Aliases & Classifications for Red-Green Color Blindness

MalaCards integrated aliases for Red-Green Color Blindness:

Name: Red-Green Color Blindness 12 15 17
Colorblindness, Partial, Deutan Series 74
Reduced Red-Green Discrimination 12
Color Blindness, Red-Green 74
Deutan Defect 12
Deuteranopia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13909
ICD9CM 36 368.52
MeSH 45 D003117
SNOMED-CT 69 77479002
ICD10 34 H53.53

Summaries for Red-Green Color Blindness

MalaCards based summary : Red-Green Color Blindness, also known as colorblindness, partial, deutan series, is related to colorblindness, partial, protan series and colorblindness, partial, deutan series, and has symptoms including visual disturbance An important gene associated with Red-Green Color Blindness is OPN1LW (Opsin 1, Long Wave Sensitive), and among its related pathways/superpathways are Metabolism of fat-soluble vitamins and the visual cycle I (vertebrates). Affiliated tissues include eye and testes, and related phenotypes are hematopoietic system and immune system

Related Diseases for Red-Green Color Blindness

Diseases related to Red-Green Color Blindness via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 29)
# Related Disease Score Top Affiliating Genes
1 colorblindness, partial, protan series 30.9 HLA-DMB OPN1LW RHO TEX28 XG
2 colorblindness, partial, deutan series 12.2
3 bornholm eye disease 11.1
4 color blindness 10.5
5 color vision deficiency 10.5
6 stargardt macular degeneration 10.2 ABCA4 RHO
7 cone-rod dystrophy, x-linked, 2 10.2 OPN1LW RPGR
8 severe early-childhood-onset retinal dystrophy 10.2 ABCA4 RPE65
9 retinitis pigmentosa 19 10.2 ABCA4 RHO
10 cone dystrophy 10.1 OPN1LW RHO RPGR
11 stargardt disease 1 10.1 ABCA4 RHO
12 usher syndrome, type iid 10.1 RHO RPGR
13 choroid disease 10.1 RHO RPE65 RPGR
14 degeneration of macula and posterior pole 10.0 ABCA4 RHO RPE65
15 myopia 10.0 OPN1LW RHO RPGR
16 congenital stationary night blindness 10.0 ABCA4 RHO RPE65
17 retinitis pigmentosa 3 10.0 ABCA4 RPGR
18 blue cone monochromacy 10.0 OPN1LW RHO TEX28
19 macular degeneration, age-related, 1 9.9 ABCA4 RHO RPE65
20 fundus albipunctatus 9.9 RHO RPE65
21 yemenite deaf-blind hypopigmentation syndrome 9.8 ABCA4 RHO RPE65 RPGR
22 stargardt disease 9.8 ABCA4 RHO RPE65 RPGR
23 retinal disease 9.8 ABCA4 RHO RPE65 RPGR
24 cone-rod dystrophy 2 9.8 ABCA4 RHO RPE65 RPGR
25 retinal degeneration 9.8 ABCA4 RHO RPE65 RPGR
26 fundus dystrophy 9.8 ABCA4 RHO RPE65 RPGR
27 leber congenital amaurosis 9.8 ABCA4 RHO RPE65 RPGR
28 achromatopsia 9.7 OPN1LW RPE65 RPGR TEX28
29 retinitis pigmentosa 9.6 ABCA4 OPN1LW RHO RPE65 RPGR

Graphical network of the top 20 diseases related to Red-Green Color Blindness:



Diseases related to Red-Green Color Blindness

Symptoms & Phenotypes for Red-Green Color Blindness

UMLS symptoms related to Red-Green Color Blindness:


visual disturbance

MGI Mouse Phenotypes related to Red-Green Color Blindness:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.8 ABCA4 CGAS F8 NLRP3 RHO RPE65
2 immune system MP:0005387 9.7 ABCA4 CGAS F8 NLRP3 RHO RPE65
3 pigmentation MP:0001186 9.26 ABCA4 RHO RPE65 RPGR
4 vision/eye MP:0005391 9.1 ABCA4 OPN1LW RHO RPE65 RPGR ST14

Drugs & Therapeutics for Red-Green Color Blindness

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Biomarker for Duchenne Disease (BioDuchenne) Recruiting NCT02994030

Search NIH Clinical Center for Red-Green Color Blindness

Genetic Tests for Red-Green Color Blindness

Anatomical Context for Red-Green Color Blindness

MalaCards organs/tissues related to Red-Green Color Blindness:

42
Eye, Testes

Publications for Red-Green Color Blindness

Articles related to Red-Green Color Blindness:

# Title Authors Year
1
Bicuculline produces reversible red-green color blindness in goldfish, as revealed by monocular behavioral testing. ( 1663295 )
1991
2
Incidence of red-green color blindness in the Basque population. ( 2378506 )
1990
3
Spectral characteristics of electroretinography in congenital red-green color blindness. ( 3498068 )
1987
4
Spectral characteristics of early receptor potential in congenital red-green color blindness. ( 3488889 )
1986
5
Criterion validity of four tests for red-green color blindness. ( 4536748 )
1972
6
Red/green color blindness in the Niger delta. ( 5298588 )
1967
7
Sex-linked nystagmus associated with red-green color-blindness. ( 17948382 )
1949

Variations for Red-Green Color Blindness

Expression for Red-Green Color Blindness

Search GEO for disease gene expression data for Red-Green Color Blindness.

Pathways for Red-Green Color Blindness

Pathways related to Red-Green Color Blindness according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.59 ABCA4 OPN1LW RHO RPE65
2
Show member pathways
10.54 ABCA4 RHO RPE65
3 10.11 OPN1LW RHO

GO Terms for Red-Green Color Blindness

Cellular components related to Red-Green Color Blindness according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.55 ABCA4 OPN1LW RHO ST14 XG
2 photoreceptor disc membrane GO:0097381 9.13 ABCA4 OPN1LW RHO
3 photoreceptor outer segment GO:0001750 8.92 ABCA4 OPN1LW RHO RPGR

Biological processes related to Red-Green Color Blindness according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 response to stimulus GO:0050896 9.55 ABCA4 OPN1LW RHO RPE65 RPGR
2 photoreceptor cell maintenance GO:0045494 9.46 ABCA4 RHO
3 phototransduction GO:0007602 9.43 OPN1LW RHO
4 response to light stimulus GO:0009416 9.4 RHO RPE65
5 cellular response to light stimulus GO:0071482 9.37 OPN1LW RHO
6 visual perception GO:0007601 9.35 ABCA4 OPN1LW RHO RPE65 RPGR
7 protein-chromophore linkage GO:0018298 9.32 OPN1LW RHO
8 phototransduction, visible light GO:0007603 9.26 ABCA4 RHO
9 retinoid metabolic process GO:0001523 8.92 ABCA4 OPN1LW RHO RPE65

Molecular functions related to Red-Green Color Blindness according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 G protein-coupled photoreceptor activity GO:0008020 8.96 OPN1LW RHO
2 photoreceptor activity GO:0009881 8.62 OPN1LW RHO

Sources for Red-Green Color Blindness

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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