MCID: RNL001
MIFTS: 33

Renal Artery Obstruction

Categories: Cardiovascular diseases, Nephrological diseases

Aliases & Classifications for Renal Artery Obstruction

MalaCards integrated aliases for Renal Artery Obstruction:

Name: Renal Artery Obstruction 12 43 15 17 71

Classifications:



External Ids:

Disease Ontology 12 DOID:2972
MeSH 43 D012078
ICD10 32 N28.0
UMLS 71 C0035066

Summaries for Renal Artery Obstruction

MalaCards based summary : Renal Artery Obstruction is related to anuria and renovascular hypertension. An important gene associated with Renal Artery Obstruction is REN (Renin), and among its related pathways/superpathways are Microglia Activation During Neuroinflammation: Overview and Agents Acting on the Renin-Angiotensin System Pathway, Pharmacodynamics. The drugs Ticlopidine and Lercanidipine have been mentioned in the context of this disorder. Affiliated tissues include kidney, heart and testes, and related phenotypes are Decreased substrate adherent cell growth and Decreased substrate adherent cell growth

Related Diseases for Renal Artery Obstruction

Diseases related to Renal Artery Obstruction via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 81)
# Related Disease Score Top Affiliating Genes
1 anuria 30.2 REN ACE
2 renovascular hypertension 30.1 REN ACE
3 uremia 29.1 REN ACE
4 hypoaldosteronism 10.2 REN ACE
5 orthostatic proteinuria 10.2 REN ACE
6 hypertension, diastolic 10.2 REN ACE
7 cholesterol embolism 10.2 REN ACE
8 kidney papillary necrosis 10.2 REN ACE
9 generalized atherosclerosis 10.2 REN ACE
10 potter's syndrome 10.2 REN ACE
11 hypertensive encephalopathy 10.2 REN ACE
12 severe nonproliferative diabetic retinopathy 10.2 REN ACE
13 malignant essential hypertension 10.2 REN ACE
14 fibromuscular dysplasia 10.2 REN ACE
15 kidney hypertrophy 10.2 REN ACE
16 hypertensive retinopathy 10.2 REN ACE
17 pure autonomic failure 10.2 REN ACE
18 renal artery disease 10.2 REN ACE
19 central sleep apnea 10.2 REN ACE
20 sleep apnea 10.2 REN ACE
21 cardiac tamponade 10.2 REN ACE
22 alcoholic cardiomyopathy 10.2 REN ACE
23 chronic pyelonephritis 10.2 REN ACE
24 diabetic autonomic neuropathy 10.2 REN ACE
25 pseudohyperkalemia, familial, 2, due to red cell leak 10.2 REN ACE
26 aortic valve insufficiency 10.2 REN ACE
27 mitral valve stenosis 10.2 REN ACE
28 microvascular complications of diabetes 3 10.2 REN ACE
29 pyelitis 10.2 REN ACE
30 renal tubular dysgenesis 10.2 REN ACE
31 acute kidney tubular necrosis 10.2 REN ACE
32 hepatorenal syndrome 10.2 REN ACE
33 mitral valve insufficiency 10.2 REN ACE
34 intermediate coronary syndrome 10.2 REN ACE
35 autonomic nervous system disease 10.2 REN ACE
36 malignant hypertension 10.2 REN ACE
37 pericardium disease 10.2 REN ACE
38 diastolic heart failure 10.2 REN ACE
39 ureteral disease 10.2 REN ACE
40 apnea, obstructive sleep 10.2 REN ACE
41 renal hypertension 10.1 REN ACE
42 renal dysplasia 10.1 REN ACE
43 pericardial effusion 10.1 REN ACE
44 hypertensive heart disease 10.1 REN ACE
45 acute cystitis 10.1 REN ACE
46 mineral metabolism disease 10.1 REN ACE
47 extrinsic cardiomyopathy 10.1 REN ACE
48 mitral valve disease 10.1 REN ACE
49 carotid stenosis 10.1 REN ACE
50 interstitial nephritis 10.1 REN ACE

Graphical network of the top 20 diseases related to Renal Artery Obstruction:



Diseases related to Renal Artery Obstruction

Symptoms & Phenotypes for Renal Artery Obstruction

GenomeRNAi Phenotypes related to Renal Artery Obstruction according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased substrate adherent cell growth GR00193-A-1 9.02 ADORA1 ADORA2B ADORA3
2 Decreased substrate adherent cell growth GR00193-A-3 9.02 ADORA1 ADORA2B

MGI Mouse Phenotypes related to Renal Artery Obstruction:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.02 ACE ADORA1 ADORA2B ADORA3 REN

Drugs & Therapeutics for Renal Artery Obstruction

Drugs for Renal Artery Obstruction (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 80)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ticlopidine Approved Phase 4 55142-85-3 5472
2
Lercanidipine Approved, Investigational Phase 4 100427-26-7 65866
3
Acetylcysteine Approved, Investigational Phase 4 616-91-1 12035
4
Clopidogrel Approved Phase 4 120202-66-6, 113665-84-2 60606
5
Indapamide Approved Phase 4 26807-65-8 3702
6
Aspirin Approved, Vet_approved Phase 4 50-78-2 2244
7
Amlodipine Approved Phase 4 88150-42-9 2162
8
Atorvastatin Approved Phase 4 134523-00-5 60823
9
Furosemide Approved, Vet_approved Phase 4 54-31-9 3440
10
Irbesartan Approved, Investigational Phase 4 138402-11-6 3749
11
Bisoprolol Approved Phase 4 66722-44-9 2405
12
Spironolactone Approved Phase 4 1952-01-7, 52-01-7 5833
13
Rilmenidine Approved, Investigational Phase 4 54187-04-1
14
Prazosin Approved Phase 4 19216-56-9 4893
15
Calcium Approved, Nutraceutical Phase 4 7440-70-2 271
16 Hypoglycemic Agents Phase 4
17 Neurotransmitter Agents Phase 4
18 Platelet Aggregation Inhibitors Phase 4
19 Calcium, Dietary Phase 4
20 calcium channel blockers Phase 4
21 Purinergic P2Y Receptor Antagonists Phase 4
22 Hormones Phase 4
23 Pharmaceutical Solutions Phase 4
24 Respiratory System Agents Phase 4
25 Antioxidants Phase 4
26 Free Radical Scavengers Phase 4
27 Antiviral Agents Phase 4
28 N-monoacetylcystine Phase 4
29 Protective Agents Phase 4
30 Antidotes Phase 4
31 Expectorants Phase 4
32 Antihypertensive Agents Phase 4
33 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
34
Angiotensin II Approved, Investigational Phase 3 68521-88-0, 4474-91-3, 11128-99-7 172198
35
Candesartan cilexetil Approved Phase 3 145040-37-5 2540
36
Ginseng Approved, Investigational, Nutraceutical Phase 2, Phase 3 50647-08-0
37
Candesartan Experimental Phase 3 139481-59-7 2541
38 Angelica Phase 2, Phase 3
39 Astragalus Phase 2, Phase 3
40 Chinese Rhubarb Phase 2, Phase 3
41 Anticholesteremic Agents Phase 2, Phase 3
42 Angiotensin Receptor Antagonists Phase 3
43 Rosuvastatin Calcium Phase 2, Phase 3 147098-20-2
44 Hypolipidemic Agents Phase 2, Phase 3
45 Lipid Regulating Agents Phase 2, Phase 3
46 Antimetabolites Phase 2, Phase 3
47 Angiotensin II Type 1 Receptor Blockers Phase 3
48 Giapreza Phase 3
49 Amlodipine, atorvastatin drug combination Phase 3
50 Angiotensinogen Phase 3

Interventional clinical trials:

(show all 47)
# Name Status NCT ID Phase Drugs
1 Comparison of Stenting Versus Best Medical Therapy for Treatment of Ostial Renal Artery Stenosis: a Randomized Controlled Trial in Patients With Advanced Atherosclerosis. Unknown status NCT00711984 Phase 4
2 Phase 4 Study of Medical Therapy Versus Medical Therapy Plus Renal Artery Stenting in Preventing the Progression of Renal Failure in Atherosclerotic Renovascular Disease Unknown status NCT01023373 Phase 4 Medical treatment
3 Endovascular Treatment Versus Optimal Medical Treatment of Atherosclerotic Renal Artery for Preserving Renal Function of the Ischemic Kidney. Unknown status NCT01208714 Phase 4 Optimal medical therapy
4 The Efficacy of Renal Artery Stent Combined With Standardized Medical Therapy in Patients With Atherosclerotic Renal Artery Stenosis Completed NCT02594410 Phase 4 Aspirine;Clopidogrel;Lercanidipine
5 Safety of Low Dose Intravenous Contrast 64 Multi-Detector Computed Tomography Scanning in Patients With Chronic Kidney Disease Completed NCT02476526 Phase 4 Low Volume iso-osmolar non-ionic radio contrast medium;Acetylcysteine Inhalation;Sodium Bicarbonate Solution
6 Optimum and Stepped Care Standardised Antihypertensive Treatment With or Without Renal Artery Stenting in Patients With Documented Resistant Hypertension and Atherosclerotic Renal Artery Stenosis. ANDORRA TRIAL Terminated NCT02539810 Phase 4 Anti hypertensive, statin and antiplatelet medication.
7 The Evaluation Studies of Curative Effect of Fu-zheng-qu-zhuo Oral Liquid in Treatment of Ischemic Nephropathy Unknown status NCT02044835 Phase 2, Phase 3 Fu-zheng-qu-zhuo oral liquid
8 Percutaneous Renal Stenting in Renovascular Disease With or Without Distal Atheroembolic Protection Unknown status NCT00868972 Phase 2, Phase 3
9 Renal Artery Stenosis in Coronary Artery Disease: Medical Therapy Versus Medical Therapy Plus Renal Artery Stenting in Preventing Cardiac and Renal Outcomes. The Rationale and Study Design of a Prospective,Randomized Trial: the RASCAD Study Unknown status NCT01173666 Phase 3 Medical therapy
10 A Prospective, Randomized Trial to Compare Effects of Intensive Versus Conventional Lipid-lowering Therapy in Patients With Severe Atherosclerotic Renal Artery Stenosis Undergoing Stent Placement Completed NCT03521700 Phase 2, Phase 3 Rosuvastatin
11 Multicenter, Open-label Study to Evaluate the Safety and Efficacy (by Blinded Reading) of Gadobutrol-enhanced Magnetic Resonance Angiography (MRA) After a Single Injection of 0.1 mmol/kg of Gadobutrol in Subjects With Known or Suspected Renal Artery Disease Completed NCT01344460 Phase 3 Gadobutrol (Gadovist, BAY86-4875)
12 A Randomized, Multi-centre, Prospective Study Comparing Best Medical Treatment Versus Best Medical Treatment Plus Renal Artery Stenting in Patients With Hemodynamically Relevant Atherosclerotic Renal Artery Stenosis Completed NCT00640406 Phase 3 Best Medical Treatment
13 A Multicentre, Phase 3, Open-Label, Controlled Study Evaluating the Efficacy and Safety of 0.1 mmol/kg OMNISCAN (Gadodiamide Injection) in Magnetic Resonance Angiography (MRA) of the Renal Arteries Completed NCT00209391 Phase 3 Gadodiamide Injection
14 Multicenter, Open-label Study of the Safety (Open-label) and Efficacy (Open-label and Blinded Reader) of a Single Administration of Approximately 0.1 mmol/kg of Magnevist® Injection-enhanced Magnetic Resonance Arteriography (MRA) and 2-dimensional-time-of-flight (2D-TOF) MRA in Patients With Known or Suspected Renal Artery Disease Undergoing MRA of the Renal Arteries With Intra-arterial Digital Subtraction Arteriography (i.a. DSA) as the Standard of Reference Completed NCT00310557 Phase 3 Gadopentetate dimeglumine (Magnevist)
15 The Benefit of STent Placement and Blood Pressure and Lipid-Lowering for the Prevention of Progression of Renal Dysfunction Caused by Atherosclerotic Ostial Stenosis of the Renal Artery (STAR) Completed NCT00150943 Phase 3
16 Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) Completed NCT00081731 Phase 3 Atacand/HCT, Caduet
17 Evaluation of Dotarem-enhanced Magnetic Resonance Angiography (MRA) Compared to Time-Of-Flight (TOF) MRA in the Diagnosis of Renal Arterial Disease Terminated NCT00845702 Phase 3 Gadoterate meglumine (Dotarem)
18 A Prospective, Non-Randomized, Multicenter, Single-Arm, Clinical Trial to Assess the Safety and Efficacy of the RX HERCULINK 14 Peripheral Stent System for Treatment in de Novo or Restenotic Renal Artery Stenosis Terminated NCT00180544 Phase 3
19 Palmaz Genesis Peripheral Stainless Steel Balloon Expandable Stent, Comparing a Sirolimus Coated Versus an Uncoated Stent in REnal Artery Treatment. Completed NCT00235157 Phase 2
