic Colorectal Cancer Completed NCT00008060 Phase 3 FOLFIRI regimen;FOLFOX regimen;fluorouracil;irinotecan hydrochloride;leucovorin calcium;oxaliplatin
49 Rectal Reconstruction in Treating Patients Who Are Undergoing Surgery for Rectal Cancer Completed NCT00238381 Phase 3
50 Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer Completed NCT00975897 Phase 2, Phase 3 fluorouracil;irinotecan hydrochloride;leucovorin calcium;oxaliplatin

Search NIH Clinical Center for Rectum Adenocarcinoma

Genetic Tests for Rectum Adenocarcinoma

Anatomical Context for Rectum Adenocarcinoma

MalaCards organs/tissues related to Rectum Adenocarcinoma:

42
Colon, Testes, Lymph Node, Prostate, Thyroid, Appendix, Bone

Publications for Rectum Adenocarcinoma

Articles related to Rectum Adenocarcinoma:

(show top 50) (show all 542)
# Title Authors Year
1
Transanal endolaparoscopic t2n0m0 low rectal adenocarcinoma resection followed by adjuvant therapy. ( 31055878 )
2019
2
EUS versus Magnetic Resonance Imaging in Staging Rectal Adenocarcinoma: A Diagnostic Test Accuracy Meta-Analysis. ( 31004599 )
2019
3
Rectal adenocarcinoma with rectoprostatic fistula following prostate brachytherapy. ( 30936326 )
2019
4
Survival Outcomes After Surgical Management of the Primary Tumor With and Without Radiotherapy for Metastatic Rectal Adenocarcinoma: A National Cancer Database (NCDB) Analysis. ( 30905549 )
2019
5
Radiogenomics of rectal adenocarcinoma in the era of precision medicine: A pilot study of associations between qualitative and quantitative MRI imaging features and genetic mutations. ( 30927944 )
2019
6
Thymidylate synthase gene polymorphism predicts disease free survival in stage II-III rectal adenocarcinoma patients receiving adjuvant 5-FU-based chemotherapy. ( 30823845 )
2019
7
Oncologic outcomes for low rectal adenocarcinoma following low anterior resection with coloanal anastomosis versus abdominoperineal resection: a National Cancer Database propensity matched analysis. ( 30790033 )
2019
8
Refining the Use of Adjuvant Oxaliplatin in Clinical Stage II or III Rectal Adenocarcinoma. ( 30696723 )
2019
9
Surgeon-Level Variation in Utilization of Local Staging and Neoadjuvant Therapy for Stage II-III Rectal Adenocarcinoma. ( 30706375 )
2019
10
Rectal adenocarcinoma presenting with thigh muscle metastasis as the only metastatic site. ( 30674489 )
2019
11
Rectal adenocarcinoma: rare metastasis to the optic nerve. ( 30679231 )
2019
12
Diffusion kurtosis imaging-derived histogram metrics for prediction of KRAS mutation in rectal adenocarcinoma: Preliminary findings. ( 30637861 )
2019
13
Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells. ( 30637920 )
2019
14
Facility Variation in Local Staging of Rectal Adenocarcinoma and its Contribution to Underutilization of Neoadjuvant Therapy. ( 30421120 )
2019
15
Minimally Invasive Surgery for Rectal Adenocarcinoma Shows Promising Outcomes Compared to Laparotomy, a National Cancer Database Observational Analysis. ( 30431390 )
2019
16
Factors associated with noncomplete mesorectal excision following surgery for rectal adenocarcinoma. ( 30454839 )
2019
17
Preoperative localization through a harpoon of local recurrence of rectal adenocarcinoma after abdominoperineal amputation. ( 30078443 )
2019
18
Is transanal excision safe for a T1 rectal adenocarcinoma? ( 30600603 )
2019
19
Quantitative MRI assessment of mucinous rectal adenocarcinoma to predict tumour response after neoadjuvant therapy. ( 30686505 )
2019
20
The Role of Adjuvant Chemotherapy in ypT0N0 Rectal Adenocarcinoma. ( 30729373 )
2019
21
Treatment of Inguinal Lymph Node Metastases in Patients with Rectal Adenocarcinoma. ( 30725310 )
2019
22
Locally advanced rectal adenocarcinoma: Are preoperative short and long course radiotherapy truly equivalent? ( 30967950 )
2019
23
Metaplastic rectal adenocarcinoma into metastatic mucinous carcinoma on the buttock: The efficacy of immunohistochemistry. ( 30932233 )
2019
24
Phenytoin Toxicity During Neoadjuvant Concurrent Capecitabine and Radiation Therapy for Rectal Adenocarcinoma: Case Report of a Drug Interaction. ( 30697501 )
2018
25
TTF1 Expression in Pulmonary Metastatic Rectal Adenocarcinoma. ( 30631609 )
2018
26
Planned organ preservation for early T2-3 rectal adenocarcinoma: A French, multicentre study. ( 30580125 )
2018
27
Comment on: Closure of the perineal defect after abdominoperineal excision for rectal adenocarcinoma - ACPGBI Position Statement. ( 30586221 )
2018
28
Esophagitis dissecans superficialis as the first manifestation of rectal adenocarcinoma. ( 30543198 )
2018
29
The Relationship between Mesorectal Grading and Oncologic Outcomes in Rectal Adenocarcinoma. ( 30565830 )
2018
30
Interpreting the Long-term Prognostic Value of Total Mesorectal Excision Plane Quality in Rectal Adenocarcinoma. ( 30427976 )
2018
31
Predictive Value of Leukocyte- and Platelet-Derived Ratios in Rectal Adenocarcinoma. ( 30463730 )
2018
32
Treatment of primary rectal adenocarcinoma after prior pelvic radiation: The role of hyperfractionated accelerated reirradiation. ( 30370360 )
2018
33
Utilization of short-course radiation therapy for patients with nonmetastatic rectal adenocarcinoma in the United States. ( 30370362 )
2018
34
Impact of histological subtype on treatment outcomes in locally advanced rectal adenocarcinoma treated with neoadjuvant chemoradiation. ( 30264625 )
2018
35
Closure of the perineal defect after abdominoperineal excision for rectal adenocarcinoma - ACPGBI Position Statement. ( 30182511 )
2018
36
Thyroid metastasis from rectal adenocarcinoma. ( 30108119 )
2018
37
A Multicenter Matched Comparison of Transanal and Robotic Total Mesorectal Excision for Mid and Low-rectal Adenocarcinoma. ( 29916871 )
2018
38
Uterine Corpus Metastasis From Rectal Adenocarcinoma Detected Using 18F-FDG PET/CT. ( 29916919 )
2018
39
Prognostic accuracy of different lymph node staging systems in rectal adenocarcinoma with or without preoperative radiation therapy. ( 29788392 )
2018
40
Oncological outcomes in extended time intervals betweenpreoperative chemoradiotherapy with capecitabine and surgery inoperable rectal adenocarcinoma. ( 29791416 )
2018
41
Prospective Trial on Probe-Based Confocal Laser Endomicroscopy for the Identification of the Distal Limit in Rectal Adenocarcinoma. ( 29732957 )
2018
42
Rectal neuroendocrine tumor as an incidental finding in the doughnut of rectal adenocarcinoma resection specimen. What would have happened if we had not examined the doughnut? ( 29169613 )
2018
43
Paraneoplastic Pyoderma Gangrenosum Associated with Rectal Adenocarcinoma. ( 29386837 )
2018
44
Whole-tumour diffusion kurtosis MR imaging histogram analysis of rectal adenocarcinoma: Correlation with clinical pathologic prognostic factors. ( 29063250 )
2018
45
The Impact of Surgical Timing on Pathologic Tumor Response after Short Course and Long Course Preoperative Chemoradiation for Locally Advanced Rectal Adenocarcinoma. ( 29161802 )
2018
46
Does Delaying Surgical Resection After Neoadjuvant Chemoradiation Impact Clinical Outcomes in Locally Advanced Rectal Adenocarcinoma?: A Single-Institution Experience. ( 26535992 )
2018
47
Assessment of the inferior mesenteric vein diameter as a surrogate marker to evaluate response to neoadjuvant chemoradiotherapy for locally advanced rectal adenocarcinoma. ( 29027358 )
2018
48
miR-194 as predictive biomarker of responsiveness to neoadjuvant chemoradiotherapy in patients with locally advanced rectal adenocarcinoma. ( 28870889 )
2018
49
A Phase I Clinical Trial of the Phosphatidylserine-targeting Antibody Bavituximab in Combination With Radiation Therapy and Capecitabine in the Preoperative Treatment of Rectal Adenocarcinoma. ( 28763330 )
2018
50
"Miner's cap-like" solitary frontal bone metastasis from rectal adenocarcinoma on 18F-FDG PET/CT. ( 28728779 )
2018

