MCID: RNL013
MIFTS: 28

Renal Adenoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Renal Adenoma

MalaCards integrated aliases for Renal Adenoma:

Name: Renal Adenoma 12 15 72
Renal Cell Adenoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2697
NCIt 50 C8383
SNOMED-CT 68 41627005
UMLS 72 C0334684

Summaries for Renal Adenoma

MalaCards based summary : Renal Adenoma, also known as renal cell adenoma, is related to papillary adenoma and renal oncocytoma. An important gene associated with Renal Adenoma is B3GAT1 (Beta-1,3-Glucuronyltransferase 1), and among its related pathways/superpathways are Primary Focal Segmental Glomerulosclerosis FSGS and Dendritic Cells Developmental Lineage Pathway. The drugs Sirolimus and Everolimus have been mentioned in the context of this disorder. Affiliated tissues include kidney, breast and liver.

Related Diseases for Renal Adenoma

Diseases related to Renal Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 115)
# Related Disease Score Top Affiliating Genes
1 papillary adenoma 30.4 KRT7 AMACR
2 renal oncocytoma 30.2 MME KRT7
3 oncocytoma 30.0 MME KRT7 AMACR
4 clear cell papillary renal cell carcinoma 29.6 MME KRT7 AMACR
5 renal cell carcinoma, nonpapillary 29.5 WT1 MME KRT7 AMACR
6 chromophobe renal cell carcinoma 29.5 MME KRT7
7 metanephric adenoma 29.2 WT1 KRT7 KANK1 AMACR
8 renal cell carcinoma, papillary, 1 28.4 WT1 MME KRT7 B3GAT1 AMACR
9 adenoma 10.7
10 nephrogenic adenoma 10.4 KRT7 AMACR
11 ovarian mucinous adenocarcinoma 10.4 KRT7 AMACR
12 kidney rhabdoid cancer 10.4 WT1 B3GAT1
13 benign mesothelioma 10.4 WT1 KRT7
14 endosalpingiosis 10.4 WT1 KRT7
15 female reproductive endometrioid cancer 10.4 WT1 KRT7
16 adenomatoid tumor 10.4 WT1 KRT7
17 malignant biphasic mesothelioma 10.4 WT1 KRT7
18 carcinosarcoma 10.3 MME KRT7
19 balloon cell malignant melanoma 10.3 MME KRT7
20 cervical adenoma malignum 10.3 MME KRT7
21 peritoneum cancer 10.3 WT1 KRT7
22 cervical mucinous adenocarcinoma 10.3 MME KRT7
23 cystadenoma 10.3 MME KRT7
24 ovarian mucinous neoplasm 10.3 WT1 KRT7
25 malignant leydig cell tumor 10.3 MME KRT7
26 adenomyoma 10.3 MME KRT7
27 sertoli-leydig cell tumor 10.3 WT1 KRT7
28 bladder lymphoma 10.3 MME KRT7
29 spindle cell carcinoma 10.3 KRT7 AMACR
30 breast myoepithelial neoplasm 10.3 MME KRT7
31 breast adenomyoepithelioma 10.3 MME KRT7
32 clear cell adenocarcinoma 10.3 KRT7 AMACR
33 infiltrative basal cell carcinoma 10.2 MME KRT7
34 eccrine sweat gland neoplasm 10.2 MME KRT7
35 pancreatic mucinous cystadenoma 10.2 MME KRT7
36 sex cord-gonadal stromal tumor 10.2 WT1 KRT7
37 mixed cell type cancer 10.2 MME KRT7
38 cystic nephroma 10.2 WT1 MME
39 dysgerminoma 10.2 WT1 KRT7
40 ovary epithelial cancer 10.2 WT1 KRT7
41 malignant ovarian surface epithelial-stromal neoplasm 10.2 WT1 KRT7
42 adenocarcinoma 10.2
43 ovarian cancer 1 10.1 WT1 KRT7
44 uterine sarcoma 10.1 WT1 MME
45 small cell carcinoma 10.1 NCAM1 KRT7
46 gallbladder small cell carcinoma 10.0 NCAM1 KRT7
47 natural killer cell leukemia 10.0 NCAM1 B3GAT1
48 pancreatic serous cystadenoma 10.0 NCAM1 KRT7
49 gastric small cell carcinoma 10.0 NCAM1 B3GAT1
50 urethral diverticulum 10.0 WT1 KRT7 AMACR

