MCID: RCT035
MIFTS: 17

Rectum Adenoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Rectum Adenoma

MalaCards integrated aliases for Rectum Adenoma:

Name: Rectum Adenoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050915

Summaries for Rectum Adenoma

Disease Ontology : 12 An rectal neoplasm that has material basis in epithelial tissue with glandular origin.

MalaCards based summary : Rectum Adenoma is related to adenoma and peutz-jeghers syndrome. An important gene associated with Rectum Adenoma is JTB (Jumping Translocation Breakpoint). The drug Cola has been mentioned in the context of this disorder. Affiliated tissues include colon, and related phenotypes are Nuclear 60S biogenesis defects and Nucleoplasmic pre-40S maturation defects

Related Diseases for Rectum Adenoma

Diseases related to Rectum Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adenoma 10.4
2 peutz-jeghers syndrome 9.9
3 diarrhea 9.9
4 in situ carcinoma 9.9

Symptoms & Phenotypes for Rectum Adenoma

GenomeRNAi Phenotypes related to Rectum Adenoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Nuclear 60S biogenesis defects GR00209-A-3 8.96 RPL19 RPL27A
2 Nucleoplasmic pre-40S maturation defects GR00209-A-1 8.62 RPL19 RPL27A

MGI Mouse Phenotypes related to Rectum Adenoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 8.92 JTB MYC RPL27A S100A10

Drugs & Therapeutics for Rectum Adenoma

Drugs for Rectum Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Cola

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Colorectal Cancer Screening in Norway: Pilot Study of a National Screening Programme With Randomised Comparison of Different Screening Strategies to Provide the Best Possible Service to the Population Active, not recruiting NCT01538550

Search NIH Clinical Center for Rectum Adenoma

Genetic Tests for Rectum Adenoma

Anatomical Context for Rectum Adenoma

MalaCards organs/tissues related to Rectum Adenoma:

40
Colon

Publications for Rectum Adenoma

Articles related to Rectum Adenoma:

# Title Authors PMID Year
1
Metformin use and the risk of colorectal adenoma: A systematic review and meta-analysis. 61
28449338 2017
2
Endoscopic mucosal resection of flat and sessile colorectal adenomas: our experience with long-term follow-ups. 61
24516988 2014
3
Meat, meat cooking methods and preservation, and risk for colorectal adenoma. 61
16140978 2005
4
[Treatment of rectum adenoma. Retrospective study of the treatment of inpatients (1987-1991)]. 61
8701268 1996
5
[Differential diagnosis at the bedside - villous rectum adenoma. Main symptom "diarrhea"]. 61
6796881 1981
6
[Pathology and classification of colorectal polyps]. 61
451434 1979
7
[Elektrolyte-losing rectum adenoma (author's transl)]. 61
636701 1978
8
Malignant adenomas of the colon and rectum; (adenoma malignum). 61
14891072 1951

Variations for Rectum Adenoma

Expression for Rectum Adenoma

Search GEO for disease gene expression data for Rectum Adenoma.

Pathways for Rectum Adenoma

GO Terms for Rectum Adenoma

Cellular components related to Rectum Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ribosome GO:0005840 8.96 RPL27A RPL19
2 cytosolic large ribosomal subunit GO:0022625 8.62 RPL27A RPL19

Biological processes related to Rectum Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 translational initiation GO:0006413 9.26 RPL27A RPL19
2 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 9.16 RPL27A RPL19
3 viral transcription GO:0019083 8.96 RPL27A RPL19
4 SRP-dependent cotranslational protein targeting to membrane GO:0006614 8.62 RPL27A RPL19

Molecular functions related to Rectum Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of ribosome GO:0003735 8.62 RPL27A RPL19

Sources for Rectum Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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