MCID: RNL012
MIFTS: 32

Renal Tuberculosis

Categories: Infectious diseases, Nephrological diseases

Aliases & Classifications for Renal Tuberculosis

MalaCards integrated aliases for Renal Tuberculosis:

Name: Renal Tuberculosis 12 15 17
Tuberculosis, Renal 43 71
Tuberculosis of Kidney 12
Tuberculosis Renal 54

Classifications:



External Ids:

Disease Ontology 12 DOID:9733
ICD9CM 34 016.0 016.00
MeSH 43 D014398
NCIt 49 C123020
SNOMED-CT 67 44323002
UMLS 71 C0041328

Summaries for Renal Tuberculosis

Disease Ontology : 12 An urogenital tuberculosis that results in formation of granulomas located in kidney.

MalaCards based summary : Renal Tuberculosis, also known as tuberculosis, renal, is related to pyuria and xanthogranulomatous pyelonephritis. An important gene associated with Renal Tuberculosis is XCL1 (X-C Motif Chemokine Ligand 1). The drugs interferons and Interferon-gamma have been mentioned in the context of this disorder. Affiliated tissues include kidney, testes and skin.

Related Diseases for Renal Tuberculosis

Diseases related to Renal Tuberculosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 116)
# Related Disease Score Top Affiliating Genes
1 pyuria 30.3 NEXMIF B2M
2 xanthogranulomatous pyelonephritis 30.1 NEXMIF ERVMER34-1
3 interstitial nephritis 29.8 REN B2M
4 urogenital tuberculosis 29.7 SLC26A6 NEXMIF ERVMER34-1
5 hydronephrosis 29.7 REN B2M
6 chronic pyelonephritis 29.3 REN NEXMIF B2M
7 vesicoureteral reflux 1 29.3 REN B2M
8 acute kidney failure 29.3 REN B2M
9 urinary tract obstruction 29.2 REN B2M
10 pyelitis 29.0 REN NEXMIF B2M
11 uremia 29.0 REN B2M
12 congenital anomalies of kidney and urinary tract 2 28.4 STK10 REN ERVMER34-1
13 mycobacterium tuberculosis 1 11.0
14 pyelonephritis 10.3
15 pulmonary tuberculosis 10.2
16 renal cell carcinoma, nonpapillary 10.1
17 kidney disease 10.1
18 bladder cancer 10.0
19 kidney cancer 10.0
20 cystitis 10.0
21 end stage renal failure 10.0
22 nephrolithiasis, calcium oxalate 9.9
23 extrapulmonary tuberculosis 9.9
24 cystic kidney disease 9.9
25 adenocarcinoma 9.9
26 sarcoidosis 1 9.8
27 leprosy 3 9.8
28 polycystic kidney disease 9.8
29 nephrotic syndrome 9.8
30 acute cystitis 9.8
31 transitional cell carcinoma 9.8
32 acquired immunodeficiency syndrome 9.8
33 peritonitis 9.8
34 vasculitis 9.8
35 lupus erythematosus 9.8
36 hansen's disease 9.8
37 lymphocele 9.7 STK10 ERVMER34-1
38 bladder tuberculosis 9.7 STK10 ERVMER34-1
39 cholecystolithiasis 9.7 STK10 ERVMER34-1
40 heart conduction disease 9.7 REN HCN4
41 common bile duct disease 9.7 STK10 ERVMER34-1
42 cecal disease 9.7 STK10 ERVMER34-1
43 renal tubular acidosis 9.7 SLC26A6 REN
44 fanconi renotubular syndrome 1 9.6
45 systemic lupus erythematosus 9.6
46 otitis media 9.6
47 tuberous sclerosis 1 9.6
48 immune deficiency disease 9.6
49 kala-azar 1 9.6
50 severe cutaneous adverse reaction 9.6

Graphical network of the top 20 diseases related to Renal Tuberculosis:



Diseases related to Renal Tuberculosis

Symptoms & Phenotypes for Renal Tuberculosis

Drugs & Therapeutics for Renal Tuberculosis

Drugs for Renal Tuberculosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 interferons
2 Interferon-gamma
3 Antiviral Agents
4 Anti-Infective Agents