20 Renal Blood Flow Measurement With PET Completed NCT00714142 Phase 2 62Cu-ethylglyoxal bis(thiosemicarbazone);15O-water
21 A Prospective Randomized Multicenter Study Comparing the Safety and Efficacy of Renal Artery Stenting With/Without Distal Protection Device (AngioGuard) and With/Without the Use of a Platelet Aggregator Inhibitor (Abciximab-Reopro) (RESIST) Completed NCT00234585 Phase 2
22 Impact of a Ciclosporin A Preconditioning for Prevention of Ischemia-reperfusion Injury After Renal Artery Stenosis Dilation Recruiting NCT03382301 Phase 2 Ciclosporin A preconditioning before renal artery stenosis dilation;NaCl preconditioning before renal artery stenosis dilation
23 A Phase 2a, Randomized, Placebo-controlled, Single Center Trial to Evaluate the Impact of Intravenous Bendavia™ (MTP-131) on Ischemia Reperfusion Injury in Atherosclerotic Renal Artery Stenosis in Patients Undergoing Percutaneous Transluminal Angioplasty of the Renal Artery (PTRA) Terminated NCT01755858 Phase 1, Phase 2 Bendavia;Placebo
24 Phase I Study of Autologous Mesenchymal Stem Cells in the Treatment of Atherosclerotic Renal Artery Stenosis Completed NCT01840540 Phase 1 Arterial infusion of autologous mesenchymal stem cells
25 Evidence of Procedural Embolism Complicating Renal Artery Stenting Completed NCT00027469 Phase 1
26 Hypoxia and Inflammatory Injury in Human Renovascular Hypertension : Phase 1 Trial of Mesenchymal Stem Cell Therapy Active, not recruiting NCT02266394 Phase 1 Mesenchymal stem cell
27 A Prospective Study of Using Parenchymal Blood Volume(PBV) for Endovascular Treatment of Renal Arterial Stenosis Unknown status NCT03252639
28 Cardiovascular, Renal and Metabolic Profile in Patients With Acute Myocardial Infarction (AMI) Included in the Romanian National Programme of Primary Percutaneous Revascularisation - a Single Center Observational Study Unknown status NCT02388139
29 Hydration Status Assessment Through Body Composition Monitoring And Renal Artery Stenosis Evaluation in Patients With Acute Myocardial Infarction Referred For Primary PCI Unknown status NCT02655341
30 Prognostic Value of Renal Fractional Flow Reserve in Hypertensive Patients With Renal Artery Stenosis Qualified to Renal Artery Stenting Completed NCT01128933
31 REFORM Clinical Study: Treatment of Renal Artery Stenosis With the Formula Balloon-Expandable Stent Completed NCT00631540
32 A Clinical Trial to Assess the Safety and Efficacy of the RX Herculink(R) Elite(TM) Renal Stent System for the Treatment of Suboptimal Post-procedural Percutaneous Transluminal Angioplasty (PTA) in de Novo or Restenotic Renal Artery Stenoses in Patients With Uncontrolled Hypertension. Completed NCT00490841
33 Evaluation of Safety and Effectiveness of the Formula PTX Balloon-Expandable Stent for Renal Artery Stenosis Completed NCT01057316
34 Renal Arteries Dysplastic Aneurysms: Anatomopathological and Genetic Study Completed NCT02528149
35 A 15-year Single Center Experience of Endovascular Treatment of Transplant Renal Artery Stenosis: Evaluation of Post-operative Outcomes Completed NCT03477071
36 Evaluation of Patients With Known or Suspected Heart Disease (Screening Protocol) Completed NCT00001313
37 Prevalence of Renal Artery Stenosis in Patients Refered for Cardiac Catheterization to Heart Center Hospital in July-September 2008 Completed NCT00885768
38 Comparison of Non-contrast Renal Artery Magnetic Resonance Angiography With Contrast-enhanced CT Angiography Completed NCT01576835
39 PROgression of FIbromuscular LEsions Completed NCT02961868
40 Assessment of Renal and Cervical Artery DysplasIA Completed NCT02884141
41 A Prospective Danish National Registry of Percutaneous Transluminal Renal Angioplasty in Patients With Renovascular Hypertension Recruiting NCT02770066
42 To Asses Hemodynamic Disturbances to the Ostia of the Renal Arteries Generated by the Implantation of EVAR With a Suprarenal Fixation Recruiting NCT03594786
43 On-table Renal Perfusion Evaluation for Patients With Renal Artery Stenosis or Aortic Dissection With Renal Artery Obstruction Recruiting NCT03530748
44 ARTISAN: iCAST™ RX De Novo Stent Placement for the Treatment of Atherosclerotic Renal Artery Stenosis in Patients With Resistant Hypertension Active, not recruiting NCT01673373
45 A Multicenter Registry of Endovascular Therapy for Renal Artery Stenosis in China Not yet recruiting NCT03080519
46 Ultrasound Wave Therapy for Post-stenotic Microvascular Remodeling Not yet recruiting NCT03914157
47 The Effects and Safety of Drug-coated Balloon in the Treatment of Hypertension Caused by Takayasu Arteritis Associated Renal Artery Stenosis: a Single Centre, Random, Double Blind Trial Not yet recruiting NCT04137614

