MCID: RNL013
MIFTS: 30

Renal Adenoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Renal Adenoma

MalaCards integrated aliases for Renal Adenoma:

Name: Renal Adenoma 12 15 71
Renal Cell Adenoma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2697
NCIt 50 C8383
SNOMED-CT 67 41627005
UMLS 71 C0334684

Summaries for Renal Adenoma

MalaCards based summary : Renal Adenoma, also known as renal cell adenoma, is related to renal oncocytoma and clear cell papillary renal cell carcinoma. An important gene associated with Renal Adenoma is B3GAT1 (Beta-1,3-Glucuronyltransferase 1), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Primary Focal Segmental Glomerulosclerosis FSGS. Affiliated tissues include kidney, pancreas and thyroid.

Related Diseases for Renal Adenoma

Diseases related to Renal Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 157)
# Related Disease Score Top Affiliating Genes
1 renal oncocytoma 29.9 MME KRT7 CDH16
2 clear cell papillary renal cell carcinoma 29.8 TFE3 MME KRT7 AMACR
3 metanephric adenoma 29.7 WT1 KRT7 KANK1 B3GAT1 AMACR
4 angiomyolipoma 29.5 TFE3 PAX8 MME KRT7
5 mesenchymal cell neoplasm 29.4 TFE3 MME
6 oncocytoma 29.3 PAX2 MME KRT7 CDH16 AMACR
7 renal cell carcinoma, nonpapillary 28.5 WT1 TFE3 PRCC PAX8 PAX2 MME
8 renal cell carcinoma, papillary, 1 28.1 WT1 TFE3 PRCC PAX8 PAX2 MME
9 adenoma 10.7
10 microinvasive cervical squamous cell carcinoma 10.3 WT1 KRT7
11 glandular cystitis 10.3 KRT7 AMACR
12 pericardium cancer 10.3 WT1 KRT7
13 breast neuroendocrine neoplasm 10.3 KRT7 B3GAT1
14 hidradenoma 10.3 MME KRT7
15 middle ear carcinoma 10.3 WT1 KRT7
16 perivascular epithelioid cell tumor 10.3 TFE3 MME
17 ovarian brenner tumor 10.3 WT1 KRT7
18 liver leiomyosarcoma 10.3 WT1 KRT7
19 bladder adenocarcinoma 10.3 KRT7 AMACR
20 subareolar duct papillomatosis 10.3 MME KRT7
21 cervical mucinous adenocarcinoma 10.3 MME KRT7
22 nipple benign neoplasm 10.3 MME KRT7
23 renal cell carcinoma, xp11-associated 10.3 TFE3 PRCC
24 pancreatic serous cystadenocarcinoma 10.3 MME KRT7
25 childhood kidney cell carcinoma 10.3 TFE3 PRCC
26 cervical serous adenocarcinoma 10.3 WT1 MME
27 mixed epithelial stromal tumour 10.3 MME KRT7
28 ovarian mucinous adenocarcinoma 10.3 KRT7 AMACR
29 rete testis neoplasm 10.3 PAX8 KRT7
30 breast metaplastic carcinoma 10.3 MME KRT7
31 orbital cellulitis 10.3 MME KRT7
32 rete testis adenocarcinoma 10.3 PAX8 KRT7
33 acute orbital inflammation 10.3 MME KRT7
34 balloon cell malignant melanoma 10.3 MME KRT7
35 bartholin's gland carcinoma 10.3 PAX8 KRT7
36 prostatic acinar adenocarcinoma 10.2 PAX8 AMACR
37 pancreatic mucinous cystadenoma 10.2 MME KRT7
38 renal pelvis adenocarcinoma 10.2 PAX8 KRT7
39 krukenberg carcinoma 10.2 PAX8 KRT7
40 benign peritoneal mesothelioma 10.2 WT1 KRT7
41 squamous papillomatosis 10.2 MME KRT7
42 ovarian endometrioid stromal sarcoma 10.2 WT1 MME
43 cutaneous adenocystic carcinoma 10.2 MME KRT7
44 colon leiomyosarcoma 10.2 WT1 PAX8
45 intraductal breast benign neoplasm 10.2 MME KRT7
46 breast benign neoplasm 10.2 MME KRT7
47 ovarian mucinous neoplasm 10.2 PAX8 KRT7
48 central epithelioid sarcoma 10.2 MME KRT7
49 vulvar proximal-type epithelioid sarcoma 10.2 MME KRT7
50 retroperitoneum carcinoma 10.2 WT1 KRT7

Graphical network of the top 20 diseases related to Renal Adenoma:



Diseases related to Renal Adenoma

Symptoms & Phenotypes for Renal Adenoma

Drugs & Therapeutics for Renal Adenoma

Search Clinical Trials , NIH Clinical Center for Renal Adenoma

Genetic Tests for Renal Adenoma

Anatomical Context for Renal Adenoma

MalaCards organs/tissues related to Renal Adenoma:

40
Kidney, Pancreas, Thyroid, Brain, Cerebellum, Colon, Pons

Publications for Renal Adenoma

Articles related to Renal Adenoma:

(show top 50) (show all 163)
# Title Authors PMID Year
1
Urogenital Lesions in Nonhuman Primates at 2 National Primate Research Centers. 61
33208023 2021
2
Epizootic neoplasia in a managed population of Atlantic bumper fish, Chloroscombrus chrysurus (Osteichthyes: Carangidae), at a public aquarium. 61
33348452 2020
3
Single-Incision Laparoscopic Deroofing and Omentalization of a Cystic Renal Adenoma in a Dog. 61
33113559 2020
4
Erratum for the Research Article: "Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells" by A. J. Peired, G. Antonelli, M. L. Angelotti, M. Allinovi, F. Guzzi, A. Sisti, R. Semeraro, C. Conte, B. Mazzinghi, S. Nardi, M. E. Melica, L. De Chiara, E. Lazzeri, L. Lasagni, T. Lottini, S. Landini, S. Giglio, A. Mari, F. Di Maida, A. Antonelli, F. Porpiglia, R. Schiavina, V. Ficarra, D. Facchiano, M. Gacci, S. Serni, M. Carini, G. J. Netto, R. M. Roperto, A. Magi, C. F. Christiansen, M. Rotondi, H. Liapis, H.-J. Anders, A. Minervini, M. R. Raspollini, P. Romagnani. 61
32581133 2020
5
Acute kidney injury promotes development of papillary renal cell adenoma and carcinoma from renal progenitor cells. 61
32213630 2020
6
Spontaneous Age-Related Histopathological Changes in Microminipigs. 61
31337280 2019
7
The Tumor Entity Denominated "clear cell-papillary renal cell carcinoma" According to the WHO 2016 new Classification, have the Clinical Characters of a Renal Cell Adenoma as does Harbor a Benign Outcome. 61
28695322 2018
8
Differences in Types and Incidence of Neoplasms in Wistar Han and Sprague-Dawley Rats. 61
28068893 2017
9
Renal Cell Carcinomas in Vinylidene Chloride-exposed Male B6C3F1 Mice Are Characterized by Oxidative Stress and TP53 Pathway Dysregulation. 61
26682919 2016
10
Nonclinical safety of the sodium-glucose cotransporter 2 inhibitor empagliflozin. 61
25260362 2014
11
Bilateral giant angiomyolipomas revealed after massive retroperitoneal hemorrhage - A case report. 61
24783424 2014
12
Incidentally detected renal adenomatosis in a patient with urolithiasis: a case report. 61
26328080 2013
13
Renal adenoma in a 5-year-old Labrador retriever: big is not always bad. 61
23904644 2013
14
[Ultrasound and color Doppler imaging for kidney and urinary tract tumors]. 61
22843157 2012
15
Neoplasia of captive yellow sea horses (Hippocampus kuda) and weedy sea dragons (Phyllopteryx taeniolatus). 61
22448509 2012
16
Hematologic, serologic, and histologic profile of aged Siberian hamsters (Phodopus sungorus). 61
21640024 2011
17
Hypertrophic osteopathy associated with a renal adenoma in a cat. 61
21217054 2011
18
High-resolution array CGH of metanephric adenomas: lack of DNA copy number changes. 61
20102400 2010
19
[Osteomyelitis and papillary renal adenoma in a red panda (Ailurus fulgens fulgens)]. 61
19024549 2008
20
One-year chronic toxicity of madder color in F344 rats--induction of preneoplastic/neoplastic lesions in the kidney and liver. 61
18723070 2008
21
Computed tomography of renal cell carcinoma in patients with terminal renal impairment. 61
17324547 2007
22
[Renal adenoma treated with partial nephrectomy: a case report]. 61
17702180 2007
23
Papillary renal adenoma of distal nephron differentiation in a horse. 61
17675811 2007
24
Huge pancreas helps diagnosis in von Hippel-Lindau disease. 61
16763339 2006
25
The genetic basis of kidney cancer: why is tuberous sclerosis complex often overlooked? 61
15579029 2004
26
Metanephric adenoma: case report and review of the literature. 61
15568303 2004
27
Multicentric papillary renal cell carcinoma associated with renal adenomatosis. 61
15028029 2004
28
Histopathological characteristics of spindle-cell proliferative disease in broiler chickens and its experimental reproduction in specific pathogen-free chickens. 61
15107549 2004
29
Diagnostic imaging of a renal adenoma in a Red Oscar (Astronotus ocellatus Cuvier, 1829). 61
15072146 2004
30
Down-regulation of HLA class I antigen processing molecules: an immune escape mechanism of renal cell carcinoma? 61
14713847 2004
31
[Sodium nitrite-induced potentiation of spontaneous and 1,2-dimethylhydrazine-induced carcinogenesis in male mice F1 (C57 B1xCBA)]. 61
15755063 2004
32
"Indeterminate" cystic lesion of the kidney partially lined by small cells with clear cytoplasm--malignant or benign? 61
12809919 2003
33
Laparoscopic partial nephrectomy for renal tumor: single center experience comparing clamping and no clamping techniques of the renal vasculature. 61
12544293 2003
34
Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis. 61
12028461 2002
35
[Spontaneous perirenal haematoma caused by a renal adenoma]. 61
12189759 2002
36
Evolving classification of renal cell neoplasia. 61
12113090 2001
37
[Lung carcinoma metastasis in renal adenoma: immunohistochemical study]. 61
11765413 2001
38
Mapping a tumor suppressor gene to chromosome 2p13 in metanephric adenoma by microsatellite allelotyping. 61
11172302 2001
39
Laparoscopic surgery for stage T1 renal cell carcinoma: radical nephrectomy and wedge resection. 61
10895002 2000
40
Benign tumors and tumor-like lesions of the adult kidney. Part II: Benign mesenchymal and mixed neoplasms, and tumor-like lesions. 61
10640201 2000
41
[Cytogenetic investigation of kidney tumors. A supplement to conventional diagnosis]. 61
10487099 1999
42
Benign tumors and tumor-like lesions of the adult kidney. Part I: Benign renal epithelial neoplasms. 61
10197234 1999
43
[Multifocal tubulopapillary tumors of the kidney. Morphologic features and prognosis. Three cases]. 61
10095913 1999
44
Characterization of an ochratoxin-A-dedifferentiated and cloned renal epithelial cell line. 61
9772224 1998
45
[Conservative surgery in metanephric renal adenoma]. 61
9675937 1998
46
[A renal adenoma: a case report and review of diagnostic imaging]. 61
9719940 1998
47
[Metanephric renal adenoma]. 61
9557342 1998
48
Clinicopathologic and interphase cytogenetic analysis of papillary (chromophilic) renal cell carcinoma. 61
9388066 1997
49
The Heidelberg classification of renal cell tumours. 61
9390023 1997
50
Solid variants of papillary (chromophil) renal cell carcinoma: clinicopathologic and genetic features. 61
9331293 1997

