MCID: RCT035
MIFTS: 20

Rectum Adenoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Rectum Adenoma

MalaCards integrated aliases for Rectum Adenoma:

Name: Rectum Adenoma 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050915

Summaries for Rectum Adenoma

Disease Ontology : 12 An rectal neoplasm that has material basis in epithelial tissue with glandular origin.

MalaCards based summary : Rectum Adenoma is related to adenoma and diarrhea. An important gene associated with Rectum Adenoma is RPL27A (Ribosomal Protein L27a), and among its related pathways/superpathways are HIV Life Cycle and Colorectal Cancer Metastasis. Affiliated tissues include colon, and related phenotypes are Nuclear 60S biogenesis defects and integument

Related Diseases for Rectum Adenoma

Diseases related to Rectum Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adenoma 10.2
2 diarrhea 9.9
3 sezary's disease 9.6 TGFBR2 MYC
4 diamond-blackfan anemia 9.4 RPL27A RPL19 MYC

Symptoms & Phenotypes for Rectum Adenoma

GenomeRNAi Phenotypes related to Rectum Adenoma according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Nuclear 60S biogenesis defects GR00209-A-3 8.62 RPL19 RPL27A

MGI Mouse Phenotypes related to Rectum Adenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 integument MP:0010771 9.26 MYC RPL27A S100A10 TGFBR2
2 pigmentation MP:0001186 8.8 MYC RPL27A TGFBR2

Drugs & Therapeutics for Rectum Adenoma

Search Clinical Trials , NIH Clinical Center for Rectum Adenoma

Genetic Tests for Rectum Adenoma

Anatomical Context for Rectum Adenoma

MalaCards organs/tissues related to Rectum Adenoma:

40
Colon

Publications for Rectum Adenoma

Articles related to Rectum Adenoma:

# Title Authors PMID Year
1
Metformin use and the risk of colorectal adenoma: A systematic review and meta-analysis. 61
28449338 2017
2
Endoscopic mucosal resection of flat and sessile colorectal adenomas: our experience with long-term follow-ups. 61
24516988 2014
3
Meat, meat cooking methods and preservation, and risk for colorectal adenoma. 61
16140978 2005
4
[Treatment of rectum adenoma. Retrospective study of the treatment of inpatients (1987-1991)]. 61
8701268 1996
5
[Differential diagnosis at the bedside - villous rectum adenoma. Main symptom "diarrhea"]. 61
6796881 1981
6
[Pathology and classification of colorectal polyps]. 61
451434 1979
7
[Elektrolyte-losing rectum adenoma (author's transl)]. 61
636701 1978
8
Malignant adenomas of the colon and rectum; (adenoma malignum). 61
14891072 1951

Variations for Rectum Adenoma

Expression for Rectum Adenoma

Search GEO for disease gene expression data for Rectum Adenoma.

Pathways for Rectum Adenoma

GO Terms for Rectum Adenoma

Cellular components related to Rectum Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytosolic large ribosomal subunit GO:0022625 8.62 RPL27A RPL19

Biological processes related to Rectum Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 translational initiation GO:0006413 9.4 RPL27A RPL19
2 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 9.37 RPL27A RPL19
3 Notch signaling pathway GO:0007219 9.32 TGFBR2 MYC
4 viral transcription GO:0019083 9.26 RPL27A RPL19
5 SRP-dependent cotranslational protein targeting to membrane GO:0006614 9.16 RPL27A RPL19
6 response to drug GO:0042493 9.13 TGFBR2 S100A10 MYC
7 positive regulation of mesenchymal cell proliferation GO:0002053 8.62 TGFBR2 MYC

Sources for Rectum Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....