Search NIH Clinical Center for Renal Artery Obstruction

Cochrane evidence based reviews: renal artery obstruction

Genetic Tests for Renal Artery Obstruction

Anatomical Context for Renal Artery Obstruction

MalaCards organs/tissues related to Renal Artery Obstruction:

40
Kidney, Heart, Testes

Publications for Renal Artery Obstruction

Articles related to Renal Artery Obstruction:

(show top 50) (show all 63)
# Title Authors PMID Year
1
Complete post-operative resolution of "temporary" end-stage kidney disease secondary to aortic dissection without static renal artery obstruction: a case study. 61
31615429 2019
2
Rare complication of subacute renal artery intramural haematoma after renal artery stenting: a case report. 61
31449593 2019
3
Treatment of a recurrent renal artery stenosis and stent fracture using a drug eluting stent in a pediatric patient. 61
28509158 2016
4
Renovascular acute renal failure precipitated by extracorporeal shock wave lithotripsy for pancreatic stones. 61
26251710 2015
5
Mechanism of stent failure in a patient with fibromuscular dysplasia following renal artery stenting. 61
25192822 2015
6
Postoperative "Chimney" for Unintentional Renal Artery Occlusion after EVAR. 61
25478283 2014
7
Aortic intussusception complicating diagnostic angiography: recognition and management. 61
23608257 2013
8
Takayasu disease revealed by bilateral loss of vision. 61
25391067 2009
9
A single-center experience treating renal malperfusion after aortic dissection with central aortic fenestration and renal artery stenting. 61
18455638 2008
10
Prevalence of renal artery stenosis in 1,656 patients who have undergone cardiac catheterization. 61
17057922 2006
11
Functional renal artery obstruction following percutaneous kidney biopsy. 61
15840676 2005
12
Renovascular hypertension due to antithrombin deficiency in childhood. 61
15338392 2004
13
Clinical insights into the diagnosis and management of renovascular disease. An evidence-based review. 61
15467512 2004
14
The diagnosis and management of renovascular disease: a primary care perspective. Part I. Making the diagnosis. 61
12826784 2003
15
Balloon angioplasty versus medical therapy for hypertensive patients with renal artery obstruction. 61
12917937 2003
16
An evidence-based approach to diagnosing renovascular hypertension. 61
11602079 2001
17
Renal artery disease in the elderly. 61
10518251 1999
18
Ischemic disease of the kidney: how and why to consider revascularization. 61
9650120 1998
19
Acute bilateral renal artery occlusion due to granulomatous and necrotizing vasculitis. 61
9509569 1998
20
Renovascular hypertension with low-to-normal plasma renin: clinical and angiographic features. 61
9486089 1997
21
[The successful percutaneous revascularization of a subacute renal artery obstruction]. 61
9156604 1997
22
[Renal artery obstruction: from experimental models to logical approach to diagnosis and treatment]. 61
8763013 1996
23
Long-term immunosuppressive treatment of a child with Takayasu's arteritis and high IgE immunoglobulins. 61
8611360 1996
24
Options for therapy of ischemic nephropathy: role of angioplasty and surgery. 61
8720086 1996
25
Excess prevalence of supraaortic artery lesions in renovascular hypertension: an arteriographic study. 61
7820835 1994
26
Labeled lectin studies of renal tubular dysgenesis and renal tubular atrophy of postnatal renal ischemia and end-stage kidney disease. 61
8159624 1994
27
[Color-Doppler and angioplasty in renovascular hypertension]. 61
8332815 1993
28