Variations for Rectum Adenocarcinoma

ClinVar genetic disease variations for Rectum Adenocarcinoma:

6
# Gene Variation Type Significance SNP ID Assembly Location
1 APC NM_000038.5(APC): c.811A> G (p.Met271Val) single nucleotide variant Uncertain significance rs587781464 GRCh37 Chromosome 5, 112137057: 112137057
2 APC NM_000038.5(APC): c.811A> G (p.Met271Val) single nucleotide variant Uncertain significance rs587781464 GRCh38 Chromosome 5, 112801360: 112801360
3 APC NM_000038.5(APC): c.1984C> A (p.Leu662Ile) single nucleotide variant Uncertain significance rs756859993 GRCh37 Chromosome 5, 112173275: 112173275
4 APC NM_000038.5(APC): c.1984C> A (p.Leu662Ile) single nucleotide variant Uncertain significance rs756859993 GRCh38 Chromosome 5, 112837578: 112837578
5 APC NM_000038.5(APC): c.6152A> G (p.Lys2051Arg) single nucleotide variant Uncertain significance rs1554087256 GRCh37 Chromosome 5, 112177443: 112177443
6 APC NM_000038.5(APC): c.6152A> G (p.Lys2051Arg) single nucleotide variant Uncertain significance rs1554087256 GRCh38 Chromosome 5, 112841746: 112841746
7 APC NM_001127510.2(APC): c.3160C> T (p.His1054Tyr) single nucleotide variant Uncertain significance rs1195583636 GRCh37 Chromosome 5, 112174451: 112174451
8 APC NM_001127510.2(APC): c.3160C> T (p.His1054Tyr) single nucleotide variant Uncertain significance rs1195583636 GRCh38 Chromosome 5, 112838754: 112838754

Expression for Rectum Adenocarcinoma

Search GEO for disease gene expression data for Rectum Adenocarcinoma.

Pathways for Rectum Adenocarcinoma

Pathways related to Rectum Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.41 KRT20 KRT7 RAB11B RAB1A

GO Terms for Rectum Adenocarcinoma

Biological processes related to Rectum Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 melanosome transport GO:0032402 8.62 RAB11B RAB1A

Sources for Rectum Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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