Graphical network of the top 20 diseases related to Renal Adenoma:



Diseases related to Renal Adenoma

Symptoms & Phenotypes for Renal Adenoma

Drugs & Therapeutics for Renal Adenoma

Drugs for Renal Adenoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Sirolimus Approved, Investigational Phase 2 53123-88-9 6436030 5284616 46835353
2
Everolimus Approved Phase 2 159351-69-6 6442177 70789204
3
Miconazole Approved, Investigational, Vet_approved Phase 2 22916-47-8 4189
4 Antifungal Agents Phase 2
5 Hormones Phase 2
6 Anti-Infective Agents Phase 2
7 Anti-Bacterial Agents Phase 2
8 Antibiotics, Antitubercular Phase 2
9 Immunosuppressive Agents Phase 2
10 Immunologic Factors Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase II Evaluation of Real-Time, Pharmacokinetically Guided Everolimus in Patients With Hormone Receptor Positive Breast Cancer, Pancreatic Neuroendocrine Tumors (PNET), and Renal Cell Carcinoma Terminated NCT02273752 Phase 2 Everolimus
2 Renal Tumors Classification, Biology, and Banking Study Suspended NCT00898365

Search NIH Clinical Center for Renal Adenoma

Genetic Tests for Renal Adenoma

Anatomical Context for Renal Adenoma

MalaCards organs/tissues related to Renal Adenoma:

41
Kidney, Breast, Liver, Brain, Pancreas, Thyroid, Cerebellum

Publications for Renal Adenoma

Articles related to Renal Adenoma:

(show top 50) (show all 159)
# Title Authors PMID Year
1
Spontaneous Age-Related Histopathological Changes in Microminipigs. 38
31337280 2019
2
The Tumor Entity Denominated "clear cell-papillary renal cell carcinoma" According to the WHO 2016 new Classification, have the Clinical Characters of a Renal Cell Adenoma as does Harbor a Benign Outcome. 38
28695322 2018
3
Differences in Types and Incidence of Neoplasms in Wistar Han and Sprague-Dawley Rats. 38
28068893 2017
4
Renal Cell Carcinomas in Vinylidene Chloride-exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation. 38
26682919 2016
5
Nonclinical safety of the sodium-glucose cotransporter 2 inhibitor empagliflozin. 38
25260362 2014
6
Bilateral giant angiomyolipomas revealed after massive retroperitoneal hemorrhage - A case report. 38
24783424 2014
7
Incidentally detected renal adenomatosis in a patient with urolithiasis: a case report. 38
26328080 2013
8
Renal adenoma in a 5-year-old Labrador retriever: big is not always bad. 38
23904644 2013
9
[Ultrasound and color Doppler imaging for kidney and urinary tract tumors]. 38
22843157 2012
10
Neoplasia of captive yellow sea horses (Hippocampus kuda) and weedy sea dragons (Phyllopteryx taeniolatus). 38
22448509 2012
11
Hematologic, serologic, and histologic profile of aged Siberian hamsters (Phodopus sungorus). 38
21640024 2011
12
Hypertrophic osteopathy associated with a renal adenoma in a cat. 38
21217054 2011
13
High-resolution array CGH of metanephric adenomas: lack of DNA copy number changes. 38
20102400 2010
14
[Osteomyelitis and papillary renal adenoma in a red panda (Ailurus fulgens fulgens)]. 38
19024549 2008
15
One-year chronic toxicity of madder color in F344 rats--induction of preneoplastic/neoplastic lesions in the kidney and liver. 38
18723070 2008
16
Computed tomography of renal cell carcinoma in patients with terminal renal impairment. 38
17324547 2007
17
[Renal adenoma treated with partial nephrectomy: a case report]. 38
17702180 2007
18
Papillary renal adenoma of distal nephron differentiation in a horse. 38
17675811 2007
19
Huge pancreas helps diagnosis in von Hippel-Lindau disease. 38
16763339 2006
20
The genetic basis of kidney cancer: why is tuberous sclerosis complex often overlooked? 38
15579029 2004
21
Metanephric adenoma: case report and review of the literature. 38
15568303 2004
22
Multicentric papillary renal cell carcinoma associated with renal adenomatosis. 38
15028029 2004
23
Histopathological characteristics of spindle-cell proliferative disease in broiler chickens and its experimental reproduction in specific pathogen-free chickens. 38
15107549 2004
24
Diagnostic imaging of a renal adenoma in a Red Oscar (Astronotus ocellatus Cuvier, 1829). 38
15072146 2004
25
Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma? 38
14713847 2004
26
[Sodium nitrite-induced potentiation of spontaneous and 1,2-dimethylhydrazine-induced carcinogenesis in male mice F1 (C57 B1xCBA)]. 38
15755063 2004
27
"Indeterminate" cystic lesion of the kidney partially lined by small cells with clear cytoplasm--malignant or benign? 38
12809919 2003
28
Laparoscopic partial nephrectomy for renal tumor: single center experience comparing clamping and no clamping techniques of the renal vasculature. 38
12544293 2003
29
Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis. 38
12028461 2002
30
[Spontaneous perirenal haematoma caused by a renal adenoma]. 38
12189759 2002
31
Evolving classification of renal cell neoplasia. 38
12113090 2001
32
[Lung carcinoma metastasis in renal adenoma: immunohistochemical study]. 38
11765413 2001
33
Mapping a tumor suppressor gene to chromosome 2p13 in metanephric adenoma by microsatellite allelotyping. 38
11172302 2001
34
Laparoscopic surgery for stage T1 renal cell carcinoma: radical nephrectomy and wedge resection. 38
10895002 2000
35
Benign tumors and tumor-like lesions of the adult kidney. Part II: Benign mesenchymal and mixed neoplasms, and tumor-like lesions. 38
10640201 2000
36
[Cytogenetic investigation of kidney tumors. A supplement to conventional diagnosis]. 38
10487099 1999
37
[Multifocal tubulopapillary tumors of the kidney. Morphologic features and prognosis. Three cases]. 38
10095913 1999
38
Benign tumors and tumor-like lesions of the adult kidney. Part I: Benign renal epithelial neoplasms. 38
10197234 1999
39
Renal adenoma associated with renal cyst formation. 38
9855132 1998
40
Characterization of an ochratoxin-A-dedifferentiated and cloned renal epithelial cell line. 38
9772224 1998
41
[Conservative surgery in metanephric renal adenoma]. 38
9675937 1998
42
[A renal adenoma: a case report and review of diagnostic imaging]. 38
9719940 1998
43
[Metanephric renal adenoma]. 38
9557342 1998
44
Clinicopathologic and interphase cytogenetic analysis of papillary (chromophilic) renal cell carcinoma. 38
9388066 1997
45
Solid variants of papillary (chromophil) renal cell carcinoma: clinicopathologic and genetic features. 38
9331293 1997
46
The Heidelberg classification of renal cell tumours. 38
9390023 1997
47
Simultaneous chromosome 7 and 17 gain and sex chromosome loss provide evidence that renal metanephric adenoma is related to papillary renal cell carcinoma. 38
9224305 1997
48
[A study of papillary renal cell carcinoma. Clinicopathological, immunohistochemical features and its typing]. 38
9234615 1997
49
Humoral hypercalcemia due to an occult renal adenoma. 38
9203187 1997
50
Cytologic and fluorescence in situ hybridization (FISH) examination of metanephric adenoma. 38
9067099 1997

Variations for Renal Adenoma

Expression for Renal Adenoma

Search GEO for disease gene expression data for Renal Adenoma.

Pathways for Renal Adenoma

Pathways related to Renal Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.82 WT1 MME
2 10.49 NCAM1 MME

GO Terms for Renal Adenoma

Sources for Renal Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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