MCID: RNL004
MIFTS: 21

Renal Pelvis Adenocarcinoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Renal Pelvis Adenocarcinoma

MalaCards integrated aliases for Renal Pelvis Adenocarcinoma:

Name: Renal Pelvis Adenocarcinoma 12 15 70
Adenocarcinoma of the Kidney Pelvis 12
Adenocarcinoma of Renal Pelvis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4918
NCIt 50 C6143
UMLS 70 C1335748

Summaries for Renal Pelvis Adenocarcinoma

Disease Ontology : 12 A renal pelvis carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Renal Pelvis Adenocarcinoma, also known as adenocarcinoma of the kidney pelvis, is related to mucinous adenocarcinoma and villous adenoma. An important gene associated with Renal Pelvis Adenocarcinoma is HCK (HCK Proto-Oncogene, Src Family Tyrosine Kinase), and among its related pathways/superpathways is Cytoskeletal Signaling. Affiliated tissues include kidney, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Renal Pelvis Adenocarcinoma

Diseases related to Renal Pelvis Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 293)
# Related Disease Score Top Affiliating Genes
1 mucinous adenocarcinoma 30.5 KRT7 KRT19 CEACAM5
2 villous adenoma 30.2 KRT7 CEACAM5
3 collecting duct carcinoma 30.0 PAX8 KRT7 KRT19
4 papillary adenocarcinoma 29.0 SLC2A1 KRT7 KRT19 CEACAM5 CDH1
5 appendix adenocarcinoma 10.5
6 hydronephrosis 10.3
7 bladder benign neoplasm 10.2 PAX8 KRT7
8 nephrogenic adenoma of urinary bladder 10.2 PAX8 KRT7
9 nephrogenic adenoma 10.2 PAX8 KRT7
10 wolffian duct adenoma 10.2 PAX8 KRT7
11 clear cell adenocarcinoma 10.2 PAX8 KRT7
12 bartholin's gland carcinoma 10.2 PAX8 KRT7
13 rare tumor 10.2
14 ovarian seromucinous carcinoma 10.2 PAX8 KRT7
15 urethral diverticulum 10.2 PAX8 KRT7
16 ovarian large-cell neuroendocrine carcinoma 10.2 PAX8 KRT7
17 bile duct adenoma 10.2 KRT7 KRT19
18 wolffian duct adenocarcinoma 10.2 PAX8 KRT7
19 uterus perivascular epithelioid cell tumor 10.2 PAX8 KRT7
20 nephrogenic adenoma of the urethra 10.2 PAX8 KRT7
21 cystadenofibroma 10.2 PAX8 KRT7
22 renal adenoma 10.2 PAX8 KRT7
23 thymus clear cell carcinoma 10.2 PAX8 KRT7
24 bladder clear cell adenocarcinoma 10.2 PAX8 KRT7
25 endosalpingiosis 10.2 PAX8 KRT7
26 cervical adenoma malignum 10.2 PAX8 KRT7
27 proliferating trichilemmal cyst 10.2 KRT7 KRT19
28 peritoneal serous adenocarcinoma 10.2 PAX8 KRT7
29 epithelioid cell synovial sarcoma 10.2 PAX8 KRT7
30 urethra clear cell adenocarcinoma 10.2 PAX8 KRT7
31 intrahepatic gall duct cancer 10.2 KRT7 KRT19
32 bartholin's gland adenocarcinoma 10.2 PAX8 KRT7
33 squamous cell bile duct carcinoma 10.2 KRT7 KRT19
34 lipoadenoma 10.2 KRT7 KRT19
35 pulmonary artery leiomyosarcoma 10.2 KRT7 KRT19
36 female reproductive endometrioid cancer 10.2 PAX8 KRT7
37 mucinous tubular and spindle renal cell carcinoma 10.2 KRT7 KRT19
38 gallbladder signet ring cell adenocarcinoma 10.2 KRT7 CDH1
39 kidney benign neoplasm 10.2 PAX8 KRT7
40 mixed fibrolamellar hepatocellular carcinoma 10.2 KRT7 KRT19
41 ceruminous adenocarcinoma 10.2 SLC2A1 KRT7
42 uterus leiomyosarcoma 10.2 KRT7 KRT19
43 benign struma ovarii 10.2 PAX8 KRT19
44 uterine corpus sarcoma 10.2 KRT7 KRT19
45 adenocarcinoma 10.2
46 suppurative thyroiditis 10.1 KRT7 KRT19
47 biphasic synovial sarcoma 10.1 PAX8 CDH1
48 monophasic synovial sarcoma 10.1 KRT7 KRT19
49 hidradenoma 10.1 KRT7 CEACAM5
50 papillary adenoma 10.1 KRT7 CEACAM5

Graphical network of the top 20 diseases related to Renal Pelvis Adenocarcinoma:



Diseases related to Renal Pelvis Adenocarcinoma

Symptoms & Phenotypes for Renal Pelvis Adenocarcinoma

GenomeRNAi Phenotypes related to Renal Pelvis Adenocarcinoma according to GeneCards Suite gene sharing:

26 (show all 17)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-112 9.58 SLC2A1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-138 9.58 SLC2A1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-146 9.58 KRT19
4 Increased shRNA abundance (Z-score > 2) GR00366-A-166 9.58 PAX8
5 Increased shRNA abundance (Z-score > 2) GR00366-A-169 9.58 KRT19
6 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.58 KRT19
7 Increased shRNA abundance (Z-score > 2) GR00366-A-179 9.58 HCK
8 Increased shRNA abundance (Z-score > 2) GR00366-A-2 9.58 HCK
9 Increased shRNA abundance (Z-score > 2) GR00366-A-34 9.58 KRT19
10 Increased shRNA abundance (Z-score > 2) GR00366-A-41 9.58 SLC2A1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.58 KRT19 SLC2A1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-58 9.58 SLC2A1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-60 9.58 HCK
14 Increased shRNA abundance (Z-score > 2) GR00366-A-75 9.58 KRT19
15 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.58 KRT19
16 Increased shRNA abundance (Z-score > 2) GR00366-A-85 9.58 HCK
17 Increased shRNA abundance (Z-score > 2) GR00366-A-99 9.58 HCK

Drugs & Therapeutics for Renal Pelvis Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Renal Pelvis Adenocarcinoma

Genetic Tests for Renal Pelvis Adenocarcinoma

Anatomical Context for Renal Pelvis Adenocarcinoma

MalaCards organs/tissues related to Renal Pelvis Adenocarcinoma:

40
Kidney

Publications for Renal Pelvis Adenocarcinoma

Articles related to Renal Pelvis Adenocarcinoma:

# Title Authors PMID Year
1
[Clinicopathologic features with collecting duct carcinoma of kidney: report of 10 cases]. 61
29429165 2018
2
[Tubulovillous adenocarcinoma of the renal pelvis. Case report]. 61
17190219 2006
3
[Adenocarcinoma of the kidney pelvis]. 61
2694806 1989
4
[Primary adenocarcinoma of the kidney pelvis. Apropos of a case]. 61
4793148 1973

Variations for Renal Pelvis Adenocarcinoma

Expression for Renal Pelvis Adenocarcinoma

Search GEO for disease gene expression data for Renal Pelvis Adenocarcinoma.

Pathways for Renal Pelvis Adenocarcinoma

Pathways related to Renal Pelvis Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.29 KRT7 KRT19 CDH1

GO Terms for Renal Pelvis Adenocarcinoma

Cellular components related to Renal Pelvis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cortical actin cytoskeleton GO:0030864 8.62 SLC2A1 CDH1

Sources for Renal Pelvis Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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