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Phase I, Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics and Safety of Pretomanid in Subjects With Renal Impairment Compared to Subjects With Normal Renal Function Recruiting NCT03896750 Phase 1 PA-824
2 A Randomized Study for Screening Latent Tuberculosis Infection and Observing Preventive Therapy in Patients Preparing for Kidney Transplantation Unknown status NCT02782416
3 Interferon-Gamma Release Assays (IGRA) Versus Tuberculin Skin Testing for Detection of Latent Tuberculosis Infection (TB) in Chronic Hemodialysis Patients Completed NCT00695734
4 Surveillance and Follow-up for Latent Tuberculosis Infection and Risk of Developing Active Tuberculosis in Patients Receiving Long-term Dialysis Completed NCT01311999

Search NIH Clinical Center for Renal Tuberculosis

Cochrane evidence based reviews: tuberculosis, renal

Genetic Tests for Renal Tuberculosis

Anatomical Context for Renal Tuberculosis

The Foundational Model of Anatomy Ontology organs/tissues related to Renal Tuberculosis:

19
Kidney

MalaCards organs/tissues related to Renal Tuberculosis:

40
Kidney, Testes, Skin, Heart, Bone, Lung, Neutrophil

Publications for Renal Tuberculosis

Articles related to Renal Tuberculosis:

(show top 50) (show all 1348)
# Title Authors PMID Year
1
Changes in urinary excretion of endothelin-1-like immunoreactivity before and after unilateral nephrectomy in humans. Comparison with other urinary parameters and unilateral adrenalectomy. 54 61
8072606 1994
2
Application of whole-genome sequencing in a case study of renal tuberculosis in a child. 61
32024474 2020
3
Renal tuberculosis following BCG therapy for bladder cancer. 61
31608929 2019
4
A case of renal tuberculosis following BCG therapy for bladder cancer. 61
31346620 2019
5
Renal tuberculosis mimicking renal cell carcinoma: a case report. 61
31077255 2019
6
Unknown primary Merkel cell carcinoma with cutaneous spread. 61
30796073 2019
7
Evaluation of cases of pediatric extrapulmonary tuberculosis: a single center experience. 61
31384143 2019
8
Analysis of 17 children with renal abscess. 61
31934162 2019
9
Two unusual reports of urogenital tuberculosis: One 'putty' kidney and another in association with benign prostatic hyperplasia. 61
30522625 2018
10
Tuberculosis treatment failure in AIDS: vengeance with renal and ocular manifestations. 61
30171156 2018
11
The role of HCN channels in peristaltic dysfunction in human ureteral tuberculosis. 61
29460132 2018
12
[Nephrotuberculosis and urolithiasis]. 61
29634134 2018
13
Multidetector computed tomography has replaced conventional intravenous excretory urography in imaging of the kidneys: A scoping review of multidetector computed tomography findings in renal tuberculosis. 61
31754491 2018
14
Issues in access to end-of-life care in low-resource areas. 61
29251606 2018
15
Renal Tuberculosis Following Intravesical Bacillus Calmette-Guérin for High-grade Non-muscle-invasive Bladder Cancer. 61
28577928 2017
16
Renal Tuberculosis in a 9 Months Old: Case Report and Review of the Literature. 61
28462170 2017
17
Risk Factors Related with Retroperitoneal Laparoscopic Converted to Open Nephrectomy for Nonfunctioning Renal Tuberculosis. 61
28358254 2017
18
Compulsory notification at skilled nursing facilities. 61
28724043 2017
19
Analysis of the association between Mycobacterium tuberculosis infection and Immunoglobulin A nephropathy by early secreted antigenic target 6 detection in renal biopsies: a prospective study. 61
28135876 2017
20
Early Diagnosis of Tuberculosis-Associated IgA Nephropathy with ESAT-6. 61
28392505 2017
21
Isolated Renal Mucormycosis. 61
28527169 2017
22
Invasive squamous cell bladder cancer of the ureterovesical junction in a renal transplant patient: a case report. 61
28479974 2017
23
Clinicopathological analysis of renal inflammatory pseudotumors presenting as the unilateral solitary masses. 61
31966620 2017
24
Gross Hematuria Is More Common in Male and Older Patients with Renal Tuberculosis in China: A Single-Center 15-Year Clinical Experience. 61
28343213 2017
25
Pseudotumor presentation of renal tuberculosis mimicking renal cell carcinoma: A rare entity. 61
27635298 2016
26
Small renal tumor with lymph nodal enlargement: A histopathological surprise. 61
27453671 2016
27
Renal tuberculosis presenting as acute pyelonephritis - A rarity. 61
27865246 2016
28
[Experimental study of GeneXpert(®) system in the diagnosis of extra-pulmonary tuberculosis]. 61
27430924 2016
29
Spontaneous Nephrocutaneous Fistula With Tuberculous Autonephrectomy: A Case Report of a Delayed Diagnosis. 61
27621917 2016
30
Chronic kidney disease related to renal tuberculosis: a case report. 61
27384842 2016
31
Prevalence of Fabry disease in dialysis patients: Japan Fabry disease screening study (J-FAST). 61
26197777 2016
32
Stage 5-CKD under nephrology care: to dialyze or not to dialyze, that is the question. 61
26584810 2016
33
Renal tuberculosis with lobar calcification. 61
27051143 2016
34
[The Great Imitator. Case report]. 61
26895803 2016
35
Renal Tuberculosis Presenting as a Mass Lesion in a Two-year-old Girl: Report of a rare case. 61
26909199 2016
36
Spontaneous Nephrocutaneous Fistula: A Case Report, Update of the Literature and Management Algorithm. 61
25115272 2016
37
Renal tuberculosis tends to be low symptoms: how to improve the diagnosis and treatment of renal tuberculosis. 61
25791732 2016
38
Open surgery versus retroperitoneal laparoscopic nephrectomy for renal tuberculosis: a retrospective study of 120 patients. 61
27917313 2016
39
Clinical Scenarios in Chronic Kidney Disease: Chronic Tubulointerstitial Diseases. 61
27169608 2016
40
A kidney's ingenious path to trimillennar preservation: Renal tuberculosis in an Egyptian mummy? 61
28802970 2015
41
Clinical analysis of retroperitoneoscopic nephroureterectomy for renal tuberculosis. 61
29063010 2015
42
Reply: Challenges in the diagnosis of renal tuberculosis. 61
26362964 2015
43
Hydronephrotic Kidney Previously Treated for Tuberculosis: Rare Primary Squamous Cell Carcinoma of Renal Pelvis Diagnosed by Fine-needle Aspiration Cytology. 61
26793542 2015
44
Challenges in the diagnosis of renal tuberculosis. 61
26362963 2015
45
Extensive nephroureteric calcification presenting with renal failure: A rare case report. 61
26229330 2015
46
Dual Time Point (18)F-FDG PET/CT Imaging Identifies Bilateral Renal Tuberculosis in an Immunocompromised Patient with an Unknown Primary Malignancy. 61
26157590 2015
47
Discovery of Renal Tuberculosis in a Partial Nephrectomy Specimen Done for Renal Tumor. 61
26793504 2015
48
Renal tuberculosis: a case report. 61
26017107 2015
49
Systemic lupus erythematosus accompanying with renal tuberculosis: a case report. 61
26221395 2015
50
Is Urinary Lipoarabinomannan the Result of Renal Tuberculosis? Assessment of the Renal Histology in an Autopsy Cohort of Ugandan HIV-Infected Adults. 61
25897661 2015

Variations for Renal Tuberculosis

Expression for Renal Tuberculosis

Search GEO for disease gene expression data for Renal Tuberculosis.

Pathways for Renal Tuberculosis

GO Terms for Renal Tuberculosis

Biological processes related to Renal Tuberculosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to interferon-gamma GO:0071346 9.16 XCL1 SLC26A6
2 cellular response to cAMP GO:0071320 8.96 SLC26A6 HCN4
3 positive regulation of T cell cytokine production GO:0002726 8.62 XCL1 B2M

Sources for Renal Tuberculosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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