MCID: RFL002
MIFTS: 27

Reflex Epilepsy

Categories: Neuronal diseases

Aliases & Classifications for Reflex Epilepsy

MalaCards integrated aliases for Reflex Epilepsy:

Name: Reflex Epilepsy 12 15
Epilepsy, Reflex 44 73
Epilepsy, Sensory-Induced 12
Epilepsy Reflex 55

Classifications:



External Ids:

Disease Ontology 12 DOID:2548
MeSH 44 D020195
NCIt 50 C85041
SNOMED-CT 68 79745005
UMLS 73 C0270857

Summaries for Reflex Epilepsy

MalaCards based summary : Reflex Epilepsy, also known as epilepsy, reflex, is related to genetic reflex epilepsy and eating reflex epilepsy. An important gene associated with Reflex Epilepsy is WARS (Tryptophanyl-TRNA Synthetase). The drugs Valproic Acid and Anticonvulsants have been mentioned in the context of this disorder. Affiliated tissues include brain, thalamus and temporal lobe.

Related Diseases for Reflex Epilepsy

Diseases related to Reflex Epilepsy via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 genetic reflex epilepsy 12.1
2 eating reflex epilepsy 12.0
3 hot water reflex epilepsy 12.0
4 photosensitive epilepsy 11.3
5 epilepsy, reading 11.0
6 epileptic encephalopathy, early infantile, 8 11.0
7 epilepsy 10.7
8 hyperglycemia 9.8
9 athetosis 9.8
10 glioma 9.8
11 childhood electroclinical syndrome 9.7 TBC1D24 WARS
12 cerebellar hypoplasia 9.7
13 cerebritis 9.7
14 myoclonus 9.7
15 paroxysmal choreoathetosis 9.7
16 epileptic encephalopathy, early infantile, 6 9.5 TBC1D24 WARS

Graphical network of the top 20 diseases related to Reflex Epilepsy:



Diseases related to Reflex Epilepsy

Symptoms & Phenotypes for Reflex Epilepsy

Drugs & Therapeutics for Reflex Epilepsy

Drugs for Reflex Epilepsy (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Valproic Acid Approved, Investigational Phase 4 99-66-1 3121
2 Anticonvulsants Phase 4,Phase 2
3 Antimanic Agents Phase 4,Phase 2
4 Central Nervous System Depressants Phase 4,Phase 2
5 GABA Agents Phase 4,Phase 2
6 Neurotransmitter Agents Phase 4,Phase 2
7 Psychotropic Drugs Phase 4,Phase 2
8 Tranquilizing Agents Phase 4,Phase 2
9
Lorazepam Approved Phase 2 846-49-1 3958
10
Carbamazepine Approved, Investigational Phase 2 298-46-4 2554
11 Etiracetam Investigational Phase 2 33996-58-6
12 Anti-Anxiety Agents Phase 2
13 Antiemetics Phase 2
14 Autonomic Agents Phase 2
15 GABA Modulators Phase 2
16 Gastrointestinal Agents Phase 2
17 Hypnotics and Sedatives Phase 2
18 Peripheral Nervous System Agents Phase 2
19 Analgesics Phase 2
20 Analgesics, Non-Narcotic Phase 2
21 Cytochrome P-450 CYP3A Inducers Phase 2
22 Nootropic Agents Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Effect of Valproic Acid Concentration on Photic Response Completed NCT00609245 Phase 4 Valproic Acid;Placebo
2 Does BRV Have Faster Onset Time & Greater Effect Than LEV in Epilepsy Pts Using PPR Pharmacodynamic Efficacy Endpoint Recruiting NCT03580707 Phase 2, Phase 3 BRV vs LEV in randomized double blinded, crossover fashion
3 PF-06372865 in Subjects With Photosensitive Epilepsy Completed NCT02564029 Phase 2 PF-06372865;Placebo;Lorazepam
4 A Study of the Effects of JNJ-26489112 on the Photic Induced Paroxysmal Electroencephalogram (EEG) Response in Patients With Photosensitive Epilepsy Completed NCT00579384 Phase 2 JNJ-26489112;Placebo
5 Photosensitivity Proof of Concept Trial Completed NCT00894010 Phase 2 carbamazepine 400mg;levetiracetam 1000mg
6 Effect of BGG492 on EEG in Patients With Photosensitive Epilepsy Completed NCT00784212 Phase 2 BGG492;BGG492;Placebo
7 A Study to Evaluate the Effect of ACT-709478 in Photosensitive Epilepsy Patients Recruiting NCT03239691 Phase 2 ACT-709478 for oral use;Placebo

Search NIH Clinical Center for Reflex Epilepsy

Cochrane evidence based reviews: epilepsy, reflex

Genetic Tests for Reflex Epilepsy

Anatomical Context for Reflex Epilepsy

MalaCards organs/tissues related to Reflex Epilepsy:

41
Brain, Thalamus, Temporal Lobe, Occipital Lobe

Publications for Reflex Epilepsy

Articles related to Reflex Epilepsy:

(show top 50) (show all 110)
# Title Authors Year
1
Reflex epilepsy: triggers and management strategies. ( 29403278 )
2018
2
Somatosensory reflex epilepsy: simultaneous video-EEG monitoring and surface EMG. ( 29444763 )
2018
3
Seizures Induced by Exiting Water: A Unique Form of Reflex Epilepsy. ( 28859025 )
2017
4
Features of stimulus-specific seizures in dogs with reflex epilepsy: 43 cases (2000-2014). ( 28001116 )
2017
5
A Rare Reflex Epilepsy: Bathing-Related Epilepsy. ( 28680322 )
2017
6
Intractable ictal vomiting: a new form of reflex epilepsy? ( 28625944 )
2017
7
Role of dietary and lifestyle modifications in reflex epilepsy based on traditional Persian medicine. ( 28088254 )
2017
8
A case of symptomatic reflex epilepsy precipitated by bathing. ( 27668179 )
2016
9
Rub Evoked Reflex Epilepsy in an Infant With Cerebellar Hypoplasia. ( 27268764 )
2016
10
The Pivotal Role of the Parieto-Occipital Lobe in Card Game-Induced Reflex Epilepsy: A Voxel-Based Morphometry Study. ( 27344460 )
2016
11
Genetically epilepsy-prone rats (GEPRs) and DBA/2 mice: Two animal models of audiogenic reflex epilepsy for the evaluation of new generation AEDs. ( 26254980 )
2015
12
Autonomic function in reflex and non-reflex epilepsy - an exploratory study. ( 26369268 )
2015
13
Hot water epilepsy: A form of reflex epilepsy - from infancy to adolescence. ( 26752913 )
2015
14
[Rare cases of reflex epilepsy in patients with gliomas of the left hemisphere]. ( 25406908 )
2014
15
Hot water epilepsy: a video case of European boy with positive family history and subsequent non-reflex epilepsy. ( 24691301 )
2014
16
Understanding the pathophysiology of reflex epilepsy using simultaneous EEG-fMRI. ( 24691294 )
2014
17
Blackouts in the toilet: a case of micturition-induced reflex epilepsy. ( 24567420 )
2014
18
Reflex Epilepsy Triggered by Smell. ( 25013184 )
2014
19
Micturition-induced seizures: a rare form of reflex epilepsy. ( 23827429 )
2013
20
Pure graphogenic epilepsy--a rare form of reflex epilepsy. ( 23786750 )
2013
21
Emotional stress-induced seizures: another reflex epilepsy? ( 22150553 )
2012
22
Opposite caudal versus rostral brain nitric oxide synthase response to generalized seizures in a novel rodent model of reflex epilepsy. ( 22326500 )
2012
23
Reflex epilepsy induced by playing Go-stop or Baduk games. ( 22995679 )
2012
24
Somatosensory rub evoked reflex epilepsy of a temporal lobe origin. ( 20640465 )
2011
25
Lesional reflex epilepsy associated with the thought of food. ( 20644158 )
2010
26
Lesional reflex epilepsy associated with the thought of food. ( 20157165 )
2010
27
Hot water epilepsy: A rare form of reflex epilepsy. ( 21808513 )
2010
28
Familial autosomal dominant reflex epilepsy triggered by hot water maps to 4q24-q28. ( 19597845 )
2009
29
Kinesigenic reflex epilepsy associated with a glioma in the lateral peri-rolandic region. ( 19286490 )
2009
30
A locus for autosomal dominant reflex epilepsy precipitated by hot water maps at chromosome 10q21.3-q22.3. ( 19266219 )
2009
31
Electroclinical characteristics of micturition-induced reflex epilepsy. ( 19204273 )
2009
32
Teaching Video NeuroImage: Electroclinical characteristics of micturition-induced reflex epilepsy. ( 18474839 )
2008
33
Reflex seizures and reflex epilepsy. ( 16605171 )
2006
34
Micturition and emotion-induced reflex epilepsy: case report and review of the literature. ( 17201720 )
2006
35
[Advances in our knowledge of the causation and pathophysiology of reflex epilepsies]. ( 17160926 )
2006
36
Reflex epilepsy induced by playing oriental card or board games. ( 20396530 )
2006
37
Transfer of an avian genetic reflex epilepsy by embryonic brain graft: a tissue autonomous process? ( 15906237 )
2005
38
Mah-Jong-induced epilepsy: a special reflex epilepsy in Chinese society. ( 15642495 )
2005
39
The reflex epilepsies with emphasis on photosensitive epilepsy. ( 16106643 )
2004
40
An avian model of genetic reflex epilepsy. ( 15260383 )
2004
41
Telephone-induced seizures: a new type of reflex epilepsy. ( 15009231 )
2004
42
Reflex epilepsy and non-ketotic hyperglycemia. ( 14684353 )
2003
43
Preventing seizures from "Pocket Monsters": a way to control reflex epilepsy. ( 11723255 )
2001
44
Rub epilepsy: a somatosensory evoked reflex epilepsy induced by prolonged cutaneous stimulation. ( 11254785 )
2001
45
Mah-jong epilepsy: a new reflex epilepsy. ( 10820911 )
2000
46
Postoperative seizure outcome after corpus callosotomy in reflex epilepsy. ( 10746422 )
2000
47
Reflex epilepsy and reflex seizures of the visual system: a clinical review. ( 11022137 )
2000
48
Seizures induced by frustration and despair due to unresolved moral and political issues: a rare case of reflex epilepsy. ( 10064177 )
1999
49
Photosensitive reflex epilepsy. ( 10999132 )
1999
50
Experimental models of reflex epilepsy. ( 9385411 )
1998

Variations for Reflex Epilepsy

Expression for Reflex Epilepsy

Search GEO for disease gene expression data for Reflex Epilepsy.

Pathways for Reflex Epilepsy

GO Terms for Reflex Epilepsy

Sources for Reflex Epilepsy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....