Variations for Renal Adenoma

Expression for Renal Adenoma

Search GEO for disease gene expression data for Renal Adenoma.

Pathways for Renal Adenoma

Pathways related to Renal Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.21 WT1 TFE3 PRCC PAX8
2 11 WT1 PAX2 MME
3 10.36 PAX8 PAX2

GO Terms for Renal Adenoma

Biological processes related to Renal Adenoma according to GeneCards Suite gene sharing:

(show all 22)
# Name GO ID Score Top Affiliating Genes
1 kidney development GO:0001822 9.78 WT1 PAX8 MME
2 branching involved in ureteric bud morphogenesis GO:0001658 9.61 WT1 PAX8 PAX2
3 positive regulation of branching involved in ureteric bud morphogenesis GO:0090190 9.6 PAX8 PAX2
4 urogenital system development GO:0001655 9.59 PAX8 PAX2
5 mesonephros development GO:0001823 9.58 PAX8 PAX2
6 mesenchymal to epithelial transition GO:0060231 9.58 WT1 PAX2
7 metanephric mesenchyme development GO:0072075 9.57 WT1 PAX2
8 cellular response to gonadotropin stimulus GO:0071371 9.56 WT1 PAX8
9 mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0003337 9.55 PAX8 PAX2
10 regulation of metanephric nephron tubule epithelial cell differentiation GO:0072307 9.54 PAX8 PAX2
11 pronephros development GO:0048793 9.52 PAX8 PAX2
12 metanephric S-shaped body morphogenesis GO:0072284 9.51 WT1 PAX8
13 metanephric nephron tubule formation GO:0072289 9.49 PAX8 PAX2
14 metanephric distal convoluted tubule development GO:0072221 9.48 PAX8 PAX2
15 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis GO:0072108 9.46 PAX8 PAX2
16 positive regulation of metanephric DCT cell differentiation GO:2000594 9.4 PAX8 PAX2
17 negative regulation of apoptotic process involved in metanephric nephron tubule development GO:1900218 9.37 PAX8 PAX2
18 negative regulation of apoptotic process involved in metanephric collecting duct development GO:1900215 9.32 PAX8 PAX2
19 negative regulation of mesenchymal cell apoptotic process involved in metanephros development GO:1900212 9.26 PAX8 PAX2
20 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis GO:0072305 9.16 PAX8 PAX2
21 pronephric field specification GO:0039003 8.96 PAX8 PAX2
22 metanephric epithelium development GO:0072207 8.8 WT1 PAX8 PAX2

Molecular functions related to Renal Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcription regulatory region sequence-specific DNA binding GO:0000976 8.92 WT1 TFE3 PAX8 PAX2

Sources for Renal Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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