MCID: RGN005
MIFTS: 24

Regional Odontodysplasia

Categories: Oral diseases, Rare diseases

Aliases & Classifications for Regional Odontodysplasia

MalaCards integrated aliases for Regional Odontodysplasia:

Name: Regional Odontodysplasia 59 55
Odontodysplasia 73
Ghost Teeth 59

Characteristics:

Orphanet epidemiological data:

59
regional odontodysplasia
Inheritance: Not applicable; Age of onset: Childhood; Age of death: normal life expectancy;

Classifications:

Orphanet: 59  
Rare odontological diseases


External Ids:

Orphanet 59 ORPHA83450
ICD10 via Orphanet 34 K00.4
UMLS 73 C0206554

Summaries for Regional Odontodysplasia

MalaCards based summary : Regional Odontodysplasia, also known as odontodysplasia, is related to nevus, epidermal and hydrocephalus. An important gene associated with Regional Odontodysplasia is DSPP (Dentin Sialophosphoprotein), and among its related pathways/superpathways are Cytoskeletal Signaling and Embryonic and Induced Pluripotent Stem Cell Differentiation Pathways and Lineage-specific Markers. Related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Wikipedia : 76 Regional odontodysplasia or odontogenesis imperfecta is an uncommon developmental abnormality of teeth,... more...

Related Diseases for Regional Odontodysplasia

Diseases related to Regional Odontodysplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 11)
# Related Disease Score Top Affiliating Genes
1 nevus, epidermal 10.0
2 hydrocephalus 9.9
3 pericoronitis 9.9
4 inflammatory linear verrucous epidermal nevus 9.9
5 liver angiosarcoma 9.5 KRT19 VIM
6 pericardial mesothelioma 9.5 KRT19 VIM
7 sarcoma, synovial 9.4 KRT19 VIM
8 chordoma 9.3 KRT19 VIM
9 adenoid cystic carcinoma 9.2 KRT19 VIM
10 renal cell carcinoma, nonpapillary 9.0 KRT19 VIM
11 odontoma 8.8 DSPP KRT19 VIM

Graphical network of the top 20 diseases related to Regional Odontodysplasia:



Diseases related to Regional Odontodysplasia

Symptoms & Phenotypes for Regional Odontodysplasia

GenomeRNAi Phenotypes related to Regional Odontodysplasia according to GeneCards Suite gene sharing:

26 (show all 12)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.77 VIM
2 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.77 VIM KRT19
3 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.77 KRT19
4 Increased shRNA abundance (Z-score > 2) GR00366-A-176 9.77 VIM
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.77 VIM KRT19
6 Increased shRNA abundance (Z-score > 2) GR00366-A-189 9.77 VIM
7 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.77 VIM
8 Increased shRNA abundance (Z-score > 2) GR00366-A-29 9.77 VIM
9 Increased shRNA abundance (Z-score > 2) GR00366-A-30 9.77 VIM
10 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.77 KRT19
11 Increased shRNA abundance (Z-score > 2) GR00366-A-63 9.77 VIM
12 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.77 VIM

Drugs & Therapeutics for Regional Odontodysplasia

Search Clinical Trials , NIH Clinical Center for Regional Odontodysplasia

Genetic Tests for Regional Odontodysplasia

Anatomical Context for Regional Odontodysplasia

Publications for Regional Odontodysplasia

Articles related to Regional Odontodysplasia:

(show top 50) (show all 82)
# Title Authors Year
1
Cervicofacial infection in a 3-year-old child with regional odontodysplasia: A case report and literature review. ( 29491620 )
2018
2
Clinical, Radiographic, and Histologic Evaluation of Regional Odontodysplasia: a Case Report with 5-year Follow-up. ( 27284563 )
2016
3
Regional Odontodysplasia with Generalised Enamel Defect. ( 28097027 )
2016
4
Inflammatory linear verrucous epidermal nevus and regional odontodysplasia: A rare sorority. ( 26752881 )
2015
5
Ghost teeth: Regional odontodysplasia of maxillary first molar associated with eruption disorders in a 10-year-old girl. ( 26538974 )
2015
6
Regional odontodysplasia: Report of an unusual case involving mandibular arch. ( 26097362 )
2015
7
Oral pathology quiz #82. Case number 1. Regional odontodysplasia. ( 24812725 )
2014
8
Clinical and radiographic findings and usefulness of computed tomographic assessment in two children with regional odontodysplasia. ( 25250179 )
2014
9
Regional odontodysplasia: literature review and report of an unusual case located in the mandible. ( 24717712 )
2014
10
Regional Odontodysplasia: Report of a case. ( 24724145 )
2013
11
Generalised versus Regional Odontodysplasia: Diagnosis, Transitional Management, and Long-Term Followup-A Report of 2 Cases. ( 23476815 )
2013
12
Early diagnosis of regional odontodysplasia in an infant. ( 22446448 )
2012
13
Regional odontodysplasia: a case of progressive tooth development. ( 22918107 )
2012
14
Regional odontodysplasia: a case report. ( 23210194 )
2012
15
Regional odontodysplasia: orthodontic treatment and transplantation of premolars. ( 23116512 )
2012
16
Regional odontodysplasia: report of a case. ( 22449506 )
2012
17
Regional odontodysplasia. A literature review and three case reports. ( 22762183 )
2012
18
Regional Odontodysplasia Crossing Midline: A Rare Case Report. ( 27672258 )
2011
19
Regional odontodysplasia: management of an acute case with a scanning electron microscope. ( 21903559 )
2011
20
Regional odontodysplasia. ( 22016318 )
2011
21
Regional odontodysplasia involving three quadrants of the jaws: a case report. ( 19907727 )
2010
22
Oral and maxillofacial pathology case of the month. Regional odontodysplasia (ghost teeth). ( 20629368 )
2010
23
Regional odontodysplasia. ( 21273724 )
2010
24
Regional odontodysplasia in early childhood: a clinical and histological study. ( 19841550 )
2009
25
Regional odontodysplasia: An unusual case report. ( 21887003 )
2009
26
Long-term management of a child with regional odontodysplasia: a case report. ( 19722446 )
2009
27
Regional odontodysplasia: report of a case in the mandible crossing the midline. ( 18335131 )
2008
28
Regional odontodysplasia: morphological, ultrastructural, and immunohistochemical features of the affected teeth, connective tissue, and odontogenic remnants. ( 18647509 )
2008
29
Regional odontodysplasia of the deciduous and permanent teeth associated with eruption disorders: A case report. ( 18758400 )
2008
30
Progressive dental development in regional odontodysplasia. ( 17613259 )
2007
31
Regional odontodysplasia: case report. ( 19089181 )
2007
32
Conservative management of regional odontodysplasia: case report. ( 17049109 )
2006
33
Regional odontodysplasia: report of case. ( 16937862 )
2006
34
Clinical management of regional odontodysplasia. ( 15839393 )
2005
35
Regional odontodysplasia: report of a case. ( 15554403 )
2004
36
Regional odontodysplasia: a review of the literature and report of four cases. ( 14714196 )
2004
37
Regional odontodysplasia: a review of the literature and report of a case. ( 15331002 )
2004
38
Regional odontodysplasia. A case report. ( 14702762 )
2003
39
Regional odontodysplasia: expression of matrix metalloproteinases and their natural inhibitors. ( 12539028 )
2003
40
Case report: restorative options in regional odontodysplasia. ( 12051133 )
2002
41
Diagnostic quiz #51. Case no. 1: Benign mesenchymal neoplasm. Case no. 2: Regional odontodysplasia. ( 19230272 )
2001
42
Regional odontodysplasia (Ghost teeth). A case report. ( 11987665 )
2001
43
Focal delayed eruption. Regional odontodysplasia. ( 12016676 )
2001
44
Regional odontodysplasia: report of a case involving two separate affected areas. ( 10476360 )
1999
45
Regional odontodysplasia: an unusual case with a conservative approach. ( 10379086 )
1999
46
Ultrastructural organization and microanalysis studies of deciduous enamel crystallites in regional odontodysplasia (RO). ( 9831964 )
1998
47
Autotransplantation for treatment of regional odontodysplasia. Case report with 6-year follow-up. ( 9540088 )
1998
48
Regional odontodysplasia. Report of two cases. ( 9540089 )
1998
49
Regional odontodysplasia: report of four cases. ( 9524463 )
1997
50
An alternative restorative method for regional odontodysplasia: case report. ( 9348609 )
1997

Variations for Regional Odontodysplasia

Expression for Regional Odontodysplasia

Search GEO for disease gene expression data for Regional Odontodysplasia.

Pathways for Regional Odontodysplasia

Pathways related to Regional Odontodysplasia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.64 KRT19 VIM
2 11.08 KRT19 VIM
3
Show member pathways
10.66 KRT19 VIM

GO Terms for Regional Odontodysplasia

Cellular components related to Regional Odontodysplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 intermediate filament GO:0005882 8.62 KRT19 VIM

Biological processes related to Regional Odontodysplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 8.62 KRT19 VIM

Molecular functions related to Regional Odontodysplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.62 KRT19 VIM

Sources for Regional Odontodysplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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