MCID: RGL001
MIFTS: 21

Regular Astigmatism

Categories: Eye diseases

Aliases & Classifications for Regular Astigmatism

MalaCards integrated aliases for Regular Astigmatism:

Name: Regular Astigmatism 12 15 71

Classifications:



External Ids:

Disease Ontology 12 DOID:11781
ICD9CM 34 367.21
SNOMED-CT 67 68905002
ICD10 32 H52.22
UMLS 71 C0152193

Summaries for Regular Astigmatism

MalaCards based summary : Regular Astigmatism is related to astigmatism and keratoconus. An important gene associated with Regular Astigmatism is CYLC1 (Cylicin 1). Affiliated tissues include eye and endothelial.

Related Diseases for Regular Astigmatism

Diseases related to Regular Astigmatism via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 21)
# Related Disease Score Top Affiliating Genes
1 astigmatism 29.8 TRARG1 DPT CYLC1 CER1
2 keratoconus 10.3
3 refractive error 10.2
4 ametropic amblyopia 10.2 DPT CYLC1
5 amblyopia 10.1 DPT CYLC1
6 retinal lattice degeneration 10.1 DPT CYLC1
7 exotropia 10.1 DPT CYLC1
8 esotropia 10.0 DPT CYLC1
9 myopia 10.0
10 cataract 10.0
11 lens disease 10.0 DPT CYLC1
12 cycloplegia 9.8 DPT CYLC1 CER1
13 corneal edema 9.8 VSX1 FBXO7 CYLC1
14 fuchs' endothelial dystrophy 9.8 VSX1 FBXO7
15 irregular astigmatism 9.7 VSX1 TRARG1 CYLC1
16 corneal ectasia 9.7 VSX1 TRARG1 CYLC1
17 cleft soft palate 9.6 TAP1 SLC2A10
18 orthostatic intolerance 9.6 VSX1 SLC2A10
19 anisometropia 9.4 TRARG1 DPT CYLC1 CER1
20 eye accommodation disease 9.3 TRARG1 DPT CYLC1 CER1
21 corneal disease 9.3 VSX1 TRARG1 FBXO7 CYLC1

Graphical network of the top 20 diseases related to Regular Astigmatism:



Diseases related to Regular Astigmatism

Symptoms & Phenotypes for Regular Astigmatism

Drugs & Therapeutics for Regular Astigmatism

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Manually Performed Limbal Relaxing Incisions vs Femtosecond Laser-guided Astigmatic Keratotomy for Correction of Corneal Astigmatism After Phacoemulsification Unknown status NCT03264534
2 Observational Study of Keratoconus and Post-keratoplasty Eyes Completed NCT02109848
3 Visual Performance After Trifocal vs Extended Range of Vision Presbyopia-correcting Intraocular Lenses Completed NCT03974451

Search NIH Clinical Center for Regular Astigmatism

Genetic Tests for Regular Astigmatism

Anatomical Context for Regular Astigmatism

MalaCards organs/tissues related to Regular Astigmatism:

40
Eye, Endothelial

Publications for Regular Astigmatism

Articles related to Regular Astigmatism:

(show top 50) (show all 132)
# Title Authors PMID Year
1
Astigmatism Orientation After Deep Anterior Lamellar Keratoplasty for Keratoconus and Its Correlation With Preoperative Peripheral Corneal Astigmatism. 61
31634226 2020
2
Patient selection to optimize near vision performance with a low-addition trifocal lens. 61
31680039 2020
3
Fourier Analysis of Corneal Irregular Astigmatism After Small Incision Lenticule Extraction and Comparison to Femtosecond Laser-Assisted Laser In Situ Keratomileusis. 61
31232744 2019
4
Femtosecond-Assisted Elliptical LASIK Flap for the Correction of Post-Arcuate Keratotomy Residual Astigmatism. 61
31824289 2019
5
Good Visual Performance Despite Reduced Optical Quality during the First Month of Orthokeratology Lens Wear. 61
31526284 2019
6
Intrastromal Lenticule Rotation for Treatment of Astigmatism Up to 10.00 Diopters Ex Vivo in Human Corneas. 61
31298725 2019
7
Fourier Analysis of Corneal Irregular Astigmatism Due to the Anterior Corneal Surface in Dry Eye. 61
30550406 2019
8
Three-year follow-up of intrastromal corneal ring segment implantation in central keratoconus with regular astigmatism: 'Bow-tie' shape. 61
30845839 2019
9
Relationship of placido corneal topography data with scleral lens fitting parameters. 61
30055934 2019
10
Yield of Display Modules of Corneal Tomography for Early Diagnosis of Corneal Ectasia. 61
31234630 2019
11
Utilizing intraoperative aberrometry and digital eye tracking to develop a novel nomogram for manual astigmatic keratotomy to effectively decrease mild astigmatism during cataract surgery. 61
30993064 2019
12
Threshold Values of Myopic Anisometropia Causing Loss of Stereopsis. 61
31198605 2019
13
Clinical Performance of a Spherical Hybrid Lens Design in High Regular Astigmatism. 61
27660920 2018
14
Validation of Fourier analysis of videokeratographic data. 61
28620708 2018
15
Corneal Irregular Astigmatism and Curvature Changes After Small Incision Lenticule Extraction: Three-Year Follow-Up. 61
29757850 2018
16
[A multicenter study of the effectiveness and safety of Toric intraocular lens implantation]. 61
29747366 2018
17
Overexpression of Tear Inflammatory Cytokines as Additional Finding in Keratoconus Patients and Their First Degree Family Members. 61
30245588 2018
18
Ophthalmic findings in patients with arterial tortuosity syndrome and carriers: A case series. 61
28726533 2018
19
[Predictability of residual astigmatism after implantation of posterior chamber toric lenses]. 61
28289879 2018
20
Axis-free correction of astigmatism using bifocal soft contact lenses. 61
28935527 2017
21
Repair of Irregularly Irregular Astigmatism by Transepithelial Phototherapeutic Keratectomy. 61
28991341 2017
22
Clinical characterization of posterior polymorphous corneal dystrophy in patients of Indian ethnicity. 61
27658681 2017
23
Fourier analysis algorithm for the posterior corneal keratometric data: clinical usefulness in keratoconus. 61
28656673 2017
24
[Evaluation of Postoperative Astigmatism Correction and Postoperative Rotational Stability of Two Toric Intraocular Lenses]. 61
28380650 2017
25
Influences of 27-Gauge Vitrectomy on Corneal Topographic Conditions. 61
28928983 2017
26
Limbal Stem Cell-Sparing Corneoscleroplasty with Peripheral Intralamellar Tuck: A New Surgical Technique for Keratoglobus. 61
28559840 2017
27
Comparison of Long-Term Outcomes of Visual Function and Endothelial Cell Survival After Descemet Stripping Automated Endothelial Keratoplasty and Penetrating Keratoplasty Using Mixed-Effects Models. 61
27560035 2016
28
Effect of Osteopathic Cranial Manipulative Medicine on Visual Function. 61
27802556 2016
29
Fourier analysis of videokeratography data: Clinical usefulness in grade I and subclinical keratoconus. 61
27255250 2016
30
Paediatric Refractive Errors in an Eye Clinic in Osogbo, Nigeria. 61
27222627 2016
31
From corneal shape to ocular wavefront in eyes with aspheric IOLs: the feasibility of IOL customisation. 61
26489033 2016
32
Changes in Irregular Corneal Astigmatism With Age in Eyes With and Without Cataract Surgery. 61
26720446 2015
33
Femtosecond-Assisted Arcuate Keratotomy for the Correction of Postkeratoplasty Astigmatism: Vector Analysis and Accuracy of Laser Incisions. 61
26114816 2015
34
Evaluation of the orientation of the steepest meridian of regular astigmatism among highly myopic Egyptian patients seeking non-ablative surgical correction of the refractive error. 61
26435831 2015
35
Effects of corneal irregular astigmatism on visual acuity after conventional and femtosecond laser-assisted Descemet's stripping automated endothelial keratoplasty. 61
26028117 2015
36
Comparison of two different scheimpflug devices in the detection of keratoconus, regular astigmatism, and healthy corneas. 61
25954510 2015
37
Corneal topographic analysis of patients with Mooren ulcer using 3-dimensional anterior segment optical coherence tomography. 61
25162758 2015
38
Reposition of a misaligned Zeiss AT TORBI 709M® intraocular lens 15 months after implantation. 61
24557755 2014
39
Combined special capsular tension ring and toric IOL implantation for management of post-DALK high regular astigmatism with subluxated traumatic cataract. 61
25116780 2014
40
Results of toric intraocular lenses for post-penetrating keratoplasty astigmatism. 61
24321143 2014
41
The effects of lateral head tilt on ocular astigmatic axis. 61
24592363 2014
42
Treatment of postoperative keratoplasty astigmatism using femtosecond laser-assisted intrastromal relaxing incisions. 61
23739829 2013
43
Effect on corneal shape of suturing the scleral wound during 23-gauge vitreous surgery. 61
22855021 2012
44
Outcomes from a modified microkeratome-assisted lamellar keratoplasty for keratoconus. 61
22801840 2012
45
Combined Descemet-stripping automated endothelial keratoplasty and phacoemulsification with toric intraocular lens implantation for treatment of failed penetrating keratoplasty with high regular astigmatism. 61
22296843 2012
46
Superficial keratectomy, PTK, and mitomycin C as a combined treatment option for Salzmann's nodular degeneration: a follow-up of eight eyes. 61
21465289 2011
47
Limbal relaxing incisions using a reference point and corneal topography for intraoperative identification of the steepest meridian. 61
20954591 2011
48
Peripheral ocular aberrations in mild and moderate keratoconus. 61
20610841 2010
49
Variable ocular phenotypes of posterior polymorphous corneal dystrophy caused by mutations in the ZEB1 gene. 61
21067486 2010
50
Comparison of anterior and posterior corneal surface irregularity in Descemet stripping automated endothelial keratoplasty and penetrating keratoplasty. 61
20567202 2010

Variations for Regular Astigmatism

Expression for Regular Astigmatism

Search GEO for disease gene expression data for Regular Astigmatism.

Pathways for Regular Astigmatism

GO Terms for Regular Astigmatism

Cellular components related to Regular Astigmatism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endomembrane system GO:0012505 8.62 TRARG1 SLC2A10

Sources for Regular Astigmatism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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