Acute non-traumatic obstructions of the renal artery. 61
1572872 1992
29
[Complete anuria in unilateral renal artery obstruction and ischemic nephropathy]. 61
1879329 1991
30
[The isolation of the contribution of the parenchyma to the radionephrogram and the assessment of kidney purifying function]. 61
2374481 1990
31
I-131-orthoiodohippurate renal function test in detection of renal artery occlusion in aortic dissection. 61
2168248 1990
32
Increased hematocrit mitigates ischemic renal damage in the splenectomized dog. 61
2923139 1989
33
Myoglobinuria exacerbates ischemic renal damage in the dog. 61
2797346 1989
34
Thrombosis of the renal artery of a small, solitary kidney: successful return of renal function after prolonged anuria. 61
15227264 1988
35
Reversal of renal failure after revascularization in atheromatous renovascular disease. Report of two cases. 61
3218663 1988
36
Renal artery obstruction. 61
3994091 1985
37
[Regional lytic therapy of acute renal artery obstruction]. 61
6697931 1984
38
Renovascular hypertension in black patients. 61
7040233 1982
39
Successful revascularization of early posttransplant renal arterial occlusion. 61
7036393 1982
40
Renal subcapsular rim sign: new etiologies and pathogenesis. 61
6976711 1982
41
Anuria secondary to renal artery obstruction in a solitary kidney: 9-year followup. 61
712908 1978
42
Emergency uroradiology for the nontraumatized patient. 61
684204 1978
43
Revascularization of the ischemic kidney. 61
626586 1978
44
[Collateral circulation through uretral arteries caused by chronical central renal artery obstruction (author's transl)]. 61
625855 1978
45
[Pheochromocytoma with scalloping of the ureter (author's transl)]. 61
1273304 1976
46
Thoracic aorta-to-femoral artery by-pass. For the treatment of complete obstruction of the abdominal aorta at the level of the renal arteries. 61
1184674 1975
47
[Proceedings: Case of left renal artery obstruction caused by an extensive dissecting aortic aneurysm]. 61
1121064 1975
48
[Reconstructive surgery in threatening uremia due to renal artery obstruction]. 61
1123938 1975
49
[Non-traumatic acute renal artery obstruction]. 61
4272781 1973
50
Renin in hypertension: how important as a risk factor? 61
4355135 1973

Variations for Renal Artery Obstruction

Expression for Renal Artery Obstruction

Search GEO for disease gene expression data for Renal Artery Obstruction.

Pathways for Renal Artery Obstruction

GO Terms for Renal Artery Obstruction

Biological processes related to Renal Artery Obstruction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 regulation of blood pressure GO:0008217 9.43 REN ACE
2 activation of adenylate cyclase activity GO:0007190 9.4 ADORA3 ADORA2B
3 positive regulation of blood pressure GO:0045777 9.37 ADORA1 ACE
4 amyloid-beta metabolic process GO:0050435 9.32 REN ACE
5 angiotensin maturation GO:0002003 9.26 REN ACE
6 positive regulation of systemic arterial blood pressure GO:0003084 9.16 ADORA1 ACE
7 relaxation of vascular smooth muscle GO:0060087 8.96 ADORA2B ADORA1
8 adenosine receptor signaling pathway GO:0001973 8.8 ADORA3 ADORA2B ADORA1

Molecular functions related to Renal Artery Obstruction according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 endopeptidase activity GO:0004175 8.96 REN ACE
2 G protein-coupled adenosine receptor activity GO:0001609 8.8 ADORA3 ADORA2B ADORA1

Sources for Renal Artery Obstruction

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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