MCID: RNR002
MIFTS: 8

Ren-Related Kidney Disease

Categories: Blood diseases, Bone diseases, Genetic diseases, Nephrological diseases

Aliases & Classifications for Ren-Related Kidney Disease

MalaCards integrated aliases for Ren-Related Kidney Disease:

Name: Ren-Related Kidney Disease 25
Hyperuricemic Nephropathy, Familial Juvenile 2 71
Familial Juvenile Hyperuricemic Nephropathy 2 25

Classifications:



External Ids:

UMLS 71 C2751310

Summaries for Ren-Related Kidney Disease

Genetics Home Reference : 25 REN-related kidney disease is an inherited condition that affects kidney function. This condition causes slowly progressive kidney disease that usually becomes apparent during childhood. As this condition progresses, the kidneys become less able to filter fluids and waste products from the body, resulting in kidney failure. Individuals with REN-related kidney disease typically require dialysis (to remove wastes from the blood) or a kidney transplant between ages 40 and 70. REN REN People with REN-related kidney disease sometimes have low blood pressure. They may also have mildly increased levels of potassium in their blood (hyperkalemia). In childhood, people with REN-related kidney disease develop a shortage of red blood cells (anemia), which can cause pale skin, weakness, and fatigue. In this disorder, anemia is usually mild and begins to improve during adolescence. REN REN Many individuals with this condition develop high blood levels of a waste product called uric acid. Normally, the kidneys remove uric acid from the blood and transfer it to urine so it can be excreted from the body. In REN-related kidney disease, the kidneys are unable to remove uric acid from the blood effectively. A buildup of uric acid can cause gout, which is a form of arthritis resulting from uric acid crystals in the joints. Individuals with REN-related kidney disease may begin to experience the signs and symptoms of gout during their twenties. REN REN

MalaCards based summary : Ren-Related Kidney Disease, also known as hyperuricemic nephropathy, familial juvenile 2, is related to hyperuricemic nephropathy, familial juvenile, 2. Affiliated tissues include kidney and skin.

Related Diseases for Ren-Related Kidney Disease

Diseases in the Kidney Disease family:

Acute Kidney Failure Renal Infectious Disease
Chronic Kidney Disease Ren-Related Kidney Disease

Diseases related to Ren-Related Kidney Disease via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 hyperuricemic nephropathy, familial juvenile, 2 12.2

Symptoms & Phenotypes for Ren-Related Kidney Disease

Drugs & Therapeutics for Ren-Related Kidney Disease

Search Clinical Trials , NIH Clinical Center for Ren-Related Kidney Disease

Genetic Tests for Ren-Related Kidney Disease

Anatomical Context for Ren-Related Kidney Disease

MalaCards organs/tissues related to Ren-Related Kidney Disease:

40
Kidney, Skin

Publications for Ren-Related Kidney Disease

Variations for Ren-Related Kidney Disease

Expression for Ren-Related Kidney Disease

Search GEO for disease gene expression data for Ren-Related Kidney Disease.

Pathways for Ren-Related Kidney Disease

GO Terms for Ren-Related Kidney Disease

Sources for Ren-Related Kidney Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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