MCID: RNL004
MIFTS: 27

Renal Pelvis Adenocarcinoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Renal Pelvis Adenocarcinoma

MalaCards integrated aliases for Renal Pelvis Adenocarcinoma:

Name: Renal Pelvis Adenocarcinoma 12 15 73
Adenocarcinoma of the Kidney Pelvis 12
Adenocarcinoma of Renal Pelvis 12

Classifications:



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Disease Ontology 12 DOID:4918
NCIt 50 C6143
UMLS 73 C1335748

Summaries for Renal Pelvis Adenocarcinoma

Disease Ontology : 12 A renal pelvis carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Renal Pelvis Adenocarcinoma, also known as adenocarcinoma of the kidney pelvis, is related to nephrogenic adenoma of urinary bladder and bladder benign neoplasm. An important gene associated with Renal Pelvis Adenocarcinoma is PAX8 (Paired Box 8), and among its related pathways/superpathways is Cytoskeletal Signaling. Affiliated tissues include kidney, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Renal Pelvis Adenocarcinoma

Diseases related to Renal Pelvis Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 108)
# Related Disease Score Top Affiliating Genes
1 nephrogenic adenoma of urinary bladder 10.5 KRT7 PAX8
2 bladder benign neoplasm 10.5 KRT7 PAX8
3 endosalpingiosis 10.5 KRT7 PAX8
4 endocervical carcinoma 10.5 KRT7 PAX8
5 nephrogenic adenoma 10.4 KRT7 PAX8
6 kidney benign neoplasm 10.4 KRT7 PAX8
7 endocervical adenocarcinoma 10.4 KRT7 PAX8
8 urethral diverticulum 10.4 KRT7 PAX8
9 collecting duct carcinoma 10.4 KRT7 PAX8
10 adenocarcinoma in situ 10.4 KRT7 PAX8
11 childhood endodermal sinus tumor 10.4 AFP PAX8
12 cellular schwannoma 10.3 PAX8 SLC2A1
13 nephrogenic adenofibroma 10.3 KRT7 PAX8
14 clear cell adenofibroma 10.3 KRT7 SLC2A1
15 anal gland adenocarcinoma 10.3 KRT19 KRT7
16 proliferating trichilemmal cyst 10.3 KRT19 KRT7
17 anus adenocarcinoma 10.3 KRT19 KRT7
18 cutaneous adenocystic carcinoma 10.3 KRT19 KRT7
19 rete testis neoplasm 10.3 AFP PAX8
20 eccrine adenocarcinoma 10.3 KRT19 KRT7
21 bladder carcinoma in situ 10.3 KRT19 KRT7
22 ovarian brenner tumor 10.3 KRT7 PAX8
23 malignant leydig cell tumor 10.3 KRT19 KRT7
24 corneal abscess 10.3 KRT19 KRT7
25 anal canal adenocarcinoma 10.3 KRT19 KRT7
26 chondroid lipoma 10.3 KRT19 KRT7
27 spindle cell synovial sarcoma 10.3 KRT7 SLC2A1
28 mucinous tubular and spindle renal cell carcinoma 10.2 KRT19 KRT7
29 biliary papillomatosis 10.2 KRT19 KRT7
30 adenocarcinoma 10.2
31 lipoadenoma 10.2 KRT19 KRT7
32 immune system organ benign neoplasm 10.2 KRT19 KRT7
33 thymus lipoma 10.2 KRT19 KRT7
34 follicular adenoma 10.2 KRT19 PAX8
35 pericardium cancer 10.2 KRT19 KRT7
36 mucinous adenocarcinoma 10.2
37 ovarian germ cell cancer 10.2 AFP KRT7
38 bile duct cystadenocarcinoma 10.2 AFP KRT7
39 intratubular embryonal carcinoma 10.2 AFP KRT7
40 malignant struma ovarii 10.1 AFP KRT19
41 choriocarcinoma of the testis 10.1 AFP KRT7
42 adenomatoid tumor 10.1 AFP KRT7
43 seminal vesicle tumor 10.1 AFP KRT7
44 sertoli-leydig cell tumor 10.1 AFP KRT7
45 pericardial mesothelioma 10.1 KRT19 KRT7
46 malignant biphasic mesothelioma 10.1 AFP KRT7
47 ovarian endodermal sinus tumor 10.1 AFP KRT7
48 white sponge nevus 1 10.1 KRT19 KRT7
49 renal cell carcinoma, papillary, 1 10.1 KRT7 PAX8
50 ovarian primitive germ cell tumor 10.1 AFP KRT7

Graphical network of the top 20 diseases related to Renal Pelvis Adenocarcinoma:



Diseases related to Renal Pelvis Adenocarcinoma

Symptoms & Phenotypes for Renal Pelvis Adenocarcinoma

GenomeRNAi Phenotypes related to Renal Pelvis Adenocarcinoma according to GeneCards Suite gene sharing:

26 (show all 30)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-114 10.19 AFP
2 Increased shRNA abundance (Z-score > 2) GR00366-A-120 10.19 AFP
3 Increased shRNA abundance (Z-score > 2) GR00366-A-126 10.19 HCK
4 Increased shRNA abundance (Z-score > 2) GR00366-A-130 10.19 HCK
5 Increased shRNA abundance (Z-score > 2) GR00366-A-135 10.19 KRT7
6 Increased shRNA abundance (Z-score > 2) GR00366-A-138 10.19 SLC2A1
7 Increased shRNA abundance (Z-score > 2) GR00366-A-146 10.19 KRT19
8 Increased shRNA abundance (Z-score > 2) GR00366-A-147 10.19 SLC2A1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-152 10.19 SLC2A1
10 Increased shRNA abundance (Z-score > 2) GR00366-A-166 10.19 PAX8
11 Increased shRNA abundance (Z-score > 2) GR00366-A-169 10.19 KRT19
12 Increased shRNA abundance (Z-score > 2) GR00366-A-176 10.19 SLC2A1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-177 10.19 KRT19
14 Increased shRNA abundance (Z-score > 2) GR00366-A-192 10.19 AFP KRT7
15 Increased shRNA abundance (Z-score > 2) GR00366-A-2 10.19 HCK
16 Increased shRNA abundance (Z-score > 2) GR00366-A-214 10.19 HCK
17 Increased shRNA abundance (Z-score > 2) GR00366-A-25 10.19 PAX8
18 Increased shRNA abundance (Z-score > 2) GR00366-A-29 10.19 AFP
19 Increased shRNA abundance (Z-score > 2) GR00366-A-3 10.19 PAX8
20 Increased shRNA abundance (Z-score > 2) GR00366-A-41 10.19 PAX8 SLC2A1
21 Increased shRNA abundance (Z-score > 2) GR00366-A-43 10.19 PAX8 SLC2A1 HCK KRT19
22 Increased shRNA abundance (Z-score > 2) GR00366-A-63 10.19 AFP
23 Increased shRNA abundance (Z-score > 2) GR00366-A-74 10.19 KRT7
24 Increased shRNA abundance (Z-score > 2) GR00366-A-81 10.19 PAX8
25 Increased shRNA abundance (Z-score > 2) GR00366-A-85 10.19 HCK
26 Increased shRNA abundance (Z-score > 2) GR00366-A-9 10.19 SLC2A1
27 Increased shRNA abundance (Z-score > 2) GR00366-A-90 10.19 SLC2A1
28 Increased shRNA abundance (Z-score > 2) GR00366-A-93 10.19 PAX8
29 Increased shRNA abundance (Z-score > 2) GR00366-A-99 10.19 HCK
30 Reduced mammosphere formation GR00396-S 8.92 AFP PAX8 CDH1 KRT7

MGI Mouse Phenotypes related to Renal Pelvis Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 endocrine/exocrine gland MP:0005379 9.65 AFP CDH1 HCK KRT19 PAX8
2 homeostasis/metabolism MP:0005376 9.63 AFP CDH1 HCK KRT7 PAX8 SLC2A1
3 neoplasm MP:0002006 9.26 AFP CDH1 HCK KRT19
4 no phenotypic analysis MP:0003012 8.92 CDH1 KRT19 PAX8 SLC2A1

Drugs & Therapeutics for Renal Pelvis Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Renal Pelvis Adenocarcinoma

Genetic Tests for Renal Pelvis Adenocarcinoma

Anatomical Context for Renal Pelvis Adenocarcinoma

MalaCards organs/tissues related to Renal Pelvis Adenocarcinoma:

41
Kidney

Publications for Renal Pelvis Adenocarcinoma

Articles related to Renal Pelvis Adenocarcinoma:

# Title Authors Year
1
Presentation of mucinous adenocarcinoma of renal pelvis masquerading as gross hydronephrosis: A histopathological surprise. ( 28702413 )
2017
2
Alpha-fetoprotein and carbohydrate antigen 19-9 producing advanced adenocarcinoma of renal pelvis and ureter. ( 24282469 )
2013
3
Re: Ho et al.: Primary mucinous adenocarcinoma of renal pelvis with carcinoembryonic antigen production. (Urology 2008;71:e7-e8). ( 19646634 )
2009
4
Primary mucinous adenocarcinoma of renal pelvis with carcinoembryonic antigen production. ( 18291507 )
2008
5
Mucinous adenocarcinoma of renal pelvis and villous adenoma of bladder after a caecal augmentation of bladder. ( 10075375 )
1999
6
Primary mucinous adenocarcinoma of renal pelvis in solitary pelvic kidney. ( 8382888 )
1993
7
Mucinous adenocarcinoma of renal pelvis. ( 6287692 )
1982

Variations for Renal Pelvis Adenocarcinoma

Expression for Renal Pelvis Adenocarcinoma

Search GEO for disease gene expression data for Renal Pelvis Adenocarcinoma.

Pathways for Renal Pelvis Adenocarcinoma

Pathways related to Renal Pelvis Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.29 CDH1 KRT19 KRT7

GO Terms for Renal Pelvis Adenocarcinoma

Cellular components related to Renal Pelvis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 caveola GO:0005901 8.96 HCK SLC2A1
2 cortical actin cytoskeleton GO:0030864 8.62 CDH1 SLC2A1

Biological processes related to Renal Pelvis Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 viral process GO:0016032 8.8 HCK KRT19 KRT7

Sources for Renal Pelvis Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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